Alignment of the gene Family HBG005896 of HOVERGEN

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Threshold: 50% 80% 100%
Size: Bigger Smaller Normal
Isoforms are ON
Q1L879_DANRE Q1L879_DANRE RGTAPRVCWMWILLFSV-LIWRVQ---SAGAQSCHEVKTAFQLRQVGSLRWVPETAATDA Q4SHZ8_TETNG Q4SHZ8_TETNG ------------------------------------------------------------ Q4T2U3_TETNG Q4T2U3_TETNG -------------------------------------------------------PLPGA Q6V9Y8_DANRE Q6V9Y8_DANRE MPGLKLYGALILCVLVLPFS-----RPSSQVLDCREVRSSFQ-FLYPGMKWTPETPVSGS A7MB84_BOVIN A7MB84_BOVIN -MSAQTWRVGSQCLLLLALVGSIR---SEGVQSCEEVRKLFQGRLVGPVKGLPDSPRAGP GPC5_HUMAN GPC5_HUMAN -MDAQTWPVGFRCLLLLALVGSAR---SEGVQTCEEVRKLFQWRLLGAVRGLPDSPRAGP GPC5_MOUSE GPC5_MOUSE -MDARTWRLGWRCLLLLALLGSTR---SEGVESCEEVRKLFQWRLGGAVKGLPEAPRAGP A9ULF4_XENTR A9ULF4_XENTR -----MGAFSLALLLAAGLVAVAA---TKGQLSCKEVRASFQ-SLQPGVRWVPESPVSGT GPC3_RAT GPC3_RAT AGTVRTACLLVAMLLGLGCLGQAQ-PPPPPDATCHQVRSFFQ-RLQPGLKWVPETPVPGS Q3TX35_MOUSE Q3TX35_MOUSE AGTVRTACLLVAMLLGLGCLGQAQ-PPPPPDATCHQVRSFFQ-RLQPGLKWVPETPVPGS Q3TWB2_MOUSE Q3TWB2_MOUSE AGTVRTACLLVAMLLGLGCLGQAQ-PPPPPDATCHQVRSFFQ-RLQPGLKWVPETPVPGS GPC3_MOUSE GPC3_MOUSE AGTVRTACLLVAMLLGLGCLGQAQ-PPPPPDATCHQVRSFFQ-RLQPGLKWVPETPVPGS Q9QZF1_MOUSE Q9QZF1_MOUSE AGTVRTACLLVAMLLGLGCLGQAQ-PPPPPDATCHQVRSFFQ-RLQPGLKWVPETPVPGS B1ATR5_MOUSE B1ATR5_MOUSE AGTVRTACLLVAMLLGLGCLGQAQ-PPPPPDATCHQVRSFFQ-RLQPGLKWVPETPVPGS Q3ZBZ6_BOVIN Q3ZBZ6_BOVIN AGTVRTACLVVAMLLSLDCPGQAQPPPPPPDATCHQVRSFFQ-RLQPGLKWVPETPVPGS Q2Q1N3_CEREL Q2Q1N3_CEREL ------------------------------------------------------------ GPC3_PANTR GPC3_PANTR AGTVRTACLVVAMLLSLDFPGQAQPPPPPPDATCHQVRSFFQ-RLQPGLKWVPETPVPGS B4DTD8_HUMAN B4DTD8_HUMAN AGTVRTACLVVAMLLSLDFPGQAQPPPPPPDATCHQVRSFFQ-RLQPGLKWVPETPVPGS Q2L882_HUMAN Q2L882_HUMAN AGTVRTACLVVAMLLSLDFPGQAQPPPPPPDATCHQVRSFFQ-RLQPGLKWVPETPVP-- Q2L880_HUMAN Q2L880_HUMAN AGTVRTACLVVAMLLSLDFPGQAQPPPPPPDATCHQVRSFFQ-RLQPGLKWVPETPVPGS Q53H15_HUMAN Q53H15_HUMAN AGTVRTACLVVAMLLSLDFPGQAQPPPPPPDATCHQVRSFFQ-RLQPGLKWVPETPVPGS Q8IYG2_HUMAN Q8IYG2_HUMAN AGTVRTACLVVAMLLSLDFPGQAQPPPPPPDATCHQVRSFFQ-RLQPGLKWVPETPVPGS GPC3_HUMAN GPC3_HUMAN AGTVRTACLVVAMLLSLDFPGQAQPPPPPPDATCHQVRSFFQ-RLQPGLKWVPETPVPGS MATCH CONSENSUS ?????????????LL??????????????????C??VR??FQ??L???????P??P??G?

