Alignment of the gene Family HBG000208 of HOVERGEN

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Threshold: 50% 80% 100%
Size: Bigger Smaller Normal
Isoforms are ON
Q4T280_TETNG Q4T280_TETNG RLIRFKSIMGLHSAQKKHFPLRGIDGVVQL---FEAELHKPE-PDLALLSLVLGFVEHFL Q9PU64_DANRE Q9PU64_DANRE --------MGIRSTQKKHFPLRGIDGVVQL---FESELNSPE-PDLALLSLVLGFVEHFL Q503J8_DANRE Q503J8_DANRE --------MGIRSTQKKHFPLRGIDGVVQL---FESELNSPE-PDLALLSLVLGFVEHFL Q804R6_DANRE Q804R6_DANRE --------MGIRSTQKKHFPLRGIDGVVQL---FESELNSPE-PDLALLSLVLGFVEHFL Q5VSN4_DANRE Q5VSN4_DANRE --------MGIRSTQKKHFPLRGIDGVVQL---FESELNSSE-PDLALLSLVLGFVEHFL Q9IAA9_DANRE Q9IAA9_DANRE --------MGIRSTQKKHFPLRGIDGVVQL---FESELNSPE-PDLALLSLVLGFVEHFL B2KIB7_RHIFE B2KIB7_RHIFE -----------------------MEECLRSGCRLGVEGGREHGPSL-------------- B3RF41_SORAR B3RF41_SORAR --------MGLKAAQKTLFPLRSIDDVVRL---FAAELGREE-PDLVLLSLVLGFVEHFL A5HBC9_HUMAN A5HBC9_HUMAN --------MGLKAAQKTLFPLRSIDDVVRL---FAAELGREE-PDLVLLSLVLGFVEHFL B5SNL0_OTOGA B5SNL0_OTOGA --------MGLKAAQKTLFPLRSIDDVVRL---FAAELGREE-PDLVLLSLVLGFVEHFL Q9WVR8_RAT Q9WVR8_RAT --------MGLKAAQKTLFPLRSIDDVVRL---FAAELGREE-PDLVLLSLVLGFVEHFL Q5NDM1_PRANA Q5NDM1_PRANA --------MGLKAAQKTLFPLRSIDDVVRL---FAAELGREE-PDLVLLSLVLGFVEHFL MEN1_MOUSE MEN1_MOUSE --------MGLKAAQKTLFPLRSIDDVVRL---FAAELGREE-PDLVLLSLVLGFVEHFL Q8CI72_MOUSE Q8CI72_MOUSE --------MGLKAAQKTLFPLRSIDDVVRL---FAAELGREE-PDLVLLSLVLGFVEHFL Q3U491_MOUSE Q3U491_MOUSE --MPPPAAMGLKAAQKTLFPLRSIDDVVRL---FAAELGREE-PDLVLLSLVLGFVEHFL Q91UZ7_MOUSE Q91UZ7_MOUSE --------MGLKAAQKTLFPLRSIDDVVRL---FAAELGREE-PDLVLLSLVLGFVEHFL Q0P5I0_BOVIN Q0P5I0_BOVIN --------MGLKAAQKTLFPLRSIDDVVRL---FAAELGREE-PDLVLLSLVLGFVEHFL A2SXS5_CANFA A2SXS5_CANFA --------MGLKAAQKTLFPLRSIDDVVRL---FAAELGREE-PDLVLLSLVLGFVEHFL B5APJ3_MUSPF B5APJ3_MUSPF --------MGLKAAQKTLFPLRSIDDVVRL---FAAELGREE-PDLVLLSLVLGFVEHFL Q5GN71_FELCA Q5GN71_FELCA --------K---AAQKTLFPLRSIDDVVRL---FAAELGREE-PDLVLLSLVLGFVEHFL B0CM67_PAPAN B0CM67_PAPAN --------MGLKAAQKTLFPLRSIDDVVRL---FAAELGREE-PDLVLLSLVLGFVEHFL A5HBC6_HUMAN A5HBC6_HUMAN --------MGLKAAQKTLFPLRSIDDVVRL---FAAELGREE-PDLVLLSLVLGFVEHFL A5HBC8_HUMAN A5HBC8_HUMAN --------MGLKAAQKTLFPLRSIDDVVRL---FAAELGREE-PDLVLLSLVLGFVEHFL A5HBC7_HUMAN A5HBC7_HUMAN --------MGLKAAQKTLFPLRSIDDVVRL---FAAELGREE-PDLVLLSLVLGFVEHFL A5HBD0_HUMAN A5HBD0_HUMAN --------MGLKAAQKTLFPLRSIDDVVRL---FAAELGREE-PDLVLLSLVLGFVEHFL A5HBD1_HUMAN A5HBD1_HUMAN --------MGLKAAQKTLFPLRSIDDVVRL---FAAELGREE-PDLVLLSLVLGFVEHFL Q9BUF0_HUMAN Q9BUF0_HUMAN ------------------------------------------------------------ Q9UE24_HUMAN Q9UE24_HUMAN ------------------------------------------------------------ MEN1_HUMAN MEN1_HUMAN --------MGLKAAQKTLFPLRSIDDVVRL---FAAELGREE-PDLVLLSLVLGFVEHFL B1MTL6_CALMO B1MTL6_CALMO --------MGLKAAQKTLFPLRSIDDVVRL---FAAELGREE-PDLVLLSLVLGFVEHFL B0KWK5_CALJA B0KWK5_CALJA --------MGLKAAQKTLFPLRSIDDVVRL---FAAELGREE-PDLVLLSLVLGFVEHFL B1H1W4_XENLA B1H1W4_XENLA --------MGLLPTQKSFFPINSLDSLVSL---FQWELSRPE-PDLALLSLTLGFVEHFL Q0IHQ0_XENTR Q0IHQ0_XENTR --------MGLLPTQKSFFPITSLDSLVSL---FQWELSRPE-PDLALLSLTLGFVEHFL MATCH CONSENSUS ????????MG????QK??FPLR?ID?VV?L???F??EL???E?PDL?LLSLVLGFVEHFL

Q4T280_TETNG Q4T280_TETNG AVNRVIPVNVPGV----------------------------------------------- Q9PU64_DANRE Q9PU64_DANRE AVNRVVPVNVPGV----------------------------------------------- Q503J8_DANRE Q503J8_DANRE AVNRVVPVNVPGV----------------------------------------------- Q804R6_DANRE Q804R6_DANRE AVNRVVPVNVPGV----------------------------------------------- Q5VSN4_DANRE Q5VSN4_DANRE AVNRVVPVNVPGV----------------------------------------------- Q9IAA9_DANRE Q9IAA9_DANRE AVNRVVPVNVPGV----------------------------------------------- B2KIB7_RHIFE B2KIB7_RHIFE ------------------------------------------------------------ B3RF41_SORAR B3RF41_SORAR AVNRVIPTNVPEL----------------------------------------------- A5HBC9_HUMAN A5HBC9_HUMAN AVNRVIPTNVPEL----------------------------------------------- B5SNL0_OTOGA B5SNL0_OTOGA AVNRVIPTNVPEL----------------------------------------------- Q9WVR8_RAT Q9WVR8_RAT AVNRVIPTNVPEL----------------------------------------------- Q5NDM1_PRANA Q5NDM1_PRANA AVNRVIPTNVPEL----------------------------------------------- MEN1_MOUSE MEN1_MOUSE AVNRVIPTNVPEL----------------------------------------------- Q8CI72_MOUSE Q8CI72_MOUSE AVNRVIPTNVPEL----------------------------------------------- Q3U491_MOUSE Q3U491_MOUSE AVNRVIPTNVPEL----------------------------------------------- Q91UZ7_MOUSE Q91UZ7_MOUSE AVNRVIPTNVPEL----------------------------------------------- Q0P5I0_BOVIN Q0P5I0_BOVIN AVNRVIPTNVPEL----------------------------------------------- A2SXS5_CANFA A2SXS5_CANFA AVNRVIPTNVPEL----------------------------------------------- B5APJ3_MUSPF B5APJ3_MUSPF AVNRVIPTNVPEL----------------------------------------------- Q5GN71_FELCA Q5GN71_FELCA AVNRVIPTNVPEL----------------------------------------------- B0CM67_PAPAN B0CM67_PAPAN AVNRVIPTNVPEL----------------------------------------------- A5HBC6_HUMAN A5HBC6_HUMAN AVNRVIPTNVPEL----------------------------------------------- A5HBC8_HUMAN A5HBC8_HUMAN AVNRVIPTNVPEL----------------------------------------------- A5HBC7_HUMAN A5HBC7_HUMAN AVNRVIPTNVPEL----------------------------------------------- A5HBD0_HUMAN A5HBD0_HUMAN AVNRVIPTNVPEL----------------------------------------------- A5HBD1_HUMAN A5HBD1_HUMAN AVNRVIPTNVPEL----------------------------------------------- Q9BUF0_HUMAN Q9BUF0_HUMAN ------------------------------------------------------------ Q9UE24_HUMAN Q9UE24_HUMAN ------------------------------------------------------------ MEN1_HUMAN MEN1_HUMAN AVNRVIPTNVPEL----------------------------------------------- B1MTL6_CALMO B1MTL6_CALMO AVNRVIPTNVPEL----------------------------------------------- B0KWK5_CALJA B0KWK5_CALJA AVNRVIPTNVPEL----------------------------------------------- B1H1W4_XENLA B1H1W4_XENLA AVNRVVPTNVASLPDTGPALLAKIGGEGAKVNRKTSVKQGKNESINLEQEKRETRGDLSR Q0IHQ0_XENTR Q0IHQ0_XENTR AVNRVVPTNVSSLPDTGPALLAKIGGEGAKVNRKISSKQGKNESIKAEQGKRETRADITR MATCH CONSENSUS AVNRV?P?NVP?????????????????????????????????????????????????

