Alignment of the gene Family HBG003941 of HOVERGEN

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Isoforms are ON
Q4T062_TETNG Q4T062_TETNG ----------------------------MLMYDYPLKTDMETSFYSSLVKSPEPYGVIFS A2BG67_DANRE A2BG67_DANRE ----------------------------MLTCD-PKPDMSLYQPYSTLIKSHETFGMVLP Q90XE9_DANRE Q90XE9_DANRE ----------------------------MLTCD-PKPDMSLYQPYSTLIKSHETFGMVLP Q6NYD5_DANRE Q6NYD5_DANRE ----------------------------MLTCD-PKPDMSLYQPYSTLIKSHETFGMVLP B4YSE3_PIG B4YSE3_PIG ----------------------------MLMFD-PVPVK---QEAMDPVSVSYPSSYMES KLF3_MOUSE KLF3_MOUSE ----------------------------MLMFD-PVPVK---QEAMDPVSVSFPSNYIES Q545J5_MOUSE Q545J5_MOUSE ----------------------------MLMFD-PVPVK---QEAMDPVSVSFPSNYIES Q8BV07_MOUSE Q8BV07_MOUSE ------------------------------------------------------------ A1YES7_9PRIM A1YES7_9PRIM ---------------------------------------------------SYPSNYMES B2R8P9_HUMAN B2R8P9_HUMAN ----------------------------MLMFD-PVPVK---QEAMDPVSVSYPSNYMES A1YFZ4_PANPA A1YFZ4_PANPA ---------------------------------------------------SYPSNYMES KLF3_HUMAN KLF3_HUMAN ----------------------------MLMFD-PVPVK---QEAMDPVSVSYPSNYMES B8JID2_DANRE B8JID2_DANRE ----------------------------MLMLD-GMPTL---PVKINPAESQRRSPVIHD Q6NYX3_DANRE Q6NYX3_DANRE ----------------------------MLMLD-GMPTL---PVKINPAESQRRSPVIHD KLF12_MOUSE KLF12_MOUSE ---------MNIHMKRKTIKNLSALENRMLMLD-GMPAV---RVKTELVESEQGSPNVHN Q6NWV9_MOUSE Q6NWV9_MOUSE ---------MNIHMKRKTIKNLSALENRMLMLD-GMPAV---RVKTELVESEQGSPNVHN B4YSE9_PIG B4YSE9_PIG ---------MNIHMKRKTIKNIDTFENRMLMLD-GMPAV---RVKTELLESEQGSPNVHN KLF12_HUMAN KLF12_HUMAN ---------MNIHMKRKTIKNINTFENRMLMLD-GMPAV---RVKTELLESEQGSPNVHN Q8WWI3_HUMAN Q8WWI3_HUMAN ---------MNIHMNRKTIKNINTFENRMLMLD-GMPAV---RVKTELLESEQGSPNVHN Q4RWC7_TETNG Q4RWC7_TETNG -----------------------SLRNRMLMLD-GMPAV---RVKAEPLESEQGSPKVRP A7MBV2_DANRE A7MBV2_DANRE -----------------------------------MPAV---RVKAEPLESERGSPKVHG B8JL63_DANRE B8JL63_DANRE ----------------------------MLMLD-GMPAV---RVKAEPLESERGSPKVHG A6PWN2_MOUSE A6PWN2_MOUSE ------MDKFIDNMDVRIKSESGSMQVFKQVTG-PVPTR---DPSARADRRNMTSPSFLA KLF8_MOUSE KLF8_MOUSE ------MDKFIDNMDVRIKSESGSMQVFKQVTG-PVPTR---DPSARADRRNMTSPSFLA B4YSE6_PIG B4YSE6_PIG ---MGDMDQLINNLEVQLNSETGSMHVFKQVTG-SVQIR---DSLKTTGRGDMTSPPLLD Q05BZ3_HUMAN Q05BZ3_HUMAN ---MVDMDKLINNLEVQLNSEGGSMQVFKQVTA-SVRNR---DPPEIEYRSNMTSPTLLD B4DJN3_HUMAN B4DJN3_HUMAN ---MVDMDKLINNLEVQLNSEGGSMQVFKQVTA-SVRNR---DPPEIEYRSNMTSPTLLD KLF8_HUMAN KLF8_HUMAN ---MVDMDKLINNLEVQLNSEGGSMQVFKQVTA-SVRNR---DPPEIEYRSNMTSPTLLD B1H3D6_XENTR B1H3D6_XENTR -----------------------------------------------------------M B7ZR90_XENLA B7ZR90_XENLA ----------------------MQMPFIARVCN----------------SSPLISGCKM- Q7T3J7_XENLA Q7T3J7_XENLA ----------------------MQMPFIARVCN----------------SSPLTSGCKM- A0S0R1_DANRE A0S0R1_DANRE -----------MHTETRNKKCQTSPKKSAAATSEPVEEM----PSIQIKPEPEEVECMVK B0R0G2_DANRE B0R0G2_DANRE SLVRLINSFSLSRSNLGEFMCQTSPKKSAAATSEPVEEM----PSIQIKPEPEEVECMVK Q4T2S4_TETNG Q4T2S4_TETNG -------------------------------------------------------PAAQP MATCH CONSENSUS ????????????????????????????????????????????????????????????

