Alignment of the gene Family HBG006198 of HOVERGEN

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Threshold: 50% 80% 100%
Size: Bigger Smaller Normal
Isoforms are ON
Q4RYA2_TETNG Q4RYA2_TETNG ------------------------------------------------------------ Q6P938_DANRE Q6P938_DANRE MRDGLTGLCIGIILL--------------LNGGLVVMRRQDSSSALGSIFRTR---CAAR Q9IAR4_DANRE Q9IAR4_DANRE MRDGLTGLCIGIILL--------------LNGGLVVMRRQDSSSALGSIFRTR---CAAR Q2HXL4_ORYLA Q2HXL4_ORYLA MFSRSLKLCASLCL--WITAL--------TSPGSVSARKQDDSFFTASIYRAR---CASR Q4S0E8_TETNG Q4S0E8_TETNG MAGSGLNSWANILLSASTTGM--------LSHSKISSSMNQGGFLRGEMLRIMDPWCGAR A9JRI8_XENTR A9JRI8_XENTR MWLREPGCRSLLTFILWITLVWGSRCAATATAAAASSRKQDESLSAQSIYRAR---CTSR B2RPF8_HUMAN B2RPF8_HUMAN MVPGVPG--AVLTLCLWLAAS--SGCLA-AGPGAAAARRLDESLSAGSVQRAR---CASR KALM_HUMAN KALM_HUMAN MVPGVPG--AVLTLCLWLAAS--SGCLA-AGPGAAAARRLDESLSAGSVQRAR---CASR KALM_CHICK KALM_CHICK MVRRAPG--ASLALLLWVTAV--S-GSP-AGPGAATARRQDEAFST-----AR---CTSR KALM_COTJA KALM_COTJA MVRRAPG--ASLALLLWVTAV--S-CSP-AGPGAATARRQDEAFST-----AR---LTSR Q1MT36_DANRE Q1MT36_DANRE LLLRNLCCFLLCCVF-----------------EVSVARRTEEAESLEKMESAR---CVSR Q9IAR3_DANRE Q9IAR3_DANRE LLLRNLCCCLLCCVF-----------------EVSVARRTEEAESLEKMESAR---CVSR Q2HXL3_ORYLA Q2HXL3_ORYLA SVLRVGS------VLLWAV----------LAVSRARRSPTEPEEVQEHINSAR---CTSR Q4RJ25_TETNG Q4RJ25_TETNG ------------------------------------------------------------ MATCH CONSENSUS ???????????????????????????????????????????????????????????R

Q4RYA2_TETNG Q4RYA2_TETNG ----------------QNNGSLGWCQADKQCSKCLEPCKESWGMDRKINCNQFCERAFPR Q6P938_DANRE Q6P938_DANRE CLSLHSTRIALSPRHFQSNGSLGWCQSHKQCAKCLEPCKDSWEL-KDGPCRDLCEHAFPK Q9IAR4_DANRE Q9IAR4_DANRE CLSLHSTRIALSPRHFQSNGSLGWCQSHKQCAKCLEPCKDSWEL-KDGPCRDLCEHAFPK Q2HXL4_ORYLA Q2HXL4_ORYLA CLSLHITRISAFFKHSQNNGSLVWCQNHKQCSKCLEPCKESWDL-KENQCQDLCEPLFPK Q4S0E8_TETNG Q4S0E8_TETNG ITSSAPSSDIRTFRET-----------------CLEPCKESWDL-KENQCQDLCEPLFPK A9JRI8_XENTR A9JRI8_XENTR CLSLHITRISAYFKHFQNNGSLIWCQNHKQCSKCLEPCKETWDL-RKNNCHNLCEPLFPK B2RPF8_HUMAN B2RPF8_HUMAN CLSLQITRISAFFQHFQNNGSLVWCQNHKQCSKCLEPCKESGDL-RKHQCQSFCEPLFPK KALM_HUMAN KALM_HUMAN CLSLQITRISAFFQHFQNNGSLVWCQNHKQCSKCLEPCKESGDL-RKHQCQSFCEPLFPK KALM_CHICK KALM_CHICK CLSLQITRISAFFKHFQNNGSLAWCQNHKQCSKCLEPCKESWDL-KKNHCQSFCEPLFPK KALM_COTJA KALM_COTJA CLSLQITRISAFFKHFQDNGSLAWCQNYKQCSKCLEPCKESWDL-KRNHCQSFCEPLFPK Q1MT36_DANRE Q1MT36_DANRE CLTLHITQITAAFRHLQNDRVLGWCENHRRCSQCLQPCKELWET-RRALSPKTCE----- Q9IAR3_DANRE Q9IAR3_DANRE CLTLHITQITAAFRHLQNDRVLGWCENHRRCSQCLQPCKELWET-RRALSPKTCE----- Q2HXL3_ORYLA Q2HXL3_ORYLA CLSLHMTQITAAFRHIQSDEVLVWCENHRRCAQCLQPCEELWET-RTVLPPKACE----- Q4RJ25_TETNG Q4RJ25_TETNG ---------------------------------------------------------LPQ MATCH CONSENSUS ????????????????Q????L?WC?????C??CL?PCK??????????????CE?????

