Alignment of the gene Family HBG000976 of HOVERGEN

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Threshold: 50% 80% 100%
Size: Bigger Smaller Normal
Isoforms are ON
Q4SNL3_TETNG Q4SNL3_TETNG ------------------------------------------------------------ Q4SKQ6_TETNG Q4SKQ6_TETNG ------------------------------------------------------------ Q5ZHU4_CHICK Q5ZHU4_CHICK ------------------------------------------------------------ Q6PF67_XENLA Q6PF67_XENLA ------------------------------------------------------------ A2RV78_XENLA A2RV78_XENLA ------------------------------------------------------------ Q6P4Y8_XENTR Q6P4Y8_XENTR ------------------------------------------------------------ K6PP_RAT K6PP_RAT ------------------------------------------------------------ K6PP_MOUSE K6PP_MOUSE ------------------------------------------------------------ Q8C605_MOUSE Q8C605_MOUSE ------------------------------------------------------------ K6PP_RABIT K6PP_RABIT ------------------------------------------------------------ K6PP_PONAB K6PP_PONAB ------------------------------------------------------------ O14943_HUMAN O14943_HUMAN ------------------------------------------------------------ B3KS15_HUMAN B3KS15_HUMAN ------------------------------------------------------------ Q5VSR7_HUMAN Q5VSR7_HUMAN ------------------------------------------------------------ K6PP_HUMAN K6PP_HUMAN ------------------------------------------------------------ Q5VSR8_HUMAN Q5VSR8_HUMAN ------------------------------------------------------------ Q8WTZ9_HUMAN Q8WTZ9_HUMAN ------------------------------------------------------------ K6PF_RABIT K6PF_RABIT ------------------------------------------------------------ K6PF_HORSE K6PF_HORSE ------------------------------------------------------------ K6PF_PIG K6PF_PIG ------------------------------------------------------------ Q1HL06_PIG Q1HL06_PIG ------------------------------------------------------------ K6PF_BOVIN K6PF_BOVIN ------------------------------------------------------------ K6PF_CANFA K6PF_CANFA ------------------------------------------------------------ Q1LZL7_MOUSE Q1LZL7_MOUSE ------------------------------------------------------------ K6PF_RAT K6PF_RAT ------------------------------------------------------------ Q52KS1_RAT Q52KS1_RAT ------------------------------------------------------------ Q99K08_MOUSE Q99K08_MOUSE ------------------------------------------------------------ K6PF_MOUSE K6PF_MOUSE ------------------------------------------------------------ K6PF_MACFA K6PF_MACFA ------------------------------------------------------------ A8R0S4_MACFA A8R0S4_MACFA ------------------------------------------------------------ Q4R547_MACFA Q4R547_MACFA ------------------------------------------------------------ K6PF_PONAB K6PF_PONAB ------------------------------------------------------------ B4E162_HUMAN B4E162_HUMAN ------------------------------------------------------------ Q5RAS3_PONAB Q5RAS3_PONAB ------------------------------------------------------------ Q7KYX9_HUMAN Q7KYX9_HUMAN ------------------------------------------------------------ Q6ZTT1_HUMAN Q6ZTT1_HUMAN LKDEFHLKFFMCVIQSRQLVRTPQRTAGEASTSSMLIPKPPPKTDILKSLDTMDDPDTVG Q96I60_HUMAN Q96I60_HUMAN ------------------------------------------------------------ K6PF_HUMAN K6PF_HUMAN ------------------------------------------------------------ Q90YA3_CHICK Q90YA3_CHICK ------------------------------------------------------------ B5DET9_XENTR B5DET9_XENTR ---------------------------------------------------------CRL Q6DD69_XENLA Q6DD69_XENLA -----------------------------------------MATLLNLEDFDEPETRPDT Q4RVW3_TETNG Q4RVW3_TETNG ------------------------------------------------------------ Q66HV8_DANRE Q66HV8_DANRE ------------------------------------------------------------ A4QNV1_DANRE A4QNV1_DANRE ------------------------------------------------------------ Q4RXY2_TETNG Q4RXY2_TETNG ------------------------------------------------------------ Q4RQP4_TETNG Q4RQP4_TETNG ------------------------------------------------------------ Q59GI2_HUMAN Q59GI2_HUMAN ------------------------------------------------------------ Q8AYP9_CHICK Q8AYP9_CHICK ------------------------------------------------------------ K6PL_BOVIN K6PL_BOVIN ------------------------------------------------------------ K6PL_RAT K6PL_RAT ------------------------------------------------------------ Q6P783_RAT Q6P783_RAT ------------------------------------------------------------ Q8CD98_MOUSE Q8CD98_MOUSE ------------------------------------------------------------ K6PL_MOUSE K6PL_MOUSE ------------------------------------------------------------ Q8VDX7_MOUSE Q8VDX7_MOUSE ------------------------------------------------------------ K6PL_PONAB K6PL_PONAB ------------------------------------------------------------ K6PL_HUMAN K6PL_HUMAN ------------------------------------------------------------ Q7L2M7_HUMAN Q7L2M7_HUMAN ------------------------------------------------------------ Q9BSP4_HUMAN Q9BSP4_HUMAN ------------------------------------------------------------ B3KNQ7_HUMAN B3KNQ7_HUMAN ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

Q4SNL3_TETNG Q4SNL3_TETNG --------------RKFFENLSGAGKSIAVLTSGGDAQVQAFRWCSGAETSVNPFSSSNQ Q4SKQ6_TETNG Q4SKQ6_TETNG ------------------------------------------------------------ Q5ZHU4_CHICK Q5ZHU4_CHICK ----------MDHQPKFFENLSGTGKAIGVLTSGGDAQ---------------------- Q6PF67_XENLA Q6PF67_XENLA ---------MAQPDKKLFENLSGKGKAIGVLTSGGDAQ---------------------- A2RV78_XENLA A2RV78_XENLA ---------MAQPDKRLFENLSGKGKAIGVLTSGGDAQ---------------------- Q6P4Y8_XENTR Q6P4Y8_XENTR ---------MAQPDRKLFENLSGKGKAIGVLTSGGDAQ---------------------- K6PP_RAT K6PP_RAT -MSDQDSSTSSTSFPKYLEHLSGDGKAIGVLTSGGDAQ---------------------- K6PP_MOUSE K6PP_MOUSE -MSDLDSS-SSSAYPKYLEHLSGDGKAIGVLTSGGDAQ---------------------- Q8C605_MOUSE Q8C605_MOUSE -MSDLDSS-SSSAYPKYLEHLSGDGKAIGVLTSGGDAQ---------------------- K6PP_RABIT K6PP_RABIT -MDNKVSASPRGSYRKFLEHLSGAGKAIGVLTSGGDAQ---------------------- K6PP_PONAB K6PP_PONAB -MDADDSRAPKGSLRKFLEHLSGAGKAIGVLTSGGDAQ---------------------- O14943_HUMAN O14943_HUMAN ------------------------------------------------------------ B3KS15_HUMAN B3KS15_HUMAN -MCGYERCRPCRGAHGYLRGGQGVLHLRGLPGHGGR------------------------ Q5VSR7_HUMAN Q5VSR7_HUMAN -MCGYERCRPCRGAHGYLRGGQGVLHLRGLPGHGGR------------------------ K6PP_HUMAN K6PP_HUMAN -MDADDSRAPKGSLRKFLEHLSGAGKAIGVLTSGGDAQ---------------------- Q5VSR8_HUMAN Q5VSR8_HUMAN -MDADDSRAPKGSLRKFLEHLSGAGKAIGVLTSGGDAQ---------------------- Q8WTZ9_HUMAN Q8WTZ9_HUMAN ------------------------------------------------------------ K6PF_RABIT K6PF_RABIT ----------MTHEEHHAARTLGVGKAIAVLTSGGDAQ---------------------- K6PF_HORSE K6PF_HORSE ----------MTHEEHHAAKTLGIGKAIAVLTSGGDAQ---------------------- K6PF_PIG K6PF_PIG ----------MTHEEHHAAKSLGVGKAIAVLTSGGDAQ---------------------- Q1HL06_PIG Q1HL06_PIG ------------------------------------------------------------ K6PF_BOVIN K6PF_BOVIN -----------MTHEHHAAKTLGIGKAIAVLTSGGDAQ---------------------- K6PF_CANFA K6PF_CANFA ----------MTHEEHHAAKTLGIGKAIAVLTSGGDAQ---------------------- Q1LZL7_MOUSE Q1LZL7_MOUSE ------------------------------------------------------------ K6PF_RAT K6PF_RAT ----------MTHEEHHEAKTLGIGKAIAVLTSGGDAQ---------------------- Q52KS1_RAT Q52KS1_RAT ----------MTHEEHHEAKTLGIGKAIAVLTSGGDAQ---------------------- Q99K08_MOUSE Q99K08_MOUSE ----------MTHEEHHAAKTLGIGKAIAVLTSGGDAQ---------------------- K6PF_MOUSE K6PF_MOUSE ----------MTHEEHHAAKTLGIGKAIAVLTSGGDAQ---------------------- K6PF_MACFA K6PF_MACFA ----------MTHEEHHAAKTLGIGKAIAVLTSGGDAQ---------------------- A8R0S4_MACFA A8R0S4_MACFA ------------------------------------------------------------ Q4R547_MACFA Q4R547_MACFA ----------MTHEEHHAAKTLGIGKAIAVLTSGGDAQ---------------------- K6PF_PONAB K6PF_PONAB ----------MTHEEHHATKTLGIGKAIAVLTSGGDAQ---------------------- B4E162_HUMAN B4E162_HUMAN ------------------------------------------------------------ Q5RAS3_PONAB Q5RAS3_PONAB ----------MTHEEHHAAKTLGIGKAIAVLTSGGDAQ---------------------- Q7KYX9_HUMAN Q7KYX9_HUMAN ------------------------------------------------------------ Q6ZTT1_HUMAN Q6ZTT1_HUMAN SIPVFKTEWIMTHEEHHAAKTLGIGKAIAVLTSGGDAQ---------------------- Q96I60_HUMAN Q96I60_HUMAN ------------HEEHHAAKTLGIGKAIAVLTSGGDAQ---------------------- K6PF_HUMAN K6PF_HUMAN ----------MTHEEHHAAKTLGIGKAIAVLTSGGDAQ---------------------- Q90YA3_CHICK Q90YA3_CHICK ---------------------MGAGKAIAVLTSGGDAQ---------------------- B5DET9_XENTR B5DET9_XENTR FCFSTDKTMLASRSKHHDAQTMGTGKAIAVLTSGGDAQ---------------------- Q6DD69_XENLA Q6DD69_XENLA SYYNTDKTMLPAGSKHHDAQTMGIGKAIAVLTSGGDAQ---------------------- Q4RVW3_TETNG Q4RVW3_TETNG --------MSANQPAAADPTKMGVGRSIAVLTSGGDAQ---------------------- Q66HV8_DANRE Q66HV8_DANRE --------MANINTTEVDPTKMGVGRAIAVLTSGGDAQ---------------------- A4QNV1_DANRE A4QNV1_DANRE ----------MQHSAPVDPTKMGVGRAIAVLTSGGDAQ---------------------- Q4RXY2_TETNG Q4RXY2_TETNG ------------------------------------------------------------ Q4RQP4_TETNG Q4RQP4_TETNG --------------------------------MDPDSQ---------------------- Q59GI2_HUMAN Q59GI2_HUMAN ------------------------------------------------------------ Q8AYP9_CHICK Q8AYP9_CHICK --------------------MAGAGMAIAVLTSGGDAQ---------------------- K6PL_BOVIN K6PL_BOVIN ----------MASVDLEKLRTTGAGKAIGVLTSGGDAQ---------------------- K6PL_RAT K6PL_RAT ----------MATVDLEKLRMSGAGKAIGVLTSGGDAQ---------------------- Q6P783_RAT Q6P783_RAT ----------MATVDLEKLRMSGAGKAIGVLTSGGDAQ---------------------- Q8CD98_MOUSE Q8CD98_MOUSE ------------------------------------------------------------ K6PL_MOUSE K6PL_MOUSE ----------MATVDLEKLRMSGAGKAIGVLTSGGDAQ---------------------- Q8VDX7_MOUSE Q8VDX7_MOUSE ----------MATVDLEKLRMSGAGKAIGVLTSGGDAQ---------------------- K6PL_PONAB K6PL_PONAB ----------MAAVDLEKLRASGAGKAIGVLTSGGDAQ---------------------- K6PL_HUMAN K6PL_HUMAN ----------MAAVDLEKLRASGAGKAIGVLTSGGDAQ---------------------- Q7L2M7_HUMAN Q7L2M7_HUMAN ------------------------------------------------------------ Q9BSP4_HUMAN Q9BSP4_HUMAN ------------------------------------------------------------ B3KNQ7_HUMAN B3KNQ7_HUMAN ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

