Alignment of the gene Family HBG000407 of HOVERGEN

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Threshold: 50% 80% 100%
Size: Bigger Smaller Normal
Isoforms are ON
B7ZUY2_DANRE B7ZUY2_DANRE AKRKDT-RQKSDTKKPKQIANTKSASKT---QKAKENGMETK---KNLKNSKVA----SR Q1LVE4_DANRE Q1LVE4_DANRE AKRKDT-RQKSDTKKPKQIANTKSGSKT---QKAKENGMETK---KNLKNSKVA----SR Q4S7W5_TETNG Q4S7W5_TETNG AKRKECAGKKTDTKRLKRDLKAKKSGGN---LGAKNDQTDKD--ITEEEENIIRKVEPKP B1H3H0_XENTR B1H3H0_XENTR NDGKTVGKQTQDPPNLKIKTPVKKFSGS-KDAEESEDEWEDVEANNQPQTGKTKRTGSEN Q7TSZ1_MOUSE Q7TSZ1_MOUSE APKRTADGRRR---KRGQKTEDNKVARH---EESVADDFEDEKQ-KPRRKSSFPKVSQGK XPC_MOUSE XPC_MOUSE APKRTADGRRR---KRGQKTEDNKVARH---EESVADDFEDEKQ-KPRRKSSFPKVSQGK Q5RBA2_PONAB Q5RBA2_PONAB ARKRAAGREPRGREPRSQKSKAKSKARREEEEEEEEDAFEDE---KPPKKSLPSKVSQGK XPC_HUMAN XPC_HUMAN ARKRAAGGEPRGRELRSQKSKAKSKARR---EEEEEDAFEDE---KPPKKSLLSKVSQGK A8K146_HUMAN A8K146_HUMAN ARKRAAGGEPRGRELRSQKSKAKSKARR---EEEEEDAFEDE---KPPKKSLLSKVSQGK B4DIP3_HUMAN B4DIP3_HUMAN ARKRAAGGEPRGRELRSQKSKAKSKARR---EEEEEDAFEDE---KPPKKSLLSKVSQGK MATCH : . :. . : : . . . CONSENSUS A????????????????Q????K?????????????D??E?????K????S?????????

B7ZUY2_DANRE B7ZUY2_DANRE RSRKV-------------------------------------KDVFDEVTSKYFQDSEVK Q1LVE4_DANRE Q1LVE4_DANRE RSRKV-------------------------------------KDVLDEVTSKYFQDSEVK Q4S7W5_TETNG Q4S7W5_TETNG RRSKQ---------------PAVGNKTTTKT-----------KTTTDFQTSKYF-QSSVK B1H3H0_XENTR B1H3H0_XENTR SKAGVKKERRLSVKSNIRKRSRPGDLDDGEDGFKEESSVKKRKPTVPGVKGK---TKAAK Q7TSZ1_MOUSE Q7TSZ1_MOUSE RKRGC---------------SDPGDPTNGAA-----------KKKVAKATAK---SKNLK XPC_MOUSE XPC_MOUSE RKRGC---------------SDPGDPTNGAA-----------KKKVAKATAK---SKNLK Q5RBA2_PONAB Q5RBA2_PONAB RKRGC---------------SHPGRSADGPA-----------KKKVAKVTVK---SENLK XPC_HUMAN XPC_HUMAN RKRGC---------------SHPGGSADGPA-----------KKKVAKVTVK---SENLK A8K146_HUMAN A8K146_HUMAN RKRGC---------------SHPGGSADGPA-----------KKKVAKVTVK---SENLK B4DIP3_HUMAN B4DIP3_HUMAN RKRGC---------------SHPGGSADGPA-----------KKKVAKVTVK---SENLK MATCH * . * . * CONSENSUS R?R????????????????????G??????????????????K??????T?K???????K