Q4T062_TETNG Q4T062_TETNG HPAHLYHPTHMQ---AFAPTPG--------SLTHTQQEPVDLSVSKRSSSSSNSSSSSPP A2BG67_DANRE A2BG67_DANRE PAVVSGAHLYPSHYHPSYQLPY--SHRQSQDVHQAQIEPVDLSIGNKSSGSSPSSSLASS Q90XE9_DANRE Q90XE9_DANRE PAVVSGAHLYPSHYHPSYQLPY--SHRQSQDVHQAQIEPVDLSIGNKSSGSSPSSSLASS Q6NYD5_DANRE Q6NYD5_DANRE PAVVSGAHLYPSHYHPSYQLPY--SHRQSQDVHQAQIEPVDLSIGNKSSGSSPSSSLASS B4YSE3_PIG B4YSE3_PIG IKPNKYGVIYST------PLPDKFFQTPEGLSHGMQMEPVDLTVNK-RSSPPSAGGSPSS KLF3_MOUSE KLF3_MOUSE MKPNKYGVIYST------PLPDKFFQTPEGLTHGIQVEPVDLTVNK-RGSPPAAGGSPSS Q545J5_MOUSE Q545J5_MOUSE MKPNKYGVIYST------PLPDKFFQTPEGLTHGIQVEPVDLTVNK-RGSPPAAGGSPSS Q8BV07_MOUSE Q8BV07_MOUSE -------------------------------------------------SPPAAGGSPSS A1YES7_9PRIM A1YES7_9PRIM MKPNKYGVIYST------PLPEKFFQTPEXXSHGIQMEPVDLTVNK-RSSPPSAGNSPSS B2R8P9_HUMAN B2R8P9_HUMAN MKPNKYGVIYST------PLPEKFFQTPEGLSHGIQMEPVDLTVNK-RSSPPSAGNSPSS A1YFZ4_PANPA A1YFZ4_PANPA MKPNKYGVIYST------PLPEKFFQTPEGLSHGIQMEPVDLTVNK-RSSPPSAGNSPSS KLF3_HUMAN KLF3_HUMAN MKPNKYGVIYST------PLPEKFFQTPEGLSHGIQMEPVDLTVNK-RSSPPSAGNSPSS B8JID2_DANRE B8JID2_DANRE YTEMGVLVLNRR----FRTQPD--DRRFLSDPFQTQTEPVDLSTNKARTSPSLSASSSLS Q6NYX3_DANRE Q6NYX3_DANRE YTEMGVLVLNRR----FRTQPD--DRRFLSDPFQTQTEPVDLSTNKARTSPSLSASSSLS KLF12_MOUSE KLF12_MOUSE YPDMEAVPLLLN--NVKGEPPE--DSLPVD-HFQTQTEPVDLSINKARTSPTAASSSPVS Q6NWV9_MOUSE Q6NWV9_MOUSE YPDMEAVPLLLN--NVKGEPPE--DSLPVD-HFQTQTEPVDLSINKARTSPTAASSSPVS B4YSE9_PIG B4YSE9_PIG YPDMEAVPLLLN--NVKEEPPE--DSLSVD-HFQTQTEPVDLSINKARTSPTAVSSSPVS KLF12_HUMAN KLF12_HUMAN YPDMEAVPLLLN--NVKGEPPE--DSLSVD-HFQTQTEPVDLSINKARTSPTAVSSSPVS Q8WWI3_HUMAN Q8WWI3_HUMAN YPDMEAVPLLLN--NVKGEPPE--DSLSVD-HFQTQTEPVDLSINKARTSPTAVSSSPVS Q4RWC7_TETNG Q4RWC7_TETNG FSAMDSVPFFLS--RVKAETPE--DLLVHDLHFHMQTEPVDLSINKPRPSSSSTTPTTAL A7MBV2_DANRE A7MBV2_DANRE YPDMEAVPLLLS--KVKAEPPE--DLLSSD-QFQTQTEPVDLSINKTRTSSPLSNNSPVT B8JL63_DANRE B8JL63_DANRE YPDMEAVPLLLS--KVKAEPPE--DLLSSD-QFQTQTEPVDLSINKTRTSSPLSNNSPVT A6PWN2_MOUSE A6PWN2_MOUSE ASPMENPALFND---IKIEPPE--ELLESD-FNMPQVEPVDLSFHKPKAPLQPASMLQAP KLF8_MOUSE KLF8_MOUSE ASPMENPALFND---IKIEPPE--ELLESD-FNMPQVEPVDLSFHKPKAPLQPASMLQAP B4YSE6_PIG B4YSE6_PIG INPMENPALLND---IKIEPPE--ELLAND-FNLPQVEPVDLSFHKPKAPLQPASMLQAP Q05BZ3_HUMAN Q05BZ3_HUMAN ANPMENPALFND---IKIEPPE--ELLASD-FSLPQVEPVDLSFHKPKAPLQPASMLQAP B4DJN3_HUMAN B4DJN3_HUMAN ANPMENPALFND---IKIEPPE--ELLASD-FSLPQVEPVDLSFHKPKAPLQPASMLQAP KLF8_HUMAN KLF8_HUMAN ANPMENPALFND---IKIEPPE--ELLASD-FSLPQVEPVDLSFHKPKAPLQPASMLQAP B1H3D6_XENTR B1H3D6_XENTR ASETPTPAFLSD---IKLEPPE--QLLDSD-CSLPQAEPVDLSIHKNQKTSLRQSSSPPS B7ZR90_XENLA B7ZR90_XENLA ASETPTPAFLSD---IKMEPPE--QLLDSD-CSLPQAEPVDLSIHKNQKISLRQSSSPPS Q7T3J7_XENLA Q7T3J7_XENLA ASETPTPAFLSD---IKMEPPE--QLLDSD-CSLPQAEPVDLSIHKNQKISLRQSSSPPS A0S0R1_DANRE A0S0R1_DANRE QEPLDDCLEPTDLKIKSSPPPL--CIISTQHSDADQTEPVDLSLNKPRPSLPIATATSTP B0R0G2_DANRE B0R0G2_DANRE QEPLDDCLEPTDLKIKSSPPPL--CIISTQHSDADQTEPVDLSLNKPRPSLPIATATSTP Q4T2S4_TETNG Q4T2S4_TETNG EVKLEQPRVKTE---RTSPEPD-------------QTEPVDLSLNKPRPSPVPASKASAT MATCH CONSENSUS ????????????????????P??????????????Q?EPVDL???K??????????????

