Alignment of the gene Family HBG006348 of HOVERGEN

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Threshold: 50% 80% 100%
Size: Bigger Smaller Normal
Isoforms are ON
P70003_XENLA P70003_XENLA -MITLCPVLLSLLLLPTIATSQGQ-----CQIPAPSLTLDTNIRYQFPSFTASRPIQNLV P79950_XENLA P79950_XENLA -MITLCPVLLSLLLLPTIATSQGQ-----CQIPAPSLTLDTNIRYQFPSFTASRPIQNLV Q4SR43_TETNG Q4SR43_TETNG ---------------------------------------NFSVVYTMPFFQARGPIQNIV Q9W650_XENLA Q9W650_XENLA ---MLVAVPVALLFLSLLPQCMGQ-----CEEAAKMAEMDLNLKLNLQNFTTDTPIQSII A0M8T9_CHICK A0M8T9_CHICK KPVTAYPSGIILFLFALLQRSHGQ-----CKEAAKKSEMNLNVKYDLPNFITETPIQNVV Q90975_CHICK Q90975_CHICK KPVTAYPSGIILFLFALLQRSHGQ-----CKEAAKKSEMNLNVKYDLPNFITETPIQNVV MET_ORNAN MET_ORNAN KPPTVHIPGIVVLLFTLVQRSSEE-----CREALRRSGTDVNVSYSLPHFIANTTLLNIV A4FUV6_MOUSE A4FUV6_MOUSE KAPTVLVPGILVLLLSLVQRSHGE-----CKEALVKSEMNVNMKYQLPNFTAETPIQNVV MET_MOUSE MET_MOUSE KAPTVLAPGILVLLLSLVQRSHGE-----CKEALVKSEMNVNMKYQLPNFTAETPIQNVV A4FUV7_MOUSE A4FUV7_MOUSE -APTVLAPGILVLLLSLVQRSHGE-----CKEALVKSEMNVNMKYQLPNFTAETPIQNVV MET_RAT MET_RAT KAPTALAPGILLLLLTLAQRSHGE-----CKEALVKSEMNVNMKYQLPNFTAETPIHNVV Q2IBC7_RAT Q2IBC7_RAT KAPTALAPGILLLLLTLAQRSHGE-----CKEALVKSEMNVNMKYQLPNFTAETPIHNVV MET_RHIFE MET_RHIFE KALAVLGPGLLVHLLTLVQKSGGE-----CKEALVKSAMNVDMKYQLPNFTAETPIQNVV MET_ATEAB MET_ATEAB KASAVLAPGILVILFTLVQKSNCE-----CKEALVKSKMNVNMKYQLPNFTAETPIQNVV MET_ECHTE MET_ECHTE KAPAALAPGILVLLLTLVQKGGGE-----CREALAKSEMNVNMRYRLPNFTADTPIQNVV Q2QLD2_CARPS Q2QLD2_CARPS ------------------------------------------------------------ Q07E11_CAVPO Q07E11_CAVPO KAPTALAPGVLVLLFTLVQRSDGE-----CAEALVKSEMNMNMQYQLPNFTAETPIQHVA MET_DASNO MET_DASNO KAPTVLAPGILVLLFTLVQKSNGE-----CREALAKSEMNVNMKYQLPNFTAETPIQNVV MET_CANFA MET_CANFA KAPAVLAPGILVLLFTLVQKSYGE-----CKEALVKSEMNVNMKYQLPNFTAETPIQNVV MET_MUSPF MET_MUSPF RAPAVLAPGILVLLFTLVQRSCGE-----CKEALVKSEMNVNMKYQLPNFTAETPIQNVV MET_FELCA MET_FELCA KAPAVLAPGILVLLFTLVQKSYGE-----CREALVKSEMNVNMKYQLPNFTAETPIQNVV MET_NEONE MET_NEONE KAPAVLAPGILVLLFTLVQKSYGE-----CREALVKSEMNVNMKYQLPNFTAETPIQNVV MET_MUNMU MET_MUNMU KSPAVLAPGILVFLFTFVQKSDGE-----CKEALVKSRMNVNMQYQLPNFTAETSIQNVV MET_SHEEP MET_SHEEP KAPAVLAPGILVLLFTFVQKSNGE-----CKEALVKSRMNVNMQYQLPNFTAETSIRNVV MET_BOVIN MET_BOVIN KAPAVLAPGILVLLFTFVQKSNGE-----CKEALVKSRMNVNMQYQLPNFTAETSIQNVV A4D7S8_MACEU A4D7S8_MACEU ------------------------------------------------------------ MET_LOXAF MET_LOXAF KAPAVLAPGVLVLLFTLVRKSHGE-----CEEALAKSKMNVNMKYQLPNFTADTPIQNVV MET_RABIT MET_RABIT