B7ZUY2_DANRE B7ZUY2_DANRE TEEPEDLSDHSEERMIIEDISLS------------------------KQVKEEEEDSEDE Q1LVE4_DANRE Q1LVE4_DANRE TEEPEDLSDHSEERMIIEDTSLS------------------------KQVKEEEEDSEDE Q4S7W5_TETNG Q4S7W5_TETNG KEESDSEEDFDTGWSAAPPAGAN-------------------KKKVEKDAEGEQDSEEDE B1H3H0_XENTR B1H3H0_XENTR PAGNASCAGNQKPRAKKSAVREPKTQETEILDLLALEKKTPRKGATVKESSESEEAEDSD Q7TSZ1_MOUSE Q7TSZ1_MOUSE VLKEEALSDGDDFRDSPADCKKA---------------KKHPKSKVVDQGTDEDD---SE XPC_MOUSE XPC_MOUSE VLKEEALSDGDDFRDSPADCKKA---------------KKHPKSKVVDQGTDEDD---SE Q5RBA2_PONAB Q5RBA2_PONAB VIKDEALSDGDDLRDVPSDLKKA---------------HHPKRGATMNEDSNEEE-EESE XPC_HUMAN XPC_HUMAN VIKDEALSDGDDLRDFPSDLKKA---------------HHLKRGATMNEDSNEEE-EESE A8K146_HUMAN A8K146_HUMAN VIKDEALSDGDDLRDFPSDLKKA---------------HHLKRGATMNEDSNEEE-EESE B4DIP3_HUMAN B4DIP3_HUMAN VIKDEALSDGDDLRDFPSDLKKA---------------HHLKRGATMNEDSNEEE-EESE MATCH . . .: .:: .: CONSENSUS ????E?LSD????R????D?????????????????????????????????E??????E

B7ZUY2_DANRE B7ZUY2_DANRE DDWEEVEEMAGPL-----GPVDSSELALESKPVEIEIETPDMIRKRQKKEKRKAEFETYL Q1LVE4_DANRE Q1LVE4_DANRE DDWEEVEEMAGPL-----GPVDSSELALESKPVEIEIETPDMIRKRQKKEKRKAEFETYL Q4S7W5_TETNG Q4S7W5_TETNG DDWEEVEELSEPL-----GPVEAQEPALPSQSLEIEIETPEVRKER----KRQAEWETYV B1H3H0_XENTR B1H3H0_XENTR EEWEDVEELNGSVLDDL-QASTSADIPLPTQPVEIEIETAEAAKKRLRREKRKEEFAAYL Q7TSZ1_MOUSE Q7TSZ1_MOUSE DDWEEVEELTEPVL-DMGENSATSPSDMPVKAVEIEIETPQQAKERERSEKIKMEFETYL XPC_MOUSE XPC_MOUSE DDWEEVEELTEPVL-DMGENSATSPSDMPVKAVEIEIETPQQAKERERSEKIKMEFETYL Q5RBA2_PONAB Q5RBA2_PONAB NDWEEVEELTEPVLGDVRESTAFSRSLLPVKPVEIEIETPEQAKTRERSEKIKLEFETHL XPC_HUMAN XPC_HUMAN NDWEEVEELSEPVLGDVRESTAFSRSLLPVKPVEIEIETPEQAKTRERSEKIKLEFETYL A8K146_HUMAN A8K146_HUMAN NDWEEVEELSEPVLGDVRESTAFSRSLLPVKPVEIEIETPEQAKTRERSEKIKLEFETYL B4DIP3_HUMAN B4DIP3_HUMAN NDWE-------------------------------------QAKTRERSEKIKLEFETYL MATCH ::** : * * : *: ::: CONSENSUS ?DWEEVEE???P????????????????????VEIEIETP???K?R???EK?K?EFETYL

B7ZUY2_DANRE B7ZUY2_DANRE RRMMNRFNKDLLVDTHK------------VHLLCLMASGLFRNRLLCEPDLLAVALSLLP Q1LVE4_DANRE Q1LVE4_DANRE RRMMNRFNKDLLVDTHK------------VHLLCLMASGLFRNRLLCEPDLLAVALSLLP Q4S7W5_TETNG Q4S7W5_TETNG RRMVNRYKKDLLVDMHKVKTPTQTSAGLEVHLMCLIARGMFQNRLCSQPDLLAITLSLLP B1H3H0_XENTR B1H3H0_XENTR RRLMKK----VREDTHK------------VHLLCLLANGFYRSNTCNLPDLQAVALSVVP Q7TSZ1_MOUSE Q7TSZ1_MOUSE RRMMKRFNKEVQENMHK------------VHLLCLLASGFYRNSICRQPDLLAIGLSIIP XPC_MOUSE XPC_MOUSE RRMMKRFNKEVQENMHK------------VHLLCLLASGFYRNSICRQPDLLAIGLSIIP Q5RBA2_PONAB Q5RBA2_PONAB RRAMKRFNKEVHEDTHK------------VHLLCLLANGLYRNNICSQPDLHAIGLSIVP XPC_HUMAN XPC_HUMAN RRAMKRFNKGVHEDTHK------------VHLLCLLANGFYRNNICSQPDLHAIGLSIIP A8K146_HUMAN A8K146_HUMAN RRAMKRFNKGVHEDTHK------------VHLLCLLANGFYRNNICSQPDLHAIGLSIIP B4DIP3_HUMAN B4DIP3_HUMAN RRAMKRFNKGVHEDTHK------------VHLLCLLANGFYRNNICSQPDLHAIGLSIIP MATCH ** ::: : : ** ***:**:* *:::. *** *: **::* CONSENSUS RR?M?RFNK????D?HK????????????VHLLCL?A?G??RN??C??PDL?A??LS??P