Q4SNL3_TETNG Q4SNL3_TETNG PALLPRLACMNGAVRAVVRMGIYVGAKVYFIHEGYQGMVDGGNNIKEAKWE----SVSSM Q4SKQ6_TETNG Q4SKQ6_TETNG -------------------------------------MVDGGDNIREATWE----SVSSM Q5ZHU4_CHICK Q5ZHU4_CHICK --------GMNAAVRAVVRMGIYVKAKVYFVYEGYQGMVDGGDNIVEVSWE----SVSSI Q6PF67_XENLA Q6PF67_XENLA --------GMNAAVRAVVRMGIYVQAKVYFIYEGYQGMVDGGDNIEEVSWE----SVSSI A2RV78_XENLA A2RV78_XENLA --------GMNAAVRAVVRMGIYVQAKVYFIYEGYQGMVDGGDNIEEVSWE----SVSSI Q6P4Y8_XENTR Q6P4Y8_XENTR --------GMNAAVRAVVRMGIYVQAKVYFIYEGYQGMVDGGDNIEEVSWE----SVSSI K6PP_RAT K6PP_RAT --------GMNAAVRAVVRMGIYTGAKVYFIYEGYQGMVDGGSNIVEAKWE----CVSSI K6PP_MOUSE K6PP_MOUSE --------GMNAAVRAVVRMGIYTGAKVYFIYEGYQGLVDGGSNIVEAKWD----CVSSI Q8C605_MOUSE Q8C605_MOUSE --------GMNAAVRAVVRMGIYTGAKVYFIYEGYQGLVDGGSNIVEAKWD----CVSSI K6PP_RABIT K6PP_RABIT --------GMNAAVRAVVRMGIYVGAKVYFIYEGYQGMVDGGSNIVEANWE----SVSSI K6PP_PONAB K6PP_PONAB --------GMNAAVRAVVRMGIYVGAKVCFIYEGYQGMVDGGSNIAEADWE----SVSSI O14943_HUMAN O14943_HUMAN ------------------------------------------------------------ B3KS15_HUMAN B3KS15_HUMAN ------------------RLKHRRGRLGECLQHPASGAVRGDWREKPGCWSHRFPCPGRH Q5VSR7_HUMAN Q5VSR7_HUMAN ------------------RLKHRRGRLGECLQHPASGAVRGDWREKPGCWSHRFPCPGRH K6PP_HUMAN K6PP_HUMAN --------GMNAAVRAVVRMGIYVGAKVYFIYEGYQGMVDGGSNIAEADWE----SVSSI Q5VSR8_HUMAN Q5VSR8_HUMAN --------GMNAAVRAVVRMGIYVGAKVYFIYEGYQGMVDGGSNIAEADWE----SVSSI Q8WTZ9_HUMAN Q8WTZ9_HUMAN ------------------------------------------------------------ K6PF_RABIT K6PF_RABIT --------GMNAAVRAVVRVGIFTGARVFFVHEGYQGLVDGGDHIREATWE----SVSMM K6PF_HORSE K6PF_HORSE --------GMNAAVRAVVRVGIFTGARVFFVHEGYQGLVDGGDHIREATWE----SVSMM K6PF_PIG K6PF_PIG --------GMNAAVRAVVRVGIYTGARVFFVHEGYQGLVDGGDNIREATWE----SVSMM Q1HL06_PIG Q1HL06_PIG ----------------VVRVGIYTGARVFFVHEGYQGLVDGGDNIREATWE----SVSMM K6PF_BOVIN K6PF_BOVIN --------GMNAAVRAVVRVGIYTGARVFFVHEGYQGLVDGGDNIREATWE----SVSMM K6PF_CANFA K6PF_CANFA --------GMNAAVRAVVRVGIFTGARVFFVHEGYQGLVDGGDHIREATWE----SVSMM Q1LZL7_MOUSE Q1LZL7_MOUSE ----------------------------VQFHPGYRGLVDGGEHIREATWE----SVSMM K6PF_RAT K6PF_RAT --------GMNATVRAVVRVGIFTGLRVFFVHEGYQGLVDGGEHIREATWE----SVSMM Q52KS1_RAT Q52KS1_RAT --------GMNAAVRAVVRVGIFTGARVFFVHEGYQGLVDGGEHIREATWE----SVSMM Q99K08_MOUSE Q99K08_MOUSE --------GMNAAVRAVVRVGIFTGARVFFVHEGYQGLVDGGEHIREATWE----SVSMM K6PF_MOUSE K6PF_MOUSE --------GMNAAVRAVVRVGIFTGARVFFVHEGYQGLVDGGEHIREATWE----SVSMM K6PF_MACFA K6PF_MACFA --------GMNAAVRAVVRVGIFTGARVFFVHEGYQGLVDGGDNIKEATWE----SVSMM A8R0S4_MACFA A8R0S4_MACFA ------------------------------------------------------------ Q4R547_MACFA Q4R547_MACFA --------GMNAAVRAVVRVGIFTGARVFFVHEGYQGLVDGGDNIKEATWE----SVSMM K6PF_PONAB K6PF_PONAB --------GMNAAVRAVVRVGIFTGARVFFVHEGYQGLVDGGDHIKEATWE----SVSMM B4E162_HUMAN B4E162_HUMAN ------------------------------------------------------------ Q5RAS3_PONAB Q5RAS3_PONAB --------GMNAAVRAVVRVGIFTGARVFFVHEGYQGLVDGGDHIKEATWE----SVSMM Q7KYX9_HUMAN Q7KYX9_HUMAN ------------------------------------------------------------ Q6ZTT1_HUMAN Q6ZTT1_HUMAN --------GMNAAVRAVVRVGIFTGARVFFVHEGYQGLVDGGDHIKEATWE----SVSMM Q96I60_HUMAN Q96I60_HUMAN --------GMNAAVRAVVRVGIFTGARVFFVHEGYQGLVDGGDHIKEATWE----SVSMM K6PF_HUMAN K6PF_HUMAN --------GMNAAVRAVVRVGIFTGARVFFVHEGYQGLVDGGDHIKEATWE----SVSMM Q90YA3_CHICK Q90YA3_CHICK --------GMNAAVRAVVRVGIYTGAKVYFVHEGYQGLVDGGDNLKEATWE----SVSMM B5DET9_XENTR B5DET9_XENTR --------GMNAAVRAVVRVGIYTGAKVYFVHEGYQGLVDGGDNIKEATWE----SVSMM Q6DD69_XENLA Q6DD69_XENLA --------GMNAAVRAVVRVGIYTGAKVYFVHEGYQGLVDGGDNIKEASWE----SVSMM Q4RVW3_TETNG Q4RVW3_TETNG --------GMNAAVRATVRVGLYTGAKVYFVHEGYQGLVDGGERIRLATWE----SVSMM Q66HV8_DANRE Q66HV8_DANRE --------GMNAAVRATVRVGLYTGAKVFFVHEGYQGLVDGGDHIRPATWE----SVSMM A4QNV1_DANRE A4QNV1_DANRE --------GMNAAVRATVRVGIYTGAKVYFVHEGYQGLVDGGDNIRQATWE----SVSMM Q4RXY2_TETNG Q4RXY2_TETNG ------------------------------------------------------------ Q4RQP4_TETNG Q4RQP4_TETNG ---------------------------------GYQGLVDGGDNIKLAHWH----SVTNI Q59GI2_HUMAN Q59GI2_HUMAN ----------------------------------------------PASWA--------- Q8AYP9_CHICK Q8AYP9_CHICK --------GMNAAVRAVTRMGIYVGAKVFLIYEGYEGLVEGGDNIKQATWL----SVSNI K6PL_BOVIN K6PL_BOVIN --------GMNAAVRAVTRMGIYVGAKVFLIYEGYEGLVEGGENIKQANWL----SVSNI K6PL_RAT K6PL_RAT --------GMNAAVRAVTRMGIYVGAKVFLIYEGYEGLVEGGENIKPANWL----SVSNI Q6P783_RAT Q6P783_RAT --------GMNAAVRAVTRMGIYVGAKVFLIYEGYEGLVEGGENIKPANWL----SVSNI Q8CD98_MOUSE Q8CD98_MOUSE ------------------------------------------------------------ K6PL_MOUSE K6PL_MOUSE --------GMNAAVRAVTRMGIYVGAKVFLIYEGYEGLVEGGENIKPANWL----SVSNI Q8VDX7_MOUSE Q8VDX7_MOUSE --------GMNAAVRAVTRMGIYVGAKVFLIYEGYEGLVEGGENIKPANWL----SVSNI K6PL_PONAB K6PL_PONAB --------GMNAAVRAVTRMGIYVGAKVFLIHEGYEGLVEGGENIKQANWL----SVSNI K6PL_HUMAN K6PL_HUMAN --------GMNAAVRAVTRMGIYVGAKVFLIYEGYEGLVEGGENIKQANWL----SVSNI Q7L2M7_HUMAN Q7L2M7_HUMAN ------------------------------------------------------------ Q9BSP4_HUMAN Q9BSP4_HUMAN ------------------------------------------------------------ B3KNQ7_HUMAN B3KNQ7_HUMAN ------------------------------------------------------------ MATCH CONSENSUS ??????????????????????????????????????V?G????????W??????????

Q4SNL3_TETNG Q4SNL3_TETNG LQVGGTVIGSARCKEFRTREGRLKAAHNLVQRSITNLCVIGGDGSLTGANLFREEWSGLL Q4SKQ6_TETNG Q4SKQ6_TETNG LQVGGTVIGSARCKEFRTHEGRLKAAHNLVQRGITNLCVIGGDGSLTGANLFREEWSGLL Q5ZHU4_CHICK Q5ZHU4_CHICK LQVGGTVIGSARCKSFRTREGRLQAAYNLVRRGITNLCVIGGDGSLTGANLFREEWSGLL Q6PF67_XENLA Q6PF67_XENLA LQVGGTVIGSARCKSFRNREGRLQAACNLVQRGITNLCVIGGDGSLTGANLFREEWSGLL A2RV78_XENLA A2RV78_XENLA LQVGGTVIGSARCKSFRTREGRLQAANNLVQRGITNLCVIGGDGSLTGANLFREEWSGLL Q6P4Y8_XENTR Q6P4Y8_XENTR LQVGGTVIGSARCKAFRTREGRLQAAYNLVQRGITNLCVIGGDGSLTGANLFREEWSGLL K6PP_RAT K6PP_RAT LQVGGTIIGSARCQAFRSREGRLKAACNLVRLGITNLCVIGGDGSLTGANLFRKEWSGLL K6PP_MOUSE K6PP_MOUSE LQVGGTIIGSARCKAFRSREGRLKAACNLARLGITNLCVIGGDGSLTGANLFRKEWSGLL Q8C605_MOUSE Q8C605_MOUSE LQVGGTIIGSARCKAFRSREGRLKAACNLARLGITNLCVIGGDGSLTGANLFRKEWSGLL K6PP_RABIT K6PP_RABIT LQVGGTIIGSARSKAFRTREGRLKAACNLIHRGITNLCVIGGSGSLTGANIFRMEWSGLL K6PP_PONAB K6PP_PONAB LQVGGTIIGSARCQAFRTREGRLKAACNLLQRGITNLCVIGGDGSLTGANLFRKEWSGLL O14943_HUMAN O14943_HUMAN ------------------------------------------------------------ B3KS15_HUMAN B3KS15_HUMAN ALVGGTIIGSARCQAFRTREGRLKAACNLLQRGITNLCVIGGDGSLTGANLFRKEWSGLL Q5VSR7_HUMAN Q5VSR7_HUMAN ALVGGTIIGSARCQAFRTREGRLKAACNLLQRGITNLCVIGGDGSLTGANLFRKEWSGLL K6PP_HUMAN K6PP_HUMAN LQVGGTIIGSARCQAFRTREGRLKAACNLLQRGITNLCVIGGDGSLTGANLFRKEWSGLL Q5VSR8_HUMAN Q5VSR8_HUMAN LQVGGTIIGSARCQAFRTREGRLKAACNLLQRGITNLCVIGGDGSLTGANLFRKEWSGLL Q8WTZ9_HUMAN Q8WTZ9_HUMAN ------------------------------------------------------------ K6PF_RABIT K6PF_RABIT LQLGGTVIGSARCKDFREREGRLRAAHNLVKRGITNLCVIGGDGSLTGADTFRSEWSDLL K6PF_HORSE K6PF_HORSE LQLGGTVIGSARCKDFREREGRLRAAHNLVKLGITNLCVIGGDGSLTGADTFRSEWSDLL K6PF_PIG K6PF_PIG LQLGGTVIGSARCKDFREREGRLRAAHNLVKRGITNLCVIGGDGSLTGADTFRSEWGDLL Q1HL06_PIG Q1HL06_PIG LQLGGTVIGSARCKDLREREGRLRAAHNLVKRGITNLCVIGGDGSLTGADTFRSEWGDLL K6PF_BOVIN K6PF_BOVIN LQLGGTVIGSARCKDFREREGRLRAAHNLVKRGITNLCVIGGDGSLTGADTFRSEWSDLL K6PF_CANFA K6PF_CANFA LQLGGTVIGSARCKDFREREGRLRAAHNLVKRGITNLCVIGGDGSLTGADTFRSEWSDLL Q1LZL7_MOUSE Q1LZL7_MOUSE LQLGGTVIGSARCKDFREREGRLRAAHNLVKRGITNLCVIGGDGSLTGADTFRSEWSDLL K6PF_RAT K6PF_RAT LQLGGTVIGSARCKDFREREGRLRAAHNLVKRGITNLCVIGGDGSLTGADTFRSEWSDLL Q52KS1_RAT Q52KS1_RAT LQLGGTVIGSARCKDFREREGRLRAAHNLVKRGITNLCVIGGDGSLTGADTFRSEWSDLL Q99K08_MOUSE Q99K08_MOUSE LQLGGTVIGSARCKDFREREGRLRAAHNLVKRGITNLCVIGGDGSLTGADTFRSEWSDLL K6PF_MOUSE K6PF_MOUSE LQLGGTVIGSARCKDFREREGRLRAAHNLVKRGITNLCVIGGDGSLTGADTFRSEWSDLL K6PF_MACFA K6PF_MACFA LQLGGTVIGSARCKDFREREGRLRAAYNLVKRGITNLCVIGGDGSLTGADTFRSEWSELL A8R0S4_MACFA A8R0S4_MACFA ------------------------------------------------------------ Q4R547_MACFA Q4R547_MACFA LQLGGTVIGSARCKDFREREGRLRAAYNLVKRGITNLCVIGGDGSLTGADTFRSEWSDLL K6PF_PONAB