Alignment of the gene Family HBG005554 of HOVERGEN

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Isoforms are ON
Q4RZ05_TETNG Q4RZ05_TETNG ------------------------------------------------------------ Q5XHE7_XENLA Q5XHE7_XENLA ------------------------------------------------------------ ECEL1_HUMAN ECEL1_HUMAN ------------------------------------------------------------ ECEL1_RAT ECEL1_RAT ------------------------------------------------------------ ECEL1_MOUSE ECEL1_MOUSE ------------------------------------------------------------ Q6PFG4_MOUSE Q6PFG4_MOUSE ------------------------------------------------------------ Q3TX93_MOUSE Q3TX93_MOUSE ------------------------------------------------------------ Q4SB05_TETNG Q4SB05_TETNG ------------------------------------------------------------ B4DKF3_HUMAN B4DKF3_HUMAN ------------------------------------------------------------ ECE2_BOVIN ECE2_BOVIN ACLGPSAQVPELPEKNCGYREVQYWDQRYQGAADSAPYEWFGDFSCFRDLLEPELRPLDR Q865C2_BOVIN Q865C2_BOVIN --------------------------------------------------------MRVA Q865C3_BOVIN Q865C3_BOVIN ------------------------------------------------------------ B4DF19_HUMAN B4DF19_HUMAN ------------------------------------------------------------ ECE2_HUMAN ECE2_HUMAN ASPGAGRAPPELPERNCGYREVEYWDQRYQGAADSAPYDWFGDFSSFRALLEPELRPEDR B4DHU4_HUMAN B4DHU4_HUMAN ------------------------------------------------------------ Q6UW36_HUMAN Q6UW36_HUMAN ------------------------------------------------------------ A5PLK8_HUMAN A5PLK8_HUMAN ------------------------------------------------------------ Q8NFD7_HUMAN Q8NFD7_HUMAN --------------------------------------------------------MNVA Q6IE65_RAT Q6IE65_RAT --------------------------------------------------------MNVA ECE2_MOUSE ECE2_MOUSE ASPRTPVSPPELPEKNFQYRQVQYWDQRYKDAADSGPYEWFGDFASFRALLEPELCPEDR Q80Z57_MOUSE Q80Z57_MOUSE --------------------------------------------------------MNVA Q80Z58_MOUSE Q80Z58_MOUSE ------------------------------------------------------------ Q8K0P0_MOUSE Q8K0P0_MOUSE ------------------------------------------------------------ Q8C099_MOUSE Q8C099_MOUSE --------------------------------------------------------MNVA B2RQR8_MOUSE B2RQR8_MOUSE --------------------------------------------------------MNVA Q923T6_MOUSE Q923T6_MOUSE --------------------------------------------------------MNVA Q4T614_TETNG Q4T614_TETNG ------------------------------------------------------------ A0JMP1_DANRE A0JMP1_DANRE ------------------------------------------------------------ A7LFV7_FUNHE A7LFV7_FUNHE ------------------------------------------------------------ Q32NT6_XENLA Q32NT6_XENLA ------------------------------------------------------------ B6RBR2_XENLA B6RBR2_XENLA ------------------------------------------------------------ Q7ZTK3_XENLA Q7ZTK3_XENLA ------------------------------------------------------------ Q9DGN6_CHICK Q9DGN6_CHICK ------------------------------------------------------------ ECE1_CAVPO ECE1_CAVPO ------------------------------------------------------------ Q2Z2K8_HUMAN Q2Z2K8_HUMAN ------------------------------------------------------------ B4DKB2_HUMAN B4DKB2_HUMAN ------------------------------------------------------------ ECE1_HUMAN ECE1_HUMAN ------------------------------------------------------------ ECE1_RAT ECE1_RAT ------------------------------------------------------------ ECE1_MOUSE ECE1_MOUSE ------------------------------------------------------------ Q6IN10_RAT Q6IN10_RAT ------------------------------------------------------------ Q3HTT4_CANFA Q3HTT4_CANFA ------------------------------------------------------------ ECE1_BOVIN ECE1_BOVIN ------------------------------------------------------------ Q28010_BOVIN Q28010_BOVIN ------------------------------------------------------------ Q28868_BOVIN Q28868_BOVIN ------------------------------------------------------------ O35812_RAT O35812_RAT ------------------------------------------------------------ A2ICR0_MOUSE A2ICR0_MOUSE ------------------------------------------------------------ Q3TYM9_MOUSE Q3TYM9_MOUSE ------------------------------------------------------------ PHEX_MOUSE PHEX_MOUSE ------------------------------------------------------------ A2AC80_MOUSE A2AC80_MOUSE ------------------------------------------------------------ B4E334_HUMAN B4E334_HUMAN ------------------------------------------------------------ B4DNS0_HUMAN B4DNS0_HUMAN ------------------------------------------------------------ B4DWG8_HUMAN B4DWG8_HUMAN ------------------------------------------------------------ PHEX_HUMAN PHEX_HUMAN ------------------------------------------------------------ A4QP66_DANRE A4QP66_DANRE ------------------------------------------------------------ Q4S1N5_TETNG Q4S1N5_TETNG ------------------------------------------------------------ B9DI79_HUMAN B9DI79_HUMAN ------------------------------------------------------------ MMEL1_HUMAN MMEL1_HUMAN ------------------------------------------------------------ B3KS82_HUMAN B3KS82_HUMAN ------------------------------------------------------------ MMEL1_RAT MMEL1_RAT ------------------------------------------------------------ B1AS15_MOUSE B1AS15_MOUSE ------------------------------------------------------------ B1AS16_MOUSE B1AS16_MOUSE ------------------------------------------------------------ B1AS17_MOUSE B1AS17_MOUSE ------------------------------------------------------------ B2RPX5_MOUSE B2RPX5_MOUSE ------------------------------------------------------------ MMEL1_MOUSE MMEL1_MOUSE ------------------------------------------------------------ Q4RX51_TETNG Q4RX51_TETNG ------------------------------------------------------------ B1WAX2_XENTR B1WAX2_XENTR ------------------------------------------------------------ Q67BJ2_CHICK Q67BJ2_CHICK ------------------------------------------------------------ NEP_RABIT NEP_RABIT ------------------------------------------------------------ NEP_PONAB NEP_PONAB ------------------------------------------------------------ B7ZKY6_HUMAN B7ZKY6_HUMAN ------------------------------------------------------------ NEP_HUMAN NEP_HUMAN ------------------------------------------------------------ NEP_MOUSE NEP_MOUSE ------------------------------------------------------------ NEP_RAT NEP_RAT ------------------------------------------------------------ O93394_PERFV O93394_PERFV ------------------------------------------------------------ Q4SPQ9_TETNG Q4SPQ9_TETNG ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

Q4RZ05_TETNG Q4RZ05_TETNG ------------------------------------------------------------ Q5XHE7_XENLA Q5XHE7_XENLA ------------------------------------------------------------ ECEL1_HUMAN ECEL1_HUMAN ------------------------------------------------------------ ECEL1_RAT ECEL1_RAT ------------------------------------------------------------ ECEL1_MOUSE ECEL1_MOUSE ------------------------------------------------------------ Q6PFG4_MOUSE Q6PFG4_MOUSE ------------------------------------------------------------ Q3TX93_MOUSE Q3TX93_MOUSE ------------------------------------------------------------ Q4SB05_TETNG Q4SB05_TETNG ------------------------------------------------------------ B4DKF3_HUMAN B4DKF3_HUMAN ------------------------------------------------------------ ECE2_BOVIN ECE2_BOVIN ILVLGCGNSALSYELFLGGFPDVTSVDYSSVVVAAMRARYAHVPTLRWETMDVRALGFPS Q865C2_BOVIN Q865C2_BOVIN LQELGGGGNMVEYK---------------------------------------------- Q865C3_BOVIN Q865C3_BOVIN ------------------------------------------------------------ B4DF19_HUMAN B4DF19_HUMAN ------------------------------------------------------------ ECE2_HUMAN ECE2_HUMAN ILVLGCGNSALSYELFLGGFPNVTSVDYSSVVVAAMQARHAHVPQLRWETMDVRKLDFPS B4DHU4_HUMAN B4DHU4_HUMAN ------------------------------------------------------------ Q6UW36_HUMAN Q6UW36_HUMAN ------------------------------------------------------------ A5PLK8_HUMAN A5PLK8_HUMAN ------------------------------------------------------------ Q8NFD7_HUMAN Q8NFD7_HUMAN LQELGAGSNMVEYK-----------------RATLRDEDAPETPVEGGASPDAMEVGKGA Q6IE65_RAT Q6IE65_RAT LQELGSGGSMVEYK---------------------------------------------- ECE2_MOUSE ECE2_MOUSE ILVLGCGNSALSYELFLGGFPNVTSVDYSPVVVAAMQVRYAHVPSLRWETMDVRALDFPS Q80Z57_MOUSE Q80Z57_MOUSE LHELGGGGSMVEYK---------------------------------------------- Q80Z58_MOUSE Q80Z58_MOUSE ------------------------------------------------------------ Q8K0P0_MOUSE Q8K0P0_MOUSE ------------------------------------------------------------ Q8C099_MOUSE Q8C099_MOUSE LHELGGGGSMVEYK---------------------------------------------- B2RQR8_MOUSE B2RQR8_MOUSE LHELGGGGSMVEYK---------------------------------------------- Q923T6_MOUSE Q923T6_MOUSE LHELGGGGSMVEYK---------------------------------------------- Q4T614_TETNG Q4T614_TETNG ----------------------------------------------------------ME A0JMP1_DANRE A0JMP1_DANRE ------------------------------------------------------------ A7LFV7_FUNHE A7LFV7_FUNHE ------------------------------------------------------------ Q32NT6_XENLA Q32NT6_XENLA ------------------------------------------------------------ B6RBR2_XENLA B6RBR2_XENLA ------------------------------------------------------------ Q7ZTK3_XENLA Q7ZTK3_XENLA ------------------------------------------------------------ Q9DGN6_CHICK Q9DGN6_CHICK ------------------------------------------------------------ ECE1_CAVPO ECE1_CAVPO ------------------------------------------------------------ Q2Z2K8_HUMAN Q2Z2K8_HUMAN ------------------------------------------------------------ B4DKB2_HUMAN B4DKB2_HUMAN -------------------------------------------------------MRGVW ECE1_HUMAN ECE1_HUMAN -------------------------------------------------------MRGVW ECE1_RAT ECE1_RAT ------------------------------------------------------------ ECE1_MOUSE ECE1_MOUSE --------------------------------------------------------MRTV Q6IN10_RAT Q6IN10_RAT ------------------------------------------------------------ Q3HTT4_CANFA Q3HTT4_CANFA ------------------------------------------------------------ ECE1_BOVIN ECE1_BOVIN ------------------------------------------------------------ Q28010_BOVIN Q28010_BOVIN ------------------------------------------------------------ Q28868_BOVIN Q28868_BOVIN ------------------------------------------------------------ O35812_RAT O35812_RAT ------------------------------------------------------------ A2ICR0_MOUSE A2ICR0_MOUSE ------------------------------------------------------------ Q3TYM9_MOUSE Q3TYM9_MOUSE ------------------------------------------------------------ PHEX_MOUSE PHEX_MOUSE ------------------------------------------------------------ A2AC80_MOUSE A2AC80_MOUSE ------------------------------------------------------------ B4E334_HUMAN B4E334_HUMAN ------------------------------------------------------------ B4DNS0_HUMAN B4DNS0_HUMAN ------------------------------------------------------------ B4DWG8_HUMAN B4DWG8_HUMAN ------------------------------------------------------------ PHEX_HUMAN PHEX_HUMAN ------------------------------------------------------------ A4QP66_DANRE A4QP66_DANRE ------------------------------------------------------------ Q4S1N5_TETNG Q4S1N5_TETNG ------------------------------------------------------------ B9DI79_HUMAN B9DI79_HUMAN ------------------------------------------------------------ MMEL1_HUMAN MMEL1_HUMAN ------------------------------------------------------------ B3KS82_HUMAN B3KS82_HUMAN ------------------------------------------------------------ MMEL1_RAT MMEL1_RAT ------------------------------------------------------------ B1AS15_MOUSE B1AS15_MOUSE ------------------------------------------------------------ B1AS16_MOUSE B1AS16_MOUSE ------------------------------------------------------------ B1AS17_MOUSE B1AS17_MOUSE ------------------------------------------------------------ B2RPX5_MOUSE B2RPX5_MOUSE ------------------------------------------------------------ MMEL1_MOUSE MMEL1_MOUSE ------------------------------------------------------------ Q4RX51_TETNG Q4RX51_TETNG ------------------------------------------------------------ B1WAX2_XENTR B1WAX2_XENTR ------------------------------------------------------------ Q67BJ2_CHICK Q67BJ2_CHICK ------------------------------------------------------------ NEP_RABIT NEP_RABIT ------------------------------------------------------------ NEP_PONAB NEP_PONAB ------------------------------------------------------------ B7ZKY6_HUMAN B7ZKY6_HUMAN ------------------------------------------------------------ NEP_HUMAN NEP_HUMAN ------------------------------------------------------------ NEP_MOUSE NEP_MOUSE ------------------------------------------------------------ NEP_RAT NEP_RAT ------------------------------------------------------------ O93394_PERFV O93394_PERFV ------------------------------------------------------------ Q4SPQ9_TETNG Q4SPQ9_TETNG ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

Q4RZ05_TETNG Q4RZ05_TETNG -----MEKTYSLTAHYDEFQEVKYGGRYSSDILSNGMTLHLGGSLDRHMGRSRGGTWSNK Q5XHE7_XENLA Q5XHE7_XENLA -----MEKTYSLTAHYD-------------EFQEVKYVSKYNSCSTLS-NGFNLQVSSKK ECEL1_HUMAN ECEL1_HUMAN -------MEPPYSLTAH-------------YDEFQEVKYVSRCGAGGA-RGASLPPGFPL ECEL1_RAT ECEL1_RAT ---------------------MEAPYSMTAHYDEFQEVKYESRCGTGGARGTSLPPGFPR ECEL1_MOUSE ECEL1_MOUSE ---------------------MEAPYSMTAHYDEFQEVKYVSRCGTGGARGTSLPPGFPR Q6PFG4_MOUSE Q6PFG4_MOUSE ---------------------MEAPYSMTAHYDEFQEVKYVSRCGTGGARGTSLPPGFPR Q3TX93_MOUSE Q3TX93_MOUSE ---------------------MEAPYSMTAHYDEFQEVKYVSRCGTGGARGTSLPPGFPR Q4SB05_TETNG Q4SB05_TETNG ------------------------------------------------------QVGFRK B4DKF3_HUMAN B4DKF3_HUMAN -----------------------------------------MNVALQE-LGAGSNVGFQK ECE2_BOVIN ECE2_BOVIN GSFDVVLEKGTLDALLT-------------GEQDPWTVSSEG--VHTV-DQVLNEAGFRK Q865C2_BOVIN Q865C2_BOVIN ------------------------------RATLRDEDAPETPVEGGA-SPDAVEAGFRK Q865C3_BOVIN Q865C3_BOVIN -----------------------------------------MRVALQE-LGGGGNAGFRK B4DF19_HUMAN B4DF19_HUMAN ----------MTPGTPR-------------SSGLFWRVTCPHLRSISG-LCSRTMVGFQK ECE2_HUMAN ECE2_HUMAN ASFDVVLEKGTLDALLA-------------GERDPWTVSSEG--VHTV-DQVLSEVGFQK B4DHU4_HUMAN B4DHU4_HUMAN ------------------------------------------------------------ Q6UW36_HUMAN Q6UW36_HUMAN -----------------------------------------MNVALQE-LGAGSNVGFQK A5PLK8_HUMAN A5PLK8_HUMAN -----------------------------------------MNVALQE-LGAGSNVGFQK Q8NFD7_HUMAN Q8NFD7_HUMAN SPFSPGPSPGMTPGTPR-------------SSGLFWRVTCPHLRSISG-LCSRTMVGFQK Q6IE65_RAT Q6IE65_RAT ------------RAKLQ-------------DEELPE-----VTVEGRA-IQDSLEVGSQK ECE2_MOUSE ECE2_MOUSE GSFDVVLEKGTLDAMLA-------------GEPDPWNVSSEG--VHTV-DQVLSEVGFQK Q80Z57_MOUSE Q80Z57_MOUSE ------------RAKLR-------------DEESPE-----ITVEGRA-TRDSLEVGFQK Q80Z58_MOUSE Q80Z58_MOUSE -----------------------------------------MNVALHE-LGGGGSVGFQK Q8K0P0_MOUSE Q8K0P0_MOUSE ------------------------------------------------------------ Q8C099_MOUSE Q8C099_MOUSE ------------RAKLR-------------DEESPE-----ITVEGRA-TRDSLEVGFQK B2RQR8_MOUSE B2RQR8_MOUSE ------------RAKLR-------------DEESPE-----ITVEGRA-TRDSLEVGFQK Q923T6_MOUSE Q923T6_MOUSE ------------RAKLR-------------DEESPE-----ITVEGRA-TRDSLEVGFQK Q4T614_TETNG Q4T614_TETNG ALRDSVLNLTFQMSPYK-------------RATLDEEELVEATPDDSY-PSSSMQVTFLH A0JMP1_DANRE A0JMP1_DANRE ------------MSTYK-------------RATLEEEELLDTGSDGIY-HTSSMQVGVQR A7LFV7_FUNHE A7LFV7_FUNHE ------------------------------------------------------------ Q32NT6_XENLA Q32NT6_XENLA -----------MEALRESVGHFSFQMSAYKRATLDEEDLVDSLGEGEV-YPNGLQVNLRG B6RBR2_XENLA B6RBR2_XENLA ------------MSAYK-------------RATLDEEDLVDSLGEGEV-YPNGLQVNLRG Q7ZTK3_XENLA Q7ZTK3_XENLA ------------MSAYK-------------RATLDEEDLVDSLGEGEV-YPNGLQVNLRG Q9DGN6_CHICK Q9DGN6_CHICK ------------MSTYK-------------RATLDDEDPLDSISESDG-YPNGFQVNFSR ECE1_CAVPO ECE1_CAVPO -----------MMSTYK-------------RATLDEEDLVDSLSEGEV-YPNGLQVNFRN Q2Z2K8_HUMAN Q2Z2K8_HUMAN -----------MMSTYK-------------RATLDEEDLVDSLSEGDA-YPNGLQVNFHS B4DKB2_HUMAN B4DKB2_HUMAN PPPVSALLSALGMSTYK-------------RATLDEEDLVDSLSEGDA-YPNGLQVNFHS ECE1_HUMAN ECE1_HUMAN PPPVSALLSALGMSTYK-------------RATLDEEDLVDSLSEGDA-YPNGLQVNFHS ECE1_RAT ECE1_RAT -----------------MGSLRPPQGLGLQWSSFFLGKKGPGLTVSLPLLASSLQVNFRS ECE1_MOUSE ECE1_MOUSE WSPLAAALAALGMSTYK-------------RATLDEEDLVDSLSEGDV-YPNGLQVNFRS Q6IN10_RAT Q6IN10_RAT -----------MMSSYK-------------RATLDEEDLVDSLSEGDV-YPNGLQVNFRS Q3HTT4_CANFA Q3HTT4_CANFA --------------------------------------LVDSLSEGEV-YPNGLQVNFRS ECE1_BOVIN ECE1_BOVIN -----------MMSTYK-------------RATLDEEDLVDSLSESDV-YPNHLQVNFRG Q28010_BOVIN Q28010_BOVIN ---------------------MSPRGQDLLRSPLLLGSEAPGLTSSPFRLPPSLQVNFRG Q28868_BOVIN Q28868_BOVIN ---------------------MSPRGQDLLRSPLLLGSEAPGLTSSPFRLPPSLQVNFRG O35812_RAT O35812_RAT -------------------------------------------------MEAEAGSTMET A2ICR0_MOUSE A2ICR0_MOUSE -------------------------------------------------MEAETGSTMET Q3TYM9_MOUSE Q3TYM9_MOUSE -------------------------------------------------MEAETGSTMET PHEX_MOUSE PHEX_MOUSE -------------------------------------------------MEAETGSTMET A2AC80_MOUSE A2AC80_MOUSE -------------------------------------------------MEAETGSTMET B4E334_HUMAN B4E334_HUMAN ------------------------------------------------------------ B4DNS0_HUMAN B4DNS0_HUMAN -------------------------------------------------MEAETGSSVET B4DWG8_HUMAN B4DWG8_HUMAN ------------------------------------------------------------ PHEX_HUMAN PHEX_HUMAN -------------------------------------------------MEAETGSSVET A4QP66_DANRE A4QP66_DANRE ------------------------------------------------------------ Q4S1N5_TETNG Q4S1N5_TETNG ------------------------------------------------------------ B9DI79_HUMAN B9DI79_HUMAN -----------------------------------------------M-GKSEGPVGMVE MMEL1_HUMAN MMEL1_HUMAN -----------------------------------------------M-GKSEGPVGMVE B3KS82_HUMAN B3KS82_HUMAN -----------------------------------------------M-GKSEGPVGMVE MMEL1_RAT MMEL1_RAT -----------------------------------------------M-GKSESSVGMME B1AS15_MOUSE B1AS15_MOUSE -----------------------------------------------------------M B1AS16_MOUSE B1AS16_MOUSE -----------------------------------------------------------M B1AS17_MOUSE B1AS17_MOUSE -----------------------------------------------------------M B2RPX5_MOUSE B2RPX5_MOUSE -----------------------------------------------------------M MMEL1_MOUSE MMEL1_MOUSE -----------------------------------------------------------M Q4RX51_TETNG Q4RX51_TETNG ---------------------------------------------GKS-ESQMDIMEKSN B1WAX2_XENTR B1WAX2_XENTR --------------------------------------------MGKS-ESQMDIVEKST Q67BJ2_CHICK Q67BJ2_CHICK --------------------------------------------MGKS-ESQMDITEMNA NEP_RABIT NEP_RABIT --------------------------------------------MGRS-ESQMDITDINT NEP_PONAB NEP_PONAB --------------------------------------------MGKS-ESQMDITDINT B7ZKY6_HUMAN B7ZKY6_HUMAN --------------------------------------------MGKS-ESQMDITDINT NEP_HUMAN NEP_HUMAN --------------------------------------------MGKS-ESQMDITDINT NEP_MOUSE NEP_MOUSE --------------------------------------------MGRS-ESQMDITDINA NEP_RAT NEP_RAT --------------------------------------------MGRS-ESQMDITDINA O93394_PERFV O93394_PERFV ------------MPIYI-------------IDRKFPDTSGELIQPAAE-AGDLRMMETNP Q4SPQ9_TETNG Q4SPQ9_TETNG ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