B7ZUY2_DANRE B7ZUY2_DANRE AHFTAVSLKRINNGFLEGLLKW-----------------------FQATFTLNPALPEEK Q1LVE4_DANRE Q1LVE4_DANRE SHFTTVSLKRINNGFLEGLLKW-----------------------FQATFTLNPALPEEK Q4S7W5_TETNG Q4S7W5_TETNG THFSMVAKDRVDQNFLSGLLRWCVVVNSQTHGVCLTSPLWILPCRFRTTFTLNPSLPCER B1H3H0_XENTR B1H3H0_XENTR VKFTSVPADRVDVVYLTNLTKW-----------------------FRGTFTLSHEMSLDE Q7TSZ1_MOUSE Q7TSZ1_MOUSE IRFTKVPLQDRDAYYLSNLVKW-----------------------FIGTFTVNADLSASE XPC_MOUSE XPC_MOUSE IRFTKVPLQDRDAYYLSNLVKW-----------------------FIGTFTVNADLSASE Q5RBA2_PONAB Q5RBA2_PONAB ARFTRVLPRDVDTYYLSNLVKW-----------------------FIGTFTVNAELSASE XPC_HUMAN XPC_HUMAN ARFTRVLPRDVDTYYLSNLVKW-----------------------FIGTFTVNAELSASE A8K146_HUMAN A8K146_HUMAN ARFTRVLPRDVDTYYLSNLVKW-----------------------FIGTFTVNAELSASE B4DIP3_HUMAN B4DIP3_HUMAN ARFTRVLPRDVDTYYLSNLVKW-----------------------FIGTFTVNAELSASE MATCH :*: * : :* .* :* * ***:. :. .. CONSENSUS ??FT?V?????D???L??L?KW???????????????????????F??TFT?N??L????

B7ZUY2_DANRE B7ZUY2_DANRE EVDLRTVLEKRMGCLSARNHEEMTYLFLLVLRSLRLFCRLVLSLQPLPLKPPPATKSKT- Q1LVE4_DANRE Q1LVE4_DANRE EVDLRTVLEKRMGCLSARNHEEMTYLFLLVLRSLRLFCRLVLSLQPLPLKPPPATKSKT- Q4S7W5_TETNG Q4S7W5_TETNG RADPRLLLEGRLASLSARNHEEMTHLFLLVLRSLQLFCRLVLSLQPVPLKLPPAKVLTLV B1H3H0_XENTR B1H3H0_XENTR SESMSATLERRFGVYGVRDEAEMVHVFLILLRALQLLSRLVLSLQPIPLKDPPAKTKQP- Q7TSZ1_MOUSE Q7TSZ1_MOUSE QDDLQTTLERRIAIYSARDNEELVHIFLLILRALQLLTRLVLSLQPIPLKSAVTKGRKS- XPC_MOUSE XPC_MOUSE QDDLQTTLERRIAIYSARDNEELVHIFLLILRALQLLTRLVLSLQPIPLKSAVTKGRKS- Q5RBA2_PONAB Q5RBA2_PONAB QDNLQSTLERRFAIYSARDDEELVHIFLLILRALQLLTRLVLSLHPIPLKSATAKGKKP- XPC_HUMAN XPC_HUMAN QDNLQTTLERRFAIYSARDDEELVHIFLLILRALQLLTRLVLSLQPIPLKSATAKGKKP- A8K146_HUMAN A8K146_HUMAN QDNLQTTLERRFAIYSARDDEELVHIFLLILRALQLLTRLVLSLQPIPLKSATAKGKKP- B4DIP3_HUMAN B4DIP3_HUMAN QDNLQTTLERRFAIYSARDDEELVHIFLLILRALQLLTRLVLSLQPIPLKSATAKGKKP- MATCH . ** *:. ..*:. *:.::**::**:*:*: ******:*:*** . :. CONSENSUS ???L???LE?R????SAR??EE??H?FLL?LR?LQL??RLVLSLQP?PLK???AK??K??