KAPAVLAPGILVLLFTLVPRSHGE-----CKEALVKSEMNVNMKYQLPNFTAETPIQNVL MET_PIG MET_PIG KAPAVLAPGILVLLFTLVQKSKGE-----CKEALVKSTMNLNMQYQLPNFTAETPIQNVV MET_EULMM MET_EULMM KASAVLAPGILALLFTLVQGNDGE-----CQEALAKSEMNVNMKYQLPNFTAETPIQNVV MET_MICMU MET_MICMU KASAVLAPGILALLFTLVQGSDGE-----CHEALAKSEMNVNMKYQLPNFTAETPIQNVV MET_OTOGA MET_OTOGA KASTVLAPGILALLFTLVQRSNGE-----CKEALAMSKMNVDMKYQLPNFTAETPIQNIV MET_HORSE MET_HORSE KAPAVLAPGILVLLFTLVQKSDGE-----CKEALVKSEMNVNMKYQLPNFTAETPIQNVV MET_CERAE MET_CERAE KAPAVLAPGILMLLFTLVQRSNGE-----CKEALAKSEMNVNMKYQLPNFTAETPIQNVI MET_PAPAN MET_PAPAN KAPAVLVPGILVLLFTLVQRSNGE-----CKEALAKSEMNVNMKYQLPNFTAETAIQNVI MET_COLGU MET_COLGU KAPAVLAPGILVLLFTLVQRSNGE-----CKEALAKSEMNVNMKYQLPNFTAETPIQNVI MET_HYLLE MET_HYLLE KTPAVLAPGILVLLFTLVQRSNGE-----CKEALAKSKMNVNMKYQLPNFTAETPIQNVI MET_GORGO MET_GORGO KAPAVLAPGILVLLFTLVQRSNGE-----CKEALAKSEMNVNMKYQLPNFTAETPIQNVI MET_PANTR MET_PANTR KAPAVLAPGILVLLFTLVQRSNGE-----CKEALAKSEMNVNMKYQLPNFTAETPIQNVI MET_PONAB MET_PONAB KAPAVLAPGILVLLFTLVQRSNGE-----CKEALAKSEMNVNMKYQLPNFTAETLIQNVI B4DLF5_HUMAN B4DLF5_HUMAN ------------------------------------------------------------ A1L467_HUMAN A1L467_HUMAN KAPAVLAPGILVLLFTLVQRSNGE-----CKEALAKSEMNVNMKYQLPNFTAETPIQNVI MET_HUMAN MET_HUMAN KAPAVLAPGILVLLFTLVQRSNGE-----CKEALAKSEMNVNMKYQLPNFTAETPIQNVI Q59EB3_HUMAN Q59EB3_HUMAN ------------------------------------------------------------ MET_CALJA MET_CALJA KAPAVLAPGILVLLFTLVQRSNGE-----CKEALTKSEMNVNMKYQLPNFTAETPIQNVI MET_CALMO MET_CALMO KAPAVLAPGILVLLFTLVQRSNGE-----CKEALTKSEMNVNMKYQLPNFTAETPIQNVV MET_SAIBB MET_SAIBB KAPAVLTPGILLLLFTLVQKSNGE-----CKEALTKSEMNVNMKYQLPNFTAETPIQNVI MET_AOTNA MET_AOTNA KAPAVLAPGILLLLFTLVQRSNGE-----CKEALTKSEMNVNMKYQLPNFTAETPIQNVI MET_ATEGE MET_ATEGE KAPTVLTPGILVLLFILVQRSNGE-----CKEALTKSEMNVNMKYQLPNFTAETPIQNVV Q4RS82_TETNG Q4RS82_TETNG ------------------------------------------------------------ Q64GK4_DANRE Q64GK4_DANRE TIHYSEAASILIILQSLWWGLNCQ-----CEEPIESSKLDLSVTYDLPYFVSDTPIQKLL Q08757_CHICK Q08757_CHICK MGPRCLVCLLLLLAPSLLQAGAWQ-----CRRIPFSSTRNFSVPYTLPSLDAGSPVQNIA B2RUR6_MOUSE B2RUR6_MOUSE GLPLPLLQSSLLLMLLLRLSAASTNLNWQCPRIPYAASRDFSVKYVVPSFSAGGRVQATA RON_MOUSE RON_MOUSE GLPLPLLQSSLLLMLLLRLSAASTNLNWQCPRIPYAASRDFSVKYVVPSFSAGGRVQATA Q6DTW4_CANFA Q6DTW4_CANFA ------------------------------------------------------------ RON_HUMAN RON_HUMAN ELLPPLPQSFLLLLLLPAKPAAGE--DWQCPRTPYAASRDFDVKYVVPSFSAGGLVQAMV MATCH CONSENSUS ?????????????L???????????????C??????????????Y??P?F?A???IQ???

