Alignment of the gene Family HBG003560 of HOVERGEN

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Threshold: 50% 80% 100%
Size: Bigger Smaller Normal
Isoforms are ON
G6PC2_HUMAN G6PC2_HUMAN -------------MDFLHRNGVLIIQHLQKDYRAYYTFLNFMSNVGDPRNIFFIYFPLCF G6PC2_MOUSE G6PC2_MOUSE -------------MDFLHRSGVLIIHHLQEDYRTYYGFLNFMSNVGDPRNIFSIYFPLWF A7YY01_DANRE A7YY01_DANRE -------------MEVLYGYGISSTLYLQKHFGHAQSWFTFVSTIADLRTTFLFFFPIWF Q9IAX3_ONCMY Q9IAX3_ONCMY ------------------------------------------------------------ Q6DGA5_DANRE Q6DGA5_DANRE -------------MDLLHSWGVELAVHLQIKYQDYESVFHWVSSLADLHTTFFVFFPVWF Q4RYJ5_TETNG Q4RYJ5_TETNG -------------MDLVHSWGVELAVYLQTRHGGYQDVFSLASSLADLHTTFFFFFPIWL Q98UF8_SPAAU Q98UF8_SPAAU -------------MDLLHSWGVELAVHLQTTYSSYEGLFGLASTVADLHTTFFFFFPFWF Q8JIV3_OREMO Q8JIV3_OREMO ---------------------------------------------------------PWF G6PC_HAPNU G6PC_HAPNU -------------MDLLHSWGVELAVYLQTRYGKYEGLFDLASTVADLHTTFFWLFPIWF G6PC_HAPXE G6PC_HAPXE ------------------------------------------------------------ G6PC_MOUSE G6PC_MOUSE ---------MEEGMNILHDFGIQSTRYLQVNYQDSQDWFILVSVIADLRNAFYVLFPIWF Q91WV3_MOUSE Q91WV3_MOUSE ---------MEEGMNILHDFGIQSTRYLQVNYQDSQDWFILVSVIADLRNAFYVLFPIWF G6PC_RAT G6PC_RAT ---------MEERMNVLHDFGIQSTRYLQVNYEDSQDWFVLVSVIADLRNAFYVLFPIWF G6PC_HUMAN G6PC_HUMAN ---------MEEGMNVLHDFGIQSTHYLQVNYQDSQDWFILVSVIADLRNAFYVLFPIWF A9YUA8_PIG A9YUA8_PIG ---------MEEGMNLLHNFGIQSTRYLQVNYQDSQDWFILVSVIADLRNAFYVLFPIWF G6PC_BOVIN G6PC_BOVIN ---------MEKGMNVLHDFGIQSTHYLQVNYQNSQDWFILVSVIADLRNAFYVLFPIWF G6PC_CANFA G6PC_CANFA ---------MEKGMDVLHDFGIQSTHYLQVNYQDSQDWFILVSVIADLRNAFYVLFPIWF G6PC_FELCA G6PC_FELCA ---------MEKGMNVLHDFGIQSTHYLQVNYQDSQDWFILVSVIADLRNAFYVLFPIWF A8WH23_XENTR A8WH23_XENTR ---------METGMENLHSTGVHIVQYLQENFIKSQDWFVFVSFAADLKNTFLVLFPIWF Q6PAE1_XENLA Q6PAE1_XENLA ---------MEMGMDNLHSTGVYVVKYLQENFIKSQDWFVFVSFAADLKNTFLILFPIWF Q7ZXA0_XENLA Q7ZXA0_XENLA ---------MEMGMDNLHSTGVYIVKYLQENFIKSQDWFVFVSFAADLKNTFLILFPIWF Q7SYX6_XENLA Q7SYX6_XENLA ---------MENGMDALHDSGVQMIQYLQMNYKSSQDWFMFVSFAADLRNTFFIFFPIWF A4QNK6_XENTR A4QNK6_XENTR ---------MENGMDALHDSGVQMIQYLQMNYKSSQDWFMFVSFAADLRNTFFIFFPIWF Q642S0_XENLA Q642S0_XENLA ---------MENGMDALHDSGVQMIQYLQMNYKSSQDWFMFVSFAADLRNTFFVFFPIWF Q6DJS1_XENTR Q6DJS1_XENTR ---------MENKMDALHHSGVQMVHYLQVNYETSQDWFVFISFAADLRNTFFILFPIWF Q6PAG1_XENLA Q6PAG1_XENLA ---------MENGMDALHHSGVQIVQYLQVNYKTSQDWFVFISFAADLRNTFFILFPIWF Q9I9D2_GILMI Q9I9D2_GILMI --------MFGTVMDALQGFGVTSTHYLQTNYEDAQGLFLWVSWAADLRNTFFIFFPLWI A2VD27_DANRE A2VD27_DANRE -------------MDTMHGFGVSSTQYLQTHYKDAQGWFLFVSFAADLRNTFFIFFPIWF Q2MJT2_9TELE Q2MJT2_9TELE ---------MNAVMDTVHGFGVSSTQYLQTHYKDAQGWFLFVSFAADLRNTFFIFFPIWF B6E1X9_EPICO B6E1X9_EPICO ------------------------------------------------------------ Q4RYJ4_TETNG Q4RYJ4_TETNG --------GMNALMDAVQALGVSSTHYLQTTYPDARGLFLWVSWAADLRNTFFIFFPLWF Q4THQ4_TETNG Q4THQ4_TETNG GSLAPRLFGMNALMDAVQALGVSSTHYLQTTYPDARGLFLWVSWAADLRNTFFIFFPLWF Q0V9G2_XENTR Q0V9G2_XENTR ----------------------------------FSQFWLWVNHLGDPAHIYVIYFPLAY G6PC3_BOVIN G6PC3_BOVIN -------------MESTLGAGIAMAEALQNQLPWLENVWLWVTFLGDPKSLFLFYFPAAY G6PC3_HUMAN G6PC3_HUMAN -------------MESTLGAGIVIAEALQNQLAWLENVWLWITFLGDPKILFLFYFPAAY G6PC3_MOUSE G6PC3_MOUSE -------------MESTLSAGIIMAEALQNRLPGLENMWLWVTFLGDPKNLFQFCFPAAY G6PC3_RAT G6PC3_RAT -------------MESTLSAGIMMAEALQNQLPGLENMWLWVTFLADPKNLFQFYFPAVY G6PC3_DANRE G6PC3_DANRE -------------MESLYRQGVWMAEALQQNSRSLEDLWLVASHMGDPKAAVLLVFPVVF Q4RYG4_TETNG Q4RYG4_TETNG -------------MEAVHTQGIWFAQSLQQRTMDHQKLWLIITQLGDPKAAFLLVFPLTY MATCH CONSENSUS ?????????????M??????G??????LQ?????????????????D????F???FP???