B7ZUY2_DANRE B7ZUY2_DANRE ---------TPSKSSSEKAQSEKSSPELKV-SPGSKRP----------------SSATAA Q1LVE4_DANRE Q1LVE4_DANRE ---------TPSKSSSEKAQSEKSSPELKV-SPGSKRP----------------SSATAA Q4S7W5_TETNG Q4S7W5_TETNG VFSRLLIFVQQGKSAARTSEKSNANQEKRRCDPKQTGD----------------KRPINE B1H3H0_XENTR B1H3H0_XENTR --RKEKSSTRSSTKPQTAKGKSKSNNRKQVRQKKVKQEDSLSGESEEEEEYPVDCTTSGR Q7TSZ1_MOUSE Q7TSZ1_MOUSE --SKETSVEGPGGSSELSSNSPESHNKPTT-SRRIKEEETLSEGR---------GKATAR XPC_MOUSE XPC_MOUSE --SKETSVEGPGGSSELSSNSPESHNKPTT-SRRIKEEETLSEGR---------GKATAR Q5RBA2_PONAB Q5RBA2_PONAB --SKERLTADPGASSETSSQVLENHTKPKT-SKGTKQEETLAKGT---------CKPSAK XPC_HUMAN XPC_HUMAN --SKERLTADPGGSSETSSQVLENHTKPKT-SKGTKQEETFAKGT---------CRPSAK A8K146_HUMAN A8K146_HUMAN --SKERLTADPGGSSETSSQVLENHTKPKT-SKGTKQEETFAKGT---------CRPSAK B4DIP3_HUMAN B4DIP3_HUMAN --SKERLTADPGGSSETSSQVLENHTKPKT-SKGTKQEETFAKGT---------CRPSAK MATCH . .. : . . . . CONSENSUS ??????????P??SS????????????????S???K??????????????????????A?

B7ZUY2_DANRE B7ZUY2_DANRE AKEDRG--GKRKKKTG-------GGGDKEAAGAQK-PKNSRRRSVASKVSYKEVGSEEEE Q1LVE4_DANRE Q1LVE4_DANRE AKEDRG--GKRKKKTG-------GGGDKEAAGAQK-PKNSRRRSVASKVSYKEVGSEEEE Q4S7W5_TETNG Q4S7W5_TETNG GKSSGGRGGKKAKRVGAEKETEQREEEKSTPSAGQRPKNSTRRSIASKVSYKEESSSDGE B1H3H0_XENTR B1H3H0_XENTR GK------GKTTKGKKAVKS-----ADKEEACTGARPKNQLRRKAASKVTYKEESESCGH Q7TSZ1_MOUSE Q7TSZ1_MOUSE GKRGTGTAGSRQRRKPSCSE-----GEEAEQKVQGRPHARKRR-VAAKVSYKEESESDGA XPC_MOUSE XPC_MOUSE GKRGTGTAGSRQRRKPSCSE-----GEEAEQKVQGRPHARKRR-VAAKVSYKEESESDGA Q5RBA2_PONAB Q5RBA2_PONAB GKRNKG--GRKKRSKPSSSEEDEGPGDKQEKATQRRPHGRERR-VASRVSYKEESGSDEA XPC_HUMAN XPC_HUMAN GKRNKG--GRKKRSKPSSSEEDEGPGDKQEKATQRRPHGRERR-VASRVSYKEESGSDEA A8K146_HUMAN A8K146_HUMAN GKRNKG--GRKKRSKPSSSEEDEGPGDKQEKATQRRPHGRERR-VASRVSYKGESGSDEA B4DIP3_HUMAN B4DIP3_HUMAN GKRNKG--GRKKRSKPSSSEEDEGPGDKQEKATQRRPHGRERR-VASRVSYKEESGSDEA MATCH .* * : :: . *: ** *::*:** . . CONSENSUS GK???G??G????????????????G?K?????Q?RP????RR?VAS?VSYKEES?S???