Q4T062_TETNG Q4T062_TETNG CSAASSPV----SSRSSPPSP--------------SPSHALSPPTPSL--PYPMVA---- A2BG67_DANRE A2BG67_DANRE ------------SPRASPPSPYE------------AHSPASRCSQNRQLSPSLTLP---- Q90XE9_DANRE Q90XE9_DANRE ------------SPRASPPSPYE------------AHSPASRCSQNRQLSPSLTLP---- Q6NYD5_DANRE Q6NYD5_DANRE ------------SPRASPPSPYE------------AHSPASRCSQNRQLSPSLTLP---- B4YSE3_PIG B4YSE3_PIG LKFQA-------PHRRASPGLSLPSSSPPAKKYSPPPPPGVQPFSVPLSMPPVMAA---- KLF3_MOUSE KLF3_MOUSE LKFP--------SHRRASPGLSMPSSSPPIKKYS-PPSPGVQPFGVPLSMPPVMAA---- Q545J5_MOUSE Q545J5_MOUSE LKFP--------SHRRASPGLSMPSSSPPIKKYS-PPSPGVQPFGVPLSMPPVMAA---- Q8BV07_MOUSE Q8BV07_MOUSE LKFP--------SHRRASPGLSMPSSSPPIKKYS-PPSPGVQPFGVPLSMPPVMAA---- A1YES7_9PRIM A1YES7_9PRIM LKFPS-------SHRRASPGLSMPSSSPPIKKYS-PPSPGVQPFGVPLSMPPVMAA---- B2R8P9_HUMAN B2R8P9_HUMAN LKFPS-------SHRRASPGLSMPSSSPPIKKYS-PPSPGVQPFGVPLSMPPVMAA---- A1YFZ4_PANPA A1YFZ4_PANPA LKFPS-------SHRRASPGLSMPSSSPPIKKYS-PPSPGVQPFGVPLSMPPVMAA---- KLF3_HUMAN KLF3_HUMAN LKFPS-------SHRRASPGLSMPSSSPPIKKYS-PPSPGVQPFGVPLSMPPVMAA---- B8JID2_DANRE B8JID2_DANRE SSPSSSSSSIRFCPRSPPSSKSLPSSSP-------SSLSMPSSSSTSVITPVPRLKMSPS Q6NYX3_DANRE Q6NYX3_DANRE SSPSSSSSSIRFCPRSSPSSKSLPSSSP-------SSLSMPSSSSTSVITPVPRLKMSPS KLF12_MOUSE KLF12_MOUSE MTGSASSPS---STSTSSSSSSRPASSPTV-----ITSVSRASSSSTVLSPGPLVA---- Q6NWV9_MOUSE Q6NWV9_MOUSE MTASASSPS---STSTSSSSSSRPASSPTV-----ITSVSSASSSSTVLSPGPLVA---- B4YSE9_PIG B4YSE9_PIG MTASASSPS---STSTSSSSSSRPASSPTV-----ITSVSSASSSSTVLTPGPLVA---- KLF12_HUMAN KLF12_HUMAN MTASASSPS---STSTSSSSSSRLASSPTV-----ITSVSSASSSSTVLTPGPLVA---- Q8WWI3_HUMAN Q8WWI3_HUMAN MTASASSPS---STSTSSSSSSRLASSPTV-----ITSVSSASSSSTVLTPGPLVA---- Q4RWC7_TETNG Q4RWC7_TETNG SSSPL-------RYAFSPSSLSSSSSSS-------SSSPSVITSASSVLTSGPLVP---- A7MBV2_DANRE A7MBV2_DANRE SAF---------SPSSSSSSSSSP-----------SVIASVSSGMPSVLTSGSLVG---- B8JL63_DANRE B8JL63_DANRE SAF---------SPSSSSSSSSSP-----------SVIASVSSGMPSVLTSGSLVG---- A6PWN2_MOUSE A6PWN2_MOUSE IRPP--------KPPTAPQAIMVPT----------SADTVTSAAIPTVLTPGSILA---- KLF8_MOUSE KLF8_MOUSE IRPP--------KPPTAPQAIMVPT----------SADTVTSAAIPTVLTPGSILA---- B4YSE6_PIG B4YSE6_PIG IRPP--------KPEPVSQTLVESTS---------TSNTGTSANIPTVLTSGSILA---- Q05BZ3_HUMAN Q05BZ3_HUMAN IRPP--------KPQSSPQTLVVSTS---------TSDMSTSANIPTVLTPGSVLT---- B4DJN3_HUMAN B4DJN3_HUMAN IRPP--------KPQSSPQTLVVSTS---------TSDMSTSANIPTVLTPGSVLT---- KLF8_HUMAN KLF8_HUMAN IRPP--------KPQSSPQTLVVSTS---------TSDMSTSANIPTVLTPGSVLT---- B1H3D6_XENTR B1H3D6_XENTR SSPMVLG-----TPLSAPPSI--------------VSLSGLGSAVPAVLSPGSILA---- B7ZR90_XENLA B7ZR90_XENLA SSPMILE-----TPLSAPPSI--------------MSLSGLGSAIPAVLSPGSILA---- Q7T3J7_XENLA Q7T3J7_XENLA SSPMILE-----TPLSAPPSI--------------MSLSGLGSAIPAVLSPGSILA---- A0S0R1_DANRE A0S0R1_DANRE ANLP-------------------------------PQNITASATIPAVLSQGSILA---- B0R0G2_DANRE B0R0G2_DANRE ANLP-------------------------------PQNITASATIPAVLSQGSILA---- Q4T2S4_TETNG Q4T2S4_TETNG VNP---------APGGTTPGLPAT-----------PVPSAVPSIGSMVLSPGSILA---- MATCH CONSENSUS ??????????????????????????????????????????????????P?????????