K6PF_PONAB LQLGGTVIGSARCKDFREREGRLRAAYNLVKRGITNLCVIGGDGSLTGADTFRSEWSDLL B4E162_HUMAN B4E162_HUMAN ------------------------------------------------------------ Q5RAS3_PONAB Q5RAS3_PONAB LQLGGTVIGSARCKDFREREGRLRAAYNLVKRGITNLCVIGGDGSLTGADTFRSEWSDLL Q7KYX9_HUMAN Q7KYX9_HUMAN ------------------------------------------------------------ Q6ZTT1_HUMAN Q6ZTT1_HUMAN LQLGGTVIGSARCKDFREREGRLRAAYNLVKRGITNLCVIGGDGSLTGADTFRSEWSDLL Q96I60_HUMAN Q96I60_HUMAN LQLGGTVIGSARCKDFREREGRLRAAYNLVKRGITNLCVIGGDGSLTGADTFRSEWSDLL K6PF_HUMAN K6PF_HUMAN LQLGGTVIGSARCKDFREREGRLRAAYNLVKRGITNLCVIGGDGSLTGADTFRSEWSDLL Q90YA3_CHICK Q90YA3_CHICK LQLGGTVIGSARCQDFRTREGRLKAARNLVKRGITNLCVIGGDGSLTGADTFRAEWSSLL B5DET9_XENTR B5DET9_XENTR LQLGGTVIGSARCQDFRGREGRLKAACNLVKKGITNLCVIGGDGSLTGADTFRTEWSNLL Q6DD69_XENLA Q6DD69_XENLA LQLGGTVIGSARCQDFRGREGRLKAACNLVKKGITNLCVIGGDGSLTGADTFRSEWSGLL Q4RVW3_TETNG Q4RVW3_TETNG LQLGGTVIGSARCKDFRSREGRMKAAANLVKLGITNLCVIGGDGSLTGANEFRTEWSGLL Q66HV8_DANRE Q66HV8_DANRE LQLGGTVIGSARCKDFQTREGRLKAAYNLVKLGITNLCVIGGDGSLTGANIFRTEWSDLL A4QNV1_DANRE A4QNV1_DANRE LQLGGTVIGSARCQDFRTKEGRAKAACNLVKLGITNLCVIGGDGSLTGANEFRNEWSELL Q4RXY2_TETNG Q4RXY2_TETNG ------------------------------------------------------------ Q4RQP4_TETNG Q4RQP4_TETNG IQQGGTMIGTARCKAFTTRDGRLAAAFNLVKKGITNLCVCGGDGSLTGANIFRNEWSGLL Q59GI2_HUMAN Q59GI2_HUMAN ------------------------------------------------------------ Q8AYP9_CHICK Q8AYP9_CHICK IQLGGTVIGSARCKAFTTRQGRCAPARNLVEHGITNLCVIGGDGSLTGADVFRAEWAGLL K6PL_BOVIN K6PL_BOVIN IQLGGTVIGSARCKAFTTREGRRAAAYNLVQRGITNLCVIGGDGSLTGANIFRSEWGSLL K6PL_RAT K6PL_RAT IQLGGTIIGSARCKAFTTREGRLAAAYNLLQHGITNLCVIGGDGSLTGANIFRNEWGSLL Q6P783_RAT Q6P783_RAT IQLGGTIIGSARCKAFTTREGRLAAAYNLLQHGITNLCVIGGDGSLTGANIFRNEWGSLL Q8CD98_MOUSE Q8CD98_MOUSE ------------------------------------------------------------ K6PL_MOUSE K6PL_MOUSE IQLGGTIIGSARCKAFTTREGRLAAAYNLLQHGITNLCVIGGDGSLTGANIFRNEWGSLL Q8VDX7_MOUSE Q8VDX7_MOUSE IQLGGTIIGSARCKAFTTREGRLAAAYNLLQHGITNLCVIGGDGSLTGANIFRNEWGSLL K6PL_PONAB K6PL_PONAB IQLGGTVIGSARCKAFTTREGRRAAAYNLVQHGITNLCVIGGDGSLTGANIFRSEWGSLL K6PL_HUMAN K6PL_HUMAN IQLGGTIIGSARCKAFTTREGRRAAAYNLVQHGITNLCVIGGDGSLTGANIFRSEWGSLL Q7L2M7_HUMAN Q7L2M7_HUMAN ------------------------------------------------------------ Q9BSP4_HUMAN Q9BSP4_HUMAN ------------------------------------------------------------ B3KNQ7_HUMAN B3KNQ7_HUMAN ------------------------------------------------------------ MATCH CONSENSUS ???GGT?IG?AR????????GR???A?NL????ITNLCV?GG?GSLTGA??FR?EW??LL

Q4SNL3_TETNG Q4SNL3_TETNG DELLRTGLINEKEAQSNSELHIVGMVGSIDNDFCGTDMTIGTDSALHRIIEVVDAIMTTA Q4SKQ6_TETNG Q4SKQ6_TETNG TELVEQGLIEQDSIQKYSALHIVGMVGSIDNDFCGTDMTIGTDSALHRIIEVVDAIMTTA Q5ZHU4_CHICK Q5ZHU4_CHICK EELAQKGKIDEEAVKKYAYLNIVGMVGSIDNDFCGTDMTIGTDSALHRIIEVVDAIMTTA Q6PF67_XENLA Q6PF67_XENLA DELVQTGKIEAEAAKEYAHLNIVGMVGSIDNDFCGTDMTIGTDSALHRIMEVVDAIMTTA A2RV78_XENLA A2RV78_XENLA DELVQNGKIEAEATKQYAHLNIVGMVGSIDNDFCGTDMTIGTDSALHRIIEVVDAIMTTA Q6P4Y8_XENTR Q6P4Y8_XENTR DELMQNGKIEAEATREYAHLNIVGMVGSIDNDFCGTDMTIGTDSALHRIIEVVDAIMTTA K6PP_RAT K6PP_RAT EELAKNGEIDSDTVKKHAYLNVVGMVGSIDNDFCGTDMTIGTDSALHRIIEVVDAIMTTA K6PP_MOUSE K6PP_MOUSE EELARNGDIDNDTVQKYSYLNVVGMVGSIDNDFCGTDMTIGTDSALHRIIEVVDAIMTTA Q8C605_MOUSE Q8C605_MOUSE EELARNGDIDNDTVQKYSYLNVVGMVGSIDNDFCGTDMTIGTDSALHRIIEVVDAIMTTA K6PP_RABIT K6PP_RABIT EELAQDGKIDNEAVQKYAYLNVVGMVGSIDNDFCGTDMTIGTDSACHRIIEVIDAIMTTA K6PP_PONAB K6PP_PONAB EELARNGQIDKEAVQKYAYLNVVGMVGSIDNDFCGTDMTIGTDSALHRIIEVVDAIMTTA O14943_HUMAN O14943_HUMAN ------------------------------------------------------------ B3KS15_HUMAN B3KS15_HUMAN EELARNGQIDKEAVQKYAYLNVVGMVGSIDNDFCGTDMTIGTDSALHRIIEVVDAIMTTA Q5VSR7_HUMAN Q5VSR7_HUMAN EELARNGQIDKEAVQKYAYLNVVGMVGSIDNDFCGTDMTIGTDSALHRIIEVVDAIMTTA K6PP_HUMAN K6PP_HUMAN EELARNGQIDKEAVQKYAYLNVVGMVGSIDNDFCGTDMTIGTDSALHRIIEVVDAIMTTA Q5VSR8_HUMAN Q5VSR8_HUMAN EELARNGQIDKEAVQKYAYLNVVGMVGSIDNDFCGTDMTIGTDSALHRIIEVVDAIMTTA Q8WTZ9_HUMAN Q8WTZ9_HUMAN ------------------------------------------------------------ K6PF_RABIT K6PF_RABIT SDLQKAGKITAEEATRSSYLNIVGLVGSIDNDFCGTDMTIGTDSALHRITEIVDAITTTA K6PF_HORSE K6PF_HORSE SDLQKAGKITAEEATKSNYLNIVGLVGSIDNDFCGTDMTIGTDSALHRIIEIVDAITTTA K6PF_PIG K6PF_PIG NDLQKAGKITAEEANKSSYLNIVGLVGSIDNDFCGTDMTIGTDSALHRIIEIVDAITTTA Q1HL06_PIG Q1HL06_PIG NDLQKAGKITAEEANKSSYLNIVGLVGSIDNDFCGTDMTIGTDSALHRIIEIVDAITTTA K6PF_BOVIN K6PF_BOVIN SDLQKSGKITAEEATKSSYLNIVGLVGSIDNDFCGTDMTIGTDSALHRIIEIVDAITTTA K6PF_CANFA K6PF_CANFA SDLQKAGKITAEEATKSSYLNIVGLVGSIDNDFCGTDMTIGTDSALHRIIEIVDAITTTA Q1LZL7_MOUSE Q1LZL7_MOUSE NDLQKDGKITAEEATKSSYLNIVGLVGSIDNDFCGTDMTIGTDSALHRIVEIVDAITTTA K6PF_RAT K6PF_RAT NDLQKDGKITAEERTKSSYLNIVFLVGSIDNDFCGTDMTIGTDSALHRIVEIVDAITTTA Q52KS1_RAT Q52KS1_RAT NDLQKDGKITAEEATKSSYLNIVGLVGSIDNDFCGTDMTIGTDSALHRIVEIVDAITTTA Q99K08_MOUSE Q99K08_MOUSE NDFQKDGKITAEEATKSSYLNIVGLVGSIDNDFCGTDMTIGTDSALHRIVEIVDAITTTA K6PF_MOUSE K6PF_MOUSE NDLQKDGKITAEEATKSSYLNIVGLVGSIDNDFCGTDMTIGTDSALHRIVEIVDAITTTA K6PF_MACFA K6PF_MACFA GDLQKAGKITDEEATKSSYLNIVGLVGSIDNDFCGTDMTIGTDSALHRIIEIVDAITTTA A8R0S4_MACFA A8R0S4_MACFA ------------------------------------------------------------ Q4R547_MACFA Q4R547_MACFA GDLQKAGKITDEEATKSSYLNIVGLVGSIDNDFCGTDMTIGTDSALHRIIEIVDAITTTA K6PF_PONAB K6PF_PONAB SDLQKAGKITDEEATKSSYLNIVGLVGSIDNDFCGTDMTIGTDSALHRIIEIVDAITTTA B4E162_HUMAN B4E162_HUMAN -------------------------------------MTIGTDSALHRIMEIVDAITTTA Q5RAS3_PONAB Q5RAS3_PONAB SDLQKAGKITDEEATKSSYLNIVGLVGSIDNDFCGTDMTIGTDSALHRIIEIVDAITTTA Q7KYX9_HUMAN Q7KYX9_HUMAN ------------------------------------------------------------ Q6ZTT1_HUMAN Q6ZTT1_HUMAN SDLQKAGKITDEEATKSSYLNIVGLVGSIDNDFCGTDMTIGTDSALHRIMEIVDAITTTA Q96I60_HUMAN Q96I60_HUMAN SDLQKAGKITDEEATKSSYLNIVGLVGSIDNDFCGTDMTIGTDSALHRIMEIVDAITTTA K6PF_HUMAN K6PF_HUMAN SDLQKAGKITDEEATKSSYLNIVGLVGSIDNDFCGTDMTIGTDSALHRIMEIVDAITTTA Q90YA3_CHICK Q90YA3_CHICK AELLKTGGITAEEAKKSSHLNIVGMVGSIDNDFCGTDMTIGTDSALHRIMEIVDAITTTA B5DET9_XENTR B5DET9_XENTR ADLVKAGRITADESKKSSHLNIVGLVGSIDNDFCGTDMTIGTDSALHRIMEIVDAITTTA Q6DD69_XENLA Q6DD69_XENLA ADLVKADTITEDEAKKSSYLNIVGLVGSIDNDFCGTDMTIGTDSALHRIMEIVDAITTTA Q4RVW3_TETNG Q4RVW3_TETNG ADLVQAGRITEQEAKKSSHLNIVGMVGSIDNDFCGTDMTIGTDSALHRIIEVVDAITTTA Q66HV8_DANRE Q66HV8_DANRE KDHVSKGKITKEEAKASSHLNIVGMVGSIDNDFCGTDMTIGTDSALHRIIEVVDSITTTA A4QNV1_DANRE A4QNV1_DANRE QILQKAGKITAEEAKCSSHLNIVGMVGSIDNDFCGTDMTIGTDSALHRIMEVVDAITTTA Q4RXY2_TETNG Q4RXY2_TETNG ------------------------------------------------------------ Q4RQP4_TETNG Q4RQP4_TETNG AELVEKGRITDALAGQHQHLNIVGLVGSIDNDFCGTDMTIGADSALHRIMDIIDAIMTTA Q59GI2_HUMAN Q59GI2_HUMAN ------------------------------------------------------------ Q8AYP9_CHICK Q8AYP9_CHICK DELLRDGLISEEVAKANGRLNVVGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITTTA K6PL_BOVIN K6PL_BOVIN EELVSEGKISEGTAQTYSHLNIAGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITTTA K6PL_RAT K6PL_RAT EELVKEGKISESTAQNYAHLSIAGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITTTA Q6P783_RAT Q6P783_RAT EELVKEGKISESTAQNYAHLSIAGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITTTA Q8CD98_MOUSE Q8CD98_MOUSE ------------------------------------------------------------ K6PL_MOUSE K6PL_MOUSE EELVKEGKISESTAQNYAHLTIAGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITTTA Q8VDX7_MOUSE Q8VDX7_MOUSE EELVKEGKISESTAQNYAHLTIAGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITTTA K6PL_PONAB K6PL_PONAB EELVAEGKISETMARTYSHLNIAGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITTTA K6PL_HUMAN K6PL_HUMAN EELVAEGKISETTARTYSHLNIAGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITTTA Q7L2M7_HUMAN Q7L2M7_HUMAN ------------------------------------------------------------ Q9BSP4_HUMAN Q9BSP4_HUMAN ------------------------------------------------------------ B3KNQ7_HUMAN B3KNQ7_HUMAN ------------------------------------------------------------ MATCH CONSENSUS ????????I??????????L?????VGSIDNDFCGTDMTIGTDSALHRI?E??DAI?TTA