B7ZUY2_DANRE B7ZUY2_DANRE EQ--SEEEFQPSNEDDS----EDSDGAVKICRKSKVKSRRSSKVKQEERSEEEEEEEEEE Q1LVE4_DANRE Q1LVE4_DANRE EQ--SEEEFQPSNEDDS----EDSDGAVKICRKSKVKSRRSSKVKQEERSEEEEEEEEEE Q4S7W5_TETNG Q4S7W5_TETNG EKAASDDDFQVSSEEEDGVDSENEAISTKRAGKRRSKQDSGGKRKQDSRELEEKEEMDEG B1H3H0_XENTR B1H3H0_XENTR S---SDSDFCLSASQDSDCSEWEEEPLDSKRRRSSGPVKEIIKKERNTNPVAKEQPRAKN Q7TSZ1_MOUSE Q7TSZ1_MOUSE G---SGSDFEPSSGEGQHSSDEDCEPGPRKQKRASAPQRTKAGSKSASKTQRGSQCDPSS XPC_MOUSE XPC_MOUSE G---SGSDFEPSSGEGQHSSDEDCEPGPRKQKRASAPQRTKAGSKSASKTQRGSQCEPSS Q5RBA2_PONAB Q5RBA2_PONAB G---SGSDFELSSGEASDPSDEDSEPGPPKQRKAPAPQRTKAGSKGASRTQRGSHHKDPS XPC_HUMAN XPC_HUMAN G---SGSDFELSSGEASDPSDEDSEPGPPKQRKAPAPQRTKAGSKSASRTHRGSHRKDPS A8K146_HUMAN A8K146_HUMAN G---SGSDFELSSGEASDPSDEDSEPGPPKQRKAPAPQRTKAGSKSASRTHRGSHRKDPS B4DIP3_HUMAN B4DIP3_HUMAN G---SGSDFELSSGEASDPSDEDSEPGPPKQRKAPAPQRTKAGSKSASRTHRESHRKDPS MATCH * .:* * : . : : : . .. CONSENSUS ????S??DF??S?????????ED???????????????R?????K???????????????

B7ZUY2_DANRE B7ZUY2_DANRE -----EEEKEVKKQRRKKKQG-----------------KGADEWLEVYLESSGRWVCVDV Q1LVE4_DANRE Q1LVE4_DANRE -----EEEKEVKKQRRKKKQG-----------------KGADEWLEVYLESSGRWVCVDV Q4S7W5_TETNG Q4S7W5_TETNG GGGGGGPGNGAKRRSGRKKEG-----------------LGDDEWLEVYLAKTSSWICVDV B1H3H0_XENTR B1H3H0_XENTR PTDSLSSTQPKRRGKIISTDESEMDDEGTMEKASVVSPIVCDQWVEVYLESERKWLCVDC Q7TSZ1_MOUSE Q7TSZ1_MOUSE FPEASSSSSGCKRGKKVSSGA---------EEMADRKPAGVDQWLEVYCEPQAKWVCVDC XPC_MOUSE XPC_MOUSE FPEASSSSSGCKRGKKVSSGA---------EEMADRKPAGVDQWLEVYCEPQAKWVCVDC Q5RBA2_PONAB Q5RBA2_PONAB LPAASSSSSSSKRGKKMSSDG---------ERAEKRSIAGVDQWLEVFCEQEEKWICVDC XPC_HUMAN XPC_HUMAN LPVASSSSSSSKRGKKMCSDG---------EKAEKRSIAGIDQWLEVFCEQEEKWVCVDC A8K146_HUMAN A8K146_HUMAN LPAASSSSSSSKRGKKMCSDG---------EKAEKRSIAGIDQWLEVFCEQEEKWVCVDC B4DIP3_HUMAN B4DIP3_HUMAN LPAASSSSSSSKRGKKMCSDG---------EKAEKRSIAGIDQWLEVFCEQEEKWVCVDC MATCH . :: . *:*:**: *:*** CONSENSUS ???????????KR??????????????????????????G?D?WLEV??E????W?CVD?

B7ZUY2_DANRE B7ZUY2_DANRE DQG-VGQPQLCSDQATLPITYVVGLDDEGFMKDLGSRYDPTWLTSSRRRRVDSEWWEETM Q1LVE4_DANRE Q1LVE4_DANRE DQG-VGQPQLCSDQATLPITYVVGLDDEGFMKDLGSRYDPTWLTSSRRRRVDSEWWEETM Q4S7W5_TETNG Q4S7W5_TETNG EQG-IGMPHLCSQKASSPVTYVVSVDGDGFVKDLGRKYDPTWMTLSRKRRVEEDWWEDTL B1H3H0_XENTR B1H3H0_XENTR VHWTVGKPQMCFNTATKPVTYVVGIDNAGCVKDVTRRYDVDWMTSTRKRRVEPDWWEETL Q7TSZ1_MOUSE Q7TSZ1_MOUSE VHGVVGQPVACYKYATKPMTYVVGIDSDGWVRDVTQRYDPAWMTATRKCRVDAEWWAETL XPC_MOUSE XPC_MOUSE VHGVVGQPVACYKYATKPMTYVVGIDSDGWVRDVTQRYDPAWMTATRKCRVDAEWWAETL Q5RBA2_PONAB Q5RBA2_PONAB VHGVVGQPLTCYKYATKPVTYVVGIDSDGWVRDVTQRYDPAWMTVTRKCRVDAEWWAETL XPC_HUMAN XPC_HUMAN VHGVVGQPLTCYKYATKPMTYVVGIDSDGWVRDVTQRYDPVWMTVTRKCRVDAEWWAETL A8K146_HUMAN A8K146_HUMAN VHGVVGQPLTCYKYATKPMTYVVGIDSDGWVRDVTQRYDPVWMTVTRKCRVDAEWWAETL B4DIP3_HUMAN B4DIP3_HUMAN VHGVVGQPLTCYKYATKPMTYVVGIDSDGWVRDVTQRYDPVWMTVTRKCRVDAEWWAETL MATCH : :* * * . *: *:****.:*. * ::*: :** *:* :*: **: :** :*: CONSENSUS ??G?VGQP??C???AT?P?TYVVG?D??G?V?D???RYDP?WMT??RK?RVD?EWW?ETL