P70003_XENLA P70003_XENLA SQE-----DLLFLTTTNHLYVLTGNELHMLQNLTTGPTN------SQCTLCSKCQ-MGNA P79950_XENLA P79950_XENLA SQE-----DLLFLTTTNHLYVLTGNELHMLQNLTTGPT--NSQCTL-CSKCQMG--NA-- Q4SR43_TETNG Q4SR43_TETNG NNS---FYQEVYVASQNVIEAVDQS-LEKVWELRTGPVGS-----PECKICDLCSIDK-- Q9W650_XENLA Q9W650_XENLA MFK-----GYVYVGAVNKIYVLNEN-LTKISEYKTGPLLKH----SDCLPCKNCTDNLLS A0M8T9_CHICK A0M8T9_CHICK LYK-----HHVYIGAVNKIYVLNET-LQNISVYKTGPILES----PGCAPCEDCKDKANL Q90975_CHICK Q90975_CHICK LYK-----HHVYIGAVNKIYVLNET-LQNISVYKTGPILES----PGCAPCEDCKDKANL MET_ORNAN MET_ORNAN VHR-----DDLYLGAVNKIYVLDKN-LQDFVEYPTGPVLEH----PDCAPCENCSAIAHS A4FUV6_MOUSE A4FUV6_MOUSE LHG-----HHIYLGATNYIYVLNDKDLQKVSEFKTGPVLEH----PDCLPCRDCSSKANS MET_MOUSE MET_MOUSE LHG-----HHIYLGATNYIYVLNDKDLQKVSEFKTGPVLEH----PDCLPCRDCSSKANS A4FUV7_MOUSE A4FUV7_MOUSE LHG-----HHIYLGATNYIYVLNDKDLQKVSEFKTGPVLEH----PDCLPCRDCSSKANS MET_RAT MET_RAT LPG-----HHIYLGATNYIYVLNDKDLQKVSEFKTGPVVEH----PDCFPCQDCSSKANV Q2IBC7_RAT Q2IBC7_RAT LHG-----HHIYLGATNYIYVLDDKDLQKVSEFKTGPVVEH----PDCFPCQDCSSKANV MET_RHIFE MET_RHIFE VHQ-----HYIYLGAVNYIYVLNDTDLQKVAEYRTGPVLEH----PECLPCQDCSHKANA MET_ATEAB MET_ATEAB LHN-----HHIYLGAVNYIYVLSDKTLQKVAEYKTGPVLEH----PDCLPCQDCRHKANL MET_ECHTE MET_ECHTE VHE-----GHVFLGAINSIYVLRERDLQQVSEYKTGPVWEH----PDCLPCQACG----L Q2QLD2_CARPS Q2QLD2_CARPS ------------------------------------------------------------ Q07E11_CAVPO Q07E11_CAVPO LHR-----HHIYLGATNYLYVLNDKDLQKVAEYKTGPVLEH----PDCLPCQDCSSKANL MET_DASNO MET_DASNO LHK-----HHIYLGAVNYIYVLNDKDLQKVAEYKTGPVLEH----PDCVPCQNCSSKANL MET_CANFA MET_CANFA LHK-----HHIYLGAVNYIYVLNDKDLQKVAEYKTGPVLEH----PDCSPCQDCSHKANL MET_MUSPF MET_MUSPF LHK-----HHIYLGAVNYIYVLNDKDLQKVAEYKTGPVLEH----PDCSPCQDCSHKANL MET_FELCA MET_FELCA LHK-----HHIYLGAVNYIYVLNDKDLQKVAEYKTGPVLEH----PDCFPCQDCSHKANL MET_NEONE MET_NEONE LHK-----HHIYLGAVNYIYVLNDKDLQKVAEYKTGPVLEH----PDCFPCQDCSHKANL MET_MUNMU MET_MUNMU LHK-----HHIYLGAVNYIYVLNDKDLQKVAEYKTGPVLEH----PDCFPCQDCSHKANL MET_SHEEP MET_SHEEP LHK-----HHIYLGAINYIYVLNDKDLQKVAEYKTGPVLEH----PDCFPCQDCSHKANL MET_BOVIN MET_BOVIN LHK-----HHIYLGAINYIYVLNDKDLQKVAEYKTGPVLEH----PDCFPCQDCSHKANL A4D7S8_MACEU A4D7S8_MACEU ------------------------------------------------------------ MET_LOXAF MET_LOXAF LHE-----HHIFLGAINNIYVLNDKDLQKVAEYKTGPVLEH----PDCLPCQDCSSKANL MET_RABIT MET_RABIT LHQ-----HHVYLGAINHIYVLNDKDLQKVAEYTTGPVLEH----PDCLPCQDCSSKANS MET_PIG MET_PIG