Q4RZ05_TETNG Q4RZ05_TETNG NKDLSGASSSKGVPRWSRREICLLSALVFAAGLCVILGSMLTLKYISLDSQQDPQC---- Q5XHE7_XENLA Q5XHE7_XENLA QT-------KKGVPRWSRRETCLLSGLVFAVGLCVILGCMLVLKYLSMEQDGQC------ ECEL1_HUMAN ECEL1_HUMAN GAARSATGARSGLPRWNRREVCLLSGLVFAAGLCAILAAMLALKYLGPVAAGGGAC---- ECEL1_RAT ECEL1_RAT SSGRSASGARSGLPRWNRREVCLLSGLVFAAGLCAILAAMLALKYLGPGAAGTGGAC--- ECEL1_MOUSE ECEL1_MOUSE GSGRSASGSRSGLPRWNRREVCLLSGLVFAAGLCAILAAMLALKYLGPGAAGGGGAC--- Q6PFG4_MOUSE Q6PFG4_MOUSE GSGRSASGSRSGLPRWNRREVCLLSGLVFAAGLCAILAAMLALKYLGPGAAGGGGAC--- Q3TX93_MOUSE Q3TX93_MOUSE GSGRSASGSRSGLPRWNRREVCLLSGLVFAAGLCAILAAMLALKYLGPGAAGGGGAC--- Q4SB05_TETNG Q4SB05_TETNG GG-------VDVLGRRTRLEVLLL--VLLLVTLLALLACLLVLGLGFHSDHG-------- B4DKF3_HUMAN B4DKF3_HUMAN GT-------RQLLGSRTQLELVLA--GASLLLAALLLGCLVALGVQYHRDPS-------- ECE2_BOVIN ECE2_BOVIN RT-------SRLLGLHTQLELVLA--GVSLLLAALLLGCLVALGVQYHRDPS-------- Q865C2_BOVIN Q865C2_BOVIN RT-------SRLLGLHTQLELVLA--GVSLLLAALLLGCLVALGVQYHRDPS-------- Q865C3_BOVIN Q865C3_BOVIN RT-------SRLLGLHTQLELVLA--GVSLLLAALLLGCLVALGVQYHRDPS-------- B4DF19_HUMAN B4DF19_HUMAN GT-------RQLLGSRTQLELVLA--GASLLLAALLLGCLVALGVQYHRDPS-------- ECE2_HUMAN ECE2_HUMAN GT-------RQLLGSRTQLELVLA--GASLLLAALLLGCLVALGVQYHRDPS-------- B4DHU4_HUMAN B4DHU4_HUMAN ------------------------------------------------------------ Q6UW36_HUMAN Q6UW36_HUMAN GT-------RQLLGSRTQLELVLA--GASLLLAALLLGCLVALGVQYHRDPS-------- A5PLK8_HUMAN A5PLK8_HUMAN GT-------RQLLGSRTQLELVLA--GASLLLAALLLGCLVALGVQYHRDPS-------- Q8NFD7_HUMAN Q8NFD7_HUMAN GT-------RQLLGSRTQLELVLA--GASLLLAALLLGCLVALGVQYHRDPS-------- Q6IE65_RAT Q6IE65_RAT RT-------RQLFGSHTQLELVLA--GLILVLAALLLGCLVALWV--HTDPV-------- ECE2_MOUSE ECE2_MOUSE RT-------RQLFGSHTQLELVLA--GLILVLAALLLGCLVALWV--HRDPA-------- Q80Z57_MOUSE Q80Z57_MOUSE RT-------RQLFGSHTQLELVLA--GLILVLAALLLGCLVALWV--HRDPA-------- Q80Z58_MOUSE Q80Z58_MOUSE RT-------RQLFGSHTQLELVLA--GLILVLAALLLGCLVALWV--HRDPA-------- Q8K0P0_MOUSE Q8K0P0_MOUSE ------------------------------------------------------------ Q8C099_MOUSE Q8C099_MOUSE RT-------RQLFGSHTQLELVLA--GLILVLAALLLGCLVALWV--HRDPA-------- B2RQR8_MOUSE B2RQR8_MOUSE RT-------RQLFGSHTQLELVLA--GLILVLAALLLGCLVALWV--HRDPA-------- Q923T6_MOUSE Q923T6_MOUSE RT-------RQLFGSHTQLELVLA--GLILVLAALLLGCLVALWV--HRDPA-------- Q4T614_TETNG Q4T614_TETNG GRR------PTCCPSWTQRERRLL--LVLGAAAAALLVSLLAGGVFYRQGH--------- A0JMP1_DANRE A0JMP1_DANRE GLG------LRCWAEKNHSERKLV--VLVCALSVALFICIVSLGLHYKESH--------- A7LFV7_FUNHE A7LFV7_FUNHE ------------------------------------------------------------ Q32NT6_XENLA Q32NT6_XENLA VGRR-----SGCWSERTHVEKRLL--VLLVLMSLGLFMSLLALSLQYRNS---------- B6RBR2_XENLA B6RBR2_XENLA VGRW-----SGCWSERTHVEKRLL--VLLVLMSLGLFMSLLALSLQYRNS---------- Q7ZTK3_XENLA Q7ZTK3_XENLA VGRR-----SGCWSERTHVEKRLL--VLLVLMSLGLFMSLLALSLQYRNS---------- Q9DGN6_CHICK Q9DGN6_CHICK SS-------VGCWAQRTRPEKQLV--AVVAVLAAVLGACLLGLVLQYRARP--------- ECE1_CAVPO ECE1_CAVPO FRSS-----QRCWATRTQVEKRLI--VLVALLAAGLVACLTALGIQYRTRT--------- Q2Z2K8_HUMAN Q2Z2K8_HUMAN PRSG-----QRCWAARTQVEKRLV--VLVVLLAAGLVACLAALGIQYQTRS--------- B4DKB2_HUMAN B4DKB2_HUMAN PRSG-----QRCWAARTQVEKRLV--VLVVLLAAGLVACLAALGIQYQTRS--------- ECE1_HUMAN ECE1_HUMAN PRSG-----QRCWAARTQVEKRLV--VLVVLLAAGLVACLAALGIQYQTRS--------- ECE1_RAT ECE1_RAT PRSG-----QRCWAARTSVEKRLV--VLVTLLAAGLVACLAALGIQYRTRT--------- ECE1_MOUSE ECE1_MOUSE SRSG-----QRCWAARTSVEKRLV--VLVTLLAAGLVACLAALGIQYQTRT--------- Q6IN10_RAT Q6IN10_RAT PRSG-----QRCWAARTSVEKRLV--VLVTLLAAGLVACLAALGIQYRTRT--------- Q3HTT4_CANFA Q3HTT4_CANFA PRSG-----QRCWAARTPVEKRLV--VLVALLAAGLVACLAALGVQYRTRT--------- ECE1_BOVIN ECE1_BOVIN PRNG-----QRCWAARTPVEKRLV--VLVALLAAALVACLAVLGIQYQTRT--------- Q28010_BOVIN Q28010_BOVIN PRNG-----QRCWAARTPVEKRLV--VLVALLAAALVACLAVLGIQYQTRT--------- Q28868_BOVIN Q28868_BOVIN PRNG-----QRCWAARTPVEKRLV--VLVALLAAALVACLAVLGIQYQTRT--------- O35812_RAT O35812_RAT GK-------GTNRGIRIALALFIT--GTLVLGTLLFLVSQGLLSFQAK------------ A2ICR0_MOUSE A2ICR0_MOUSE GK-------GTNRGIRIALALFIG--GTLVLGTLLFLVSQGLLSFQAK------------ Q3TYM9_MOUSE Q3TYM9_MOUSE GK-------GTNRGIRIALALFIG--GTLVLGTLLFLVSQGLLSFQAK------------ PHEX_MOUSE PHEX_MOUSE GK-------GTNRGIRIALALFIG--GTLVLGTLLFLVSQGLLSFQAK------------ A2AC80_MOUSE A2AC80_MOUSE GK-------GTNRGIRIALALFIG--GTLVLGTLLFLVSQGLLSFQAK------------ B4E334_HUMAN B4E334_HUMAN ------------------------------------------------------------ B4DNS0_HUMAN B4DNS0_HUMAN GK-------KANRGTRIALVVFVG--GTLVLGTILFLVSQGLLSLQAK------------ B4DWG8_HUMAN B4DWG8_HUMAN ------------------------------------------------------------ PHEX_HUMAN PHEX_HUMAN GK-------KANRGTRIALVVFVG--GTLVLGTILFLVSQGLLSLQAK------------ A4QP66_DANRE A4QP66_DANRE ------------------------------------------------------------ Q4S1N5_TETNG Q4S1N5_TETNG Q----------------------------------------------------------- B9DI79_HUMAN B9DI79_HUMAN ---------SAGRAGQKRPGFLEG--GLLL-LLLLVTAALVALGVLYADRRGKQLPRLAS MMEL1_HUMAN MMEL1_HUMAN ---------SAGRAGQKRPGFLEG--GLLL-LLLLVTAALVALGVLYADRRGKQLPRLAS B3KS82_HUMAN B3KS82_HUMAN ---------SAGRAGQKRPGFLEG--GLLL-LLLLVTAALVALGVLYADRRGKQLPRLAS MMEL1_RAT MMEL1_RAT RA-------D--NCGRRRLGFVEC--GLLVLLTLLLMGAIVTLGVFYSIGKQLPLLNSLL B1AS15_MOUSE B1AS15_MOUSE VE-------RAGWCRKKSPGFVEY--GLMVLLLLLLLGAIVTLGVFYSIGKQLPLLTSLL B1AS16_MOUSE B1AS16_MOUSE VE-------RAGWCRKKSPGFVEY--GLMVLLLLLLLGAIVTLGVFYSIALRDSSLK--- B1AS17_MOUSE B1AS17_MOUSE VE-------RAGWCRKKSPGFVEY--GLMVLLLLLLLGAIVTLGVFYSIALRDSSLK--- B2RPX5_MOUSE B2RPX5_MOUSE VE-------RAGWCRKKSPGFVEY--GLMVLLL-LLLGAIVTLGVFYSIALRDSSLK--- MMEL1_MOUSE MMEL1_MOUSE VE-------RAGWCRKKSPGFVEY--GLMVLLL-LLLGAIVTLGVFYSIGKQLPLLTSLL Q4RX51_TETNG Q4RX51_TETNG ---------KPGKHRWTATEIGL---FVLLLLVSCALAGLVVLYTSVTKERSNTSSGLRC B1WAX2_XENTR B1WAX2_XENTR ---------KSAKKSWSFVEIGL---SVLLFLMTCAVVALLVLYTSHK------------ Q67BJ2_CHICK Q67BJ2_CHICK PK-------PKKKLRWSGLEIGL---TVVVILLAIVAITMIVLYATYD------------ NEP_RABIT NEP_RABIT PK-------PKKKQRWTPLEISL---SVLVLLLTVIAVTMIALYATYD------------ NEP_PONAB NEP_PONAB PK-------PKKKQRWTPLEISL---SVLVLLLTIIAVTMIALYATYD------------ B7ZKY6_HUMAN B7ZKY6_HUMAN PK-------PKKKQRWTPLEISL---SVLVLLLTIIAVTMIALYATYD------------ NEP_HUMAN NEP_HUMAN PK-------PKKKQRWTPLEISL---SVLVLLLTIIAVTMIALYATYD------------ NEP_MOUSE NEP_MOUSE PK-------PKKKQRWTPLEISL---SVLVLLLTIIAVTMIALYATYD------------ NEP_RAT NEP_RAT PK-------PKKKQRWTPLEISL---SVLVLLLTIIAVTMIALYATYD------------ O93394_PERFV O93394_PERFV PK-------SAKKPRWTSLEVGLT--TIVSLLFIVIVALIILFATQKT------------ Q4SPQ9_TETNG Q4SPQ9_TETNG ------------------------------------------------------------ MATCH CONSENSUS ??????????????????????????????????????????L?????????????????

Q4RZ05_TETNG Q4RZ05_TETNG -------------------------RQDCQRKRTLLRAARFIQANIDPTIQPCQDFYSFA Q5XHE7_XENLA Q5XHE7_XENLA -------------------------LEGCQERKAFTRASKFITNNIDPTISPCTDFYSFA ECEL1_HUMAN ECEL1_HUMAN -------------------------PEGCPERKAFARAARFLAANLDASIDPCQDFYSFA ECEL1_RAT ECEL1_RAT -------------------------PEGCPERKAFARAARFLSANLDASIDPCQDFYSFA ECEL1_MOUSE ECEL1_MOUSE -------------------------PEGCPERKAFARAARFLSANLDASIDPCQDFYSFA Q6PFG4_MOUSE Q6PFG4_MOUSE -------------------------PEGCPERKAFARAARFLSANLDASIDPCQDFYSFA Q3TX93_MOUSE Q3TX93_MOUSE -------------------------PEGCPERKAFARAARFLSANLDASIDPCQDFYSFA Q4SB05_TETNG Q4SB05_TETNG -------------------------HGFCLSEACVTVASQMVE-AMDRSADPCHDFYQFA B4DKF3_HUMAN B4DKF3_HUMAN -------------------------HSTCLTEACIRVAGKILE-SLDRGVSPCEDFYQFS ECE2_BOVIN ECE2_BOVIN -------------------------HSTCLTEACIRVAGKILE-SLDRGVSPCEDFYQFS Q865C2_BOVIN Q865C2_BOVIN -------------------------HSTCLTEACIRVAGKILE-SLDRGVSPCEDFYQFS Q865C3_BOVIN Q865C3_BOVIN -------------------------HSTCLTEACIRVAGKILE-SLDRGVSPCEDFYQFS B4DF19_HUMAN B4DF19_HUMAN -------------------------HSTCLTEACIRVAGKILE-SLDRGVSPCEDFYQFS ECE2_HUMAN ECE2_HUMAN -------------------------HSTCLTEACIRVAGKILE-SLDRGVSPCEDFYQFS B4DHU4_HUMAN B4DHU4_HUMAN ------------------------------------------------------------ Q6UW36_HUMAN Q6UW36_HUMAN -------------------------HSTCLTEACIRVAGKILE-SLDRGVSPCEDFYQFS A5PLK8_HUMAN A5PLK8_HUMAN -------------------------HSTCLTEACIRVAGKILE-SLDRGVSPCEDFYQFS Q8NFD7_HUMAN Q8NFD7_HUMAN -------------------------HSTCLTEACIRVAGKILE-SLDRGVSPCEDFYQFS Q6IE65_RAT Q6IE65_RAT -------------------------HSTCITEACIRVAGKILE-SLDRGVSPCQDFYQFS ECE2_MOUSE ECE2_MOUSE -------------------------HSTCVTEACIRVAGKILE-SLDRGVSPCQDFYQFS Q80Z57_MOUSE Q80Z57_MOUSE -------------------------HSTCVTEACIRVAGKILE-SLDRGVSPCQDFYQFS Q80Z58_MOUSE Q80Z58_MOUSE -------------------------HSTCVTEACIRVAGKILE-SLDRGVSPCQDFYQFS Q8K0P0_MOUSE Q8K0P0_MOUSE ------------------------------------------------------------ Q8C099_MOUSE Q8C099_MOUSE -------------------------HSTCVTEACIRVAGKILE-SLDRGVSPCQDFYQFS B2RQR8_MOUSE B2RQR8_MOUSE -------------------------HSTCVTEACIRVAGKILE-SLDRGVSPCQDFYQFS Q923T6_MOUSE Q923T6_MOUSE -------------------------HSTCVTEACIRVAGKILE-SLDRGVSPCQDFYQFS Q4T614_TETNG Q4T614_TETNG -------------------------PGLCLSEPCVAVASAVLG-GLDRSVDPCSDFYQYA A0JMP1_DANRE A0JMP1_DANRE -------------------------PGLCLSEPCVSVASAVLG-SLDRSVDPCQDFYNFA A7LFV7_FUNHE A7LFV7_FUNHE ------------------------------------------------------------ Q32NT6_XENLA Q32NT6_XENLA -------------------------NRVCLSESCISITSSILR-SLDRSVDPCQDFYQYS B6RBR2_XENLA B6RBR2_XENLA -------------------------NRVCLSESCISVTSSILR-SLDRSVDPCQDFYQYS Q7ZTK3_XENLA Q7ZTK3_XENLA -------------------------NRVCLSESCISVTSSILR-SLDRSVDPCQDFYQYS Q9DGN6_CHICK Q9DGN6_CHICK -------------------------PAVCLSEACISVTSSILS-SLDRTVNPCEDFFSYA ECE1_CAVPO ECE1_CAVPO -------------------------PPVCLSEACVSVTSSILN-SMNPTVDPCQDFFSYA Q2Z2K8_HUMAN Q2Z2K8_HUMAN -------------------------PSVCLSEACVSVTSSILS-SMDPTVDPCHDFFSYA B4DKB2_HUMAN B4DKB2_HUMAN -------------------------PSVCLSEACVSVTSSILS-SMDPTVDPCHDFFSYA ECE1_HUMAN ECE1_HUMAN -------------------------PSVCLSEACVSVTSSILS-SMDPTVDPCHDFFSYA ECE1_RAT ECE1_RAT -------------------------PPVCLTEACVSVTSSILN-SMDPTVDPCQDFFSYA ECE1_MOUSE ECE1_MOUSE -------------------------PPVCLTEACVSVTSSILN-SMDPTVDPCQDFFSYA Q6IN10_RAT Q6IN10_RAT -------------------------PPVCLTEACVSVTSSILN-SMDPTVDPCQDFFSYA Q3HTT4_CANFA Q3HTT4_CANFA -------------------------PPVCLSEACISVTSSILS-SMDPTVDPCQDFFTYA ECE1_BOVIN ECE1_BOVIN -------------------------PSVCLSEACISVTSSILS-SMDPTVDPCQDFFTYA Q28010_BOVIN Q28010_BOVIN -------------------------PSVCLSEGCISVTSSILS-SMDPTVDPCQDFFTYA Q28868_BOVIN Q28868_BOVIN -------------------------PSVCLSEACISVTSSILS-SMDPTVDPCQDFFTYA O35812_RAT O35812_RAT -------------------------QEYCLKPECIEAAAAIMS-KVNLSVDPCENFFRFA A2ICR0_MOUSE A2ICR0_MOUSE -------------------------QEYCLKPECIEAAAAIMS-KVNLSVDPCENSFRFA Q3TYM9_MOUSE Q3TYM9_MOUSE -------------------------QEYCLKPECIEAAAAIMS-KVNLSVDPCENFFRFA PHEX_MOUSE PHEX_MOUSE -------------------------QEYCLKPECIEAAAAIMS-KVNLSVDPCENFFRFA A2AC80_MOUSE A2AC80_MOUSE -------------------------QEYCLKPECIEAAAAIMS-KVNLSVDPCENFFRFA B4E334_HUMAN B4E334_HUMAN ------------------------------------------------------------ B4DNS0_HUMAN B4DNS0_HUMAN -------------------------QEYCLKPECIEAAAAILS-KVNLSVDPCDNFFRFA B4DWG8_HUMAN B4DWG8_HUMAN ------------------------------------------------------------ PHEX_HUMAN PHEX_HUMAN -------------------------QEYCLKPECIEAAAAILS-KVNLSVDPCDNFFRFA A4QP66_DANRE A4QP66_DANRE ------------------------------------------------------------ Q4S1N5_TETNG Q4S1N5_TETNG -------------------------EEFCLSPECIEAAGSILS-KIDPSVNPCDDFYTFA B9DI79_HUMAN B9DI79_HUMAN RLCFLQEERTFVKRKPRGIPEAQEVSEVCTTPGCVIAAARILQ-NMDPTTEPCDDFYQFA MMEL1_HUMAN MMEL1_HUMAN RLCFLQEERTFVKRKPRGIPEAQEVSEVCTTPGCVIAAARILQ-NMDPTTEPCDDFYQFA B3KS82_HUMAN B3KS82_HUMAN RLCFLQEERTFVKRKPRGIPEAQEESEACTTPGCVIAAARILQ-NMDPTTEPCDDFYQFA MMEL1_RAT MMEL1_RAT HVSRHERTVVKRVLRDSSQK-----SDICTTPSCVIAAARILQ-NMDQSKKPCDNFYQYA B1AS15_MOUSE B1AS15_MOUSE HFSWDERTVVKRALRDSSLK-----SDICTTPSCVIAAARILE-NMDQSRNPCENFYQYA B1AS16_MOUSE B1AS16_MOUSE -------------------------SDICTTPSCVIAAARILE-NMDQSRNPCENFYQYA B1AS17_MOUSE B1AS17_MOUSE -------------------------SDICTTPSCVIAAARILE-NMDQSRNPCENFYQYA B2RPX5_MOUSE B2RPX5_MOUSE -------------------------SDICTTPSCVIAAARILE-NMDQSRNPCENFYQYA MMEL1_MOUSE MMEL1_MOUSE HFSWDERTVVKRALRDSSLK-----SDICTTPSCVIAAARILE-NMDQSRNPCENFYQYA Q4RX51_TETNG Q4RX51_TETNG TAGQLFHSSL---------------DPVCTTADCVTAAARLLQ-NMDTSVKPCDNFYQYA B1WAX2_XENTR B1WAX2_XENTR -------------------------ESICTTTGCVTAAARIIQ-NMDPTIEPCTDFYQYA Q67BJ2_CHICK Q67BJ2_CHICK -------------------------DGVCKTSDCIKSAARIIE-NMDTTAEPCNDFYQYA NEP_RABIT NEP_RABIT -------------------------DGICKSSDCIKSAARLIQ-NMDATAEPCTDFFKYA NEP_PONAB NEP_PONAB -------------------------DGICKSSDCIKSAARLIQ-NMDATAEPCTDFFKYA B7ZKY6_HUMAN B7ZKY6_HUMAN -------------------------DGICKSSDCIKSAARLIQ-NMDATTEPCTDFFKYA NEP_HUMAN NEP_HUMAN -------------------------DGICKSSDCIKSAARLIQ-NMDATTEPCTDFFKYA NEP_MOUSE NEP_MOUSE -------------------------DGICKSSDCIKSAARLIQ-NMDASVEPCTDFFKYA NEP_RAT NEP_RAT -------------------------DGICKSSDCIKSAARLIQ-NMDASAEPCTDFFKYA O93394_PERFV O93394_PERFV -------------------------DEICTTGDCTQSASRLIE-NMDDSVDPCDNFYQYA Q4SPQ9_TETNG Q4SPQ9_TETNG ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????C????C????????????D????PC??F????

Q4RZ05_TETNG Q4RZ05_TETNG CGGWLRRHGIPEDKLSYGIITAIGEHNEEKLQ---------------------------- Q5XHE7_XENLA Q5XHE7_XENLA CGGWLRRHGIPEDKLIYGTIAAIGEQNEEKLE---------------------------- ECEL1_HUMAN ECEL1_HUMAN CGGWLRRHAIPDDKLTYGTIAAIGEQNEERLR---------------------------- ECEL1_RAT ECEL1_RAT CGGWLRRHAIPDDKLTYGTIAAIGEQNEERLR---------------------------- ECEL1_MOUSE ECEL1_MOUSE CGGWLRRHAIPDDKLTYGTIAAIGEQNEERLR---------------------------- Q6PFG4_MOUSE Q6PFG4_MOUSE CGGWLRRHAIPDDKLTYGTIAAIGEQNEERLR---------------------------- Q3TX93_MOUSE Q3TX93_MOUSE CGGWLRRHAIPDDKLTYGTIAAIGEQNEERLR---------------------------- Q4SB05_TETNG Q4SB05_TETNG CGGWMRKNPLPDGRSHWSTFNSIGEQNQALLK---------------------------- B4DKF3_HUMAN B4DKF3_HUMAN CGGWIRRNPLPDGRSRWNTFNSLWDQNQAILK---------------------------- ECE2_BOVIN ECE2_BOVIN CGGWIRRNPLPDGRSRWNNSNSLWDQNQAILK---------------------------- Q865C2_BOVIN Q865C2_BOVIN CGGWIRRNPLPDGRSRWNNSNSLWDQNQAILK---------------------------- Q865C3_BOVIN Q865C3_BOVIN CGGWIRRNPLPDGRSRWNNSNSLWDQNQAILK---------------------------- B4DF19_HUMAN B4DF19_HUMAN CGGWIRRNPLPDGRSRWNTFNSLWDQNQAILK---------------------------- ECE2_HUMAN ECE2_HUMAN CGGWIRRNPLPDGRSRWNTFNSLWDQNQAILK---------------------------- B4DHU4_HUMAN B4DHU4_HUMAN ------------------------------------------------------------ Q6UW36_HUMAN Q6UW36_HUMAN CGGWIRRNPLPDGRSRWNTFNSLWDQNQAILK---------------------------- A5PLK8_HUMAN A5PLK8_HUMAN CGGWIRRNPLPDGRSRWNTFNSLWDQNQAILK---------------------------- Q8NFD7_HUMAN Q8NFD7_HUMAN CGGWIRRNPLPDGRSRWNTFNSLWDQNQAILK---------------------------- Q6IE65_RAT Q6IE65_RAT CGGWIRRNPLPSGRSRWNTFNSLWDQNQAILK---------------------------- ECE2_MOUSE ECE2_MOUSE CGGWIRRNPLPNGRSRWNTFNSLWDQNQAILK---------------------------- Q80Z57_MOUSE Q80Z57_MOUSE CGGWIRRNPLPNGRSRWNTFNSLWDQNQAILK---------------------------- Q80Z58_MOUSE Q80Z58_MOUSE CGGWIRRNPLPNGRSRWNTFNSLWDQNQAILK---------------------------- Q8K0P0_MOUSE Q8K0P0_MOUSE ------------------------------------------------------------ Q8C099_MOUSE Q8C099_MOUSE CGGWIRRNPLPNGRSRWNTFNSLWDQNQAILK---------------------------- B2RQR8_MOUSE B2RQR8_MOUSE CGGWIRRNPLPNGRSRWNTFNSLWDQNQAILK---------------------------- Q923T6_MOUSE Q923T6_MOUSE CGGWIRRNPLPNGRSRWNTFNSLWDQNQAILK---------------------------- Q4T614_TETNG Q4T614_TETNG CGGWMKSNPLPEGKSRWGTFSNLWEQNMLVMK---------------------------- A0JMP1_DANRE A0JMP1_DANRE CGGWMRKNPLPEGKSRWGPFSNLWEHNMAVMK---------------------------- A7LFV7_FUNHE A7LFV7_FUNHE ------------------------------------------------------------ Q32NT6_XENLA Q32NT6_XENLA CGGWIKGNPVPDGHSRWGTFNELWEHNQAIMK---------------------------- B6RBR2_XENLA B6RBR2_XENLA CGGWIKGNPVPDGHSRWGTFNELWEHNQAIMK---------------------------- Q7ZTK3_XENLA Q7ZTK3_XENLA CGGWIKGNPVPDGHSRWGTFNELWEHNQAIMK---------------------------- Q9DGN6_CHICK Q9DGN6_CHICK CGGWVKANPLPDGHSRWGTFNNLWEHNQAVMK---------------------------- ECE1_CAVPO ECE1_CAVPO CGGWIKANPVPDGHSRWGAFSNLWEHNQAIIK---------------------------- Q2Z2K8_HUMAN Q2Z2K8_HUMAN CGGWIKANPVPDGHSRWGTFSNLWEHNQAIIK---------------------------- B4DKB2_HUMAN B4DKB2_HUMAN CGGWIKANPVPDGHSRWGTFSNLWEHNQAIIK---------------------------- ECE1_HUMAN ECE1_HUMAN CGGWIKANPVPDGHSRWGTFSNLWEHNQAIIK---------------------------- ECE1_RAT ECE1_RAT CGGWIKANPVPDGHSRWGTFSNLWEHNQAIIK---------------------------- ECE1_MOUSE ECE1_MOUSE CGGWIKANPVPDGHSRWGTFSNLWEHNQAVIK---------------------------- Q6IN10_RAT Q6IN10_RAT CGGWIKANPVPDGHSRWGTFSNLWEHNQAIIK---------------------------- Q3HTT4_CANFA Q3HTT4_CANFA CGGWIKANPVPDGHSRWGTFSNLWEHNQAIIK---------------------------- ECE1_BOVIN ECE1_BOVIN CGGWIKANPVPDGHSRWGTFSNLWEHNQAIIK---------------------------- Q28010_BOVIN Q28010_BOVIN CGGWIKANPVPDGHSRWGTFSNLWEHNQAIIK---------------------------- Q28868_BOVIN Q28868_BOVIN CGGWIKANPVPDGHSRWGTFSNLWEHNQAIIK---------------------------- O35812_RAT O35812_RAT CDGWISNNPIPEDMPSYGVYPWLRHNVDLKLK---------------------------- A2ICR0_MOUSE A2ICR0_MOUSE CDGWISNNPIPEDMPSYGVYPWLRHNVDLKLK---------------------------- Q3TYM9_MOUSE Q3TYM9_MOUSE CDGWISNNPIPEDMPSYGVYPWLRHNVDLKLK---------------------------- PHEX_MOUSE PHEX_MOUSE CDGWISNNPIPEDMPSYGVYPWLRHNVDLKLK---------------------------- A2AC80_MOUSE A2AC80_MOUSE CDGWISNNPIPEDMPSYGVYPWLRHNVDLKLK---------------------------- B4E334_HUMAN B4E334_HUMAN ------------------------------------------------------------ B4DNS0_HUMAN B4DNS0_HUMAN CDGWISNNPIPEDMPSYGVYPWLRHNVDLKLK---------------------------- B4DWG8_HUMAN B4DWG8_HUMAN -------------MPSYGVYPWLRHNVDLKLK---------------------------- PHEX_HUMAN PHEX_HUMAN CDGWISNNPIPEDMPSYGVYPWLRHNVDLKLK---------------------------- A4QP66_DANRE A4QP66_DANRE ------------------------------------------------------------ Q4S1N5_TETNG Q4S1N5_TETNG CGGWIKENPIPEDSSSYGIYPWLRQEVDIRLK---------------------------- B9DI79_HUMAN B9DI79_HUMAN CGGWLRRHVIPETNSRYSIFDVLRDELEVILK---------------------------- MMEL1_HUMAN MMEL1_HUMAN CGGWLRRHVIPETNSRYSIFDVLRDELEVILK---------------------------- B3KS82_HUMAN B3KS82_HUMAN CGGWLRRHVIPETNSRYSIFDVLRDELEVILK---------------------------- MMEL1_RAT MMEL1_RAT CGGWLRHHVIPETNSRYSVFDILRDELEVILK---------------------------- B1AS15_MOUSE B1AS15_MOUSE CGGWLRHHVIPETNSRYSVFDILRDELEVILK---------------------------- B1AS16_MOUSE B1AS16_MOUSE CGGWLRHHVIPETNSRYSVFDILRDELEVILK---------------------------- B1AS17_MOUSE B1AS17_MOUSE CGGWLRHHVIPETNSRYSVFDILRDELEVILK---------------------------- B2RPX5_MOUSE B2RPX5_MOUSE CGGWLRHHVIPETNSRYSVFDILRDELEVILK---------------------------- MMEL1_MOUSE MMEL1_MOUSE CGGWLRHHVIPETNSRYSVFDILRDELEVILK---------------------------- Q4RX51_TETNG Q4RX51_TETNG CGGWLERHVIPETSSRHSVFDILRDKLEIVLKGQLTPTASGAPPSFSDDIFFALPECSVV B1WAX2_XENTR B1WAX2_XENTR CGGWLNKHVIPETSSRYSIFDILRDEMEIILK---------------------------- Q67BJ2_CHICK Q67BJ2_CHICK CGGWLKRNVIPETSSRYSNFDILRDELEVVLK---------------------------- NEP_RABIT NEP_RABIT CGGWLKRNVIPETSSRYSNFDILRDELEVILK---------------------------- NEP_PONAB NEP_PONAB CGGWLKRNVIPETSSRYGNFDILRDELEVVLK---------------------------- B7ZKY6_HUMAN B7ZKY6_HUMAN CGGWLKRNVIPETSSRYGNFDILRDELEVVLK---------------------------- NEP_HUMAN NEP_HUMAN CGGWLKRNVIPETSSRYGNFDILRDELEVVLK---------------------------- NEP_MOUSE NEP_MOUSE CGGWLKRNVIPETSSRYSNFDILRDELEVILK---------------------------- NEP_RAT NEP_RAT CGGWLKRNVIPETSSRYSNFDILRDELEVILK---------------------------- O93394_PERFV O93394_PERFV CGGWLKKNIIPETSSRYSTFDILRDELEVILK---------------------------- Q4SPQ9_TETNG Q4SPQ9_TETNG -----------------------------VFA---------------------------- MATCH CONSENSUS CGGW??????P???????????L????????K????????????????????????????