Q4T280_TETNG Q4T280_TETNG ------------------------------------------------------------ Q9PU64_DANRE Q9PU64_DANRE ------------------------------------------------------------ Q503J8_DANRE Q503J8_DANRE ------------------------------------------------------------ Q804R6_DANRE Q804R6_DANRE ------------------------------------------------------------ Q5VSN4_DANRE Q5VSN4_DANRE ------------------------------------------------------------ Q9IAA9_DANRE Q9IAA9_DANRE ------------------------------------------------------------ B2KIB7_RHIFE B2KIB7_RHIFE ------------------------------------------------------------ B3RF41_SORAR B3RF41_SORAR ------------------------------------------------------------ A5HBC9_HUMAN A5HBC9_HUMAN ------------------------------------------------------------ B5SNL0_OTOGA B5SNL0_OTOGA ------------------------------------------------------------ Q9WVR8_RAT Q9WVR8_RAT ------------------------------------------------------------ Q5NDM1_PRANA Q5NDM1_PRANA ------------------------------------------------------------ MEN1_MOUSE MEN1_MOUSE ------------------------------------------------------------ Q8CI72_MOUSE Q8CI72_MOUSE ------------------------------------------------------------ Q3U491_MOUSE Q3U491_MOUSE ------------------------------------------------------------ Q91UZ7_MOUSE Q91UZ7_MOUSE ------------------------------------------------------------ Q0P5I0_BOVIN Q0P5I0_BOVIN ------------------------------------------------------------ A2SXS5_CANFA A2SXS5_CANFA ------------------------------------------------------------ B5APJ3_MUSPF B5APJ3_MUSPF ------------------------------------------------------------ Q5GN71_FELCA Q5GN71_FELCA ------------------------------------------------------------ B0CM67_PAPAN B0CM67_PAPAN ------------------------------------------------------------ A5HBC6_HUMAN A5HBC6_HUMAN ------------------------------------------------------------ A5HBC8_HUMAN A5HBC8_HUMAN ------------------------------------------------------------ A5HBC7_HUMAN A5HBC7_HUMAN ------------------------------------------------------------ A5HBD0_HUMAN A5HBD0_HUMAN ------------------------------------------------------------ A5HBD1_HUMAN A5HBD1_HUMAN ------------------------------------------------------------ Q9BUF0_HUMAN Q9BUF0_HUMAN ------------------------------------------------------------ Q9UE24_HUMAN Q9UE24_HUMAN ------------------------------------------------------------ MEN1_HUMAN MEN1_HUMAN ------------------------------------------------------------ B1MTL6_CALMO B1MTL6_CALMO ------------------------------------------------------------ B0KWK5_CALJA B0KWK5_CALJA ------------------------------------------------------------ B1H1W4_XENLA B1H1W4_XENLA KGSSGGNTNQEGELSSVKVTSSTKENSKSAGGRESSEGRKDQDEGNEESANKNLNSRPVQ Q0IHQ0_XENTR Q0IHQ0_XENTR KGGSGGHTKKEGEVSSVEITSSTKENSKS--GRECSEEKRDKDEGNEDSTNKNLHSKAAQ MATCH CONSENSUS ????????????????????????????????????????????????????????????

Q4T280_TETNG Q4T280_TETNG ------RFEP-LVPDCPN--------SCFPTVELGMISALYERFTAQIRGAVDLSEYRRT Q9PU64_DANRE Q9PU64_DANRE ------RFEP-LQPDSLN--------SCFPTVELNLLSALYERFMAQIRGAVDMSQYRKP Q503J8_DANRE Q503J8_DANRE ------RFEP-LQPDSLN--------SCFPTVELNLLSALYERFMAQIRGAVDMSQYRKP Q804R6_DANRE Q804R6_DANRE ------RFEP-LQPDSLN--------SCFPTVELNLLSALYERFMAQIRGAVDMSQYRKP Q5VSN4_DANRE Q5VSN4_DANRE ------RFEP-LQPDSLN--------SCFPTVELNLLSALYERFMAQIRGAVDMSQYRKP Q9IAA9_DANRE Q9IAA9_DANRE ------RFEP-LQPDSLN--------SCFPTVELNLLSALYERFMAQIRGAVDMSQYRKP B2KIB7_RHIFE B2KIB7_RHIFE -----------PNPLPP------------------------------------------- B3RF41_SORAR B3RF41_SORAR ------TFQPSPAPDPPG------GLTYFPVADLSIIAALYARFTAQIRGAVDLSLYPRE A5HBC9_HUMAN A5HBC9_HUMAN ------TFQPSPAPDPPG------GLTYFPVADLSIIAALYARFTAQIRGAVDLSLYPRE B5SNL0_OTOGA B5SNL0_OTOGA ------TFQPSPAPDPPG------GLTYFPVADLSIIAALYARFTAQIRGAVDLSLYPRE Q9WVR8_RAT Q9WVR8_RAT ------TFQPSPAPDPPG------GLTYFPVADLSIIAALYARFTAQIRGAVDLSLYPRE Q5NDM1_PRANA Q5NDM1_PRANA ------TFQPSPAPDPPG------GLTYFPVADLSIIAALYARFTAQIRGAVDLSLYPRE MEN1_MOUSE MEN1_MOUSE ------TFQPSPAPDPPG------GLTYFPVADLSIIAALYARFTAQIRGAVDLSLYPRE Q8CI72_MOUSE Q8CI72_MOUSE ------TFQPSPAPDPPG------GLTYFPVADLSIIAALYARFTAQIRGAVDLSLYPRE Q3U491_MOUSE Q3U491_MOUSE ------TFQPSPAPDPPG------GLTYFPVADLSIIAALYARFTAQIRGAVDLSLYPRE Q91UZ7_MOUSE Q91UZ7_MOUSE ------TFQPSPAPDPPG------GLTYFPVADLSIIAALYARFTAQIRGAVDLSLYPRE Q0P5I0_BOVIN Q0P5I0_BOVIN ------TFQPSPAPDPPG------GLTYFPVADLSIIAALYARFTAQIRGAVDLSLYPRE A2SXS5_CANFA A2SXS5_CANFA ------TFQPSPAPDPPG------GLTYFPVADLSIIAALYARFTAQIRGAVDLSLYPRE B5APJ3_MUSPF B5APJ3_MUSPF ------TFQPSPAPDPPG------GLTYFPVADLSIIAALYARFTAQIRGAVDLSLYPRE Q5GN71_FELCA Q5GN71_FELCA ------TFQPSPAPDPPG------GLTYFPVADLSIIAALYARFTAQIRGAVDLSLYPRE B0CM67_PAPAN B0CM67_PAPAN ------TFQPSPAPDPPG------GLTYFPVADLSIIAALYARFTAQIRGAVDLSLYPRE A5HBC6_HUMAN A5HBC6_HUMAN ------TFQPSPAPDPPG------GLTYFPVADLSIIAALYARFTAQIRGAVDLSLYPRE A5HBC8_HUMAN A5HBC8_HUMAN ------TFQPSPAPDPPG------GLTYFPVADLSIIAALYARFTAQIRGAVDLSLYPRE A5HBC7_HUMAN A5HBC7_HUMAN ------TFQPSPAPDPPG------GLTYFPVADLSIIAALYARFTAQIRGAVDLSLYPRE A5HBD0_HUMAN A5HBD0_HUMAN ------TFQPSPAPDPPG------GLTYFPVADLSIIAALYARFTAQIRGAVDLSLYPRE A5HBD1_HUMAN A5HBD1_HUMAN ------TFQPSPAPDPPG------GLTYFPVADLSIIA-------AQIRGAVDLSLYPRE Q9BUF0_HUMAN Q9BUF0_HUMAN ------------------------------------------------------------ Q9UE24_HUMAN Q9UE24_HUMAN ------------------------------------------------------------ MEN1_HUMAN MEN1_HUMAN ------TFQPSPAPDPPG------GLTYFPVADLSIIAALYARFTAQIRGAVDLSLYPRE B1MTL6_CALMO B1MTL6_CALMO ------TFQPSPTTDPPG------GLTYFPVADLSIIAALYARFTAQIRGAVDLSLYPRD B0KWK5_CALJA B0KWK5_CALJA ------TFQPSPTTDPPG------GLTYFPVADLSIIAALYARFTAQIRGAVDLSLYPRE B1H1W4_XENLA B1H1W4_XENLA KKEGKGPMKESPSNGTPKAESARSGIPYFPALELSVAQALHARFTAQTRGAVDLSCYPRE Q0IHQ0_XENTR Q0IHQ0_XENTR RKEAKGPVKEGPSNETSKAESARLGIPYFPALELSVAQALHARFTAQTRGAVDLSCYPRE MATCH CONSENSUS ???????F?P???PD?????????????FP???L????ALY?RF?AQIRGAVD?S?Y???