Q1L879_DANRE Q1L879_DANRE ELLICKHQGPTCCTRKMEESYYSAAQRDTLQNILSYSFELKYLILGHASSFQ-------- Q4SHZ8_TETNG Q4SHZ8_TETNG ------------------------------------------------------------ Q4T2U3_TETNG Q4T2U3_TETNG DLQVCQTKGPTCCFKKMEERYQVAARSNMELGLQVVSAQLKQLIIQNAAIFQVVAPYHHY Q6V9Y8_DANRE Q6V9Y8_DANRE DLQVCQPKGLTCCSRKMEERYLLIAKQNMESSLQATSAQLKGLIIQNAALFQ-------- A7MB84_BOVIN A7MB84_BOVIN DLQVCTAKKPSCCTRKMEERYQVVARQDMQQVLQTSSSTLKFLISRNAAAFQ-------- GPC5_HUMAN GPC5_HUMAN DLQVCISKKPTCCTRKMEERYQIAARQDMQQFLQTSSSTLKFLISRNAAAFQ-------- GPC5_MOUSE GPC5_MOUSE DLQVCLSKNPTCCTRKMEERYQIAARQDLQQVLQTSSSTLKLLISRNAAAFQ-------- A9ULF4_XENTR A9ULF4_XENTR DLQVCITKTPTCCNRRMEERYQSVSRLNMEQLLQTASAKLKFLIIQNAAIFQ-------- GPC3_RAT GPC3_RAT DLQVCLPKGPTCCSRKMEEKYQLTARLNMEQLLQSASMELKFLIIQNAAVFQ-------- Q3TX35_MOUSE Q3TX35_MOUSE DLQVCLPKGPTCCSRKMEEKYQLTARLNMEQLLQSASMELKFLIIQNAAVFQ-------- Q3TWB2_MOUSE Q3TWB2_MOUSE DLQVCLPKGPTCCSRKMEEKYQLTARLNMEQLLQSASMELKFLIIQNAAVFQ-------- GPC3_MOUSE GPC3_MOUSE DLQVCLPKGPTCCSRKMEEKYQLTARLNMEQLLQSASMELKFLIIQNAAVFQ-------- Q9QZF1_MOUSE Q9QZF1_MOUSE DLQVCLPKGPTCCSRKMEEKYQLTARLNMEQLLQSASMELKFLIIQNAAVFQ-------- B1ATR5_MOUSE B1ATR5_MOUSE DLQVCLPKGPTCCSRKMEEKYQLTARLNMEQLLQSASMELKFLIIQNAAVFQ-------- Q3ZBZ6_BOVIN Q3ZBZ6_BOVIN DLQVCLPKGPTCCSRKMEEKYQLTARLNMEQLLQSASMELKFLIIQNAAVFQ-------- Q2Q1N3_CEREL Q2Q1N3_CEREL --------GPTCCSRKMEEKYQLTARLNMEQLLQSASMELKFLIIQNAAVFQ-------- GPC3_PANTR GPC3_PANTR DLQVCLPKGPTCCSRKMEEKYQLTARLNMEQLLQSASKELKFLIIQNAAVFQ-------- B4DTD8_HUMAN B4DTD8_HUMAN DLQVCLPKGPTCCSRKMEEKYQLTARLNMEQLLQSA------------------------ Q2L882_HUMAN Q2L882_HUMAN ------------------------------------------------------------ Q2L880_HUMAN Q2L880_HUMAN DLQVCLPKGPTCCSRKMEEKYQLTARLNMEQLLQSASMELKFLIIQNAAVFQ-------- Q53H15_HUMAN Q53H15_HUMAN DLQVCLPKGPTCCSRKMEEKYQLTARLNMEQLLQSASMELKFLIIQNAAVFQ-------- Q8IYG2_HUMAN Q8IYG2_HUMAN DLQVCLPKGPTCCSRKMEEKYQLTARLNMEQLLQSASMELKFLIIQNAAVFQ-------- GPC3_HUMAN GPC3_HUMAN DLQVCLPKGPTCCSRKMEEKYQLTARLNMEQLLQSASMELKFLIIQNAAVFQ-------- MATCH CONSENSUS DLQVC??K?PTCC?RKMEE?YQ??AR??M?Q?LQ??S??LK?LI??NAA?FQ????????

Q1L879_DANRE Q1L879_DANRE ------DTFHSLLSFTLNHTNSLFDTTYETISQDARPLVSTLFNDLDLYLRGDDNVSVEH Q4SHZ8_TETNG Q4SHZ8_TETNG ------DTFEVLLKQAENHTNVFLRRSYRSVADEAAGPVGELFTAVGLFLMGSE-LSVEE Q4T2U3_TETNG Q4T2U3_TETNG KYWWYTEAFDLVLRHGRNATLAILKSEFPGLGTGAKNSVGQLFMDMSLYILGSD-SSVDH Q6V9Y8_DANRE Q6V9Y8_DANRE ------EAFDMVLRLGRNSTLMVLREEFPGLGAGASGAVTQLFLDMSLYILGSD-ANVND A7MB84_BOVIN A7MB84_BOVIN ------ETLETLIRQAENYTSILFCNTYRNMALEAAASTQELFTDVGLYLFGAD-VNPEE GPC5_HUMAN GPC5_HUMAN ------ETLETLIKQAENYTSILFCSTYRNMALEAAASVQEFFTDVGLYLFGAD-VNPEE GPC5_MOUSE GPC5_MOUSE ------ETLETLIRQAENYTSILFCNTYRNMALEAAASIQEFFTDVGLYLFGAD-VNPEE A9ULF4_XENTR A9ULF4_XENTR ------EAFEMVIRHARNYTNTMFKTHYQNISSKAMKFVGELFTDISLYLLGSD-INVND GPC3_RAT GPC3_RAT ------EAFEIVVRHAKNYTNAMFKNNYPSLTPQAFEFVGEFFTDVSLYILGSD-INVDD Q3TX35_MOUSE Q3TX35_MOUSE ------EAFEIVVRHAKNYTNAMFKNNYPSLTPQAFEFVGEFFTDVSLYILGSD-INVDD Q3TWB2_MOUSE Q3TWB2_MOUSE ------EAFEIVVRHAKNYTNAMFKNNYPSLTPQAFEFVGEFFTDVSLYILGSD-INVDD GPC3_MOUSE GPC3_MOUSE ------EAFEIVVRHAKNYTNAMFKNNYPSLTPQAFEFVGEFFTDVSLYILGSD-INVDD Q9QZF1_MOUSE Q9QZF1_MOUSE ------EAFEIVVRHAKNYTNAMFKNNYPSLTPQAFEFVGEFFTDVSLYILGSD-INVDD B1ATR5_MOUSE B1ATR5_MOUSE ------EAFEIVVRHAKNYTNAMFKNNYPSLTPQAFEFVGEFFTDVSLYILGSD-INVDD Q3ZBZ6_BOVIN Q3ZBZ6_BOVIN ------EAFEIVVRHAKNYTNAMFKNNYPSLTPQAFDFVGEFFTDVSLYILGSD-INVDD Q2Q1N3_CEREL Q2Q1N3_CEREL ------EAFEIVVRHAKNYTNAMFKNNYPSLTPQAFDFVGEFFTDVSLYILGSD-INVDD GPC3_PANTR GPC3_PANTR ------EAFEIVVRHAKNYTNAMFKNNYPSLTPQAFEFVGEFFTDVSLYILGSD-INVDD B4DTD8_HUMAN B4DTD8_HUMAN ------KAFEIVVRHAKNYTNAMFKNNYPSLTPQAFEFVGEFFTDVSLYILGSD-INVDD Q2L882_HUMAN Q2L882_HUMAN ------EAFEIVVRHAKNYTNAMFKNNYPSLTPQAFEFVGEFFTDVSLYILGSD-INVDD Q2L880_HUMAN Q2L880_HUMAN ------EAFEIVVRHAKNYTNAMFKNNYPSLTPQAFEFVGEFFTDVSLYILGSD-INVDD Q53H15_HUMAN Q53H15_HUMAN ------EAFEIVVRHAKNYTNAMFKNNYPSLTPQAFEFVGEFFTDVSLYILGSD-INVDD Q8IYG2_HUMAN Q8IYG2_HUMAN ------EAFEIVVRHAKNYTNAMFKNNYPSLTPQAFEFVGEFFTDVSLYILGSD-INVDD GPC3_HUMAN GPC3_HUMAN ------EAFEIVVRHAKNYTNAMFKNNYPSLTPQAFEFVGEFFTDVSLYILGSD-INVDD MATCH .::. :: * * .: : : * :* :.*:: * : . :. CONSENSUS ??????E?FE???R?A?NYT???F???Y??????A???V?E?FTDV?LY??GSD??NV??