Q4RYA2_TETNG Q4RYA2_TETNG KNWECVTSCEFLQSALAVKQGTCLPPERASGFAAACVEGCDHDRECSAQKKCCFNGCGHT Q6P938_DANRE Q6P938_DANRE RHGECVTSCEFLRSVMVVKQGDCPPPERASGFAAACVEGCEEDGECSGQKKCCPNGCGHT Q9IAR4_DANRE Q9IAR4_DANRE RHGECVTSCEFLRSVMVVKQGDCPPPERASGFAAACVEGCEEDGECSGQKKCCPNGCGHT Q2HXL4_ORYLA Q2HXL4_ORYLA KHYECLTSCEFLKSVEGVKQGDCPAPEKASGFAAACVESCEEDGECSAVKKCCSNGCGHT Q4S0E8_TETNG Q4S0E8_TETNG KHYECLTSCEFLKSVEGVKQGDCPAPEKASGFAAACVESCEEDSECSAVKKCCSNGCGHT A9JRI8_XENTR A9JRI8_XENTR KHYECLTSCEFLKSVLSVKQGDCPAPEKASGFAAACVESCDADNECSGVKKCCSNGCGHT B2RPF8_HUMAN B2RPF8_HUMAN KSYECLTSCEFLKYILLVKQGDCPAPEKASGFAAACVESCEVDNECSGVKKCCSNGCGHT KALM_HUMAN KALM_HUMAN KSYECLTSCEFLKYILLVKQGDCPAPEKASGFAAACVESCEVDNECSGVKKCCSNGCGHT KALM_CHICK KALM_CHICK KNYECLTSCEFLKYILSVKQGDCPAPEKASGFAAACVESCEADSECSGVKKCCSNGCGHT KALM_COTJA KALM_COTJA KNYECLTSCEFLKYILSVKQGDCPAPEKASGFAAACFESCEADSECSGVKKCCSNGCGHT Q1MT36_DANRE Q1MT36_DANRE -HHECVTSAEFLRSLRVQKQGDCPPAQRASGFAAACVESCARDRECSGVKKCCSNGCGHT Q9IAR3_DANRE Q9IAR3_DANRE -HHECVTSAEFLRSLRVQKQGDCPPAQRASGFAAACVESCAQDRECSGVKKCCSNGCGHT Q2HXL3_ORYLA Q2HXL3_ORYLA KQTECMTSREFLASLRSSRQGDCPPPQRATGFAAACVESCSSDQHCPSSRKCCFNGCGHT Q4RJ25_TETNG Q4RJ25_TETNG KQTECVTSREFLTSLRSSRQGDCPPPQRAAGFAAACVESCSSDQHCPSPRKCCSNGCGHT MATCH **:** *** :** * ..::*:******.*.* * .*.. :*** ****** CONSENSUS ???EC?TS?EFL??????KQGDCP?P??ASGFAAACVE?C??D?ECS??KKCC?NGCGHT

Q4RYA2_TETNG Q4RYA2_TETNG CQAPKDLYKSVPLKPRKELSLRELPSGQLEVRWSSRFNISAEPVVYVLQRRWNFGIQPSE Q6P938_DANRE Q6P938_DANRE CQSPKNLYRGAPLKPRKELVFEELESGVLEVRWSSKFNVSAEPVLNVLQRRWNYGIHPSE Q9IAR4_DANRE Q9IAR4_DANRE CQSPKNLYRGAPLKPRKELVFEELESGVLEVRWSSKFNVSAEPVLNVLQRRWNYGIHPSE Q2HXL4_ORYLA Q2HXL4_ORYLA CQLPKNLYKGVPLKPRKELVFLEHPSGQLEIHWSSKFNISVEPVLYVVQRRWNYGIHPSE Q4S0E8_TETNG Q4S0E8_TETNG CQLPKNLYKGVPLKPRKELVFLEQASGQLEIRWSSKFNISVEPVLYVVQRRWNYGIHPSE A9JRI8_XENTR A9JRI8_XENTR CQVPKNLYKGVPLKPRKELTFDEPQPGHLDIKWSSKFNISVEPVIYVVQRRWNYGIHPSE B2RPF8_HUMAN B2RPF8_HUMAN CQVPKTLYKGVPLKPRKELRFTELQSGQLEVKWSSKFNISIEPVIYVVQRRWNYGIHPSE KALM_HUMAN KALM_HUMAN