G6PC2_HUMAN G6PC2_HUMAN QFNQTVGTKMIWVAVIGDWLNLIFKWILFGHRPYWWVQETQIYPNHSSPCLEQFPTTCET G6PC2_MOUSE G6PC2_MOUSE QLNQNVGTKMIWVAVIGDWFNLIFKWILFGHRPYWWIQETEIYPNHSSPCLEQFPTTCET A7YY01_DANRE A7YY01_DANRE HLQSAVGVKLVWVAVVGDWLNLVLKWLMFGERPYWWVRETVYYGNLTVPQIKQFPMTCET Q9IAX3_ONCMY Q9IAX3_ONCMY ------------------------------------------------------------ Q6DGA5_DANRE Q6DGA5_DANRE HLRRDVAVKLIWVAVVGDWLNLVLKWVLFGERPYWWVHETKFYGPMKHPELQQFSMTCET Q4RYJ5_TETNG Q4RYJ5_TETNG PLRRDTALRLVWVAVLGDWLNLVLKWVLFGERPYWWVQETRFYGAGPRPSLQQFPITCET Q98UF8_SPAAU Q98UF8_SPAAU HLRRDTGLRLIWVAVLGDWLNLVLKWVLFGERPYWWVHETRFYGAAPAPALRQFPITCET Q8JIV3_OREMO Q8JIV3_OREMO HLRRDTALRLIWVAVIGDWLNLVLKWVLFGERPYWWVHETKFYGAGPAPSLQQFPITCET G6PC_HAPNU G6PC_HAPNU HLRRDTALRLIWVAVIGDWLNLVLKWVLFGERPYWWVHETKFYGAGPAPSLQQFPITCET G6PC_HAPXE G6PC_HAPXE ----------------------------FGERPYWWVHETKFYGAGPAPSLQQFPITCET G6PC_MOUSE G6PC_MOUSE HLKETVGINLLWVAVVGDWFNLVFKWILFGQRPYWWVLDTDYYSNSSVPIIKQFPVTCET Q91WV3_MOUSE Q91WV3_MOUSE HLKETVGINLLWVAVVGDWFNLVFKWILFGQRPYWWVLDTDYYSNSSVPIIKQFPVTCET G6PC_RAT G6PC_RAT HIQETVGINLLWVAVVGDWFNLVFKWILFGQRPYWWVLDTDYYSNSSVPLIKQFPVTCET G6PC_HUMAN G6PC_HUMAN HLQEAVGIKLLWVAVIGDWLNLVFKWILFGQRPYWWVLDTDYYSNTSVPLIKQFPVTCET A9YUA8_PIG A9YUA8_PIG HLQEAVGIKLLWVAVIGDWLNLVFKWILFGQRPYWWVLDTDYYSNTSVPLIKQFPVTCET G6PC_BOVIN G6PC_BOVIN HLREAVGIKLLWVAVIGDWLNLVFKWILFGQRPYWWVLDTDYYSNTSAPLIKQFPVTCET G6PC_CANFA G6PC_CANFA HLREAVGIKLLWVAVIGDWLNLVFKWILFGQRPYWWVMDTDYYSNTSVPLIKQFPVTCET G6PC_FELCA G6PC_FELCA HLREAVGIKLLWVAVIGDWLNLVFKWILFGQRPYWWVMDTDYYSNASVPLIKQFPVTCET A8WH23_XENTR A8WH23_XENTR HLSESVGIKLVWVAVIGDWLNLVFKWILFGQRPYWWVHETTFFINSSAPTILQFPVTCET Q6PAE1_XENLA Q6PAE1_XENLA HISESVGVKLVWVAVIGDWLNLVFKWILFGQRPYWWVHETTFFVNNSAPTILQFPVTCET Q7ZXA0_XENLA Q7ZXA0_XENLA HLSESVGVKLVWVAVIGDWLNLVFKWILFGQRPYWWVHETTFFVNSSAPTILQFPVTCET Q7SYX6_XENLA Q7SYX6_XENLA HLHEAVGIKLIWVAVIGDWLNLVFKWILFGQRPYWWVHDTTYYGNSSAPVIEQFPVTCET A4QNK6_XENTR A4QNK6_XENTR HLCEAVGIKLIWVAVIGDWLNLVFKWILFGQRPYWWVHDTAYYGNSSAPAIEQFPVTCET Q642S0_XENLA Q642S0_XENLA HLYEAVGIKLIWVAVIGDWLNLVFKWILFGQRPYWWVHDTAYYGNSSAPVIEQFPVTCET Q6DJS1_XENTR Q6DJS1_XENTR HLCESVGIKLIWVAVIGDWLNLVFKWILFGQRPYWWVHDTDYYNNMSAPVIQQFPVTCET Q6PAG1_XENLA Q6PAG1_XENLA HLCESVGIKLIWVAVIGDWLNLVFKWILFGQRPYWWVHDTDYYNNMSAPAIQQFPVTCET Q9I9D2_GILMI Q9I9D2_GILMI HLRASVGIKLIWVAVVGDWLNLVFKWILFGERPYWWVHDASYYDNRVRPHIEQYPMTCET A2VD27_DANRE A2VD27_DANRE HLKESVGIKLIWVAVIGDWLNLVFKWILFGERPYWWVHETSYYMNSSAPHIEQYPMTCET Q2MJT2_9TELE Q2MJT2_9TELE HLKESVGIKLIWVAVIGDWLNLVFKWILFGERPYWWVHETSYYINSSAPHIEQYPMTCET B6E1X9_EPICO B6E1X9_EPICO ------------------WLNLVFKWILFGERPYWWVHETPYYANTVRPHIEQYPMTCET Q4RYJ4_TETNG Q4RYJ4_TETNG HLRPSVGIKLIWVAVIGDWLNLVFKWVLFGERPYWWVHETSYYAAAVRPHIQQYPMTCET Q4THQ4_TETNG Q4THQ4_TETNG HLRPSVGIKLIWVAVIGDWLNLVFKWVLFGERPYWWVHETSYYAAAVRPHIQQYPMTCET Q0V9G2_XENTR Q0V9G2_XENTR CICNRLGVAILWTGLLSEWLNLIFKWFLFGERPFWWIYESGMHSDL---HLTQFPLTCET G6PC3_BOVIN G6PC3_BOVIN YASRRVGIAVLWISLITEWLNLVFKWFLFGDRPFWWVHESGYYSQAPA-QVHQFPSSCET G6PC3_HUMAN G6PC3_HUMAN YASRRVGIAVLWISLITEWLNLIFKWFLFGDRPFWWVHESGYYSQAPA-QVHQFPSSCET G6PC3_MOUSE G6PC3_MOUSE YASRRLGISVLWITFIAEWLNLVFKWFLFGDRPFWWVHESGYSTQTPI-QIHQFPSSCET G6PC3_RAT G6PC3_RAT YASRRLGISLFWIAFITEWLNLVFKWFLFGDRPFWWVHESGYSAQTPV-QIHQFPSSCET G6PC3_DANRE G6PC3_DANRE YIHRRTGIAVLWVAALSEWLNLVFKWILFGERPYWWIGQSGLFSEKP-PEVQQFQSTCES Q4RYG4_TETNG Q4RYG4_TETNG FISKRTGIAVLWVAAISEWLNLVFKWMLFGERPFWWIGESHLFDNNL-PKVQQFPSTCET MATCH CONSENSUS ??????G????W?A????WLNLV?KW?LFG?RPYWWV???????????P???QFP?TCET