Q4RZ05_TETNG Q4RZ05_TETNG -RLLLDPIQRRGPNSAERKVKEFYRSCINIQEIDKLGSEPMMEVIK-------------- Q5XHE7_XENLA Q5XHE7_XENLA -HLLLQPVKRKHKGSAEKKVKEFFKSCLNMRDIDRLGARPMLQVIE-------------- ECEL1_HUMAN ECEL1_HUMAN -RLLARPGG-GPGGAAQRKVRAFFRSCLDMREIERLGPRPMLEVIE-------------- ECEL1_RAT ECEL1_RAT -RLLARPTG-GPGGAAQRKVRAFFRSCLDMREIERLGPRPMLEVIE-------------- ECEL1_MOUSE ECEL1_MOUSE -RLLARPTG-GPGGAAQRKVRAFFRSCLDMREIERLGPRPMLEVIE-------------- Q6PFG4_MOUSE Q6PFG4_MOUSE -RLLARPTG-GPGGAAQRKVRAFFRSCLDMREIERLGPRPMLEVIE-------------- Q3TX93_MOUSE Q3TX93_MOUSE -RLLARPTG-GPGGAAQRKVRAFFRSCLDMREIERLGPRPMLEVIE-------------- Q4SB05_TETNG Q4SB05_TETNG -HLLENGTF-NSSSEAEKKAQFYYLSCLNTQKIEELGAQPLTDLIA-------------- B4DKF3_HUMAN B4DKF3_HUMAN -HLLENTTF-NSSSEAEQKTQRFYLSCLQVERIEELGAQPLRDLIE-------------- ECE2_BOVIN ECE2_BOVIN -HLLENTTF-NSSSEAERKTQRFYLSCLQVERIEELGAHALRDLID-------------- Q865C2_BOVIN Q865C2_BOVIN -HLLENTTF-NSSSEAERKTQRFYLSCLQVERIEELGAHALRDLID-------------- Q865C3_BOVIN Q865C3_BOVIN -HLLENTTF-NSSSEAERKTQRFYLSCLQVERIEELGAHALRDLID-------------- B4DF19_HUMAN B4DF19_HUMAN -HLLENTTF-NSSSEAEQKTQRFYLSCLQVERIEELGAQPLRDLIE-------------- ECE2_HUMAN ECE2_HUMAN -HLLENTTF-NSSSEAEQKTQRFYLSCLQVERIEELGAQPLRDLIE-------------- B4DHU4_HUMAN B4DHU4_HUMAN ------------------------------------------------------------ Q6UW36_HUMAN Q6UW36_HUMAN -HLLENTTF-NSSSEAEQKTQRFYLSCLQVERIEELGAQPLRDLIE-------------- A5PLK8_HUMAN A5PLK8_HUMAN -HLLENTTF-NSSSEAEQKTQRFYLSCLQVERIEELGAQPLRDLIE-------------- Q8NFD7_HUMAN Q8NFD7_HUMAN -HLLENTTF-NSSSEAEQKTQRFYLSCLQVERIEELGAQPLRDLIE-------------- Q6IE65_RAT Q6IE65_RAT -HLLENSTF-NSSSEAERKTRSFYLSCLHLERIEKLGAKPLQDLID-------------- ECE2_MOUSE ECE2_MOUSE -HLLENTTF-NSSSEAERKTRSFYLSCLQSERIEKLGAKPLRDLID-------------- Q80Z57_MOUSE Q80Z57_MOUSE -HLLENTTF-NSSSEAERKTRSFYLSCLQSERIEKLGAKPLRDLID-------------- Q80Z58_MOUSE Q80Z58_MOUSE -HLLENTTF-NSSSEAERKTRSFYLSCLQSERIEKLGAKPLRDLID-------------- Q8K0P0_MOUSE Q8K0P0_MOUSE ------------------------------------------------------------ Q8C099_MOUSE Q8C099_MOUSE -HLLENTTF-NSSSEAERKTRSFYLSCLQSERIEKLGAKPLRDLID-------------- B2RQR8_MOUSE B2RQR8_MOUSE -HLLENTTF-NSSSEAERKTRSFYLSCLQSERIEKLGAKPLRDLID-------------- Q923T6_MOUSE Q923T6_MOUSE -HLLENTTF-NSSSEAERKTRSFYLSCLQSERIEKLGAKPLRDLID-------------- Q4T614_TETNG Q4T614_TETNG -RLLENTSR-EGLSGAEEKAQRYYQACMNEAKIEELGAKPLQEVISRVRRPPAGHLERLA A0JMP1_DANRE A0JMP1_DANRE -NLLENTSM-KSLSRAEQKAQWYYQACMNESKIEELGAKPLQDLIN-------------- A7LFV7_FUNHE A7LFV7_FUNHE ------------------------------------GAKPLQRLIS-------------- Q32NT6_XENLA Q32NT6_XENLA -HLLENSTM-NTSSTAEHKAQSYFQACMNESKIEELGAKPLQDLIQ-------------- B6RBR2_XENLA B6RBR2_XENLA -HLLENSTM-NTSSTAEHKAQSYFQACMNESKIEELGAKPLQDLIQ-------------- Q7ZTK3_XENLA Q7ZTK3_XENLA -HLLENSTM-NTSSTAEHKAQSYFQACMNESKIEELGAKPLQDLIQ-------------- Q9DGN6_CHICK Q9DGN6_CHICK -HLLENTTA-NVSSEAERKAQRYYQACMNESKIEELRAAPLMELIA-------------- ECE1_CAVPO ECE1_CAVPO -HLLENSTA--SVSEAERKAQVYYRACMNETRIEELRAKPLMELIE-------------- Q2Z2K8_HUMAN Q2Z2K8_HUMAN -HLLENSTA--SVSEAERKAQVYYRACMNETRIEELRAKPLMELIE-------------- B4DKB2_HUMAN B4DKB2_HUMAN -HLLENSTA--SVSEAERKAQVYYRACMNETRIEELRAKPLMELIE-------------- ECE1_HUMAN ECE1_HUMAN -HLLENSTA--SVSEAERKAQVYYRACMNETRIEELRAKPLMELIE-------------- ECE1_RAT ECE1_RAT -HLLENSTA--SASEAEKKAQVYYRACMNETRIEELRAKPLMELIE-------------- ECE1_MOUSE ECE1_MOUSE -HLLENATA--SVSEAERKAQVYYRACMNETRIEELRAKPLMELIE-------------- Q6IN10_RAT Q6IN10_RAT -HLLENSTA--SASEAEKKAQVYYRACMNETRIEELRAKPLMELIE-------------- Q3HTT4_CANFA Q3HTT4_CANFA -HLLENSTA--SVSEAERKAQVYYXACMNETRIEELKAKPLMELIE-------------- ECE1_BOVIN ECE1_BOVIN -HLLENSTA--SVSEAERKAQVYYRACMNETRIEELKAKPLMELIE-------------- Q28010_BOVIN Q28010_BOVIN -HLLENSTA--SVSEAERKAQVYYRACMNETRIEELKAKPLMELIE-------------- Q28868_BOVIN Q28868_BOVIN -HLLENSTA--SVSEAERKAQVYYRACMNETRIEELKAKPLMELIE-------------- O35812_RAT O35812_RAT -ALLEKSVSRRRDTEAVQKAKILYSSCMNEKAIEKADAKPLLHILRH------------- A2ICR0_MOUSE A2ICR0_MOUSE -ALLEKSVSRRRDTEAVQKAKILYSSCMNEKAIEKADAKPLLHILRH------------- Q3TYM9_MOUSE Q3TYM9_MOUSE -ALLEKSVSRRRDTEAVQKAKILYSSCMNEKAIEKADAKPLLHILRH------------- PHEX_MOUSE PHEX_MOUSE -ALLEKSVSRRRDTEAVQKAKILYSSCMNEKAIEKADAKPLLHILRH------------- A2AC80_MOUSE A2AC80_MOUSE -ALLEKSVSRRRDTEAVQKAKILYSSCMNEKAIEKADAKPLLHILRH------------- B4E334_HUMAN B4E334_HUMAN ------------------------------------------------------------ B4DNS0_HUMAN B4DNS0_HUMAN -ELLEKSISRRRDTEAIQKAKILYSSCMNEKAIEKADAKPLLHILRH------------- B4DWG8_HUMAN B4DWG8_HUMAN -ELLEKSISRRRDTEAIQKAKILYSSCMNEKAIEKADAKPLLHILRH------------- PHEX_HUMAN PHEX_HUMAN -ELLEKSISRRRDTEAIQKAKILYSSCMNEKAIEKADAKPLLHILRH------------- A4QP66_DANRE A4QP66_DANRE ---------------------------MNESALEIEDANPLLKNLKQ------------- Q4S1N5_TETNG Q4S1N5_TETNG -ELLEAPAD-AAELEAVGKAKVLYRSCMNETVLEKLDSKPMLKTLKQ------------- B9DI79_HUMAN B9DI79_HUMAN -AVLENSTA--KDRPAVEKARTLYRSCMNQSVIEKRGSQPLLDILE-------------- MMEL1_HUMAN MMEL1_HUMAN -AVLENSTA--KDRPAVEKARTLYRSCMNQSVIEKRGSQPLLDILE-------------- B3KS82_HUMAN B3KS82_HUMAN -AVLENSTA--KDRPAVEKARTLYRSCMNQSVIEKRGSQPLLDILE-------------- MMEL1_RAT MMEL1_RAT -GVLEDSSV--QHRPAVEKAKTLYRSCMNQSVIEKRDSEPLLNVLD-------------- B1AS15_MOUSE B1AS15_MOUSE -GVLEDSTS--QHRPAVEKAKTLYRSCMNQSVIEKRDSEPLLSVLK-------------- B1AS16_MOUSE B1AS16_MOUSE -GVLEDSTS--QHRPAVEKAKTLYRSCMNQSVIEKRDSEPLLSVLK-------------- B1AS17_MOUSE B1AS17_MOUSE -GVLEDSTS--QHRPAVEKAKTLYRSCMNQSVIEKRDSEPLLSVLK-------------- B2RPX5_MOUSE B2RPX5_MOUSE -GVLEDSTS--QHRPAVEKAKTLYRSCMNQSVIEKRDSEPLLSVLK-------------- MMEL1_MOUSE MMEL1_MOUSE -GVLEDSTS--QHRPAVEKAKTLYRSCMNQSVIEKRDSEPLLSVLK-------------- Q4RX51_TETNG Q4RX51_TETNG AGVLETESK--QDRDAIRKAKALYSSCMNESLIEQRDSQPLLKLIE-------------- B1WAX2_XENTR B1WAX2_XENTR -GLLEMPDQ--EDRDAFKKAKILYKSCMNESLIEQRDSLPLLELLT-------------- Q67BJ2_CHICK Q67BJ2_CHICK -DVLDTPSS--NDITAVQKAKTLYRSCINETTIDSRGGMPLISLLA-------------- NEP_RABIT NEP_RABIT -DVLQEPKT--EDIVAVQKAKTLYRSCVNETAIDSRGGQPLLKLLP-------------- NEP_PONAB NEP_PONAB -DVLQEPKT--EDIVAVQKAKTLYRSCINESAIDSRGGEPLLKLLP-------------- B7ZKY6_HUMAN B7ZKY6_HUMAN -DVLQEPKT--EDIVAVQKAKALYRSCINESAIDSRGGEPLLKLLP-------------- NEP_HUMAN NEP_HUMAN -DVLQEPKT--EDIVAVQKAKALYRSCINESAIDSRGGEPLLKLLP-------------- NEP_MOUSE NEP_MOUSE -DVLQEPKT--EDIVAVQKAKTLYRSCINESAIDSRGGQPLLKLLP-------------- NEP_RAT NEP_RAT -DVLQEPKT--EDIVAVQKAKTLYRSCINESAIDSRGGQPLLTLLP-------------- O93394_PERFV O93394_PERFV -GVLEKTDE--GEATLSTRAKTLYKSCTNESLIELRGGAPLLDMLP-------------- Q4SPQ9_TETNG Q4SPQ9_TETNG -EVLEKTVE--GEPAALTKAKTLYQSCIGDREIERRGGAPLLNMLP-------------- MATCH CONSENSUS ???L???????????A??K????Y??C?????IE?????PL???????????????????

Q4RZ05_TETNG Q4RZ05_TETNG -----------SCGGWDLAGAPPGAAG--WETEGAAQRPDFNELLYRTQGVYSTAVFFSL Q5XHE7_XENLA Q5XHE7_XENLA -----------DCGGWDL----PEDPKTQWD---------FNELLYKTQGVYSTAVFFSM ECEL1_HUMAN ECEL1_HUMAN -----------DCGGWDL----GGA----EERPGVAARWDLNRLLYKAQGVYSAAALFSL ECEL1_RAT ECEL1_RAT -----------DCGGWDLGGAADRPGAARWD---------LNRLLYKAQGVYSAAALFSL ECEL1_MOUSE ECEL1_MOUSE -----------DCGGWDLGGAADRPGAARWD---------LNRLLYKAQGVYSAAALFSL Q6PFG4_MOUSE Q6PFG4_MOUSE -----------DCGGWDLGGAADRPGAARWD---------LNRLLYKAQGVYSAAALFSL Q3TX93_MOUSE Q3TX93_MOUSE -----------DCGGWDLGDAADRPGAARWD---------LNRLLYKAQGVYSAAALFSL Q4SB05_TETNG Q4SB05_TETNG -----------KIGGWNI----TGP----WDKDN------FMEVLKVVSGPYRAQPFFSV B4DKF3_HUMAN B4DKF3_HUMAN -----------KIGGWNI----TGP----WDQDN------FMEVLKAVAGTYRATPFFTV ECE2_BOVIN ECE2_BOVIN -----------KIGGWNV----TGP----WDQDN------FMEVLKAVAGTYRATPFFTV Q865C2_BOVIN Q865C2_BOVIN -----------KIGGWNV----TGP----WDQDN------FMEVLKAVAGTYRATPFFTV Q865C3_BOVIN Q865C3_BOVIN -----------KIGGWNV----TGP----WDQDN------FMEVLKAVAGTYRATPFFTV B4DF19_HUMAN B4DF19_HUMAN -----------KIGGWNI----TGP----WDQDN------FMEVLKAVAGTYRATPFFTV ECE2_HUMAN ECE2_HUMAN -----------KIGGWNI----TGP----WDQDN------FMEVLKAVAGTYRATPFFTV B4DHU4_HUMAN B4DHU4_HUMAN ------------------------------------------------------------ Q6UW36_HUMAN Q6UW36_HUMAN -----------KIGGWNI----TGP----WDQDN------FMEVLKAVAGTYRATPFFTV A5PLK8_HUMAN A5PLK8_HUMAN -----------KIGGWNI----TGP----WDQDN------FMEVLKAVAGTYRATPFFTV Q8NFD7_HUMAN Q8NFD7_HUMAN -----------KIGGWNI----TGP----WDQDN------FMEVLKAVAGTYRATPFFTV Q6IE65_RAT Q6IE65_RAT -----------KIGGWNI----TGP----WDEDN------FMEVLKAVAGTYRAAPFFTV ECE2_MOUSE ECE2_MOUSE -----------KIGGWNI----TGP----WDEDS------FMDVLKAVAGTYRATPFFTV Q80Z57_MOUSE Q80Z57_MOUSE -----------KIGGWNI----TGP----WDEDS------FMDVLKAVAGTYRATPFFTV Q80Z58_MOUSE Q80Z58_MOUSE -----------KIGGWNI----TGP----WDEDS------FMDVLKAVAGTYRATPFFTV Q8K0P0_MOUSE Q8K0P0_MOUSE ------------------------------------------------------------ Q8C099_MOUSE Q8C099_MOUSE -----------KIGGWNI----TGP----WDEDS------FMDVLKAVAGTYRATPFFTV B2RQR8_MOUSE B2RQR8_MOUSE -----------KIGGWNI----TGP----WDEDS------FMDVLKAVAGTYRATPFFTV Q923T6_MOUSE Q923T6_MOUSE -----------KIGGWNI----TGP----WDEDS------FMDVLKAVAGTYRATPFFTV Q4T614_TETNG Q4T614_TETNG RIPLTVCLNTLQIGGWAL----TEP----WDKDN------FQEVLRLVSADYRTSPFFSV A0JMP1_DANRE A0JMP1_DANRE -----------QTGGWGL----KGP----WEKDN------FQEVLRIVSANFRTSPFFTV A7LFV7_FUNHE A7LFV7_FUNHE -----------KIGGWAL----TEP----WDKDN------FQEVLRTVSASLRTSPFFTV Q32NT6_XENLA Q32NT6_XENLA -----------KLGGWSI----IGP----WDKDN------FQETLQLVTAHYRTSPFFSV B6RBR2_XENLA B6RBR2_XENLA -----------KLGGWSI----TGP----WDKDN------FQETLQLVTAHYRTSPFFSV Q7ZTK3_XENLA Q7ZTK3_XENLA -----------KLGGWSI----TGP----WDKDN------FQETLQLVTAHYRTSPFFSV Q9DGN6_CHICK Q9DGN6_CHICK -----------KLGGWNI----TGP----WAGGD------FNATLREVTAHYRISPFFSV ECE1_CAVPO ECE1_CAVPO -----------KLGGWNI----TGP----WAKDN------FQDTLQVVTAHYRTSPFFSV Q2Z2K8_HUMAN Q2Z2K8_HUMAN -----------RLGGWNI----TGP----WAKDN------FQDTLQVVTAHYRTSPFFSV B4DKB2_HUMAN B4DKB2_HUMAN -----------RLGGWNI----TGP----WAKDN------FQDTLQVVTAHYRTSPFFSV ECE1_HUMAN ECE1_HUMAN -----------RLGGWNI----TGP----WAKDN------FQDTLQVVTAHYRTSPFFSV ECE1_RAT ECE1_RAT -----------KLGGWNI----TGP----WAKDN------FQDTLQVVTAHYRTSPFFSV ECE1_MOUSE ECE1_MOUSE -----------KLGGWNI----TGP----WAKDN------FQDTLQVVTAHYRTSPFFSV Q6IN10_RAT Q6IN10_RAT -----------KLGGWNI----TGP----WAKDN------FQDTLQVVTAHYRTSPFFSV Q3HTT4_CANFA Q3HTT4_CANFA -----------KLGGWNI----TGP----WDKDN------FQDTLQVVTSHYRTSPFFSV ECE1_BOVIN ECE1_BOVIN -----------KLGGWNI----TGP----WDKDN------FQDTLQVVTSHYHTSPFFSV Q28010_BOVIN Q28010_BOVIN -----------KLGGWNI----TGP----WDKDN------FQDTLQVVTSHYHTSPFFSV Q28868_BOVIN Q28868_BOVIN -----------KLGGWNI----TGP----WDKDN------FQDTLQVVTSHYHTSPFFSV O35812_RAT O35812_RAT -----------SPFRWPVLEANIGPEGV-WSERK----FSLLQTLATFRGQYSNSVFIRL A2ICR0_MOUSE A2ICR0_MOUSE -----------SPFRWPVLEANIGPEGV-WSERK----FSLLQTLATFRGQYSNSVFIRL Q3TYM9_MOUSE Q3TYM9_MOUSE -----------SPFRWPVLEANIGPEGV-WSERK----FSLLQTLATFRGQYSNSVFIRL PHEX_MOUSE PHEX_MOUSE -----------SPFRWPVLEANIGPEGV-WSERK----FSLLQTLATFRGQYSNSVFIRL A2AC80_MOUSE A2AC80_MOUSE -----------SPFRWPVLEANIGPEGV-WSERK----FSLLQTLATFRGQYSNSVFIRL B4E334_HUMAN B4E334_HUMAN ------------------------------------------------------------ B4DNS0_HUMAN B4DNS0_HUMAN -----------SPFRWPVLESNIGPEGV-WSERK----FSLLQTLATFRGQYSNSVFIRL B4DWG8_HUMAN B4DWG8_HUMAN -----------SPFRWPVLESNIGPEGV-WSERK----FSLLQTLATFRGQYSNSVFIRL PHEX_HUMAN PHEX_HUMAN -----------SPFRWPVLESNIGPEGV-WSERK----FSLLQTLATFRGQYSNSVFIRL A4QP66_DANRE A4QP66_DANRE -----------KEFRWPVLGDALGSSSR-WVESQ----FNLLETLAQIRSQHSKSVLIRL Q4S1N5_TETNG Q4S1N5_TETNG -----------PEFRWPVVGDGLKGEYQ-WSAGQ----WSLLKTLADMRNLHSKSVLVRL B9DI79_HUMAN B9DI79_HUMAN -----------VVGGWPV----AMDR---WNETV-GLEWELERQLALMNSQFNRRVLIDL MMEL1_HUMAN MMEL1_HUMAN -----------VVGGWPV----AMDR---WNETV-GLEWELERQLALMNSQFNRRVLIDL B3KS82_HUMAN B3KS82_HUMAN -----------VVGGWPV----AMDR---WNETV-GLKWELERQLALMNSQFNRRVLIDL MMEL1_RAT MMEL1_RAT -----------MIGGWPV----AMDK---WNETM-GPKWELERQLAVLNSQFNRRVLIDL B1AS15_MOUSE B1AS15_MOUSE -----------MVGGWPV----AMDK---WNETM-GLKWELERQLAVLNSQFNRRVLIDL B1AS16_MOUSE B1AS16_MOUSE -----------MVGGWPV----AMDK---WNETM-GLKWELERQLAVLNSQFNRRVLIDL B1AS17_MOUSE B1AS17_MOUSE -----------MVGGWPV----AMDK---WNETM-GLKWELERQLAVLNSQFNRRVLIDL B2RPX5_MOUSE B2RPX5_MOUSE -----------MVGGWPV----AMDK---WNETM-GLKWELERQLAVLNSQFNRRVLIDL MMEL1_MOUSE MMEL1_MOUSE -----------MVGGWPV----AMDK---WNETM-GLKWELERQLAVLNSQFNRRVLIDL Q4RX51_TETNG Q4RX51_TETNG -----------SIGDWPA----ASED---WNTTT-EEAWSLEDTLATLTARFHKKVLLDM B1WAX2_XENTR B1WAX2_XENTR -----------TVGEWPV----ASTD---WNGTK-ESNWSLEEKLSLLNYKFNKRVLVDI Q67BJ2_CHICK Q67BJ2_CHICK -----------NLSEWPV----ATNN---WESSY-GAAWTAETAIAQLTSRYGKKVLINF NEP_RABIT NEP_RABIT -----------DVYGWPV----ATQN---WEQTY-GTSWSAEKSIAQLNSNYGKKVLINF NEP_PONAB NEP_PONAB -----------DVYGWPV----ATEN---WEQKY-GASWTAEKAIAQLNSKYGKKVLINL B7ZKY6_HUMAN B7ZKY6_HUMAN -----------DIYGWPV----ATEN---WEQKY-GASWTAEKAIAQLNSKYGKKVLINL NEP_HUMAN NEP_HUMAN -----------DIYGWPV----ATEN---WEQKY-GASWTAEKAIAQLNSKYGKKVLINL NEP_MOUSE NEP_MOUSE -----------DIYGWPV----ASDN---WDQTY-GTSWTAEKSIAQLNSKYGKKVLINF NEP_RAT NEP_RAT -----------DIYGWPV----ASQN---WEQTY-GTSWTAEKSIAQLNSKYGKKVLINF O93394_PERFV O93394_PERFV -----------DVFEWPV----AVDN---WETNY-GKTWRLEDVIAKLNEKYGTQLLVNF Q4SPQ9_TETNG Q4SPQ9_TETNG -----------DVYDWPI----AVDN---WEAEY-GKLWRLEDVIAKLNVKYGSQLVINF MATCH CONSENSUS ???????????????W?????????????W??????????????L???????????????