Q4T280_TETNG Q4T280_TETNG AEGSSRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSLIT-----GTKLDSSGVAFAVVAA Q9PU64_DANRE Q9PU64_DANRE SGASSRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSLIT-----GTKLDSSGVAFAVVAA Q503J8_DANRE Q503J8_DANRE SGASSRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSLIT-----GTKLDSSGVAFAVVAA Q804R6_DANRE Q804R6_DANRE SGASSRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSLIT-----GTKLDSSGVAFAVVAA Q5VSN4_DANRE Q5VSN4_DANRE SGASSRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSLIT-----GTKLDSSGVAFAVVAA Q9IAA9_DANRE Q9IAA9_DANRE SGASSRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSLIT-----GTKLDSSGVAFAVVAA B2KIB7_RHIFE B2KIB7_RHIFE --------------------------------------------GTKLDSSGVAFAVVGA B3RF41_SORAR B3RF41_SORAR GGVSSRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFIT-----GTKLDSSGVAFAVVGA A5HBC9_HUMAN A5HBC9_HUMAN GGVSSRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFIT-----GTKLDSSGVAFAVVGA B5SNL0_OTOGA B5SNL0_OTOGA GGVSSRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFITGWSPTGTKLDSSGVAFAVVGA Q9WVR8_RAT Q9WVR8_RAT GGVSSRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFIT-----GTKLDSSGVAFAVVGA Q5NDM1_PRANA Q5NDM1_PRANA GGVSSRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFIT-----GTKLDSSGVAFAVVGA MEN1_MOUSE MEN1_MOUSE GGVSSRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFIT-----GTKLDSSGVAFAVVGA Q8CI72_MOUSE Q8CI72_MOUSE GGVSSRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFIT-----GTKLDSSGVAFAVVGA Q3U491_MOUSE Q3U491_MOUSE GGVSSRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFIT-----GTKLDSSGVAFAVVGA Q91UZ7_MOUSE Q91UZ7_MOUSE GGVSSRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFIT-----GTKLDSSGVAFAVVGA Q0P5I0_BOVIN Q0P5I0_BOVIN GGVSSRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFIT-----GTKLDSSGVAFAVVGA A2SXS5_CANFA A2SXS5_CANFA GGVSSRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFITGWSPTGTKLDSSGVAFAVVGA B5APJ3_MUSPF B5APJ3_MUSPF GGVSSRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFITGWSLTGTKLDSSGVAFAVVGA Q5GN71_FELCA Q5GN71_FELCA GGVSSRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFIT-----GTKLDSSGVAFAVVGA B0CM67_PAPAN B0CM67_PAPAN GGVSSRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFITGWSPLGTKLDSSGVAFAVVGA A5HBC6_HUMAN A5HBC6_HUMAN GGVSSRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFIT-----GTKLDSSGVAFAVVGA A5HBC8_HUMAN A5HBC8_HUMAN GGVSSRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFIT-----GTKLDSSGVAFAVVGA A5HBC7_HUMAN A5HBC7_HUMAN GGVSSRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFIT-----GTKLDSSGVAFAVVGA A5HBD0_HUMAN A5HBD0_HUMAN GGVSSRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFFT-----GTKLDSSGVAFAVVGA A5HBD1_HUMAN A5HBD1_HUMAN GGVSSRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFIT-----GTKLDSSGVAFAVVGA Q9BUF0_HUMAN Q9BUF0_HUMAN ------------------------------------------------------------ Q9UE24_HUMAN Q9UE24_HUMAN ------------------------------------------------------------ MEN1_HUMAN MEN1_HUMAN GGVSSRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFITGWSPVGTKLDSSGVAFAVVGA B1MTL6_CALMO B1MTL6_CALMO GGVSSRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFITGWSPVGTKLDSSGVAFAVVGA B0KWK5_CALJA B0KWK5_CALJA GGVSSRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFIT-----GTKLDSSGVAFAVVGA B1H1W4_XENLA B1H1W4_XENLA DAVSGRELIRRVSDVIWNGLSRSYFKDRAHIQSLFSFVT-----GTKLDSPGVAFAVVAA Q0IHQ0_XENTR Q0IHQ0_XENTR DGVSGRELIRRVSDVIWNGLSRSYFKDRAHIQSLFSFVT-----GTKLDSPGVAFAVVAA MATCH CONSENSUS ?G?SSRELVKKVSDVIWNSLSRSYFKDRAHIQSLFS?IT?????GTKLDSSGVAFAVV?A

Q4T280_TETNG Q4T280_TETNG CQVLGLKDVHLALSEDHAWVIFGKNGEETAEVTWHGKGNEDRRGQTVAAGVSEKSWLYLK Q9PU64_DANRE Q9PU64_DANRE CQVLGLKDVHLALSEDHAWVIFGKGGEETAEVTWHGKGNEDRRGQTVSAGINERSWLYLK Q503J8_DANRE Q503J8_DANRE CQVLGLKDVHLALSEDHAWVIFGKGGEETAEVTWHGKGNEDRRGQTVSAGINERSWLYLK Q804R6_DANRE Q804R6_DANRE CQVLGLKDVHLALSEDHAWVIFGKGGEETAEVTWHGKGNEDRRGQTVSAGINERSWLYLK Q5VSN4_DANRE Q5VSN4_DANRE CQVLGLKDVHLALSEDHAWVIFGKGGEETAEVTWHGKGNEDRRGQTVSAGINERSWLYLK Q9IAA9_DANRE Q9IAA9_DANRE CQVLGLKDVHLALSEDHAWVIFGKGGEETAEVTWHGKGNEDRRGQTVSAGINERSWLYLK B2KIB7_RHIFE B2KIB7_RHIFE CQALGLRDVHLALSEDHAWVVFGPNGEQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLK B3RF41_SORAR B3RF41_SORAR CQALGLRDVHLALSEDHAWVVFGPNGEQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLK A5HBC9_HUMAN A5HBC9_HUMAN CQALGLRDVHLALSEDHAWVVFGPNGEQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLK B5SNL0_OTOGA B5SNL0_OTOGA CQALGLRDVHLALSEDHAWVVFGPNGEQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLK Q9WVR8_RAT Q9WVR8_RAT CQALGLRDVHLALSEDHAWVVFGSNGEQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLK Q5NDM1_PRANA Q5NDM1_PRANA