Q4T062_TETNG Q4T062_TETNG ---------PLM-GSGSGVIQS----------------------SGVMVSPVMV-PLSVL A2BG67_DANRE A2BG67_DANRE ----------------IPAVTQVLTPFV----------------SSPGMIPVIPMPLSVL Q90XE9_DANRE Q90XE9_DANRE ----------------IPAVTQVLTPFV----------------SSPGMIPVIPMPLSVL Q6NYD5_DANRE Q6NYD5_DANRE ----------------IPAVTQVLTPFV----------------SSPGMIPVIPMPLSVL B4YSE3_PIG B4YSE3_PIG -------ALSRHGGIRSPGILPVIQ-------------------------PVVVQPVPFM KLF3_MOUSE KLF3_MOUSE -------ALSRH-GIRSPGILPVIQ-------------------------PVVVQPVPFM Q545J5_MOUSE Q545J5_MOUSE -------ALSRH-GIRSPGILPVIQ-------------------------PVVVQPVPFM Q8BV07_MOUSE Q8BV07_MOUSE -------ALSRH-GIRSPGILPVIQ-------------------------PVVVQPVPFM A1YES7_9PRIM A1YES7_9PRIM -------ALSRH-GIRSPGILXXIQ-------------------------PVVVQPVPFM B2R8P9_HUMAN B2R8P9_HUMAN -------ALSRH-GIRSPGILPVIQ-------------------------PVVVQPVPFM A1YFZ4_PANPA A1YFZ4_PANPA -------ALSRH-GIRSPGILPVIQ-------------------------PVVVQPVPFM KLF3_HUMAN KLF3_HUMAN -------ALSRH-GIRSPGILPVIQ-------------------------PVVVQPVPFM B8JID2_DANRE B8JID2_DANRE CSVPVVSSLPSR-GLRGQSFLHIPQLMP-PCSSPVHI--------HPRRVPVVVQPMPLV Q6NYX3_DANRE Q6NYX3_DANRE CSVPVVSSLPSR-GLRGQSFLHIPQLMP-PCSSPVHI--------HPRRVPVVVQPMPLV KLF12_MOUSE KLF12_MOUSE ---------SAS-GVGGQQFLHIIHPVP--PSSPMNLQ--SNKLSHVHRIPVVVQSVPVV Q6NWV9_MOUSE Q6NWV9_MOUSE ---------SAS-GVGGQQFLHIIHPVP--PSSPMNLQ--SNKLSHVHRIPVVVQSVPVV B4YSE9_PIG B4YSE9_PIG ---------SAS-GVGGQQFLHIIHPVP--PSSPMNLQ--SNKLSHVHRIPVVVQSVPVV KLF12_HUMAN KLF12_HUMAN ---------SAS-GVGGQQFLHIIHPVP--PSSPMNLQ--SNKLSHVHRIPVVVQSVPVV Q8WWI3_HUMAN Q8WWI3_HUMAN ---------SAS-GVGGQQFLHIIHPVP--PSSPMNLQ--SNKLSHVHRIPVVVQSVPVV Q4RWC7_TETNG Q4RWC7_TETNG ---------PGS-GVRGQPYLHILHSVPPPPSSPLSLPGAGKLASHVHRIPVVVQSLPLM A7MBV2_DANRE A7MBV2_DANRE ---------SSH-GVRGQQFLHIIHPVP--PSSPSKLP------SQVHRISVVVQSLPLM B8JL63_DANRE B8JL63_DANRE ---------SSH-GVRGQQFLHIIHPVP--PSSPSKLP------SQVHRIPVVVQSLPLM A6PWN2_MOUSE A6PWN2_MOUSE ---------SSQ-GTGGQPILHVIHTIP-----SVSLP---NKMSGLKTIPLVVQSLPMV KLF8_MOUSE KLF8_MOUSE ---------SSQ-GTGGQPILHVIHTIP-----SVSLP---NKMSGLKTIPLVVQSLPMV B4YSE6_PIG B4YSE6_PIG ---------SSQ-GTGGQQILHVIHTIP-----SVSLP---NKMSGLKAIPVVVQSLPMV Q05BZ3_HUMAN Q05BZ3_HUMAN ---------SSQ-STGSQQILHVIHTIP-----SVSLP---NKMGGLKTIPVVVQSLPMV B4DJN3_HUMAN B4DJN3_HUMAN ---------SSQ-STGSQQILHVIHTIP-----SVILP---NKMGGLKTIPVVVQSLPMV KLF8_HUMAN KLF8_HUMAN ---------SSQ-STGSQQILHVIHTIP-----SVSLP---NKMGGLKTIPVVVQSLPMV B1H3D6_XENTR B1H3D6_XENTR ---------STQ-GSGGQQILHVIHTIP-----SVNLP---SKMGNLQTIPVVVQSLPVV B7ZR90_XENLA B7ZR90_XENLA ---------STQ-GSGGQQILHVIHTIP-----SVNLP---SKMGNLQTIPVVVQSLPVV Q7T3J7_XENLA Q7T3J7_XENLA ---------STQ-GSGGQQILHVIHTIP-----SVNLP---SKMGNLQTIPVVVQSLPVV A0S0R1_DANRE A0S0R1_DANRE ---------STQ-GVGGQQILHVIHTIP-----SVNMP---SKLGQLQTIPVVVQSLPVV B0R0G2_DANRE B0R0G2_DANRE ---------STQ-GVGGQQILHVIHTIP-----SVNMP---SKLGQLQTIPVVVQSLPVV Q4T2S4_TETNG Q4T2S4_TETNG ----------TQ-GAGGQQILHVIHTIP-----SVSMP---SKVGQLQTIPVVVQSLPVV MATCH .:: .:..: CONSENSUS ?????????????G??????L?????????????????????????????PVVVQ??P??

