Alignment of the gene Family HBG000836 of HOVERGEN

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Isoforms are ON
Q28CC3_XENTR Q28CC3_XENTR ------------------------------------------------------------ Q4H2J4_CIOIN Q4H2J4_CIOIN ---------------------------------MDILPCGNIFNELQIIHDTGYFSALPS Q68FA0_XENTR Q68FA0_XENTR ---------------------------------MDVLPMCSIFQELQIVHETGYFSALPS Q7ZXK7_XENLA Q7ZXK7_XENLA ---------------------------------MDVLPMCSIFQELQIVHDTGYFSALPS Q66KQ9_XENLA Q66KQ9_XENLA --------------------------------------GCSIFQELQIVHDTGYFSALPS Q5ZI79_CHICK Q5ZI79_CHICK ---------------------------------MDVLPMCSIFQELQIVHDTGYFSALPS B4X5Z3_PIG B4X5Z3_PIG ---------------------------------MDVLPMCSIFQELQIVHETGYFSALPS KLF6_HUMAN KLF6_HUMAN ---------------------------------MDVLPMCSIFQELQIVHETGYFSALPS KLF6_RAT KLF6_RAT ---------------------------------MDVLPMCSIFQELQIVHETGYFSALPS KLF6_MOUSE KLF6_MOUSE ---------------------------------MDVLPMCSIFQELQIVHETGYFSALPS Q3U9J1_MOUSE Q3U9J1_MOUSE ---------------------------------MDVLPMCSIFQELQIVHETGYFSALPS Q3UGJ1_MOUSE Q3UGJ1_MOUSE KLSHALPGTVSARTPDRSPPCFPDSEDCLFQPDMDVLPMCSIFQELQIVHETGYFSALPS Q8VDZ7_MOUSE Q8VDZ7_MOUSE KLSPALPGTVSARTPDRSPPCFPDSEDCLFQPDMDVLPMCSIFQELQIVHETGYFSALPS Q8BPQ2_MOUSE Q8BPQ2_MOUSE KLSPALPGTVSARTPDRSPPCFPDSEDCLFQPDMDVLPMCSIFQELQIVHETGYFSALPS Q4SNL5_TETNG Q4SNL5_TETNG ---------------------------------MDVIPMCSIFQELQIVHDTGYFSALPS Q4SKQ7_TETNG Q4SKQ7_TETNG ---------------------------------MDVLPMCSIFQELQIVHDTGYFSALPS B5XF21_SALSA B5XF21_SALSA ---------------------------------MDVLPMCSIFQELQIVHDTGYFSALPS Q7ZUK3_DANRE Q7ZUK3_DANRE ---------------------------------MDVLPMCSIFQELQIVHDTGYFSALPS Q4SMA9_TETNG Q4SMA9_TETNG ---------------------------------MDVLANHSIFQELQLVHDTGYFSALPS Q502L8_DANRE Q502L8_DANRE ---------------------------------MDVLANYSIFQELQLVHDTGYFSAMPS Q5TYN4_DANRE Q5TYN4_DANRE ---------------------------------MDVLANYSIFQELQLVHDTGYFSAMPS B3KNE6_HUMAN B3KNE6_HUMAN ---------------------------------MDVLASYSIFQELQLVHDTGYFSALPS KLF7_HUMAN KLF7_HUMAN ---------------------------------MDVLASYSIFQELQLVHDTGYFSALPS B7Z4F7_HUMAN B7Z4F7_HUMAN ---------------------------------M-----------------------FPS Q4ZG79_HUMAN Q4ZG79_HUMAN ------------------------------------------------------------ Q7Z3H8_HUMAN Q7Z3H8_HUMAN ------------------------------------------------------------ Q96E51_HUMAN Q96E51_HUMAN ---------------------------------MDVLASYSIFQELQLVHDTGYFSALPS A1XSY7_PIG A1XSY7_PIG ---------------------------------MDVLASYSIFQELQLVHDTGYFSALPS A2AAB8_MOUSE A2AAB8_MOUSE ---------------------------------MDVLASYSIFQELQLVHDTGYFSALPS Q3UES6_MOUSE Q3UES6_MOUSE ---------------------------------MDVLASYSIFQELQLVHDTGYFSALPS KLF7_MOUSE KLF7_MOUSE ---------------------------------MDVLASYSIFQELQLVHDTGYFSALPS A2AAB7_MOUSE A2AAB7_MOUSE ---------------------------------MDVLASYSIFQELQLVHDTGYFSALPS Q0IHT4_XENTR Q0IHT4_XENTR ---------------------------------MDVLASYSIFQELQIVHDTGYFSAMPS Q7SY91_XENLA Q7SY91_XENLA ---------------------------------MDVLASYSIFQELQIVHDTGYFSAMPS MATCH CONSENSUS ?????????????????????????????????MDVL???SIFQELQ?VH?TGYFSA?PS