CQVPKTLYKGVPLKPRKELRFTELQSGQLEVKWSSKFNISIEPVIYVVQRRWNYGIHPSE KALM_CHICK KALM_CHICK CQVPKNLYKGVPLKPRKELKFIELQSGDLEVKWSSKFNISIEPVIYVVQRRWNQGIHPSE KALM_COTJA KALM_COTJA CQVPKNLYKGVPLKPRKELKFIELQSGDLEVKWSSKFNISIEPVIYVVQRRWNQGIHPSE Q1MT36_DANRE Q1MT36_DANRE CQSPANLFKGVPLKPRRDISFSEDHQGHVKVTWMSKFNVSVEPVLYVLQRRWNHGIHPSE Q9IAR3_DANRE Q9IAR3_DANRE CQSPANLFKGVPLKPRRDISFSEDHQGHVKVTWMSKFNVSVEPVLYVLQRRWNHGIHPSE Q2HXL3_ORYLA Q2HXL3_ORYLA CQAPANLYKGVPLKPRREMSFTEDSEGHVKVGWVSKFNVSMEPVVYLLESRWNIGIHPSE Q4RJ25_TETNG Q4RJ25_TETNG CQAPSNLYKGVPLKPRRDMNFEEDPEGHLKVTWVSKFNISMEPVVYILQSRWNIGIHPSE MATCH ** * *::..*****::: : * * :.: * *:**:* ***: ::: *** **:*** CONSENSUS CQ?P??LYKGVPLKPR????F?E???G?????W?SKFN?S?EPV?YV?QRRWN?GIHPSE

Q4RYA2_TETNG Q4RYA2_TETNG DSATSWQVVAQTTEQGARLSDIRPGRWYQFRVAATNTRGTRGFTTPSRHIHASRDPANPP Q6P938_DANRE Q6P938_DANRE DGATEWQVVARTSEERVWLTDIRPGRWYQFRVAAVNVHGTRGYTTPSRHFRSSKDPPPPP Q9IAR4_DANRE Q9IAR4_DANRE DGATEWQVVARTSGERVWLTDIRPGRWYQFRVAAVNVHGTRGYTTPSRHFRSSKDPPPPP Q2HXL4_ORYLA Q2HXL4_ORYLA DDATEWQTVAQTAEERIQLADTRASRWYQFRVAAVNVHGTRGFTAPSKHFRSSRDPAAPP Q4S0E8_TETNG Q4S0E8_TETNG DEATDWETVAQTFGIGFDGGGARPTGRHQGQQMVPVQSGCSQCSRDPRLHRTQQTLPVLQ A9JRI8_XENTR A9JRI8_XENTR DDASNWQTMAQITDERVQLSDIRPSRWYQFRVAAVNVHGTRGFTAPSKHFRSSKDPSPPP B2RPF8_HUMAN B2RPF8_HUMAN DDATHWQTVAQTTDERVQLTDIRPSRWYQFRVAAVNVHGTRGFTAPSKHFRSSKDPSAPP KALM_HUMAN KALM_HUMAN DDATHWQTVAQTTDERVQLTDIRPSRWYQFRVAAVNVHGTRGFTAPSKHFRSSKDPSAPP KALM_CHICK KALM_CHICK DDATNWQTVAQTTDERVQLSDIRASRWYQFRVAAVNVHGTRGFTAPSKHFRSSKDPSAPP KALM_COTJA KALM_COTJA DDATNWQTVAQTTDERVQLSDIRASRWYQFRVAAVNVHGTRGFTAPSKHFRSSKDPSAPP Q1MT36_DANRE Q1MT36_DANRE DEASAWQTVLMTMEDRSVLKDIRPHRWYQFRVSAVNSQGTRGFTTPSKHFFSVRDPLPPE Q9IAR3_DANRE Q9IAR3_DANRE DEATAWQTVLMTMEDRSVLKDIRPHRWYQFRVSAVNSQGTRGFTTPSKHFFSVRDPLPPE Q2HXL3_ORYLA Q2HXL3_ORYLA DHASPWSAVAMTLSEEVLLTDLRPQRWYQFRVAAVNSQGSRGFTTPSKHYISSKDPSPPE Q4RJ25_TETNG Q4RJ25_TETNG DHASPWTTVAMVLSEDVVLSDLRPQRWYQFRVAAINSHGSRGFTTPSKHYMSSKDPSAPE MATCH * *: * .: . *. :* : . * : .: : : CONSENSUS D?A??W??VA?T??????L?D?R??RWYQFRV?A?N??G?RG?T?PS?H??S??DP??P?