Q4T062_TETNG Q4T062_TETNG YSSSLHLH------------QPIMVSPSLSSDDDHHRSREHRKVHATKTFDLQGDPHDLH A2BG67_DANRE A2BG67_DANRE YPPSLHLS------------PSIIISPVTP--ED---PANHKHFSVI-KSENTSDHHELL Q90XE9_DANRE Q90XE9_DANRE YPPSLHLS------------PSIIISPVTP--ED---PANHKHFSVI-KSENSSDHHELL Q6NYD5_DANRE Q6NYD5_DANRE YPPSLHLS------------PSIIISPVTP--ED---PANHKHFSVI-KSENSSDHHELL B4YSE3_PIG B4YSE3_PIG YTSHLQQPLMVSLSEEMENSSSSMQVPVIESYEK---PILQK---KI-KIEP-G-----I KLF3_MOUSE KLF3_MOUSE YTSHLQQPLMVSLSEEMDNSNSGMPVPVIESYEK---PLLQK---KI-KIEP-G-----I Q545J5_MOUSE Q545J5_MOUSE YTSHLQQPLMVSLSEEMDNSNSGMPVPVIESYEK---PLLQK---KI-KIEP-G-----I Q8BV07_MOUSE Q8BV07_MOUSE YTSHLQQPLMVSLSEEMDNSNSGMPVPVIESYEK---PLLQK---KI-KIEP-G-----I A1YES7_9PRIM A1YES7_9PRIM YTSHLQQPLMVSLSEEMENSSSSMQVPVIESYEK---PISQK---KI-KIEP-G-----I B2R8P9_HUMAN B2R8P9_HUMAN YTSHLQQPLMVSLSEEMENPSSSMQVPVIESYEK---PISQK---KI-KIEP-G-----I A1YFZ4_PANPA A1YFZ4_PANPA YTSHLQQPLMVSLSEEMENSSSSMQVPVIESYEK---PISQK---KI-KIEP-G-----I KLF3_HUMAN KLF3_HUMAN YTSHLQQPLMVSLSEEMENSSSSMQVPVIESYEK---PISQK---KI-KIEP-G-----I B8JID2_DANRE B8JID2_DANRE YP-GVGSL---------GS--SRLMMPLL---EE---NRMHR---KVMHRMADG-----L Q6NYX3_DANRE Q6NYX3_DANRE YP-GVGSL---------GS--SRLMMPLL---EE---NRMHR---KVMHRMADG-----L KLF12_MOUSE KLF12_MOUSE YT-AVRSP---------GNVNNTIVVPLL---ED---GRSHG---KA-QMEPRG-----L Q6NWV9_MOUSE Q6NWV9_MOUSE YT-AVRSP---------GNVNNTIVVPLL---ED---GRSHG---KA-QMEPRG-----L B4YSE9_PIG B4YSE9_PIG YT-AVRSP---------GNVNNTIVVPLL---ED---GRSHG---KA-QMDPRG-----L KLF12_HUMAN KLF12_HUMAN YT-AVRSP---------GNVNNTIVVPLL---ED---GRGHG---KA-QMDPRG-----L Q8WWI3_HUMAN Q8WWI3_HUMAN YT-AVRSP---------GNVNNTIVVPLL---ED---GRGHG---KA-QMDPRG-----L Q4RWC7_TETNG Q4RWC7_TETNG YTSAVRSP---------SSLNNAIMLPLL---DE---VKGQG---KA-HLDHNG-----L A7MBV2_DANRE A7MBV2_DANRE YTTSVRSP---------STLSSTIMLPLL---DE---ARCQD---KA-QTDPNG-----L B8JL63_DANRE B8JL63_DANRE YTTSVRSP---------STLSSTIMLPLL---DE---ARCQD---KA-QTDPNG-----L A6PWN2_MOUSE A6PWN2_MOUSE YT-SLPTD---------GS-PAAITVPLIG--GD---GKSAG---SV-KVDPAS-----M KLF8_MOUSE KLF8_MOUSE YT-SLPTD---------GS-PAAITVPLIG--GD---GKSAG---SV-KVDPAS-----M B4YSE6_PIG B4YSE6_PIG YT-TLPAD---------GG-PAAITVPLIG--GD---GKNAG---SV-KVDPTS-----M Q05BZ3_HUMAN Q05BZ3_HUMAN YT-TLPAD---------GG-PAAITVPLIG--GD---GKNAG---SG------------- B4DJN3_HUMAN B4DJN3_HUMAN YT-TLPAD---------GG-PAAITVPLIG--GD---GKNAG---SV-KVDPTS-----M KLF8_HUMAN KLF8_HUMAN YT-TLPAD---------GG-PAAITVPLIG--GD---GKNAG---SV-KVDPTS-----M B1H3D6_XENTR B1H3D6_XENTR YT-TLPTD---------GM-TAALTVPLLG--PD---GKVTGRSHNL-LMRSQA-----S B7ZR90_XENLA B7ZR90_XENLA YT-TLPTD---------GV-TAALTVPILG--SD---GKGTGRSHNL-LMRSST-----S Q7T3J7_XENLA Q7T3J7_XENLA YT-TLPTD---------GV-TAALTVPILG--SD---GKGTGRSHNL-LMRSST-----S A0S0R1_DANRE A0S0R1_DANRE YT-TVPTD---------GMATAAITVPLIG--SD---GRSEG---SV-RIKPGS-----T B0R0G2_DANRE B0R0G2_DANRE YT-TVPTD---------GMATAAITVPLIG--SD---GRSEG---SV-RIKPGS-----T Q4T2S4_TETNG Q4T2S4_TETNG YT-TVPTD---------GVATAAITVPLIG--SD---GRSEG---SV-RIKPGS-----T MATCH *. : : * . CONSENSUS YT????????????????????????P?????????????????????????????????