Q1L879_DANRE Q1L879_DANRE SVYRFYDKLFPLVYQHLVNPGLGSPVSTWSAEGTECLRATRHDIYPFGHHPQELAQGLSK Q4SHZ8_TETNG Q4SHZ8_TETNG SVQRFFDALFPPVYGRLVRPALGDLS----PSFAECVRSSRRDLRPFGATPGILAEQIVQ Q4T2U3_TETNG Q4T2U3_TETNG MVSMLYDRLFLLMNRWLLGASMSSVS-------EECVRRAWKDSGAFGPYPKLVTARLSR Q6V9Y8_DANRE Q6V9Y8_DANRE MVSTFFSRLFPLTYRRLLGNGAVAGI----SE--ECLRGAWKGSSAYGSFPKMMMTRLSR A7MB84_BOVIN A7MB84_BOVIN FVNRFFDSLFPLVYNHLINPGVTDSS----LEYSECIRTARRDISPFGNIPKRVLGQMGR GPC5_HUMAN GPC5_HUMAN FVNRFFDSLFPLVYNHLINPGVTDSS----LEYSECIRMARRDVSPFGNIPQRVMGQMGR GPC5_MOUSE GPC5_MOUSE FVNRFFDSLFPLVYNHLINPGVTDSS----LQYSECIRMARQDVSPFGNIPKRVMGQMGR A9ULF4_XENTR A9ULF4_XENTR MVNEFFDSLFPVLYSHYLNPGV-HVT----VENAECLRLARVDTNAFGQYPKTVMTQVSK GPC3_RAT GPC3_RAT MVNELFDSLFPVIYTQMMNPGLPESV----LDINECLRGARRDLKVFGSFPKLIMTQVSK Q3TX35_MOUSE Q3TX35_MOUSE MVNELFDSLFPVIYTQMMNPGLPESV----LDINECLQGARRDLKVFGSFPKLIMTQVSK Q3TWB2_MOUSE Q3TWB2_MOUSE MVNELFDSLFPVIYTQMMNPGLPESV----LDINECLRGARRDLKVFGSFPKLIMTQVSK GPC3_MOUSE GPC3_MOUSE MVNELFDSLFPVIYTQMMNPGLPESV----LDINECLRGARRDLKVFGSFPKLIMTQVSK Q9QZF1_MOUSE Q9QZF1_MOUSE MVNELFDSLFPVIYTQMMNPGLPESV----LDINECLRGARRDLKVFGSFPKLIMTQVSK B1ATR5_MOUSE B1ATR5_MOUSE MVNELFDSLFPVIYTQMMNPGLPESV----LDINECLRGARRDLKVFGSFPKLIMTQVSK Q3ZBZ6_BOVIN Q3ZBZ6_BOVIN MVNELFDSLFPVIYTQLMNPGLPEST----LDINECLRGARRDLKVFGNFPKLIMTQVSK Q2Q1N3_CEREL Q2Q1N3_CEREL MVNELFDSLFPVIYTQLMNPGLPEST----LDINECLRGARRDLKVFGNFPKLIMTQVSK GPC3_PANTR GPC3_PANTR MVNELFDSLFPVIYTQLMNPGLPDSA----LDINECLRGARRDLKVFGNFPKLIMTQVSK B4DTD8_HUMAN B4DTD8_HUMAN MVNELFDSLFPVIYTQLMNPGLPDSA----LDINECLRGARRDLKVFGNFPKLIMTQVSK Q2L882_HUMAN Q2L882_HUMAN MVNELFDSLFPVIYTQLMNPGLPDSA----LDINECLRGARRDLKVFGNFPKLIMTQVSK Q2L880_HUMAN Q2L880_HUMAN MVNELFDSLFPVIYTQLMNPGLPDSA----LDINECLRGARRDLKVFGNFPKLIMTQVSK Q53H15_HUMAN Q53H15_HUMAN MVNELFDSLFPVIYTQLMNPGLPDSA----LDINECLRGARRDLKVFGNFPKLIMTQVSK Q8IYG2_HUMAN Q8IYG2_HUMAN MVNELFDSLFPVIYTQLMNPGLPDSA----LDINECLRGARRDLKVFGNFPKLIMTQVSK GPC3_HUMAN GPC3_HUMAN MVNELFDSLFPVIYTQLMNPGLPDSA----LDINECLRGARRDLKVFGNFPKLIMTQVSK MATCH * ::. ** : . **:: : . :* * : : : CONSENSUS ?VN??FDSLFP??Y????NPG?????????????EC?R?AR?D???FG??PK??M?Q?S?

