Alignment of the gene Family HBG005032 of HOVERGEN

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Threshold: 50% 80% 100%
Size: Bigger Smaller Normal
Isoforms are ON
IL9R_HUMAN IL9R_HUMAN GLGRCIWE-----GWTLESEALRRDMGTWLLACICICTCVCLGVSVTGE-GQGPRSRTFT Q63216_RAT Q63216_RAT ALGRCFPE-----GCTVEGAAVKQV--SWFLIYSCVCSCVCWGVSVPAQ-EGGRKAGTFT B7ZD65_MOUSE B7ZD65_MOUSE ALGRCIAEVLFFAGWTLERVAVKQV--SWFLIYSWVCSGVCRGVSVPEQGGGGQKAGAFT A2AVE0_MOUSE A2AVE0_MOUSE ALGRCIAE-----GWTLERVAVKQV--SWFLIYSWVCSGVCRGVSVPEQGGGGQKAGAFT IL9R_MOUSE IL9R_MOUSE ALGRCIAE-----GWTLERVAVKQV--SWFLIYSWVCSGVCRGVSVPEQGGGGQKAGAFT Q78PA5_MOUSE Q78PA5_MOUSE ALGRCIAE-----GWTLERVAVKQV--SWFLIYSWVCSGVCRGVSVPEQGGGGQKAGAFT Q2M2M3_MOUSE Q2M2M3_MOUSE ALGRCIAEVLFFAGWTLERVAVKQV--SWFLIYSWVCSGVCRGVSVPEQGGGGQKAGAFT Q8C2G1_MOUSE Q8C2G1_MOUSE ALGRCIAE-----GWTLERVAVKQV--SWFLIYSWVCSGVCRGVSVPEQGGGGQKAGAFT MATCH .****: * * *:* *::: :*:* :*: ** ****. : * :: :** CONSENSUS ALGRCI?E?????GWTLE??AVKQV??SWFLIYS?VCS?VC?GVSVP?Q?GGG?KAG?FT

IL9R_HUMAN IL9R_HUMAN CLTNNILRIDCHWSAPELGQGSSPWLLFTSNQAPGGTHKCILRGSECTVVLPPEAVLVPS Q63216_RAT Q63216_RAT CFSNSVFRIDCHWSAPEPG--SRAWLLFTSNQGTDIKHKCTFWDSRCTLVLPKEEAFLPF B7ZD65_MOUSE B7ZD65_MOUSE CLSNSIYRIDCHWSAPELGQESRAWLLFTSNQVTEIKHKCTFWDSMCTLVLPKEEVFLPF A2AVE0_MOUSE A2AVE0_MOUSE CLSNSIYRIDCHWSAPELGQESRAWLLFTSNQVTEIKHKCTFWDSMCTLVLPKEEVFLPF IL9R_MOUSE IL9R_MOUSE CLSNSIYRIDCHWSAPELGQESRAWLLFTSNQVTEIKHKCTFWDSMCTLVLPKEEVFLPF Q78PA5_MOUSE Q78PA5_MOUSE CLSNSIYRIDCHWSAPELGQESRAWLLFTSNQVTEIKHKCTFWDSMCTLVLPKEEVFLPF Q2M2M3_MOUSE Q2M2M3_MOUSE CLSNSIYRIDCHWSAPELGQESRAWLLFTSNQVTEIKHKCTFWDSMCTLVLPKEEVFLPF Q8C2G1_MOUSE Q8C2G1_MOUSE CLSNSIYRIDCHWSAPELGQESRAWLLFTSNQVTEIKHKCTFWDSMCTLVLPKEEVFLPF MATCH *::*.: ********** * * .******** . .*** : .* **:*** * .::* CONSENSUS CLSNSI?RIDCHWSAPELGQ?SRAWLLFTSNQ?T?IKHKCTFWDS?CTLVLPKEEVFLPF