Q4T062_TETNG Q4T062_TETNG KSIKTEARPECSGDI----NGGHKAKTSVIRIPQEYGG--------------------NN A2BG67_DANRE A2BG67_DANRE KPIKSEPHP----------EHTQDNHSQEKSVI-------------------------TA Q90XE9_DANRE Q90XE9_DANRE KPIKSEPHP----------EHTQDNHSQEKSVI-------------------------TA Q6NYD5_DANRE Q6NYD5_DANRE KPIKSEPHP----------EHTQDNHSQEKSVI-------------------------TA B4YSE3_PIG B4YSE3_PIG EPQRTDYYP----------EEMSPPLMNSVSPPQALLQ--------------------EN KLF3_MOUSE KLF3_MOUSE EPQRTDYYP----------EEMSPPLMNPVSPPQALLQ--------------------EN Q545J5_MOUSE Q545J5_MOUSE EPQRTDYYP----------EEMSPPLMNPVSPPQALLQ--------------------EN Q8BV07_MOUSE Q8BV07_MOUSE EPQRTDYYP----------EEMSPPLMNPVSPPQALLQ--------------------EN A1YES7_9PRIM A1YES7_9PRIM EPQRTDYYP----------EEMSPPLMNSVSPPQALLQ--------------------EN B2R8P9_HUMAN B2R8P9_HUMAN EPQRTDYYP----------EEMSPPLMNSVSPPQALLQ--------------------EN A1YFZ4_PANPA A1YFZ4_PANPA EPQRTDYYP----------EEMSPPLMNSVSPPQALLQ--------------------EN KLF3_HUMAN KLF3_HUMAN EPQRTDYYP----------EEMSPPLMNSVSPPQALLQ--------------------EN B8JID2_DANRE B8JID2_DANRE SPRRSLSDSEDDDLPNVTLESVNETGSTALTIARAVQD---------------------S Q6NYX3_DANRE Q6NYX3_DANRE SPRRSLSDSEDDDLPNVTLESVNETGSTALTIARAVQD---------------------S KLF12_MOUSE KLF12_MOUSE SPRQSKSDSDDDDLPNVTLDSVNETGSTALSIARAVQEVHPSPVSRVRGNRMNNQKFACS Q6NWV9_MOUSE Q6NWV9_MOUSE SPRQSKSDSDDDDLPNVTLDSVNETGSTALSIARAVQEVHPSPVSRVRGNRMNNQKFACS B4YSE9_PIG B4YSE9_PIG SPRQSKSDSDDDDLPNVTLDSVNETGSTALSIARAVQEVHPSPVSRVRGNRMNNQKFACS KLF12_HUMAN KLF12_HUMAN SPRQSKSDSDDDDLPNVTLDSVNETGSTALSIARAVQEVHPSPVSRVRGNRMNNQKFPCS Q8WWI3_HUMAN Q8WWI3_HUMAN SPRQSKSDSDDDDLPNVTLDSVNETGSTALSIARAVQEVHPSPVSRVRGNRMNNQKFPCS Q4RWC7_TETNG Q4RWC7_TETNG SPRQIKSDSDDDDLPNVTLDSVNETGSTALSIARAVQEGQKSRWREGRVASLD-----SS A7MBV2_DANRE A7MBV2_DANRE SPRQIKSDSDDDDLPNVTLDSVNETGSTALSIARAVQD---------------------S B8JL63_DANRE B8JL63_DANRE SPRQIKSDSDDDDLPNVTLDSVNETGSTALSIARAVQD---------------------S A6PWN2_MOUSE A6PWN2_MOUSE CPLEFPSDSD---------ESAIESGSSALQSLQGFHH--------------------EP KLF8_MOUSE KLF8_MOUSE CPLEFPSDSD---------ESAIESGSSALQSLQGFHH--------------------EP B4YSE6_PIG B4YSE6_PIG SPLEIPSDSE---------ENAIESGSSALQGIQGLQQ--------------------EP Q05BZ3_HUMAN Q05BZ3_HUMAN ------------------------------------------------------------ B4DJN3_HUMAN B4DJN3_HUMAN SPLEIPSDSE---------ESTIESGSSALQSLQGLQQ---------------------- KLF8_HUMAN KLF8_HUMAN SPLEIPSDSE---------ESTIESGSSALQSLQGLQQ--------------------EP B1H3D6_XENTR B1H3D6_XENTR EVEDFDLRAD---------QSPCDLGSMSLSAHSSVKAELESPVEINSDSDDSIVEASPS B7ZR90_XENLA B7ZR90_XENLA EVEDSDSRAD---------QSPNDLGSMSLSAHSSVKADPESPVEINSDSDDSIVETSSS Q7T3J7_XENLA Q7T3J7_XENLA EVEDSDSRAD---------QSPNDLGSMSLSAHSSVKADPESPVEINSDSDDSIVETSSS A0S0R1_DANRE A0S0R1_DANRE SPVEYQSESDA--------ESGTESGSASFSTQ--------------------------G B0R0G2_DANRE B0R0G2_DANRE SPVEYQSESDA--------ESGTESGSASFSTQ--------------------------G Q4T2S4_TETNG Q4T2S4_TETNG SP-EYQSESDA--------ESGTESETASLRAQ--------------------------S MATCH CONSENSUS ?P??????????????????????????????????????????????????????????

Q4T062_TETNG Q4T062_TETNG PSVIVHSGTQHPVP---AESPDTLKKRRIHRCDFSGCNKVYTKSSHLKAHRRTHT----- A2BG67_DANRE A2BG67_DANRE LPNYNDRGNTQSPK---VESPDLLKKRRIHRCDFNGCNKVYTKSSHLKAHRRTHT----- Q90XE9_DANRE Q90XE9_DANRE LPTYNDRGNTQSPK---VESPDLLNKRRIHRCDFNGCNKVYTKSSHLKAHRRTHT----- Q6NYD5_DANRE Q6NYD5_DANRE LPTYNDRGNTQSPK---VESPDLLKKRRIHRCDFNGCNKVYTKSSHLKAHRRTHT----- B4YSE3_PIG B4YSE3_PIG HPSVIVQPGKRPLP---VESPDTQRKRRIHRCDYDGCNKVYTKSSHLKAHRRTHT----- KLF3_MOUSE KLF3_MOUSE HPSVIVQPGKRPLP---VESPDTQRKRRIHRCDYDGCNKVYTKSSHLKAHRRTHT----- Q545J5_MOUSE Q545J5_MOUSE HPSVIVQPGKRPLP---VESPDTQRKRRIHRCDYDGCNKVYTKSSHLKAHRRTHT----- Q8BV07_MOUSE Q8BV07_MOUSE HPSVIVQPGKRPLP---VESPDTQRKRRIHRCDYDGCNKVYTKSSHLKAHRRTHT----- A1YES7_9PRIM A1YES7_9PRIM HPSVIVQPGKRPLP---VESPDTQRKRRIHRCDYDGCNKVYTKSSHLKAHRRTHT----- B2R8P9_HUMAN B2R8P9_HUMAN HPSVIVQPGKRPLP---VESPDTQRKRRIHRCDYDGCNKVYTKSSHLKAHRRTHT----- A1YFZ4_PANPA