Q4RZ05_TETNG Q4RZ05_TETNG TVNVDDKNSSRNAIRVDQEG-LTLPERSLYLGQDEDSVKILAAYKALMERLLSM------ Q5XHE7_XENLA Q5XHE7_XENLA AVSLDDKNSSRYIIRIDQDG-LTLPERTLYLGQDEESIKILEAYKVFMQTILSL------ ECEL1_HUMAN ECEL1_HUMAN TVSLDDRNSSRYVIRIDQDG-LTLPERTLYLAQDEDSEKILAAYRVFMERVLSL------ ECEL1_RAT ECEL1_RAT TVSLDDRNSSRYVIRIDQDG-LTLPERTLYLAQDEGSEKVLAAYKVFMERLLRL------ ECEL1_MOUSE ECEL1_MOUSE TVSLDDRNSSRYVIRIDQDG-LTLPERTLYLAQDEESEKILAAYRVFMQRLLRL------ Q6PFG4_MOUSE Q6PFG4_MOUSE TVSLDDRNSSRYVIRIDQDG-LTLPERTLYLAQDEESEKILAAYRVFMQRLLRL------ Q3TX93_MOUSE Q3TX93_MOUSE TVSLDDRNSSRYVIRIDQDG-LTLPERTLYLAQDEESEKILAAYRVFMQRLLRL------ Q4SB05_TETNG Q4SB05_TETNG GVSADPKNSNSNVIQVDQSG-LFLPSR-DYYLNKTADDKVLVAYLDYMVELGTL------ B4DKF3_HUMAN B4DKF3_HUMAN YISADSKSSNSNVIQVDQSG-LFLPSR-DYYLNRTANEKVLTAYLDYMEELGML------ ECE2_BOVIN ECE2_BOVIN YVSADSKSSNSNIIQVDQSG-LFLPSR-DYYLNRTANEKVLTAYLDYMEELGML------ Q865C2_BOVIN Q865C2_BOVIN YVSADSKSSNSNIIQVDQSG-LFLPSR-DYYLNRTANEKVLTAYLDYMEELGML------ Q865C3_BOVIN Q865C3_BOVIN YVSADSKSSNSNIIQVDQSG-LFLPSR-DYYLNRTANEKVLTAYLDYMEELGML------ B4DF19_HUMAN B4DF19_HUMAN YISADSKSSNSNVIQVDQSG-LFLPSR-DYYLNRTANEKVLTAYLDYMEELGML------ ECE2_HUMAN ECE2_HUMAN YISADSKSSNSNVIQVDQSG-LFLPSR-DYYLNRTANEKVLTAYLDYMEELGML------ B4DHU4_HUMAN B4DHU4_HUMAN -----------------------------------------------MEELGML------ Q6UW36_HUMAN Q6UW36_HUMAN YISADSKSSNSNVIQVDQSG-LFLPSR-DYYLNRTANEKVLTAYLDYMEELGML------ A5PLK8_HUMAN A5PLK8_HUMAN YISADSKSSNSNVIQVDQSG-LFLPSR-DYYLNRTANEKVLTAYLDYMEELGML------ Q8NFD7_HUMAN Q8NFD7_HUMAN YISADSKSSNSNVIQVDQSG-LFLPSR-DYYLNRTANEKVLTAYLDYMEELGML------ Q6IE65_RAT Q6IE65_RAT YVGADSKSSNSNIIQVDQSG-LFLPSR-DYYLNRTANEKVLAAYLDYMVELGML------ ECE2_MOUSE ECE2_MOUSE YVSADSKRSYSNITQVDQSG-LFLPSR-DYYLNRTANEKVLTAYLDYMVELGVL------ Q80Z57_MOUSE Q80Z57_MOUSE YVSADSKRSYSNITQVDQSG-LFLPSR-DYYLNRTANEKVLTAYLDYMVELGVL------ Q80Z58_MOUSE Q80Z58_MOUSE YVSADSKRSYSNITQVDQSG-LFLPSR-DYYLNRTANEKVLTAYLDYMVELGVL------ Q8K0P0_MOUSE Q8K0P0_MOUSE -------SSNSNIIQVDQSG-LFLPSR-DYYLNRTANEKVLTAYLDYMVELGVL------ Q8C099_MOUSE Q8C099_MOUSE YVSADSKSSNSNIIQVDQSG-LFLPSR-DYYLNRTANEKVLTAYLDYMVELGVL------ B2RQR8_MOUSE B2RQR8_MOUSE YVSADSKSSNSNIIQVDQSG-LFLPSR-DYYLNRTANEKVLTAYLDYMVELGVL------ Q923T6_MOUSE Q923T6_MOUSE YVSADSKSSNSNIIQVDQSG-LFLPSR-DYYLNRTANEKVLTAYLDYMVELGVL------ Q4T614_TETNG Q4T614_TETNG FVSTDSKNSNSNVIQIDQSS-LGLPSR-DYYLNRTAHEKYLSAYQTFLVELGVL------ A0JMP1_DANRE A0JMP1_DANRE FVSTDSKSSNSNIIQVDQSG-LGLPSR-EYYLNKTANEKYLNAYLNFLVELGVL------ A7LFV7_FUNHE A7LFV7_FUNHE FVSTDSKNSNSNVIQVDQSS-LGLPSR-EYYLNKTANEKYLTAYLNFLVELGVL------ Q32NT6_XENLA Q32NT6_XENLA FVSADSKNSNSNVIQIDQSG-LGLPSM-EYYLNKTMNEKVLTGYLNFMVQLGVL------ B6RBR2_XENLA B6RBR2_XENLA FVSADSKNSNSNVIQIDQSG-LGLPSM-EYYLNKTMNEKVLTGYLNFMVQLGVL------ Q7ZTK3_XENLA Q7ZTK3_XENLA FVSADSKNSNSNVIQIDQSG-LGLPSM-EYYLNKTMNEKVLTGYLNFMVQLGVL------ Q9DGN6_CHICK Q9DGN6_CHICK YVSADSKNSNSNVIQVDQSG-LGLPSR-DYYLNKTENEKVLAGYLNYMVQLGMF------ ECE1_CAVPO ECE1_CAVPO YVSADSKNSNRNVIHVDQSG-LGLPSR-DYYLNKTENEKVLNGYLNYMVQLGKL------ Q2Z2K8_HUMAN Q2Z2K8_HUMAN YVSADSKNSNSNVIQVDQSG-LGLPSR-DYYLNKTENEKVLTGYLNYMVQLGKL------ B4DKB2_HUMAN B4DKB2_HUMAN YVSADSKNSNSNVIQVDQSG-LGLPSR-DYYLNKTENEKVLTGYLNYMVQLGKL------ ECE1_HUMAN ECE1_HUMAN YVSADSKNSNSNVIQVDQSG-LGLPSR-DYYLNKTENEKVLTGYLNYMVQLGKL------ ECE1_RAT ECE1_RAT YVSADSKNSNSNVIQVDQSG-LGLPSR-DYYLNKTENEKVLTGYLNYMVQLGKL------ ECE1_MOUSE ECE1_MOUSE YVSADSKNSNSNVIQVDQSG-LGLPSR-DYYLNKTENEKVLTGYLNYMVQLGKL------ Q6IN10_RAT Q6IN10_RAT YVSADSKNSNSNVIQVDQSG-LGLPSR-DYYLNKTENEKVLTGYLNYMVQLGKL------ Q3HTT4_CANFA Q3HTT4_CANFA YVSADSKNSNSNVIQVDQSG-LGLPSR-DYYLNKTENEKVLTGYLNYMVQLGKL------ ECE1_BOVIN ECE1_BOVIN YVSADSKNSNSNVIQVDQSG-LGLPSR-DYYLNKTENEKVLTGYLNYMVQLGKL------ Q28010_BOVIN Q28010_BOVIN YVSADSKNSNSNVIQVDQSG-LGLPSR-DYYLNKTENEKVLTGYLNYMVQLGKL------ Q28868_BOVIN Q28868_BOVIN YVSADSKNSNSNVIQVDQSG-LGLPSR-DYYLNKTENEKVLTGYLNYMVQLGKL------ O35812_RAT O35812_RAT YVSPDDKASNEHILKLDQAT-LSLAVREDFLDNTTEAKSYRDALYKFMVDTAVL------ A2ICR0_MOUSE A2ICR0_MOUSE YVSPDDKASNEHILKLDQAT-LSLAVREDFLDNTTEAKSYRDALYKFMVDTAVL------ Q3TYM9_MOUSE Q3TYM9_MOUSE YVSPDDKASNEHILKLDQAT-LSLAVREDFLDNTTEAKSYRDALYKFMVDTAVL------ PHEX_MOUSE PHEX_MOUSE YVSPDDKASNEHILKLDQAT-LSLAVREDFLDNTTEAKSYRDALYKFMVDTAVL------ A2AC80_MOUSE A2AC80_MOUSE YVSPDDKASNEHILKLDQAT-LSLAVREDFLDNTTEAKSYRDALYKFMVDTAVL------ B4E334_HUMAN B4E334_HUMAN ------------MIHLPRPP---------------------------------------- B4DNS0_HUMAN B4DNS0_HUMAN YVSPDDKASNEHILKLDQAT-LSLAVREDYLDNSTEAKSYRDALYKFMVDTAVL------ B4DWG8_HUMAN B4DWG8_HUMAN YVSPDDKASNEHILKLDQAT-LSLAVREDYLDNSTEAKSYRDALYKFMVDTAVL------ PHEX_HUMAN PHEX_HUMAN YVSPDDKASNEHILKLDQAT-LSLAVREDYLDNSTEAKSYRDALYKFMVDTAVL------ A4QP66_DANRE A4QP66_DANRE FVAPDDKNSNQYIIKLDQAS-LSLSSREDYITNTTEAQMYREALLRLMVDVSVM------ Q4S1N5_TETNG Q4S1N5_TETNG YVSPDDKNSSHYVIKLDQAS-LSLPSREDYTTNSSSAQAYRAALLSLMVDVAVM------ B9DI79_HUMAN B9DI79_HUMAN FIWNDDQNSSRHIIYIDQPT-LGMPSR-EYYFNGGSNRKVREAYLQFMVSVATLLREDAN MMEL1_HUMAN MMEL1_HUMAN FIWNDDQNSSRHIIYIDQPT-LGMPSR-EYYFNGGSNRKVREAYLQFMVSVATLLREDAN B3KS82_HUMAN B3KS82_HUMAN FIWNDDQNSSRHIIYIDQPT-LGMPSR-EYYFNGGSNRKVREAYLQFMVSVATLLREDAN MMEL1_RAT MMEL1_RAT FIWNDDQNSSRHVIYIDQPT-LGMPSR-EYYF-KEDSHRVREAYLQFMTSVATMLRRDLN B1AS15_MOUSE B1AS15_MOUSE FIWNDDQNSSRHVIYIDQPT-LGMPSR-EYYFQEDNNHKVRKAYLEFMTSVATMLRKDQN B1AS16_MOUSE B1AS16_MOUSE FIWNDDQNSSRHVIYIDQPT-LGMPSR-EYYFQEDNNHKVRKAYLEFMTSVATMLRKDQN B1AS17_MOUSE B1AS17_MOUSE FIWNDDQNSSRHVIYIDQPT-LGMPSR-EYYFQEDNNHKVRKAYLEFMTSVATMLRKDQN B2RPX5_MOUSE B2RPX5_MOUSE FIWNDDQNSSRHVIYIDQPT-LGMPSR-EYYFQEDNNHKVRKAYLEFMTSVATMLRKDQN MMEL1_MOUSE MMEL1_MOUSE FIWNDDQNSSRHVIYIDQPT-LGMPSR-EYYFQEDNNHKVRKAYLEFMTSVATMLRKDQN Q4RX51_TETNG Q4RX51_TETNG YVWTDDRDSRQHIIYIDQPG-LGMPSR-DYYLNDGNYKKVREAYLQFMVSIAKITRDDRN B1WAX2_XENTR B1WAX2_XENTR FVWNDDRESSKHIIYIDQPS-LGMPSR-DYYFNKGNYQRIREAYLQFMITIARMVREDRN Q67BJ2_CHICK Q67BJ2_CHICK FVGTDDKNSTAHIIHIDQPG-LGLPSR-DYYECTGAYQEACSAYVDFMISVAKLILQERN NEP_RABIT NEP_RABIT FVGTDDKNSMNHIIHIDQPR-LGLPSR-DYYECTGIYKEACTAYVDFMIAVAKLIRQEEG NEP_PONAB NEP_PONAB FVGTDDKNSVNHVIHIDQPR-LGLPSR-DYYECTGIYKEACTAYVDFMISVARLIRQEER B7ZKY6_HUMAN B7ZKY6_HUMAN FVGTDDKNSVNHVIHIDQPR-LGLPSR-DYYECTGIYKEACTAYVDFMISVARLIRQEER NEP_HUMAN NEP_HUMAN FVGTDDKNSVNHVIHIDQPR-LGLPSR-DYYECTGIYKEACTAYVDFMISVARLIRQEER NEP_MOUSE NEP_MOUSE FVGTDDKNSTQHIIHFDQPR-LGLPSR-DYYECTGIYKEACTAYVDFMISVARLIRQEQS NEP_RAT NEP_RAT FVGTDDKNSTQHIIHFDQPR-LGLPSR-DYYECTGIYKEACTAYVDFMISVARLIRQEQR O93394_PERFV O93394_PERFV FVGTDDRDSNSYIIHFDQQTNLGLLSR-DYYACTGPYAEACRAYEKFMIDLAKLIRIDRG Q4SPQ9_TETNG Q4SPQ9_TETNG FIGIDDRDSSSHIIHYDQQGSLGLPSR-DQFACTGSSEALCKAYMHFMTELAKLIRTERG MATCH CONSENSUS ????D???S????I??DQ???L?LP?R??Y?????????????Y???M?????L??????

Q4RZ05_TETNG Q4RZ05_TETNG LGA---EAPTQKSKEIIELETRLANIT----VADYDDQRKDISTMYNRITLRQLQRMA-- Q5XHE7_XENLA Q5XHE7_XENLA LGV---ENVEKKAEEILHLEQHLSNIT----ISEFDDMRRDISTMYNKVTLAQLQQIT-- ECEL1_HUMAN ECEL1_HUMAN LGA---DAVEQKAQEILQVEQQLANIT----VSEHDDLRRDVSSMYNKVTLGQLQKIT-- ECEL1_RAT ECEL1_RAT LGA---DAVEQKAQEILQLEQRLANIS----VSEYDDLRRDVSSVYNKVTLGQLQKIT-- ECEL1_MOUSE ECEL1_MOUSE LGA---DAVEQKAQEILQLEQRLANIS----VSEYDDLRRDVSSAYNKVTLGQLQKII-- Q6PFG4_MOUSE Q6PFG4_MOUSE LGA---DAVEQKAQEILQLEQRLANIS----VSEYDDLRRDVSSAYNKVTLGQLQKII-- Q3TX93_MOUSE Q3TX93_MOUSE LGA---DAVEQKAQEILQLEQRLANIS----VSEYDDLRRDVSSAYNKVTLGQLQKII-- Q4SB05_TETNG Q4SB05_TETNG LGG-DQGSTRFQMQQILEFEKALASIT----VPQ--DQRRDEEKIYHKVSVSELQLLA-- B4DKF3_HUMAN B4DKF3_HUMAN LGG-RPTSTREQMQQVLELEIQLANIT----VPQ--DQRRDEEKIYHKMSISELQALA-- ECE2_BOVIN ECE2_BOVIN LGG-QPTSTREQMRQVLELEIQLANIT----VPQ--DQRRDEEKIYHKMSIAELQALA-- Q865C2_BOVIN Q865C2_BOVIN LGG-QPTSTREQMRQVLELEIQLANIT----VPQ--DQRRDEEKIYHKMSIAELQALA-- Q865C3_BOVIN Q865C3_BOVIN LGG-QPTSTREQMRQVLELEIQLANIT----VPQ--DQRRDEEKIYHKMSIAELQALA-- B4DF19_HUMAN B4DF19_HUMAN LGG-RPTSTREQMQQVLELEIQLANIT----VPQ--DQRRDEEKIYHKMSISELQALA-- ECE2_HUMAN ECE2_HUMAN LGG-RPTSTREQMQQVLELEIQLANIT----VPQ--DQRRDEEKIYHKMSISELQALA-- B4DHU4_HUMAN B4DHU4_HUMAN LGG-RPTSTREQMQQVLELEIQLANIT----VPQ--DQRRDEEKIYHKMSISELQALA-- Q6UW36_HUMAN Q6UW36_HUMAN LGG-RPTSTREQMQQVLELEIQLANIT----VPQ--DQRRDEEKIYHKMSISELQALA-- A5PLK8_HUMAN A5PLK8_HUMAN LGG-RPTSTREQMQQVLELEIQLANIT----VPQ--DQRRDEEKIYHKMSISELQALA-- Q8NFD7_HUMAN Q8NFD7_HUMAN LGG-RPTSTREQMQQVLELEIQLANIT----VPQ--DQRRDEEKIYHKMSISELQALA-- Q6IE65_RAT Q6IE65_RAT LGG-QPTSTRAQMQQVLELEIQLATIT----VPQ--DQRRDEEKIYHKMSISELQTLA-- ECE2_MOUSE ECE2_MOUSE LGG-QPTSTREQMQQVLELEIQLANIT----VPQ--DQRRDEEKIYHKMSISELQALA-- Q80Z57_MOUSE Q80Z57_MOUSE LGG-QPTSTREQMQQVLELEIQLANIT----VPQ--DQRRDEEKIYHKMSISELQALA-- Q80Z58_MOUSE Q80Z58_MOUSE LGG-QPTSTREQMQQVLELEIQLANIT----VPQ--DQRRDEEKIYHKMSISELQALA-- Q8K0P0_MOUSE Q8K0P0_MOUSE LGG-QPTSTREQMQQVLELEIQLANIT----VPQ--DQRRDEEKIYHKMSISELQALA-- Q8C099_MOUSE Q8C099_MOUSE LGG-QPTSTREQMQQVLELEIQLANIT----VPQ--DQRRDEEKIYHKMSISELQALA-- B2RQR8_MOUSE B2RQR8_MOUSE LGG-QPTSTREQMQQVLELEIQLANIT----VPQ--DQRRDEEKIYHKMSISELQALA-- Q923T6_MOUSE Q923T6_MOUSE LGG-QPTSTREQMQQVLELEIQLANIT----VPQ--DQRRDEEKIYHKMSISELQALA-- Q4T614_TETNG Q4T614_TETNG LGG-SAEASRTMMGAVVDFETALANIS----VPQ--EKRRDEELIYHKMEAKDLADLV-- A0JMP1_DANRE A0JMP1_DANRE LGG-SQDTSQKMMEEIIEFETTLANIT----VPQ--VERRDEEKIYYKIQAKELATLA-- A7LFV7_FUNHE A7LFV7_FUNHE LGG-SEETSRTVMTEIVDLETALANIT----VPQ--EERRDEELIYHKVQAKDLQDLA-- Q32NT6_XENLA Q32NT6_XENLA LGG-EENSTREQMQEILDFETKLANIT----IPQ--EKRRDEEQIYHKMTAGELKDLV-- B6RBR2_XENLA B6RBR2_XENLA LGG-EENSTRQQMQEILDFETKLANIT----IPQ--EKRRDEEQIYHKMTAGELKDLV-- Q7ZTK3_XENLA Q7ZTK3_XENLA LGG-EENSTRQQMQEILDFETKLANIT----IPQ--EKRRDEEQIYHKMTAGELKDLV-- Q9DGN6_CHICK Q9DGN6_CHICK LGGTDEESTRQQMQQILEFETALANIT----IPQ--EKHRDEEVIYHKMTAGELKDLA-- ECE1_CAVPO ECE1_CAVPO LGGGDENAIRAQMQQILDFETALANIT----IPQ--EKRRDEELIYHKVTAAELQTLA-- Q2Z2K8_HUMAN Q2Z2K8_HUMAN LGGGDEEAIRPQMQQILDFETALANIT----IPQ--EKRRDEELIYHKVTAAELQTLA-- B4DKB2_HUMAN B4DKB2_HUMAN LGGGDEEAIRPQMQQILDFETALANIT----IPQ--EKRRDEELIYHKVTAAELQTLA-- ECE1_HUMAN ECE1_HUMAN LGGGDEEAIRPQMQQILDFETALANIT----IPQ--EKRRDEELIYHKVTAAELQTLA-- ECE1_RAT ECE1_RAT LGGGDEDSIRPQMQQILDFETALANIT----IPQ--EKRRDEELIYHKVTAAELQTLA-- ECE1_MOUSE ECE1_MOUSE LGGGDEDAIRPQMQQILDFETALANIT----IPQ--EKRRDEELIYHKVTAAELQTLA-- Q6IN10_RAT Q6IN10_RAT LGGGDEDSIRPQMQQILDFETALANIT----IPQ--EKRRDEELIYHKVTAAELQTLA-- Q3HTT4_CANFA Q3HTT4_CANFA LGGGDEDAIRPQMQQILDFETALANIT----IPQ--EKRRDEELIYHKVTAAELQALA-- ECE1_BOVIN ECE1_BOVIN LGGGAEDTIRPQMQQILDFETALANIT----IPQ--EKRRDEELIYHKVTAAELQTLA-- Q28010_BOVIN Q28010_BOVIN LGGGAEDTIRPQMQQILDFETALANIT----IPQ--EKRRDEELIYHKVTAAELQTLA-- Q28868_BOVIN Q28868_BOVIN LGGGAEDTIRPQMQQILDFETALANIT----IPQ--EKRRDEELIYHKVTAAELQTLA-- O35812_RAT O35812_RAT LGA-NSSRAEHDMKSVLRLEIKIAEIM----IPH---ENRTSEAMYNKMNISELSAMI-- A2ICR0_MOUSE A2ICR0_MOUSE LGA-NSSRAEHDMKSVLRLEIKIAEIM----IPH---ENRTSEAMYNKMNISELSAMI-- Q3TYM9_MOUSE Q3TYM9_MOUSE LGA-NSSRAEHDMKSVLRLEIKIAEIM----IPH---ENRTSEAMYNKMNISELSAMI-- PHEX_MOUSE PHEX_MOUSE LGA-NSSRAEHDMKSVLRLEIKIAEIM----IPH---ENRTSEAMYNKMNISELSAMI-- A2AC80_MOUSE A2AC80_MOUSE LGA-NSSRAEHDMKSVLRLEIKIAEIM----IPH---ENRTSEAMYNKMNISELSAMI-- B4E334_HUMAN B4E334_HUMAN --------------KVLGLQ---------------------------------------- B4DNS0_HUMAN B4DNS0_HUMAN LGA-NSSRAEHDMKSVLRLEIKIAEIM----IPH---ENRTSEAMYNKMNISELSAMI-- B4DWG8_HUMAN B4DWG8_HUMAN LGA-NSSRAEHDMKSVLRLEIKIAEIM----IPH---ENRTSEAMYNKMNISELSAMI-- PHEX_HUMAN PHEX_HUMAN LGA-NSSRAEHDMKSVLRLEIKIAEIM----IPH---ENRTSEAMYNKMNISELSAMI-- A4QP66_DANRE A4QP66_DANRE LGA-SEQAAEAQMKSVLDFEMKLAQIV----IPY---ENRTSENMYNKYSLSKLQRTV-- Q4S1N5_TETNG Q4S1N5_TETNG LGA-PEKAAQAQMEQALAFETKIAHIL----VPY---ENRTSENMYNRYSISRLHRHI-- B9DI79_HUMAN B9DI79_HUMAN LPR-DSCLVQEDMVQVLELETQLAKAT----VPQ--EERHDVIALYHRMGLEELQSQFGL MMEL1_HUMAN MMEL1_HUMAN LPR-DSCLVQEDMVQVLELETQLAKAT----VPQ--EERHDVIALYHRMGLEELQSQFGL B3KS82_HUMAN B3KS82_HUMAN LPR-DSCLVQEDMVQVLELETQLAKAT----VPQ--EERHDVIALYHRMGLEELQSQFGL MMEL1_RAT MMEL1_RAT LPG-ETDLVQEEMAQVLHLETHLANAT----VPQ--EKRHDVTALYHRMGLEELQERFGL B1AS15_MOUSE B1AS15_MOUSE LSK-ESAMVREEMAEVLELETHLANAT----VPQ--EKRHDVTALYHRMDLMELQERFGL B1AS16_MOUSE B1AS16_MOUSE LSK-ESAMVREEMAEVLELETHLANAT----VPQ--EKRHDVTALYHRMDLMELQERFGL B1AS17_MOUSE B1AS17_MOUSE LSK-ESAMVREEMAEVLELETHLANAT----VPQ--EKRHDVTALYHRMDLMELQERFGL B2RPX5_MOUSE B2RPX5_MOUSE LSK-ESAMVREEMAEVLELETHLANAT----VPQ--EKRHDVTALYHRMDLMELQERFGL MMEL1_MOUSE MMEL1_MOUSE LSK-ESAMVREEMAEVLELETHLANAT----VPQ--EKRHDVTALYHRMDLMELQERFGL Q4RX51_TETNG Q4RX51_TETNG LTQ-DDDRLWEEMMQVLELETDIANAT----SPA--EERQDVTVLYNKMTIAELQNTFSF B1WAX2_XENTR B1WAX2_XENTR LTR-DDSLVQEEMTRVMDLETDIARAT----APS--EERNDVTLLYNKMTLLEFQQKFAL Q67BJ2_CHICK Q67BJ2_CHICK ITF-NETQIAEEMKRVMDLEKEIANAT----TKS--EDRNDPLLLYNKMTLAQLQNNFSL NEP_RABIT NEP_RABIT LPI-DENQISVEMNKVMELEKEIANAT----TKS--EDRNDPMLLYNKMTLAQIQNNFSL NEP_PONAB NEP_PONAB LPI-DENQLALEMNKVMELEKEIANAT----AKP--EDRNDPMLLYKKMTLAQIQNNFSL B7ZKY6_HUMAN B7ZKY6_HUMAN LPI-DENQLALEMNKVMELEKEIANAT----AKP--EDRNDPMLLYNKMTLAQIQNNFSL NEP_HUMAN NEP_HUMAN LPI-DENQLALEMNKVMELEKEIANAT----AKP--EDRNDPMLLYNKMTLAQIQNNFSL NEP_MOUSE NEP_MOUSE LPI-DENQLSLEMNKVMELEKEIANAT----TKP--EDRNDPMLLYNKMTLAKLQNNFSL NEP_RAT NEP_RAT LPI-DENQLSLEMNKVMELEKEIANAT----TKP--EDRNDPMLLYNKMTLAKLQNNFSL O93394_PERFV O93394_PERFV LNI-SETDIREEVKRVMDLERDIANAT----DTP--EDRNNPVLLYNKMELGDLNANFTL Q4SPQ9_TETNG Q4SPQ9_TETNG LAI-NETQINQEVIRILEFESDLANVRHFSFDTQ--EDRSNPGFLYNKMELGDLNANFTI MATCH : .: CONSENSUS L???????????M???L??E???A??????????????R?D????Y?K?????L??????