Q28CC3_XENTR Q28CC3_XENTR ------------------------------------------------------------ Q4H2J4_CIOIN Q4H2J4_CIOIN LEENW------------------------------------------------------- Q68FA0_XENTR Q68FA0_XENTR LEEYW------------------------------------------------------- Q7ZXK7_XENLA Q7ZXK7_XENLA LEEYW------------------------------------------------------- Q66KQ9_XENLA Q66KQ9_XENLA LEEYW------------------------------------------------------- Q5ZI79_CHICK Q5ZI79_CHICK LEEYW------------------------------------------------------- B4X5Z3_PIG B4X5Z3_PIG LEEYW------------------------------------------------------- KLF6_HUMAN KLF6_HUMAN LEEYW------------------------------------------------------- KLF6_RAT KLF6_RAT LEEYW------------------------------------------------------- KLF6_MOUSE KLF6_MOUSE LEEYW------------------------------------------------------- Q3U9J1_MOUSE Q3U9J1_MOUSE LEEYW------------------------------------------------------- Q3UGJ1_MOUSE Q3UGJ1_MOUSE LEEYW------------------------------------------------------- Q8VDZ7_MOUSE Q8VDZ7_MOUSE LEEYW------------------------------------------------------- Q8BPQ2_MOUSE Q8BPQ2_MOUSE LEEYW------------------------------------------------------- Q4SNL5_TETNG Q4SNL5_TETNG LEEYW------------------------------------------------------- Q4SKQ7_TETNG Q4SKQ7_TETNG LEEYW------------------------------------------------------- B5XF21_SALSA B5XF21_SALSA LEDYW------------------------------------------------------- Q7ZUK3_DANRE Q7ZUK3_DANRE LEEYW------------------------------------------------------- Q4SMA9_TETNG Q4SMA9_TETNG LEENWQQSGRLIPPRGTLSHPETRDPAMWTDSLERLSRRKKEENSDEGGRQTRAICPKTI Q502L8_DANRE Q502L8_DANRE LEENW------------------------------------------------------- Q5TYN4_DANRE Q5TYN4_DANRE LEENW------------------------------------------------------- B3KNE6_HUMAN B3KNE6_HUMAN LEETW------------------------------------------------------- KLF7_HUMAN KLF7_HUMAN LEETW------------------------------------------------------- B7Z4F7_HUMAN B7Z4F7_HUMAN ----W------------------------------------------------------- Q4ZG79_HUMAN Q4ZG79_HUMAN ------------------------------------------------------------ Q7Z3H8_HUMAN Q7Z3H8_HUMAN ------------------------------------------------------------ Q96E51_HUMAN Q96E51_HUMAN LEETW------------------------------------------------------- A1XSY7_PIG A1XSY7_PIG LEETW------------------------------------------------------- A2AAB8_MOUSE A2AAB8_MOUSE LEETW------------------------------------------------------- Q3UES6_MOUSE Q3UES6_MOUSE LEETW------------------------------------------------------- KLF7_MOUSE KLF7_MOUSE LEETW------------------------------------------------------- A2AAB7_MOUSE A2AAB7_MOUSE LEETW------------------------------------------------------- Q0IHT4_XENTR Q0IHT4_XENTR LEENW------------------------------------------------------- Q7SY91_XENLA Q7SY91_XENLA LEENW------------------------------------------------------- MATCH CONSENSUS LEE?W???????????????????????????????????????????????????????