LHK-----HHIYLGALNYIYVLNDIDLRKVAEYKTGPVLEH----PDCFPCQDCSHKANL MET_EULMM MET_EULMM LHE-----HHIYLGATNYIYVLNDKDLQKVSEYKTGPVLEH----PECFPCQNCSNNANL MET_MICMU MET_MICMU LHD-----HHIYLGATNYIYVLNDRDLQKVAEYKTGPVLEH----PDCFPCQNCSDIANF MET_OTOGA MET_OTOGA LHE-----HHIYLGAINYIYVLDDKDLQKVAEYKTGPVLEH----PDCFPCQDCSDKANL MET_HORSE MET_HORSE LHK-----HHIYLGATNYIYVLNDKDLQKVAEYKTGPVLEH----PDCFPCQDCSRKANL MET_CERAE MET_CERAE LHE-----HHIFLGATNYIYVLNEEDLQKVAEYKTGPVLEH----PDCFPCQDCSSKANL MET_PAPAN MET_PAPAN LHE-----HHIFLGATNYIYVLNEEDLQKVAEYKTGPVLEH----PDCFPCQDCSSKANL MET_COLGU MET_COLGU LHE-----HHIFLGATNYIYVLNEEDLQKVAEYKTGPVLEH----PDCFPCQDCSSKANL MET_HYLLE MET_HYLLE LHE-----HHIFLGATNYIYVLNEEDLQKVAEYKTGPVLEH----PDCFPCQDCSSKANL MET_GORGO MET_GORGO LHE-----HHIFLGATNYIYVLNEEDLQKVAEYKTGPVLEH----PDCFPCQDCSSKANL MET_PANTR MET_PANTR LHE-----HHIFLGATNYIYVLNEEDLQKVAEYKTGPVLEH----PDCFPCQDCSSKANL MET_PONAB MET_PONAB LHE-----HHIFLGATNYIYVLNEEDLQKVAEYKTGPVLEH----PDCFPCQDCSSKANL B4DLF5_HUMAN B4DLF5_HUMAN ------------------------------------------------------------ A1L467_HUMAN A1L467_HUMAN LHE-----HHIFLGATNYIYVLNEEDLQKVAEYKTGPVLEH----PDCFPCQDCSSKANL MET_HUMAN MET_HUMAN LHE-----HHIFLGATNYIYVLNEEDLQKVAEYKTGPVLEH----PDCFPCQDCSSKANL Q59EB3_HUMAN Q59EB3_HUMAN ------------------------------------------------------------ MET_CALJA MET_CALJA LHE-----HHIFLGATNYIYVLNEEDLQKVAEYRTGPVLEH----PDCFPCQDCSSKANL MET_CALMO MET_CALMO LHE-----HHIFLGATNYIYVLNEEDLQKVAEHRTGPVLEH----PDCFPCQDCSSKANL MET_SAIBB MET_SAIBB LHE-----HHIFLGATNYIYVLNEEDLQKVAEHRTGPVLEH----PDCFPCQDCSSKANL MET_AOTNA MET_AOTNA LHE-----HHIFLGATNYIYVLNEEDLQKVAEHRTGPVLEH----PDCFPCQDCSSKANL MET_ATEGE MET_ATEGE LHE-----HHIFLGATNYIYVLNEEDLQKVAEHRTGPVLEH----PDCFPCQDCSSKANL Q4RS82_TETNG Q4RS82_TETNG ------------------------------------------------------------ Q64GK4_DANRE Q64GK4_DANRE EIN-----GTVYVGAVNRLYALSKD-LKKKHEYKTGPVHEGPDCKTPTDQCSGCE-NK-- Q08757_CHICK Q08757_CHICK VFP---DPPTVFVAVRNRILVVDPE-LRLRSVLVTGPTGSAP-----CEICRLCPAAV-- B2RUR6_MOUSE B2RUR6_MOUSE AYE-DSTNSAVFVATRNHLHVLGPD-LQFIENLTTGPIGN-----PGCQTCASCG-PG-- RON_MOUSE RON_MOUSE AYE-DSTNSAVFVATRNHLHVLGPD-LQFIENLTTGPIGN-----PGCQTCASCG-PG-- Q6DTW4_CANFA Q6DTW4_CANFA ------------------------------------------------------------ RON_HUMAN RON_HUMAN TYEGDRNESAVFVAIRNRLHVLGPD-LKSVQSLATGPAGD-----PGCQTCAACG-PG-- MATCH CONSENSUS ????????????????N??YVL????L???????TGP????????P?C??C??C??????