Q4RZ05_TETNG Q4RZ05_TETNG -----------------------------------PS----------LHWKRLLDRI--- Q5XHE7_XENLA Q5XHE7_XENLA -----------------------------------PH----------LSWKNLLDRI--- ECEL1_HUMAN ECEL1_HUMAN -----------------------------------PH----------LRWKWLLDQI--- ECEL1_RAT ECEL1_RAT -----------------------------------PH----------LQWKWLLDQI--- ECEL1_MOUSE ECEL1_MOUSE -----------------------------------PH----------LQWKWLLDQI--- Q6PFG4_MOUSE Q6PFG4_MOUSE -----------------------------------PH----------LQWKWLLDQI--- Q3TX93_MOUSE Q3TX93_MOUSE -----------------------------------PH----------LQWKWLLDQI--- Q4SB05_TETNG Q4SB05_TETNG -----------------------------------PA----------VDWLDYLSSS--- B4DKF3_HUMAN B4DKF3_HUMAN -----------------------------------PS----------MDWLEFLSFL--- ECE2_BOVIN ECE2_BOVIN -----------------------------------PS----------MDWLEFLSFL--- Q865C2_BOVIN Q865C2_BOVIN -----------------------------------PS----------MDWLEFLSFL--- Q865C3_BOVIN Q865C3_BOVIN -----------------------------------PS----------MDWLEFLSFL--- B4DF19_HUMAN B4DF19_HUMAN -----------------------------------PS----------MDWLEFLSFL--- ECE2_HUMAN ECE2_HUMAN -----------------------------------PS----------MDWLEFLSFL--- B4DHU4_HUMAN B4DHU4_HUMAN -----------------------------------PS----------MDWLEFLSFL--- Q6UW36_HUMAN Q6UW36_HUMAN -----------------------------------PS----------MDWLEFLSFL--- A5PLK8_HUMAN A5PLK8_HUMAN -----------------------------------PS----------MDWLEFLSSL--- Q8NFD7_HUMAN Q8NFD7_HUMAN -----------------------------------PS----------MDWLEFLSFL--- Q6IE65_RAT Q6IE65_RAT -----------------------------------PS----------MDWLEFLSFL--- ECE2_MOUSE ECE2_MOUSE -----------------------------------PA----------VDWLEFLSFL--- Q80Z57_MOUSE Q80Z57_MOUSE -----------------------------------PA----------VDWLEFLSFL--- Q80Z58_MOUSE Q80Z58_MOUSE -----------------------------------PA----------VDWLEFLSFL--- Q8K0P0_MOUSE Q8K0P0_MOUSE -----------------------------------PA----------VDWLEFLSFL--- Q8C099_MOUSE Q8C099_MOUSE -----------------------------------PA----------VDWLEFLSFL--- B2RQR8_MOUSE B2RQR8_MOUSE -----------------------------------PA----------VDWLEFLSFL--- Q923T6_MOUSE Q923T6_MOUSE -----------------------------------PA----------VDWLEFLSFL--- Q4T614_TETNG Q4T614_TETNG -----------------------------------PV----------VDWMPYLTAV--- A0JMP1_DANRE A0JMP1_DANRE -----------------------------------PA----------IDWMPFLSSV--- A7LFV7_FUNHE A7LFV7_FUNHE -----------------------------------PA----------VDWMPYLKEV--- Q32NT6_XENLA Q32NT6_XENLA -----------------------------------PA----------VDWMPFLKTV--- B6RBR2_XENLA B6RBR2_XENLA -----------------------------------PA----------VDWMPFLKTV--- Q7ZTK3_XENLA Q7ZTK3_XENLA -----------------------------------PA----------VDWMPFLKTV--- Q9DGN6_CHICK Q9DGN6_CHICK -----------------------------------PA----------VDWMPFLSTV--- ECE1_CAVPO ECE1_CAVPO -----------------------------------PA----------INWLPFLNTI--- Q2Z2K8_HUMAN Q2Z2K8_HUMAN -----------------------------------PA----------INWLPFLNTI--- B4DKB2_HUMAN B4DKB2_HUMAN -----------------------------------PA----------INWLPFLNTI--- ECE1_HUMAN ECE1_HUMAN -----------------------------------PA----------INWLPFLNTI--- ECE1_RAT ECE1_RAT -----------------------------------PA----------INWLPFLNAI--- ECE1_MOUSE ECE1_MOUSE -----------------------------------PA----------INWLPFLNTI--- Q6IN10_RAT Q6IN10_RAT -----------------------------------PA----------INWLPFLNAI--- Q3HTT4_CANFA Q3HTT4_CANFA -----------------------------------PA----------IDWLPFLNTI--- ECE1_BOVIN ECE1_BOVIN -----------------------------------PA----------INWLPFLNTI--- Q28010_BOVIN Q28010_BOVIN -----------------------------------PA----------INWLPFLNTI--- Q28868_BOVIN Q28868_BOVIN -----------------------------------PA----------INWLPFLNTI--- O35812_RAT O35812_RAT -----------------------------------PQ----------FDWLGYIKKVIDT A2ICR0_MOUSE A2ICR0_MOUSE -----------------------------------PQ----------FDWLGYIKKVIDT Q3TYM9_MOUSE Q3TYM9_MOUSE -----------------------------------PQ----------FDWLGYIKKVIDT PHEX_MOUSE PHEX_MOUSE -----------------------------------PQ----------FDWLGYIKKVIDT A2AC80_MOUSE A2AC80_MOUSE -----------------------------------PQ----------FDWLGYIKKVIDT B4E334_HUMAN B4E334_HUMAN -----------------------------------------------FDWLGYIKKVIDT B4DNS0_HUMAN B4DNS0_HUMAN -----------------------------------PQ----------FDWLGYIKKVIDT B4DWG8_HUMAN B4DWG8_HUMAN -----------------------------------PQ----------FDWLGYIKKVIDT PHEX_HUMAN PHEX_HUMAN -----------------------------------PQ----------FDWLGYIKKVIDT A4QP66_DANRE A4QP66_DANRE -----------------------------------PD----------FNWLGFVRAVIDT Q4S1N5_TETNG Q4S1N5_TETNG -----------------------------------PE----------FDWLGFIKRVVET B9DI79_HUMAN B9DI79_HUMAN -----------------------------------KG----------FNWTLFIQTV--- MMEL1_HUMAN MMEL1_HUMAN -----------------------------------KG----------FNWTLFIQTV--- B3KS82_HUMAN B3KS82_HUMAN -----------------------------------KG----------FNWTLFIQTV--- MMEL1_RAT MMEL1_RAT -----------------------------------KG----------FNWTLFIQNV--- B1AS15_MOUSE B1AS15_MOUSE -----------------------------------KG----------FNWTLFIQNV--- B1AS16_MOUSE B1AS16_MOUSE -----------------------------------KG----------FNWTLFIQNV--- B1AS17_MOUSE B1AS17_MOUSE KDRVSLCSPGCPGTHSVDQAGLKLRNP--------PASDSRVLGLKGFNWTLFIQNV--- B2RPX5_MOUSE B2RPX5_MOUSE -----------------------------------KG----------FNWTLFIQNV--- MMEL1_MOUSE MMEL1_MOUSE -----------------------------------KG----------FNWTLFIQNV--- Q4RX51_TETNG Q4RX51_TETNG -----------------------------------NG----------FNWTRFIQGV--- B1WAX2_XENTR B1WAX2_XENTR -----------------------------------DD----------FNWTSFIQGV--- Q67BJ2_CHICK Q67BJ2_CHICK EINH-------------------------------MA----------FNWSKFINNI--- NEP_RABIT NEP_RABIT EING-------------------------------KP----------FSWSNFTNEI--- NEP_PONAB NEP_PONAB EING-------------------------------KP----------FSWLNFTNEI--- B7ZKY6_HUMAN B7ZKY6_HUMAN EING-------------------------------KP----------FSWLNFTNEI--- NEP_HUMAN NEP_HUMAN EING-------------------------------KP----------FSWLNFTNEI--- NEP_MOUSE NEP_MOUSE EVNG-------------------------------KS----------FSWSNFTNEI--- NEP_RAT NEP_RAT EING-------------------------------KP----------FSWSNFTNEI--- O93394_PERFV O93394_PERFV EVES-------------------------------QV----------FDWSYFTAKI--- Q4SPQ9_TETNG Q4SPQ9_TETNG EVDSQVIDTYSSVKISVFFTSPCLLLLWFCLPTLPQV----------FNWTYFTANI--- MATCH . * CONSENSUS ?????????????????????????????????????????????????W??????????

Q4RZ05_TETNG Q4RZ05_TETNG -FHD---TFSDDEEIVVLATDYIQKVSDIIKTTSKRVLHNYMLWRIVAALSEHLSTAFRS Q5XHE7_XENLA Q5XHE7_XENLA -FHT---NFPEDEEVVVLASDYMQKVSEMIRATPASVLHNYMLWRIVVVLSEHLSTPFRD ECEL1_HUMAN ECEL1_HUMAN -FQE---DFSEEEEVVLLATDYMQQVSQLIRSTPHRVLHNYLVWRVVVVLSEHLSPPFRE ECEL1_RAT ECEL1_RAT -FQE---DFSEEEEVVLLATDYMQQVSQLIRSTPRRILHNYLVWRVVVVLSEHLSPPFRE ECEL1_MOUSE ECEL1_MOUSE -FQE---DFSEEEEVVLLATDYMQQVSQLIRSTPRRILHNYLVWRVVVVLSEHLSSPFRE Q6PFG4_MOUSE Q6PFG4_MOUSE -FQE---DFSEEEEVVLLATDYMQQVSQLIRSTPRRILHNYLVWRVVVVLSEHLSSPFRE Q3TX93_MOUSE Q3TX93_MOUSE -FQE---DFSEEEEVVLLATDYMQQVSQLIRSTPRRILHNYLVWRVVVVLSEHLSSPFRE Q4SB05_TETNG Q4SB05_TETNG -LSP--LDLNDTEPVVLYTREYLQQVSDLINKTDRSLVNNYMIWTLVQKTVTSLDQRFEN B4DKF3_HUMAN B4DKF3_HUMAN -LSP--LELSDSEPVVVYGMDYLQQVSELINRTEPSILNNYLIWNLVQKTTSSLDRRFES ECE2_BOVIN ECE2_BOVIN -LSP--LELGDSEPVVVYGTDYLQQVSELINRTEPSVLNNYLIWNLVQKTTSSLDHRFES Q865C2_BOVIN Q865C2_BOVIN -LSP--LELGDSEPVVVYGTDYLQQVSELINRTEPSVLNNYLIWNLVQKTTSSLDHRFES Q865C3_BOVIN Q865C3_BOVIN -LSP--LELGDSEPVVVYGTDYLQQVSELINRTEPSVLNNYLIWNLVQKTTSSLDHRFES B4DF19_HUMAN B4DF19_HUMAN -LSP--LELSDSEPVVVYGMDYLQQVSELINRTEPSILNNYLIWNLVQKTTSSLDRRFES ECE2_HUMAN ECE2_HUMAN -LSP--LELSDSEPVVVYGMDYLQQVSELINRTEPSILNNYLIWNLVQKTTSSLDRRFES B4DHU4_HUMAN B4DHU4_HUMAN -LSP--LELSDSEPVVVYGMDYLQQVSELINRTEPSILNNYLIWNLVQKTTSSLDRRFES Q6UW36_HUMAN Q6UW36_HUMAN -LSP--LELSDSEPVVVYGMDYLQQVSELINRTEPSILNNYLIWNLVQKTTSSLDRRFES A5PLK8_HUMAN A5PLK8_HUMAN -LSP--LELSDSEPVVVYGMDYLQQVSELINRTEPSILNNYLIWNLVQKTTSSLDRRFES Q8NFD7_HUMAN Q8NFD7_HUMAN -LSP--LELSDSEPVVVYGMDYLQQVSELINRTEPSILNNYLIWNLVQKTTSSLDRRFES Q6IE65_RAT Q6IE65_RAT -LSP--LELGDSEPVVVYGTEYLQQVSELINRTEPSILNNYLIWNLVQKTTSSLDQRFET ECE2_MOUSE ECE2_MOUSE -LSP--LELGDSEPVVVYGMSYLQQVSELINRTEPSILNNYLIWNLVQKTTSSLDQRFET Q80Z57_MOUSE Q80Z57_MOUSE -LSP--LELGDSEPVVVYGMSYLQQVSELINRTEPSILNNYLIWNLVQKTTSSLDQRFET Q80Z58_MOUSE Q80Z58_MOUSE -LSP--LELGDSEPVVVYGMSYLQQVSELINRTEPSILNNYLIWNLVQKTTSSLDQRFET Q8K0P0_MOUSE Q8K0P0_MOUSE -LSP--LELGDSEPVVVYGTEYLQQVSELINRTEPSILNNYLIWNLVQKTTSSLDQRFET Q8C099_MOUSE Q8C099_MOUSE -LSP--LELGDSEPVVVYGTEYLQQVSELINRTEPSILNNYLIWNLVQKTTSSLDQRFET B2RQR8_MOUSE B2RQR8_MOUSE -LSP--LELGDSEPVVVYGTEYLQQVSELINRTEPSILNNYLIWNLVQKTTSSLDQRFET Q923T6_MOUSE Q923T6_MOUSE -LSP--LELGDSEPVVVYGTEYLQQVSELINRTEPSILNNYLIWNLVQKTTSSLDQRFET Q4T614_TETNG Q4T614_TETNG -FAP--VALNESEPVVVYAREYLRDVSELINRTDKSLLNNYMIMKVVRKMVSVLDQRFQD A0JMP1_DANRE A0JMP1_DANRE -FAP--VELNNSEPVVVYAKEYLQKVSELISNTNKSVLNNYMIMKVVRKMVSILDQKFQD A7LFV7_FUNHE A7LFV7_FUNHE -FTP--VTLSESEPVVVYAKEYLQKVSELITNTNKSLLNNYMIMKVVRKMVSVLDQRFQD Q32NT6_XENLA Q32NT6_XENLA -FHP--VVINESEPVVVYAKEYLVEVSSLINSTDKRILNNYMMWNLMRKTSSFLDQRFQD B6RBR2_XENLA B6RBR2_XENLA -FHP--VVINESEPVVVYAKEYLVEVSSLINSTDKRILNNYMMWNLMRKTSSFLDQRFQD Q7ZTK3_XENLA Q7ZTK3_XENLA -FHP--VVINESEPVVVYAKEYLVEVSSLINSTDKRILNNYMMWNLMRKTSSFLDQRFQD Q9DGN6_CHICK Q9DGN6_CHICK -FYP--VELNESEPVVVYAKEYLEQVSDLILATDKCLLNNYMIWNLVRKTSPFLDQRFQD ECE1_CAVPO ECE1_CAVPO -FYP--VEINESEPIVVYDKEYLEQVSTLINTTDKCLLNNYMIWNLVRKTSSFLDQRFQD Q2Z2K8_HUMAN Q2Z2K8_HUMAN -FYP--VEINESEPIVVYDKEYLEQISTLINTTDRCLLNNYMIWNLVRKTSSFLDQRFQD B4DKB2_HUMAN B4DKB2_HUMAN -FYP--VEINESEPIVVYDKEYLEQISTLINTTDRCLLNNYMIWNLVRKTSSFLDQRFQD ECE1_HUMAN ECE1_HUMAN -FYP--VEINESEPIVVYDKEYLEQISTLINTTDRCLLNNYMIWNLVRKTSSFLDQRFQD ECE1_RAT ECE1_RAT -FYP--VEINESEPIVVYDKEYLRQVSTLINSTDKCLLNNYMMWNLVRKTSSFLDQRFQD ECE1_MOUSE ECE1_MOUSE -FYP--VEINESEPIVVYDKEYLRQVSTLINNTDKCLLNNYMMWNLVRKTSSFLDQRFQD Q6IN10_RAT Q6IN10_RAT -FYP--VEINESEPIVVYDKEYLRQVSTLINSTDKCLLNNYMMWNLVRKTSSFLDQRFQD Q3HTT4_CANFA Q3HTT4_CANFA -FYP--VEINESEPIVVYDKEYLGQVSTLINNTDKCLLNNYMIWNLVRKTSSFLDQRFQD ECE1_BOVIN ECE1_BOVIN -FYP--VEINESEPIVIYDKEYLSKVSTLINSTDKCLLNNYMIWNLVRKTSSFLDQRFQD Q28010_BOVIN Q28010_BOVIN -FYP--VEINESEPIVIYDKEYLSKVSTLINSTDKCLLNNYMIWNLVRKTSSFLDQRFQD Q28868_BOVIN Q28868_BOVIN -FYP--VEINESEPIVIYDKEYLSKVSTLINSTDKCLLNNYMIWNLVRKTSSFLDQRFQD O35812_RAT O35812_RAT RLYPHLKDIGPSENVVVRVPQYFKDLFRILGAERKKTIANYLVWRMVYSRIPNLSRRFQY A2ICR0_MOUSE A2ICR0_MOUSE RLYPHLKDIGPSENVVVRVPQYFKDLFRILGAERKKTIANYLVWRMVYSRIPNLSRRFQY Q3TYM9_MOUSE Q3TYM9_MOUSE RLYPHLKDIGPSENVVVRVPQYFKDLFRILGAERKKTIANYLVWRMVYSRIPNLSRRFQY PHEX_MOUSE PHEX_MOUSE RLYPHLKDIGPSENVVVRVPQYFKDLFRILGAERKKTIANYLVWRMVYSRIPNLSRRFQY A2AC80_MOUSE A2AC80_MOUSE RLYPHLKDIGPSENVVVRVPQYFKDLFRILGAERKKTIANYLVWRMVYSRIPNLSRRFQY B4E334_HUMAN B4E334_HUMAN RLYPHLKDISPSENVVVRVPQYFKDLFRILGSERKKTIANYLVWRMVYSRIPNLSRRFQY B4DNS0_HUMAN B4DNS0_HUMAN RLYPHLKDISPSENVVVRVPQYFKDLFRILGSERKKTIANYLVWRMVYSRIPNLSRRFQY B4DWG8_HUMAN B4DWG8_HUMAN RLYPHLKDISPSENVVVRVPQYFKDLFRILGSERKKTIANYLVWRMVYSRIPNLSRRFQY PHEX_HUMAN PHEX_HUMAN RLYPHLKDISPSENVVVRVPQYFKDLFRILGSERKKTIANYLVWRMVYSRIPNLSRRFQY A4QP66_DANRE A4QP66_DANRE ELYP-DLKISSSEQVIVRAPQYFKDLFKLINATDTRTVANYVIWRSVFSRITTLSRRFLY Q4S1N5_TETNG Q4S1N5_TETNG -KEDKSRSISSSEHVIVRVPQYFKDLFKLINSTDPRIVANYVQWRTVFSRITSLSRRFLY B9DI79_HUMAN B9DI79_HUMAN -LSSVKIKLLPDEEVVVYGIPYLQNLENIIDTYSARTIQNYLVWRLVLDRIGSLSQRFKD MMEL1_HUMAN MMEL1_HUMAN -LSSVKIKLLPDEEVVVYGIPYLQNLENIIDTYSARTIQNYLVWRLVLDRIGSLSQRFKD B3KS82_HUMAN B3KS82_HUMAN -LSSVKIKLLPDEEVVVYGIPYLQNLENIIDTYSARTIQNYLVWRLVLDRIGSLSQRFKD MMEL1_RAT MMEL1_RAT -LSSVQVELLPNEEVVVYGIPYLENLEEIIDVFPAQTLQNYLVWRLVLDRIGSLSQRFKE B1AS15_MOUSE B1AS15_MOUSE -LSSVEVELFPDEEVVVYGIPYLENLEDIIDSYSARTMQNYLVWRLVLDRIGSLSQRFKE B1AS16_MOUSE B1AS16_MOUSE -LSSVEVELFPDEEVVVYGIPYLENLEDIIDSYSARTMQNYLVWRLVLDRIGSLSQRFKE B1AS17_MOUSE B1AS17_MOUSE -LSSVEVELFPDEEVVVYGIPYLENLEDIIDSYSARTMQNYLVWRLVLDRIGSLSQRFKE B2RPX5_MOUSE B2RPX5_MOUSE -LSSVEVELFPDEEVVVYGIPYLENLEDIIDSYSARTMQNYLVWRLVLDRIGSLSQRFKE MMEL1_MOUSE MMEL1_MOUSE -LSSVEVELFPDEEVVVYGIPYLENLEDIIDSYSARTMQNYLVWRLVLDRIGSLSQRFKE Q4RX51_TETNG Q4RX51_TETNG -LSSVSIQVLLEEEVVVYSSPYLEKMNEVLPKHSVRTMQNYLMWQLIIDRVNSLSRRFKD B1WAX2_XENTR B1WAX2_XENTR -MSSVNIQLQAEEEVVVYGAPYLHQLKNILSNYSASTLQNYVVWRMVIDRVSSLSRRYKD Q67BJ2_CHICK Q67BJ2_CHICK -MSTVQIDVENTEHVVVYDPEYLTKLKSILNKYTPRELQNYMIWRFVMDLVNSLSRNYKD NEP_RABIT NEP_RABIT -MSTVNINIPNEEDVVVYAPEYLIKLKPILTKYFPRDFQNLFSWRFIMDLVSSLSRTYKD NEP_PONAB NEP_PONAB -MSTVNISITNEEDVVVYAPEYLTKLKPILTKYSARDLQNLMSWRFIMDLVSSLSRTYKE B7ZKY6_HUMAN B7ZKY6_HUMAN -MSTVNISITNEEDVVVYAPEYLTKLKPILTKYSARDLQNLMSWRFIMDLVSSLSRTYKE NEP_HUMAN NEP_HUMAN -MSTVNISITNEEDVVVYAPEYLTKLKPILTKYSARDLQNLMSWRFIMDLVSSLSRTYKE NEP_MOUSE NEP_MOUSE -MSTVNINIQNEEEVVVYAPEYLTKLKPILTKYSPRDLQNLMSWRFIMDLVSSLSRNYKE NEP_RAT NEP_RAT -MSTVNINIQNEEEVVVYAPEYLTKLKPILTKYSPRDLQNLMSWRFIMDLVSSLSRNYKE O93394_PERFV O93394_PERFV -MDTVNISVPDTEKVINYSPNYYRRLNLILARYNKRDLQNYMVWRFAMNMVVGLSRSYRD Q4SPQ9_TETNG Q4SPQ9_TETNG -MDTVNISIPETEKIMIYAPNYFRRLNHTLAKYTKRDLQNYMVWRFVMSMVSSLSGSYKD MATCH . * :: * : : . * . *. : CONSENSUS ????????????E?VVV????Y?????????????????NY??W??V??????L???F??

Q4RZ05_TETNG Q4RZ05_TETNG TIHEFSR----------------------EIDGT-------------------------- Q5XHE7_XENLA Q5XHE7_XENLA AIHELSK----------------------EMEGS-------------------------- ECEL1_HUMAN ECEL1_HUMAN ALHELAQ----------------------EMEGS-------------------------- ECEL1_RAT ECEL1_RAT ALHELAK----------------------EMEGN-------------------------- ECEL1_MOUSE ECEL1_MOUSE ALHELAK----------------------EMEGN-------------------------- Q6PFG4_MOUSE Q6PFG4_MOUSE ALHELAK----------------------EMEGN-------------------------- Q3TX93_MOUSE Q3TX93_MOUSE ALHELAK----------------------EMEGN-------------------------- Q4SB05_TETNG Q4SB05_TETNG AQDKLLE----------------------SLIGTK------------------------- B4DKF3_HUMAN B4DKF3_HUMAN AQEKLLE----------------------TLYGTK------------------------- ECE2_BOVIN ECE2_BOVIN AQEKLLE----------------------TLYGTK------------------------- Q865C2_BOVIN Q865C2_BOVIN AQEKLLE----------------------TLYGTK------------------------- Q865C3_BOVIN Q865C3_BOVIN AQEKLLE----------------------TLYGTK------------------------- B4DF19_HUMAN B4DF19_HUMAN AQEKLLE----------------------TLYGTK------------------------- ECE2_HUMAN ECE2_HUMAN AQEKLLE----------------------TLYGTK------------------------- B4DHU4_HUMAN B4DHU4_HUMAN AQEKLLE----------------------TLYGTK------------------------- Q6UW36_HUMAN Q6UW36_HUMAN AQEKLLE----------------------TLYGTK------------------------- A5PLK8_HUMAN A5PLK8_HUMAN AQEKLLE----------------------TLYGTK------------------------- Q8NFD7_HUMAN Q8NFD7_HUMAN AQEKLLE----------------------TLYGTK------------------------- Q6IE65_RAT Q6IE65_RAT AQEKLLE----------------------TLYGTK------------------------- ECE2_MOUSE ECE2_MOUSE AQEKLLE----------------------TLYGTK------------------------- Q80Z57_MOUSE Q80Z57_MOUSE AQEKLLE----------------------TLYGTK------------------------- Q80Z58_MOUSE Q80Z58_MOUSE AQEKLLE----------------------TLYGTK------------------------- Q8K0P0_MOUSE Q8K0P0_MOUSE AQEKLLE----------------------TLYGTK------------------------- Q8C099_MOUSE Q8C099_MOUSE AQEKLLE----------------------TLYGTK------------------------- B2RQR8_MOUSE B2RQR8_MOUSE AQEKLLE----------------------TLYGTK------------------------- Q923T6_MOUSE Q923T6_MOUSE AQEKLLE----------------------TLYGTK------------------------- Q4T614_TETNG Q4T614_TETNG AEQRFLE----------------------VMYGTKKLESGVSAGLDLGILHILALLFALE A0JMP1_DANRE A0JMP1_DANRE AEQRFLE----------------------VMYGTK------------------------- A7LFV7_FUNHE A7LFV7_FUNHE AEQRFLE----------------------VMYGTK------------------------- Q32NT6_XENLA Q32NT6_XENLA AEEKLIE----------------------VMYGTK------------------------- B6RBR2_XENLA B6RBR2_XENLA AEEKLIE----------------------VMYGTK------------------------- Q7ZTK3_XENLA Q7ZTK3_XENLA AEEKLIE----------------------VMYGTK------------------------- Q9DGN6_CHICK Q9DGN6_CHICK AEEKFME----------------------VMYGTK------------------------- ECE1_CAVPO ECE1_CAVPO ADEKFME----------------------VMYGTK------------------------- Q2Z2K8_HUMAN Q2Z2K8_HUMAN ADEKFME----------------------VMYGTK------------------------- B4DKB2_HUMAN B4DKB2_HUMAN ADEKFME----------------------VMYGTK------------------------- ECE1_HUMAN ECE1_HUMAN ADEKFME----------------------VMYGTK------------------------- ECE1_RAT ECE1_RAT ADEKFME----------------------VMYGTK------------------------- ECE1_MOUSE ECE1_MOUSE ADEKFME----------------------VMYGTK------------------------- Q6IN10_RAT Q6IN10_RAT ADEKFME----------------------VMYGTK------------------------- Q3HTT4_CANFA Q3HTT4_CANFA ADEKFME----------------------VMYGTK------------------------- ECE1_BOVIN ECE1_BOVIN ADEKFME----------------------VMYGTK------------------------- Q28010_BOVIN Q28010_BOVIN ADEKFME----------------------VMYGTK------------------------- Q28868_BOVIN Q28868_BOVIN ADEKFME----------------------VMYGTK------------------------- O35812_RAT O35812_RAT RWLEFSR----------------------VIQGT-------------------------- A2ICR0_MOUSE A2ICR0_MOUSE RWLEFSR----------------------VIQGT-------------------------- Q3TYM9_MOUSE Q3TYM9_MOUSE RWLEFSR----------------------VIQGT-------------------------- PHEX_MOUSE PHEX_MOUSE RWLEFSR----------------------VIQGT-------------------------- A2AC80_MOUSE A2AC80_MOUSE RWLEFSR----------------------VIQGT-------------------------- B4E334_HUMAN B4E334_HUMAN RWLEFSR----------------------VIQGT-------------------------- B4DNS0_HUMAN B4DNS0_HUMAN RWLEFSR----------------------VIQGT-------------------------- B4DWG8_HUMAN B4DWG8_HUMAN RWLEFSR----------------------VIQGT-------------------------- PHEX_HUMAN PHEX_HUMAN RWLEFSR----------------------VIQGT-------------------------- A4QP66_DANRE A4QP66_DANRE RYLDFAR----------------------VTTGT-------------------------- Q4S1N5_TETNG Q4S1N5_TETNG RYLDFAR----------------------VTTGT-------------------------- B9DI79_HUMAN B9DI79_HUMAN TRVNYRK----------------------ALFGT-------------------------- MMEL1_HUMAN MMEL1_HUMAN TRVNYRK----------------------ALFGT-------------------------- B3KS82_HUMAN B3KS82_HUMAN TRVNYRK----------------------ALFGT-------------------------- MMEL1_RAT MMEL1_RAT ARVDYRK----------------------ALYGT-------------------------- B1AS15_MOUSE B1AS15_MOUSE ARVDYRK----------------------ALYGT-------------------------- B1AS16_MOUSE B1AS16_MOUSE ARVDYRK----------------------ALYGT-------------------------- B1AS17_MOUSE B1AS17_MOUSE ARVDYRK----------------------ALYGT-------------------------- B2RPX5_MOUSE B2RPX5_MOUSE ARVDYRK----------------------ALYGT-------------------------- MMEL1_MOUSE MMEL1_MOUSE ARVDYRK----------------------ALYGT-------------------------- Q4RX51_TETNG Q4RX51_TETNG ARTRYRKVHYSRRCLSQSARYIINNSCLQTLYGT-------------------------- B1WAX2_XENTR B1WAX2_XENTR ARASYRK----------------------ALYGT-------------------------- Q67BJ2_CHICK Q67BJ2_CHICK TRNAFRK----------------------ALYGT-------------------------- NEP_RABIT NEP_RABIT SRNAFRK----------------------ALYGT-------------------------- NEP_PONAB NEP_PONAB SRNAFRK----------------------ALYGT-------------------------- B7ZKY6_HUMAN B7ZKY6_HUMAN SRNAFRK----------------------ALYGT-------------------------- NEP_HUMAN NEP_HUMAN SRNAFRK----------------------ALYGT-------------------------- NEP_MOUSE NEP_MOUSE SRNAFRK----------------------ALYGT-------------------------- NEP_RAT NEP_RAT SRNAFRK----------------------ALYGT-------------------------- O93394_PERFV O93394_PERFV TRKAFRK----------------------ALSGT-------------------------- Q4SPQ9_TETNG Q4SPQ9_TETNG TRKEFRK----------------------VVFGM-------------------------- MATCH . * CONSENSUS ????????????????????????????????GT??????????????????????????