Q4RYA2_TETNG Q4RYA2_TETNG APAELRVANLSFGPGR----------------VVSARLQWTMPPDLDVPVHHYKVSW--- Q6P938_DANRE Q6P938_DANRE APSDLHVSDMTFGADH----------------SASVRLSWSISADLDIPVNHYKLSW--- Q9IAR4_DANRE Q9IAR4_DANRE APSDLHVSDMTFGADH----------------SASVRLSWSISADLDIPVNHYKLSW--- Q2HXL4_ORYLA Q2HXL4_ORYLA SAANLHVTNMSLADDG----------------LVTARLNWTLPHEPDIPIHHYKVFW--- Q4S0E8_TETNG Q4S0E8_TETNG RPSSLRITRLTPGEEG----------------SVTARLNWTLPEEPDIPIHHYKVFW--- A9JRI8_XENTR A9JRI8_XENTR APTNLRISNLTTNNEG----------------TVSVRITWDLPEEPDIPVHHYKVFW--- B2RPF8_HUMAN B2RPF8_HUMAN APANLRLANSTVNSDG----------------SVTVTIVWDLPEEPDIPVHHYKVFW--- KALM_HUMAN KALM_HUMAN APANLRLANSTVNSDG----------------SVTVTIVWDLPEEPDIPVHHYKVFW--- KALM_CHICK KALM_CHICK APSNIRIANISANNDG----------------TVNVMITWDLPEEPDIPVHHYKVFW--- KALM_COTJA KALM_COTJA APSNIRIANISANNDG----------------TVNVMITWDLPEEPDIPVHHYKVFW--- Q1MT36_DANRE Q1MT36_DANRE TPQNARTANQTLHPDG----------------TVSVLVLWETPRESDLVVHHHKVTW--- Q9IAR3_DANRE Q9IAR3_DANRE TPQNARTANQTLHPDG----------------TVSVLVLWETPRESDLVVHHYKVTW--- Q2HXL3_ORYLA Q2HXL3_ORYLA PPMNIRVSNQTLNWAGLQLMPKVTERSSESGTTVAVLLNWEPPSEGDLLIRNYRITWMPL Q4RJ25_TETNG Q4RJ25_TETNG PPVNVR------------------------------------------------------ MATCH . . : CONSENSUS ?P?????????????????????????????????????W??????D????HYK??W???