G6PC2_HUMAN G6PC2_HUMAN GPGS----PSGHAMGASCVWYVMVTAALSHTVCGM---DKFSITLHRLTWSFLWSVFWLI G6PC2_MOUSE G6PC2_MOUSE GPGS----PSGHAMGSSCVWYVMVTAALSYTISRM---EESSVTLHRLTWSFLWSVFWLI A7YY01_DANRE A7YY01_DANRE GPGS----PSGHAMGAAGVYYAMVTSLLLNF-------KECDPLKRWCLQALLWAVFWSV Q9IAX3_ONCMY Q9IAX3_ONCMY ---------SGHAMGSSGVWYVMITAVFSVATE-----RRFPPLLYRFLQVGLWMLLCTV Q6DGA5_DANRE Q6DGA5_DANRE GPGS----PSGHAMGSAAVGHVMITALLSILAE-----RKLPPLIYRLVQLMLWMFLGLV Q4RYJ5_TETNG Q4RYJ5_TETNG GPGS----PSGHAMGAAAIWYVMVTALLSAAR------TRCRPLLFRFLRMLLWVLMGLV Q98UF8_SPAAU Q98UF8_SPAAU GPGS----PSGHAMGAAGVWYVMVTALLATATE-----KRCPPLLYRFLQLGLWALMGLL Q8JIV3_OREMO Q8JIV3_OREMO GPGS----PSGHAMGAAGVWYVMVTALLSIARE-----KQCPPLLYRILYIGLWMLMGLV G6PC_HAPNU G6PC_HAPNU GPGS----PSGHAMGAAGVWYVMVTALLSIARE-----KQCPPLLYRFLYIGLWMLMGLV G6PC_HAPXE G6PC_HAPXE GPGS----PSGHAMGAAGVWYVMVTALLSIARE-----KQCPPLLYRFLYIGLWMLMGLV G6PC_MOUSE G6PC_MOUSE GPGS----PSGHAMGAAGVYYVMVTSTLAIFRG-----KKKPTYGFRCLNVILWLGFWAV Q91WV3_MOUSE Q91WV3_MOUSE GPGS----PSGHAMGAAGVYYVMVTSTLAIFRG-----KKKPTYGFRCLNVILWLGFWAV G6PC_RAT G6PC_RAT GPGS----PSGHAMGTAGVYYVMVTSTLAIFRG-----KKKSTYGFRCLNVVLWLGYWAV G6PC_HUMAN G6PC_HUMAN GPGS----PSGHAMGTAGVYYVMVTSTLSIFQG-----KIKPTYRFRCLNVILWLGFWAV A9YUA8_PIG A9YUA8_PIG GPGS----PSGLAMGTAGVYYVMVTSALSIIRG-----KKKPTYGFRCLNVILWLGFWTV G6PC_BOVIN G6PC_BOVIN GPGS----PSGHAMGTAGVYYVMVTSTLSIFRG-----KKKPTYRFRCLNVMLWLGFWVV G6PC_CANFA G6PC_CANFA GPGS----PSGHAMGTAGVYYVMVTSTLSIFRG-----RKRPTYRFRCLNILLWLGFWAV G6PC_FELCA G6PC_FELCA GPGS----PSGHAMGTAGVYYVMVTSTLSMFRG-----KKKPTYRFRCLNVILWLGFWAV A8WH23_XENTR A8WH23_XENTR GPGS----PSGHAMGSSSVYYVMAHAVLSILL------ENKTSLMSRFQRWALWLFFWSV Q6PAE1_XENLA Q6PAE1_XENLA GPGS----PSGHAMGSSAVYYVMAHAVLSVLL------ENKTTLRSQFQRWALWLFFWSV Q7ZXA0_XENLA Q7ZXA0_XENLA GPGS----PSGHAMGSSAVYYVMAHAVISALL------ENKTTFRSRFERCALWLFFWSV Q7SYX6_XENLA Q7SYX6_XENLA GPGS----PSGHAMGSAGIYYVMVTAIITIMLK-----KKETSLSNWCMRGALWTGFWAV A4QNK6_XENTR A4QNK6_XENTR GPGS----PSGHAMGSAGIYYVMVTAIITLMLK-----KKQTSLTNRCVCGALWAGFWAV Q642S0_XENLA Q642S0_XENLA GPGS----PSGHAMGSAGIYYVMVTAIITLMLK-----KKETSLTNWCVRGALWTGFWAV Q6DJS1_XENTR Q6DJS1_XENTR GPGS----PSGHAMGSAGIYYVIVTALVTLFLQK----KQSFSFQKKCFQALLWSGFWVI Q6PAG1_XENLA Q6PAG1_XENLA GPGS----PSGHAMGSAGIYYVVVTALITLLLKK----NKSFSFQKRCFQALLWSGFWMI Q9I9D2_GILMI Q9I9D2_GILMI GPGS----PSGHAMGAAGVYYTLVTSILALMTSRMKT-GTRNHQKKWYLXVVLWNVFCGV A2VD27_DANRE A2VD27_DANRE GPGS----PSGHAMGAAGVYYTLVTSILAIMLSK----GKKSTSNSLYLRGSLWTLFWTV Q2MJT2_9TELE Q2MJT2_9TELE GPGS----PSGHAMGAAGVYYTLVTSILAIMLSK----EKKSSSKSLYLRGSLWTLFWTV B6E1X9_EPICO B6E1X9_EPICO GPGS----PSGHAMGAAGVYYTLVTSILAIATSKKKFGSKKSTNKDWYLKAALWTLFCGV Q4RYJ4_TETNG Q4RYJ4_TETNG GPGS----PSGHAMGAAGIYYTLVTSVLALLTS-----GKSSADRRWYLKVALWTLFCGV Q4THQ4_TETNG Q4THQ4_TETNG GPGDPILKPSGHAMGAAGIYYTLVTSVLALLTS-----GKSSADRRWYLKVALWTLFCGV Q0V9G2_XENTR Q0V9G2_XENTR GPGS----PSGHCMITGAALWPVMMFFTNL--------RPQRTL----LSLVPIILYIML