Q4RZ05_TETNG Q4RZ05_TETNG -------EQQLDLGRLCLTQANKHFGMALGALFVQQHFSSQSKAK--------------- Q5XHE7_XENLA Q5XHE7_XENLA -------EKQAELTKVCLTQANKHFGMALGALFVEEYFSSSSKAK--------------- ECEL1_HUMAN ECEL1_HUMAN -------DKPQELARVCLGQANRHFGMALGALFVHEHFSAASKAK--------------- ECEL1_RAT ECEL1_RAT -------DKPQELARVCLGQANRHFGMALGALFVHEHFSAASKAK--------------- ECEL1_MOUSE ECEL1_MOUSE -------DKPQELARVCLGQANRHFGMALGALFVHEHFSAASKAK--------------- Q6PFG4_MOUSE Q6PFG4_MOUSE -------DKPQELARVCLGQANRHFGMALGALFVHEHFSAASKAK--------------- Q3TX93_MOUSE Q3TX93_MOUSE -------DKPQELARVCLGQANRHFGMALGALFVHEHFSAASKAK--------------- Q4SB05_TETNG Q4SB05_TETNG -------KSCTPRWQTCIENTDDTLGFALGALFVKATFDKKSKDI--------------- B4DKF3_HUMAN B4DKF3_HUMAN -------KSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSKEI--------------- ECE2_BOVIN ECE2_BOVIN -------KSCTPRWQTCISNTDDALGFALGSLFVKATFDRQSKEI--------------- Q865C2_BOVIN Q865C2_BOVIN -------KSCTPRWQTCISNTDDALGFALGSLFVKATFDRQSKEI--------------- Q865C3_BOVIN Q865C3_BOVIN -------KSCTPRWQTCISNTDDALGFALGSLFVKATFDRQSKEI--------------- B4DF19_HUMAN B4DF19_HUMAN -------KSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSKEI--------------- ECE2_HUMAN ECE2_HUMAN -------KSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSKEI--------------- B4DHU4_HUMAN B4DHU4_HUMAN -------KSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSKEI--------------- Q6UW36_HUMAN Q6UW36_HUMAN -------KSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSKEI--------------- A5PLK8_HUMAN A5PLK8_HUMAN -------KSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSKEI--------------- Q8NFD7_HUMAN Q8NFD7_HUMAN -------KSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSKEI--------------- Q6IE65_RAT Q6IE65_RAT -------KSCTPRWQTCISNTDDALGFALGSLFVKATFDRQSKEI--------------- ECE2_MOUSE ECE2_MOUSE -------KSCTPRWQTCISNTDDALGFALGSLFVKATFDRQSKEI--------------- Q80Z57_MOUSE Q80Z57_MOUSE -------KSCTPRWQTCISNTDDALGFALGSLFVKATFDRQSKEI--------------- Q80Z58_MOUSE Q80Z58_MOUSE -------KSCTPRWQTCISNTDDALGFALGSLFVKATFDRQSKEI--------------- Q8K0P0_MOUSE Q8K0P0_MOUSE -------KSCTPRWQTCISNTDDALGFALGSLFVKATFDRQSKEI--------------- Q8C099_MOUSE Q8C099_MOUSE -------KSCTPRWQTCISNTDDALGFALGSLFVKATFDRQSKEI--------------- B2RQR8_MOUSE B2RQR8_MOUSE -------KSCTPRWQTCISNTDDALGFALGSLFVKATFDRQSKEI--------------- Q923T6_MOUSE Q923T6_MOUSE -------KSCTPRWQTCISNTDDALGFALGSLFVKATFDRQSKEI--------------- Q4T614_TETNG Q4T614_TETNG RKPVFGTKSCTPRWKLCVSDTDSALGFAVGAMFVKDIFAEDSKAVVSVRRSCARCGRTRA A0JMP1_DANRE A0JMP1_DANRE -------KSCMPRWKLCVSDTDSALGFALGALFVKATFSEDSKAF--------------- A7LFV7_FUNHE A7LFV7_FUNHE -------KSCTPRWKLCVSDTDSALGFALGALFVKDTFAEDSKAN--------------- Q32NT6_XENLA Q32NT6_XENLA -------KTCLPRWKFCIRDTDNNLGFALGAMFVKATFAETSKVQ--------------- B6RBR2_XENLA B6RBR2_XENLA -------KTCLPRWKFCIRDTDNNLGFALGAMFVKATFAETSKVQ--------------- Q7ZTK3_XENLA Q7ZTK3_XENLA -------KTCLPRWKFCIRDTDNNLGFALGAMFVKATFAETSKVQ--------------- Q9DGN6_CHICK Q9DGN6_CHICK -------KTCLPRWKFCISDTDNNLGFALGAMFVKATFAEDSKQV--------------- ECE1_CAVPO ECE1_CAVPO -------KTCLPRWKFCVSDTENNLGFGLGPMFVKATFAEDSKNI--------------- Q2Z2K8_HUMAN Q2Z2K8_HUMAN -------KTCLPRWKFCVSDTENNLGFALGPMFVKATFAEDSKSI--------------- B4DKB2_HUMAN B4DKB2_HUMAN -------KTCLPRWKFCVSDTENNLGFALGPMFVKATFAEDSKSI--------------- ECE1_HUMAN ECE1_HUMAN -------KTCLPRWKFCVSDTENNLGFALGPMFVKATFAEDSKSI--------------- ECE1_RAT ECE1_RAT -------KTCLPRWKFCVSDTENNLGFALGPMFVKATFAEDSKNI--------------- ECE1_MOUSE ECE1_MOUSE -------KTCIPRWKFCVSDTENNLGFALGPMFVKATFAEDSKNI--------------- Q6IN10_RAT Q6IN10_RAT -------KTCLPRWKFCVSDTENNLGFALGPMFVKATFAEDSKNI--------------- Q3HTT4_CANFA Q3HTT4_CANFA -------KTXLPRWKFCVSDTENNXGFALXPMFVKATFAEDSKSI--------------- ECE1_BOVIN ECE1_BOVIN -------KTCLPRWKFCVSDTENTLGFALGPMFVKATFAEDSKNI--------------- Q28010_BOVIN Q28010_BOVIN -------KTCLPRWKFCVSDTENTLGFALGPMFVKATFAEDSKNI--------------- Q28868_BOVIN Q28868_BOVIN -------KTCLPRWKFCVSDTENTLGFALGPMFVKATFAEDSKNI--------------- O35812_RAT O35812_RAT -------TTLLPQWDKCVNFIESALPYVVGKMFVNVHFQEDKKEM--------------- A2ICR0_MOUSE A2ICR0_MOUSE -------TTLLPQWDKCVNFIESALPYVVGKMFVNVHFQEDKKEM--------------- Q3TYM9_MOUSE Q3TYM9_MOUSE -------TTLLPQWDKCVNFIESALPYVVGKMFVNVHFQEDKKEM--------------- PHEX_MOUSE PHEX_MOUSE -------TTLLPQWDKCVNFIESALPYVVGKMFVNVHFQEDKKEM--------------- A2AC80_MOUSE A2AC80_MOUSE -------TTLLPQWDKCVNFIESALPYVVGKMFVNVHFQEDKKEM--------------- B4E334_HUMAN B4E334_HUMAN -------TTLLPQWDKCVNFIESALPYVVGKMFVDVYFQEDKKEM--------------- B4DNS0_HUMAN B4DNS0_HUMAN -------TTLLPQWDKCVNFIESALPYVVGKMFVDVYFQEDKKEM--------------- B4DWG8_HUMAN B4DWG8_HUMAN -------TTLLPQWDKCVNFIESALPYVVGKMFVDVYFQEDKKEM--------------- PHEX_HUMAN PHEX_HUMAN -------TTLLPQWDKCVNFIESALPYVVGKMFVDVYFQEDKKEM--------------- A4QP66_DANRE A4QP66_DANRE -------TSLTPRWDKCVNYVENTLIYAAGRLFVDKHFQEDKKHM--------------- Q4S1N5_TETNG Q4S1N5_TETNG -------TSLTPRWDKCVNFVEGSLSYATGRIFVDKHFQEDKKLVSALLRMA-------- B9DI79_HUMAN B9DI79_HUMAN -------MVEEVRWRECVGYVNSNMENAVGSLYVREAFPGDSKSM--------------- MMEL1_HUMAN MMEL1_HUMAN -------MVEEVRWRECVGYVNSNMENAVGSLYVREAFPGDSKSM--------------- B3KS82_HUMAN B3KS82_HUMAN -------MVEEVRWRECVGYVNSNMENAVGSLYVREAFPGDSKSM--------------- MMEL1_RAT MMEL1_RAT -------TMEEVRWRECVSYVNSNMESAVGSLYIKRAFSKDSKSI--------------- B1AS15_MOUSE B1AS15_MOUSE -------TVEEVRWRECVSYVNSNMESAVGSLYIKRAFSKDSKST--------------- B1AS16_MOUSE B1AS16_MOUSE -------TVEEVRWRECVSYVNSNMESAVGSLYIKRAFSKDSKST--------------- B1AS17_MOUSE B1AS17_MOUSE -------TVEEVRWRECVSYVNSNMESAVGSLYIKRAFSKDSKST--------------- B2RPX5_MOUSE B2RPX5_MOUSE -------TVEEVRWRECVSYVNSNMESAVGSLYIKRAFSKDSKST--------------- MMEL1_MOUSE MMEL1_MOUSE -------TVEEVRWRECVSYVNSNMESAVGSLYIKRAFSKDSKST--------------- Q4RX51_TETNG Q4RX51_TETNG -------TAEDAWWRECVRYVQSSMENAVGALYVRETFAGESKQM--------------- B1WAX2_XENTR B1WAX2_XENTR -------TLEEARWRECVSYVNSNMENAVGAMYVKETFAGESKRM--------------- Q67BJ2_CHICK Q67BJ2_CHICK -------TSETAVWRRCANYVNGNMENAVGRLYVQEAFAGDSKHV--------------- NEP_RABIT NEP_RABIT -------TSESATWRRCANYVNGNMENAVGRLYVEAAFAGESKHV--------------- NEP_PONAB NEP_PONAB -------TSETATWRRCANYVNGNMENAVGRLYVEAAFAGESKHV--------------- B7ZKY6_HUMAN B7ZKY6_HUMAN -------TSETATWRRCANYVNGNMKNAVGRLYVEAAFAGESKHV--------------- NEP_HUMAN NEP_HUMAN -------TSETATWRRCANYVNGNMENAVGRLYVEAAFAGESKHV--------------- NEP_MOUSE NEP_MOUSE -------TSETATWRRCANYVNGNMENAVGRLYVEAAFAGESKHV--------------- NEP_RAT NEP_RAT -------TSETATWRRCANYVNGNMENAVGRLYVEAAFAGESKHV--------------- O93394_PERFV O93394_PERFV -------TSEAAVWRQCALYVNNNMDNAVGRLYVQEAFSEKSKEL--------------- Q4SPQ9_TETNG Q4SPQ9_TETNG -------TKEIETWRQCVGFVNSNMDEAVGRLYVERAFSEKSKEL--------------- MATCH * : ::: * .* CONSENSUS ?????????????W??C??????????A?G???V???F???SK?????????????????

Q4RZ05_TETNG Q4RZ05_TETNG -----------VQELVEDIKHSLDVRLQELD-WMDETTKEAARAK--------------L Q5XHE7_XENLA Q5XHE7_XENLA -----------VQQLVENIKHILDNRLEELD-WMDTETKEAAREK--------------L ECEL1_HUMAN ECEL1_HUMAN -----------VQQLVEDIKYILGQRLEELD-WMDAETRAAARAK--------------L ECEL1_RAT ECEL1_RAT -----------VQQLVEDIKYILGQRLEELD-WMDAQTKAAARAK--------------L ECEL1_MOUSE ECEL1_MOUSE -----------VQQLVEDIKYILGQRLEELD-WMDAQTKAAARAK--------------L Q6PFG4_MOUSE Q6PFG4_MOUSE -----------VQQLVEDIKYILGQRLEELD-WMDAQTKAAARAK--------------L Q3TX93_MOUSE Q3TX93_MOUSE -----------VQQLVEDIKYILGQRLEELD-WMDAQTKAAARAK--------------L Q4SB05_TETNG Q4SB05_TETNG -----------AEEMINEIRSAFKEALDRLG-WMDETTRQAAKEK--------------A B4DKF3_HUMAN B4DKF3_HUMAN -----------AEGMISEIRTAFEEALGQLV-WMDEKTRQAAKEK--------------A ECE2_BOVIN ECE2_BOVIN -----------AEGMISEIRVAFEEALGHLV-WMDEKTRQAAKEK--------------A Q865C2_BOVIN Q865C2_BOVIN -----------AEGMISEIRVAFEEALGHLV-WMDEKTRQAAKEK--------------A Q865C3_BOVIN Q865C3_BOVIN -----------AEGMISEIRVAFEEALGHLV-WMDEKTRQAAKEK--------------A B4DF19_HUMAN B4DF19_HUMAN -----------AEGMISEIRTAFEEALGQLV-WMDEKTRQAAKEK--------------A ECE2_HUMAN ECE2_HUMAN -----------AEGMISEIRTAFEEALGQLV-WMDEKTRQAAKEK--------------A B4DHU4_HUMAN B4DHU4_HUMAN -----------AEGMISEIRTAFEEALGQLV-WMDEKTRQAAKEK--------------A Q6UW36_HUMAN Q6UW36_HUMAN -----------AEGMISEIRTAFEEALGQLV-WMDEKTRQAAKEK--------------A A5PLK8_HUMAN A5PLK8_HUMAN -----------AEGMISEIRTAFEEALGQLV-WMDEKTRQAAKEK--------------A Q8NFD7_HUMAN Q8NFD7_HUMAN -----------AEGMISEIRTAFEEALGQLV-WMDEKTRQAAKEK--------------A Q6IE65_RAT Q6IE65_RAT -----------AEGMISEIRAAFEETLENLV-WMDEKTRLAAKEK--------------A ECE2_MOUSE ECE2_MOUSE -----------AEGMINEIRSAFEETLGDLV-WMDEKTRLAAKEK--------------A Q80Z57_MOUSE Q80Z57_MOUSE -----------AEGMINEIRSAFEETLGDLV-WMDEKTRLAAKEK--------------A Q80Z58_MOUSE Q80Z58_MOUSE -----------AEGMINEIRSAFEETLGDLV-WMDEKTRLAAKEK--------------A Q8K0P0_MOUSE Q8K0P0_MOUSE -----------AEGMINEIRSAFEETLGDLV-WMDEKTRLAAKEK--------------A Q8C099_MOUSE Q8C099_MOUSE -----------AEGMINEIRSAFEETLGDLV-WMDEKTRLAAKEK--------------A B2RQR8_MOUSE B2RQR8_MOUSE -----------AEGMINEIRSAFEETLGDLV-WMDEKTRLAAKEK--------------A Q923T6_MOUSE Q923T6_MOUSE -----------AEGMINEIRSAFEETLGDLV-WMDEKTRLAAKEK--------------A Q4T614_TETNG Q4T614_TETNG RSAAVCLCAPQVEDMVTTIKRAFEENLQRVS-WMDSETKKAAKEK--------------A A0JMP1_DANRE A0JMP1_DANRE -----------VEDMVSEIKWAFEDSLKTVS-WMDPETKKAAKEK--------------A A7LFV7_FUNHE A7LFV7_FUNHE -----------VEEMVAEIKWAFEDSLKDVS-WMDLDTKKAAKEK--------------A Q32NT6_XENLA Q32NT6_XENLA -----------ALRMIKEIKAAFEENLKTLS-WMDDETRRAAREK--------------A B6RBR2_XENLA B6RBR2_XENLA -----------ALRMIKEIKAAFEENLKTLS-WMDDETRRAAREK--------------A Q7ZTK3_XENLA Q7ZTK3_XENLA -----------ALRMIKEIKAAFEENLKTLS-WMDDETRRAAREK--------------A Q9DGN6_CHICK Q9DGN6_CHICK -----------AEEMIAEIKTAFEESLETLQ-WMDEETRKSAKEK--------------A ECE1_CAVPO ECE1_CAVPO -----------ASEIILEIKKAFEESLSTLK-WMDEDTRKSAKEK--------------A Q2Z2K8_HUMAN Q2Z2K8_HUMAN -----------ATEIILEIKKAFEESLSTLK-WMDEETRKSAKEK--------------A B4DKB2_HUMAN B4DKB2_HUMAN -----------ATEIILEIKKAFEESLSTLK-WMDEETRKSAKEK--------------A ECE1_HUMAN ECE1_HUMAN -----------ATEIILEIKKAFEESLSTLK-WMDEETRKSAKEK--------------A ECE1_RAT ECE1_RAT -----------ASEIILEIKKAFEESLSTLK-WMDEDTRRSAKEK--------------A ECE1_MOUSE ECE1_MOUSE -----------ASEIIMEIKKAFEESLSTLK-WMDEETRRSAKEK--------------A Q6IN10_RAT Q6IN10_RAT -----------ASEIILEIKKAFEESLSTLK-WMDEDTRRSAKEK--------------A Q3HTT4_CANFA Q3HTT4_CANFA -----------ASEIILEIKKAFEESLSTLK-WMDEETRRSAKEK--------------A ECE1_BOVIN ECE1_BOVIN -----------ASEIILEIKKAFEESLSTLK-WMDEDTRKSAKEK--------------A Q28010_BOVIN Q28010_BOVIN -----------ASEIILEIKKAFEESLSTLK-WMDEDTRKSAKEK--------------A Q28868_BOVIN Q28868_BOVIN -----------ASEIILEIKKAFEESLSTLK-WMDEDTRKSAKEK--------------A O35812_RAT O35812_RAT -----------MEELIEGVRWAFIDMLEKENEWMDAGTKRKAQEK--------------A A2ICR0_MOUSE A2ICR0_MOUSE -----------MEELIEGVRWAFIDMLEKENEWMDAGTKRKAQEK--------------A Q3TYM9_MOUSE Q3TYM9_MOUSE -----------MEELIEGVRWAFIDMLEKENEWMDAGTKRKAQEK--------------A PHEX_MOUSE PHEX_MOUSE -----------MEELIEGVRWAFIDMLEKENEWMDAGTKRKAQEK--------------A A2AC80_MOUSE A2AC80_MOUSE -----------MEELIEGVRWAFIDMLEKENEWMDAGTKRKAQEK--------------A B4E334_HUMAN B4E334_HUMAN -----------MEELVEGVRWAFIDMLEKENEWMDAGTKRKAKEK--------------A B4DNS0_HUMAN B4DNS0_HUMAN -----------MEELVEGVRWAFIDMLEKENEWMDAGTKRKAKEK--------------A B4DWG8_HUMAN B4DWG8_HUMAN -----------MEELVEGVRWAFIDMLEKENEWMDAGTKRKAKEK--------------A PHEX_HUMAN PHEX_HUMAN -----------MEELVEGVRWAFIDMLEKENEWMDAGTKRKAKEK--------------A A4QP66_DANRE A4QP66_DANRE -----------MEELINGIRWAFIDILEKENEWMDEETKRKAIDK--------------A Q4S1N5_TETNG Q4S1N5_TETNG ----------QMEELIEGIRWAFIDILEKENDWMDPPTKKKAIEK--------------A B9DI79_HUMAN B9DI79_HUMAN -----------VRELIDKVRTVFVETLDELG-WMDEESKKKAQEK--------------A MMEL1_HUMAN MMEL1_HUMAN -----------VRELIDKVRTVFVETLDELG-WMDEESKKKAQEK--------------A B3KS82_HUMAN B3KS82_HUMAN -----------VRELIDKVRTVFVETLDELG-WMDEESKKKAQEK--------------A MMEL1_RAT MMEL1_RAT -----------VSELIEKIRSVFVDNLDELN-WMDEESKKKAQEK--------------A B1AS15_MOUSE B1AS15_MOUSE -----------VRELIEKIRSVFVDNLDELN-WMDEESKKKAQEK--------------A B1AS16_MOUSE B1AS16_MOUSE -----------VRELIEKIRSVFVDNLDELN-WMDEESKKKAQEK--------------A B1AS17_MOUSE B1AS17_MOUSE -----------VRELIEKIRSVFVDNLDELN-WMDEESKKKAQEK--------------A B2RPX5_MOUSE B2RPX5_MOUSE -----------VRELIEKIRSVFVDNLDELN-WMDEESKKKAQEK--------------A MMEL1_MOUSE MMEL1_MOUSE -----------VRELIEKIRSVFVDNLDELN-WMDEESKKKAQEK--------------A Q4RX51_TETNG Q4RX51_TETNG -----------VSDLIRKIQKAYVETLEELR-WMDAPSKEKAREKVPETPKKDHSDVPQA B1WAX2_XENTR B1WAX2_XENTR -----------ISDLINKVREAFIETLDELQ-WMDETSKDKAREK--------------A Q67BJ2_CHICK Q67BJ2_CHICK -----------VEEMIADIRGVFIETLDDLT-WMDAETKKKAEQK--------------A NEP_RABIT NEP_RABIT -----------VEDLIAQIREVFIQTLDDLT-WMDAETKKKAEEK--------------A NEP_PONAB NEP_PONAB -----------VEDLIAQIREVFIQTLDDLT-WMDAETKKRAEEK--------------A B7ZKY6_HUMAN B7ZKY6_HUMAN -----------VEDLIAQIREVFIQTLDDLT-WMDAETKKRAEEK--------------A NEP_HUMAN NEP_HUMAN -----------VEDLIAQIREVFIQTLDDLT-WMDAETKKRAEEK--------------A NEP_MOUSE NEP_MOUSE -----------VEDLIAQIREVFIQTLDDLT-WMDAETKKKAEEK--------------A NEP_RAT NEP_RAT -----------VEDLIAQIREVFIQTLDDLT-WMDAETKKKAEEK--------------A O93394_PERFV O93394_PERFV -----------MEEMIKDIREVFISNLDDLT-WMDAETKKAAEEK--------------A Q4SPQ9_TETNG Q4SPQ9_TETNG -----------IIEMIKEIQDVFISNLEQLS-WMDTQTKEAAKEK--------------- MATCH :: :: * *** :: * * CONSENSUS ???????????????I??I???F???L??L??WMD??T???A?EK??????????????A