Q1L879_DANRE Q1L879_DANRE ALVVGRALSRALAVGADVLNITESVGMGRVCGRALVRMLFCPHC---------------- Q4SHZ8_TETNG Q4SHZ8_TETNG SGVAGKLFLQALHLGLEVINTTDHLQMSRECRRAILKMQYCPFCQVQTNTSGLISSTPIR Q4T2U3_TETNG Q4T2U3_TETNG SLLATRVFLQALNLGIEVVNTTNHLRPNRDCSRALVKLWYCPHC---------------- Q6V9Y8_DANRE Q6V9Y8_DANRE SLLATRVFLQALNLGIEVVNTTQHLRAGRDCGRSLLKLWYCPHC---------------- A7MB84_BOVIN A7MB84_BOVIN SLLPSRTFLQALNLGIEVINTTDHLHFSKECGRALLRMQYCPHC---------------- GPC5_HUMAN GPC5_HUMAN SLLPSRTFLQALNLGIEVINTTDYLHFSKECSRALLKMQYCPHC---------------- GPC5_MOUSE GPC5_MOUSE SLLPGRTFLQALNLGIEVINTTDHIHFSKECSRALLKMQYCPHC---------------- A9ULF4_XENTR A9ULF4_XENTR SLQASRAFLQALNLGIEVINTTDYLKINKDCGRTLMKMWYCSHC---------------- GPC3_RAT GPC3_RAT SLQVTRIFLQALNLGIEVINTTDHLKFSKDCGRMLTRMWYCSYC---------------- Q3TX35_MOUSE Q3TX35_MOUSE SLQVTRIFLQALNLGIEVINTTDHLKFSKDCGRMLTRMWYCSYC---------------- Q3TWB2_MOUSE Q3TWB2_MOUSE SLQVTRIFLQALNLGIEVINTTDHLKFSKDCGRMLTRMWYCSYC---------------- GPC3_MOUSE GPC3_MOUSE SLQVTRIFLQALNLGIEVINTTDHLKFSKDCGRMLTRMWYCSYC---------------- Q9QZF1_MOUSE Q9QZF1_MOUSE SLQVTRIFLQALNLGIEVINTTDHLKFSKDCGRMLTRMWYCSYC---------------- B1ATR5_MOUSE B1ATR5_MOUSE SLQVTRIFLQALNLGIEVINTTDHLKFSKDCGRMLTRMWYCSYC---------------- Q3ZBZ6_BOVIN Q3ZBZ6_BOVIN SLQVTRIFLQALNLGIEVINTTDHLKFSKDCGRMLTRMWYCSYC---------------- Q2Q1N3_CEREL Q2Q1N3_CEREL SLQVTRIFLQALNLGIEVINTTDHLKFSKDCGRMLTRMWYCSYC---------------- GPC3_PANTR GPC3_PANTR SLQVTRIFLQALNLGIEVINTTDHLKFSKDCGRMLTRMWYCSYC---------------- B4DTD8_HUMAN B4DTD8_HUMAN SLQVTRIFLQALNLGIEVINTTDHLKFSKDCGRMLTRMWYCSYC---------------- Q2L882_HUMAN Q2L882_HUMAN SLQVTRIFLQALNLGIEVINTTDHLKFSKDCGRMLTRMWYCSYC---------------- Q2L880_HUMAN Q2L880_HUMAN SLQVTRIFLQALNLGIEVINTTDHLKFSKDCGRMLTRMWYCSYC---------------- Q53H15_HUMAN Q53H15_HUMAN SLQVTRIFLQALNLGIEVINTTDHLKFSKDCGRMLTRMWYCSYC---------------- Q8IYG2_HUMAN Q8IYG2_HUMAN SLQVTRIFLQALNLGIEVINTTDHLKFSKDCGRMLTRMWYCSYC---------------- GPC3_HUMAN GPC3_HUMAN SLQVTRIFLQALNLGIEVINTTDHLKFSKDCGRMLTRMWYCSYC---------------- MATCH : : : :** :* :*:* *: : .: * * : :: :*..* CONSENSUS SL???R?FLQALNLGIEVINTTDHL??SK?CGR?L??M?YC??C????????????????

Q1L879_DANRE Q1L879_DANRE ----------------RGLTLIRPCGGLCLNVMRGCLAGVAELDAPWRDYVSLLEKLSGA Q4SHZ8_TETNG Q4SHZ8_TETNG STSTSEGKALLFPFFPQGLTQSKPCMGYCLNVMRGCLASMAEIDTHWREFVHSLEGLSAR Q4T2U3_TETNG Q4T2U3_TETNG ----------------QGILGQPVCKGFCHMVMHGCLGGVVEVQLHWKNYIERLSKLAGA Q6V9Y8_DANRE Q6V9Y8_DANRE ----------------QSLLEARPCRPLCVSTMGACLGGTTEVQPHWRAYVDELGSLAAA A7MB84_BOVIN A7MB84_BOVIN ----------------QGLALTKPCMGYCLNVMRGCLAHVAELNPHWHVYIRSLEELSDA GPC5_HUMAN GPC5_HUMAN ----------------QGLALTKPCMGYCLNVMRGCLAHMAELNPHWHAYIRSLEELSDA GPC5_MOUSE GPC5_MOUSE ----------------QSLMLSKPCMGYCLNVIRGCLAHMTELNPHWHAYIRSLEELSDA A9ULF4_XENTR A9ULF4_XENTR ----------------QGVLEAKPCAGYCGSTMRTCLVGVVEIDTHWDEYILSIERHTRE GPC3_RAT GPC3_RAT ----------------QGLMMVKPCGGYCNVVMQGCMAGVVEIDKYWREYILSLEELVNG Q3TX35_MOUSE Q3TX35_MOUSE ----------------QGLMMVKPCGGYCNVVMQGCMAGVVEIDKYWREYILSLEELVNG Q3TWB2_MOUSE Q3TWB2_MOUSE ----------------QGLMMVKPCGGYCNVVMQGCMAGVVEIDKYWREYILSLEELVNG GPC3_MOUSE GPC3_MOUSE ----------------QGLMMVKPCGGYCNVVMQGCMAGVVEIDKYWREYILSLEELVNG Q9QZF1_MOUSE Q9QZF1_MOUSE ----------------QGLMMVKPCGGYCNVVMQGCMAGVVEIDKYWREYILSLEELVNG B1ATR5_MOUSE B1ATR5_MOUSE ----------------QGLMMVKPCGGYCNVVMQGCMAGVVEIDKYWREYILSLEELVNG Q3ZBZ6_BOVIN Q3ZBZ6_BOVIN ----------------QGLMMVKPCGGYCNVVMQGCMAGVVEIDKYWREYILSLEELVNG Q2Q1N3_CEREL Q2Q1N3_CEREL ----------------QGLMMVKPCGGYCNVVMQGCMA---------------------- GPC3_PANTR GPC3_PANTR ----------------QGLMMVKPCGGYCNVVMQGCMAGVVEIDKYWREYILSLEELVNG B4DTD8_HUMAN B4DTD8_HUMAN ----------------QGLMMVKPCGGYCNVVMQGCMAGVVEIDKYWREYILSLEELVNG Q2L882_HUMAN Q2L882_HUMAN ----------------QGLMMVKPCGGYCNVVMQGCMAGVVEIDKYWREYILSLEELVNG Q2L880_HUMAN Q2L880_HUMAN ----------------QGLMMVKPCGGYCNVVMQGCMAGVVEIDKYWREYILSLEELVNG Q53H15_HUMAN Q53H15_HUMAN ----------------QGLMMVKPCGGYCNVVMQGCMAGVVEIDKYWREYILSLEELVNG Q8IYG2_HUMAN Q8IYG2_HUMAN ----------------QGLMMVKPCGGYCNVVMQGCMAGVVEIDKYWREYILSLEELVNG GPC3_HUMAN GPC3_HUMAN ----------------QGLMMVKPCGGYCNVVMQGCMAGVVEIDKYWREYILSLEELVNG MATCH :.: * * .: *: CONSENSUS ????????????????QGL???KPC?GYC??VM?GC?A???E????W??YI?SLE?L???