A1YFZ4_PANPA HPSVIVQPGKRPLP---VESPDTQRKRRIHRCDYDGCNKVYTKSSHLKAHRRTHT----- KLF3_HUMAN KLF3_HUMAN HPSVIVQPGKRPLP---VESPDTQRKRRIHRCDYDGCNKVYTKSSHLKAHRRTHT----- B8JID2_DANRE B8JID2_DANRE LLPFSIESLRRPRP---SESPDS-KRRRIHRCEFEGCNKVYTKSSHLKAHRRTHT----- Q6NYX3_DANRE Q6NYX3_DANRE LLPFSIESLRRPRP---SESPDS-KRRRIHRCEFEGCNKVYTKSSHLKAHRRTHT----- KLF12_MOUSE KLF12_MOUSE ISPFSIESTRRQRR---SESPDS-RKRRIHRCDFEGCNKVYTKSSHLKAHRRTHT----- Q6NWV9_MOUSE Q6NWV9_MOUSE ISPFSIESTRRQRR---SESPDS-RKRRIHRCDFEGCNKVYTKSSHLKAHRRTHT----- B4YSE9_PIG B4YSE9_PIG ISPFSIESTRRQRR---SESPDS-RKRRIHRCDFEGCNKVYTKSSHLKAHRRTHT----- KLF12_HUMAN KLF12_HUMAN ISPFSIESTRRQRR---SESPDS-RKRRIHRCDFEGCNKVYTKSSHLKAHRRTHT----- Q8WWI3_HUMAN Q8WWI3_HUMAN ISPFSIESTRRQRR---SESPDS-RKRRIHRCDFEGCNKVYTKSSHLKAHRRTHT----- Q4RWC7_TETNG Q4RWC7_TETNG MSPFSIDSIRRPRR---SESPDS-KKRRIHRCDFDGCNKVYTKSSHLKAHRRTHT----- A7MBV2_DANRE A7MBV2_DANRE MSPFSIESIRRPPP---PESPDS-KKRRIHRCDFAGCNKVYTKSSHLKAHRRTHT----- B8JL63_DANRE B8JL63_DANRE MSPFSIESIRRPPP---PESPDS-KKRRIHRCDFAGCNKVYTKSSHLKAHRRTHT----- A6PWN2_MOUSE A6PWN2_MOUSE ATMVHMQG---------EESLDL-KRRRIHQCDFAGCSKVYTKSSHLKAHRRIHT----- KLF8_MOUSE KLF8_MOUSE ATMVHMQG---------EESLDL-KRRRIHQCDFAGCSKVYTKSSHLKAHRRIHT----- B4YSE6_PIG B4YSE6_PIG AVMTQMQG---------EESLDL-KRRRIHQCDFAGCSKVYTKSSHLKAHRRIHT----- Q05BZ3_HUMAN Q05BZ3_HUMAN ------------------------------------------------------------ B4DJN3_HUMAN B4DJN3_HUMAN ------------------------EREAL------------------------------- KLF8_HUMAN KLF8_HUMAN AAMAQMQGEE---------SLDL-KRRRIHQCDFAGCSKVYTKSSHLKAHRRIHT----- B1H3D6_XENTR B1H3D6_XENTR FPDTAHGTRLMRMQRGGAGSPDM-RKRRVHQCDFEGCNKVYTKSSHLKAHRRIHT----- B7ZR90_XENLA B7ZR90_XENLA FPDTAHGPRFTRMQRGGAGSPDT-RKRRVHQCDFEGCNKVYTKSSHLKAHRRIHT----- Q7T3J7_XENLA Q7T3J7_XENLA FPDTAHGPRFTRMQRGGAGSPDT-RKRRVHQCDFEGCNKVYTKSSHLKAHRRIHT----- A0S0R1_DANRE A0S0R1_DANRE MEPSINTDVDIPAD---PDSPDM-KRRRVHMCDYDGCNKVYTKSSHLKAHRRIHT----- B0R0G2_DANRE B0R0G2_DANRE MEPSINTDVDIPAD---PDSPDM-KRRRVHMCDYDGCNKVYTKSSHLKAHRRIHT----- Q4T2S4_TETNG Q4T2S4_TETNG LDAGSVMDLE-PVD---PDSPDI-KRRRIHMCDYEGCKKVYTKSSHLKAHRRLHTGEAAA MATCH CONSENSUS ???????????????????SPD????RR?H?CD??GC?KVYTKSSHLKAHRR?HT?????

Q4T062_TETNG Q4T062_TETNG -------------------GEKPYKCMWEGCTWKFARSDELTRHFRKHTGVKPFQCPRLR A2BG67_DANRE A2BG67_DANRE -------------------GEKPYKCMWEGCTWKFARSDELTRHYRKHTGVKPFHCPDCD Q90XE9_DANRE Q90XE9_DANRE -------------------GEKPYKCMWEGCTWKFARSDELTRHYRKHTGVKPFHCPDCD Q6NYD5_DANRE Q6NYD5_DANRE -------------------GEKPYKCMWEGCTWKFARSDELTRHYRKHTGVKPFHCPDCD B4YSE3_PIG B4YSE3_PIG -------------------GEKPYKCTWEGCTWKFARSDELTRHFRKHTGIKPFQCPDCD KLF3_MOUSE KLF3_MOUSE -------------------GEKPYKCTWEGCTWKFARSDELTRHFRKHTGIKPFQCPDCD Q545J5_MOUSE Q545J5_MOUSE -------------------GEKPYKCTWEGCTWKFARSDELTRHFRKHTGIKPFQCPDCD Q8BV07_MOUSE Q8BV07_MOUSE -------------------GEKPYKCTWEGCTWKFARSDELTRHFRKHTGIKPFQCPDCD A1YES7_9PRIM A1YES7_9PRIM ------------------------------------------------------------ B2R8P9_HUMAN B2R8P9_HUMAN -------------------GEKPYKCTWEGCTWKFARSDELTRHFRKHTGIKPFQCPDCD A1YFZ4_PANPA A1YFZ4_PANPA ------------------------------------------------------------ KLF3_HUMAN KLF3_HUMAN -------------------GEKPYKCTWEGCTWKFARSDELTRHFRKHTGIKPFQCPDCD B8JID2_DANRE B8JID2_DANRE -------------------GEKPYKCTWDNCTWKFARSDELTRHYRKHTGVKPFKCSDCD Q6NYX3_DANRE Q6NYX3_DANRE -------------------GEKPYKCTWDNCTWKFARSDELTRHYRKHTGVKPFKCSDCD KLF12_MOUSE KLF12_MOUSE -------------------GEKPYKCTWEGCTWKFGRSDELTRHYRKHTGVKPFKCADCD Q6NWV9_MOUSE Q6NWV9_MOUSE -------------------GEKPYKCTWEGCTWKFARSDELTRHYRKHTGVKPFKCADCD B4YSE9_PIG B4YSE9_PIG -------------------GEKPYKCTWEGCTWKFARSDELTRHYRKHTGVKPFKCADCD KLF12_HUMAN KLF12_HUMAN -------------------GEKPYKCTWEGCTWKFARSDELTRHYRKHTGVKPFKCADCD Q8WWI3_HUMAN Q8WWI3_HUMAN -------------------GEKPYKCTWEGCTWKFARSDELTRHYRKHTGVKPFKCADCD Q4RWC7_TETNG Q4RWC7_TETNG -------------------GEKPYKCTWEGCTWKFARSDELTRHYRKHTGVKPFKCADCD A7MBV2_DANRE A7MBV2_DANRE -------------------GEKPYKCTWDGCTWKFARSDELTRHYRKHTGVKPFKCGDCD B8JL63_DANRE B8JL63_DANRE -------------------GEKPYKCTWDGCTWKFARSDELTRHYRKHTGVKPFKCGDCD A6PWN2_MOUSE A6PWN2_MOUSE -------------------GEKPYKCTWDGCSWKFARSDELTRHFRKHTGIKPFRCTDCN KLF8_MOUSE KLF8_MOUSE -------------------GEKPYKCTWDGCSWKFARSDELTRHFRKHTGIKPFRCTDCN B4YSE6_PIG B4YSE6_PIG -------------------GEKPYKCTWDGCSWKFARSDELTRHFRKHTGIKPFRCTDCN Q05BZ3_HUMAN Q05BZ3_HUMAN -------------------AQRP--------RWMFSHLD--------------------- B4DJN3_HUMAN B4DJN3_HUMAN ------------------------------------------------------------ KLF8_HUMAN KLF8_HUMAN -------------------GEKPYKCTWDGCSWKFARSDELTRHFRKHTGIKPFRCTDCN B1H3D6_XENTR B1H3D6_XENTR -------------------GEKPYKCTWEGCTWKFARSDELTRHFRKHTGIKPFLCSDCD B7ZR90_XENLA B7ZR90_XENLA -------------------GEKPYKCTWLGCTWKFARSDELTRHFRKHTGVKPFLCLDCD Q7T3J7_XENLA Q7T3J7_XENLA -------------------GEKPYKCTWLGCTWKFARSDELTRHFRKHTGVKPFLCLDCD A0S0R1_DANRE A0S0R1_DANRE -------------------GEKPYQCTWEGCTWRFARSDELTRHFRKHTGIKPFRCTDCD B0R0G2_DANRE B0R0G2_DANRE -------------------GEKPYQCTWEGCTWRFARSDELTRHFRKHTGIKPFRCTDCD Q4T2S4_TETNG Q4T2S4_TETNG AKRRGARGPLTGANGRCAAGEKPYHCTWEGCTWRFARSDELTRHFRKHTGIKPFRCTECD MATCH CONSENSUS ???????????????????GEKPY?C?W?GC?W?FARSDELTRH?RKHTG?KPF?C?DC?

Q4T062_TETNG Q4T062_TETNG AQLLPAPTTWLCTRSAT-YWCET A2BG67_DANRE A2BG67_DANRE RTFSRSDHLALHKKRH----LLV Q90XE9_DANRE Q90XE9_DANRE RTFSRSDHLALHKKRH----LLV Q6NYD5_DANRE Q6NYD5_DANRE RTFSRSDHLALHKKRH----LLV B4YSE3_PIG B4YSE3_PIG RSFSRSDHLALHRKRH----MLV KLF3_MOUSE KLF3_MOUSE RSFSRSDHLALHRKRH----MLV Q545J5_MOUSE Q545J5_MOUSE RSFSRSDHLALHRKRH----MLV Q8BV07_MOUSE Q8BV07_MOUSE RSFSRSDHLALHRKRH----MLV A1YES7_9PRIM A1YES7_9PRIM ----------------------- B2R8P9_HUMAN B2R8P9_HUMAN RSFSRSDHLALHRKRH----MLV A1YFZ4_PANPA A1YFZ4_PANPA ----------------------- KLF3_HUMAN KLF3_HUMAN RSFSRSDHLALHRKRH----MLV B8JID2_DANRE B8JID2_DANRE RSFSRSDHLALHRRRHAPQTCLV Q6NYX3_DANRE Q6NYX3_DANRE RSFSRSDHLALHRRRHAPQTCLV KLF12_MOUSE KLF12_MOUSE RRFSRSDHLALHRRRH----MLV Q6NWV9_MOUSE Q6NWV9_MOUSE RSFSRSDHLALHRRRH----MLV B4YSE9_PIG B4YSE9_PIG RSFSRSDHLALHRRRH----MLV KLF12_HUMAN KLF12_HUMAN RSFSRSDHLALHRRRH----MLV Q8WWI3_HUMAN Q8WWI3_HUMAN RSFSRSDHLALHRRRH----MLV Q4RWC7_TETNG Q4RWC7_TETNG RSSSRSDHWPLHRRRH----MLV A7MBV2_DANRE A7MBV2_DANRE RSFSRSDHLALHRRRH----MLV B8JL63_DANRE B8JL63_DANRE RSFSRSDHLALHRRRH----MLV A6PWN2_MOUSE A6PWN2_MOUSE RSFSRSDHLSLHRRRH----DTM KLF8_MOUSE KLF8_MOUSE RSFSRSDHLSLHRRRH----DTM B4YSE6_PIG B4YSE6_PIG RSFSRSDHLSLHRRRH----DTM Q05BZ3_HUMAN Q05BZ3_HUMAN ----------------------- B4DJN3_HUMAN B4DJN3_HUMAN ----------------------- KLF8_HUMAN KLF8_HUMAN RSFSRSDHLSLHRRRH----DTM B1H3D6_XENTR B1H3D6_XENTR RSFSRSDHLALHRRRH----IMM B7ZR90_XENLA B7ZR90_XENLA RSFSRSDHLALHRRRH----IMM Q7T3J7_XENLA Q7T3J7_XENLA RSFSRSDHLALHRRRH----IMM A0S0R1_DANRE A0S0R1_DANRE RSFSRSDHLALHRRRH----VMM B0R0G2_DANRE B0R0G2_DANRE RSFSRSDHLALHRRRH----VMM Q4T2S4_TETNG Q4T2S4_TETNG RSFSRSDHLSLHRRRH----VMM MATCH CONSENSUS R?FSRSDHL?LH??RH???????


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