Q4RYA2_TETNG Q4RYA2_TETNG ------------------------SWSHSGQFAASPLNKKRKI-VQ--QNHIDLDNMRSN Q6P938_DANRE Q6P938_DANRE ------------------------S---SSDHNLPPKLKKRET-VNGDSTYAELDDLREN Q9IAR4_DANRE Q9IAR4_DANRE ------------------------S---SSDHNLPPKLKKRET-VNGDSTYAELDDLREN Q2HXL4_ORYLA Q2HXL4_ORYLA ------------------------SWTVPTKSMVPSKKKQRKT-INGAQNWLDLEGLQQN Q4S0E8_TETNG Q4S0E8_TETNG ------------------------SWTVPTRSMVPSKKKRRKT-TKGAQSWVDLEGLQQN A9JRI8_XENTR A9JRI8_XENTR ------------------------SWTANRKSVVPAKKKRRKT-TEGSQNSVALDGLQAN B2RPF8_HUMAN B2RPF8_HUMAN ------------------------SWMVSSKSLVPTKKKRRKT-TDGFQNSVILEKLQPD KALM_HUMAN KALM_HUMAN ------------------------SWMVSSKSLVPTKKKRRKT-TDGFQNSVILEKLQPD KALM_CHICK KALM_CHICK ------------------------SWT-YSKYVIPAKKKRRKI-TDGPQNYVVLEGLQPN KALM_COTJA KALM_COTJA ------------------------SWT-YSKYVIPAKKKRRKI-TDGPQNYVVLEGLQPN Q1MT36_DANRE Q1MT36_DANRE ------------------------S---PRGTPSSSQSRAGRV-TDGDVTQMELQGLQPN Q9IAR3_DANRE Q9IAR3_DANRE ------------------------S---PRGTPSSSQSRAGRV-TDGDVTQMELQGLQPN Q2HXL3_ORYLA Q2HXL3_ORYLA HVHTAHKHTHSLQANAQRLHKNKQKWPTNSHRQEQKKKESNTVLTAGAQNELWVQGLLPG Q4RJ25_TETNG Q4RJ25_TETNG -----------------------------------------------AQCELWLHGLLPA MATCH :. : CONSENSUS ????????????????????????S?????????????????????G??????L??L???

Q4RYA2_TETNG Q4RYA2_TETNG RTYSVEVQAVSFWGQTPLKGPRAIIHFSTQHSM---------SSHTGHI---FPVQLAIF Q6P938_DANRE Q6P938_DANRE GSYTVELQAVSYWGQVPLKSSKAILQFTTSQTQ-----------------------SDLE Q9IAR4_DANRE Q9IAR4_DANRE GSYTVELQAVSYWGQVPLKSSKAILQFTTSQTQ-----------------------SDLE Q2HXL4_ORYLA Q2HXL4_ORYLA SSYSVELQAITYWGQVRLKSPKSSLHFTTNQNN---------ESAKSML---KSKKDATS Q4S0E8_TETNG Q4S0E8_TETNG SSYTVELQAVTYWGQVRLKSSKASLQFSTSQNN---------ESVKSVL---KSKKEEIS A9JRI8_XENTR A9JRI8_XENTR SNYMVELQAITYWGQVRLKSGKVSLYFSTSPPS---------TSLDQIS---KISKMKTD B2RPF8_HUMAN B2RPF8_HUMAN CDYVVELQAITYWGQTRLKSAKVSLHFTSTHAT---------NNKEQLV---KTRKGGIQ KALM_HUMAN KALM_HUMAN CDYVVELQAITYWGQTRLKSAKVSLHFTSTHAT---------NNKEQLV---KTRKGGIQ KALM_CHICK KALM_CHICK SNYNVELQAVTRWGQIRLKSAKVSLHFSTAQDN---------RNNNEQTSAGKPPKGLVD KALM_COTJA KALM_COTJA SNYNVELQAVTRWGQIRLKSAKVSLHFSTTQDN---------RNNNEQTSVEKPPKGVVD Q1MT36_DANRE Q1MT36_DANRE TPYTAQIQAISYWGQNRLKSSRAHISFTTTSQN---------SA--------TSSNGEFS Q9IAR3_DANRE Q9IAR3_DANRE TPYTAQIQAISYWGQNRLKSSRAHVSFTTTSQN---------SA--------TSSNGEFS Q2HXL3_ORYLA Q2HXL3_ORYLA TPYSLSVQSVAYWGQKRLKSHRAQLVFTTIPNADGDFSNELPSSSSSLSPSSPSYPSVSQ Q4RJ25_TETNG Q4RJ25_TETNG SSYLLSVQTVAYWGQKRLKSPKLQMVFTTITQR--------------------------- MATCH * .:*::: *** **. : : *:: CONSENSUS ??Y????QA???WGQ??LKS??????F?T???????????????????????????????