G6PC3_BOVIN G6PC3_BOVIN GPGS----PSGHCMITGAALWPIMTAVSS---------QMATRAHSRWVRVIPSLAYCTF G6PC3_HUMAN G6PC3_HUMAN GPGS----PSGHCMITGAALWPIMTALSS---------QVATRARSRWVRVMPSLAYCTF G6PC3_MOUSE G6PC3_MOUSE GPGS----PSGHCMITGAALWPVMTAISS---------QVASRSRSPWVRVIPGLAYCTF G6PC3_RAT G6PC3_RAT GPGS----PSGHCMITGAALWPVMIAISS---------QVASQTRSPWVRVIPGLAYCTF G6PC3_DANRE G6PC3_DANRE GPGS----PSGHAMVTSAVWWVIISSLAS---------FSQAYTGSKILSAVLYLLYAVF Q4RYG4_TETNG Q4RYG4_TETNG GPGS----PSGHAMVTAAAWWVMVSSLGSFLYV---------RTRSVALSAVPYLLYVGM MATCH ** .* :. : . CONSENSUS GPGS????PSGHAMG?????????T???????????????????????????LW??????

G6PC2_HUMAN G6PC2_HUMAN QISVCISRVFIATHFPHQVILGVIG----------------------GMLVAEAFEHTP- G6PC2_MOUSE G6PC2_MOUSE QISVCISRVFIATHFPHQVILGVIG----------------------GMLVAEAFEHTP- A7YY01_DANRE A7YY01_DANRE QVCVSLSRVFIAAHFPHRVIAGVFS----------------------GIAVAKAFNRVS- Q9IAX3_ONCMY Q9IAX3_ONCMY ELLVCMSRVYMAAHFPHQVISGVIT----------------------GIMVAEAFSRVQ- Q6DGA5_DANRE Q6DGA5_DANRE ELLVCMSRVYLAAHFPHQVICGVIS----------------------GIIVAETFSRVQ- Q4RYJ5_TETNG Q4RYJ5_TETNG LLLVCTSRVFMAAHFPHQVIAGMVS----------------------GVLVAEVVSRQK- Q98UF8_SPAAU Q98UF8_SPAAU VLVVCMSRVYMAAHFPHQVIAGVIT----------------------GVLVAEVVSKEK- Q8JIV3_OREMO Q8JIV3_OREMO ELVVCMSRVYMAAHFPHQVIAGIIT----------------------GTLVAEVVSKEK- G6PC_HAPNU G6PC_HAPNU ELVVCISRVYMAAHFPHQVIAGIIT----------------------GTLVAEVVSKEK- G6PC_HAPXE G6PC_HAPXE ELVVCISRVYMAAHFPHQVIAGIIT----------------------GTLVAEVVSKEK- G6PC_MOUSE G6PC_MOUSE QLNVCLSRIYLAAHFPHQVVAGVLS----------------------GIAVAETFSHIR- Q91WV3_MOUSE Q91WV3_MOUSE QLNVCLSRIYLAAHFPHQVVAGVLS----------------------GIAVAETFSHIR- G6PC_RAT G6PC_RAT QLNVCLSRIYLAAHFPHQVVAGVLS----------------------GIAVAETFSHIR- G6PC_HUMAN G6PC_HUMAN QLNVCLSRIYLAAHFPHQVVAGVLS----------------------GIAVAETFSHIH- A9YUA8_PIG A9YUA8_PIG QLNVCLSRIYLAAHFPHQVVAGVLS----------------------GIAVAETFRHIQ- G6PC_BOVIN G6PC_BOVIN QLNVCLSRIYLAAHFPHQVVAGVLS----------------------GIAVAETFRHIQ- G6PC_CANFA G6PC_CANFA QLNVCLSRIYLAAHFPHQVVAGVLS----------------------GIAVAETFRHIQ- G6PC_FELCA G6PC_FELCA QLNVCLSRIYLAAHFPHQVVAGVLS----------------------GIAVAETFRHIQ- A8WH23_XENTR A8WH23_XENTR QVNVCLSRVFVAAHFPHQVIAGVFS----------------------GMLVAEMFNHIQ- Q6PAE1_XENLA Q6PAE1_XENLA QVNVCLSRVFVAAHFPHQVIAGVCS----------------------GMLVAKIFNHVH- Q7ZXA0_XENLA Q7ZXA0_XENLA QVNVCLSRVFVAAHFPHQVIAGVFS----------------------GMLVAEIFNHVQ- Q7SYX6_XENLA Q7SYX6_XENLA QVCVCLSRIFLAAHFPHQVVAGVIS----------------------GMVVAEAFHHTQ- A4QNK6_XENTR A4QNK6_XENTR QVCVCLSRIFLAAHFPHQVVAGVIS----------------------GIVVAEAFHHTQ- Q642S0_XENLA Q642S0_XENLA QVCVCLSRIFLAAHFPHQVVAGVIS----------------------GMVVAEAFHHTQ- Q6DJS1_XENTR Q6DJS1_XENTR QACVCLSRVFLAAHFPHQVICGVIA----------------------GMVVAEVFEHIQ- Q6PAG1_XENLA Q6PAG1_XENLA QACVCLSRVFLAAHFPHQVICGVIA----------------------GMVVAEVFEHIQ- Q9I9D2_GILMI Q9I9D2_GILMI QCAVSVKVS------PPTFSSGLL------------------------------------ A2VD27_DANRE A2VD27_DANRE QICVCLSRVFIAAHFPHQVFAGVIS----------------------GMIVAEAFNRQK- Q2MJT2_9TELE Q2MJT2_9TELE QVCVCLSRVFIAAHFPHQVFAGVIS----------------------GMIVAEAFNRQK- B6E1X9_EPICO B6E1X9_EPICO