Q1L879_DANRE Q1L879_DANRE LSERYEVELGLLRIRERINDAILTAQLHGPHLSAVVS--------------------HVG Q4SHZ8_TETNG Q4SHZ8_TETNG MHGPQDLEQVLLGAHTLLRDAIGHAQRNAARLSAQ-----------------------VQ Q4T2U3_TETNG Q4T2U3_TETNG MRGEQDMEAVVLILPSMI------------------------------------------ Q6V9Y8_DANRE Q6V9Y8_DANRE MKGEQDIEAVVLRLHVIIRQALKQAVASKSKVSAQ-----------------------VS A7MB84_BOVIN A7MB84_BOVIN MHGTYDIEHVLLNFHLLVNDAVMQAHRDGQKLSEQ-----------------------VN GPC5_HUMAN GPC5_HUMAN MHGTYDIGHVLLNFHLLVNDAVLQAHLNGQKLLEQ-----------------------VN GPC5_MOUSE GPC5_MOUSE MHGTYDVEHVLLNFHLLVNDAVLQAHLNGQKLLDQ-----------------------VN A9ULF4_XENTR A9ULF4_XENTR MYGIYDLENVLLNLFSLIRDAVLHVEKNWAKLSTS-----------------------IN GPC3_RAT GPC3_RAT MYRIYDMENVLLGLFSTIHDSIQYVQKNGGKLTTT-----------------------IG Q3TX35_MOUSE Q3TX35_MOUSE MYRIYDMENVLLGLFSTIHDSIQYVQKNGGKLTTT-----------------------IG Q3TWB2_MOUSE Q3TWB2_MOUSE MYRIYDMENVLLGLFSTIHDSIQYVQKNGGKLTTT-----------------------IG GPC3_MOUSE GPC3_MOUSE MYRIYDMENVLLGLFSTIHDSIQYVQKNGGKLTTT-----------------------IG Q9QZF1_MOUSE Q9QZF1_MOUSE MYRIYDMENVLLGLFSTIHDSIQYVQKNGGKLTTT-----------------------IG B1ATR5_MOUSE B1ATR5_MOUSE MYRIYDMENVLLGLFSTIHDSIQYVQKNGGKLTTT-----------------------IG Q3ZBZ6_BOVIN Q3ZBZ6_BOVIN MYRVYDMENVLLGLFSTIHDSIQYVQKNGGKLTTT-----------------------IG Q2Q1N3_CEREL Q2Q1N3_CEREL ------------------------------------------------------------ GPC3_PANTR GPC3_PANTR MYRIYDMENVLLGLFSTIHDSIQYVQKNAGKLTTT-----------------------IG B4DTD8_HUMAN B4DTD8_HUMAN MYRIYDMENVLLGLFSTIHDSIQYVQKNAGKLTTT-----------------------IG Q2L882_HUMAN Q2L882_HUMAN MYRIYDMENVLLGLFSTIHDSIQYVQKNAGKLTTT-----------------------IG Q2L880_HUMAN Q2L880_HUMAN MYRIYDMENVLLGLFSTIHDSIQYVQKNAGKLTTTETEKKIWHFKYPIFFLCIGLDLQIG Q53H15_HUMAN Q53H15_HUMAN MYRIYDMENVLLGLFSTIHDSIQYVQKNAGKLTTT-----------------------IG Q8IYG2_HUMAN Q8IYG2_HUMAN MYRIYDMENVLLGLFSTIHDSIQYVQKNAGKLTTT-----------------------IG GPC3_HUMAN GPC3_HUMAN MYRIYDMENVLLGLFSTIHDSIQYVQKNAGKLTTT-----------------------IG MATCH CONSENSUS M???YD?E?VLL???????D??????????KL????????????????????????????