Q4RZ05_TETNG Q4RZ05_TETNG KYMMVMTGYPDFLLKPE--LIDQEY-GFEVDEKTYFKNILNSIKFNIKLSVKK-IHEEVD Q5XHE7_XENLA Q5XHE7_XENLA KHMMVMIGYPDILLQPE--SMDKEY-EFEVNEKTYFKNILSSIRYSIKMAVKK-IRQEVD ECEL1_HUMAN ECEL1_HUMAN QYMMVMVGYPDFLLKPD--AVDKEY-EFEVHEKTYFKNILNSIRFSIQLSVKK-IRQEVD ECEL1_RAT ECEL1_RAT QYMMVMVGYPDFLLKPE--AVDKEY-EFEVHEKTYLKNILNSIRFSIQLSVKK-IRQEVD ECEL1_MOUSE ECEL1_MOUSE QYMMVMVGYPDFLLKPE--AVDKEY-EFEVHEKTYFKNILNSIRFSIQLSVKK-IRQEVD Q6PFG4_MOUSE Q6PFG4_MOUSE QYMMVMVGYPDFLLKPE--AVDKEY-EFEVHEKTYFKNILNSIRFSIQLSVKK-IRQEVD Q3TX93_MOUSE Q3TX93_MOUSE QYMMVMVGYPDFLLKPE--AVDKEY-EFEVHEKTYFKNILNSIRFSIQLSVKK-IRQEVD Q4SB05_TETNG Q4SB05_TETNG DAIYDMIGFPEFILDPK--ELDDVYDGYEVSDESFFQNMLNFYNFSSRVMADQ-LRKPPN B4DKF3_HUMAN B4DKF3_HUMAN DAIYDMIGFPDFILEPK--ELDDVYDGYEISEDSFFQNMLNLYNFSAKVMADQ-LRKSPS ECE2_BOVIN ECE2_BOVIN DAIYDMIGFPDFILEPK--ELDDVYDGYEVSEDSFFQNMLNLYNFSAKVMADQ-LRKPPS Q865C2_BOVIN Q865C2_BOVIN DAIYDMIGFPDFILEPK--ELDDVYDGYEVSEDSFFQNMLNLYNFSAKVMADQ-LRKPPS Q865C3_BOVIN Q865C3_BOVIN DAIYDMIGFPDFILEPK--ELDDVYDGYEVSEDSFFQNMLNLYNFSAKVMADQ-LRKPPS B4DF19_HUMAN B4DF19_HUMAN DAIYDMIGFPDFILGPK--ELDDVYDGYEISEDSFFQNMLNLYNFSAKVMADQ-LRKPPS ECE2_HUMAN ECE2_HUMAN DAIYDMIGFPDFILEPK--ELDDVYDGYEISEDSFFQNMLNLYNFSAKVMADQ-LRKPPS B4DHU4_HUMAN B4DHU4_HUMAN DAIYDMIGFPDFILEPK--ELDDVYDGYEISEDSFFQNMLNLYNFSAKVMADQ-LRKPPS Q6UW36_HUMAN Q6UW36_HUMAN DAIYDMIGFPDFILEPK--ELDDVYDGYEISEDSFFQNMLNLYNFSAKVMADQ-LRKPPS A5PLK8_HUMAN A5PLK8_HUMAN DAIYDMIGFPDFILEPK--ELDDVYDGYEISEDSFFQNMLNLYNFSAKVMADQ-LRKPPS Q8NFD7_HUMAN Q8NFD7_HUMAN DAIYDMIGFPDFILEPK--ELDDVYDGYEISEDSFFQNMLNLYNFSAKVMADQ-LRKPPS Q6IE65_RAT Q6IE65_RAT DAIYDMIGFPDFILEPR--ELDDVYDGYEVSEDSFFQNMLNLYNFSAKVMADQ-LRKPPS ECE2_MOUSE ECE2_MOUSE DAIYDMIGFPDFILEPK--ELDDVYYGYEVSEDSFFQNMLNLYNFSAKVMADQ-LRKPPS Q80Z57_MOUSE Q80Z57_MOUSE DAIYDMIGFPDFILEPK--ELDDVYYGYEVSEDSFFQNMLNLYNFSAKVMADQ-LRKPPS Q80Z58_MOUSE Q80Z58_MOUSE DAIYDMIGFPDFILEPK--ELDDVYYGYEVSEDSFFQNMLNLYNFSAKVMADQ-LRKPPS Q8K0P0_MOUSE Q8K0P0_MOUSE DAIYDMIGFPDFILEPK--ELDDVYDGYEVSEDSFFQNMLNLYNFSAKVMADQ-LRKPPS Q8C099_MOUSE Q8C099_MOUSE DAIYDMIGFPDFILEPK--ELDDVYDGYEVSEDSFFQNMLNLYNFSAKVMADQ-LRKPPS B2RQR8_MOUSE B2RQR8_MOUSE DAIYDMIGFPDFILEPK--ELDDVYDGYEVSEDSFFQNMLNLYNFSAKVMADQ-LRKPPS Q923T6_MOUSE Q923T6_MOUSE DAIYDMIGFPDFILEPK--ELDDVYDGYEVSEDSFFQNMLNLYNFSAKVMADQ-LRKPPS Q4T614_TETNG Q4T614_TETNG DAIYNMVGYPDFIMNAT--NLDKVFDDFELVSDLYFQNVMKYYNFSGRVNCRPGWRKPHN A0JMP1_DANRE A0JMP1_DANRE DAIYNMVGYPKFIMNPK--ELDKVFNDFDVVSDLYFQNVMNYYNFSARVTADQ-LRKAPN A7LFV7_FUNHE A7LFV7_FUNHE DAIYNMVGYPEFIMNAT--KLDKVFSDFVVVSDLYFQNVMQYYNFSARVTADQ-LRKAPN Q32NT6_XENLA Q32NT6_XENLA EAIYDMIGYPNFIMDPK--ELDKVFNDYDVTDDLYFENGMRFYNFSARVTSDQ-LRKAPS B6RBR2_XENLA B6RBR2_XENLA EAIYDMIGYPNFIMDPK--ELDKVFNDYDVTDDLYFENGMRFYNFSARVTSDQ-LRKAPS Q7ZTK3_XENLA Q7ZTK3_XENLA EAIYDMIGYPNFIMDPK--ELDKVFNDYDVTDDLYFENGMRFYNFSARVTSDQ-LRKAPS Q9DGN6_CHICK Q9DGN6_CHICK DAIYNMIGYPKFILDSK--ELDKVFNDYDAVSDLYFENVMQFYNFSARVTADQ-LRKPPN ECE1_CAVPO ECE1_CAVPO DAIYNMIGYPNFIMDPK--ELDKVFNDYTAVPDLYFENAMRFFNFSWRVTAEQ-LRKAPN Q2Z2K8_HUMAN Q2Z2K8_HUMAN DAIYNMIGYPNFIMDPK--ELDKVFNDYTAVPDLYFENAMRFFNFSWRVTADQ-LRKAPN B4DKB2_HUMAN B4DKB2_HUMAN DAIYNMIGYPNFIMDPK--ELDKVFNDYTAVPDLYFENAMRFFNFSWRVTADQ-LRKAPN ECE1_HUMAN ECE1_HUMAN DAIYNMIGYPNFIMDPK--ELDKVFNDYTAVPDLYFENAMRFFNFSWRVTADQ-LRKAPN ECE1_RAT ECE1_RAT DAIYNMIGYPNFIMDPK--ELDKVFNDYTAVPDLYFENAMRFFNFSLRVTADQ-LRKAPN ECE1_MOUSE ECE1_MOUSE DAIYNMIGYPNFIMDPK--ELDKVFNDYTAVPDLYFENAMRFFNFSWRVTADQ-LRKAPN Q6IN10_RAT Q6IN10_RAT DAIYNMIGYPNFIMDPK--ELDKVFNDYTAVPDLYFENAMRFFNFSWRVTADQ-LRKAPN Q3HTT4_CANFA Q3HTT4_CANFA DAIYNMIGYPNFIMDPK--ELDKVFNDYTAVPDLYFENAMRFFNFSWRVTADQ-LRKAPN ECE1_BOVIN ECE1_BOVIN DAIYNMIGYPNFIMDPK--ELDKVFNDYTAVPDLYFENAMRFFNFSWRVTADQ-LRKAPN Q28010_BOVIN Q28010_BOVIN DAIYNMIGYPNFIMDPK--ELDKVFNDYTAVPDLYFENAMRFFNFSWRVTADQ-LRKAPN Q28868_BOVIN Q28868_BOVIN DAIYNMIGYPNFIMDPK--ELDKVFNDYTAVPDLYFENAMRFFNFSWRVTADQ-LRKAPN O35812_RAT O35812_RAT RAVLAKVGYPEFIMNDT--YVNEDLKAIKFSESDYFGNVLQTRKYLAQSDFFW-LKKAVP A2ICR0_MOUSE A2ICR0_MOUSE RAVLAKVGYPEFIMNDT--YVNEDLKAIKFSESDYFGNVLQTRKYLAQSDFFW-LRKAVP Q3TYM9_MOUSE Q3TYM9_MOUSE RAVLAKVGYPEFIMNDT--YVNEDLKAIKFSESDYFGNVLQTRKYLAQSDFFW-LRKAVP PHEX_MOUSE PHEX_MOUSE RAVLAKVGYPEFIMNDT--YVNEDLKAIKFSESDYFGNVLQTRKYLAQSDFFW-LRKAVP A2AC80_MOUSE A2AC80_MOUSE RAVLAKVGYPEFIMNDT--YVNEDLKAIKFSESDYFGNVLQTRKYLAQSDFFW-LRKAVP B4E334_HUMAN B4E334_HUMAN RAVLAKVGYPEFIMNDT--HVNEDLKAIKFSEADYFGNVLQTRKYLAQSDFFW-LRKAVP B4DNS0_HUMAN B4DNS0_HUMAN RAVLAKVGYPEFIMNDT--HVNEDLKAIKFSEADYFGNVLQTRKYLAQSDFFW-LRKAVP B4DWG8_HUMAN B4DWG8_HUMAN RAVLAKVGYPEFIMNDT--HVNEDLKAIKFSEADYFGNVLQTRKYLAQSDFFW-LRKAVP PHEX_HUMAN PHEX_HUMAN RAVLAKVGYPEFIMNDT--HVNEDLKAIKFSEADYFGNVLQTRKYLAQSDFFW-LRKAVP A4QP66_DANRE A4QP66_DANRE HAVLPKVGYPDFILNDT--YINEDIKRLAFTMTDYFGNVMQTLKFIAQSDIGW-LRKTVP Q4S1N5_TETNG Q4S1N5_TETNG HAVLPKVGYPEFILNNT--YLNEDLKKLQFSEKDYYGNVMQTLKFIGQSDLAW-LRKTVP B9DI79_HUMAN B9DI79_HUMAN MSIREQIGHPDYILEEMNRRLDEEYSNLNFSEDLYFENSLQNLKVGAQRSLRK-LREKVD MMEL1_HUMAN MMEL1_HUMAN MSIREQIGHPDYILEEMNRRLDEEYSNLNFSEDLYFENSLQNLKVGAQRSLRK-LREKVD B3KS82_HUMAN B3KS82_HUMAN MSIREQIGHPDYILEETNRRLDEEYSNLNFSEDLYFENSLQNLKVGAQRSLRK-LREKVD MMEL1_RAT MMEL1_RAT LNIREQIGYPDYILEDNNRHLDEEYSSLTFSEDLYFENGLQNLKNNAQRSLKK-LREKVD B1AS15_MOUSE B1AS15_MOUSE MNIREQIGYPDYILEDNNKHLDEEYSSLTFYEDLYFENGLQNLKNNAQRSLKK-LREKVD B1AS16_MOUSE B1AS16_MOUSE MNIREQIGYPDYILEDNNKHLDEEYSSLTFYEDLYFENGLQNLKNNAQRSLKK-LREKVD B1AS17_MOUSE B1AS17_MOUSE MNIREQIGYPDYILEDNNKHLDEEYSSLTFYEDLYFENGLQNLKNNAQRSLKK-LREKVD B2RPX5_MOUSE B2RPX5_MOUSE MNIREQIGYPDYILEDNNKHLDEEYSSLTFYEDLYFENGLQNLKNNAQRSLKK-LREKVD MMEL1_MOUSE MMEL1_MOUSE MNIREQIGYPDYILEDNNKHLDEEYSSLTFYEDLYFENGLQNLKNNAQRSLKK-LREKVD Q4RX51_TETNG Q4RX51_TETNG MAIKEHIGYPDHILQERNQKLDQEYAHLNFSEEHYFENILENLRCEAHKSLKK-LREPVD B1WAX2_XENTR B1WAX2_XENTR LSIKEQIGYPDYILEDQNDKLDQETAALNFSEYQYFENILEILNSGAQKSLKK-LREPVD Q67BJ2_CHICK Q67BJ2_CHICK TAIKERIGYPDEIMTDDS-KLNSEYQELNYKEEEYFENIIQNLVFTQKKRLKK-LREKVD NEP_RABIT NEP_RABIT LAIKERIGYPDDIVSNDN-KLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKK-LREKVD NEP_PONAB NEP_PONAB LAIKERIGYPDDIVSNDN-KLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKK-LREKVD B7ZKY6_HUMAN B7ZKY6_HUMAN LAIKERIGYPDDIVSNDN-KLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKK-LREKVD NEP_HUMAN NEP_HUMAN LAIKERIGYPDDIVSNDN-KLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKK-LREKVD NEP_MOUSE NEP_MOUSE LAIKERIGYPDDIISNEN-KLNNEYLELNYREDEYFENIIQNLKFSQSKQLKK-LREKVD NEP_RAT NEP_RAT LAIKERIGYPDDIISNEN-KLNNEYLELNYKEEEYFENIIQNLKFSQSKQLKK-LREKVD O93394_PERFV O93394_PERFV RAIRERIGYSDNIKDDK--YLNNEYNDLAYSAEEYFENILQNLEYVQKKRLRK-LRVKVN Q4SPQ9_TETNG Q4SPQ9_TETNG ---------------------------LNFSTDKYFENILHNSEHLQKKRLQK-IHQKVN MATCH : * : : CONSENSUS ???????G?P??I??????????????????????F?N????????????????LR????

Q4RZ05_TETNG Q4RZ05_TETNG KTTWLLPPQALNAYYLPNKNQMVFPAGI-LQPTLY-NPEFPQLEHAAAESKEAELNIISG Q5XHE7_XENLA Q5XHE7_XENLA KSAWLLPPQALNAYYLPNKNQMVFPAGI-LQPTLY-DPDF-------------------- ECEL1_HUMAN ECEL1_HUMAN KSTWLLPPQALNAYYLPNKNQMVFPAGI-LQPTLY-DPDF-------------------- ECEL1_RAT ECEL1_RAT KSTWLLPPQALNAYYLPNKNQMVFPAGI-LQPTLY-DPDF-------------------- ECEL1_MOUSE ECEL1_MOUSE KSTWLLPPQALNAYYLPNKNQMVYPAGI-LQPTLY-DPDF-------------------- Q6PFG4_MOUSE Q6PFG4_MOUSE KSSWLLPPQALNAYYLPNKNQMVFPAGI-LQPTLY-DPDF-------------------- Q3TX93_MOUSE Q3TX93_MOUSE KSSWLLPPQALNAYYLPNKNQMVFPAGI-LQPTLY-DPDF-------------------- Q4SB05_TETNG Q4SB05_TETNG KDQWSMTPPTVNAYYMPTKNGIVFPAGI-LQAPFY-AHDH-------------------- B4DKF3_HUMAN B4DKF3_HUMAN RDQWSMTPQTVNAYYLPTKNEIVFPAGI-LQAPFY-ARNH-------------------- ECE2_BOVIN ECE2_BOVIN RDQWSMTPQTVNAYYLPTKNEIVFPAGI-LQAPFY-TCNH-------------------- Q865C2_BOVIN Q865C2_BOVIN RDQWSMTPQTVNAYYLPTKNEIVFPAGI-LQAPFY-TCNH-------------------- Q865C3_BOVIN Q865C3_BOVIN RDQWSMTPQTVNAYYLPTKNEIVFPAGI-LQAPFY-TCNH-------------------- B4DF19_HUMAN B4DF19_HUMAN RDQWSMTPQTVNAYYLPTKNEIVFPAGI-LQAPFY-ARNH-------------------- ECE2_HUMAN ECE2_HUMAN RDQWSMTPQTVNAYYLPTKNEIVFPAGI-LQAPFY-ARNH-------------------- B4DHU4_HUMAN B4DHU4_HUMAN RDQWSMTPQTVNAYYLPTKNEIVFPAGI-LQAPFY-ARNH-------------------- Q6UW36_HUMAN Q6UW36_HUMAN RDQWSMTPQTVNAYYLPTKNEIVFPAGI-LQAPFY-ARNH-------------------- A5PLK8_HUMAN A5PLK8_HUMAN RDQWSMTPQTVNAYYLPTKNEIVFPAGI-LQAPFY-ARNH-------------------- Q8NFD7_HUMAN Q8NFD7_HUMAN RDQWSMTPQTVNAYYLPTKNEIVFPAGI-LQAPFY-ARNH-------------------- Q6IE65_RAT Q6IE65_RAT RDQWSMTPQTVNAYYLPTKNEIVFPAGI-LQAPFY-AHNH-------------------- ECE2_MOUSE ECE2_MOUSE RDQWSMTPQTVNAYYLPTKNEIVFPAGI-LQPPFY-AHNH-------------------- Q80Z57_MOUSE Q80Z57_MOUSE RDQWSMTPQTVNAYYLPTKNEIVFPAGI-LQPPFY-AHNH-------------------- Q80Z58_MOUSE Q80Z58_MOUSE RDQWSMTPQTVNAYYLPTKNEIVFPAGI-LQPPFY-AHNH-------------------- Q8K0P0_MOUSE Q8K0P0_MOUSE RDQWSMTPQTVNAYYLPTKNEIVFPAGI-LQAPFY-AHNH-------------------- Q8C099_MOUSE Q8C099_MOUSE RDQWSMTPQTVNAYYLPTKNEIVFPAGI-LQAPFY-AHNH-------------------- B2RQR8_MOUSE B2RQR8_MOUSE RDQWSMTPQTVNAYYLPTKNEIVFPAGI-LQAPFY-AHNH-------------------- Q923T6_MOUSE Q923T6_MOUSE RDQWSMTPQTVNAYYLPTKNEIVFPAGI-LQAPFH-AHNH-------------------- Q4T614_TETNG Q4T614_TETNG KKKWSMTPPTVNAYYNPKKNDIVRAEQRNNQAPFY-SRSW-------------------- A0JMP1_DANRE A0JMP1_DANRE RDQWSMTPPTVNAYYNPTKNEMVLPAGI-FQAPFY-NHAW-------------------- A7LFV7_FUNHE A7LFV7_FUNHE RNQWSMTPPTVNAYYNPTKNEMVLPAGI-LQAPFY-SRSW-------------------- Q32NT6_XENLA Q32NT6_XENLA KDQWSMTPPTVNAYYSPTKNEIVFPAGI-LQAPFY-TSTS-------------------- B6RBR2_XENLA B6RBR2_XENLA KDQWSMTPPTVNAYYSPTKNEIVFPAGI-LQAPFY-TSTS-------------------- Q7ZTK3_XENLA Q7ZTK3_XENLA KDQWSMTPPTVNAYYSPTKNEIVFPAGI-LQAPFY-TSTS-------------------- Q9DGN6_CHICK Q9DGN6_CHICK RDQWSMTPPTVNAYYSPTKNEIVFPAGI-LQAPFY-TRAS-------------------- ECE1_CAVPO ECE1_CAVPO RDQWSMTPPMVNAYYSPTKNEIVFPAGI-LPAPFY-TRSS-------------------- Q2Z2K8_HUMAN Q2Z2K8_HUMAN RDQWSMTPPMVNAYYSPTKNEIVFPAGI-LQAPFY-TRSS-------------------- B4DKB2_HUMAN B4DKB2_HUMAN RDQWSMTPPMVNAYYSPTKNEIVFPAGI-LQAPFY-TRSS-------------------- ECE1_HUMAN ECE1_HUMAN RDQWSMTPPMVNAYYSPTKNEIVFPAGI-LQAPFY-TRSS-------------------- ECE1_RAT ECE1_RAT RDQWSMTPPMVNAYYSPTKNEIVFPAGI-LQAPFY-TRSS-------------------- ECE1_MOUSE ECE1_MOUSE RDQWSMTPPMVNAYYSPTKNEIVFPAGI-LQAPFY-TRSS-------------------- Q6IN10_RAT Q6IN10_RAT RDQWSMTPPMVNAYYSPTKNEIVFPAGI-LQAPFY-TRSS-------------------- Q3HTT4_CANFA Q3HTT4_CANFA RDQWSMTPPMVNAYYSPTKNEIVFPAGI-LQAPFY-TRSS-------------------- ECE1_BOVIN ECE1_BOVIN RDQWSMTPPMVNAYYSPTKNEIVFPAGI-LQAPFY-TRSS-------------------- Q28010_BOVIN Q28010_BOVIN RDQWSMTPPMVNAYYSPTKNEIVFPAGI-LQAPFY-TRSS-------------------- Q28868_BOVIN Q28868_BOVIN RDQWSMTPPMVNAYYSPTKNEIVFPAGI-LQAPFY-TRSS-------------------- O35812_RAT O35812_RAT KTEWFTNPTTVNAFYSASTNQIRFPAGE-LQKPFFWGTEY-------------------- A2ICR0_MOUSE A2ICR0_MOUSE KTEWFTNPTTVNAFYSASTNQIRFPAGE-LQKPFFWGTEY-------------------- Q3TYM9_MOUSE Q3TYM9_MOUSE KTEWFTNPTTVNAFYSASTNQIRFPAGE-LQKPFFWGTEY-------------------- PHEX_MOUSE PHEX_MOUSE KTEWFTNPTTVNAFYSASTNQIRFPAGE-LQKPFFWGTEY-------------------- A2AC80_MOUSE A2AC80_MOUSE KTEWFTNPTTVNAFYSASTNQI-------------------------------------- B4E334_HUMAN B4E334_HUMAN KTEWFTNPTTVNAFYSASTNQIRFPAGE-LQKPFFWGTEY-------------------- B4DNS0_HUMAN B4DNS0_HUMAN KTEWFTNPTTVNAFYSASTNQIRFPAGE-LQKPFFWGTEY-------------------- B4DWG8_HUMAN B4DWG8_HUMAN KTEWFTNPTTVNAFYSASTNQIRFPAGE-LQKPFFWGTEY-------------------- PHEX_HUMAN PHEX_HUMAN KTEWFTNPTTVNAFYSASTNQIRFPAGE-LQKPFFWGTEY-------------------- A4QP66_DANRE A4QP66_DANRE RTEWFTNPTTVNAFYSSSTNQIRFPAGE-LQKPFFWGLNY-------------------- Q4S1N5_TETNG Q4S1N5_TETNG RTEWFTNPTTVNAFYSSSTNQIRFPAGE-LQKPFFWGKEY-------------------- B9DI79_HUMAN B9DI79_HUMAN PNLWIIGAAVVNAFYSPNRNQIVFPAGI-LQPPFF-SKEQ-------------------- MMEL1_HUMAN MMEL1_HUMAN PNLWIIGAAVVNAFYSPNRNQIVFPAGI-LQPPFF-SKEQ-------------------- B3KS82_HUMAN B3KS82_HUMAN PNLWIIGAAVVNAFYSPNRNQIVFPAGI-LQPPFF-SKEQ-------------------- MMEL1_RAT MMEL1_RAT QNLWIIGAAVVNAFYSPNRNLIVFPAGI-LQPPFF-SKDQ-------------------- B1AS15_MOUSE B1AS15_MOUSE QNLWIIGAAVVNAFYSPNRNQIVFPAGI-LQPPFF-SKDQ-------------------- B1AS16_MOUSE B1AS16_MOUSE QNLWIIGAAVVNAFYSPNRNQIVFPAGI-LQPPFF-SKDQ-------------------- B1AS17_MOUSE B1AS17_MOUSE QNLWIIGAAVVNAFYSPNRNQIVFPAGI-LQPPFF-SKDQ-------------------- B2RPX5_MOUSE B2RPX5_MOUSE QNLWIIGAAVVNAFYSPNRNQIVFPAGI-LQPPFF-SKDQ-------------------- MMEL1_MOUSE MMEL1_MOUSE QNLWIIGAAVVNAFYSPNRNQIVFPAGI-LQPPFF-SKDQ-------------------- Q4RX51_TETNG Q4RX51_TETNG PDVWIIGAAVVNAFYSPNRNQIVFPAGI-LQPPFF-SKHQ-------------------- B1WAX2_XENTR B1WAX2_XENTR QDAWIIGAAVADAFYSPNRNQIVFPAGI-LQPPFF-NKHQ-------------------- Q67BJ2_CHICK Q67BJ2_CHICK KEEWISGAAVVNAFYSASRNQIVFPAGI-LQPPFF-SASQ-------------------- NEP_RABIT NEP_RABIT KDEWITGAAIVNAFYSSGRNQIVFPAGI-LQPPFF-SAQQ-------------------- NEP_PONAB NEP_PONAB KDEWISGAAVVNAFYSSGRNQIVFPAGI-LQPPFF-SAQQ-------------------- B7ZKY6_HUMAN B7ZKY6_HUMAN KDEWISGAAVVNAFYSSGRNQIVFPAGI-LQPPFF-SAQQ-------------------- NEP_HUMAN NEP_HUMAN KDEWISGAAVVNAFYSSGRNQIVFPAGI-LQPPFF-SAQQ-------------------- NEP_MOUSE NEP_MOUSE KDEWISGAAVVNAFYSSGRNQIVFPAGI-LQPPFF-SAQQ-------------------- NEP_RAT NEP_RAT KDEWISGAAVVNAFYSSGRNQIVFPAGI-LQPPFF-SARQ-------------------- O93394_PERFV O93394_PERFV KEEWVTGAAVVNAFYSSSKNQIVFPAGI-LQPPFF-SKGQ-------------------- Q4SPQ9_TETNG Q4SPQ9_TETNG RETWVTGAAVVNAFYSTSKNQIVFPAGI-LQLPFF-SKSQ-------------------- MATCH * . :*:* . * : CONSENSUS ???W??????VNA?Y????N?IVFPAGI?LQ?PF??????????????????????????