CQALGLRDVHLALSEDHAWVVFGPNGEQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLK MEN1_MOUSE MEN1_MOUSE CQALGLRDVHLALSEDHAWVVFGPNGEQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLK Q8CI72_MOUSE Q8CI72_MOUSE CQALGLRDVHLALSEDHAWVVFGPNGEQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLK Q3U491_MOUSE Q3U491_MOUSE CQALGLRDVHLALSEDHAWVVFGPNGEQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLK Q91UZ7_MOUSE Q91UZ7_MOUSE CQALGLRDVHLALSEDHAWVVFGPNGEQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLK Q0P5I0_BOVIN Q0P5I0_BOVIN CQALGLRDVHLALSEDHAWVVFGPNGEQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLK A2SXS5_CANFA A2SXS5_CANFA CQALGLRDVHLALSEDHAWVVFGPNGEQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLK B5APJ3_MUSPF B5APJ3_MUSPF CQALGLRDVHLALSEDHAWVVFGPNGEQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLK Q5GN71_FELCA Q5GN71_FELCA CQALGLRDVHLALSEDHAWVVFGPNGEQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLK B0CM67_PAPAN B0CM67_PAPAN CQALGLRDVHLALSEDHAWVVFGPNGEQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLK A5HBC6_HUMAN A5HBC6_HUMAN CQALGLRDVHLALSEDHAWVVFGPNGEQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLK A5HBC8_HUMAN A5HBC8_HUMAN CQALGLRDVHLALSEDHAWVVFGPNGEQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLK A5HBC7_HUMAN A5HBC7_HUMAN CQALGLRDVHLALSEDHAWVVFGPNGEQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLK A5HBD0_HUMAN A5HBD0_HUMAN CQALGLRDVHLALSEDHAWVVFGPNGEQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLK A5HBD1_HUMAN A5HBD1_HUMAN CQALGLRDVHLALSEDHAWVVFGPNGEQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLK Q9BUF0_HUMAN Q9BUF0_HUMAN ------------------------------------------------------------ Q9UE24_HUMAN Q9UE24_HUMAN ------------------------------------------------------------ MEN1_HUMAN MEN1_HUMAN CQALGLRDVHLALSEDHAWVVFGPNGEQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLK B1MTL6_CALMO B1MTL6_CALMO CQALGLRDVHLALSEDHAWVVFGPNGEQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLK B0KWK5_CALJA B0KWK5_CALJA CQALGLRDVHLALSEDHAWVVFGPNGEQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLK B1H1W4_XENLA B1H1W4_XENLA CQVLGLSDVHLALSEDHAWVVFGKDGEQTAEVTWHGKGNEDRRGQSVSSGVLEKSWLYLN Q0IHQ0_XENTR Q0IHQ0_XENTR CQVLGLSDVHLALSEDHAWVVFGKDGEQTAEVTWHGKGNEDRRGQSVSSGVLEKSWLYLN MATCH CONSENSUS CQ?LGL?DVHLALSEDHAWV?FG??GE?TAEVTWHGKGNEDRRGQTV?AG??ERSWLYLK

Q4T280_TETNG Q4T280_TETNG GSYMKCDRNMEVAFMVCAINPSLDLHTDSSELLQLQQKLLWLLHDRGDLDRYPMALGTLA Q9PU64_DANRE Q9PU64_DANRE GSYMKCNRNMEVAFMVCAINPSLDLHTDSTELIQLQQRLLWLLYDRGDLERYPMAMGTLA Q503J8_DANRE Q503J8_DANRE GSYMKCNRNMEVAFMVCAINPSLDLHTDSTELIQLQQRLLWLLYDRGDLERYPMAMGTLA Q804R6_DANRE Q804R6_DANRE GSYMKCNRNMEVAFMVCAINPSLDLHTDSTELIQLQQRLLWLLYDRGDLERYPMAMGTLA Q5VSN4_DANRE Q5VSN4_DANRE GSYMKCNRNMEVAFMVCAINPSLDLHTDSTELIQLQQRLLWLLYDRGDLERYPMAMGTLA Q9IAA9_DANRE Q9IAA9_DANRE GSYMKCNRNMEVAFMVCAINPSLDLHTDSTELIQLQQRLLWLLYDRGDLERYPMAMGTLA B2KIB7_RHIFE B2KIB7_RHIFE GSYMRCDRKMEVAFMVCAINPSIDLHTDSLELLQLQQKLLWLLYDLGHLERYPMALGNLA B3RF41_SORAR B3RF41_SORAR GSYMRCDRKMEVAFMVCAINPSIDLHTDSLELLQLQQKLLWLLHDLGHLERYPMALGNLA A5HBC9_HUMAN A5HBC9_HUMAN GSYMRCDRKMEVAFMVCAINPSIDLHTDSLELLQLQQKLLWLLYDLGHLERYPMALGNLA B5SNL0_OTOGA B5SNL0_OTOGA GSYMCCDRKMEVAFMVCAINPSIDLHTDSLELLQLQQKLLWLLYDLGHLERYPMALGNLA Q9WVR8_RAT Q9WVR8_RAT GSYMRCDRKMEVAFMVCAINPSIDLHTDSLELLQLQQKLLWLLYDLGHLERYPMALGNLA Q5NDM1_PRANA Q5NDM1_PRANA GSYMRCDRKMEVAFMVCAINPSIDLHTDSLELLQLQQKLLWLLYDLGHLERYPMALGNLA MEN1_MOUSE MEN1_MOUSE GSYMRCDRKMEVAFMVCAINPSIDLHTDSLELLQLQQKLLWLLYDLGHLERYPMALGNLA Q8CI72_MOUSE Q8CI72_MOUSE GSYMRCDRKMEVAFMVCAINPSIDLHTDSLELLQLQQKLLWLLYDLGHLERYPMALGNLA Q3U491_MOUSE Q3U491_MOUSE GSYMRCDRKMEVAFMVCAINPSIDLHTDSLELLQLQQKLLWLLYDLGHLERYPMALGNLA Q91UZ7_MOUSE Q91UZ7_MOUSE GSYMRCDRKMEVAFMVCAINPSIDLHTDSLELLQLQQKLLWLLYDLGHLERYPMALGNLA Q0P5I0_BOVIN Q0P5I0_BOVIN GSYMRCDRKMEVAFMVCAINPSIDLHTDSLELLQLQQKLLWLLYDLGHLERYPMALGNLA A2SXS5_CANFA A2SXS5_CANFA GSYMRCDRKMEVAFMVCAINPSIDLHTDSLELLQLQQKLLWLLYDLGHLERYPMALGNLA B5APJ3_MUSPF B5APJ3_MUSPF GSYLRCDRKMEVAFMVCAINPSIDLHTDSLELLQLQQKLLWLLYDLGHLERYPMALGNLA Q5GN71_FELCA Q5GN71_FELCA GSYMRCDRKMEVAFMVCAINPSIDLHTDSLELLQLQQKLLWLLYDLGHLERYPMALGNLA B0CM67_PAPAN B0CM67_PAPAN GSYMRCDRKMEVAFMVCAINPSIDLHTDSLELLQLQQKLLWLLYDLGHLERYPMALGNLA A5HBC6_HUMAN A5HBC6_HUMAN GSYMRCDRKMEVAFMVCAINPSIDLHTDSLELLQLQQKLLWLLYDLGHLERYPMALGNLA A5HBC8_HUMAN A5HBC8_HUMAN GSYMRCDRKMEVAFMVCAINPSIDLHTDSLELLQLQQKLLWLLYDLGHLERYPMALGNLA A5HBC7_HUMAN A5HBC7_HUMAN GSYMRCDRKMEVAFMVCAINPSIDLHTDSLELLQLQQKLLWLLYDLGHLERYPMALGNLA A5HBD0_HUMAN A5HBD0_HUMAN GSYMRCDRKMEVAFMVCAINPSIDLHTDSLELLQLQQKLLWLLYDLGHLERYPMALGNLA A5HBD1_HUMAN A5HBD1_HUMAN GSYMRCDRKMEVAFMVCAINPSIDLHTDSLELLQLQQKLLWLLYDLGHLERYPMALGNLA Q9BUF0_HUMAN Q9BUF0_HUMAN ------------------------------------------------------------ Q9UE24_HUMAN Q9UE24_HUMAN ---------------------------------------------LGHLERYPMALGNLA MEN1_HUMAN MEN1_HUMAN GSYMRCDRKMEVAFMVCAINPSIDLHTDSLELLQLQQKLLWLLYDLGHLERYPMALGNLA B1MTL6_CALMO B1MTL6_CALMO GSYMRCDRKMEVAFMVCAINPSIDLHTDSLELLQLQQKLLWLLYDLGHLERYPMALGNLA B0KWK5_CALJA B0KWK5_CALJA GSYMRCDRKMEVAFMVCAINPSIDLHTDSLELLQLQQKLLWLLYDLGHLERYPMALGNLA B1H1W4_XENLA B1H1W4_XENLA GRYLRCDRHMEVAFMVCAINPSIDAHTDSLELLQLQQKLLWVLYDGGHLEKYPMALGNLA Q0IHQ0_XENTR Q0IHQ0_XENTR GRYLRCDRHMEVAFMVCAINPSIDAHTDSLELLQLQQKLLWVLFDGGHLDKYPMALGNLA MATCH CONSENSUS GSYM?C?R?MEVAFMVCAINPS?DLHTDS?EL?QLQQ?LLWLLYD?G?LERYPMALG?LA