B7ZUY2_DANRE B7ZUY2_DANRE ELYKSPDTERGQKEDQEMQAKLLDKPLPTSVSEYKNHPLYVLKRHLLKYEALYPATAAVL Q1LVE4_DANRE Q1LVE4_DANRE ELYKSPDTERGQKEDQEMQAKLLDKPLPTSVSEYKNHPLYVLKRHLLKYEALYPATAAVL Q4S7W5_TETNG Q4S7W5_TETNG APFMGPEDEKDQKEDKELQKTLLNKPLPISVAEYKNHPLYALKRHLLKYEAIYPSTAAVL B1H3H0_XENTR B1H3H0_XENTR MPYKNPDADREDREEVELEFKLLDQPLPTSITGYKDHPLYVLKRHLLKYEAIYPETAAIL Q7TSZ1_MOUSE Q7TSZ1_MOUSE RPYRSLLTEREKKEDQEFQAKHLDQPLPTSISTYKNHPLYALKRHLLKFQAIYPETAAVL XPC_MOUSE XPC_MOUSE RPYRSLLTEREKKEDQEFQAKHLDQPLPTSISTYKNHPLYALKRHLLKFQAIYPETAAVL Q5RBA2_PONAB Q5RBA2_PONAB RPYQSPFMDREKKEDLEFQAKHMDQPLPTAIGLYKNHPLYALKRHLLKYEAIYPETAAIL XPC_HUMAN XPC_HUMAN RPYQSPFMDREKKEDLEFQAKHMDQPLPTAIGLYKNHPLYALKRHLLKYEAIYPETAAIL A8K146_HUMAN A8K146_HUMAN RPYQSPFMDREKKEDLEFQAKHMDQPLPTAIGLYKNHPLYALKRHLLKYEAIYPETAAIL B4DIP3_HUMAN B4DIP3_HUMAN RPYQSPFMDREKKEDLEFQAKHMDQPLPTAIGLYKNHPLYALKRHLLKYEAIYPETAAIL MATCH : . :: .:*: *:: . :::*** :: **:****.*******::*:** ***:* CONSENSUS ?PY?SP???R??KED?E?QAK??D?PLPT????YKNHPLY?LKRHLLKYEAIYP?TAA?L

B7ZUY2_DANRE B7ZUY2_DANRE GYCRGEPVYSRDCVHTLHSRDTWLKEARTVRLGEEPYKMVLGFSNRSRKARMMSEQ-KNV Q1LVE4_DANRE Q1LVE4_DANRE GYCRGEPVYSRDCVHTLHSRDTWLKEARTVRLGEEPYKMVLGFSNRSRKARMMSEQ-KNV Q4S7W5_TETNG Q4S7W5_TETNG GYCRGEAVYSRDCVHTLHSRDTWLKEARTVGLGEEPYKMVKGFSNRSRKARMMSEL-KNE B1H3H0_XENTR B1H3H0_XENTR GYCRGEAVYSRSCVHTLHSSDTWLKEARVVRLAEVPYKMVKGYSNRARKARSSDPQKKDH Q7TSZ1_MOUSE Q7TSZ1_MOUSE GYCRGEAVYSRDCVHTLHSRDTWLKQARVVRLGEVPYKMVKGFSNRARKARLSEPQLHDH XPC_MOUSE XPC_MOUSE GYCRGEAVYSRDCVHTLHSRDTWLKQARVVRLGEVPYKMVKGFSNRARKARLSEPQLHDH Q5RBA2_PONAB Q5RBA2_PONAB GYCRGEAVYSRDCVHTLHSRDTWLKKARVVRLGEVPYKMVKGFSNRARKARLAEPQLREE XPC_HUMAN XPC_HUMAN GYCRGEAVYSRDCVHTLHSRDTWLKKARVVRLGEVPYKMVKGFSNRARKARLAEPQLREE A8K146_HUMAN A8K146_HUMAN GYCRGEAVYSRDCVHTLHSRDTWLKKARVVRLGEVPYKMVKGFSNRARKARLAEPQLREE B4DIP3_HUMAN B4DIP3_HUMAN GYCRGEAVYSRDCVHTLHSRDTWLKKARVVRLGEVPYKMVKGFSNRARKARLAEPQLREE MATCH ******.****.******* *****:**.* *.* ***** *:***:**** . :: CONSENSUS GYCRGEAVYSRDCVHTLHSRDTWLK?AR?VRLGE?PYKMVKGFSNR?RKAR????Q????