Q4SNL3_TETNG Q4SNL3_TETNG Q-------------SHQRTFVLEVMGRHCGYLALVSALACGADWVFIPEMPPSDGWEDSM Q4SKQ6_TETNG Q4SKQ6_TETNG Q-------------SHQRTFVLEVMGRHCGYLALVSALACGADWVLIPEMPPEDGWEDKM Q5ZHU4_CHICK Q5ZHU4_CHICK Q-------------SHQRTFVLEVMGRHCGYLALVSALACGADWVFIPEYPPEEGWEDSM Q6PF67_XENLA Q6PF67_XENLA L-------------SHQRTFVLEVMGRHCGYLALVSALACGADWMFIPESPPEEGWEDLM A2RV78_XENLA A2RV78_XENLA Q-------------SHQRTFVLEVMGRHCGYLALVSALACGADWVFIPEYPPEEGWEDTM Q6P4Y8_XENTR Q6P4Y8_XENTR Q-------------SHQRTFVLEVMGRHCGYLALVSALACGADWVFIPEYPPEEGWEDMM K6PP_RAT K6PP_RAT Q-------------SHQRTFVLEVMGRHCGYLALVSALACGADWVFLPESPPEEGWEEEM K6PP_MOUSE K6PP_MOUSE Q-------------SHQRTFVLEVMGRHCGYLALVSALTCGADWVFLPESPPEEDWEENM Q8C605_MOUSE Q8C605_MOUSE Q-------------SHQRTFVLEVMGRHCGYLALVSALTCGADWVFLPESPPEEDWEENM K6PP_RABIT K6PP_RABIT Q-------------SHQRTFVLEVMGRHCGYLALVSALACGADWVFLPESPPEEGWEEQM K6PP_PONAB K6PP_PONAB Q-------------SHQRTFVLEVMGRHCGYLALVSALACGADWVFLPESPPEEGWEEQM O14943_HUMAN O14943_HUMAN ------------------------------------------------------------ B3KS15_HUMAN B3KS15_HUMAN Q-------------SHQRTFVLEVMGRHCGYLALVSALACGADWVFLPESPPEEGWEEQM Q5VSR7_HUMAN Q5VSR7_HUMAN Q-------------SHQRTFVLEVMGRHCGYLALVSALACGADWVFLPESPPEEGWEEQM K6PP_HUMAN K6PP_HUMAN Q-------------SHQRTFVLEVMGRHCGYLALVSALACGADWVFLPESPPEEGWEEQM Q5VSR8_HUMAN Q5VSR8_HUMAN Q-------------SHQRTFVLEVMGRHCGYLALVSALACGADWVFLPESPPEEGWEEQM Q8WTZ9_HUMAN Q8WTZ9_HUMAN ------------------------------------------------------------ K6PF_RABIT K6PF_RABIT Q-------------SHQRTFVLEVMGRHCGYLALVTSLSCGADWVFIPECPPDDNWEDHL K6PF_HORSE K6PF_HORSE Q-------------SHQRTFVLEVMGRHCGYLALVTSLSCGADWVFIPECPPDDDWEDHL K6PF_PIG K6PF_PIG Q-------------SHQRTFVLEVMGRHCGYLALVTSLSCGADWVFIPECPPDDAWEEHL Q1HL06_PIG Q1HL06_PIG Q-------------SHQRTFVLEVMGRHCGYLALVTSLSCGADWVFIPECPPDDAWGEHL K6PF_BOVIN K6PF_BOVIN Q-------------SHQRTFVLEVMGRHCGYLALVTSLSCGADWVFIPECPPDDDWEEHL K6PF_CANFA K6PF_CANFA Q-------------SHQRTFVLEVMGRHCGYLALVTSLSCGADWVFIPECPPDDDWEEHL Q1LZL7_MOUSE Q1LZL7_MOUSE Q-------------SHQRTFVLEVMGRHCGYLALVTSLSCGADWVFIPECPPDDDWEEHL K6PF_RAT K6PF_RAT Q-------------SHQRTFVLEVMGRHCGYLALVTSLSCGADWVFIPECPPDDDWEEHL Q52KS1_RAT Q52KS1_RAT Q-------------SHQRTFVLEVMGRHCGYLALVTSLSCGADWVFIPECPPDDDWEEHL Q99K08_MOUSE Q99K08_MOUSE Q-------------SHQRTFVLEVMGRHCGYLALVTSLSCGADWVFIPECPPDDDWEEHL K6PF_MOUSE K6PF_MOUSE Q-------------SHQRTFVLEVMGRHCGYLALVTSLSCGADWVFIPECPPDDDWEEHL K6PF_MACFA K6PF_MACFA Q-------------SHQRTFVLEVMGRHCGYLALVTSLSCGADWVFIPECPPDDDWEEHL A8R0S4_MACFA A8R0S4_MACFA ------------------------------------------------------------ Q4R547_MACFA Q4R547_MACFA Q-------------SHQRTFVLEVMGRHCGYLALVTSLSCGADWVFIPECPPDDDWEEHL K6PF_PONAB K6PF_PONAB Q-------------SHQRTIVLEVMGRHCGYLALVTSLSCGADWVFIPECPPDDDWEEHL B4E162_HUMAN B4E162_HUMAN Q-------------SHQRTFVLEVMGRHCGYLALVTSLSCGADWVFIPECPPDDDWEEHL Q5RAS3_PONAB Q5RAS3_PONAB Q-------------SHQRTFVLEVMGRHCGYLALVTSLSCGADWVFIPECPPDDDWEEHL Q7KYX9_HUMAN Q7KYX9_HUMAN ------------------------------------------------------------ Q6ZTT1_HUMAN Q6ZTT1_HUMAN Q-------------SHQRTFVLEVMGRHCGYLALVTSLSCGADWVFIPECPPDDDWEEHL Q96I60_HUMAN Q96I60_HUMAN Q-------------SHQRTFVLEVMGRHCGYLALVTSLSCGADWVFIPECPPDDDWEEHL K6PF_HUMAN K6PF_HUMAN Q-------------SHQRTFVLEVMGRHCGYLALVTSLSCGADWVFIPECPPDDDWEEHL Q90YA3_CHICK Q90YA3_CHICK Q-------------SHQRTFVLEVMGRHCGYLALITSLACGADWVFIPESPPEDGWEDHL B5DET9_XENTR B5DET9_XENTR Q-------------SHQRTFVLEVMGRHCGYLALITALACGADWVFIPESPPEENWEEHL Q6DD69_XENLA Q6DD69_XENLA Q-------------SHQRTFVLEVMGRHCGYLALVTALACGADWVFVPESPPEENWEEHL Q4RVW3_TETNG Q4RVW3_TETNG Q-------------SHQRTFILEVMGRHCGYLALVTAQACGADWVFIPEMPPEHGWEDHL Q66HV8_DANRE Q66HV8_DANRE Q-------------SHQRAFILEVMGRHCGYLALVTALACGADWVFIPEMPPDDGWEEHL A4QNV1_DANRE A4QNV1_DANRE Q-------------SHQRAFILEVMGRHCGYLALVTALSCGADWVFIPEMPPDEGWEDHL Q4RXY2_TETNG Q4RXY2_TETNG -------------------------------------------------MPPEEGWEEHL Q4RQP4_TETNG Q4RQP4_TETNG QRSEGRGQQPAQSVCHQRTFVLEVMGRHCGYLALVSALASGADWLFIPEAPPKEGWEDHM Q59GI2_HUMAN Q59GI2_HUMAN ----------------------------------LSRLRCG--------CTP---WR--- Q8AYP9_CHICK Q8AYP9_CHICK Q-------------SHQRTFVLEVMGRHCGYLALVSGLASGADWLFIPESPPEDGWEDLM K6PL_BOVIN K6PL_BOVIN Q-------------SHQRTFVLEVMGRHCGYLALVSALASGADWLFIPEAPPEDGWENFM K6PL_RAT K6PL_RAT Q-------------SHQRTFVLEVMGRHCGYLALVSALASGADWLFIPEAPPEDGWENFM Q6P783_RAT Q6P783_RAT Q-------------SHQRTFVLEVMGRHCGYLALVSALASGADWLFIPEAPPEDGWENFM Q8CD98_MOUSE Q8CD98_MOUSE ------------------------------------------------------------ K6PL_MOUSE K6PL_MOUSE Q-------------SHQRTFVLEVMGRHCGYLALVSALASGADWLFIPEAPPEDGWENFM Q8VDX7_MOUSE Q8VDX7_MOUSE Q-------------SHQRTFVLEVMGRHCGYLALVSALASGADWLFIPEAPPEDGWENFM K6PL_PONAB K6PL_PONAB Q-------------SHQRTFVLEVMGRRCGYLALVSALASGADWLFIPEAPPEDGWENFM K6PL_HUMAN K6PL_HUMAN Q-------------SHQRTFVLEVMGRHCGYLALVSALASGADWLFIPEAPPEDGWENFM Q7L2M7_HUMAN Q7L2M7_HUMAN -----------------------------GYLALVSALASGADWLFIPEAPPEDGWENFM Q9BSP4_HUMAN Q9BSP4_HUMAN ------------------------------------------------------------ B3KNQ7_HUMAN B3KNQ7_HUMAN ------------------------------------------------------------ MATCH CONSENSUS Q?????????????SHQR?F?LEVMGRHCGYLALV??L??GADW?F?PE?PP???WE???

Q4SNL3_TETNG Q4SNL3_TETNG CQKLS--------ENRAERKRL-----NIIIVAEGAIDC-------HNKAITPDYIKD-- Q4SKQ6_TETNG Q4SKQ6_TETNG CQKLS--------ATRSRGTRL-----NIIIVAEGAIDR-------HGKPITSSFVKDFR Q5ZHU4_CHICK Q5ZHU4_CHICK CVKLS--------ENRARKKRL-----NIIIVAEGAIDC-------HNKPITSEKVKD-- Q6PF67_XENLA Q6PF67_XENLA CNKLS--------ENRARKKRL-----NIIIVSEGAIDC-------HNKPITSDLVKD-- A2RV78_XENLA A2RV78_XENLA CNKLS--------ENRARKKRL-----NIIIVSEGAIDC-------HNKPITSDLVKD-- Q6P4Y8_XENTR Q6P4Y8_XENTR CNKLS--------ENRARKKRL-----NIIIVSEGAIDC-------HNKAITSDMVKD-- K6PP_RAT K6PP_RAT CLKLS--------ENRARKKRL-----NIIIVSEGAIDT-------QNKPITSEKIKE-- K6PP_MOUSE K6PP_MOUSE CLKLS--------ENRARKKRL-----NIIIVSEGAIDM-------QNKPITSEKIKE-- Q8C605_MOUSE Q8C605_MOUSE CLKLS--------ENRARKKRL-----NIIIVSEGAIDM-------QNKPITSEKIKE-- K6PP_RABIT K6PP_RABIT CVKLS--------ENRAQKKRL-----NIIIVAEGAIDT-------LNRPITSEKIKE-- K6PP_PONAB K6PP_PONAB CVKLS--------ENRARKKRL-----NIIIVAEGAIDT-------QNKPITSEKIKE-- O14943_HUMAN O14943_HUMAN ------------------------------------------------------------ B3KS15_HUMAN B3KS15_HUMAN CVKLS--------ENRARKKRL-----NIIIVAEGAIDT-------QNKPITSEKIKE-- Q5VSR7_HUMAN Q5VSR7_HUMAN CVKLS--------ENRARKKRL-----NIIIVAEGAIDT-------QNKPITSEKIKE-- K6PP_HUMAN K6PP_HUMAN CVKLS--------ENRARKKRL-----NIIIVAEGAIDT-------QNKPITSEKIKE-- Q5VSR8_HUMAN Q5VSR8_HUMAN CVKLS--------ENRARKKRL-----NIIIVAEGAIDT-------QNKPITSEKIKE-- Q8WTZ9_HUMAN Q8WTZ9_HUMAN ------------------------------------------------------------ K6PF_RABIT K6PF_RABIT CRRLS--------ETRTRGSRL-----NIIIVAEGAIDR-------NGKPITSEGVKD-- K6PF_HORSE K6PF_HORSE CRRLS--------ETRTRGSRL-----NIIIVAEGAIDR-------NGKPITSESIKD-- K6PF_PIG K6PF_PIG CRRLS--------ETRTRGSRL-----NIIIVAEGAIDK-------NGQLITSENIKD-- Q1HL06_PIG Q1HL06_PIG CRRLS--------ETRTRGSRL-----NIIIVAEGAIDK-------NGQPITSENIKD-- K6PF_BOVIN K6PF_BOVIN CRRLS--------ETRNRGSRL-----NIIIVAEGAIDK-------NGKPITSEDIKN-- K6PF_CANFA K6PF_CANFA CRRLS--------ETRTRGSRL-----NIIIVAEGAIDK-------NGKPITSEEIKE-- Q1LZL7_MOUSE Q1LZL7_MOUSE CRRLS--------ETRTRGSRL-----NIIIVAEGAIDK-------NGKPITSEDIKN-- K6PF_RAT K6PF_RAT CRRLS--------ETRTRGSRL-----NIIIVAEGAIDK-------NGKPITSEDIKN-- Q52KS1_RAT Q52KS1_RAT CRRLS--------ETRTRGSRL-----NIIIVAEGAIDK-------NGKPITSEDIKN-- Q99K08_MOUSE Q99K08_MOUSE CRRLS--------ETRTRGSRL-----NIIIVAEGAIDK-------NGKPITSEDIKN-- K6PF_MOUSE K6PF_MOUSE CRRLS--------ETRTRGSRL-----NIIIVAEGAIDK-------NGKPITSEDIKN-- K6PF_MACFA K6PF_MACFA CRRLS--------ETRTRGSRL-----NIIIVAEGAIDR-------NGKPITSEDIKN-- A8R0S4_MACFA A8R0S4_MACFA ------------------------------------------------------------ Q4R547_MACFA Q4R547_MACFA CRRLS--------ETRTRGSRL-----NIIIVAEGAIDR-------NGKPITSEDIKN-- K6PF_PONAB K6PF_PONAB CRRLS--------ETRTRGSRL-----NIIIVAEGAIDK-------NGKPITSEDIKN-- B4E162_HUMAN B4E162_HUMAN CRRLS--------ETRTRGSRL-----NIIIVAEGAIDK-------NGKPITSEDIKN-- Q5RAS3_PONAB Q5RAS3_PONAB CRRLS--------ETRTRGSRL-----NIIIVAEGAIDK-------NGKPITSEDIKN-- Q7KYX9_HUMAN Q7KYX9_HUMAN ------------------------------------------------------------ Q6ZTT1_HUMAN Q6ZTT1_HUMAN CRRLS--------ETRTRGSRL-----NIIIVAEGAIDK-------NGKPITSEDIKN-- Q96I60_HUMAN Q96I60_HUMAN CRRLS--------ETRTRGSRL-----NIIIVAEGAIDK-------NGKPITSEDIKN-- K6PF_HUMAN K6PF_HUMAN CRRLS--------ETRTRGSRL-----NIIIVAEGAIDK-------NGKPITSEDIKN-- Q90YA3_CHICK Q90YA3_CHICK CRP-T--------ETRLGGSRL-----NIIIVAEGAIDR-------HGKAITSDDVKD-- B5DET9_XENTR B5DET9_XENTR CRRLS--------ETRGRGSRL-----NIIIVAEGAIDL-------NGKPITSDLVKD-- Q6DD69_XENLA Q6DD69_XENLA CRRLS--------ETRGRGSRL-----NIIIVAEGAIDL-------HGKPITSDLIKD-- Q4RVW3_TETNG Q4RVW3_TETNG CRRLADPGLSSQRDHRGRGRHVQRRQTNHVRPDQEAGDRQAGLRHPHHRFGTRAEGRD-- Q66HV8_DANRE Q66HV8_DANRE CRRLT--------ETRNAGSRL-----NVIIVAEGAINK-------EGQPITCDQLKD-- A4QNV1_DANRE A4QNV1_DANRE CRRLT--------YQRSIGNRL-----NVIIVAEGALDR-------HGKPITCDIIKN-- Q4RXY2_TETNG Q4RXY2_TETNG CRRLS--------DQRGRGSRL-----NIIIVAEGAMDR-------HGKPITCEQVKQ-- Q4RQP4_TETNG Q4RQP4_TETNG CSRLE--------GSRTTGSRL-----NIIIIAEGAIDM-------NGKPISSTYVKD-- Q59GI2_HUMAN Q59GI2_HUMAN CRAVH------------------------------------------------------- Q8AYP9_CHICK Q8AYP9_CHICK CERLG--------ETRSRGSRL-----NIIIIAEGAIDR-------NGKPISSNYVKD-- K6PL_BOVIN K6PL_BOVIN CERLG--------ETRSRGSRL-----NIIIIAEGAIDR-------NGKPISSRYVKD-- K6PL_RAT K6PL_RAT CERLG--------ETRSRGSRL-----NIIIIAEGAIDR-------HGKPISSSYVKD-- Q6P783_RAT Q6P783_RAT CERLG--------ETRSRGSRL-----NIIIIAEGAIDR-------HGKPISSSYVKD-- Q8CD98_MOUSE Q8CD98_MOUSE ------------------------------------------------------------ K6PL_MOUSE K6PL_MOUSE CERLG--------ETRSRGSRL-----NIIIIAEGAIDR-------HGKPISSSYVKD-- Q8VDX7_MOUSE Q8VDX7_MOUSE CERLG--------ETRSRGSRL-----NIIIIAEGAIDR-------HGKPISSSYVKD-- K6PL_PONAB K6PL_PONAB CERLG--------ETRSRGSRL-----NIIIIAEGAIDR-------DGKPISSSYVKD-- K6PL_HUMAN K6PL_HUMAN CERLG--------ETRSRGSRL-----NIIIIAEGAIDR-------NGKPISSSYVKD-- Q7L2M7_HUMAN Q7L2M7_HUMAN CERLG--------ETRSRGSRL-----NIIIIAEGAIDR-------NGKPISSSYVKD-- Q9BSP4_HUMAN Q9BSP4_HUMAN ------------------------------------------------------------ B3KNQ7_HUMAN B3KNQ7_HUMAN ------------------------------------------------------------ MATCH CONSENSUS C??L???????????R????RL?????NIII??EGAID????????????I?????K???