Q1L879_DANRE Q1L879_DANRE KVCGSLTESVSSTPANSTLGSLTPSVNPSLELQTSNTSSSHTTLPDTGNQHEHIALKRRE Q4SHZ8_TETNG Q4SHZ8_TETNG KLCGSLSGRSAQAVSPQQGSSRE---SIPLKTLVRGSG-------------DSLAIKRRD Q4T2U3_TETNG Q4T2U3_TETNG ------------------------------------------------------------ Q6V9Y8_DANRE Q6V9Y8_DANRE GMCVHAPPRVSRAVPVSAEHTSASTVNHNRPPMNFDPD-------------ETLFGRRRE A7MB84_BOVIN A7MB84_BOVIN KICGRPVRTPTQSPRCSFDGSKE---KHGMKISIRNGE-------------ETLANRRKE GPC5_HUMAN GPC5_HUMAN RICGRPVRTPTQSPRCSFDQSKE---KHGMKTTTRNSE-------------ETLANRRKE GPC5_MOUSE GPC5_MOUSE TICGHPVRTPTQSPRCTFDPSKE---KHGMKISARNGE-------------ETLANRRKE A9ULF4_XENTR A9ULF4_XENTR KLCSPSKQRISRSVHNKREFFIN---KK----------------------------KKKK GPC3_RAT GPC3_RAT KLCAHSQQRQYRSAYYPEDLFID---KKVLKVARVEHE-------------ETLSSRRRE Q3TX35_MOUSE Q3TX35_MOUSE KLCAHSQQRQYRSAYYPEDLFID---KKILKVAHVEHE-------------ETLSSRRRE Q3TWB2_MOUSE Q3TWB2_MOUSE KLCAHSQQRQYRSAYYPEDLFID---KKILKVAHVEHE-------------ETLSSRRRE GPC3_MOUSE GPC3_MOUSE KLCAHSQQRQYRSAYYPEDLFID---KKILKVAHVEHE-------------ETLSSRRRE Q9QZF1_MOUSE Q9QZF1_MOUSE KLCAHSQQRQYRSAYYPEDLFID---KKILKVAHVEHE-------------ETLSSRRRE B1ATR5_MOUSE B1ATR5_MOUSE KLCAHSQQRQYRSAYYPEDLFID---KKILKVAHVEHE-------------ETLSSRRRE Q3ZBZ6_BOVIN Q3ZBZ6_BOVIN KLCAHSQQRQYRSAYYPEDLFID---KKVLKVARVERE-------------ETLSSRRRE Q2Q1N3_CEREL Q2Q1N3_CEREL ------------------------------------------------------------ GPC3_PANTR GPC3_PANTR KLCAHSQQRQYRSAYYPEDLFID---KKVLKVARVEHE-------------ETLSSRRRE B4DTD8_HUMAN B4DTD8_HUMAN KLCAHSQQRQYRSAYYPEDLFID---KKVLKVAHVEHE-------------ETLSSRRRE Q2L882_HUMAN Q2L882_HUMAN KLCAHSQQRQYRSAYYPEDLFID---KKVLKVAHVEHE-------------ETLSSRRRE Q2L880_HUMAN Q2L880_HUMAN KLCAHSQQRQYRSAYYPEDLFID---KKVLKVAHVEHE-------------ETLSSRRRE Q53H15_HUMAN Q53H15_HUMAN KLCAHSQQRQYRSAYYPEDLFID---KKVLKVAHVEHE-------------ETLSSRRRE Q8IYG2_HUMAN Q8IYG2_HUMAN KLCAHSQQRQYRFAYYPEDLFID---KKVLKVAHVEHE-------------ETLSSRRRE GPC3_HUMAN GPC3_HUMAN KLCAHSQQRQYRSAYYPEDLFID---KKVLKVAHVEHE-------------ETLSSRRRE MATCH CONSENSUS ??C????????????????????????????????????????????????E?L???R?E

Q1L879_DANRE Q1L879_DANRE FMGYIQRYKSFFSNLPEMLCEGEVVMDENT-CWSGEDVVESYTGHVVGNGLQAQKHNPEI Q4SHZ8_TETNG Q4SHZ8_TETNG FLNSLRPCRTHYGGLADHLCMSELASGDGLSCWNGIDAVKRYLKRAKRDG---------- Q4T2U3_TETNG Q4T2U3_TETNG ------------------------------------------------------------ Q6V9Y8_DANRE Q6V9Y8_DANRE FISGLRGFSQFYSGLGEALCSKEPTSLNSSLCWNGQEMTDKFPGPGLK---RVHPHGSES A7MB84_BOVIN A7MB84_BOVIN FINSLRLYRTFYGGLADQLCANELDAADGLPCWNGEDIVKSYTQRVVGNGIKAQSGNPEV GPC5_HUMAN GPC5_HUMAN FINSLRLYRSFYGGLADQLCANELAAADGLPCWNGEDIVKSYTQRVVGNGIKAQSGNPEV GPC5_MOUSE GPC5_MOUSE FINSLRLHGSFYGGLADQLCVNELAAPEGRPCWNGEEIVKSYAQRVVGNGIKAQSANPEV A9ULF4_XENTR A9ULF4_XENTR ------------------------------------------------------------ GPC3_RAT GPC3_RAT LIQKLKSFISFYSALPGYICSHSPVAENDTLCWNGQELVERYSQKAARNGMKNQFNLHEL Q3TX35_MOUSE Q3TX35_MOUSE LIQKLKSFINFYSALPGYICSHSPVAENDTLCWNGQELVERYSQKAARNGMKNQFNLHEL Q3TWB2_MOUSE Q3TWB2_MOUSE LIQKLKSFINFYSALPGYICSHSPVAENDTLCWNGQELVERYSQKAARNGMKNQFNLHEL GPC3_MOUSE GPC3_MOUSE LIQKLKSFINFYSALPGYICSHSPVAENDTLCWNGQELVERYSQKAARNGMKNQFNLHEL Q9QZF1_MOUSE Q9QZF1_MOUSE LIQKLKSFINFYSALPGYICSHSPVAENDTLCWNGQELVERYSQKAARNGMKNQFNLHEL B1ATR5_MOUSE B1ATR5_MOUSE LIQKLKSFINFYSALPGYICSHSPVAENDTLCWNGQELVER------------------- Q3ZBZ6_BOVIN Q3ZBZ6_BOVIN LIQKLKSFISFYSALPGYICSHSPVAENDTLCWNGQELVERYSQKAARNGMKNQFNLHEL Q2Q1N3_CEREL Q2Q1N3_CEREL ------------------------------------------------------------ GPC3_PANTR GPC3_PANTR LIQKLKSFISFYSALPGYICSHSPVAENDTLCWNGQELVERYSQKAARNGMKNQFNLHEL B4DTD8_HUMAN B4DTD8_HUMAN LIQKLKSFISFYSALPGYICSHSPVAENDTLCWNGQELVERYSQKAARNGMKNQFNLHEL Q2L882_HUMAN Q2L882_HUMAN LIQKLKSFISFYSALPGYICSHSPVAENDTLCWNGQELMERYSQKAARNGMKNQFNLHEL Q2L880_HUMAN Q2L880_HUMAN LIQKLKSFISFYSALPGYICSHSPVAENDTLCWNGQELMERYSQKAARNGMKNQFNLHEL Q53H15_HUMAN Q53H15_HUMAN LIQKLKSFISFYSALPGYICSHSPVAENDTLCWNGQELMERYSQKAARNGMKNQFNLHEL Q8IYG2_HUMAN Q8IYG2_HUMAN LIQKLKSFISFYSALPGYICSHSPVAENDTLCWNGQELVERYSQKAARNGMKNQFNLHEL GPC3_HUMAN GPC3_HUMAN LIQKLKSFISFYSALPGYICSHSPVAENDTLCWNGQELVERYSQKAARNGMKNQFNLHEL MATCH CONSENSUS ????L?????FY??L????C???????????CWNG?????????????????????????