Q4T280_TETNG Q4T280_TETNG DLEDQDPITGKETPLMIHLKAVSSAQRHYNNEHIYPYMYLAGFHYRHRNVQEALRAWAEA Q9PU64_DANRE Q9PU64_DANRE DLEDQEPMTGKESPLSIHLKAVESAKKYYNNEHIYPYMYLAGYHYRHREVREALGSWAEA Q503J8_DANRE Q503J8_DANRE DLEDQEPMTGKESPLSIHLKAVESAKKYYNNEHIYPYMYLAGYHYRHRDVREALGSWAEA Q804R6_DANRE Q804R6_DANRE DLEDQEPMTGKESPLSIHLKAVESAKKYYNNEHIYPYMYLAGYHYRHRDVREALGSWAEA Q5VSN4_DANRE Q5VSN4_DANRE DLEDQEPMTGKESPLSIHLKAVESAKKYYNNEHIYPYMYLAGYHYRHREVREALGSWAEA Q9IAA9_DANRE Q9IAA9_DANRE DLEDQEPMTGKESPLSIHLKAVESAKKYYNNEHIYPYMYLAGYHYRHREVREALGSWAEA B2KIB7_RHIFE B2KIB7_RHIFE DLEELEPTPGRPDPLTLYHKGIASAKTYYRDEHIYPYMYLAGYHCRNRNVREALQAWADT B3RF41_SORAR B3RF41_SORAR DLEELEPTPGRPDPLTLYHKGIASAKAYYRDEHIYPYMYLAGFHCRNRNVREALQAWADT A5HBC9_HUMAN A5HBC9_HUMAN DLEELEPTPGRPDPLTLYHKGIASAKTYYRDEHIYPYMYLAGYHCRNRNVREALQAWADT B5SNL0_OTOGA B5SNL0_OTOGA DLEELEPTPGRPDPLTLYHKGIASAKTYYRDEHIYPYMYLAGYHCRNRNVREALQAWADT Q9WVR8_RAT Q9WVR8_RAT DLEELEPTPGRPDPLTLYHKGIASAKTYYQDEHIYPYMYLAGYHCRNRNVREALQAWADT Q5NDM1_PRANA Q5NDM1_PRANA DLEELEPTPGRPDPLTLYHKGIASAKTYYQDEHIYPYMYLAGYHCRNRNVREALQAWADT MEN1_MOUSE MEN1_MOUSE DLEELEPTPGRPDPLTLYHKGIASAKTYYQDEHIYPYMYLAGYHCRNRNVREALQAWADT Q8CI72_MOUSE Q8CI72_MOUSE DLEELEPTPGRPDPLTLYHKGIASAKTYYQDEHIYPYMYLAGYHCRNRNVREALQAWADT Q3U491_MOUSE Q3U491_MOUSE DLEELEPTPGRPDPLTLYHKGIASAKTYYQDEHIYPYMYLAGYHCRNRNVREALQAWADT Q91UZ7_MOUSE Q91UZ7_MOUSE DLEELEPTPGRPDPLTLYHKGIASAKTYYQDEHIYPYMYLAGYHCRNRNVREALQAWADT Q0P5I0_BOVIN Q0P5I0_BOVIN DLEELEPTPGRPDPLTLYHKGIASAKTYYRDEHIYPYMYLAGYHCRNRNVREALQAWADT A2SXS5_CANFA A2SXS5_CANFA DLEELEPTPGRPDPLTLYHKGIASAKTYYRDEHIYPYMYLAGYHCRNRNVREALQAWADT B5APJ3_MUSPF B5APJ3_MUSPF DLEELEPTPGRPDPLTLYHKGIASAKTYYRDEHIYPYMYLAGYHCRNRNVREALQAWADT Q5GN71_FELCA Q5GN71_FELCA DLEELEPTPGRPDPXTLYHKGIASAKTYYRDEHIYPYMYLAGYHCRNRNVREALQAWADT B0CM67_PAPAN B0CM67_PAPAN DLEELEPTPGRPDPLTLYHKGIASAKTYYRDEHIYPYMYLAGYHCRNRNVREALQAWADT A5HBC6_HUMAN A5HBC6_HUMAN DLEELEPTPGRPDPLTLYHKGIASAKTYYRDEHIYPYMYLAGYHCRNRNVREALQAWADT A5HBC8_HUMAN A5HBC8_HUMAN DLEELEPTPGRPDPLTLYHKGIASAKTYYRDEHIYPYMYLAGYHCRNRNVREALQAWADT A5HBC7_HUMAN A5HBC7_HUMAN DLEELEPTPGRPDPLTLYHKGIASAKTYYRDEHIYPYMYLAGYHCRNRNVREALQAWADT A5HBD0_HUMAN A5HBD0_HUMAN DLEELEPTPGRPDPLTLYHKGIASAKTYYRDEHIYPYMYLAGYHCRNRNVREALQAWADT A5HBD1_HUMAN A5HBD1_HUMAN DLEELEPTPGRPDPLTLYHKGIASAKTYYRDEHIYPYMYLAGYHCRNRNVREALQAWADT Q9BUF0_HUMAN Q9BUF0_HUMAN -------------------------------------------HCRNRNVREALQAWADT Q9UE24_HUMAN Q9UE24_HUMAN DLEELEPTPGRPDPLTLYHKGIASAKTYYRDEHIYPYMYLAGYHCRNRNVREALQAWADT MEN1_HUMAN MEN1_HUMAN DLEELEPTPGRPDPLTLYHKGIASAKTYYRDEHIYPYMYLAGYHCRNRNVREALQAWADT B1MTL6_CALMO B1MTL6_CALMO DLEELERTPGRPDPLTLYHKGIASAKTYYRDEHIYPYMYLAGYHCRNRNVREALQAWADT B0KWK5_CALJA B0KWK5_CALJA DLEELERTPGRPDPLTLYHKGIASAKTYYRDEHIYPYMYLAGYHCRNRNVREALQAWADT B1H1W4_XENLA B1H1W4_XENLA DLEDLAATSGRPKPLEIYYKAVSSSCLHFENQHLYPHIYLAAYHCRNKDVREALKAWAET Q0IHQ0_XENTR Q0IHQ0_XENTR DLEDLAATHGRPNPLEIYHKAVSSSRLHYENQHLYPHIYLAAYHCRNKDIREALKAWAET MATCH * *:::::*** :**:: CONSENSUS DLE??EP??G???PL????K???SAK?YY??EHIYPYMYLAGYHCRNR?VREAL?AWA?T

Q4T280_TETNG Q4T280_TETNG AQVMQEYNYFREDEEIYKEFFDIANDVIPNLLKETTTGAENAGEG--ADKEQPKHASALS Q9PU64_DANRE Q9PU64_DANRE ASVMQDYNYCREDEEIYKEVFDIANDGIPTLLKETAAAAESEGTDEAEKEDQPREAAALT Q503J8_DANRE Q503J8_DANRE ASVMQDYNYCREDEEIYKEFFDIANDVIPTLLKETAAAAESEGTDEAEKEDQPREAAALT Q804R6_DANRE Q804R6_DANRE ASVMQDYNYCREDEEIYKEFFDIANDVIPTLLKETAAAAESEGTDEAEKEDQPREAAALT Q5VSN4_DANRE Q5VSN4_DANRE ASVMQDYNYCREDEEIYKEFFDIANDVIPTLLKETAAAAESEGTDEAEKEDQPREAAALT Q9IAA9_DANRE Q9IAA9_DANRE ASVMQDYNYCREDEEIYKEFFDIANDVIPTLLKETAAAAESEGTDEAEKEDQPREAAALT B2KIB7_RHIFE B2KIB7_RHIFE ATVIQDYNYCREDEEIYKEFFEVANDVIPNLLKEAASLLEA-GEERPGEQTQGPQSQG-S B3RF41_SORAR B3RF41_SORAR ATVIQDYNYCREDEEIYKEFFEVANDVIPNLLKEAASLLEA-GEER-AEQSQGPPGQG-S A5HBC9_HUMAN A5HBC9_HUMAN ATVIQDYNYCREDEEIYKEFFEVANDVIPNLLK---------GQ---------------- B5SNL0_OTOGA B5SNL0_OTOGA ATVIQDYNYCREDEEIYKEFFEVANDVIPNLLKEAASLLEA-GEERPGDQNQGSQSQG-S Q9WVR8_RAT Q9WVR8_RAT ATVIQDYNYCREDEEIYKEFFEVANDVIPNLLKEAASLLEA-GEERPGEQAQGTQGQG-S Q5NDM1_PRANA Q5NDM1_PRANA ATVIQDYNYCREDEEIYKEFFEVANDVIPNLLKEAASLLEA-GEERPGEQAQGTQGQG-S MEN1_MOUSE MEN1_MOUSE ATVIQDYNYCREDEEIYKEFFEVANDVIPNLLKEAASLLET-GEERTGEQAQGTQGQG-S Q8CI72_MOUSE Q8CI72_MOUSE ATVIQDYNYCREDEEIYKEFFEVANDVIPNLLKEAASLLET-GEERTGEQA--------- Q3U491_MOUSE