Q4SNL3_TETNG Q4SNL3_TETNG ------------------------------------------------------------ Q4SKQ6_TETNG Q4SKQ6_TETNG SCLATMLLKAQNRAGKKRLNVIIVAEGAIDRSNTPITTDYIKDVSTELCVRVWRFPHLGC Q5ZHU4_CHICK Q5ZHU4_CHICK ------------------------------------------------------------ Q6PF67_XENLA Q6PF67_XENLA ------------------------------------------------------------ A2RV78_XENLA A2RV78_XENLA ------------------------------------------------------------ Q6P4Y8_XENTR Q6P4Y8_XENTR ------------------------------------------------------------ K6PP_RAT K6PP_RAT ------------------------------------------------------------ K6PP_MOUSE K6PP_MOUSE ------------------------------------------------------------ Q8C605_MOUSE Q8C605_MOUSE ------------------------------------------------------------ K6PP_RABIT K6PP_RABIT ------------------------------------------------------------ K6PP_PONAB K6PP_PONAB ------------------------------------------------------------ O14943_HUMAN O14943_HUMAN ------------------------------------------------------------ B3KS15_HUMAN B3KS15_HUMAN ------------------------------------------------------------ Q5VSR7_HUMAN Q5VSR7_HUMAN ------------------------------------------------------------ K6PP_HUMAN K6PP_HUMAN ------------------------------------------------------------ Q5VSR8_HUMAN Q5VSR8_HUMAN ------------------------------------------------------------ Q8WTZ9_HUMAN Q8WTZ9_HUMAN ------------------------------------------------------------ K6PF_RABIT K6PF_RABIT ------------------------------------------------------------ K6PF_HORSE K6PF_HORSE ------------------------------------------------------------ K6PF_PIG K6PF_PIG ------------------------------------------------------------ Q1HL06_PIG Q1HL06_PIG ------------------------------------------------------------ K6PF_BOVIN K6PF_BOVIN ------------------------------------------------------------ K6PF_CANFA K6PF_CANFA ------------------------------------------------------------ Q1LZL7_MOUSE Q1LZL7_MOUSE ------------------------------------------------------------ K6PF_RAT K6PF_RAT ------------------------------------------------------------ Q52KS1_RAT Q52KS1_RAT ------------------------------------------------------------ Q99K08_MOUSE Q99K08_MOUSE ------------------------------------------------------------ K6PF_MOUSE K6PF_MOUSE ------------------------------------------------------------ K6PF_MACFA K6PF_MACFA ------------------------------------------------------------ A8R0S4_MACFA A8R0S4_MACFA ------------------------------------------------------------ Q4R547_MACFA Q4R547_MACFA ------------------------------------------------------------ K6PF_PONAB K6PF_PONAB ------------------------------------------------------------ B4E162_HUMAN B4E162_HUMAN ------------------------------------------------------------ Q5RAS3_PONAB Q5RAS3_PONAB ------------------------------------------------------------ Q7KYX9_HUMAN Q7KYX9_HUMAN ------------------------------------------------------------ Q6ZTT1_HUMAN Q6ZTT1_HUMAN ------------------------------------------------------------ Q96I60_HUMAN Q96I60_HUMAN ------------------------------------------------------------ K6PF_HUMAN K6PF_HUMAN ------------------------------------------------------------ Q90YA3_CHICK Q90YA3_CHICK ------------------------------------------------------------ B5DET9_XENTR B5DET9_XENTR ------------------------------------------------------------ Q6DD69_XENLA Q6DD69_XENLA ------------------------------------------------------------ Q4RVW3_TETNG Q4RVW3_TETNG ------------------------------------------------------------ Q66HV8_DANRE Q66HV8_DANRE ------------------------------------------------------------ A4QNV1_DANRE A4QNV1_DANRE ------------------------------------------------------------ Q4RXY2_TETNG Q4RXY2_TETNG ------------------------------------------------------------ Q4RQP4_TETNG Q4RQP4_TETNG ------------------------------------------------------------ Q59GI2_HUMAN Q59GI2_HUMAN ------------------------------------------------------------ Q8AYP9_CHICK Q8AYP9_CHICK ------------------------------------------------------------ K6PL_BOVIN K6PL_BOVIN ------------------------------------------------------------ K6PL_RAT K6PL_RAT ------------------------------------------------------------ Q6P783_RAT Q6P783_RAT ------------------------------------------------------------ Q8CD98_MOUSE Q8CD98_MOUSE ------------------------------------------------------------ K6PL_MOUSE K6PL_MOUSE ------------------------------------------------------------ Q8VDX7_MOUSE Q8VDX7_MOUSE ------------------------------------------------------------ K6PL_PONAB K6PL_PONAB ------------------------------------------------------------ K6PL_HUMAN K6PL_HUMAN ------------------------------------------------------------ Q7L2M7_HUMAN Q7L2M7_HUMAN ------------------------------------------------------------ Q9BSP4_HUMAN Q9BSP4_HUMAN ------------------------------------------------------------ B3KNQ7_HUMAN B3KNQ7_HUMAN ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

Q4SNL3_TETNG Q4SNL3_TETNG ------------LVVSRLGFDTRVTILGHVQRGGTPSAFDRI------LASRMGVEAVLA Q4SKQ6_TETNG Q4SKQ6_TETNG LLCDLYHCTAALLVVKNLGFDTRVTILGHVQRGGTPSAFDRI------LASRMGVEAVLA Q5ZHU4_CHICK Q5ZHU4_CHICK ------------LVVQRLGFDTRVTILGHVQRGGTPSAFDRI------LASRMGVEAVLA Q6PF67_XENLA Q6PF67_XENLA ------------LVVKRLGFDTRVTILGHVQRGGTPSAFDRI------LASRMGVDCVLA A2RV78_XENLA A2RV78_XENLA ------------LVMKRLGFDTRVTILGHVQRGGTPSAFDRI------LASRMGVDCVLA Q6P4Y8_XENTR Q6P4Y8_XENTR ------------LVVKRLGFDTRVTILGHVQRGGTPSAFDRI------LASRMGVDCVLA K6PP_RAT K6PP_RAT ------------LVVTNLGFDTRVTILGHVQRGGTPSAFDRI------LASRMGVEAVLA K6PP_MOUSE K6PP_MOUSE ------------LVVKNLGFDTRVTILGHVQRGGTPSAFDRI------LASRMGVEAVIA Q8C605_MOUSE Q8C605_MOUSE ------------LVVKNLGFDTRVTILGHVQRGGTPSAFDRI------LASRMGVEAVIA K6PP_RABIT K6PP_RABIT ------------LVVTQLGYDTRVTILGHVQRGGTPSAFDRI------LASRMGVEAVLA K6PP_PONAB K6PP_PONAB ------------LVVTQLGYDTRVTILGHVQRGGTPSAFDRI------LASRMGVEAVIA O14943_HUMAN O14943_HUMAN ------------------------------------------------------------ B3KS15_HUMAN B3KS15_HUMAN ------------LVVTQLGYDTRVTILGHVQRGGTPSAFDRI------LASRMGVEAVIA Q5VSR7_HUMAN Q5VSR7_HUMAN ------------LVVTQLGYDTRVTILGHVQRGGTPSAFDRI------LASRMGVEAVIA K6PP_HUMAN K6PP_HUMAN ------------LVVTQLGYDTRVTILGHVQRGGTPSAFDRI------LASRMGVEAVIA Q5VSR8_HUMAN Q5VSR8_HUMAN ------------LVVTQLGYDTRVTILGHVQRGGTPSAFDRI------LASRMGVEAVIA Q8WTZ9_HUMAN Q8WTZ9_HUMAN ------------------------------------------------------------ K6PF_RABIT K6PF_RABIT ------------LVVRRLGYDTRVTVLGHVQRGGTPSAFDRI------LGSRMGVEAVMA K6PF_HORSE K6PF_HORSE ------------LVVKRLGYDTRVTVLGHVQRGGTPSAFDRI------LGSRMGVEAVMA K6PF_PIG K6PF_PIG ------------LVVKRLGYDTRVTVLGHVQRGGTPSAFDRI------LGSRMGVEAVMA Q1HL06_PIG Q1HL06_PIG ------------LVVKRLGYDTRVTVLGHVQRGGTPSAFDRI------LGSRMGVEAVMA K6PF_BOVIN K6PF_BOVIN ------------LVVKRLGYDTRVTVLGHVQRGGTPSAFDRI------LGSRMGVEAVMA K6PF_CANFA K6PF_CANFA ------------LVVKRLGYDTRVTVLGHVQRGGTPSAFDRI------LGSRMGVEAVMA Q1LZL7_MOUSE Q1LZL7_MOUSE ------------LVVKRLGYDTRVTVLGHVQRGGTPSAFDRI------LGSRMGVEAVMA K6PF_RAT K6PF_RAT ------------LVVKRLGYDTRVTVLGHVQRGGTPSAFDRI------LGSRMGVEAVMA Q52KS1_RAT Q52KS1_RAT ------------LVVKRLGYDTRVTVLGHVQRGGTPSAFDRI------LGSRMGVEAVMA Q99K08_MOUSE Q99K08_MOUSE ------------LVVKRLGYDTRVTVLGHVQRGGTPSAFDRI------LGSRMGVEAVMA K6PF_MOUSE K6PF_MOUSE ------------LVVKRLGYDTRVTVLGHVQRGGTPSAFDRI------LGSRMGVEAVMA K6PF_MACFA K6PF_MACFA ------------LVVKRLGYDTRVTVLGHVQRGGTPSAFDRI------LGSRMGVEAVMA A8R0S4_MACFA A8R0S4_MACFA ----------------------------------------------------MGVEAVMA Q4R547_MACFA Q4R547_MACFA ------------LVVKRLGYDARVTVLGHVQRGGTPSAFDRI------LGSRMGVEAVMA K6PF_PONAB K6PF_PONAB ------------LVVKRLGYDTRVTVLGHVQRGGTPSAFDRI------LGSRMGVEAVMA B4E162_HUMAN B4E162_HUMAN ------------LVVKRLGYDTRVTVLGHVQRGGTPSAFDRI------LGSRMGVEAVMA Q5RAS3_PONAB Q5RAS3_PONAB ------------LVVKRLGYDTRVTVLGHVQRGGTPSAFDRI------LGSRMGVEAVMA Q7KYX9_HUMAN Q7KYX9_HUMAN ----------------------------------------------------MGVEAVMA Q6ZTT1_HUMAN Q6ZTT1_HUMAN ------------LVVKRLGYDTRVTVLGHVQRGGTPSAFDRI------LGSRMGVEAVMA Q96I60_HUMAN Q96I60_HUMAN -------------------------------------------------GSRMGVEAVMA K6PF_HUMAN K6PF_HUMAN ------------LVVKRLGYDTRVTVLGHVQRGGTPSAFDRI------LGSRMGVEAVMA Q90YA3_CHICK Q90YA3_CHICK ------------LVVKRLGYDTRVTILGHVQRGGTPSAFDRI------LGSRMGVEAVMA B5DET9_XENTR B5DET9_XENTR ------------LVVKRLGYDTRVTVLGHVQRGGTPSAFDRI------LGSRMGVEAVMA Q6DD69_XENLA Q6DD69_XENLA ------------LVIKRLGYDTRVTVLGHVQRGGTPSAFDRI------LGSRMGVEAVMA Q4RVW3_TETNG Q4RVW3_TETNG ------------AVGVRQNPGESLGGATNREAGAEQTQEPPV----SPQGSRMGVEAVMA Q66HV8_DANRE Q66HV8_DANRE ------------LVTKRLGFDTRATILGHVQRGGTPSAFDRV------LGSRMGVEAVMA A4QNV1_DANRE A4QNV1_DANRE ------------LVTKKLGFDTRATILGHVQRGGTPSAFDRI------LGSRMGVEAVMA Q4RXY2_TETNG Q4RXY2_TETNG ------------LVSKKLGFDTRTTILGHVQRGGTPSAFDRILVNQTFLPSRMGVEAVMA Q4RQP4_TETNG Q4RQP4_TETNG ------------LVVKRLGYDTRLTVLGHVQRGGTPSAFDRI------LSSRLGIEAVIA Q59GI2_HUMAN Q59GI2_HUMAN ------------------------------------------------------------ Q8AYP9_CHICK Q8AYP9_CHICK ------------LVVQRLGFDTRVTVLGHVQRVGTPSAFDRV------LSSKMGMEAVMA K6PL_BOVIN K6PL_BOVIN ------------LVVQRLGFDTRVTVLGHVQRGGTPSAFDRI------LSSKMGMEAVMA K6PL_RAT K6PL_RAT ------------LVVQRLGFDTRVTVLGHVQRGGTPSAFDRV------LSSKMGMEAVMA Q6P783_RAT Q6P783_RAT ------------LVVQRLGFDTRVTVLGHVQRGGTPSAFDRV------LSSKMGMEAVMA Q8CD98_MOUSE Q8CD98_MOUSE ----------------------------------------------------MGMEAVMA K6PL_MOUSE K6PL_MOUSE ------------LVVQRLGFDTRVTVLGHVQRGGTPSAFDRI------LSSKMGMEAVMA Q8VDX7_MOUSE Q8VDX7_MOUSE ------------LVVQRLGFDTRVTVLGHVQRGGTPSAFDRI------LSSKMGMEAVMA K6PL_PONAB K6PL_PONAB ------------LVVQRLGFDTRVTVLGHVQRGGTPSAFDRV------LSSKMAMEAVMA K6PL_HUMAN K6PL_HUMAN ------------LVVQRLGFDTRVTVLGHVQRGGTPSAFDRI------LSSKMGMEAVMA Q7L2M7_HUMAN Q7L2M7_HUMAN ------------LVVQRLGFDTRVTVLGHVQRGGTPSAFDRI------LSSKMGMEAVMA Q9BSP4_HUMAN Q9BSP4_HUMAN -------------------------VLGHVQRGGTPSAFDRI------LSSKMGMEAVMA B3KNQ7_HUMAN B3KNQ7_HUMAN ------------------------------------------------------------ MATCH CONSENSUS ????????????LV???LG?DTR?T?LGHVQRGGTPSAFDR???????L?S?MG?EAV?A

Q4SNL3_TETNG Q4SNL3_TETNG LLEASATTPACVVSLVGNQAVRLPLMECVQMTQEVQKAMDEKKFEEAVRLRGRSFENNLV Q4SKQ6_TETNG Q4SKQ6_TETNG LLETTANTPACVVSLCGNQSVRLPLMECVEMTQEVQKAMDEKRFEEAVKLRGRSFENNLK Q5ZHU4_CHICK Q5ZHU4_CHICK LLEATPDTPACVVSLSGNQAVRLPLMECVQMTQEVQKAMDEGRFVEAVRLRGRSFENNLN Q6PF67_XENLA Q6PF67_XENLA LLEATPETPACVVSLCGNQAVRLPLMECVQMTQEVQKAMDERRFEDAVRLRGRSFENNLN A2RV78_XENLA A2RV78_XENLA LLEATPETPACVVSLCGNQAVRLPLMECVQMTQEVQKAMDERRFDDAVRLRGRSFENNLN Q6P4Y8_XENTR Q6P4Y8_XENTR LLEATPETPACVVSLCGNQAVRLPLMECVQMTQEVQKAMDERRFDDAVRLRGRSFENNLN K6PP_RAT K6PP_RAT LLEATPETPACVVSLRGNQAVRLPLMECVQMTQDVQKAMDERRFDEAVKLRGRSFEGNLN K6PP_MOUSE K6PP_MOUSE LLEATPETPACVVSLRGNQAVRLPLMECVQMTQDVQKAMDERRFKEAVKLRGRRFEGNLN Q8C605_MOUSE Q8C605_MOUSE LLEATPETPACVVSLRGNQAVRLPLMECVQMTQDVQKAMDERRFKEAVKLRGRRFEGNLN K6PP_RABIT K6PP_RABIT LLEATPETPACVVSLSGNHAVRLPLVECVQMTQEVQKAMDERRFKDAVQLRGRSFENNLN K6PP_PONAB K6PP_PONAB LLEATPDTPACVVSLNGNHAVRLPLMECVQMTQDVQKAMDERRFQDAVRLRGRSFAGNLN O14943_HUMAN O14943_HUMAN ----------------------------------------ERRFQDAVRLRGRSFAGNLN B3KS15_HUMAN B3KS15_HUMAN LLEATPDTPACVVSLNGNHAVRLPLMECVQMTQDVQKAMDERRFQDAVRLRGRSFAGNLN Q5VSR7_HUMAN Q5VSR7_HUMAN LLEATPDTPACVVSLNGNHAVRLPLMECVQMTQDVQKAMDERRFQDAVRLRGRSFAGNLN K6PP_HUMAN K6PP_HUMAN LLEATPDTPACVVSLNGNHAVRLPLMECVQMTQDVQKAMDERRFQDAVRLRGRSFAGNLN Q5VSR8_HUMAN Q5VSR8_HUMAN LLEATPDTPACVVSLNGNHAVRLPLMECVQMTQDVQKAMDERRFQDAVRLRGRSFAGNLN Q8WTZ9_HUMAN Q8WTZ9_HUMAN -----GDTPACVVSLNGNHAVRLPLMECVQMTQDVQKAMDERRFQDAVRLRGRSFAGNLN K6PF_RABIT K6PF_RABIT LLEGTPDTPACVVSLSGNQAVRLPLMECVQVTKDVTKAMDEKRFDEAMKLRGRSFMNNWE K6PF_HORSE K6PF_HORSE LLEATPDTPACVVSLSGNQAVRLPLMECVQVTKDVTKAMAERKFDEAMKLRGRSFMNNWE K6PF_PIG K6PF_PIG LLEGTPDTPACVVSLSGNQAVRLPLMECVQVTKDVTKAMNEKRFDEAMKLRGRSFMNNWE Q1HL06_PIG Q1HL06_PIG LLEGTPDTPACVVSLSGNQAVRLPLMECVQVTKDVTKAMNEKRFDEAMKLRGRSFMNNWE K6PF_BOVIN K6PF_BOVIN LLEGTPDTPACVVSLSGNQAVRLPLMECVQVTKDVTRAMDERRFDEALKLRGRSFMNNWE K6PF_CANFA K6PF_CANFA LLEGTPDTPACVVSLSGNQAVRLPLMECVQVTKDVTKAMNDRKFDEAMKLRGRSFMNNWE Q1LZL7_MOUSE Q1LZL7_MOUSE LLEGTPDTPACVVSLSGNQ----------------------------------------- K6PF_RAT K6PF_RAT LLEGTPDTPACVVSLSGNTAVRLPLMECVQVTKDVTKAMDEKRFDEAIKLRGRSFMNNWE Q52KS1_RAT Q52KS1_RAT LLEGTPDTPACVVSLSGNQAVRLPLMECVQVTKDVTKAMDEKRFDEAIKLRGRSFMNNWE Q99K08_MOUSE Q99K08_MOUSE LLEGTPDTPACVVSLSGNQAVRLPLMECVQVTKDVTKAMDEKRFDEAIKLRGRSFMNNWE K6PF_MOUSE K6PF_MOUSE LLEGTPDTPACVVSLSGNQAVRLPLMECVQVTKDVTKAMDEKRFDEAIKLRGRSFMNNWE K6PF_MACFA K6PF_MACFA LLEGTPDTPACVVSLSGNQAVRLPLMECVQVTKDVTKAMEEKKFDEALKLRGRSFMNNWE A8R0S4_MACFA A8R0S4_MACFA LLEGTPDTPACVVSLSGNQAVRLPLMECVQVTKDVTKAMEEKKFDEALKLRGRSFMNNWE Q4R547_MACFA Q4R547_MACFA LLEGTPDTPACVVSLSGNQAVRLPLMECVQVTKDVTKAMEEKKFDEALKLRGRSFMNNWE K6PF_PONAB K6PF_PONAB LLEGTPDTPACVVSLSGNQAVRLPLMECVQVTKDVTKAMDEKKFDEALKLRGRSFMNNWE B4E162_HUMAN B4E162_HUMAN LLEGTPDTPACVVSLSGNQAVRLPLMECVQVTKDVTKAMDEKKFDEALKLRGRSFMNNWE Q5RAS3_PONAB Q5RAS3_PONAB LLEGTPDTPACVVSLSGNQAVRLPLMECVQVTKDVTKAMDEKKFDEALKLRGRSFMNNWE Q7KYX9_HUMAN Q7KYX9_HUMAN LLEGTPDTPACVVSLSGNQAVRLPLMECVQVTKDVTKAMDEKKFDEALKLRGRSFMNNWE Q6ZTT1_HUMAN Q6ZTT1_HUMAN LLEGTPDTPACVVSLSGNQAVRLPLMECVQVTKDVTKAMDEKKFDEALKLRGRSFMNNWE Q96I60_HUMAN Q96I60_HUMAN LLEGTPDTPACVVSLSGNQAVRLPLMECVQVTKDVTKAMDEKKFDEALKLRGRSFMNNWE K6PF_HUMAN K6PF_HUMAN LLEGTPDTPACVVSLSGNQAVRLPLMECVQVTKDVTKAMDEKKFDEALKLRGRSFMNNWE Q90YA3_CHICK Q90YA3_CHICK LLEGTPDTPACVVSLSGNQAVRLPLMECVQVTKDVTTAMNERRFDDAVKLRGRSFQNNWN B5DET9_XENTR B5DET9_XENTR LLEGTPDTPACVVSLSGNQAIRLPLMECVQVTKDVTQAMTEKRFDEALKLRGRSFENNWK Q6DD69_XENLA Q6DD69_XENLA LLEGTPDTPACVVSLSGNQAIRLPLMECVQVTKEVTQAMNEKKFEEALKLRGKSFENNWK Q4RVW3_TETNG Q4RVW3_TETNG LLEATPDTPACVVSLSGNQAVRLPLMECVQVTKDVTAAMAEGRFEDAVKLRGKSFENNWN Q66HV8_DANRE Q66HV8_DANRE LLEATPETPACVVSLTGNQAVRLPLMECVQVTKDVTIAMNEGRFDDAVKLRGRSFENNWN A4QNV1_DANRE A4QNV1_DANRE LLEATPDTPACVVSLSGNMAVRLPLMECVQVTKEVTKAMAEGRFEEAIKLRGKSFENNWN Q4RXY2_TETNG Q4RXY2_TETNG LLEATPDTPACVVSLSGNMAVRLPLMECVQV----------------------------- Q4RQP4_TETNG Q4RQP4_TETNG LMEASPDTPACVIGLSGNQAVRLPLMECVEMTKLVQKAMQERRFDEAVKLRGGSFENNWN Q59GI2_HUMAN Q59GI2_HUMAN ---------------------------------------------GVTRIPSRSFENNWN Q8AYP9_CHICK Q8AYP9_CHICK LLEATPDTPACVVSLSGNQSVRLPLMECVQVTKDVQKAMDEKRFDEAIQLRGRSFENNWN K6PL_BOVIN K6PL_BOVIN LLEATPDTPACVVSLSGNQSVRLPLMECVQMTKEVQKAMDEKRFDEAIQLRGGSFENNWN K6PL_RAT K6PL_RAT LLEATPDTPACVVSLSGNQSVRLPLMECVQVTKDVQKAMDEKRFDEAIQLRGRSFENNWK Q6P783_RAT Q6P783_RAT LLEATPDTPACVVSLSGNQSVRLPLMECVQVTKDVQKAMDEKRFDEAIQLRGRSFENNWK Q8CD98_MOUSE Q8CD98_MOUSE LLEATPDTPACVVSLSGNQSVRLPLMECVQVTKDVQKAMDEERFDEAIQLRGRSFENNWK K6PL_MOUSE K6PL_MOUSE LLEATPDTPACVVSLSGNQSVRLPLMECVQVTKDVQKAMDEERFDEAIQLRGRSFENNWK Q8VDX7_MOUSE Q8VDX7_MOUSE LLEATPDTPACVVSLSGNQSVRLPLMECVQVTKDVQKAMDEERFDEAIQLRGRSFENNWK K6PL_PONAB K6PL_PONAB LLEATHDTPACVVTLSGNQSVRLPLMECVQMTKEVQKAMDDKRFDEAIQLRGGSFENNWN K6PL_HUMAN K6PL_HUMAN LLEATPDTPACVVTLSGNQSVRLPLMECVQMTKEVQKAMDDKRFDEATQLRGGSFENNWN Q7L2M7_HUMAN Q7L2M7_HUMAN LLEATPDTPACVVTLSGNQSVRLPLMECVQMTKEVQKAMDDKRFDEATQLRGGSFENNWN Q9BSP4_HUMAN Q9BSP4_HUMAN LLEATPDTPACVVTLSGNQSVRLPLMECVQMTKEVQKAMDDKRFDEATQLRGGSFENNWN B3KNQ7_HUMAN B3KNQ7_HUMAN ------------------------------------------------------------ MATCH CONSENSUS LLE?TP?TPACVVSL?GN??VRLPLMECVQ?T??V?KAM?E??F??A??LRG?SF??N??