QVCVCLSRVFIAAHFPHQVVAGVIS----------------------GMIVAEAFNRTQ- Q4RYJ4_TETNG Q4RYJ4_TETNG QVCVCLSRVFIAAHFPHQVVAGVISGQRRSARPACRPSSAVDPALSAGMLVAEAFNRTR- Q4THQ4_TETNG Q4THQ4_TETNG QVCVCLSRVFIAAHFPHQVVAGVI------------------------------------ Q0V9G2_XENTR Q0V9G2_XENTR MVGVAISRVLILAHFPHQVVAGLIA----------------------GMYLGHSIPGT-- G6PC3_BOVIN G6PC3_BOVIN LLAVGLSRVFLLAHFPHQVLAGLIT----------------------GA-VLGWLMTPQ- G6PC3_HUMAN G6PC3_HUMAN LLAVGLSRIFILAHFPHQVLAGLIT----------------------GA-VLGWLMTPR- G6PC3_MOUSE G6PC3_MOUSE LLAVGLSRVFLLAHFPHQVLGGLIV----------------------GAAL-GWLMSPR- G6PC3_RAT G6PC3_RAT LLAVGLSRVFLLAHFPHQVLAGLLA----------------------GV-ILGWLLSPR- G6PC3_DANRE G6PC3_DANRE LGCVGLSRIFILAHFPHQVVAGLLT----------------------GV-LLGVFLKRS- Q4RYG4_TETNG Q4RYG4_TETNG LVAVGLSRIFILAHFPHQVIAGSVS----------------------GLSFVTLRQHIHI MATCH * . * . * CONSENSUS ???V??SR????AHFPHQV??G?????????????????????????G??V?????????

G6PC2_HUMAN G6PC2_HUMAN -------GIQTASL-----------------GTYLKTNLFLFLFAVGFYLLLRVLNIDLL G6PC2_MOUSE G6PC2_MOUSE -------GVHMASL-----------------SVYLKTNVFLFLFALGFYLLLRLFGIDLL A7YY01_DANRE A7YY01_DANRE -------WIYSASL-----------------KGYMHSILCLVFVALGLYAVLDAASIDPY Q9IAX3_ONCMY Q9IAX3_ONCMY -------WIYGASL-----------------KKYFYTTLFLLSFAVGFYELLKAIGVDLL Q6DGA5_DANRE Q6DGA5_DANRE -------WIYSASL-----------------KKYFSITLFLLSFAVGFYVLLKALGVDLL Q4RYJ5_TETNG Q4RYJ5_TETNG -------WIYGASL-----------------RSYICTTLLLTSFAVGFYLLLRAVGVDLL Q98UF8_SPAAU Q98UF8_SPAAU -------WIYDASM-----------------RKYFHTTLSLTSLAVGFYLLLRVLGVDLL Q8JIV3_OREMO Q8JIV3_OREMO -------WIYSASL-----------------KKYFLITLFLTSFAVGFYVLLKALDVDLL G6PC_HAPNU G6PC_HAPNU -------WIYSASL-----------------KKYFLITLFLTSFAVGFYVLLKALDVDLL G6PC_HAPXE G6PC_HAPXE -------WIYSASL-----------------KKYFLITLFLTSFAVGFYVLLKALDVDLL G6PC_MOUSE G6PC_MOUSE -------GIYNASL-----------------RKYCLITIFLFGFALGFYLLLKGLGVDLL Q91WV3_MOUSE Q91WV3_MOUSE -------GIYNASL-----------------RKYCLITIFLFGFALGFYLLLKGLGVDLL G6PC_RAT G6PC_RAT -------GIYNASL-----------------QRYCLITFFLFGFALGFYLLLKGLGVDLL G6PC_HUMAN G6PC_HUMAN -------SIYNASL-----------------KKYFLITFFLFSFAIGFYLLLKGLGVDLL A9YUA8_PIG A9YUA8_PIG -------SIYNASL-----------------KKYFLITFFLFSFAIGFYLLLKGLGVDLS G6PC_BOVIN G6PC_BOVIN -------SIYNASL-----------------KKYFLITCFLFSFAIGFYLLLKWLGVDLL G6PC_CANFA G6PC_CANFA -------SIYNASL-----------------KKYFLITFFLFSFAIGFYLLLKGLGVDLL G6PC_FELCA G6PC_FELCA -------SIYNASL-----------------KKYFFITFFLLSFAIGFYLLLKGLGVDLL A8WH23_XENTR A8WH23_XENTR -------CIYNASF-----------------KRYLHATLFLFFFALGFFLLLKVFGVDLL Q6PAE1_XENLA Q6PAE1_XENLA -------CIYNVSF-----------------KRYIYATLFLFFFALGFYLILKVFGIDLL Q7ZXA0_XENLA Q7ZXA0_XENLA -------CIYKTSF-----------------KRYIYATLFLFFFALGFFLLLKVFGVDLL Q7SYX6_XENLA Q7SYX6_XENLA -------LIYKANL-----------------KKYIYTTLFLFSFALGFYLLLKSVGVDLL A4QNK6_XENTR A4QNK6_XENTR -------LIYKASL-----------------KKYIYTTLFLFSFALGFYLLLKAVGVDLL Q642S0_XENLA Q642S0_XENLA -------LIYKASL-----------------KKYIYTTLFLFSFALGFYLLLKAVGVDLL Q6DJS1_XENTR Q6DJS1_XENTR -------SIYKASL-----------------NKYIYTTLFLFCFALGFYLVLKTVGVDLL Q6PAG1_XENLA Q6PAG1_XENLA -------SIYKANL-----------------NKYIYTTLFLFCFALGFYLVLKIVGVDLL