P70003_XENLA P70003_XENLA LPSQPEDTESQVLVADPEE--SVIYSCGSSLHGLCFMHVIASSKIVDSK----CLFNQNR P79950_XENLA P79950_XENLA LPSQPEDTESQVLVADPEE--SVIYSCGSSLHGLCFMHVIASSKIVDSK----CLFNQNR Q4SR43_TETNG Q4SR43_TETNG DPNFLEDTNNQVLLLDTMF--MYLYTCGSSQHGVCYFHQLNWTGEPPSLSK--CLYRKES Q9W650_XENLA Q9W650_XENLA PNGTWKDSVNMALFVQDFYD-DQLISCGNIRKGECQRHTLHSDKPWDIASDVHCLYSSQM A0M8T9_CHICK A0M8T9_CHICK SNSVWKDNVNMALLLETYYD-DQLISCGSVSGGVCHRHIIPPDNPADIESEVHCMYSPQV Q90975_CHICK Q90975_CHICK SNSVWKDNVNMALLLETYYD-DQLISCGSVSGGVCHRHIIPPDNPADIESEVHCMYSPQV MET_ORNAN MET_ORNAN SKADLRDNVNMALLIETYYHYEQLIICGSVDGGACWRFPLPLGEPTDFHSKKHCMFSHQA A4FUV6_MOUSE A4FUV6_MOUSE SGGVWKDNINMALLVDTYYD-DQLISCGSVNRGTCQRHVLPPDNSADIQSEVHCMFSPEE MET_MOUSE MET_MOUSE SGGVWKDNINMALLVDTYYD-DQLISCGSVNRGTCQRHVLPPDNSADIQSEVHCMFSPEE A4FUV7_MOUSE A4FUV7_MOUSE SGGVWKDNINMALLVDTYYD-DQLISCGSVNRGTCQRHVLPPDNSADIQSEVHCMFSPEE MET_RAT MET_RAT SGGVWKDNVNMALLVDTYYD-DQLISCGSVNRGTCQRHVLPPDNAADIQSEVHCMFSPLA Q2IBC7_RAT Q2IBC7_RAT SGGVWKDNVNMALLVDTYYD-DQLISCGSVNRGTCQRHVLPPDNAADIQSEVHCMFSPLA MET_RHIFE MET_RHIFE SGGVWADNVNMALLVDTYYD-DQLISCGSVRRGTCRRHVLRSD-AADIRSEVHCMFSPQA MET_ATEAB MET_ATEAB SNGIWKDNINMALLVDTYYD-DQLISCGSVHRGTCQRHVLPPNNAADIQSEVHCMYTPQP MET_ECHTE MET_ECHTE AGGQWRENVNMALLVETYYD-DQLISCGSVHRGTCQRHVLPRDNPADIQAEVHCMHSPRA Q2QLD2_CARPS Q2QLD2_CARPS ------------------------------------------------------------ Q07E11_CAVPO Q07E11_CAVPO SGAIWKDNINMAMLIDTYYD-DQLISCGSVNRGTCQRHVLPLSNTADIQAKVYCMFSQAD MET_DASNO MET_DASNO SGSAWRDNINMALLVDTYYD-DQLISCGSVNRGTCQRHVFPPHNTADIQSEVRCMYSPQP MET_CANFA MET_CANFA SGGVWEDNINMALLVDTYYD-DQLISCGSVHRGTCQRHILPPSNIADIQSEVHCMYSSQA MET_MUSPF MET_MUSPF SGAVWKDNINMALLIDIYYD-DQLISCGSVQRGTCQRHVLPRSNTADIQSEVHCMYSPQA MET_FELCA MET_FELCA SGGVWKDNINMALLIDTYYD-DQLISCGSVHRGTCQRHVLPPSNTADILSKVHCMYSPQA MET_NEONE MET_NEONE SGGVWKDNINMALLIDTYYD-DQLISCGSVHRGTCQRHVLPPSNTADILSKVHCMYSPQA MET_MUNMU MET_MUNMU SGGVWKDNINMALLVDTYYD-DQLISCGSVHRGTCQRHVLPPNNTADIESEVHCMYSPQA MET_SHEEP MET_SHEEP SGGVWKDNINMALLVDTYYD-DQLISCGSVHRGTCQRHVLPPNNTADIESEVHCMYSPQE MET_BOVIN MET_BOVIN SGGVWKDNINMALLVDTYYD-DQLISCGSVHRGTCQRHVLPPNNTADIESEVHCMYSPQA A4D7S8_MACEU A4D7S8_MACEU ------------------------------------------------------------ MET_LOXAF MET_LOXAF SGSVWKDNINMALLVDTYYD-DQLITCGSVNRGTCQRHVLPPDNPADIHSKVHCMYSPQA MET_RABIT MET_RABIT SGAVWKDNINLALLVDKYYD-DQLISCGSVNRGTCQRHVLPPDNPADIQSGVYCMFSPQA MET_PIG MET_PIG SGGIWRDNINMALLVDTYYD-DQLISCGSVHRGTCQRHVLPPDNIADIKSEVHCMYSPQV MET_EULMM MET_EULMM