Q4SNL3_TETNG Q4SNL3_TETNG TYRLLSFRKTDSELPSSS---FNVAVLNVGAPAAGMNAAVRSAVRVGIAEGHRMFAVNDG Q4SKQ6_TETNG Q4SKQ6_TETNG TYKLLAHRKPESDLPHSN---FNVAVLNVGAPAAGMNAAVRSAVRVGISEGHKMFAVSDG Q5ZHU4_CHICK Q5ZHU4_CHICK TYKLLSQKKPDAELPKSN---FNVAVLNVGAPAAGMNAAVRAAVRVGITEGHKMFAVIDG Q6PF67_XENLA Q6PF67_XENLA TYKLLSHKKNISELPKSN---FNVAVLNVGAPAAGMNAAVRSAVRVGITEGHKMFAVNDG A2RV78_XENLA A2RV78_XENLA TYKLLSHKKNVSELPKSN---FNVAVLNVGAPAAGMNAAVRSAVRVGITEGHKMFAVNDG Q6P4Y8_XENTR Q6P4Y8_XENTR TYKLLSHKKNVADLPKSN---FTVAVLNVGAPAAGMNAAVRSAVRVGITEGHKMLAVNDG K6PP_RAT K6PP_RAT TYKRLAIKEPDDKIPKSN---CNVAIINVGAPAAGMNAAVRSAVRVGIAEGHKMFAIYDG K6PP_MOUSE K6PP_MOUSE TYKRLAIKLPDEKIVKSN---CNVAVINVGAPAAGMNAAVRSAVRVGIADGHKMFAIYDG Q8C605_MOUSE Q8C605_MOUSE TYKRLAIKLPDEKIVKSN---CNVAVINVGAPAAGMNAAVRSAVRVGIADGHKMFAIYDG K6PP_RABIT K6PP_RABIT TYKRLAIKLPDDKIQKSN---CNVAVINVGAPAAGMNAAVRSAVRVGIADGHKMFAVYDG K6PP_PONAB K6PP_PONAB TYKRLAIKLPDDQIPKTN---CNVAVINVGAPAAGMNAAVRSAVRVGIADGHRMLAIYDG O14943_HUMAN O14943_HUMAN TYKRLAIKLPDDQIPKTN---CNVAVINVGAPAAGMNAGVRSAVRVGIADGHRMLAIYDG B3KS15_HUMAN B3KS15_HUMAN TYKRLAIKLPDDQIPKTN---CNVAVINVGAPAAGMNAAVRSAVRVGIADGHRMLAIYDG Q5VSR7_HUMAN Q5VSR7_HUMAN TYKRLAIKLPDDQIPKTN---CNVAVINVGAPAAGMNAAVRSAVRVGIADGHRMLAIYDG K6PP_HUMAN K6PP_HUMAN TYKRLAIKLPDDQIPKTN---CNVAVINVGAPAAGMNAAVRSAVRVGIADGHRMLAIYDG Q5VSR8_HUMAN Q5VSR8_HUMAN TYKRLAIKLPDDQIPKTN---CNVAVINVGAPAAGMNAAVRSAVRVGIADGHRMLAIYDG Q8WTZ9_HUMAN Q8WTZ9_HUMAN TYKRLAIKLPDDQIPKTN---CNVAVINVGAPAAGMNAAVRSAVRVGIADGHRMLAIYDG K6PF_RABIT K6PF_RABIT VYKLLAHIRPPAP--KSG--SYTVAVMNVGAPAAGMNAAVRSTVRIGLIQGNRVLVVHDG K6PF_HORSE K6PF_HORSE VYKLLAHIRPPVS--KSG--SHTVAVMNVGAPAAGMNAAVRSTVRIGLIQGNRVLVVHDG K6PF_PIG K6PF_PIG VYKLLAHVRPPVT--KSG--SYTVAVMNVGAPTAGMNAAVRSTVRIGLIQGNRVLVVHDG Q1HL06_PIG Q1HL06_PIG VYKLLAHVRPPVT--KSG--SYTVAVMNVGAPAAGMNAAVRSTVRIGLIQGNRVLVVHDG K6PF_BOVIN K6PF_BOVIN VYKLLAHVRPPKS--KSG--SHTVAVMNVGAPAAGMNAAVRSTVRIGLIQGNRMLVVHDG K6PF_CANFA K6PF_CANFA VYKLLAHIRPPVS--KTSATMHTVAVMNVGAPAAGMNAAVRSTVRIGLIQGNRVLVVHDG Q1LZL7_MOUSE Q1LZL7_MOUSE ------------------------------------------------------------ K6PF_RAT K6PF_RAT VYKLLAHVRPPVS--KGG--LHTVAVMNVGAPAAGMNAAVRSTVRIGLIQGNRVLVVHDG Q52KS1_RAT Q52KS1_RAT VYKLLAHVRPPVS--KGG--LHTVAVMNVGAPAAGMNAAVRSTVRIGLIQGNRVLVVHDG Q99K08_MOUSE Q99K08_MOUSE VYKLLAHVRPPVS--KGG--LHTVAVMNVGAPAAGMNAAVRSTVRIGLIQGNRVLVVHDG K6PF_MOUSE K6PF_MOUSE VYKLLAHVRPPVS--KGG--LHTVAVMNVGAPAAGMNAAVRSTVRIGLIQGNRVLVVHDG K6PF_MACFA K6PF_MACFA VYKLLAHVRPPVS--KSG--SHTVAVMNVGAPAAGMNAAVRSTVRIGLIQGNRVLVVHDG A8R0S4_MACFA A8R0S4_MACFA VYKLLAHVRPPVS--KSG--SHTVAVMNVGAPAAGMNAAVRSTVRIGLIQGNRVLVVHDG Q4R547_MACFA Q4R547_MACFA VYKLLAHVRPPVS--KSG--SHTVAVMNVGAPAAGMNAAVRSTVRIGLIQGNRVLVVHDG K6PF_PONAB K6PF_PONAB VYKLLAHVRPPVS--KSG--SHTVAVMNVGAPAAGMNAAVRSTVRIGLIQGNRVLVVHDG B4E162_HUMAN B4E162_HUMAN VYKLLAHVRPPVS--KSG--SHTVAVMNVGAPAAGMNAAVRSTVRIGLIQGNRVLVVHDG Q5RAS3_PONAB Q5RAS3_PONAB VYKLLAHVRPPVS--KSG--SHTVAVMNVGAPAAGMNAAVRSTVRIGLIQGNRVLVVHDG Q7KYX9_HUMAN Q7KYX9_HUMAN VYKLLAHVRPPVS--KSG--SHTVAVMNVGAPAAGMNAAVRSTVRIGLIQGNRVLVVHDG Q6ZTT1_HUMAN Q6ZTT1_HUMAN VYKLLAHVRPPVS--KSG--SHTVAVMNVGAPAAGMNAAVRSTVRIGLIQGNRVLVVHDG Q96I60_HUMAN Q96I60_HUMAN VYKLLAHVRPPVS--KSG--SHTVAVMNVGAPAAGMNAAVRSTVRIGLIQGNRVLVVHDG K6PF_HUMAN K6PF_HUMAN VYKLLAHVRPPVS--KSG--SHTVAVMNVGAPAAGMNAAVRSTVRIGLIQGNRVLVVHDG Q90YA3_CHICK Q90YA3_CHICK VYKLLAHIRPPST--KSG---HTLAVLNVGAPAAGMNAAVRSTVRIGLIHGHRMLAVHDG B5DET9_XENTR B5DET9_XENTR VYRTLAHVRPTAT--KSG---YNLAILNVGAPAAGMNAAVRSTVRIGIIQGHTMFAVHDG Q6DD69_XENLA Q6DD69_XENLA VYRTLAHIRPPSA--KSG---YNLAVLNVGAPAAGMNAAVRSTVRIGIIQGHRMFAVHDG Q4RVW3_TETNG Q4RVW3_TETNG TYKLLAHINPPDV--KSN---INMAIMNIGAPCAGMNAAVRAAVRMGIIQGHNMLAVHDG Q66HV8_DANRE Q66HV8_DANRE TYKLLAHIRPPDK--KSN---INVAILNVGAPCAGMNAAVRAAVRIGIIQGHNMLAVHDG A4QNV1_DANRE A4QNV1_DANRE TYKLLAHVTAPDV--KSN---INIAILNVGAPCAGMNAAVRSAVRIGILQGHNMLAVHDG Q4RXY2_TETNG Q4RXY2_TETNG ----------------SN---INIALLNVGAPCAGMNAVVRSAVRIGILQGHQMLAVHDG Q4RQP4_TETNG Q4RQP4_TETNG IYKLLAYQKPVQT--ETK---FTVAILNVGAPAGGMNAAVRSAARLAIIHGHKVYGVHDG Q59GI2_HUMAN Q59GI2_HUMAN IYKLLAHQKPPKE--KSN---FSLAILNVGAPAAGMNAAVRSAVRTGISHGHTVYVVHDG Q8AYP9_CHICK Q8AYP9_CHICK IYKLLAHQKPAQE--KSP---FSLAILNVGAPAAGMNAAVRSAVRISICRGHTIYAVSDG K6PL_BOVIN K6PL_BOVIN IYKLLSHQKISKE--KTN---FSLAILNVGAPAAGMNAAVRSAVRSGISQGHTVYVVHDG K6PL_RAT K6PL_RAT IYKLLAHQKVSKE--KSN---FSLAILNVGAPAAGMNAAVRSAVRTGISEGHTVYVVHDG Q6P783_RAT Q6P783_RAT IYKLLAHQKVSKE--KSN---FSLAILNVGAPAAGMNAAVRSAVRTGISEGHTVYVVHDG Q8CD98_MOUSE Q8CD98_MOUSE IYKLLAHQKVSKE--KSN---FSLAILNVGAPAAGMNAAVRSAVRTGISEGHTVYIVHDG K6PL_MOUSE K6PL_MOUSE IYKLLAHQKVSKE--KSN---FSLAILNVGAPAAGMNAAVPSAVRTGISEGHTVYIVHDG Q8VDX7_MOUSE Q8VDX7_MOUSE IYKLLAHQKVSKE--KSN---FSLAILNVGAPAAGMNAAVRSAVRTGISEGHTVYIVHDG K6PL_PONAB K6PL_PONAB IYKLLAHQKPPKE--KSN---FSLAILNVGAPAAGMNAAVRSAVRTGISHGHTVYVVHDG K6PL_HUMAN K6PL_HUMAN IYKLLAHQKPPKE--KSN---FSLAILNVGAPAAGMNAAVRSAVRTGISHGHTVYVVHDG Q7L2M7_HUMAN Q7L2M7_HUMAN IYKLLAHQKPPKE--KSN---FSLAILNVGAPAAGMNAAVRSAVRTGISHGHTVYVVHDG Q9BSP4_HUMAN Q9BSP4_HUMAN IYKLLAHQKPPKE--KSN---FSLAILNVGAPAAGMNAAVRSAVRTGISHGHTVYVVHDG B3KNQ7_HUMAN B3KNQ7_HUMAN -----------------------------------MNAAVRSAVRTGISHGHTVYVVHDG MATCH CONSENSUS ?YK?LA?????????K????????A??NVGAPAAGMNAAVRS?VR?G???G?????V?DG

Q4SNL3_TETNG Q4SNL3_TETNG FEGLSKG--------------QIKEIKWGDVGGWTGQGGSLLGTKRLL------------ Q4SKQ6_TETNG Q4SKQ6_TETNG FEGFYKG--------------QIKEIKWADVGGWTGQGGSLLGTKRTLPAKHVDKIAAQM Q5ZHU4_CHICK Q5ZHU4_CHICK FEGFARG--------------KIKEISWGDVGGWTGQGGSILGTKRTLPAKYLEKIADQM Q6PF67_XENLA Q6PF67_XENLA FEGFAKG--------------QIKEIKWGGVGGWTGQGGSLLGTKRTLPAKYFDQIAEQI A2RV78_XENLA A2RV78_XENLA FEGFAKG--------------QIKEIKWGDVGGYTGQGGSLLGTKRTLPAKYFDQIAEQL Q6P4Y8_XENTR Q6P4Y8_XENTR FEGFAKG--------------QIKDIKWGDVGGWTGQGGSLLGTKRTLPAKYFDKIAEQI K6PP_RAT K6PP_RAT FDGLANG--------------QIKEIGWGDVGGWTGQGGSILGTKRTLPGKYLEKIAEQM K6PP_MOUSE K6PP_MOUSE FEGFANG--------------QIKEIGWADVGGWTGQGGSILGTKRTLPGKYLEKIAEQM Q8C605_MOUSE Q8C605_MOUSE FEGFANG--------------QIKEIGWADVGGWTGQGGSILGTKRTLPGKYLEKIAEQM K6PP_RABIT K6PP_RABIT FDGFAKG--------------QIKEIRWGDVGGWTGQGGSILGTKRILPGKYLEEIATQI K6PP_PONAB K6PP_PONAB FDGFAKG--------------QIKEIGWTDVGGWTGQGGSILGTKRVLPGKYLEEIATQM O14943_HUMAN O14943_HUMAN FDGFAKG--------------QIKEIGWTDVGGWTGQGGSILGTKRVLPGKYLEEIATQM B3KS15_HUMAN B3KS15_HUMAN FDGFAKG--------------QIKEIGWTDVGGWTGQGGSILGTKRVLPGKYLEEIATQM Q5VSR7_HUMAN Q5VSR7_HUMAN FDGFAKG--------------QIKEIGWTDVGGWTGQGGSILGTKRVLPGKYLEEIATQM K6PP_HUMAN K6PP_HUMAN FDGFAKG--------------QIKEIGWTDVGGWTGQGGSILGTKRVLPGKYLEEIATQM Q5VSR8_HUMAN Q5VSR8_HUMAN FDGFAKG--------------QIKEIGWTDVGGWTGQGGSILGTKRVLPGKYLEEIATQM Q8WTZ9_HUMAN Q8WTZ9_HUMAN FDGFAKG--------------QIKEIGWTDVGGWTGQGGSILGTKRVLPGKYLEEIATQM K6PF_RABIT K6PF_RABIT FEGPAKG--------------QIEEAGWSYVGGWTGQGGSKLGSKRTLPKKSFEQISANI K6PF_HORSE K6PF_HORSE FEGLAKG--------------RIEEAGWSYVGGWTGQGGSKLGTKRTLPRKSFEQISANI K6PF_PIG K6PF_PIG FEGLAKG--------------QIEEAGWSYVGGWTGQGGSKLGTKRTLPKKSFEQISANI Q1HL06_PIG Q1HL06_PIG FEGLAKG--------------QIEEAGWSYVGGWTGQGGSKLGTKRTLPKKSFEQISANI K6PF_BOVIN K6PF_BOVIN FEGLAKG--------------QIEEAGWSYVGGWTGQGGSKLGTKRTLPKKSFEQISANI K6PF_CANFA K6PF_CANFA FEGLAKG--------------QIEEAGWSYVGGWTGQGGSKLGTKRTLPKKSFEQISANI Q1LZL7_MOUSE Q1LZL7_MOUSE ------------------------------------------------------------ K6PF_RAT K6PF_RAT FEGLAKG--------------QIEEAGWSYVGGWTGQGGSKLGTKRTLPKKNLEQISANI Q52KS1_RAT Q52KS1_RAT FEGLAKG--------------QIEEAGWSYVGGWTGQGGSKLGTKRTLPKKNLEQISANI Q99K08_MOUSE Q99K08_MOUSE FEGLAKG--------------QIEEAGWSYVGGWTGQGGSKLGTKRTLPKKNLEQISANI K6PF_MOUSE K6PF_MOUSE FEGLAKG--------------QIEEAGWSYVGGWTGQGGSKLGTKRTLPKKNLEQISANI K6PF_MACFA K6PF_MACFA FEGLAKG--------------QIEEAGWSYVGGWTGQGGSKLGTKRTLPKKSFEQISANI A8R0S4_MACFA A8R0S4_MACFA FEGLAKG--------------QIEEAGWSYVGGWTGQGGSKLGTKRTLPKKSFEQISANI Q4R547_MACFA Q4R547_MACFA FEGLAKG--------------QIEEAGWSYVGGWTGQGGSKLGTKRTLPKKSFEQISANI K6PF_PONAB K6PF_PONAB FEGLAKG--------------QIEEAGWSYVGGWTGQGGSKLGTKRTLPKKSFEQISANI B4E162_HUMAN B4E162_HUMAN FEGLAKG--------------QIEEAGWSYVGGWTGQGGSKLGTKRTLPKKSFEQISANI Q5RAS3_PONAB Q5RAS3_PONAB FEGLAKG--------------QIEEAGWSYVGGWTGQGGSKLGTKRTLPKKSFEQISANI Q7KYX9_HUMAN Q7KYX9_HUMAN FEGLAKG--------------QIEEAGWSYVGGWTGQGGSKLGTKRTLPKKSFEQISANI Q6ZTT1_HUMAN Q6ZTT1_HUMAN FEGLAKG--------------QIEEAGWSYVGGWTGQGGSKLGTKRTLPKKSFEQISANI Q96I60_HUMAN Q96I60_HUMAN FEGLAKG--------------QIEEAGWSYVGGWTGQGGSKLGTKRTLPKKSFEQISANI K6PF_HUMAN K6PF_HUMAN FEGLAKG--------------QIEEAGWSYVGGWTGQGGSKLGTKRTLPKKSFEQISANI Q90YA3_CHICK Q90YA3_CHICK FEGLALG--------------KVEDISWDMVGGWTGLGGSKLGTKRTLPKKYFEEISATI B5DET9_XENTR B5DET9_XENTR FEGLAKG--------------QLEEIGWSGVGGWTGQGGSRLGTKRTLPKKYFEDISNTI Q6DD69_XENLA Q6DD69_XENLA FEGLAKG--------------QIEEIGWSGVGGWTGQGGSRLGTKRTLPKKYFEEISNNI Q4RVW3_TETNG Q4RVW3_TETNG FDGLAQGQVPLLWSPVMLMFPQIEPIGWTSVSGWTGKGGSMLGTKRSLPGKMLEEISQNI Q66HV8_DANRE Q66HV8_DANRE FEGLAQA--------------KIEPITWNTVGDWTGKGGSDLGTKRLLPGKYMEEISLNI A4QNV1_DANRE A4QNV1_DANRE FEGLANG--------------TIEPMAWGYVGGWTGKGGSILGTKRSLPANMIEEISLNI Q4RXY2_TETNG Q4RXY2_TETNG FDGLAQG--------------MIEPISWSGVAGWTGKGGSFLGTKRSLPEDVMEEISLNI Q4RQP4_TETNG Q4RQP4_TETNG FQGLARG--------------ELFKMEWKNVAGWTGQGGSLLGTKRTLPNEHMESVVETI Q59GI2_HUMAN Q59GI2_HUMAN FEGLAKG--------------QVQEVGWHDVAGWLGRGGSMLGTKRTLPKGQLESIVENI Q8AYP9_CHICK Q8AYP9_CHICK FEGLAKG--------------QIREVGWHDVAGWLGRGGSMLGTKRTLPKTCMEKIVENV K6PL_BOVIN K6PL_BOVIN FEGLAKN--------------QVQEVSWHDVAGWLGRGGSMLGTKRTLPKGFMEKIVENI K6PL_RAT K6PL_RAT FEGLAKG--------------QVQEVGWHDVAGWLGRGGSMLGTKRTLPKPHLEAIVENL Q6P783_RAT Q6P783_RAT FEGLAKG--------------QVQEVGWHDVAGWLGRGGSMLGTKRTLPKPHLEAIVENL Q8CD98_MOUSE Q8CD98_MOUSE FEGLAKG--------------QVQEVGWHDVAGWLGRGGSMLGTKRTLPKPHLEAIVENL K6PL_MOUSE K6PL_MOUSE FEGLAKG--------------QVQEVGWHDVAGWLGRGGSMLGTKRTLPKPHLEAIVENL Q8VDX7_MOUSE Q8VDX7_MOUSE FEGLAKG--------------QVQEVGWHDVAGWLGRGGSMLGTKRTLPKPHLEAIVENL K6PL_PONAB K6PL_PONAB FEGLAKG--------------QVQEVGWHDVAGWLGRGGSMLGTKRTLPKGQLESIVENI K6PL_HUMAN K6PL_HUMAN FEGLAKG--------------QVQEVGWHDVAGWLGRGGSMLGTKRTLPKGQLESIVENI Q7L2M7_HUMAN Q7L2M7_HUMAN FEGLAKG--------------QVQEVGWHDVAGWLGRGGSMLGTKRTLPKGQLESIVENI Q9BSP4_HUMAN Q9BSP4_HUMAN FEGLAKG--------------QVQEVGWHDVAGWLGRGGSMLGTKRTLPKGQLESIVENI B3KNQ7_HUMAN B3KNQ7_HUMAN FEGLAKG--------------QVQEVGWHDVAGWLGRGGSMLGTKRTLPKGQLESIVENI MATCH CONSENSUS F?G?AKG??????????????Q??E??W??V?GW?G?GGS?LGTKR?LP????E?I????