Q28CC3_XENTR Q28CC3_XENTR -----GQAGV-----------------------------ISAFIKPPSQPISNTVKPILP Q4H2J4_CIOIN Q4H2J4_CIOIN -----QQTRFQMERYLQSEPLNYQTP---LHSGKDGINPWSKFLVPPGVKGGPGLSVEDI Q68FA0_XENTR Q68FA0_XENTR -----QQTCLELERYLQSEPCYVSAAEFKFDREEEL---WTKFILACEK---KEEPEQNI Q7ZXK7_XENLA Q7ZXK7_XENLA -----QQTCLELERYLQSEPCYVSAAEFKFDREEEL---WTKFIFACEK---KEEPDQNI Q66KQ9_XENLA Q66KQ9_XENLA -----QQTCLELERYLQSEPCYVSATEFKFDREEEL---WTKFILACEK---KEEPDQNI Q5ZI79_CHICK Q5ZI79_CHICK -----QQTCLELERYLQSEPCYVSASEIKFDNQEDL---WTKIILAREK---KEESELKT B4X5Z3_PIG B4X5Z3_PIG -----QQTCLELERYLQSEPCYVSASEIKFDSQEDL---WTKIILAREQ---KEDADLKM KLF6_HUMAN KLF6_HUMAN -----QQTCLELERYLQSEPCYVSASEIKFDSQEDL---WTKIILAREK---KEESELKI KLF6_RAT KLF6_RAT -----QQTCLELERYLQSEPCYVSASEIKFDNQEDL---WTKIILARER---KEESELKI KLF6_MOUSE KLF6_MOUSE -----QQTCLELERYLQSEPCYVSASEIKFDSQEDL---WTKFILAREK---KEESELKI Q3U9J1_MOUSE Q3U9J1_MOUSE -----QQTCLELERYLQSEPCYVSASEIKFDSQEDL---WTKFILARGEK--KEESELKI Q3UGJ1_MOUSE Q3UGJ1_MOUSE -----QQTCLELERYLQSEPCYVSASEIKFDSQEDL---WTKFILARGEK--KEESELKI Q8VDZ7_MOUSE Q8VDZ7_MOUSE -----QQTCLELERYLQSEPCYVSASEIKFDSQEDP---WTKFILARGEK--KEESELKI Q8BPQ2_MOUSE Q8BPQ2_MOUSE -----QQTCLELERYLQSEPCYVSASEIKFDSQEDL---WTKFILARGEK--KEESELKI Q4SNL5_TETNG Q4SNL5_TETNG -----QQTCLELERYLQSEP-YVSASDLKFESQEDL---WSKLMLACGDKS-KEPDPKIS Q4SKQ7_TETNG Q4SKQ7_TETNG -----QQTCLELERYLQSEP-YVSSSDLKFDGQEDL---WSKLILACGDKAKAECDPKLA B5XF21_SALSA B5XF21_SALSA -----QQTCLELERYLQSEPYVSTTSDIKLEPQEQDL--WSKLILACGDKAIDSDPKIPL Q7ZUK3_DANRE Q7ZUK3_DANRE -----QQTCLELERYLQSEP-YVSASDLKFEGQEDL---WSKLILACGDKG-DGNGSLPS Q4SMA9_TETNG Q4SMA9_TETNG KEVTRQQTCLELERYLQTEPKRLSEL---FDQDLDGL--LTPAYLK--EDGEEELSDTLL Q502L8_DANRE Q502L8_DANRE -----QQTCLELERYLQTEPKRLSDL---FDEELDGL--LSPSFM-KEDGDEDLLDPLLP Q5TYN4_DANRE Q5TYN4_DANRE -----QQTCLELERYLQTEPKRLSEL---FDEELDCL--LTPAFM-KGDSDEDLMDPLLP B3KNE6_HUMAN B3KNE6_HUMAN -----QQTCLELERYLQTEPRRISET---FGEDLDCF--LHASPPPCIEESFRRLDPLLL KLF7_HUMAN KLF7_HUMAN -----QQTCLELERYLQTEPRRISET---FGEDLDCF--LHASPPPCIEESFRRLDPLLL B7Z4F7_HUMAN B7Z4F7_HUMAN ------PTCLELERYLQTEPRRISET---FGEDLDCF--LHASPPPCIEESFRRLDPLLL Q4ZG79_HUMAN Q4ZG79_HUMAN -------TCLELERYLQTEPRRISET---FGEDLDCF--LHASPPPCIEESFRRLDPLLL Q7Z3H8_HUMAN Q7Z3H8_HUMAN ------MTCLELERYLQTEPRRISET---FGEDLDCF--LHASPPPCIEESFRRLDPLLL Q96E51_HUMAN Q96E51_HUMAN -----QQTCLELERYLQTEPRRISET---FGEDLDCF--LHASPPPCIEESFRRLDPLLL A1XSY7_PIG A1XSY7_PIG -----QQTCLELERYLQTEPRRISET---FGEDLDCF--LHASPPPCIEESFRRLDPLLL A2AAB8_MOUSE A2AAB8_MOUSE -----QQTCLELERYLQTEPRRISET---FGEDLDCF--LHASPPPCIEESFRRLDPLLL Q3UES6_MOUSE Q3UES6_MOUSE -----QQTCLELERYLQTEPRRISET---FGEDLDCF--LHASPPPCIEESFRRLDPLLL KLF7_MOUSE KLF7_MOUSE -----QQTCLELERYLQTEPRRISET---FGEDLDCF--LHASPPPCIEESFRRLDPLLL A2AAB7_MOUSE A2AAB7_MOUSE -----QQTCLELERYLQTEPRRISET---FGEDLDCF--LHASPPPCIEESFRRLDPLLL Q0IHT4_XENTR Q0IHT4_XENTR -----QQTCLELERYLQTEPKKMSET---FGEDLDCF--LNTSIAQAVDGTARKIDSIVI Q7SY91_XENLA Q7SY91_XENLA -----QQTCLELERYLQTEPKKMSET---FGEDLDCF--LNTSIAQAADGTACKIDSIVI MATCH : . CONSENSUS ?????QQTCLELERYLQ?EP???S?????F????D?????????????????????????

Q28CC3_XENTR Q28CC3_XENTR ---------------------------------------QSSP----VSQPVLMGAPVSQ Q4H2J4_CIOIN Q4H2J4_CIOIN ----QTARKCCGLVRNSSSGVGSMSSWDMSSGEVSP-----VPGVG-LSDPLKDALKVLK Q68FA0_XENTR Q68FA0_XENTR GCVSPEDISDCQN----SETNSLNSDVSSESSDSSE---ELSPTSKFTSDPISDVLATN- Q7ZXK7_XENLA Q7ZXK7_XENLA SCVSPEDISDCQN----SETNSLNSDVSSESSDSSE---ELSPTSKFTSDTISDVLATN- Q66KQ9_XENLA Q66KQ9_XENLA SCVSPEDISDCQN----SETNSLNSDVSSESSDSSE---ELSPTSKFTSDTISDVLATN- Q5ZI79_CHICK Q5ZI79_CHICK ACVPKEDSSTSQN----LETNSLNSDVSSESSDSSE---ELSPTTKFTSDPISDVL-TNS B4X5Z3_PIG B4X5Z3_PIG SSSPPEDALNSPGFGYNLETNSLNSDVSSESSDSSE---ELSPTTKFTSDPIGEVL-VTS KLF6_HUMAN KLF6_HUMAN