Q4RYA2_TETNG Q4RYA2_TETNG KLRRMMHGAPRDDIMDVGMPFYQDGQLQVHVYWQKTLDPS----EYYLIHWGPEFCGHNQ Q6P938_DANRE Q6P938_DANRE PTVSPVFIKPQSDLLDVGTPFYQDGQLQVRVYWKKK-DPT---VNRYRVQWAPEFCSHNG Q9IAR4_DANRE Q9IAR4_DANRE PTVSPVFIKPQSDLLDVGTPFYQDGQLQVRVYWKKK-DPT---VNRYRVQWAPEFCSHNG Q2HXL4_ORYLA Q2HXL4_ORYLA PVGSTLAKRPSG-ALEVGTPFYQDGQLQVRVYWKKRGDPS---VSRYHVQWMPEYCNHNE Q4S0E8_TETNG Q4S0E8_TETNG LLSSTLAKRPSG-PLEVGTPFYQDSQLQVRVYWKNRGDPS---VTRYHVQWLPEYCSHNE A9JRI8_XENTR A9JRI8_XENTR ILAPPQRKRTAR-MLEIGAPFYQDNQLQVKVYWKKTEDSM---LGLYHVQWFPESCAHNE B2RPF8_HUMAN B2RPF8_HUMAN TQLPFQRRRPTR-PLEVGAPFYQDGQLQVKVYWKKTEDPT---VNRYHVRWFPEACAHNR KALM_HUMAN KALM_HUMAN TQLPFQRRRPTR-PLEVGAPFYQDGQLQVKVYWKKTEDPT---VNRYHVRWFPEACAHNR KALM_CHICK KALM_CHICK PYPTFQRRKPTR-FLKIGTPFYQDNQLQVKVYWKKT-DIN---MNQFQVHSLLESCVHND KALM_COTJA KALM_COTJA PYPTFQRRKPTR-FLKIGTPFYQDNQLQVKIYWKKS-GIN---MNQFQVHSLLESCTHND Q1MT36_DANRE Q1MT36_DANRE NELPVSHSSPSVLRLEAAAPHYHDNQLQVKVFWKSRVQESQKDSSSYILRWYPEVCSHNV Q9IAR3_DANRE Q9IAR3_DANRE NELPVSHSSPSVLRLEAAAPHYHDNQLQVKVFWKSRVQESQKDSSSYILRWYPEVCSHNV Q2HXL3_ORYLA Q2HXL3_ORYLA PDSPVNPVPSEKLRLEAAAPHYHDNQLQVKVYWKWPHHFRPKHQDLYILRWHPHTCINNV Q4RJ25_TETNG Q4RJ25_TETNG ------------------------------------GDSS--------HHYRPVVCL--- MATCH : * CONSENSUS ??????????????L????P?Y?D?QLQV?V?WK??????????????????PE?C?HN?

Q4RYA2_TETNG Q4RYA2_TETNG TKPMETI--TTQESFVTLRSLLFSCKYKVLLQPVSKRSPSLSQTTSFFTPSCALIRDKSP Q6P938_DANRE Q6P938_DANRE SRTQEKL--ITQENFASLPGLQFSCKYKVIIQPVGLKGRAQVESTTFYTPSCATIQSKSP Q9IAR4_DANRE Q9IAR4_DANRE SRTQGKL--ITQENFASLPGLQFSCKYKVIIQPVGLKGRTQVESTTFYTPSCATIQSKSP Q2HXL4_ORYLA Q2HXL4_ORYLA TRGPEKS--VTQENYINLPGLLFSCKYKVTVQLLKSKRRSKDESTTFLTPSCATIRSKTH Q4S0E8_TETNG Q4S0E8_TETNG TRGPEKS--VTQENYINLPGLLFSCKYKVTVHMLKSKRRSKDESTTFLTPSCATIRSKTH A9JRI8_XENTR A9JRI8_XENTR TKGPEKA--VTQDHHIVLPALLFSCKYKVTVHPARPKDHLKAESIFFTTPPCSTLKGKTH B2RPF8_HUMAN B2RPF8_HUMAN TTGSEASSGMTHENYIILQDLSFSCKYKVTVQPIRPKSHSKAEAVFFTTPPCSALKGKSH KALM_HUMAN KALM_HUMAN TTGSEASSGMTHENYIILQDLSFSCKYKVTVQPIRPKSHSKAEAVFFTTPPCSALKGKSH KALM_CHICK KALM_CHICK TKGLEKVTELTYENYMILKDLSFSCKYKVTVLPAKSKSRFKAESIFFVTPSCSAFKEKTH KALM_COTJA KALM_COTJA TKGLEKVTELTYENYMILKDLSFSCKYKVTVLPAKSKSRFKAESIFFVTPPCSTFKEKTH Q1MT36_DANRE Q1MT36_DANRE TKDEKTA--TVQGTHYVITGLLFACKYRVAVKPVAEQRSEVTTSVT--TPLCLSLMGRRK Q9IAR3_DANRE Q9IAR3_DANRE TKDEKTA--TVQGTHFVITGLLFACKYRVAVKPVAEQKSEVTTSVT--TPLCLSLMGRRK Q2HXL3_ORYLA Q2HXL3_ORYLA TSKEKMT--TVQGTHHTIKGLHFACKYRVSVALKAVPGSEAVAWVM--TPTCSSISIRG- Q4RJ25_TETNG Q4RJ25_TETNG ------------------------------------------------------------ MATCH CONSENSUS ????????????????????L?F?CKY?V???????????????????TP?C????????