IL9R_HUMAN IL9R_HUMAN DNFTITFHHCMSGREQVSLVDPEYLPRRHVKLDPPSDLQSNISSGHCILTWSISPALEPM Q63216_RAT Q63216_RAT DNFTITLHRCVMGQEQVSLVDSQYLPRRHIKLDPPSDLQSNVSSGRCVLTWGISFGLEPL B7ZD65_MOUSE B7ZD65_MOUSE DNFTITLHRCIMGQEQVSLVDSQYLPRRHIKLDPPSDLQSNVSSGRCVLTWGINLALEPL A2AVE0_MOUSE A2AVE0_MOUSE DNFTITLHRCIMGQEQVSLVDSQYLPRRHIKLDPPSDLQSNVSSGRCVLTWGINLALEPL IL9R_MOUSE IL9R_MOUSE DNFTITLHRCIMGQEQVSLVDSQYLPRRHIKLDPPSDLQSNVSSGRCVLTWGINLALEPL Q78PA5_MOUSE Q78PA5_MOUSE DNFTITLHRCIMGQEQVSLVDSQYLPRRHIKLDPPSDLQSNVSSGRCVLTWGINLALEPL Q2M2M3_MOUSE Q2M2M3_MOUSE DNFTITLHRCIMGQEQVSLVDSQYLPRRHIKLDPPSDLQSNVSSGRCVLTWGINLALEPL Q8C2G1_MOUSE Q8C2G1_MOUSE DNFTITLHRCIMGQEQVSLVDSQYLPRRHIKLDPPSDLQSNVSSGRCVLTWGINLALEPL MATCH ******:*:*: *:*******.:******:***********:***:*:***.*. .***: CONSENSUS DNFTITLHRC?MGQEQVSLVDSQYLPRRHIKLDPPSDLQSNVSSGRCVLTWGI??ALEPL

IL9R_HUMAN IL9R_HUMAN TTLLSYELAFKKQEEAWEQAQHRDHIVGVTWLILEAFELDPGFIHEARLRVQMATLE--D Q63216_RAT Q63216_RAT ITSLSYELAFKRQEEAWEQARLKDRIVGVTWLVLEAIELNPDTIYEARLRVQM-ALESYD B7ZD65_MOUSE B7ZD65_MOUSE ITSLSYELAFKRQEEAWEQARHKDRIVGVTWLILEAVELNPGSIYEARLRVQM-TLESYE A2AVE0_MOUSE A2AVE0_MOUSE ITSLSYELAFKRQEEAWEQARHKDRIVGVTWLILEAVELNPGSIYEARLRVQM-TLESYE IL9R_MOUSE IL9R_MOUSE ITSLSYELAFKRQEEAWE-ARHKDRIVGVTWLILEAVELNPGSIYEARLRVQM-TLESYE Q78PA5_MOUSE Q78PA5_MOUSE ITSLSYELAFKRQEEAWE-ARHKDRIVGVTWLILEAVELNPGSIYEARLRVQM-TLESYE Q2M2M3_MOUSE Q2M2M3_MOUSE ITSLSYELAFKRQEEAWEQARHKDRIVGVTWLILEAVELNPGSVYEARLRVQM-TLESYE Q8C2G1_MOUSE Q8C2G1_MOUSE ITSLSYELAFKRQEEAWEQARHKDRIVGVTWLILEAVELNPGSIYEARLRVQM-TLESYE MATCH * ********:****** *: :*:*******:***.**:*. ::******** :** : CONSENSUS ITSLSYELAFKRQEEAWE?ARHKDRIVGVTWLILEA?ELNPG?IYEARLRVQM?TLESY?