Q3U491_MOUSE ATVIQDYNYCREDEEIYKEFFEVANDVIPNLLKEAASLLET-GEERTGEQAQGTQGQG-S Q91UZ7_MOUSE Q91UZ7_MOUSE ATVIQDYNYCREDEEIYKEFFEVANDVIPNLLKEAASLLET-GEERTGEQAQGTQGQG-S Q0P5I0_BOVIN Q0P5I0_BOVIN ATVIQDYNYCREDEEIYKEFFEVANDVIPNLLKEAASLLEA-GEERPGEQTQGTQSQG-S A2SXS5_CANFA A2SXS5_CANFA ATVIQDYNYCREDEEIYKEFFEVANDVIPNLLKEAASLLEA-GEERPGEQTQGVQSQG-S B5APJ3_MUSPF B5APJ3_MUSPF ATVIQDYNYCREDEEIYKEFFEVANDVIPNLLKEAASLLEA-GEERPGEQTQGAQSQG-S Q5GN71_FELCA Q5GN71_FELCA ATVIQDYNYCREDEEIYKEFFEVANDVIPNLLKEAASLLEA-GEERPGEQTQGAQSQS-S B0CM67_PAPAN B0CM67_PAPAN ATVIQDYNYCREDEEIYKEFFEVANDVIPNLLKEAASLLEA-GEERPGEQSQGTQSQG-S A5HBC6_HUMAN A5HBC6_HUMAN ATVIQDYNYCREDEEIYKEFFEVANDVIPNLLKEAASLLEA-GEERPGEQSQGTQSQG-S A5HBC8_HUMAN A5HBC8_HUMAN ATVIQDYNYCREDEEIYKEFFEVANDVIPNLLKEAASLLEA-GEERPGEQSQGTQSQG-S A5HBC7_HUMAN A5HBC7_HUMAN ATVIQDYNYCREDEEIYKEFFEVANDVIPNLLKEAASLLEA-GEERPGEQSQGTQSQG-S A5HBD0_HUMAN A5HBD0_HUMAN ATVIQDYNYCREDEEIYKEFFEVANDVIPNLLKEAASLLEA-GEERPGEQSQGTQSQG-S A5HBD1_HUMAN A5HBD1_HUMAN ATVIQDYNYCREDEEIYKEFFEVANDVIPNLLKEAASLLEA-GEERPGEQSQGTQSQG-S Q9BUF0_HUMAN Q9BUF0_HUMAN ATVIQDYNYCREDEEIYKEFFEVANDVIPNLLKEAASLLEA-GEERPGEQSQGTQSQG-S Q9UE24_HUMAN Q9UE24_HUMAN ATVIQDYNYCREDEEIYKEFFEVANDVIPNLLKEAASLLEA-GEERPGEQSQGTQSQG-S MEN1_HUMAN MEN1_HUMAN ATVIQDYNYCREDEEIYKEFFEVANDVIPNLLKEAASLLEA-GEERPGEQSQGTQSQG-S B1MTL6_CALMO B1MTL6_CALMO ATVIQDYNYCREDEEIYKEFFEVANDVIPNLLKEAASLLEA-GEERPGEQSQGTQSQG-S B0KWK5_CALJA B0KWK5_CALJA ATVIQDYNYCREDEEIYKEFFEVANDVIPNLLKEAASLLEA-GEERPGEQSQGTQSQG-S B1H1W4_XENLA B1H1W4_XENLA SAVVQSYNYCREDEEIYKDLFDIANDLLPNLLKEEAMSPDG--------------PSG-S Q0IHQ0_XENTR Q0IHQ0_XENTR SAVIQTYNYCREDEEIYKDLFDIANDLLPNLLKEEAM----------------------- MATCH : *:* *** ********:.*::*** :*.*** CONSENSUS A?V?QDYNYCREDEEIYKEFF??ANDVIPNLLKE?A???E??G????????Q????????

Q4T280_TETNG Q4T280_TETNG ALQDSECFAHLLRFYDGICKWEEGSPTPVLHVGWATYLVQSLSRFDAQVRQKVTIITKES Q9PU64_DANRE Q9PU64_DANRE ALQDPECFAHLLRFYDGICKWEEGSPTPVLHVGWATYLVQSLSRFDAQIRQKVSIITKDT Q503J8_DANRE Q503J8_DANRE ALQDPECFAHLLRFYDGICKWEEGSPTPVLHVGWATYLVQSLSRFDAQIRQKVSIITKDT Q804R6_DANRE Q804R6_DANRE ALQDPECFAHLLRFYDGICKWEEGSPTPVLHVGWATYLVQSLSRFDAQIRQKVSIITKDT Q5VSN4_DANRE Q5VSN4_DANRE ALQDPECFAHLLRFYDGICKWEEGSPTPVLHVGWATYLVQSLSRFDAQIRQKVSIITKDT Q9IAA9_DANRE Q9IAA9_DANRE ALQDPECFAHLLRFYDGICKWEEGSPTPVLHVGWATYLVQSLSRFDAQIRQKVSIITKDT B2KIB7_RHIFE B2KIB7_RHIFE ALQDPECFAHLLRFYDGICKWEEGSPTPVLHVGWATFLVQSLGRFEGQVRQKVRIVSRES B3RF41_SORAR B3RF41_SORAR ALQDPECFAHLLRFYDGICKWEEGSPTPVLHVGWATFLVQSLGRFEGQVRQKVRIVSREA A5HBC9_HUMAN A5HBC9_HUMAN ----PACWRR-------------------------------------------------- B5SNL0_OTOGA B5SNL0_OTOGA ALQDPECFAHLLRFYDGICKWEEGSPTPVLHVGWATFLVQSLGRFEGQVRQKVRIVSREA Q9WVR8_RAT Q9WVR8_RAT ALQDPECFAHLLRFYDGICKWEEGSPTPVLHVGWATFLVQSLGRFEGQVRQKVHIVSREA Q5NDM1_PRANA Q5NDM1_PRANA ALQDPECFAHLLRFYDGICKWEEGSPTPVLHVGWATFLVQSLGRFEGQVRQKVHIVSREA MEN1_MOUSE MEN1_MOUSE ALQDPECFAHLLRFYDGICKWEEGSPTPVLHVGWATFLVQSLGRFEGQVRQKVHMVSREA Q8CI72_MOUSE Q8CI72_MOUSE -----------------------------------------------QVRQKVHIVSREA Q3U491_MOUSE Q3U491_MOUSE ALQDPECFAHLLRFYDGICKWEEGSPTPVLHVGWATFLVQSLGRFEGQVRQKVHIVSREA Q91UZ7_MOUSE Q91UZ7_MOUSE ALQDPECFAHLLRFYDGICKWEEGSPTPVLHVGWATFLVQSLGRFEGQVRQKVHIVSREA Q0P5I0_BOVIN Q0P5I0_BOVIN ALQDPECFAHLLRFYDGICKWEEGSPTPVLHVGWATFLVQSLGRFEGQVRQKVRIVSREA A2SXS5_CANFA A2SXS5_CANFA ALQDPECFAHLLRFYDGICKWEEGSPTPVLHVGWATFLVQSLGRFEGQVRQKVRIVSREA B5APJ3_MUSPF B5APJ3_MUSPF ALQDPECFAHLLRFYDGICKWEEGSPTPVLHVGWATFLVQSLGRFEGQVRQKVRIVSREA Q5GN71_FELCA Q5GN71_FELCA ALQDPECFAHLLRFYDGICKWV-------------------------------------- B0CM67_PAPAN B0CM67_PAPAN ALQDPECFAHLLRFYDGICKWEEGSPTPVLHVGWATFLVQSLGRFEGQVRQKVRIVSREA A5HBC6_HUMAN A5HBC6_HUMAN ALQDPECFAHLLRFYDGICKWEEGSPTPVLHVGWATFLVQSLGRFEGQVRQKVRIVSREA A5HBC8_HUMAN A5HBC8_HUMAN ALQDPECFAHRLRFYDGICKWEEGSPTPVLHVGWATFLVQSLGRFEGQVRQKVRIVSREA A5HBC7_HUMAN A5HBC7_HUMAN ALQDPECFAHLPRFYDGICKWEEGSPTPVLHVGWATFLVQSLGRFEGQVRQKVRIVSREA A5HBD0_HUMAN A5HBD0_HUMAN ALQDPECFAHLLRFYDGICKWEEGSPTPVLHVGWATFLVQSLGRFEGQVRQKVRIVSREA A5HBD1_HUMAN A5HBD1_HUMAN ALQDPECFAHLLRFYDGICKWEEGSPTPVLHVGWATFLVQSLGRFEGQVRQKVRIVSREA Q9BUF0_HUMAN Q9BUF0_HUMAN ALQDPECFAHLLRFYDGICKWEEGSPTPVLHVGWATFLVQSLGRFEGQVRQKVRIVSREA Q9UE24_HUMAN Q9UE24_HUMAN ALQDPECFAHLLRFYDGICKWEEGSPTPVLHVGWATFLVQSLGRFEGQVRQKVRIVSREA MEN1_HUMAN MEN1_HUMAN ALQDPECFAHLLRFYDGICKWEEGSPTPVLHVGWATFLVQSLGRFEGQVRQKVRIVSREA B1MTL6_CALMO B1MTL6_CALMO ALQDPECFAHLLRFYDGICKWEEGSPTPVLHVGWATFLVQSLGRFEGQVRQKVRIVSREA B0KWK5_CALJA B0KWK5_CALJA ALQDPECFAHLLRFYDGICKWEEGSPTPVLHVGWATFLVQSLGRFEGQVRQKVRIVSREA B1H1W4_XENLA B1H1W4_XENLA ALQDPLCFANLLRFYDGICKWEEDSPTPVLHVGWATFLVQSLGRFDAQVRQQVTLLSSDS Q0IHQ0_XENTR Q0IHQ0_XENTR ------------------------------------------------------------ MATCH CONSENSUS ALQDPECFAHLLRFYDGICKWEEGSPTPVLHVGWAT?LVQSL?RF??Q?RQKV?I?????