SSSPPEDTLISPSFCYNLETNSLNSDVSSESSDSSE---ELSPTAKFTSDPIGEVL-VSS KLF6_RAT KLF6_RAT SSSPPEDSLISSGFNYNLETNSLNSDVSSESSDSSE---ELSPTTKFTSDPIGEVL-VNS KLF6_MOUSE KLF6_MOUSE SSSPPEDSLISSSFNYNLETNSLNSDVSSESSDSSE---ELSPTTKFTSDPIGEVL-VNS Q3U9J1_MOUSE Q3U9J1_MOUSE SSSPPEDSLISSSFNYNLETNSLNSDVSSESSDSSE---ELSPTTKFTSDPIGEVL-VNS Q3UGJ1_MOUSE Q3UGJ1_MOUSE SSSPPEDSLISSSFNYNLETNSLNSDVSSESSDSSE---ELSPTTKFTSDPIGEVL-VNS Q8VDZ7_MOUSE Q8VDZ7_MOUSE SSSPPEDSLISSSFNYNLETNSLNSDVSSESSDSSE---ELSPTTKFTSDPIGEVL-VNS Q8BPQ2_MOUSE Q8BPQ2_MOUSE SSSPPEDSLISSSFNYNLETNSLNSDVSSESSDSSE---ELSPTTKFTSDPIGEVL-VNS Q4SNL5_TETNG Q4SNL5_TETNG HIKDEEDNQDSQH----LDATGFNSDASSEASDSSE---ELSPTLDFSSSSLTDLLGDGS Q4SKQ7_TETNG Q4SKQ7_TETNG -AAPEEDNQDSQI----LDSNSVNSDASSEASDSSE---ELSPTHSFTSNPLGVL--VGS B5XF21_SALSA B5XF21_SALSA --VKEEDNQDGQI----LETNSVNSDASSEASDSSV---ELSPTHSFTLNPLGSVL-AGS Q7ZUK3_DANRE Q7ZUK3_DANRE --VKEDDNQDCQI----LETNSMNSDASSEASDSSE---ELSPTHIFTSNPLGSVLTESA Q4SMA9_TETNG Q4SMA9_TETNG ----PSLPSIPEP---PSPPPVVLCPAQKNLSSSGVMKKDFKPKAQ-GLENVEAVEGVHQ Q502L8_DANRE Q502L8_DANRE SLNNP--------------------PSPPQRKETRS---SISP---------DATLGVNA Q5TYN4_DANRE Q5TYN4_DANRE --------SLSDE----PSPPPLLVSLPKTLHTPAN---TKST----DAGLKEASGGVNP B3KNE6_HUMAN B3KNE6_HUMAN ----PVEAAICEK----SSAVDILLSRDKLLSETCL---SLQP----ASSSLDSYTAVNQ KLF7_HUMAN KLF7_HUMAN ----PVEAAICEK----SSAVDILLSRDKLLSETCL---SLQP----ASSSLDSYTAVNQ B7Z4F7_HUMAN B7Z4F7_HUMAN ----PVEAAICEK----SSAVDILLSRDKLLSETCL---SLQP----ASSSLDSYTAVNQ Q4ZG79_HUMAN Q4ZG79_HUMAN ----PVEAAICEK----SSAVDILLSRDKLLSETCL---SLQP----ASSSLDSYTAVNQ Q7Z3H8_HUMAN Q7Z3H8_HUMAN ----PVEAAICEK----SSAVDILLSRDKLLSETCL---SLQP----ASSSLDSYTAVNQ Q96E51_HUMAN Q96E51_HUMAN ----PVEAAICEK----SSAVDILLSRDKLLSETCL---SLQP----ASSSLDSYTAVNQ A1XSY7_PIG A1XSY7_PIG ----PVEATICEK----SSAVDILLSRDKLLSETCL---SLQP----ASSSLDSYTAVNQ A2AAB8_MOUSE A2AAB8_MOUSE ----PVEATICEK----SSAVDILLSRDKLLSETCL---SLQP----TSSSLDSYTAVNQ Q3UES6_MOUSE Q3UES6_MOUSE ----PVEATICEK----SSAVDILLSRDKLLSETCL---SLQP----TSSSLDSYTAVNQ KLF7_MOUSE KLF7_MOUSE ----PVEATICEK----SSAVDILLSRDKLLSETCL---SLQP----TSSSLDSYTAVNQ A2AAB7_MOUSE A2AAB7_MOUSE ----PVEATICEK----SSAVDILLSRDKLLSETCL---SLQP----TSSSLDSYTAVNQ Q0IHT4_XENTR Q0IHT4_XENTR ----PVDISAYEK----RPSMDVLLSQDKLLSETCV---SLQP----ASSATECYTSVNQ Q7SY91_XENLA Q7SY91_XENLA ----PVDISTYEK----RPSMDVLLSQDKLLSETCV---SLQP-------ATECYTSVNQ MATCH . CONSENSUS ???????????????????????????????S????????L?P?????S???????????

Q28CC3_XENTR Q28CC3_XENTR GALMLVL----PQAP-IPQSPQQCPQTLVA-VGNTKLLPLAPAPVFIA------------ Q4H2J4_CIOIN Q4H2J4_CIOIN AS-TLALGLTPPSSPEFELSLCGFGDKFIE-KKMDSNQTLRLSEVDLSAFTAQVAQRVAS Q68FA0_XENTR Q68FA0_XENTR GTLSSSVTSTPPSSPEQGKDP--SCHLWNA-ITGELHSPGKVRCGSIG------------ Q7ZXK7_XENLA Q7ZXK7_XENLA GTLSSSVTSTPPSSPEQSKDP--SCHLWNA-VTGELHSPGKVRCGSFG------------ Q66KQ9_XENLA Q66KQ9_XENLA GTLSSSVTSTPPSSPEQGKDP--SCHLWNA-ITGELHSPGKVRCGSIG------------ Q5ZI79_CHICK Q5ZI79_CHICK GNLCSSVTSTPPSSPELSKEP--SSQLWNC-TPGELHSPGKIRTGTAG------------ B4X5Z3_PIG B4X5Z3_PIG GNLSSSVTSTPPSSPELSRE---PSHLWGC-VPGELHPPGKARSGTAG------------ KLF6_HUMAN KLF6_HUMAN GKLSSSVTSTPPSSPELSRE---PSQLWGC-VPGELPSPGKVRSGTSG------------ KLF6_RAT KLF6_RAT GNLSSSVISTPPSSPEVNRE---SSQLWGC-GPGDLPSPGKVRSGTSG------------ KLF6_MOUSE KLF6_MOUSE GNLSSSVISTPPSSPEVNRE---SSQLWGC-GPGDLPSPGKVRSGTSG------------ Q3U9J1_MOUSE Q3U9J1_MOUSE