Q4SNL3_TETNG Q4SNL3_TETNG --------MLLPPFITS-------------------------AFMGLLELSAARDRYNEF Q4SKQ6_TETNG Q4SKQ6_TETNG RQHNINALLIIGGF--E-------------------------GFLSLLELLTARGKYEEL Q5ZHU4_CHICK Q5ZHU4_CHICK RTNNINALMVIGGF--E-------------------------AYLGLLELSAAREKYDEF Q6PF67_XENLA Q6PF67_XENLA RTNKIHALLVIGGF--E-------------------------AFLGLLEMVEGRGKYDEF A2RV78_XENLA A2RV78_XENLA RTHKINALLVIGGF--E-------------------------AYLGLLEMVEGRGKYDEF Q6P4Y8_XENTR Q6P4Y8_XENTR RTHKINALLVIGGF--E-------------------------AYLGLMEMVEGRGKYDEF K6PP_RAT K6PP_RAT HSKNINALLIIGGF--E-------------------------AYLGLLELAAARNKHEAF K6PP_MOUSE K6PP_MOUSE HSHSINALLIIGGF--E-------------------------AYLGLLELAAAREKHEAF Q8C605_MOUSE Q8C605_MOUSE HSHSINALLIIGGF--E-------------------------GYHGAIMLSEARNNHEEF K6PP_RABIT K6PP_RABIT RTHNINAILIIGGF--E-------------------------AYLGLLELSAAREKHEEF K6PP_PONAB K6PP_PONAB RTHSINALLIIGGF--E-------------------------AYLGLLELSAAREKHEEF O14943_HUMAN O14943_HUMAN RTHSINALLIIGGF--E-------------------------AYLGLLELSAAREKHEEF B3KS15_HUMAN B3KS15_HUMAN RTHSINALLIIGGF--E-------------------------AYLGLLELSAAREKHEEF Q5VSR7_HUMAN Q5VSR7_HUMAN RTHSINALLIIGGF--E-------------------------AYLGLLELSAAREKHEEF K6PP_HUMAN K6PP_HUMAN RTHSINALLIIGGF--E-------------------------AYLGLLELSAAREKHEEF Q5VSR8_HUMAN Q5VSR8_HUMAN RTHSINALLIIGGF--E-------------------------AYLGLLELSAAREKHEEF Q8WTZ9_HUMAN Q8WTZ9_HUMAN RTHSINALLIIGGF--E-------------------------AYLGLLELSAAREKHEEF K6PF_RABIT K6PF_RABIT TKFNIQGLVIIGGF--E-------------------------AYTGGLELMEGRKQFDEL K6PF_HORSE K6PF_HORSE TKFNIQGLIIVGGF--E-------------------------AYTGGLELMEGRKQYDEL K6PF_PIG K6PF_PIG TKFNIQGLVIIGGF--E-------------------------AYTGGLELMEGRKQYDEL Q1HL06_PIG Q1HL06_PIG TKFNIQGLVIIGGF--E-------------------------AYTGGLELMEGRKQYDEL K6PF_BOVIN K6PF_BOVIN TKFNIQGLVIIGGF--E-------------------------AYTGGLELMEGRKQYDEL K6PF_CANFA K6PF_CANFA TKFNIQGLIIIGGF--E-------------------------AYTGGLELMEGRKQFDEL Q1LZL7_MOUSE Q1LZL7_MOUSE ---------------------------------------------GGI------------ K6PF_RAT K6PF_RAT TKYNIQGLVIIGGF--E-------------------------AYTGGLELMEGRKQFDEL Q52KS1_RAT Q52KS1_RAT TKYNIQGLVIIGGF--E-------------------------AYTGGLELMEGRKQFDEL Q99K08_MOUSE Q99K08_MOUSE TKFNIQGLVIIGGF--E-------------------------AYTGGLELMEGRKQFDEL K6PF_MOUSE K6PF_MOUSE TKFNIQGLVIIGGF--E-------------------------AYTGGLELMEGRKQFDEL K6PF_MACFA K6PF_MACFA TKFNIQGLVIIGGF--E-------------------------AYTGGLELMEGRKQFDEL A8R0S4_MACFA A8R0S4_MACFA TKFNIQGLVIIGGF--E-------------------------AYTGGLELMEGRKQFDEL Q4R547_MACFA Q4R547_MACFA TKFNIQGLVIIGGF--E-------------------------AYTGGLELMEGRKQFDEL K6PF_PONAB K6PF_PONAB TKFNIQGLVIIGGF--E-------------------------AYTGGLELMEGRKQFDEL B4E162_HUMAN B4E162_HUMAN TKFNIQGLVIIGGF--E-------------------------AYTGGLELMEGRKQFDEL Q5RAS3_PONAB Q5RAS3_PONAB TKFNIQGLVIIGGF--E-------------------------AYTGGLELMEGRKQFDEL Q7KYX9_HUMAN Q7KYX9_HUMAN TKFNIQGLVIIGGF--E-------------------------AYTGGLELMEGRKQFDEL Q6ZTT1_HUMAN Q6ZTT1_HUMAN TKFNIQGLVIIGGF--E-------------------------AYTGGLELMEGRKQFDEL Q96I60_HUMAN Q96I60_HUMAN TKFNIQGLVIIGGF--E-------------------------AYTGGLELMEGRKQFDEL K6PF_HUMAN K6PF_HUMAN TKFNIQGLVIIGGF--E-------------------------AYTGGLELMEGRKQFDEL Q90YA3_CHICK Q90YA3_CHICK STFGIHGLIIIGGF--E-------------------------AFMGSLELMDGRAKFEEL B5DET9_XENTR B5DET9_XENTR SNYNIHGLIIIGGF--E-------------------------AFTGSLELMEGRCKYEEL Q6DD69_XENLA Q6DD69_XENLA SNYNIHGLIIVGGF--E-------------------------AFTGSLELMEGRCKYEEL Q4RVW3_TETNG Q4RVW3_TETNG SRFNIHALVIVGGF--EVSCGGGSKLPAPAELLYIVPPTCPQAYVGGLELVQAREKYEEM Q66HV8_DANRE Q66HV8_DANRE AKYNIHALVIIGGF--E-------------------------AFSGGLEMVQGREKYEEL A4QNV1_DANRE A4QNV1_DANRE AKFNIHALVIIGGF--E-------------------------AFVGGLELVTAREKYEEL Q4RXY2_TETNG Q4RXY2_TETNG AKFNIHAMVIIGGF--E-------------------------AFRGGLQMVQAREKYEEL Q4RQP4_TETNG Q4RQP4_TETNG RKFNITALLVIGGF--E-------------------------GYEGVLQLFEARTHYEEL Q59GI2_HUMAN Q59GI2_HUMAN RIYGIHALLVVGGF--E-------------------------AYEGVLQLVEARGRYEEL Q8AYP9_CHICK Q8AYP9_CHICK RKFNIQGLLVIGGF--E-------------------------AYEGVLQLVEARGQYEEL K6PL_BOVIN K6PL_BOVIN RLHNIHALLVIGGF--E-------------------------AYEGVLQLVEARGRYEEL K6PL_RAT K6PL_RAT RTYNIHALLVIGGF--E-------------------------AYEGVLQLVEARGRYEEL Q6P783_RAT Q6P783_RAT RTYNIHALLVIGGF--E-------------------------AYEGVLQLVEARGRYEEL Q8CD98_MOUSE Q8CD98_MOUSE RTYNIHALLVIGGF--E-------------------------AYEGVLQLVEARGRYEEL K6PL_MOUSE K6PL_MOUSE RTYNIHALLVIGGF--E-------------------------AYEGVLQLVEARGRYEEL Q8VDX7_MOUSE Q8VDX7_MOUSE RTYNIHALLVIGGF--E-------------------------AYEGVLQLVEARGRYEEL K6PL_PONAB K6PL_PONAB RIYGIHALLVVGGF--E-------------------------AYEGVLQLVEARGRYEEL K6PL_HUMAN K6PL_HUMAN RIYGIHALLVVGGF--E-------------------------AYEGVLQLVEARGRYEEL Q7L2M7_HUMAN Q7L2M7_HUMAN RIYGIHALLVVGGF--E-------------------------AYEGVLQLVEARGRYEEL Q9BSP4_HUMAN Q9BSP4_HUMAN RIYGIHALLVVGGF--E-------------------------AYEGVLQLVEARGRYEEL B3KNQ7_HUMAN B3KNQ7_HUMAN RIYGIHALLVVGGF--E-------------------------AYEGVLQLVEARGRYEEL MATCH . : CONSENSUS ????I??L??IGGF??E?????????????????????????AY?G?L?L???R????E?

Q4SNL3_TETNG Q4SNL3_TETNG CVPMVMVPATVSNNVPGSDLSIGSDTALNAITDRKYRFPNKLSRERLHLMVEACRPQRLL Q4SKQ6_TETNG Q4SKQ6_TETNG CVPMVMVPATVSNNVPGSDLSIGADTALNAITS--------------------------- Q5ZHU4_CHICK Q5ZHU4_CHICK CVPMVMVPATVSNNVPGSDFSIGADTALNTIT---------------------------- Q6PF67_XENLA Q6PF67_XENLA CIPMVMVPATVSNNVPGSDFSIGADTALNTIT---------------------------- A2RV78_XENLA A2RV78_XENLA CIPMVMVPATVSNNVPGSDFSIGADTALNTIT---------------------------- Q6P4Y8_XENTR Q6P4Y8_XENTR CIPMVMVPATVSNNVPGSDFSIGADTALNTIT---------------------------- K6PP_RAT K6PP_RAT CVPMVMVPATVSNNVPGSDFSIGADTALNTIT---------------------------- K6PP_MOUSE K6PP_MOUSE CVPMVMVPATVSNNVPGSDFSIGADTALNTIT---------------------------- Q8C605_MOUSE Q8C605_MOUSE CIPICVLPATISNDIPGSDISIGCDTALNVIV---------------------------- K6PP_RABIT K6PP_RABIT CVPMVMVPATVSNNVPGSDFSIGADTALNTIT---------------------------- K6PP_PONAB K6PP_PONAB CVPMVMVPATVSNNVPGSDFSIGADTALNTIT---------------------------- O14943_HUMAN O14943_HUMAN CVPMVMVPATVSNNVPGSDFSIGADTALNTIT---------------------------- B3KS15_HUMAN B3KS15_HUMAN CVPMVMVPATVSNNVPGSDFSIGADTALNTIT---------------------------- Q5VSR7_HUMAN Q5VSR7_HUMAN CVPMVMVPATVSNNVPGSDFSIGADTALNTIT---------------------------- K6PP_HUMAN K6PP_HUMAN CVPMVMVPATVSNNVPGSDFSIGADTALNTIT---------------------------- Q5VSR8_HUMAN Q5VSR8_HUMAN CVPMVMVPATVSNNVPGSDFSIGADTALNTIT---------------------------- Q8WTZ9_HUMAN Q8WTZ9_HUMAN CVPMVMVPATVSNNVPGSDFSIGADTALNTIT---------------------------- K6PF_RABIT K6PF_RABIT CIPFVVIPATVSNNVPGSDFSVGADTALNTIC---------------------------- K6PF_HORSE K6PF_HORSE CIPFVVIPATVSNNVPGSDFSVGADTALNTIC---------------------------- K6PF_PIG K6PF_PIG CIPFVVIPATVSNNVPGSDFSVGADTALNTIC---------------------------- Q1HL06_PIG Q1HL06_PIG CIPFVVIPATVSNNVPGSDFSVGADTALNTIC---------------------------- K6PF_BOVIN K6PF_BOVIN CIPFVVIPATVSNNVPGSDFSVGADTALNTIC---------------------------- K6PF_CANFA K6PF_CANFA CIPFVVIPATVSNNVPGSDFSVGADTALNTIC---------------------------- Q1LZL7_MOUSE Q1LZL7_MOUSE ------------------------------------------------------------ K6PF_RAT K6PF_RAT CIPFVVIP