IL9R_HUMAN IL9R_HUMAN DVVEEERYTGQWSEWSQPVCFQAPQR--QGPLIPPWGWPGNTLVAVSIFLLLTGPTYLLF Q63216_RAT Q63216_RAT DKTEGEYYKSHWSEWSQSVSFPSPRRKTQGLLIPRWQGSASILVAVPIFLLLTGLIHFLF B7ZD65_MOUSE B7ZD65_MOUSE DKTEGEYYKSHWSEWSQPVSFPSPQRR-QGLLVPRWQWSASILVVVPIFLLLTGFVHLLF A2AVE0_MOUSE A2AVE0_MOUSE DKTEGEYYKSHWSEWSQPVSFPSPQRR-QGLLVPRWQWSASILVVVPIFLLLTGFVHLLF IL9R_MOUSE IL9R_MOUSE DKTEGEYYKSHWSEWSQPVSFPSPQRR-QGLLVPRWQWSASILVVVPIFLLLTGFVHLLF Q78PA5_MOUSE Q78PA5_MOUSE DKTEGEYYKSHWSEWSQPVSFPSPQRR-QGLLVPRWQWSASILVVVPIFLLLTGFVHLLF Q2M2M3_MOUSE Q2M2M3_MOUSE DKTEGEYYKSHWSEWSQPVSFPSPQRR-QGLLVPRWQWSASILVVVPIFLLLTGFVHLLF Q8C2G1_MOUSE Q8C2G1_MOUSE DKTEGEYYKSHWSEWSQPVSFPSPQRR-QGLLVPRWQWSASILVVVPIFLLLTGFVHLLF MATCH * .* * *..:******.*.* :*:* ** *:* * ... **.*.******* ::** CONSENSUS DKTEGEYYKSHWSEWSQPVSFPSPQR??QGLL?PRWQWSASILV?VPIFLLLTG??HLLF

IL9R_HUMAN IL9R_HUMAN KLSPRVKRIFYQNVPSPAMFFQPLYSVHNGNFQTWMGAHGAGVLLSQDCAGTPQGALEPC Q63216_RAT Q63216_RAT RLSPKVKRIFYQNVPSPEAFFHPLYSVYHGDFQTWIGARRAGPQARQDGASAPSGDSESS B7ZD65_MOUSE B7ZD65_MOUSE KLSPRLKRIFYQNIPSPEAFFHPLYSVYHGDFQSWTGARRAGPQARQNGVSTSSAGSESS A2AVE0_MOUSE A2AVE0_MOUSE KLSPRLKRIFYQNIPSPEAFFHPLYSVYHGDFQSWTGARRAGPQARQNGVSTSSAGSESS IL9R_MOUSE IL9R_MOUSE KLSPRLKRIFYQNIPSPEAFFHPLYSVYHGDFQSWTGARRAGPQARQNGVSTSSAGSESS Q78PA5_MOUSE Q78PA5_MOUSE KLSPRLKRIFYQNIPSPEAFFHPLYSVYHGDFQSWTGARRAGPQARQNGVSTSSAGSESS Q2M2M3_MOUSE Q2M2M3_MOUSE KLSPRLKRIFYQNIPSPEAFFHPLYSVYHGDFQTWTGAHRAGPQARQNGVSTSSAGSESS Q8C2G1_MOUSE Q8C2G1_MOUSE KLSPRLKRIFYQNIPSPEAFFHPLYSVYHGDFQTWTGAHRAGPQARQNGVSTSSAGSESS MATCH :***::*******:*** **:*****::*:**:* **: ** *: ..:... *.. CONSENSUS KLSPR?KRIFYQN?PSPEAFFHPLYSVYHGDFQ?W?GA?RAGPQARQ?G?ST?S??SESS