GNLSSSVISTPPSSPEVNRE---SSQLWGC-GPGDLPSPGKVRSGTSG------------ Q3UGJ1_MOUSE Q3UGJ1_MOUSE GNLSSSVISTPPSSPEVNRE---SSQLWGC-GPGDLPSPGKVRSGTSG------------ Q8VDZ7_MOUSE Q8VDZ7_MOUSE GNLSSSVISTPPSSPEVNRE---SSQLWGC-GPGDLPSPGKVRSGTSG------------ Q8BPQ2_MOUSE Q8BPQ2_MOUSE GNLSSSVISTPPSSPEVNRE---SSQLWGC-GPGDLPSPGKVRSGTSG------------ Q4SNL5_TETNG Q4SNL5_TETNG EDLGSAIISTPPSSPELGKE-VSVTQGWSG-VQTVLHSPGKIRTGGLE------------ Q4SKQ7_TETNG Q4SKQ7_TETNG GPFSPSVISTPPSSPEANSEAVGVTTAWGA-AHTELHSPEAACAG--------------- B5XF21_SALSA B5XF21_SALSA GPFSPSIISTPPSSPEVSSEP-SISQGWGS-VNTELTLPVKVRTGGIG------------ Q7ZUK3_DANRE Q7ZUK3_DANRE HHLSSSIISTPPSSPEMPQEP-GVPQVWGS-TQTDLHIPVKIRQNGLG------------ Q4SMA9_TETNG Q4SMA9_TETNG AQLSAVTSLTPPSSPELGRHLVKPNQTLTASADGTLTLKLVARKVGLS------AARLVA Q502L8_DANRE Q502L8_DANRE AQLNAVTSLTPPSSPELGRHLVKPTHTLSASPDGTLTLKLVARKVGLSSAKL--VAAHPV Q5TYN4_DANRE Q5TYN4_DANRE AQLNAVTSLTPPSSPELGRHLVKPTQTLTATADGTLTLKLVAKKVGLGAAKLVATHSIPS B3KNE6_HUMAN B3KNE6_HUMAN AQLNAVTSLTPPSSPELSRHLVKTSQTLSA-MDGTVTLKLVAKKAALSSVKVGGVATAAA KLF7_HUMAN KLF7_HUMAN AQLNAVTSLTPPSSPELSRHLVKTSQTLSA-VDGTVTLKLVAKKAALSSVKVGGVATAAA B7Z4F7_HUMAN B7Z4F7_HUMAN AQLNAVTSLTPPSSPELSRHLVKTSQTLSA-VDGTVTLKLVAKKAALSSVKVGGVATAAA Q4ZG79_HUMAN Q4ZG79_HUMAN AQLNAVTSLTPPSSPELSRHLVKTSQTLSA-VDGTVTLKLVAKKAALSSVKVGGVATAAA Q7Z3H8_HUMAN Q7Z3H8_HUMAN AQLNAVTSLTPPSSPELSRHLVKTSQTLSA-VDGTVTLKLVAKKAALSSVKVGGVATAAA Q96E51_HUMAN Q96E51_HUMAN AQLNAVTSLTPPSSPELSRHLVKTSQTLSA-VDGTVTLKLVAKKAALSSVKV-------- A1XSY7_PIG A1XSY7_PIG AQLNAVTSLTPPSSPELSRHLVKTSQTLSA-VDGTVTLKLVAKKAALSSVKVGGVATAAA A2AAB8_MOUSE A2AAB8_MOUSE AQLNAVTSLTPPSSPELSRHLVKTSQTLSA-VDGTVTLKLVAKKASLSSVKVGGVA-AAA Q3UES6_MOUSE Q3UES6_MOUSE AQLNAVTSLTPPSSPELSRHLVKTSQTLSA-VDGTVTLKLVAKKASLSSVKVGGVA-AAA KLF7_MOUSE KLF7_MOUSE AQLNAVTSLTPPSSPELSRHLVKTSQTLSA-VDGTVTLKLVAKKASLSSVKVGGVA-AAA A2AAB7_MOUSE A2AAB7_MOUSE AQLNAVTSLTPPSSPEL------------------------------------------- Q0IHT4_XENTR Q0IHT4_XENTR AQLNAVTSLTPPSSPELSRHLVKTPQSLSA-VDGTVTLKLVAKKASVS------LGKAAE Q7SY91_XENLA Q7SY91_XENLA AQLNAVTSLTPPSSPELSRHLVKTPQSLSV-VDGTVTLKLVAKKATVS------LGKAAE MATCH *.:* CONSENSUS ??L??????TPPSSPE????????????????????????????????????????????

Q28CC3_XENTR Q28CC3_XENTR ------------------------SG------QSS-----PPQMDFSRRRNYVCNFSGCR Q4H2J4_CIOIN Q4H2J4_CIOIN GGATQRRNRIGIKSIDSSIRVKSQSG------EDS-----DN----CKKRIHRCDYPNCR Q68FA0_XENTR Q68FA0_XENTR --------KTLDHG-------SPTGG------ETS-----PD----GRKRVHKCLFNGCK Q7ZXK7_XENLA Q7ZXK7_XENLA --------KTLEHG-------SPTGG------ESS-----PD----GRKRIHKCLFNGCK Q66KQ9_XENLA Q66KQ9_XENLA --------KTLEHG-------SPTGG------ETS-----PD----GRKRIHKCLFNGCK Q5ZI79_CHICK Q5ZI79_CHICK --------KTAEKG-------TPANG------DTS-----PD----GRRRVHRCHFNGCR B4X5Z3_PIG B4X5Z3_PIG --------KPGDKG----------SG------DAS-----PD----GRRRVHRCHFNGCR KLF6_HUMAN KLF6_HUMAN --------KPGDKG----------NG------DAS-----PD----GRRRVHRCHFNGCR KLF6_RAT KLF6_RAT --------KSGDKG----------SG------DAS-----PD----GRRRVHRCHFNGCR KLF6_MOUSE KLF6_MOUSE --------KSGDKG----------NG------DAS-----PD----GRRRVHRCHFNGCR Q3U9J1_MOUSE Q3U9J1_MOUSE --------KSGDKG----------NG------DAS-----PD----GRRRVHRCHFNGCR Q3UGJ1_MOUSE Q3UGJ1_MOUSE --------KSGDKG----------NG------DAS-----PD----GRRRVHRCHFNGCR Q8VDZ7_MOUSE Q8VDZ7_MOUSE --------KSGDKG----------NG------DAS-----PD----GRRRVHRCHFNGCR Q8BPQ2_MOUSE Q8BPQ2_MOUSE --------KSGDKG----------NG------DAS-----PD----GRRRVHRCHFNGCR Q4SNL5_TETNG Q4SNL5_TETNG --------RSGLTS-----------G------EAS-----PD----GRKRVHRCQFNGCR Q4SKQ7_TETNG Q4SKQ7_TETNG --------KSAEKT-------GLVCG------DAS-----PD----SRRRVHRCQFNGCR B5XF21_SALSA B5XF21_SALSA --------KNSAKS-------GLVGG------DAS-----PD----GRRRVHRCHFNGCR Q7ZUK3_DANRE Q7ZUK3_DANRE --------KALDKT--------TSGG------DAS-----PD----GRRRVHRCHFNGCR Q4SMA9_TETNG Q4SMA9_TETNG AHALPVRVKEEDEG------------------AACMIGELPE----NKKRIHRCQFNGCR Q502L8_DANRE Q502L8_DANRE PLSPQHGSTGTQSD-------GEQGGTCTIGVGDM-----AE----NKKRVHRCQFNGCR Q5TYN4_DANRE Q5TYN4_DANRE PP------NRGTQS-------DGEGGLGTVGGGDI-----PE----NKKRVHRCQFNGCR B3KNE6_HUMAN B3KNE6_HUMAN AVTAAGAVKSGQSD-------SDQGGLGA---EAC-----PE----NKKRVHRCQFNGCR KLF7_HUMAN KLF7_HUMAN AVTAAGAVKSGQSD-------SDQGGLGA---EAC-----PE----NKKRVHRCQFNGCR B7Z4F7_HUMAN B7Z4F7_HUMAN AVTAAGAVKSGQSD-------SDQGGLGA---EAC-----PE----NKKRVHRCQFNGCR Q4ZG79_HUMAN Q4ZG79_HUMAN AVTAAGAVKSGQSD-------SDQGGLGA---EAC-----PE----NKKRVHRCQFNGCR Q7Z3H8_HUMAN Q7Z3H8_HUMAN AVTAAGAVKSGQSD-------SDQGGLGA---EAC-----PE----NKKRVHRCQFNGCR Q96E51_HUMAN Q96E51_HUMAN ------------------------------------------------------------ A1XSY7_PIG A1XSY7_PIG AVAAAGTVKSGQSD-------SEQGGVGA---EAC-----PE----NKKRVHRCQFNGCR A2AAB8_MOUSE A2AAB8_MOUSE AVTPAGAVKSGQSD-------SEQGGGGA---DTC-----PE----NKKRVHRCQFNGCR Q3UES6_MOUSE Q3UES6_MOUSE AVTPAGAVKSGQSD-------SEQGGGGA---DTC-----PE----NKKRVHRCQFNGCR KLF7_MOUSE KLF7_MOUSE AVTPAGAVKSGQSD-------SEQGGGGA---DTC-----PE----NKKRVHRCQFNGCR A2AAB7_MOUSE A2AAB7_MOUSE ------------------------------------------------------------ Q0IHT4_XENTR Q0IHT4_XENTR SASTAVTSKCGLSD-------SEQTGGPG---EAS-----PE----NKKRVHRCQFNGCR Q7SY91_XENLA Q7SY91_XENLA SASTAVTSKCGQSD-------SEQTGGPG---EAS-----PE----NKKRVHRCQFNGCR MATCH CONSENSUS ?????????????????????????G??????????????P????????R?HRC?FNGCR

Q28CC3_XENTR Q28CC3_XENTR KTYFKSSHLKAHLRTH---------------------------TGEKPFSCNW----EGC Q4H2J4_CIOIN Q4H2J4_CIOIN KVYTKSSHLKAHQRTH---------------------------TGEKPYKCNW----EGC Q68FA0_XENTR Q68FA0_XENTR KVYTKSSHLKAHQRTH---------------------------TGEKPYRCSW----EGC Q7ZXK7_XENLA Q7ZXK7_XENLA KVYTKSSHLKAHQRTH---------------------------TGEKPYRCSW----EGC Q66KQ9_XENLA Q66KQ9_XENLA KVYTKSSHLKAHQRTH---------------------------TGEKPYRCSW----EGC Q5ZI79_CHICK Q5ZI79_CHICK KVYTKSSHLKAHQRTH---------------------------TGEKPYRCSW----EGC B4X5Z3_PIG B4X5Z3_PIG KVYTKSSHLKAHQRTH---------------------------TGEKPYRCSW----EGC KLF6_HUMAN KLF6_HUMAN KVYTKSSHLKAHQRTH---------------------------TGEKPYRCSW----EGC KLF6_RAT KLF6_RAT KVYTKSSHLKAHQRTH---------------------------TGEKPYRCSW----EGC KLF6_MOUSE KLF6_MOUSE KVYTKSSHLKAHQRTH---------------------------TGEKPYRCSW----EGC Q3U9J1_MOUSE Q3U9J1_MOUSE KVYTKSSHLKAHQRTH---------------------------TGEKPYRCSW----EGC Q3UGJ1_MOUSE Q3UGJ1_MOUSE KVYTKSSHLKAHQRTH---------------------------TGEKPYRCSW----EGC Q8VDZ7_MOUSE Q8VDZ7_MOUSE KVYTKSSHLKAHQRTH---------------------------TGEKPYRCSW----EGC Q8BPQ2_MOUSE Q8BPQ2_MOUSE KVYTKSSHLKAHQRTH---------------------------TGEKPYRCSW----EGC Q4SNL5_TETNG Q4SNL5_TETNG KVYTKSSHLKAHQRTH---------------------------TGEKPYRCSW----EGC Q4SKQ7_TETNG Q4SKQ7_TETNG KVYTKSSHLKAHQRTHTAGVADQTRFSHSGQTCSSATDVPTVPTGEKPYRCSW----EGC B5XF21_SALSA B5XF21_SALSA