Q9I9D2_GILMI Q9I9D2_GILMI ----------------------------------------------GLTGIMS------- A2VD27_DANRE A2VD27_DANRE -------WIYSASL-----------------KNYFNVTLFLLSFAVGLYVLLKALGVDLL Q2MJT2_9TELE Q2MJT2_9TELE -------WIYSASL-----------------KNYFNVTLFLLSFAVGLYVLLKALGVDLL B6E1X9_EPICO B6E1X9_EPICO -------WIYNASM-----------------KKYFYTTLFLTSFAVGFYVLLKAVGVDLL Q4RYJ4_TETNG Q4RYJ4_TETNG -------WIYGASL-----------------RSYVCTTLLLTSFAVGFYLLLRAVGVDLL Q4THQ4_TETNG Q4THQ4_TETNG ------------------------------------------------------------ Q0V9G2_XENTR Q0V9G2_XENTR -------VSRGCTL-----------------LFFTLTSVLLLFGAFLIYFGMGIFGVDLS G6PC3_BOVIN G6PC3_BOVIN -------VPMEREL-----------------SFYGLTSLALLLGASLIYWTLFTLGLDLS G6PC3_HUMAN G6PC3_HUMAN -------VPMEREL-----------------SFYGLTALALMLGTSLIYWTLFTLGLDLS G6PC3_MOUSE G6PC3_MOUSE -------VPMEREL-----------------SFYGLTALALMLGASLMYWTLFTLGLDLS G6PC3_RAT G6PC3_RAT -------VPMEREL-----------------SFYGLTALTLMLGASLMYWTLFTLGLDLS G6PC3_DANRE G6PC3_DANRE -------VPERRPL-----------------LFFFRFSMALLGAALIFHAVLEKTGIDLS Q4RYG4_TETNG Q4RYG4_TETNG YQSLILGWKFKILIALGFILGIILSGRVPQGRSLLFISIALLLGTVGLYTGLQWLGLKLS MATCH CONSENSUS ?????????????????????????????????Y??????L???A?G?Y??L???G?DL?

G6PC2_HUMAN G6PC2_HUMAN WSVPIAKKWCANPDWIHIDTTPFAGLVRNLGVLFGLGFAINSEMFLLSCRGGNNYTLS-- G6PC2_MOUSE G6PC2_MOUSE WSVPIAKKWCANPDWIHIDSTPFAGLVRNLGVLFGLGFAINSEMFLRSCQGENGTKPS-- A7YY01_DANRE A7YY01_DANRE WSLMKAQKWCIQSEWVHLDTTPFAGLLRNTGALFGLGLSLHLPTHGDLQKKKKK------ Q9IAX3_ONCMY Q9IAX3_ONCMY WSLEKAQKWCVRAEWVYMDSTPFAILLRNMGTLFGLGLGLHSPLYTEN----KNSSIP-- Q6DGA5_DANRE Q6DGA5_DANRE WTLEKAQKWCINPAWVLMDATPFASLLRNMGTLFGLGLGLHLSHYDPGSSKKHTCIC--- Q4RYJ5_TETNG Q4RYJ5_TETNG WTMEKAQRWCARPEWVHLDTTPFASLLRNMGSLLGLGLGLHSPPSRSSSKPGSAS----- Q98UF8_SPAAU Q98UF8_SPAAU WTMEKAQKWCVNPEWVHLDSTPFASLLRNMGTLFGLGLGLHSPLNSETKNTSTS------ Q8JIV3_OREMO Q8JIV3_OREMO WTMEKAQKW--------------------------------------------------- G6PC_HAPNU G6PC_HAPNU WTMEKAQKWCIRPEWVHLDSAPFASLLRNMGSLFGLGLGLHSPFYKTTKMRIMSAPL--- G6PC_HAPXE G6PC_HAPXE WTMEKAQKWCIRPEWVHLDSAPFASLLRNMGSLFGLGLGLHSPFYKTTKMRIMSAPL--- G6PC_MOUSE G6PC_MOUSE WTLEKAKRWCERPEWVHLDTTPFASLFKNLGTLLGLGLALNSSMYRKSCKGELSKSFP-- Q91WV3_MOUSE Q91WV3_MOUSE WTLEKAKRWCERPEWVHLDTTPFASLFKNLGTLLGLGLALNSSMYRKSCKGELSKLLP-- G6PC_RAT G6PC_RAT WTLEKAKRWCERPEWVHLDTTPFASLFKNLGTLLGLGLALNSSMYRKSCKGELRKSLP-- G6PC_HUMAN G6PC_HUMAN WTLEKAQRWCEQPEWVHIDTTPFASLLKNLGTLFGLGLALNSSMYRESCKGKLSKWLP-- A9YUA8_PIG A9YUA8_PIG WTLEKAKRRCERPEWVHIDTTPFASLLKNVGTLFGLGLALNSSMYRQGCKGKLSKWFP-- G6PC_BOVIN G6PC_BOVIN WTLEKAKRRCERPEWVHIDTTPFASLLKNLGTLFGLGLALNSSMYRESCKGKLSKWFP-- G6PC_CANFA G6PC_CANFA WTLEKARRWCERPEWVHIDTTPFASLLKNVGTLFGLGVTLNSSMYRESCKGKLSKWFP-- G6PC_FELCA G6PC_FELCA WTLEKARRWCERPEWVHIDTTPFASLLKNVGTLFGLGLALNSSMYRESCKGTLSKWFP-- A8WH23_XENTR A8WH23_XENTR WTLEKAKRWCARPEWIHIDTTPFAGLLRNLGVFFGLGLALDTQMYRDSCRGKKSGQFT-- Q6PAE1_XENLA Q6PAE1_XENLA WALEKAKRWCARPEWIHIDTTPFAGLLRNLGVFFGLGLALDTQMYRDSCREKKGGQFT-- Q7ZXA0_XENLA Q7ZXA0_XENLA WTLEKAKRWCARPEWIHIDTTPFAGLLRNLGVFFGLGLALNTQMYRDSCRRKKGAQFT-- Q7SYX6_XENLA Q7SYX6_XENLA WTLEKAKRWCAQPEWIHINTTPFAGLLRNLGIFFGLGLALNSKLYQESCRGKKGSQFT-- A4QNK6_XENTR A4QNK6_XENTR