IL9R_HUMAN IL9R_HUMAN VQEATALLTCGPARPWKSVALEEEQEGPGTRLPGNLSSEDVLPAGCTEWRVQTLAYLPQE Q63216_RAT Q63216_RAT IWEAIATLTYSPACSVQFPSLKWEATAPG--FPGPPGSELVLPAGCLELEGQPSAYLPQE B7ZD65_MOUSE B7ZD65_MOUSE IWEAVATLTYSPACPVQFACLKWEATAPG--FPGLPGSEHVLPAGCLELEGQPSAYLPQE A2AVE0_MOUSE A2AVE0_MOUSE IWEAVATLTYSPACPVQFACLKWEATAPG--FPGLPGSEHVLPAGCLELEGQPSAYLPQE IL9R_MOUSE IL9R_MOUSE IWEAVATLTYSPACPVQFACLKWEATAPG--FPGLPGSEHVLPAGCLELEGQPSAYLPQE Q78PA5_MOUSE Q78PA5_MOUSE IWEAVATLTYSPACPVQFACLKWEATAPG--FPGLPGSEHVLPAGCLELEGQPSAYLPQE Q2M2M3_MOUSE Q2M2M3_MOUSE IWEAIATLTYSPACPVQFACLKWEATAPG--FPGPPGSEHVLPAGCLELEGQPSAYLPQE Q8C2G1_MOUSE Q8C2G1_MOUSE IWEAIATLTYSPACPVQFACLKWEATAPG--FPGPPGSEHVLPAGCLELEGQPSAYLPQE MATCH : ** * ** .** . : .*: * .** :** .** ****** * . *. ****** CONSENSUS IWEA?ATLTYSPACPVQF??LKWEATAPG??FPG?PGSE?VLPAGCLELEGQPSAYLPQE

IL9R_HUMAN IL9R_HUMAN DWAPTSLTRPAPPDSEGSRSSSSSSSSNNNNYCALGCYGGWHLSALPGNTQSSGPIPALA Q63216_RAT Q63216_RAT DWAPLGSARPPPLDSD----------SGSSDYCMLDCREEYDLSVFPEHTLSPEFTLAQP B7ZD65_MOUSE B7ZD65_MOUSE DWAPLGSARPPPPDSD----------SGSSDYCMLDCCEECHLSAFPGHTESPELTLAQP A2AVE0_MOUSE A2AVE0_MOUSE DWAPLGSARPPPPDSD----------SGSSDYCMLDCCEECHLSAFPGHTESPELTLAQP IL9R_MOUSE IL9R_MOUSE DWAPLGSARPPPPDSD----------SGSSDYCMLDCCEECHLSAFPGHTESPELTLAQP Q78PA5_MOUSE Q78PA5_MOUSE DWAPLGSARPPPPDSD----------SGSSDYCMLDCCEECHLSAFPGHTESPELTLAQP Q2M2M3_MOUSE Q2M2M3_MOUSE DWAPLGSARPPPPDSD----------SGSSDYCMLHCCEECHLSAFPGHTQSPELTLAQP Q8C2G1_MOUSE Q8C2G1_MOUSE DWAPLGSARPPPPDSD----------SGSSDYCMLDCCEECHLSAFPGHTQSPELTLAQP MATCH **** . :**.* **: *...:** * * .**.:* :* *. * . CONSENSUS DWAPLGSARPPPPDSD??????????SGSSDYCML?C?EE?HLSAFPGHT?SPE?TLAQP

IL9R_HUMAN IL9R_HUMAN CGLSCDHQGLETQQGVAWVLAGHCQRPGLHEDLQGMLLPSVLSKARSWTF Q63216_RAT Q63216_RAT VALAVSSRA----------------------------------------- B7ZD65_MOUSE B7ZD65_MOUSE VALPVSSRA----------------------------------------- A2AVE0_MOUSE A2AVE0_MOUSE VALPVSSRA----------------------------------------- IL9R_MOUSE IL9R_MOUSE VALPVSSRA----------------------------------------- Q78PA5_MOUSE Q78PA5_MOUSE VALPVSSRA----------------------------------------- Q2M2M3_MOUSE Q2M2M3_MOUSE VALPVSSRA----------------------------------------- Q8C2G1_MOUSE Q8C2G1_MOUSE VALPVSSRA----------------------------------------- MATCH .*. . :. CONSENSUS VAL?VSSRA?????????????????????????????????????????


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