SSGIWKDNINMALLVDRYYD-DQLISCGSVNRGACQRHILPPDNPADIQSKVHCMFSPQA MET_MICMU MET_MICMU SGGIWKDNINRALLVDTYYD-DQLISCGSVNRGACQRHVLPPDNPADIRSEVHCMFSPQA MET_OTOGA MET_OTOGA SGGIWKDNVNMALLVDTYYD-DQLISCGSVNRGACQRHVLPRNNAADIQSKVHCMFSPQA MET_HORSE MET_HORSE SGGAWKDNINMALLVDTYYD-DQLISCGSVHRGTCQRHVLPLNNVADIQSEVYCMYSPQA MET_CERAE MET_CERAE SGGVWKDNINMALVVDTYYD-DQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQI MET_PAPAN MET_PAPAN SGGVWKDNINMALVVDTYYD-DQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQI MET_COLGU MET_COLGU SGGVWKDNINMALVVDTYYD-DQLISCGSGNRGTCQRHVFPHNHTADIQSEVHCIFSPQI MET_HYLLE MET_HYLLE SGGVWKDNINMALVVDTYYD-DQLISCGSINRGTCQRHVFPHNHTADIQSEVHCIFSPQI MET_GORGO MET_GORGO SGGIWKDNINMALVVDTYYD-DQLISCGSVNRGTCQRHVFPHNHTVDIQSEVHCIFSPQI MET_PANTR MET_PANTR SGGVWKDNINMALVVDTYYD-DQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQI MET_PONAB MET_PONAB SGGVWKDNINMALVVDTYYD-DQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQI B4DLF5_HUMAN B4DLF5_HUMAN ------------------------------------------------------------ A1L467_HUMAN A1L467_HUMAN SGGVWKDNINMALVVDTYYD-DQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQI MET_HUMAN MET_HUMAN SGGVWKDNINMALVVDTYYD-DQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQI Q59EB3_HUMAN Q59EB3_HUMAN ------------------------------------------------------------ MET_CALJA MET_CALJA SGGVWKDNINMALVVDTYYD-DQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSAQT MET_CALMO MET_CALMO SGGVWKDNINMALVVDTYYD-DQLISCGSVNRGTCQRHVFPHNHTADIQSDVHCIFSPQI MET_SAIBB MET_SAIBB SGGVWKDNINMALVVDTYYD-DQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQT MET_AOTNA MET_AOTNA SGGVWKDNINMALVVDTYYD-DQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQT MET_ATEGE MET_ATEGE SGGVWKDNINMALVVDTYYD-DQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQT Q4RS82_TETNG Q4RS82_TETNG ------------------------------------------------------------ Q64GK4_DANRE Q64GK4_DANRE PRNI--NNTNMALLMETFYD-LELFSCGSVGNGVCSRHVLE---DGPLGAEVTCMYTKKN Q08757_CHICK Q08757_CHICK DAPGPEDVDNVLLLLDPVE--PWLYSCGTARRGLCYLHQLDVRGSEVTIASTRCLYSAAA B2RUR6_MOUSE B2RUR6_MOUSE PHGPPKDTDTLVLVMEPGL--PALVSCGSTLQGRCFLHELEPRGKALHLAAPACLFSANN RON_MOUSE RON_MOUSE PHGPPKDTDTLVLVMEPGL--PALVSCGSTLQGRCFLHELEPRGKALHLAAPACLFSANN Q6DTW4_CANFA Q6DTW4_CANFA ------------------------------------------------------------ RON_HUMAN RON_HUMAN PHGPPGDTDTKVLVLDPAL--PALVSCGSSLQGRCFLHDLEPQGTAVHLAAPACLFSAHH MATCH CONSENSUS ??????D??N??L??????????L?SCGS???G?C??H???????????????C??S???