B7ZUY2_DANRE B7ZUY2_DANRE KDLALFGTWQTEEYQPPIAVDGKVPRNEFGNVYMFKSCMLPIGCVHVHLPNLHRVARKLN Q1LVE4_DANRE Q1LVE4_DANRE KDLALFGTWQTEEYQPPIAVDGKVPRNEFGNVYMFKSCMLPIGCVHVHLPNLHRVARKLN Q4S7W5_TETNG Q4S7W5_TETNG NDLALFGEWQTEEYQPPIAVDGKVPRNDFGNVYLFKPSMLPVGCVHLRLSNLHRVAKKLS B1H3H0_XENTR B1H3H0_XENTR NDLGLYGLWQTEEYQPPLAVDGKVPRNEYGNVYLFQPCMLPIGCAHLRVPNLHRVARKLD Q7TSZ1_MOUSE Q7TSZ1_MOUSE NDLGLYGHWQTEEYQPPIAVDGKVPRNEFGNVYLFLPSMMPVGCVQMTLPNLNRVARKLG XPC_MOUSE XPC_MOUSE NDLGLYGHWQTEEYQPPIAVDGKVPRNEFGNVYLFLPSMMPVGCVQMTLPNLNRVARKLG Q5RBA2_PONAB Q5RBA2_PONAB NDLGLFGYWQTEEYQPPVAVDGKVPRNEFGNVYLFLPSMMPIGCVQLNLPNLHRVARKLD XPC_HUMAN XPC_HUMAN NDLGLFGYWQTEEYQPPVAVDGKVPRNEFGNVYLFLPSMMPIGCVQLNLPNLHRVARKLD A8K146_HUMAN A8K146_HUMAN NDLGLFGYWQTEEYQPPVAVDGKVPRNEFGNVYLFLPSMMPIGCVQLNLPNLHRVARKLD B4DIP3_HUMAN B4DIP3_HUMAN NDLGLFGYWQTEEYQPPVAVDGKVPRNEFGNVYLFLPSMMPIGCVQLNLPNLHRVARKLD MATCH :**.*:* *********:*********::****:* ..*:*:**.:: :.**:***:**. CONSENSUS NDL?L?G?WQTEEYQPP?AVDGKVPRNEFGNVYLF?P?M?P?GCV???LPNLHRVARKL?

B7ZUY2_DANRE B7ZUY2_DANRE IDCALAVTGFDYHCGFAHAVNDGYIVCEEHEEILKAAWENEQEIQQKKEQEKREKRAVTN Q1LVE4_DANRE Q1LVE4_DANRE IDCALAVTGFDYHCGFAHAVNDGYIVCEEHEEILKAAWENEQEIQQKKEQEKREKRAVTN Q4S7W5_TETNG Q4S7W5_TETNG IDAAPAVTGFDFHGGYSHAVTDGYIVCEEFEEILQAAWLEEQELLKQKEKEKREKRVTSN B1H3H0_XENTR B1H3H0_XENTR IDCVKAITGFDFHGGYSHPVNDGYVVCEEHKDILLAAWENEQADIEQKQKEKREKRALGN Q7TSZ1_MOUSE Q7TSZ1_MOUSE IDCVQAITGFDFHGGYCHPVTDGYIVCEEFRDVLLAAWENEQAIIEKKEKEKKEKRALGN XPC_MOUSE XPC_MOUSE IDCVQAITGFDFHGGYCHPVTDGYIVCEEFRDVLLAAWENEQAIIEKKEKEKKEKRALGN Q5RBA2_PONAB Q5RBA2_PONAB IDCVQAITGFDFHGGYSHPVTDGYIVCEEFKDVLLTAWENEQAIIEKKEKEKREKRALGN XPC_HUMAN XPC_HUMAN IDCVQAITGFDFHGGYSHPVTDGYIVCEEFKDVLLTAWENEQAVIERKEKEKKEKRALGN A8K146_HUMAN A8K146_HUMAN IDCVQAITGFDFHGGYSHPVTDGYIVCEEFKDVLLTAWENEQAVIERKEKEKKEKRALGN B4DIP3_HUMAN B4DIP3_HUMAN IDCVQAITGFDFHGGYSHPVTDGYIVCEEFKDVLLTAWENEQAVIERKEKEKKEKRALGN MATCH **.. *:****:* *:.*.*.***:****..::* :** :** ::*::**:***. * CONSENSUS IDC??A?TGFDFHGGY?H?V?DGYIVCEE????L??AWENEQ?????KEKEK?EKRA??N