WTLEKAKRWCARPEWIHIDTTPFAGLLRNLGIFLGLGLALNSKLYQESCRGKKGSQFT-- Q642S0_XENLA Q642S0_XENLA WTLEKAKRWCAQPEWIHIDTTPFAGLLRNLGIFFGLGLALNSKLYQESCGGKKGSQFT-- Q6DJS1_XENTR Q6DJS1_XENTR WTIEKAKRWCSQPEWIHIDTTPFAGLLRNLGIFFGLGLALNSPMYKDYCQGKQGRHFG-- Q6PAG1_XENLA Q6PAG1_XENLA WTLQKAKRWCSQPEWIHIDTTPFAGLLRNLGIFFGLGLALNSQMYKDSCQGKHSRRFS-- Q9I9D2_GILMI Q9I9D2_GILMI ------------------------------------------------------------ A2VD27_DANRE A2VD27_DANRE WTLEKAQKWCANPAWVHLDTTPFASLLRNMGTLFGLGLGLHSPLYTESKKSSNAFV---- Q2MJT2_9TELE Q2MJT2_9TELE WTLEKAQRWCVNPAWVHLDTTPFASLLRNMGTLFGLGLGLHSPLYTESKKSSNARV---- B6E1X9_EPICO B6E1X9_EPICO WTLEKAQRWCDRPEWVHLDSTPF------------------------------------- Q4RYJ4_TETNG Q4RYJ4_TETNG WTMEKAQRWCARPEWVHLDTTPFASLLRNMGTLFGLGLGLHSPLYTQSKQSSSGRA---- Q4THQ4_TETNG Q4THQ4_TETNG ------------------------------------------------------------ Q0V9G2_XENTR Q0V9G2_XENTR WSINRATKWCAKPEWVRLETRPFSSVTRSAASALGLGFAFRCPLYSRLCKGNRDWRK--- G6PC3_BOVIN G6PC3_BOVIN WSINLASKWCERPEWVHLDSRPFASLSRDSGAALGLGIALHSPCYAQVRRAHLGYGQ--- G6PC3_HUMAN G6PC3_HUMAN WSISLAFKWCERPEWIHVDSRPFASLSRDSGAALGLGIALHSPCYAQVRRAQLGNGQ--- G6PC3_MOUSE G6PC3_MOUSE WSINLASKWCERPEWVHMDSRPFASLSRDSGSALGLGIALHTPCYAQIRRAHLGNGQ--- G6PC3_RAT G6PC3_RAT WSINLASKWCDRPEWVLVDSRPFASLSRDSGSALGLGIALHTPCYAQIRRVHLGNGQ--- G6PC3_DANRE G6PC3_DANRE WSISLAKRWCSRSEWVRMDTAPFSSLNRDAGVLLGLGLA--------QYWKPGGWTLPRA Q4RYG4_TETNG Q4RYG4_TETNG WSILLAKKWCSRPDWIRMETAPFSALIRDCGTLLGLGLA--------QCWRPCGWPLPRA MATCH CONSENSUS W????A??WC??P?W???D??PFA?L????G???GLG???????????????????????

G6PC2_HUMAN G6PC2_HUMAN FRLLCALTSLTILQLYHFLQIPTHEEHLFYVLSFCKSASIPLTVVAFIPYSVHMLMKQSG G6PC2_MOUSE G6PC2_MOUSE FRLLCALTSLTTMQLYRFIKIPTHAEPLFYLLSFCKSASIPLMVVALIPYCVHMLMRPGD A7YY01_DANRE A7YY01_DANRE ------------------------------------------------------------ Q9IAX3_ONCMY Q9IAX3_ONCMY FRVGCITVSLLLLQILDGLTFSSRDQAMFYTLSFG------------------------- Q6DGA5_DANRE Q6DGA5_DANRE FRIGCIGVSLVLLQLLDKMTFSSSSQ-LFYLLSFCKSAVALLLPTALVPGIMYWITQKKQ Q4RYJ5_TETNG Q4RYJ5_TETNG -RTGRIAASLLLLQLWDMWTFSSENLLIFYFLSFAKSMVALLIPTRLVPWAL-------- Q98UF8_SPAAU Q98UF8_SPAAU FKTGCIIVSLFLLHLLDGWTFSSENLTTFYFLSFGKSAVALLIPTTLVPFALCWIRPGKT Q8JIV3_OREMO Q8JIV3_OREMO ------------------------------------------------------------ G6PC_HAPNU G6PC_HAPNU -RIGCIVISVSLLHLLDGWTFSPENHMTFYALSFGKSAVALLIPTTLVPWALSKIYPVKT G6PC_HAPXE G6PC_HAPXE -RIGCIVISVSLLHLLDGWTFSPENHMTFYALSFGKSAVALLIPTTLVPWALSKIYPVKT G6PC_MOUSE G6PC_MOUSE FRFACIVASLVLLHLFDSLKPPSQVELIFYILSFCKSATVPFASVSLIPYCLARILGQTH Q91WV3_MOUSE Q91WV3_MOUSE FRFACIVASLVLLHLFDSLKPPSQVELIFYILSFCKSATVPFASVSLIPYCLARILGQTH G6PC_RAT G6PC_RAT FRLACIVASLGLLHLFDSLKPPSQIESIFYILSFCKSATVPFASVSLIPYCLARLLGQTH G6PC_HUMAN G6PC_HUMAN FRLSSIVASLVLLHVFDSLKPPSQVELVFYVLSFCKSAVVPLASVSVIPYCLAQVLGQPH A9YUA8_PIG A9YUA8_PIG FRLSCIVASLVLLHFFDSLKPPSQIELIFYVLSFCKSAAVPLASVSLIPYCLSRALGQPD G6PC_BOVIN G6PC_BOVIN FRLSCIVASLVLLHLFDSLKPPSQIELIFYVLSFCKSAAVPLASVSLIPYCLAWVLGQPN G6PC_CANFA G6PC_CANFA FRLSCIVVSLILLHLFDSLKPPSQTELIFYTLSFCKSAAVPLASVSLIPYCLARVFDQPD G6PC_FELCA G6PC_FELCA FRLSCIVVSLILLHLFDSLKPPSQIELIFYVLSFCKSAAVPLASVSLIPYCLARVLGQPD A8WH23_XENTR A8WH23_XENTR FRLCCIMISLLVLHLFDSLELPADKEILFYFLSFCRSVAVSLAVVAVIPYCISHALQWQK