Q4RYA2_TETNG Q4RYA2_TETNG KAITCPGEK-AKSRRKVVAKAANLTVSFEIWDGNVTGLFSWDVSTDPPHQ-PLIGYQVTW Q6P938_DANRE Q6P938_DANRE KPIPCSSVP--VVQPKVLVKAENLTAAFSVYLGNVTGLFSWVVAMPQQPQ-QVTGYQVTW Q9IAR4_DANRE Q9IAR4_DANRE KPIPCSSVP--VVQPKVLVKAENLTAAFSVYLGNVTGLFSWVVAMPQQPQ-QVTGYQVTW Q2HXL4_ORYLA Q2HXL4_ORYLA KHIPCPGEG-AAGHPKVLAKPENLTASFSIKDGNITGSFLWGMSRVAPHH-RITGFQVTW Q4S0E8_TETNG Q4S0E8_TETNG KHIPCPGEG---GLPKVLAKPENLTASFSTNESNITGSFLWRVSRVAPHQ-RITGFQVTW A9JRI8_XENTR A9JRI8_XENTR KQINCPSDT-APVVSKVLAKPENLSATFNVQEANITGYFSWQLSKVNLHQ-PMTGFQVTW B2RPF8_HUMAN B2RPF8_HUMAN KPIGCLGEA-GHVLSKVLAKPENLSASFIVQDVNITGHFSWKMAKANLYQ-PMTGFQVTW KALM_HUMAN KALM_HUMAN KPVGCLGEA-GHVLSKVLAKPENLSASFIVQDVNITGHFSWKMAKANLYQ-PMTGFQVTW KALM_CHICK KALM_CHICK KHINCAAEE-VPVLPKVLAKPENLSASFIVQEGNITGHFSWKISKAVLHQ-PMTGFQVTW KALM_COTJA KALM_COTJA KHINCAAEE-VPVLPKVLAKPENLSASFIVQEGNITGHFSWKISKAVLHQ-PMTGFQVTW Q1MT36_DANRE Q1MT36_DANRE KPAACAREERHPQLKKALRRPEKLAVLFQPVNGSLQALFSWQLSPESSGQTPSSGFQFSW Q9IAR3_DANRE Q9IAR3_DANRE KPAACAREERHPQLKKALRRPEKLAVLFQPVNGSLQALFSWQLSPESSGQTASSGFQFSW Q2HXL3_ORYLA Q2HXL3_ORYLA KALACNTKERLPAGRKVVLRPEQLTADFYQLNGTLLSTFRWRMSQHALDPGAVEGFQFTW Q4RJ25_TETNG Q4RJ25_TETNG -----------------------LSADFEQFNGTLLMTVRWRMSQQQLEPSAVEGFQFTW MATCH *:. * .: . * :: *:*.:* CONSENSUS K???C??????????K?????E?L???F??????????F?W?????????????G?Q?TW

Q4RYA2_TETNG Q4RYA2_TETNG LELVPNNLHSNKMPQSLISQSQVLPPERNILVLSDMHPGSLYRLEVQAITEDGD-GPTTS Q6P938_DANRE Q6P938_DANRE AEVITES-RRNNLPNSLISQSQILPPERNILVVSGLQLASLYRLEVQVITAAGQ-GPATS Q9IAR4_DANRE Q9IAR4_DANRE AEVITES-RRNNLPNSLISQSQILPPERNILVVSGLQLASLYRLEVQVITAAGQ-GPATS Q2HXL4_ORYLA Q2HXL4_ORYLA AEINTES-RQNSLPNSIISQSQILPPDHNMLVVSNLRPSTFYRLEVQVITTGGE-GPATV Q4S0E8_TETNG Q4S0E8_TETNG AEITTES-RQNSLPNSIISQSQILPPDHNMLVVSNLRPSTYYRLEVQVITTGGE-GPATV A9JRI8_XENTR A9JRI8_XENTR AEVTTES-RQNSLPNSIISQSQILPADHYMLTVHNLRPSMLYKLEVQVLTTGGE-GPATI