KVYTKSSHLKAHQRTH---------------------------TGEKPYRCSW----EGC Q7ZUK3_DANRE Q7ZUK3_DANRE KVYTKSSHLKAHQRTH---------------------------TGEKPYRCSW----EGC Q4SMA9_TETNG Q4SMA9_TETNG KVYTKSSHLKAHQRTH---------------------------TGEKPYKCSW----EGC Q502L8_DANRE Q502L8_DANRE KVYTKSSHLKAHQRTH---------------------------TGEKPYKCSW----EGC Q5TYN4_DANRE Q5TYN4_DANRE KVYTKSSHLKAHQRTH---------------------------TGEKPYKCSW----EGC B3KNE6_HUMAN B3KNE6_HUMAN KVYTKSSHLKAHQRTH---------------------------TGEKPYKCSW----EGC KLF7_HUMAN KLF7_HUMAN KVYTKSSHLKAHQRTH---------------------------TGEKPYKCSW----EGC B7Z4F7_HUMAN B7Z4F7_HUMAN KVYTKSSHLKAHQRTH---------------------------TGEKPYKCSW----EGC Q4ZG79_HUMAN Q4ZG79_HUMAN KVYTKSSHLKAHQRTH---------------------------TGEKPYKCSW----EGC Q7Z3H8_HUMAN Q7Z3H8_HUMAN KVYTKSSHLKAHQRTH---------------------------TGEKPYKCSW----EGC Q96E51_HUMAN Q96E51_HUMAN -----RSLISAHGRDV-----------------------------------------SGV A1XSY7_PIG A1XSY7_PIG KVYTKSSHLKAHQRTH---------------------------TGEKPYKCSW----EGC A2AAB8_MOUSE A2AAB8_MOUSE KVYTKSSHLKAHQRTH---------------------------TGVRSLTSAHGKDASGV Q3UES6_MOUSE Q3UES6_MOUSE KVYTKSSHLKAHQRTH---------------------------TGEKPYKCSW----EGC KLF7_MOUSE KLF7_MOUSE KVYTKSSHLKAHQRTH---------------------------TGEKPYKCSW----EGC A2AAB7_MOUSE A2AAB7_MOUSE ------------------------------------------------------------ Q0IHT4_XENTR Q0IHT4_XENTR KVYTKSSHLKAHQRTH---------------------------TGEKPYKCSW----EGC Q7SY91_XENLA Q7SY91_XENLA KVYTKSSHLKAHQRTH---------------------------TGEKPYKCSW----EGC MATCH CONSENSUS KVYTKSSHLKAHQRTH???????????????????????????TGEKPY?CSW????EGC

Q28CC3_XENTR Q28CC3_XENTR DKKFARSDELSRHRRTHTGEKKFACPVCDRRFMRSDHLTKHARRHMTTKKVPAWQAEVGK Q4H2J4_CIOIN Q4H2J4_CIOIN EWRFARSDELTRHYRKHTGAKPFKCGQCDRCFSRSDHLALHMKRHA-------------- Q68FA0_XENTR Q68FA0_XENTR EWRFARSDELTRHFRKHTGAKPFKCSHCDRCFSRSDHLALHMKRHI-------------- Q7ZXK7_XENLA Q7ZXK7_XENLA EWRFARSDELTRHFRKHTGAKPFKCSHCDRCFSRSDHLALHMKRHI-------------- Q66KQ9_XENLA Q66KQ9_XENLA EWRFARSDELTRHFRKHTGAKPFKCSHCDRCFSRSDHLALHMKRHI-------------- Q5ZI79_CHICK Q5ZI79_CHICK EWRFARSDELTRHFRKHTGAKPFKCSHCDRCFSRSDHLALHMKRHL-------------- B4X5Z3_PIG B4X5Z3_PIG EWRFARSDELTRHFRKHTGAKPFKCSHCDRCFSRSDHLALHMKRHL-------------- KLF6_HUMAN KLF6_HUMAN EWRFARSDELTRHFRKHTGAKPFKCSHCDRCFSRSDHLALHMKRHL-------------- KLF6_RAT KLF6_RAT EWRFARSDELTRHFRKHTGAKPFKCSHCDRCFSRSDHLALHMKRHL-------------- KLF6_MOUSE KLF6_MOUSE EWRFARSDELTRHFRKHTGAKPFKCSHCDRCFSRSDHLALHMKRHL-------------- Q3U9J1_MOUSE Q3U9J1_MOUSE EWRFARSDELTRHFRKHTGAKPFKCSHCDRCFSRSDHLALHMKRHL-------------- Q3UGJ1_MOUSE Q3UGJ1_MOUSE EWRFARSDELTRHFRKHTGAKPFKCSHCDRCFSRSDHLALHMKRHL-------------- Q8VDZ7_MOUSE Q8VDZ7_MOUSE EWRFARSDELTRHFRKHTGAKPFKCSHCDRCFSRSDHLALHMKRHL-------------- Q8BPQ2_MOUSE Q8BPQ2_MOUSE EWRFARSDELTRHFRKHTGAKPFKCSHCDRCFSRSDHLALHMKRHL-------------- Q4SNL5_TETNG Q4SNL5_TETNG EWRFARSDELTRHFRKHTGAKPFKCSHCDRCFSRSDHLALHMKRHI-------------- Q4SKQ7_TETNG Q4SKQ7_TETNG EWRFARSDELTRHFRKHTGAKPFKCSHCDRCFSRSDHLALHMKRHI-------------- B5XF21_SALSA B5XF21_SALSA EWRFARSDELTRHFRKHTGAKPFKCSHCDRCFSRSDHLALHMKRHL-------------- Q7ZUK3_DANRE Q7ZUK3_DANRE EWRFARSDELTRHFRKHTGAKPFKCSHCDRCFSRSDHLALHMKRHL-------------- Q4SMA9_TETNG Q4SMA9_TETNG EWRFARSDELTRHYRKHTGAKPFKCNHCDRCFSRSDHLALHMKRHI-------------- Q502L8_DANRE