B7ZUY2_DANRE B7ZUY2_DANRE WTLLVKGLLIKERLKRRYGQQGLASGTGLKQGKEGGAEGLSSDEEKEGGAQSA--QAPPS Q1LVE4_DANRE Q1LVE4_DANRE WTLLVKGLLIKERLKRRYGQQGLASGTGLKQGKEGGAEGLSSDEEKEGGAQSA--QAPPS Q4S7W5_TETNG Q4S7W5_TETNG WALLVKGLLIREKLKKRYSTKNQGLRT-LADGDEPG--GLSSDEEAQEGASPAAKTASET B1H3H0_XENTR B1H3H0_XENTR WKLLVKGLLIRERLKARYGNKDTEL-----PGLSTGTNDFSSDEE--EKPKTE--TPAQD Q7TSZ1_MOUSE Q7TSZ1_MOUSE WKLLVIGLLIRERLKLRYGAKSEAAA---PHA-AGG--GLSSDEE-EGTSSQA--EAARV XPC_MOUSE XPC_MOUSE WKLLVRGLLIRERLKLRYGAKSEAAA---PHA-AGG--GLSSDEE-EGTSSQA--EAARV Q5RBA2_PONAB Q5RBA2_PONAB WKLLAKGLLIRERLKRRYGPKSEAAA---PHTDAGG--GLSSDEE-EGTSSQA--EAARI XPC_HUMAN XPC_HUMAN WKLLAKGLLIRERLKRRYGPKSEAAA---PHTDAGG--GLSSDEE-EGTSSQA--EAARI A8K146_HUMAN A8K146_HUMAN WKLLAKGLLIRERLKRRYGPKSEAAA---PHTDAGG--GLSSDEE-EGTSSQA--EAARI B4DIP3_HUMAN B4DIP3_HUMAN WKLLAKGLLIRERLKRRYGPKSEAAA---PHTDAGG--GLSSDEE-EGTSSQA--EAARI MATCH * **. ****:*:** **. :. * .:***** .. .. CONSENSUS W?LL?KGLLIRERLK?RYG?K??A??????????GG??GLSSDEE?EG????A???A???

B7ZUY2_DANRE B7ZUY2_DANRE LTASWPQNRKEEAEEKIV-----RRVSKREKRGEEKHLFPFEKV Q1LVE4_DANRE Q1LVE4_DANRE LTASWPQNRKEEAEEKIV-----RRVSNREKRGEEKHLFPFEKV Q4S7W5_TETNG Q4S7W5_TETNG LAMSWPQNRQEEEEKDFVSGLQKKKMTKREKRGQDKHLFPFEK- B1H3H0_XENTR B1H3H0_XENTR MAVSWPQNRQAEHTQAEKT----QRKSKKQKKGEENHLFPFEKL Q7TSZ1_MOUSE Q7TSZ1_MOUSE LAASWPQNREDPEQKSEY-----TKMTRKRRAAEASHLFPFEKL XPC_MOUSE XPC_MOUSE LAASWPQNREDPEQKSEY-----TKMTRKRRAAEASHLFPFEKL Q5RBA2_PONAB Q5RBA2_PONAB LAASWPQNR----------------------------------- XPC_HUMAN XPC_HUMAN LAASWPQNREDEEKQKLKGG---PKKTKREKKAAASHLFPFEKL A8K146_HUMAN A8K146_HUMAN LAASWPQNREGEEKQKLKGG---PKKTKREKKAAASHLFPFEQL B4DIP3_HUMAN B4DIP3_HUMAN LAASWPQNREDEEKQKLKGG---PKKTKREKKAAASHLFPFEQL MATCH :: ****** CONSENSUS LAASWPQNR???????????????????????????HLFPFE??


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