B2RPF8_HUMAN B2RPF8_HUMAN AEVTTES-RQNSLPNSIISQSQILPSDHYVLTVPNLRPSTLYRLEVQVLTPGGE-GPATI KALM_HUMAN KALM_HUMAN AEVTTES-RQNSLPNSIISQSQILPSDHYVLTVPNLRPSTLYRLEVQVLTPGGE-GPATI KALM_CHICK KALM_CHICK AEVTTES-RQNSLPNSIISQSQILPADHYVLTVPNLRPSMLYRLEVQVLTTGGE-GPATI KALM_COTJA KALM_COTJA AEVTTES-RQNSLPNSIISQSQILPADHYVLTVPNLRPSMLYRLEVQVLTTGGE-GPATI Q1MT36_DANRE Q1MT36_DANRE VKVSSGS-----SNGSLISQTHILPPDQLSLTVDALQPSSVYRVQVQVLSEAGN-GPSVA Q9IAR3_DANRE Q9IAR3_DANRE VKVSSGS-----SNGSLISQTHILPPDQLSLTVDALQPSSVYRVQVQVLSEAGN-GPSVA Q2HXL3_ORYLA Q2HXL3_ORYLA TLQSELKSDVDRPEHALISQTQTIASTQRSVTVRGLQAGSVYQLQLQVLTAGGRKGAAVS Q4RJ25_TETNG Q4RJ25_TETNG TLLSGVTATKEGIDDTLISQTQTVAATQRSVSVLGLRADSAYQLQLQVLTAGGSSGAAVS MATCH . ::***:: :.. : : : :: *::::*.:: * *.:. CONSENSUS ???????????????S?ISQ?Q?LP?????L?V??L?????Y?L?VQV?T??G??GP???

Q4RYA2_TETNG Q4RYA2_TETNG RTFQTPSHQSIPKHSENRIHIKI------------- Q6P938_DANRE Q6P938_DANRE RTFQTPTH--SKPVLHYKPRIKK---HHLRSVIERH Q9IAR4_DANRE Q9IAR4_DANRE RTFQTPTH--SKPVLHYKPRIKK---HHLRSVIERH Q2HXL4_ORYLA Q2HXL4_ORYLA KTFQTP-N--ILPVTQHRPRLRQHHPHHQKPSVERH Q4S0E8_TETNG Q4S0E8_TETNG KTFQTP-D--ILPVTQHR------------------ A9JRI8_XENTR A9JRI8_XENTR KSFRTP-D--VLPPLPHRPHLKQHRPNHFKPSPEKY B2RPF8_HUMAN B2RPF8_HUMAN KTFRTP-E--LPPSSAHRSHLKHRHPHHYKPSPERY KALM_HUMAN KALM_HUMAN KTFRTP-E--LPPSSAHRSHLKHRHPHHYKPSPERY KALM_CHICK KALM_CHICK KLFRTP-D--LPPFLPHRPHLKQHHPHHYKPPPEKY KALM_COTJA KALM_COTJA KLFRTP-D--LPPFLPHRPHLKH-HPHRYKPPPEKY Q1MT36_DANRE Q1MT36_DANRE KTLHTP----ALNSTIH------------------- Q9IAR3_DANRE Q9IAR3_DANRE KTLHTP----ALNSTIH------------------- Q2HXL3_ORYLA Q2HXL3_ORYLA KTIHTP----TINTSLL------------------- Q4RJ25_TETNG Q4RJ25_TETNG KTIHTP----AFNATL-------------------- MATCH : ::** CONSENSUS ????TP??????????????????????????????


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