Q4T280_TETNG Q4T280_TETNG EVQDDDDQSSDDPREGRRRCPRREYKADEQSSPLTLATSPSAQGPPAITQAKKVGEGGLR Q9PU64_DANRE Q9PU64_DANRE EPVDDDDQSSEDLREGRRRGPRRESKLDEP-----AGSASPNPALPAQNQNPVPKKVGGE Q503J8_DANRE Q503J8_DANRE EPVDDDDQSSEDLREGRRRGPRRESKLDEP-----AGSASPNPALPAQNQNPVPKKVGGE Q804R6_DANRE Q804R6_DANRE EPVDDDDQSSEDLREGRRRGPRRESKLDEP-----AGSASPNPALPAQNQNPVPKKVGGE Q5VSN4_DANRE Q5VSN4_DANRE EPVDDDDQSSEDLREGRRRGPRRESKLDEP-----AGSASPNPALPAQNQNPVPKKVGGE Q9IAA9_DANRE Q9IAA9_DANRE EPVDDDDQSSEDLREGRRRGPRRESKLDEP-----AGSASPNPALPAQNQNPVPKKVGGE B2KIB7_RHIFE B2KIB7_RHIFE EAAEAEEPWGEEAREGRRRGPRRESKPEEP----------PPPKKPALDKGPGTGQGAIP B3RF41_SORAR B3RF41_SORAR DTAEAEEPWGEEAREGRRRGPRRESKPEEP----------PPPKKPALDKGPGPG--AAQ A5HBC9_HUMAN A5HBC9_HUMAN ---------ARSGRGSKARAPRAKV---------------PPSR-------------TLS B5SNL0_OTOGA B5SNL0_OTOGA EAAEAEEPWGEEAREGRRRGPRRESKPEEP----------PPPKKPALDKGPGAGQSAVS Q9WVR8_RAT Q9WVR8_RAT EAAEAEEPWGDEAREGRRRGPRRESKPEEP----------PPPKKPALDKGPGSGQSAGS Q5NDM1_PRANA Q5NDM1_PRANA EAAEAEEPWGDEAREGRRRGPRRESKPEEP----------PPPKKPALDKGPGSGQSAAS MEN1_MOUSE MEN1_MOUSE EAAGAEEPWGDEAREGRRRGPRRESKPEEP----------PPPKKPALDKGPGSGQSAGL Q8CI72_MOUSE Q8CI72_MOUSE EAAEAEEPWGDEAREGRRRGPRRESKPEEP----------PPPKKPALDKGPGSGQSAGL Q3U491_MOUSE Q3U491_MOUSE EAAEAEEPWGDEAREGRRRGPRRESKPEEP----------PPPKKPALDKGPGSGQSAGS Q91UZ7_MOUSE Q91UZ7_MOUSE EAAEAEEPWGDEAREGRRRGPRRESKPEEP----------PPPKKPALDKGPGSGQSAGS Q0P5I0_BOVIN Q0P5I0_BOVIN EAAEAEEPWGEEAREGRRRGPRRESKPEEP----------PPPKKPALDKGPGAGQGAVP A2SXS5_CANFA A2SXS5_CANFA EAAEAEELWGEEAREGRRRGPRRESKPEEP----------PPPKKPALDKGPGGGQGAMS B5APJ3_MUSPF B5APJ3_MUSPF EAAEAEELWGEEAREGRRRGPRRESKPEEP----------PPPKKPALDKVPGGGQGAMS Q5GN71_FELCA Q5GN71_FELCA ------------------------------------------------------------ B0CM67_PAPAN B0CM67_PAPAN EAAEAEEPWGEEAREGRRRGPRRESKPEEP----------PPPKKPALDKGLGASQGAVS A5HBC6_HUMAN A5HBC6_HUMAN EAAEAEEPCGEEAREGRRRGPRRESKPEEP----------PPPKKPALDKGLGTGQGAVS A5HBC8_HUMAN A5HBC8_HUMAN EAAEAEEPWGEEAREGRRRGPRRESKPEEP----------PPPKKPALDKGLGTGQGAVS A5HBC7_HUMAN A5HBC7_HUMAN EAAEAEEPWGEEAREGRRRGPRRESKPEEP----------PPPKKPALDKGLGTGQGAVS A5HBD0_HUMAN A5HBD0_HUMAN EAAEAEEPWGEEAREGRRRGPRRESKPEEP----------PPPKKPALDKGLGTGQGAVS A5HBD1_HUMAN A5HBD1_HUMAN EAAEAEEPWGEEAREGRRRGPRRESKPEEP----------PPPKKPALDKGLGTGQGAVS Q9BUF0_HUMAN Q9BUF0_HUMAN EAAEAEEPWGEEAREGRRRGPRRESKPEEP----------PPPKKPALDKGLGTGQGAVS Q9UE24_HUMAN Q9UE24_HUMAN EAAEAEEPWGEEAREGRRRGPRRESKPEEP----------PPPKKPALDKGLGTGQGAVS MEN1_HUMAN MEN1_HUMAN EAAEAEEPWGEEAREGRRRGPRRESKPEEP----------PPPKKPALDKGLGTGQGAVS B1MTL6_CALMO B1MTL6_CALMO EAAEAEEPWGEEAREGRRRGPRRESKPEEP----------PPPKKPALDKGPGASQGAVS B0KWK5_CALJA B0KWK5_CALJA EAAEAEEPWGEEAREGRRRGPRRESKPEEP----------PPPKKPALDK----GQGAVS B1H1W4_XENLA B1H1W4_XENLA SNED------DDSEDSRRRGPRRESKTEES-----------------------TQLSSHN Q0IHQ0_XENTR Q0IHQ0_XENTR ------------------------------------------------------------ MATCH CONSENSUS E????????????REGRRRGPRRESK??EP??????????P?P??PA?????????????