P70003_XENLA P70003_XENLA N--NASSCPDCIASPLGTLLTVVTQSRVVYFYTASSLDSPIAKSYSPTSISIRRLLGSED P79950_XENLA P79950_XENLA N--NASSCPDCIASPLGTLLTVVTQSRVVYFYTASSLDSPIAKSYSPTSISIRRLLGSED Q4SR43_TETNG Q4SR43_TETNG N--SAAYCPDCVASSLGTKVTMVEEGQTVYFFVASTVNDSVSQRYGRKSLSVRRPLATED Q9W650_XENLA Q9W650_XENLA VE-DKDSCPDCIVSTAGSKILVTVGDRFVKFFVGSTLTGQ---PSTIHSVSVRRLKETQD A0M8T9_CHICK A0M8T9_CHICK DG-EADNCPDCVVSTLGTKVLVTEKDRFVNFFVGNTVTSAFQPPHVLHSISVRRLKETQD Q90975_CHICK Q90975_CHICK DG-EADNCPDCVVSTLGTKVLVTEKDRFVNFFVGNTMTSAFQPPHVLHSISVRRLKETQD MET_ORNAN MET_ORNAN DE-ESKDCPDCIVSTLGTKVLLVEKDRFVNFFVGNTINSSSHPFSSLHSISVRRLKETLD A4FUV6_MOUSE A4FUV6_MOUSE ---ESGQCPDCVVSALGAKVLLSEKDRFINFFVGNTINSSYPPGYSLHSISVRRLKETQD MET_MOUSE MET_MOUSE ---ESGQCPDCVVSALGAKVLLSEKDRFINFFVGNTINSSYPPGYSLHSISVRRLKETQD A4FUV7_MOUSE A4FUV7_MOUSE ---ESGQCPDCVVSALGAKVLLSEKDRFINFFVGNTINSSYPPGYSLHSISVRRLKETQD MET_RAT MET_RAT EE-ESGQCPDCVVSALGAKVLLSEKDRFINFFVGNTINSSYPPDYSLHSISVRRLKETQD Q2IBC7_RAT Q2IBC7_RAT EE-ESGQCPDCVVSALGAKVLLSEKDRFINFFVGNTINSSYPPDYSLHSISVRRLKETQD MET_RHIFE MET_RHIFE DE-EPGRCPDCVVSALGTKVLLSEKDRFINFFVGNTISSAHLPGRALHSISVRRLKETQD MET_ATEAB MET_ATEAB EE-EPSQCPDCVVSALGTKVLLSEKNRFINFFVGNTINSSYLPDHSLHSMSVRRLKETQD MET_ECHTE MET_ECHTE DEDEASQCPDCVVSALGTKVLLAEKQRFVNFFVGNTLNGSSLPGHALHSISVRRIKETQD Q2QLD2_CARPS Q2QLD2_CARPS ------------------------------------------------------------ Q07E11_CAVPO Q07E11_CAVPO E--ESGQCPDCVVSALGTKVLLSEKSRFINFFVGNTINSSYLPDHSLHSISVRRLKETLD MET_DASNO MET_DASNO EE-EPSQCPDCVVSALGTKVLLTVKDRFINFFVGNTINSSYLPDHSLHSISVRRLKETQD MET_CANFA MET_CANFA DE-EPSQCPDCVVSALGTKVLISEKDRFINFFVGNTINSSDHPDHSLHSISVRRLKETQD MET_MUSPF MET_MUSPF DE-EPGQCPDCVVSALGTKVLISEKTRFINFFVGNTINSSSHPDHSLHSISVRRLKETQD MET_FELCA MET_FELCA DE-ESSHCPDCVVSALGTKVLISEKGRFINFFVGNTINSSYLTDHSLHSISVRRLKETQD MET_NEONE MET_NEONE DE-ESSHCPDCVVSALGTKVLISEKGRFINFFVGNTINSSYLTDHSLHSISVRRLKETQD MET_MUNMU MET_MUNMU DE-ETSQCPDCVVSALGTKVLLSEKERFINFFVGNTINSSYLPDHSLHSISVRRLKETQD MET_SHEEP MET_SHEEP DE-ETNQCPDCVVSALGTKVLLSEKERFINFFVGNTINSSYFPDHSLHSISVRRLKETQD MET_BOVIN MET_BOVIN DE-ETNQCPDCVVSALGTKVLLSEKDRFINFFVGNTINSSYLPDYILHSISVRRLKETQD A4D7S8_MACEU A4D7S8_MACEU ------------------------------------------------------------ MET_LOXAF MET_LOXAF DE-EPSKCPDCVVSALGTKVLLTEKDRFINFFVGNTVNSSYLPDHSLHSISVRRLKETQD MET_RABIT MET_RABIT DE-EPGQCPDCVVSPLGAKVLLSKKQRFIYFFVGNTINSSYLPDHSLHSISVRRLKETQD MET_PIG MET_PIG DE-EPSQCPDCVVSALGTKVLLSEKDRFINFFVGNTINSSYLPDHSLHSISVRRLKETQD MET_EULMM MET_EULMM DE-EPSQCPDCVVSALGAKVLLSEKDRFINFFVGNTINSSYFPDHPLHSISVRRLKETQD MET_MICMU MET_MICMU DE-EPGQCPDCVVSALGAKVLLSVKDRFINFFVGNTLNSSYFPDHPLHSISVRRLKETQD MET_OTOGA MET_OTOGA DE-EPGQCPDCVVSALGAKVLLSEKDRFINFFVGNTINSSYFPNHPLHSISVRRLKETQD MET_HORSE MET_HORSE E--EPHQCPDCVVSALGTKVLLSEKDRFVTFFVGNTINSSYLPDHSLHSISVRRLKETQD