Q4RZ05_TETNG Q4RZ05_TETNG PRSMNYGGIGAIIGHELTHGYDDWVMPWFMSPGGQYDRHGNLKQWWTKESYRKFQTKAEC Q5XHE7_XENLA Q5XHE7_XENLA PQSLNYGGIGTIIGHELTHGYDDW--------GGQYDASGNPIQWWTEDSYSKFLKKAEC ECEL1_HUMAN ECEL1_HUMAN PQSLNYGGIGTIIGHELTHGYDDW--------GGQYDRSGNLLHWWTEASYSRFLRKAEC ECEL1_RAT ECEL1_RAT PQSLNYGGIGTIIGHELTHGYDDW--------GGQYDRSGNLLHWWTEASYSRFLHKAEC ECEL1_MOUSE ECEL1_MOUSE PQSLNYGGIGTIIGHELTHGYDDW--------GGQYDRSGNLLHWWTEASYSRFLHKAEC Q6PFG4_MOUSE Q6PFG4_MOUSE PQSLNYGGIGTIIGHELTHGYDDW--------GGQYDRSGNLLHWWTETSYSHFLRKAEC Q3TX93_MOUSE Q3TX93_MOUSE PQSLNYEGIGTIIGHELTHGYDDW--------GGQYDRSGNLLHWWTETSYSHFLRKAEC Q4SB05_TETNG Q4SB05_TETNG PKALNFGGIGVVMGHELTHAFDDQ--------GREYDKEGNLRPWWQNSSVEAFRERTEC B4DKF3_HUMAN B4DKF3_HUMAN PKALNFGGIGVVMGHELTHAFDDQ--------GREYDKEGNLRPWWQNESLAAFRNHTAC ECE2_BOVIN ECE2_BOVIN PQALNFGGIGVVMGHELTHAFDDQ--------GREYDKEGNLRPWWQNESLAAFRNHTAC Q865C2_BOVIN Q865C2_BOVIN PQALNFGGIGVVMGHELTHAFDDQ--------GREYDKEGNLRPWWQNESLAAFRNHTAC Q865C3_BOVIN Q865C3_BOVIN PQALNFGGIGVVMGHELTHAFDDQ--------GREYDKEGNLRPWWQNESLAAFRNHTAC B4DF19_HUMAN B4DF19_HUMAN PKALNFGGIGVVMGHELTHAFDDQ--------GREYDKEGNLRPWWQNESLAAFRNHTAC ECE2_HUMAN ECE2_HUMAN PKALNFGGIGVVMGHELTHAFDDQ--------GREYDKEGNLRPWWQNESLAAFRNHTAC B4DHU4_HUMAN B4DHU4_HUMAN PKALNFGGIGVVMGHELTHAFDDQ--------GREYDKEGNLRPWWQNESLAAFRNHTAC Q6UW36_HUMAN Q6UW36_HUMAN PKALNFGGIGVVMGHELTHAFDDQ--------GREYDKEGNLRPWWQNESLAAFRNHTAC A5PLK8_HUMAN A5PLK8_HUMAN PKALNFGGIGVVMGHELTHAFDDQ--------GREYDKEGNLRPWWQNESLAAFRNHTAC Q8NFD7_HUMAN Q8NFD7_HUMAN PKALNFGGIGVVMGHELTHAFDDQ--------GREYDKEGNLRPWWQNESLAAFRNHTAC Q6IE65_RAT Q6IE65_RAT PKALNFGGIGVVMGHELTHAFDDQ--------GREYDQEGNLRPWWQNESLTAFQNHTAC ECE2_MOUSE ECE2_MOUSE PKALNFGGIGVVMDHELTHAFDDQ--------GREYDKEGNLRPWWQNESLTAFQNHTAC Q80Z57_MOUSE Q80Z57_MOUSE PKALNFGGIGVVMDHELTHAFDDQ--------GREYDKEGNLRPWWQNESLTAFQNHTAC Q80Z58_MOUSE Q80Z58_MOUSE PKALNFGGIGVVMDHELTHAFDDQ--------GREYDKEGNLRPWWQNESLTAFQNHTAC Q8K0P0_MOUSE Q8K0P0_MOUSE PKALNFGGIGVVMGHELTHAFDDQ--------GREYDKEGNLRPWWQNESLTAFQNHTAC Q8C099_MOUSE Q8C099_MOUSE PKALNFGGIGVVMGHELTHAFDDQ--------GREYDKEGNLRPWWQNESLTAFQNHTAC B2RQR8_MOUSE B2RQR8_MOUSE PKALNFGGIGVVMGHELTHAFDDQ--------GREYDKEGNLRPWWQNESLTAFQNHTAC Q923T6_MOUSE Q923T6_MOUSE PKALNFGGIGVVMGHELTHAFDDQ--------GREYDKEGNLRPWWQNESLTAFQNHTAC Q4T614_TETNG Q4T614_TETNG PAALNFGGIGVVMGHELTHAFDDQ--------GREYDKDGNLRLWWKNSSVEAFKRQTRC A0JMP1_DANRE A0JMP1_DANRE PKAMNFGGIGVVMGHELTHAFDDQ--------GRKYDKDGNLAKWWQNSSVEAFQHQTQC A7LFV7_FUNHE A7LFV7_FUNHE PKALNFGGIGVVMGHELTHAFDDQ--------GREYDKDGNLRSWWKNSSVEAFKRQTQC Q32NT6_XENLA Q32NT6_XENLA PMAQNFGGIGVVIGHELTHAFDDQ--------GREYDKDGNLRPWWKNASVEAFKRQTEC B6RBR2_XENLA B6RBR2_XENLA PMAQNFGGIGVVIGHELTHAFDDQ--------GREYDKDGNLRPWWKNASVEAFKRQTEC Q7ZTK3_XENLA Q7ZTK3_XENLA PMAQNFGGIGVVIGHELTHAFDDQ--------GREYDKDGNLRPWWKNASVEAFKRQTEC Q9DGN6_CHICK Q9DGN6_CHICK PKSLNFGGIGVVVGHELTHAFDDQ--------GREYDKDGNLRPWWKNSSVEAFKRQTAC ECE1_CAVPO ECE1_CAVPO PKALNFGGIGVVVGHELTHAFDDQ--------GREYDKDGNLRPWWKNSSVEAFKQQTEC Q2Z2K8_HUMAN Q2Z2K8_HUMAN PKALNFGGIGVVVGHELTHAFDDQ--------GREYDKDGNLRPWWKNSSVEAFKRQTEC B4DKB2_HUMAN B4DKB2_HUMAN PKALNFGGIGVVVGHELTHAFDDQ--------GREYDKDGNLRPWWKNSSVEAFKRQTEC ECE1_HUMAN ECE1_HUMAN PKALNFGGIGVVVGHELTHAFDDQ--------GREYDKDGNLRPWWKNSSVEAFKRQTEC ECE1_RAT ECE1_RAT PNALNFGGIGVVVGHELTHAFDDQ--------GREYDKDGNLRPWWKNSSVEAFKQQTEC ECE1_MOUSE ECE1_MOUSE PNALNFGGIGVVVGHELTHAFDDQ--------GREYDKDGNLRPWWKNSSVEAFKQQTEC Q6IN10_RAT Q6IN10_RAT PNALNFGGIGVVVGHELTHAFDDQ--------GREYDKDGNLRPWWKNSSVEAFKQQTEC Q3HTT4_CANFA Q3HTT4_CANFA PKALNFGGIGVVVGHELTHAFDDQ--------GREYDKDGNLRPWWKNSSVEAFKQQTEC ECE1_BOVIN ECE1_BOVIN PNALNFGGIGVVVGHELTHAFDDQ--------GREYDKDGNLRPWWKNSSVEAFKQQTAC Q28010_BOVIN Q28010_BOVIN PNALNFGGIGVVVGHELTHAFDDQ--------GREYDKDGNLRPWWKNSSVEAFKQQTAC Q28868_BOVIN Q28868_BOVIN PNALNFGGIGVVVGHELTHAFDDQ--------GREYDKDGNLRPWWKNSSVEAFKQQTAC O35812_RAT O35812_RAT PRSLSYGAIGVIVGHEFTHGFDNN--------GRKYDKNGNLDPWWSVDSEEKFKEKTKC A2ICR0_MOUSE A2ICR0_MOUSE PRSLSYGAIGVIVGHEFTHGFDNN--------GRKYDKNGNLDPWWSVESEEKFKEKTKC Q3TYM9_MOUSE Q3TYM9_MOUSE PRSLSYGAIGVIVGHEFTHGFDNN--------GRKYDKNGNLDPWWSVESEEKFKEKTKC PHEX_MOUSE PHEX_MOUSE PRSLSYGAIGVIVGHEFTHGFDNN--------GRKYDKNGNLDPWWSVESEEKFKEKTKC A2AC80_MOUSE A2AC80_MOUSE ------------------------------------------------------------ B4E334_HUMAN B4E334_HUMAN PRSLSYGAIGVIVGHEFTHGFDNN--------GRKYDKNGNLDPWWSTESEEKFKEKTKC B4DNS0_HUMAN B4DNS0_HUMAN PRSLSYGAIGVIVGHEFTHGFDNN--------GRKYDKNGNLDPWWSTESEEKFKEKTKC B4DWG8_HUMAN B4DWG8_HUMAN PRSLSYGAIGVIVGHEFTHGFDNN--------GRKYDKNGNLDPWWSTESEEKFKEKTKC PHEX_HUMAN PHEX_HUMAN PRSLSYGAIGVIVGHEFTHGFDNN--------GRKYDKNGNLDPWWSTESEEKFKEKTKC A4QP66_DANRE A4QP66_DANRE PRSLSYGAIGVIVGHELTHGFDNN--------GRKYDKDGNLDQ---------------- Q4S1N5_TETNG Q4S1N5_TETNG PRSLSYGAIGVIVGHELTHGFDSN--------GRKYDSNGNLDQWWSNSSITAFSEKTQC B9DI79_HUMAN B9DI79_HUMAN PQALNFGGIGMVIGHEITHGFDDN--------GRNFDKNGNMMDWWSNFSTQHFREQSEC MMEL1_HUMAN MMEL1_HUMAN PQALNFGGIGMVIGHEITHGFDDN--------GRNFDKNGNMMDWWSNFSTQHFREQSEC B3KS82_HUMAN B3KS82_HUMAN PQALNFGGIGMVIGHEITHGFDDN--------GRNFDKNGNMMDWWSNFSTQHFREQSEC MMEL1_RAT MMEL1_RAT PQALNFGGIGMVIGHEITHGFDDN--------GRNFDKNGNMLDWWSNFSARHFRQQSQC B1AS15_MOUSE B1AS15_MOUSE PQSLNFGGIGMVIGHEITHGFDDN--------GRNFDKNGNMLDWWSNFSARHFQQQSQC B1AS16_MOUSE B1AS16_MOUSE PQSLNFGGIGMVIGHEITHGFDDN--------GRNFDKNGNMLDWWSNFSARHFQQQSQC B1AS17_MOUSE B1AS17_MOUSE PQSLNFGGIGMVIGHEITHGFDDN--------GRNFDKNGNMLDWWSNFSARHFQQQSQC B2RPX5_MOUSE B2RPX5_MOUSE PQSLNFGGIGMVIGHEITHGFDDN--------GRNFDKNGNMLDWWSNFSARHFQQQSQC MMEL1_MOUSE MMEL1_MOUSE PQSLNFGGIGMVIGHEITHGFDDN--------GRNFDKNGNMLDWWSNFSARHFQQQSQC Q4RX51_TETNG Q4RX51_TETNG HQALNFGGIGMVIGHEITHGFDDN--------GRNFDKDGNMLNWWSNFSAEHFKEQSQC B1WAX2_XENTR B1WAX2_XENTR PQALNFGGIGMVIGHEITHGFDDN--------GRNFDKDGNMFDWWSNFSAMHFKDQSRC Q67BJ2_CHICK Q67BJ2_CHICK PKSLNYGGIGMVIGHEITHGFDDN--------GRNFNENGDLVDWWTEESARNFKDLSQC NEP_RABIT NEP_RABIT SNSLNYGGIGMVIGHEITHGFDDN--------GRNFNKDGDLVDWWTQQSANNFKEQSQC NEP_PONAB NEP_PONAB SNSLNYGGIGMVIGHEITHGFDDN--------GRNFNKDGDLVDWWTQQSASNFKEQSQC B7ZKY6_HUMAN B7ZKY6_HUMAN SNSLNYGGIGMVIGHEITHGFDDN--------GRNFNKDGDLVDWWTQQSASNFKEQSQC NEP_HUMAN NEP_HUMAN SNSLNYGGIGMVIGHEITHGFDDN--------GRNFNKDGDLVDWWTQQSASNFKEQSQC NEP_MOUSE NEP_MOUSE SNSLNYGGIGMVIGHEITHGFDDN--------GRNFNKDGDLVDWWTQQSANNFKDQSQC NEP_RAT NEP_RAT SNSLNYGGIGMVIGHEITHGFDDN--------GRNFNKDGDLVDWWTQQSANNFKDQSQC O93394_PERFV O93394_PERFV AKSLNYGGIGMVIGHEITHGFDDN--------GRNYDKDGDLKDWWTPGSTDRFLDLSKC Q4SPQ9_TETNG Q4SPQ9_TETNG SNSLNYGGIGMVIGHEITHGFDNN--------GRHYDEKGDLKDWWTPDSNERFLELSKC MATCH CONSENSUS P??LN?GGIG???GHE?TH?FDD?????????GR??DK?GNL??WW???S???F?????C

Q4RZ05_TETNG Q4RZ05_TETNG IVNLYDNFT---VYNQ--KVNGRLTLGENIADMGGLKLSYYAYQKWV---REHGPERPLP Q5XHE7_XENLA Q5XHE7_XENLA IVDLYENFT---VYNQ--RVNGRTTLGENIADLGGLKLAYNAYQKWV---RDNGPERPLP ECEL1_HUMAN ECEL1_HUMAN IVRLYDNFT---VYNQ--RVNGKHTLGENIADMGGLKLAYHAYQKWV---REHGPEHPLP ECEL1_RAT ECEL1_RAT IVRLYDNFT---VYNQ--RVNGKHTLGENIADMGGLKLAYYAYQKWV---REHGPEHPLH ECEL1_MOUSE ECEL1_MOUSE IVRLYDNFT---VYNQ--RVNGKHTLGENIADMGGLKLAYYAYQKWV---REHGPEHPLH Q6PFG4_MOUSE Q6PFG4_MOUSE IVRLYDNFT---VYNQ--RVNGKHTLGENIADMGGLKLAYYAYQKWV---REHGPEHPLH Q3TX93_MOUSE Q3TX93_MOUSE IVRLYDNFT---VYNQ--RVNGKHTLGENIADMGGLKLAYYAYQKWV---REHGPEHPLH Q4SB05_TETNG Q4SB05_TETNG MVDQYSQYL---VNTE--RVNGKQTLGENIADNGGLKAAYHAYQSWV---WKNGEEKRLP B4DKF3_HUMAN B4DKF3_HUMAN MEEQYNQYQ---VNGE--RLNGRQTLGENIADNGGLKAAYNV-SGLT---SPPAAEACWP ECE2_BOVIN ECE2_BOVIN IEEQYSQYQ---VNGE--KLNGRQTLGENIADNGGLKAAYNAYKAWL---RKHGEEQQLP Q865C2_BOVIN Q865C2_BOVIN IEEQYSQYQ---VNGE--KLNGRQTLGENIADNGGLKAAYNAYKAWL---RKHGEEQQLP Q865C3_BOVIN Q865C3_BOVIN IEEQYSQYQ---VNGE--KLNGRQTLGENIADNGGLKAAYNAYKAWL---RKHGEEQQLP B4DF19_HUMAN B4DF19_HUMAN MEEQYNQYQ---VNGE--RLNGRQTLGENIADNGGLKAAYNAYKAWL---RKHGEEQQLP ECE2_HUMAN ECE2_HUMAN MEEQYNQYQ---VNGE--RLNGRQTLGENIADNGGLKAAYNAYKAWL---RKHGEEQQLP B4DHU4_HUMAN B4DHU4_HUMAN MEEQYNQYQ---VNGE--RLNGRQTLGENIADNGGLKAAYNAYKAWL---RKHGEEQQLP Q6UW36_HUMAN Q6UW36_HUMAN MEEQYNQYQ---VNGE--RLNGRQTLGENITDNGGLKAAYNAYKAWL---RKHGEEQQLP A5PLK8_HUMAN A5PLK8_HUMAN MEEQYNQYQ---VNGE--RLNGRQTLGENIADNGGLKAAYNAYKAWL---RKHGEEQQLP Q8NFD7_HUMAN Q8NFD7_HUMAN MEEQYNQYQ---VNGE--RLNGRQTLGENIADNGGLKAAYNAYKAWL---RKHGEEQQLP Q6IE65_RAT Q6IE65_RAT MEEQYNQYQ---VNGE--RLNGLQTLGENIADNGGLKAAYNAYKAWL---RKHGEEQPLP ECE2_MOUSE ECE2_MOUSE MEEQYSQYQ---VNGE--RLNGLQTLGENIADNGGLKAAYNAYKAWL---RKHGEEQPLP Q80Z57_MOUSE Q80Z57_MOUSE MEEQYSQYQ---VNGE--RLNGLQTLGENIADNGGLKAAYNAYKAWL---RKHGEEQPLP Q80Z58_MOUSE Q80Z58_MOUSE MEEQYSQYQ---VNGE--RLNGLQTLGENIADNGGLKAAYNAYKAWL---RKHGEEQPLP Q8K0P0_MOUSE Q8K0P0_MOUSE MEEQYSQYQ---VNGE--RLNGLQTLGENIADNGGLKAAYNAYKAWL---RKHGEEQPLP Q8C099_MOUSE Q8C099_MOUSE MEEQYSQYQ---VNGE--RLNGLQNLGENIADNGGLKAAYNAYKAWL---RKHGEEQPLP B2RQR8_MOUSE B2RQR8_MOUSE MEEQYSQYQ---VNGE--RLNGLQTLGENIADNGGLKAAYNAYKAWL---RKHGEEQPLP Q923T6_MOUSE Q923T6_MOUSE MEEQYSQYQ---VNGE--RLNGLQTLGENIADNGGLKAAYNAYKAWL---RKHGEEQPLP Q4T614_TETNG Q4T614_TETNG MVEQYGNYS---INQE--PVNGIHTLGENIADNGGLKAAYKAYVSWV---ERNGEEALLP A0JMP1_DANRE A0JMP1_DANRE MVEQYSNYS---INNE--PLNGKHTLGENIADNGGLNAAYKAYVNWI---KKNGEEASLP A7LFV7_FUNHE A7LFV7_FUNHE IVEQYGNYS---INKE--LLNGRHTLGENIADNGGLKAAYKAYVNWI---KNNGEEAMLP Q32NT6_XENLA Q32NT6_XENLA ITEQYGNYT---VNGE--AVNGKQTLGENIADNGGLKAAYRAYKNWV---RKNGAEKLLP B6RBR2_XENLA B6RBR2_XENLA ITEQYGNYT---VNGE--AVNGKQTLGENIADNGGLKAAYRAYKNWV---RKNGAEKLLP Q7ZTK3_XENLA Q7ZTK3_XENLA ITEQYGNYT---VNGE--AVNGKQTLGENIADNGGLKAAYRAYKNWV---RKNGAEKLLP Q9DGN6_CHICK Q9DGN6_CHICK MVEQYSNYT---INGE--AVNGKHTLGENIADNGGLKAAYRAYQNWL---RKNGEEETLP ECE1_CAVPO ECE1_CAVPO MVEQYSNYS---VNGE--PVNGRHTLGENIADNGGLKAAYRAYQNWV---KKNGAEETLP Q2Z2K8_HUMAN Q2Z2K8_HUMAN MVEQYSNYS---VNGE--PVNGRHTLGENIADNGGLKAAYRAYQNWV---KKNGAEHSLP B4DKB2_HUMAN B4DKB2_HUMAN MVEQYSNYS---VNGE--PVNGRHTLGENIADNGGLKAAYR------------------- ECE1_HUMAN ECE1_HUMAN MVEQYSNYS---VNGE--PVNGRHTLGENIADNGGLKAAYRAYQNWV---KKNGAEHSLP ECE1_RAT ECE1_RAT MVQQYNNYS---VNGE--PVNGRHTLGENIADNGGLKAAYRAYQNWV---KKNGAEQILP ECE1_MOUSE ECE1_MOUSE MVQQYSNYS---VNGE--PVNGRHTLGENIADNGGLKAAYRAYQNWV---KKNGAEQTLP Q6IN10_RAT Q6IN10_RAT MVQQYNNYS---VNGE--PVNGRHTLGENIADNGGLKAAYRAYQNWV---KKNGAEQILP Q3HTT4_CANFA Q3HTT4_CANFA MVEQYGNYS---VNGE--PVNGRHTLGENIADNGGLKAAYRAYQNWI---KKNGAEQTLP ECE1_BOVIN ECE1_BOVIN MVEQYGNYS---VNGE--PVNGRHTLGENIADNGGLKAAYRAYQNWV---KKNGAEQTLP Q28010_BOVIN Q28010_BOVIN MVEQYGNYS---VNGE--PVNGRHTLGENIADNGGLKAAYRAYQNWV---KKNGAEQTLP Q28868_BOVIN Q28868_BOVIN MVEQYGNYS---VNGE--PVNGRHTLGENIADNGGLKAAYRAYQNWV---KKNGAEQTLP O35812_RAT O35812_RAT MINQYSNYYWKKAGL---NVKGKRTLGENIADNGGLREAFRAYRKWINDRRQGVEEPLLP A2ICR0_MOUSE A2ICR0_MOUSE MINQYSNYYWKKAGL---NVKGKRTLGENIADNGGLREAFRAYRKWINDRRQGVEEPLLP Q3TYM9_MOUSE Q3TYM9_MOUSE MINQYSNYYWKKAGL---NVKGKRTLGENIADNGGLREAFRAYRKWINDRRQGVEEPLLP PHEX_MOUSE PHEX_MOUSE MINQYSNYYWKKAGL---NVKGKRTLGENIADNGGLREAFRAYRKWINDRRQGVEEPLLP A2AC80_MOUSE A2AC80_MOUSE ------------------------------------------------------------ B4E334_HUMAN B4E334_HUMAN MINQYSNYYWKKAGL---NVKGKRTLGENIADNGGLREAFRAYRKWINDRRQGLEEPLLP B4DNS0_HUMAN B4DNS0_HUMAN MVNQYSNYYWKKAGL---NVKGKRTLGENIADNGGLREAFRAYRKWINDRRQGLEEPLLP B4DWG8_HUMAN B4DWG8_HUMAN MINQYSNYYWKKAGL---NVKGKRTLGENIADNGGLREAFRAYRKWINDRRQGLEEPLLP PHEX_HUMAN PHEX_HUMAN MINQYSNYYWKKAGL---NVKGKRTLGENIADNGGLREAFRAYRKWINDRRQGLEEPLLP A4QP66_DANRE A4QP66_DANRE ------------------------------------------------------------ Q4S1N5_TETNG Q4S1N5_TETNG MIDQYNSYYWEKAGLNVRGVRGKRTLAENIADNGGIREAFRAYRRWIDTSRGGAEELLLP B9DI79_HUMAN B9DI79_HUMAN MIYQYGNYSWDLADEQ--NVNGFNTLGENIADNGGVRQAYKAYLKWM---AEGGKDQQLP MMEL1_HUMAN MMEL1_HUMAN MIYQYGNYSWDLADEQ--NVNGFNTLGENIADNGGVRQAYKAYLKWM---AEGGKDQQLP B3KS82_HUMAN B3KS82_HUMAN MIYQYGNYSWDLADGQ--NVNGFNTLGENIADNGGVRQAYKAYLKWM---AEGGKDQQLP MMEL1_RAT MMEL1_RAT MIYQYSNFSWELADNQ--NVNGFSTLGENIADNGGVRQAYKAYLQWL---AEGGRDQRLP B1AS15_MOUSE B1AS15_MOUSE MIYQYGNFSWELADNQ--NVNGFSTLGENIADNGGVRQAYKAYLRWL---ADGGKDQRLP B1AS16_MOUSE B1AS16_MOUSE MIYQYGNFSWELADNQ--NVNGFSTLGENIADNGGVRQAYKAYLRWL---ADGGKDQRLP B1AS17_MOUSE B1AS17_MOUSE MIYQYGNFSWELADNQ--NVNGFSTLGENIADNGGVRQAYKAYLRWL---ADGGKDQRLP B2RPX5_MOUSE B2RPX5_MOUSE MIYQYGNFSWELADNQ--NVNGFSTLGENIADNGGVRQAYKAYLRWL---ADGGKDQRLP MMEL1_MOUSE MMEL1_MOUSE MIYQYGNFSWELADNQ--NVNGFSTLGENIADNGGVRQAYKAYLRWL---ADGGKDQRLP Q4RX51_TETNG Q4RX51_TETNG MVQQYGNFNWKLAGGQ--NVSGISTLGENIADNGGVRQAYKAYLKWV---ETEGEEPRLP B1WAX2_XENTR B1WAX2_XENTR MVYQYGNYTWELAGGQ--NVSGIITLGENIADNGGVRQAYKAYLKWV---ERHGKEPKLP Q67BJ2_CHICK Q67BJ2_CHICK MVYQYGNFSWDLAGGQ--QLSGINTLGENIADNGGVRQAYKAYENFV---KKNGKEKLLP NEP_RABIT NEP_RABIT MVYQYGNFSWDLAGGQ--HLNGINTLGENIADNGGIGQAYRAYQNYV---KKNGEEKLLP NEP_PONAB NEP_PONAB MVYQYGNFSWDLAGGQ--HLNGINTLGENIADNGGLGQAYRAYQNYI---KKNGEEKLLP B7ZKY6_HUMAN B7ZKY6_HUMAN MVYQYGNFSWDLAGGQ--HLNGINTLGENIADNGGLGQAYRAYQNYI---KKNGEEKLLP NEP_HUMAN NEP_HUMAN MVYQYGNFSWDLAGGQ--HLNGINTLGENIADNGGLGQAYRAYQNYI---KKNGEEKLLP NEP_MOUSE NEP_MOUSE MVYQYGNFSWDLAGGQ--HLNGINTLGENIADNGGIGQAYRAYQNYV---KKNGEEKLLP NEP_RAT NEP_RAT MVYQYGNFTWDLAGGQ--HLNGINTLGENIADNGGIGQAYRAYQNYV---KKNGEEKLLP O93394_PERFV O93394_PERFV IVNQYGNFSWDLANGL--HLNGNNTLGENIADNGGIRQAYQAYKNYV---EKHGEEPSLP Q4SPQ9_TETNG Q4SPQ9_TETNG MVNQYNNFTVDAESGT--HMNGKNTLSENIADNGGLRQAFQAYRNHV---TMYGEDPPLP MATCH CONSENSUS ???QY???????????????NG??TLGENIADNGG???AY?AY??W???????G?E??LP

Q4RZ05_TETNG Q4RZ05_TETNG GLRYTHEQLLFVAFAQVKATVWPMVPTPSDCPEAFTLPLTHFCSQNWCMKRRSQSIYLQL Q5XHE7_XENLA Q5XHE7_XENLA RLKYTHDQLFFIAFAQN-----------------------------WCIKRRSQSIYLQV ECEL1_HUMAN ECEL1_HUMAN RLKYTHDQLFFIAFAQN-----------------------------WCIKRRSQSIYLQV ECEL1_RAT ECEL1_RAT RLKYTHNQLFFIAFAQN-----------------------------WCIKRRSQSIYLQV ECEL1_MOUSE ECEL1_MOUSE RLKYTHNQLFFIAFAQN-----------------------------WCIKRRSQSIYLQV Q6PFG4_MOUSE Q6PFG4_MOUSE RLKYTHNQLFFIAFAQN-----------------------------WCIKRRSQSIYLQV Q3TX93_MOUSE Q3TX93_MOUSE RLKYTHNQLFFIAFAQN-----------------------------WCIKRRSQSIYLQV Q4SB05_TETNG Q4SB05_TETNG AVNLTNDQLFFVGFAQV-----------------------------WCSVRTPESAHEGL B4DKF3_HUMAN B4DKF3_HUMAN GVKGAG----------------------------------------WVG-----AGLDGL ECE2_BOVIN ECE2_BOVIN AVGLTNHQLFFVGFAQV-----------------------------WCSVRTPESSHEGL Q865C2_BOVIN Q865C2_BOVIN AVGLTNHQLFFVGFAQV-----------------------------WCSVRTPESSHEGL Q865C3_BOVIN Q865C3_BOVIN AVGLTNHQLFFVGFAQV-----------------------------WCSVRTPESSHEGL B4DF19_HUMAN B4DF19_HUMAN AVGLTNHQLFFVGFAQV------------------------------------------- ECE2_HUMAN ECE2_HUMAN AVGLTNHQLFFVGFAQV-----------------------------WCSVRTPESSHEGL B4DHU4_HUMAN B4DHU4_HUMAN AVGLTNHQLFFVGFAQV-----------------------------WCSVRTPESSREGL Q6UW36_HUMAN Q6UW36_HUMAN AVGLTNHQLFFVGFAQV-----------------------------WCSVRTPESSHEGL A5PLK8_HUMAN A5PLK8_HUMAN AVGLTNHQLFFVGFAQV-----------------------------WCSVRTPESSHEGL Q8NFD7_HUMAN Q8NFD7_HUMAN AVGLTNHQLFFVGFAQV-----------------------------WCSVRTPESSHEGL Q6IE65_RAT Q6IE65_RAT AVGLTNHQLFFVGFAQV-----------------------------WCSVRTPESSHEGL