Q1L879_DANRE Q1L879_DANRE KVKTANPVLVSVKEMLEHFNQEM---------WATT----------------GLGTGGTD Q4SHZ8_TETNG Q4SHZ8_TETNG ---SIKPCIIISVEK--------------------------------------------- Q4T2U3_TETNG Q4T2U3_TETNG ------------------------------------------------------------ Q6V9Y8_DANRE Q6V9Y8_DANRE KQKTPEPVISQIIDKLKHINQLLRMVTLPEKRWRARQGGGGARRNPSGPGQTDEDEEG-- A7MB84_BOVIN A7MB84_BOVIN KVKGTNPVINQIIDKLRHVIQLLQGRSPKPTKWE-L----------------HMGSGGGT GPC5_HUMAN GPC5_HUMAN KVKGIDPVINQIIDKLKHVVQLLQGRSPKPDKWELL----------------QLGSGGGM GPC5_MOUSE GPC5_MOUSE RVRGTDPVVNQIIDKLKHVIQLLRGRSPKPNKWELL----------------QPGSGGGM A9ULF4_XENTR A9ULF4_XENTR ------------------------------------------------------------ GPC3_RAT GPC3_RAT KMKGPEPVVSQIIDKLKHINQLLRTMSVPKGKVVDK----------------SLDEEG-- Q3TX35_MOUSE Q3TX35_MOUSE KMKGPEPVVSQIIDKLKHINQLLRTMSVPKGKVLDK----------------SLDEEG-- Q3TWB2_MOUSE Q3TWB2_MOUSE KMKGPEPVVSQIIDKLKHINQLLRTMSVPKGKVLDK----------------SLDEEG-- GPC3_MOUSE GPC3_MOUSE KMKGPEPVVSQIIDKLKHINQLLRTMSVPKGKVLDK----------------SLDEEG-- Q9QZF1_MOUSE Q9QZF1_MOUSE KMKGPEPVVSQIIDKLKHINQLLRTMSVPKGKVLDK----------------SLDEEG-- B1ATR5_MOUSE B1ATR5_MOUSE ------------------------------------------------------------ Q3ZBZ6_BOVIN Q3ZBZ6_BOVIN KMKGPEPVVSQIIDKLKHINQLLRTMSVPKGRVLDK----------------NLDEEG-- Q2Q1N3_CEREL Q2Q1N3_CEREL ------------------------------------------------------------ GPC3_PANTR GPC3_PANTR KMKGPEPVVSQIIDKLKHINQLLRTMSVPKGRVLDK----------------NLDEEG-- B4DTD8_HUMAN B4DTD8_HUMAN KMKGPEPVVSQIIDKLKHINQLLRTMSMPKGRVLDK----------------NLDEEG-- Q2L882_HUMAN Q2L882_HUMAN KMKGPEPVVSQIIDKLKHINQLLRTMSMPKGRVLDK----------------NLDEEG-- Q2L880_HUMAN Q2L880_HUMAN KMKGPEPVVSQIIDKLKHINQLLRTMSMPKGRVLDK----------------NLDEEG-- Q53H15_HUMAN Q53H15_HUMAN KMKGPEPVVSQIIDKLKHINQLLRTMSMPKGRVLDK----------------NLDEEG-- Q8IYG2_HUMAN Q8IYG2_HUMAN KMKGPEPVVSQIIDKLKHINQLLRTMSMPKGRVLDK----------------NLDEEG-- GPC3_HUMAN GPC3_HUMAN KMKGPEPVVSQIIDKLKHINQLLRTMSMPKGRVLDK----------------NLDEEG-- MATCH CONSENSUS ??????P?????????????????????????????????????????????????????

Q1L879_DANRE Q1L879_DANRE VKESSSAEGSGECDDEDGCQGSGRGDERGK------------------------------ Q4SHZ8_TETNG Q4SHZ8_TETNG ------------------------------------------------------------ Q4T2U3_TETNG Q4T2U3_TETNG ------------------------------------------------------------ Q6V9Y8_DANRE Q6V9Y8_DANRE -------LESGDC-DDEDECTGVSGLGPPPRRKRLRIFADLADNLAIDDLTLHELLLTPR A7MB84_BOVIN A7MB84_BOVIN VE-----QVSGDCDDEDGCGGSGSGEVKRTLKITDFFPSIKIFSDESALRIGWPKYWSFS GPC5_HUMAN GPC5_HUMAN VE-----QVSGDCDDEDGCGGSGSGEVKRTLKITDWMPDDMNFSD-VKQIHQTDTGSTLD GPC5_MOUSE GPC5_MOUSE LE-----NSSGDCDDEDGCGGSGSGEVKRTLKITNWMPDSMNFSD--VKQVHRADHGSTL A9ULF4_XENTR A9ULF4_XENTR ------------------------------------------------------------ GPC3_RAT GPC3_RAT -------LESGDCGDDEDECIGSSGDGMMKVKNQLRFLAELAYDLDVDDAPGNKQHGNQK Q3TX35_MOUSE Q3TX35_MOUSE -------LESGDCGDDEDECIGSSGDGMVKVKNQLRFLAELAYDLDVDDAPGNKQHGNQK Q3TWB2_MOUSE Q3TWB2_MOUSE -------LESGDCGDDEDECIGSSGDGMVKVKNQLRFLAELAYDLDVDDAPGNKQHGNQK GPC3_MOUSE GPC3_MOUSE -------LESGDCGDDEDECIGSSGDGMVKVKNQLRFLAELAYDLDVDDAPGNKQHGNQK Q9QZF1_MOUSE Q9QZF1_MOUSE -------LESGDCGDDEDECIGSSGDGMVKVKNQLRFLAELAYDLDVDDAPGNKQHGNQK B1ATR5_MOUSE B1ATR5_MOUSE ------------------------------------------------------------ Q3ZBZ6_BOVIN Q3ZBZ6_BOVIN -------LESGDCGDDEDECIGGSGDGMMKVKNQLRFLAELAYDLDVDDAPGSKQHVNQK Q2Q1N3_CEREL Q2Q1N3_CEREL ------------------------------------------------------------ GPC3_PANTR GPC3_PANTR -------FESGDCGDDEDECIGGSGDGMMKVKNQLRFLAELAYDLDVDDAPGSNQQATPK B4DTD8_HUMAN B4DTD8_HUMAN -------FESGDCGDDEDECIGGSGDGMIKVKNQLRFLAELAYDLDVDDAPGNSQQATPK Q2L882_HUMAN Q2L882_HUMAN -------FESGDCGDDEDECIGGSGDGMIKVKNQLRFLAELAYDLDVDDAPGNSQQATPK Q2L880_HUMAN Q2L880_HUMAN -------FESGDCGDDEDECIGGSGDGMIKVKNQLRFLAELAYDLDVDDAPGNSQQATPK Q53H15_HUMAN Q53H15_HUMAN -------FESGDCGDDEDECIGGSGDGMIKVKNQLRFLAELAYDLDVDDAPGNSQQATPK Q8IYG2_HUMAN Q8IYG2_HUMAN -------FESGDCGDDEDECIGGSGDGMIKVKNQLRFLAELAYDLDVDDAPGNSQQATPK GPC3_HUMAN GPC3_HUMAN -------FESGDCGDDEDECIGGSGDGMIKVKNQLRFLAELAYDLDVDDAPGNSQQATPK MATCH CONSENSUS ????????????????????????????????????????????????????????????