Q6PAE1_XENLA Q6PAE1_XENLA FRLCCIMISLLVLHLFDSLELPADKEILFYFLSFCRSVAVSLTVVAVIPFCISHALQWQK Q7ZXA0_XENLA Q7ZXA0_XENLA FRLCCIMISLLVLHLFDSLELPADNEILFYFLSFCRSVTVSLAVVAVVPYCISHALQWQK Q7SYX6_XENLA Q7SYX6_XENLA FRLCCIVASLLVLHLFDSFKPPTQVEMLFYALSFCKSAAVPLAAVGIIPYCVSQVLHQQN A4QNK6_XENTR A4QNK6_XENTR FRLCCIVASLLVLHLFDSFKPPTKVEMLFYALSFCKSAAVPLAAVGIIPYCVSQVLHQQN Q642S0_XENLA Q642S0_XENLA FRLCCIVASLLVLHLFDSFKPPTKVEMLFYALSFCKSAAVPLAAVGIIPYCVSQVLHKQN Q6DJS1_XENTR Q6DJS1_XENTR FRLCCIIASLLVLHLFDSFKPPTKVEMIFYALSFCKSAAVPLTCVAIIPYCVSQIVNRKE Q6PAG1_XENLA Q6PAG1_XENLA YRLGCIIASLLVLHLFDSFKPPTKVEMLFYSLSFCKSAAVPLTCVAIIPYCISQIVNRKE Q9I9D2_GILMI Q9I9D2_GILMI ------------------------------------------------------------ A2VD27_DANRE A2VD27_DANRE -RITCIIASLLLLHLFDSIKPPTHTAALFYLLSFCKSATVPLVTVSIIPYCLSGALGLQS Q2MJT2_9TELE Q2MJT2_9TELE -RIACIVASLFLLHLFDSIKPPTHTAALFYLLSFCKSATVPLATVSIIPYCVSGTLGLQS B6E1X9_EPICO B6E1X9_EPICO ------------------------------------------------------------ Q4RYJ4_TETNG Q4RYJ4_TETNG -RAACAVASLVLLHLFDSVKPPTHTAALFYLLSFCKSATVPLVTISIIPYCVSAALS--- Q4THQ4_TETNG Q4THQ4_TETNG ------------------------------------------------------------ Q0V9G2_XENTR Q0V9G2_XENTR -RTITLLLSLLLLGLLHHLPLQTASPLLFYFLNFIRHVLGPFAVVILAPFITHSLSMRAT G6PC3_BOVIN G6PC3_BOVIN -KLVCLVLAMGLLGPLNWLGYPPQIS-LFYIFNFLKYTLWPCLVLALVPWLVHMFSAQEA G6PC3_HUMAN G6PC3_HUMAN -KIACLVLAMGLLGPLDWLGHPPQIS-LFYIFNFLKYTLWPCLVLALVPWAVHMFSAQEA G6PC3_MOUSE G6PC3_MOUSE -KIACFVLAMGLLVFLEWLGYPPQIS-LFYIFNFLKYTLWPCLVLALVPWVVHTLSDQEA G6PC3_RAT G6PC3_RAT -KIACFVLAMGLLVFLEWLGHPPQIS-LFYIFNFLKFTLWPCLVVALVPWMVHTLSAQEA G6PC3_DANRE G6PC3_DANRE PRTLCLALSSLALHYISRFPLPTVPPLLFYSLFFLKYSIVPQVVMVLVPGFVHLLTAKPK Q4RYG4_TETNG Q4RYG4_TETNG SRALSLAVSSMGLYHINRLPLPPQPLGLFYGCFLLKHFLVPQLVMMLVPGLIYLFT---- MATCH CONSENSUS ????????????L???????????????FY???F??????????????P???????????

G6PC2_HUMAN G6PC2_HUMAN KKSQ-- G6PC2_MOUSE G6PC2_MOUSE KKTK-- A7YY01_DANRE A7YY01_DANRE ------ Q9IAX3_ONCMY Q9IAX3_ONCMY ------ Q6DGA5_DANRE Q6DGA5_DANRE A----- Q4RYJ5_TETNG Q4RYJ5_TETNG ------ Q98UF8_SPAAU Q98UF8_SPAAU EDKNL- Q8JIV3_OREMO Q8JIV3_OREMO ------ G6PC_HAPNU G6PC_HAPNU EGKNL- G6PC_HAPXE G6PC_HAPXE EGKNL- G6PC_MOUSE G6PC_MOUSE KKSL-- Q91WV3_MOUSE Q91WV3_MOUSE KKSL-- G6PC_RAT G6PC_RAT KKSL-- G6PC_HUMAN G6PC_HUMAN KKSL-- A9YUA8_PIG A9YUA8_PIG KKTL-- G6PC_BOVIN G6PC_BOVIN KKTV-- G6PC_CANFA G6PC_CANFA KKSL-- G6PC_FELCA G6PC_FELCA KKSL-- A8WH23_XENTR A8WH23_XENTR KKVT-- Q6PAE1_XENLA Q6PAE1_XENLA KKVT-- Q7ZXA0_XENLA Q7ZXA0_XENLA KKFT-- Q7SYX6_XENLA Q7SYX6_XENLA KKSL-- A4QNK6_XENTR A4QNK6_XENTR KKSL-- Q642S0_XENLA Q642S0_XENLA KKSL-- Q6DJS1_XENTR Q6DJS1_XENTR KVL--- Q6PAG1_XENLA Q6PAG1_XENLA KVL--- Q9I9D2_GILMI Q9I9D2_GILMI ------ A2VD27_DANRE A2VD27_DANRE KKQL-- Q2MJT2_9TELE Q2MJT2_9TELE KKQL-- B6E1X9_EPICO B6E1X9_EPICO ------ Q4RYJ4_TETNG Q4RYJ4_TETNG ------ Q4THQ4_TETNG Q4THQ4_TETNG ------ Q0V9G2_XENTR Q0V9G2_XENTR DKKE-- G6PC3_BOVIN G6PC3_BOVIN PPIRSS G6PC3_HUMAN G6PC3_HUMAN PPIHSS G6PC3_MOUSE G6PC3_MOUSE PPIRSS G6PC3_RAT G6PC3_RAT PPIRSS G6PC3_DANRE G6PC3_DANRE RE---- Q4RYG4_TETNG Q4RYG4_TETNG ------ MATCH CONSENSUS ??????


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