Q4T280_TETNG Q4T280_TETNG --RRASQGLWVG---DG-EEKPPSLSPDPASPPPPYQTGPTSAGPVVVFQSEKMKGMKEL Q9PU64_DANRE Q9PU64_DANRE GGRRRSSASTRGKEADG-KNEPSSPSPIPSPSQPP----AVQGGPVVVFHSEKMKGMKEL Q503J8_DANRE Q503J8_DANRE GGRRRSSASTRGKEADG-KNEPSSPSPIPSPSQPP----AVQGGPVVVFHSEKMKGMKEL Q804R6_DANRE Q804R6_DANRE GGRRRSSTSTRGKEADG-KNEPSSPSPIPSPSQPP----AVQGGPVVVFHSEKMKGMKEL Q5VSN4_DANRE Q5VSN4_DANRE GGRRRSSASTRGKEADG-KNEPSSPSPIPSPSQPP----AVQGGPVVVFHSEKMKGMKEL Q9IAA9_DANRE Q9IAA9_DANRE GGRRRSSASTRGKEADG-KNEPSSPSPIPSPSQPP----AVQGGPVVVFHSEKMKGMKEL B2KIB7_RHIFE B2KIB7_RHIFE GPPRKPSGTVPSTTRGP-DGGSAAPVPPPAASPPP-------EGPVLTFQSEKMKGMKEL B3RF41_SORAR B3RF41_SORAR GPPRKPPGTVPGPARGP-EGSGPAPAPAPSASPPP-------EGPVLTFQSEKMKGMKEL A5HBC9_HUMAN A5HBC9_HUMAN ASPTCCDSTTASA-----NGRRAVPRLCCTWAGPP------------------------- B5SNL0_OTOGA B5SNL0_OTOGA APQRKPSGTVSGAARGP-EVGSTTQVPAPAASPPP-------EGPVLTFQSEKMKGMKEL Q9WVR8_RAT Q9WVR8_RAT GPPRKTSGTVSGTARGT-EVSSAAQAPAPAASPPP-------EGPVLTFQSEKMKGMKEL Q5NDM1_PRANA Q5NDM1_PRANA GPPRKTSGTVPGTTRGP-EVSNAAQAPAPAASPPP-------EGPVLTFQSEK------- MEN1_MOUSE MEN1_MOUSE GPPRKTSGTVPGTTRGGQEVGNAAQAPAPAASPPP-------EGPVLTFQSEKMKGMKEL Q8CI72_MOUSE Q8CI72_MOUSE GPPRKTSGTVPGTTRGGQEVGNAAQAPAPAASPPP-------EGPVLTFQSEKMKGMKEL Q3U491_MOUSE Q3U491_MOUSE GPPRKTSGTVPGTTRGGQEVGNAAQAPAPAASPPP-------EGPVLTFQSEKMKGMKEL Q91UZ7_MOUSE Q91UZ7_MOUSE GPPRKTSGTVPGTTRGGQEVGNAAQAPAPAASPPP-------EGPVLTFQSEKMKGMKEL Q0P5I0_BOVIN Q0P5I0_BOVIN GPPRKPPGTVPGTARGA-EGGSAAPVPAPAASPPP-------EGPVLTFQSEKMKGMKEL A2SXS5_CANFA A2SXS5_CANFA GPPRKPPGTVPGTARGP-EGGSTAPAPAPAASPPP-------EGPVLTFQSEKMKGMKEL B5APJ3_MUSPF B5APJ3_MUSPF GPPRKPPGTVPGTARGP-EGGSTAPAPAPAASPPP-------EGPVLTFQSEKMKGMKEL Q5GN71_FELCA Q5GN71_FELCA ------------------------------------------------------------ B0CM67_PAPAN B0CM67_PAPAN GPPRKPPGTVPGTARGP-EGGSTAQVPAPAASPPP-------EGPVLTFQSEKMKGMKEL A5HBC6_HUMAN A5HBC6_HUMAN GPPRKPPGTVAGTARGP-EGGSTAQVPAPAASPPP-------EGPVLTFQSEKMKGMKEL A5HBC8_HUMAN A5HBC8_HUMAN GPPRKPPGTVAGTARGP-EGGSTAQVPAPAASPPP-------EGPVLTFQSEKMKGMKEL A5HBC7_HUMAN A5HBC7_HUMAN GPPRKPPGTVAGTARGP-EGGSTAQVPAPAASPPP-------EGPVLTFQSEKMKGMKEL A5HBD0_HUMAN A5HBD0_HUMAN GPPRKPPGTVAGTARGP-EGGSTAQVPAPAASPPP-------EGPVLTFQSEKMKGMKEL A5HBD1_HUMAN A5HBD1_HUMAN GPPRKPPGTVAGTARGP-EGGSTAQVPAPAASPPP-------EGPVLTFQSEKMKGMKEL Q9BUF0_HUMAN Q9BUF0_HUMAN GPPRKPPGTVAGTARGP-EGGSTAQVPAPAASPPP-------EGPVLTFQSEKMKGMKEL Q9UE24_HUMAN Q9UE24_HUMAN GPPRKPPGTVAGTARGP-EGGSTAQVPAPAASPPP-------EGPVLTFQSEKMKGMKEL MEN1_HUMAN MEN1_HUMAN GPPRKPPGTVAGTARGP-EGGSTAQVPAPAASPPP-------EGPVLTFQSEKMKGMKEL B1MTL6_CALMO B1MTL6_CALMO GPPRKPPGTVPGTARGP-EGGSMAQAPAPAASPLP-------EGPVLTFQSEKMKGMKEL B0KWK5_CALJA B0KWK5_CALJA GPPRKPPGTVPGTARGP-EGGSTAQAPAPAASPPL-------EGPVLTFQSEKMKGMKEL B1H1W4_XENLA B1H1W4_XENLA GPPQK----------GE-ESEYEQLL-------------------TLTFQSQKMKGMKEL Q0IHQ0_XENTR Q0IHQ0_XENTR ---------------------------------SP-------DGPVSSQ----------- MATCH CONSENSUS G??R???????G??????????????P?P??S?PP????????GPV??F?SEKMKGMKEL

Q4T280_TETNG Q4T280_TETNG LCAAKVNSSAIKLQLTAQSQVQMKRQKTTPVGDYSMAFMKRQRKSL Q9PU64_DANRE Q9PU64_DANRE LSAAKVNSSAIKLQLTAQSQVQMKRQKPTASGDYTLSFMKRPRKTL Q503J8_DANRE Q503J8_DANRE LSAAKVNSSAIKLQLTAQSQVQMKRQKPTASGDYTLSFMKRPRKTL Q804R6_DANRE Q804R6_DANRE LSAAKVNSSAIKLQLTAQSQVQMKRQKPTASGDYTLSFMKRPRKTL Q5VSN4_DANRE Q5VSN4_DANRE LSAAKVNSSAIKLQLTAQSQVQMKRQKPTASGDYTLSFMKRPRKTL Q9IAA9_DANRE Q9IAA9_DANRE LSAAKVNSSAIKLQLTAQSQVQMKRQKPTASGDYTLSFMKRPRKTL B2KIB7_RHIFE B2KIB7_RHIFE LVATKINSSAIKLQLTAQSQVQMKKQKVSTPSDYTLSFLKRQRKGL B3RF41_SORAR B3RF41_SORAR LVATKINSSAIKLQLTAQSQVQMKKQKVSTPSDYTLSFLKRQRKGL A5HBC9_HUMAN A5HBC9_HUMAN -------------------------------------FLCSP---- B5SNL0_OTOGA B5SNL0_OTOGA LVATKINSSAIKLQLTAQSQVQMKKQKVSTPSDYTLSFLKRQRKGL Q9WVR8_RAT Q9WVR8_RAT LVATKINSSAIKLQLTAQSQVQMKKQKVSTPSDYTLSFLKRQRKGL Q5NDM1_PRANA Q5NDM1_PRANA ---------------------------------------------- MEN1_MOUSE MEN1_MOUSE LVATKINSSAIKLQLTAQSQVQMKKQKVSTPSDYTLSFLKRQRKGL Q8CI72_MOUSE Q8CI72_MOUSE LVATKINSSAIKLQLTAQSQVQMKKQKVSTPSDYTLSFLKRQRKGL Q3U491_MOUSE Q3U491_MOUSE LVATKINSSAIKLQLTAQSQVQMKKQKVSTPSDYTLSFLKRQRKGL Q91UZ7_MOUSE Q91UZ7_MOUSE LVATKINSSAIKLQLTAQSQVQMKKQKVSTPSDYTLSFLKRQRKGL Q0P5I0_BOVIN Q0P5I0_BOVIN LVATKINSSAIKLQLTAQSQVQMKKQKVSTPSDYTLSFLKRQRKGL A2SXS5_CANFA A2SXS5_CANFA LVATKINSSAIKLQLTAQSQVQMKKQKVSTPSDYTLSFLKRQRKGL B5APJ3_MUSPF B5APJ3_MUSPF LVATKINSSAIKLQLTAQSQVQMKKQKVSTPSDYTLSFLKRQRKGL Q5GN71_FELCA Q5GN71_FELCA ---------------------------------------------- B0CM67_PAPAN B0CM67_PAPAN LVATKINSSAIKLQLTAQSQVQMKKQKVSTPSDYTLSFLKRQRKGL A5HBC6_HUMAN A5HBC6_HUMAN LVATKINSSAIKLQLTAQSQVQMKKQKVSTPSDYTLSFLKRQRKGL A5HBC8_HUMAN A5HBC8_HUMAN LVATKINSSAIKLQLTAQSQVQMKKQKVSTPSDYTLSFLKRQRKGL A5HBC7_HUMAN A5HBC7_HUMAN LVATKINSSAIKLQLTAQSQVQMKKQKVSTPSDYTLSFLKRQRKGL A5HBD0_HUMAN A5HBD0_HUMAN LVATKINSSAIKLQLTAQSQVQMKKQKVSTPSDYTLSFLKRQRKGL A5HBD1_HUMAN A5HBD1_HUMAN LVATKINSSAIKLQLTAQSQVQMKKQKVSTPSDYTLSFLKRQRKGL Q9BUF0_HUMAN Q9BUF0_HUMAN LVATKINSSAIKLQLTAQSQVQMKKQKVSTPSDYTLSFLKRQRKGL Q9UE24_HUMAN Q9UE24_HUMAN LVATKINSSAIKLQLTAQSQVQMKKQKVSTPSDYTLSFLKRQRKGL MEN1_HUMAN MEN1_HUMAN LVATKINSSAIKLQLTAQSQVQMKKQKVSTPSDYTLSFLKRQRKGL B1MTL6_CALMO B1MTL6_CALMO LVATKINSSAIKLQLTAQSQVQMKKQKVSTPSDYTLSFLKRQRKGL B0KWK5_CALJA B0KWK5_CALJA LVATKINSSAIKLQLTAQSQVQMKKQKVSTPSDYTLSFLKRQRKGL B1H1W4_XENLA B1H1W4_XENLA LVAAKVNSSAIKLQLTAQSQVQPKRARGSGARDYNLGYLKRQRKGV Q0IHQ0_XENTR Q0IHQ0_XENTR ---------------------------------------------- MATCH CONSENSUS L?A?K?NSSAIKLQLTAQSQVQMK?QK?????DYTLSF?KR?RK?L


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