Q1L879_DANRE Q1L879_DANRE ------------------------------------------------------------ Q4SHZ8_TETNG Q4SHZ8_TETNG ------------------------------------------------------------ Q4T2U3_TETNG Q4T2U3_TETNG ------------------------------------------------------------ Q6V9Y8_DANRE Q6V9Y8_DANRE LATDAHGG-------------SSIPGAAHVPTAAFIFTITIIIFI-TLGLQ--------- A7MB84_BOVIN A7MB84_BOVIN FNSPSSEHPGLISFGMAWLDLLAVHGTLKSLLQRHSSKASILWCSAFFIVH--------- GPC5_HUMAN GPC5_HUMAN TTGAGCAVA---------------TESMTFTLISVVMLLPGIW----------------- GPC5_MOUSE GPC5_MOUSE DTTSTGCAS----------------GTESMALPLMGTLMFLPWLW--------------- A9ULF4_XENTR A9ULF4_XENTR ------------------------------------------------------------ GPC3_RAT GPC3_RAT DNEITTSHS---------------VGNMPSPLKILISVAIYVACF-FSWCTDLPCPCLCC Q3TX35_MOUSE Q3TX35_MOUSE DNEITTSHS---------------VGNMPSPLKILISVAIYVACF-FFLVH--------- Q3TWB2_MOUSE Q3TWB2_MOUSE DNEITTSHS---------------VGNMPSPLKILISVAIYVACF-FFLVH--------- GPC3_MOUSE GPC3_MOUSE DNEITTSHS---------------VGNMPSPLKILISVAIYVACF-FFLVH--------- Q9QZF1_MOUSE Q9QZF1_MOUSE DNEITTSHS---------------VGNMPSPLKILISVAIYVACL-FFLVH--------- B1ATR5_MOUSE B1ATR5_MOUSE ------------------------------------------------------------ Q3ZBZ6_BOVIN Q3ZBZ6_BOVIN DNEIVASHN---------------LGNGHPPLKLLTSLAISVLCF-FLLVH--------- Q2Q1N3_CEREL Q2Q1N3_CEREL ------------------------------------------------------------ GPC3_PANTR GPC3_PANTR DNEISTFHN---------------LGNVHSPLKLLTSMAISVVCF-FFLVH--------- B4DTD8_HUMAN B4DTD8_HUMAN DNEISTFHN---------------LGNVHSPLKLLTSMAISVVCF-FFLVH--------- Q2L882_HUMAN Q2L882_HUMAN DNEISTFHN---------------LGNVHSPLKLLTSMAISVVCF-FFLVH--------- Q2L880_HUMAN Q2L880_HUMAN DNEISTFHN---------------LGNVHSPLKLLTSMAISVVCF-FFLVH--------- Q53H15_HUMAN Q53H15_HUMAN DNEISTFHN---------------LGNVHSPLKLLTSMAISVVCF-FFLVH--------- Q8IYG2_HUMAN Q8IYG2_HUMAN DNEISTFHN---------------LGNVHSPLKLLTSMAISVVCF-FFLVH--------- GPC3_HUMAN GPC3_HUMAN DNEISTFHN---------------LGNVHSPLKLLTSMAISVVCF-FFLVH--------- MATCH CONSENSUS ????????????????????????????????????????????????????????????

Q1L879_DANRE Q1L879_DANRE --------- Q4SHZ8_TETNG Q4SHZ8_TETNG --------- Q4T2U3_TETNG Q4T2U3_TETNG --------- Q6V9Y8_DANRE Q6V9Y8_DANRE --------- A7MB84_BOVIN A7MB84_BOVIN --------- GPC5_HUMAN GPC5_HUMAN --------- GPC5_MOUSE GPC5_MOUSE --------- A9ULF4_XENTR A9ULF4_XENTR --------- GPC3_RAT GPC3_RAT PAAPCGPPT Q3TX35_MOUSE Q3TX35_MOUSE --------- Q3TWB2_MOUSE Q3TWB2_MOUSE --------- GPC3_MOUSE GPC3_MOUSE --------- Q9QZF1_MOUSE Q9QZF1_MOUSE --------- B1ATR5_MOUSE B1ATR5_MOUSE --------- Q3ZBZ6_BOVIN Q3ZBZ6_BOVIN --------- Q2Q1N3_CEREL Q2Q1N3_CEREL --------- GPC3_PANTR GPC3_PANTR --------- B4DTD8_HUMAN B4DTD8_HUMAN --------- Q2L882_HUMAN Q2L882_HUMAN --------- Q2L880_HUMAN Q2L880_HUMAN --------- Q53H15_HUMAN Q53H15_HUMAN --------- Q8IYG2_HUMAN Q8IYG2_HUMAN --------- GPC3_HUMAN GPC3_HUMAN --------- MATCH CONSENSUS ?????????


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