Q502L8_DANRE EWRFARSDELTRHYRKHTGAKPFKCNHCDRCFSRSDHLALHMKRHV-------------- Q5TYN4_DANRE Q5TYN4_DANRE EWRFARSDELTRHYRKHTGAKPFKCNHCDRCFSRSDHLALHMKRHI-------------- B3KNE6_HUMAN B3KNE6_HUMAN EWRFARSDELTRHYRKHTGAKPFKCNHCDRCFSRSDHLALHMKRHI-------------- KLF7_HUMAN KLF7_HUMAN EWRFARSDELTRHYRKHTGAKPFKCNHCDRCFSRSDHLALHMKRHI-------------- B7Z4F7_HUMAN B7Z4F7_HUMAN EWRFARSDELTRHYRKHTGAKPFKCNHCDRCFSRSDHLALHMKRHI-------------- Q4ZG79_HUMAN Q4ZG79_HUMAN EWRFARSDELTRHYRKHTGAKPFKCNHCDRCFSRSDHLALHMKRHI-------------- Q7Z3H8_HUMAN Q7Z3H8_HUMAN EWRFARSDELTRHYRKHTGAKPFKCNHCDRCFSRSDHLALHMKRHI-------------- Q96E51_HUMAN Q96E51_HUMAN LHEAMSSRGTTGNTQVQS---PSNATTATGVFP-----GLTILPST-------------- A1XSY7_PIG A1XSY7_PIG EWRFARSDELTRHYRKHTGAKPFKCNHCDRCFSRSDHLALHMKRHI-------------- A2AAB8_MOUSE A2AAB8_MOUSE LHGAMSSQGTTGNTQVQS---PLSVTTATGVSP-----GLTILRSI-------------- Q3UES6_MOUSE Q3UES6_MOUSE EWRFARSDELTRHYRKHTGAKPFKCNHCDR------------------------------ KLF7_MOUSE KLF7_MOUSE EWRFARSDELTRHYRKHTGAKPFKCNHCDRCFSRSDHLALHMKRHI-------------- A2AAB7_MOUSE A2AAB7_MOUSE ------------------------------------------------------------ Q0IHT4_XENTR Q0IHT4_XENTR EWRFARSDELTRHYRKHTGAKPFKCNHCDRCFSRSDHLALHMKRHI-------------- Q7SY91_XENLA Q7SY91_XENLA EWRSARSDELTRHYRKHTGAKPFKCNHCDRCFSRSDHLALHMKRHI-------------- MATCH CONSENSUS EWRFARSDELTRH?RKHTGAKPFKC?HCDRCFSRSDHLALHMKRH???????????????

Q28CC3_XENTR Q28CC3_XENTR LNRISGTDKVQSSGPSLGMVVSMPAPI Q4H2J4_CIOIN Q4H2J4_CIOIN --------------------------- Q68FA0_XENTR Q68FA0_XENTR --------------------------- Q7ZXK7_XENLA Q7ZXK7_XENLA --------------------------- Q66KQ9_XENLA Q66KQ9_XENLA --------------------------- Q5ZI79_CHICK Q5ZI79_CHICK --------------------------- B4X5Z3_PIG B4X5Z3_PIG --------------------------- KLF6_HUMAN KLF6_HUMAN --------------------------- KLF6_RAT KLF6_RAT --------------------------- KLF6_MOUSE KLF6_MOUSE --------------------------- Q3U9J1_MOUSE Q3U9J1_MOUSE --------------------------- Q3UGJ1_MOUSE Q3UGJ1_MOUSE --------------------------- Q8VDZ7_MOUSE Q8VDZ7_MOUSE --------------------------- Q8BPQ2_MOUSE Q8BPQ2_MOUSE --------------------------- Q4SNL5_TETNG Q4SNL5_TETNG --------------------------- Q4SKQ7_TETNG Q4SKQ7_TETNG --------------------------- B5XF21_SALSA B5XF21_SALSA --------------------------- Q7ZUK3_DANRE Q7ZUK3_DANRE --------------------------- Q4SMA9_TETNG Q4SMA9_TETNG --------------------------- Q502L8_DANRE Q502L8_DANRE --------------------------- Q5TYN4_DANRE Q5TYN4_DANRE --------------------------- B3KNE6_HUMAN B3KNE6_HUMAN --------------------------- KLF7_HUMAN KLF7_HUMAN --------------------------- B7Z4F7_HUMAN B7Z4F7_HUMAN --------------------------- Q4ZG79_HUMAN Q4ZG79_HUMAN --------------------------- Q7Z3H8_HUMAN Q7Z3H8_HUMAN --------------------------- Q96E51_HUMAN Q96E51_HUMAN --------------------------- A1XSY7_PIG A1XSY7_PIG --------------------------- A2AAB8_MOUSE A2AAB8_MOUSE --------------------------- Q3UES6_MOUSE Q3UES6_MOUSE --------------------------- KLF7_MOUSE KLF7_MOUSE --------------------------- A2AAB7_MOUSE A2AAB7_MOUSE --------------------------- Q0IHT4_XENTR Q0IHT4_XENTR --------------------------- Q7SY91_XENLA Q7SY91_XENLA --------------------------- MATCH CONSENSUS ???????????????????????????


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