MET_CERAE MET_CERAE E--EPSQCPDCVVSALGAKVLSSVKDRFINFFVGNTINSSYFPHHPLHSISVRRLKETKD MET_PAPAN MET_PAPAN E--EPSQCPDCVVSALGAKVLSSVKDRFINFFVGNTINSSYFPHHPLHSISVRRLKETKD MET_COLGU MET_COLGU E--EPSQCPDCVVSALGAKVLSSVKDRFINFFVGNTINSSYFPHHPLHSISVRRLKETKD MET_HYLLE MET_HYLLE E--EPSQCPDCVVSALGAKVLSSVKDRFINFFVGNTINSSYFPDHPLHSISVRRLKETKD MET_GORGO MET_GORGO E--EPSQCPDCVVSALGAKVLSSVKDRFINFFVGNTINSSYFPDHPLHSISVRRLKETKD MET_PANTR MET_PANTR E--EPSQCPDCVVSALGAKVLSSVKDRFINFFVGNTINSSYFPDHPLHSISVRRLKETKD MET_PONAB MET_PONAB E--EPSQCPDCVVSALGAKVLSSVKDRFINFFVGNTINSSYFPDHPLHSISVRRLKETKD B4DLF5_HUMAN B4DLF5_HUMAN ------------------------------------------------------------ A1L467_HUMAN A1L467_HUMAN E--EPSQCPDCVVSALGAKVLSSVKDRFINFFVGNTINSSYFPDHPLHSISVRRLKETKD MET_HUMAN MET_HUMAN E--EPSQCPDCVVSALGAKVLSSVKDRFINFFVGNTINSSYFPDHPLHSISVRRLKETKD Q59EB3_HUMAN Q59EB3_HUMAN ------------------------------------------------------------ MET_CALJA MET_CALJA E--EPSQCPDCMVSALGTKVLLSVKDRFLNFFVGNTINSSYFPDHSLHSISVRRLKETKD MET_CALMO MET_CALMO E--EPSQCPDCVVSALGTKVLLSVKDRFLNFFVGNTVNSSYFPDHSLHSISVRRLKETKN MET_SAIBB MET_SAIBB E--EPSQCPDCVVSALGTKVLLSVKERFLNFFVGNTINSSYVPDHSLHSISVRRLKETKD MET_AOTNA MET_AOTNA E--EPSQCPDCVVSALGTKVLLSVKHRFLNFFVGNTINSSYFPDHSLHSISVRRLKETKD MET_ATEGE MET_ATEGE E--EPSQCPDCVVSALGTKVLLSVKDRFLNFFVGNTINSSYFPDHSLHSISVRRLKETKD Q4RS82_TETNG Q4RS82_TETNG ------------------------------------------------------------ Q64GK4_DANRE Q64GK4_DANRE EG-SSHGCPDCLAGPAGTQILNIMSGRVVRFFVANSEPLESNGPRLHHTISIRKMRETQD Q08757_CHICK Q08757_CHICK N--SPVNCPDCVASPLGSTATVVADRYTASFYLGSTVNSSVAARYSPRSVSVRRLKGTRD B2RUR6_MOUSE B2RUR6_MOUSE N--KPEACTDCVASPLGTRVTVVEQGHASYFYVASSLDPELAASFSPRSVSIRRLKSDTS RON_MOUSE RON_MOUSE N--KPEACTDCVASPLGTRVTVVEQGHASYFYVASSLDPELAASFSPRSVSIRRLKSDTS Q6DTW4_CANFA Q6DTW4_CANFA ------------------------------------------------------------ RON_HUMAN RON_HUMAN N--RPDDCPDCVASPLGTRVTVVEQGQASYFYVASSLDAAVAGSFSPRSVSIRRLKADAS MATCH CONSENSUS ???????CPDC??S?LG??V??????R???F?V???????????????S?S?RRLK?T?D

P70003_XENLA P70003_XENLA GFG--GGFHSLTVLETFRDSYPIHYVHTFTSGSYVYFLTVQPEHP--LSSTYHSRVVRLY P79950_XENLA P79950_XENLA GFG--GGFHSLTVLETFRDSYPIHYVHTFTSGSYVYFLTVQPEHP--LSSTYHSRVVRLY Q4SR43_TETNG Q4SR43_TETNG GFY--SDVRGLTVLPSLRNAYHIEYVYSFFTQEFVFFLSVQRESPDQESSPFQTRLGRLP Q9W650_XENLA Q9W650_XENLA GFEYLTDQSYIDVLPHLRDIYPIRYIYTFESNNFVYFLTVQRESL--DSQAYHTRIVRIC A0M8T9_CHICK A0M8T9_CHICK GFEFLTDQSYIDILPQFRDSYPIKYVHAFEHDHFVYFLTVQRESL--DSQTFHTRIIRFC Q90975_CHICK Q90975_CHICK GFEFLTDQSYIDILPQFRDSYPIKYVHAFEHDHFVYFLTVQRESL--DSQTFHTRIIRFC MET_ORNAN MET_ORNAN GFKFLTDQSYIDVLPQFRDSYPIKYIHAFESNQFIYFLTVQKETV--ESQTFHTRIIRFC A4FUV6_MOUSE A4FUV6_MOUSE GFKFLTDQSYIDVLPEFQDSYPIKYIHAFESNHFIYFLTVQKETL--DAQTFHTRIIRFC MET_MOUSE MET_MOUSE GFKFLTDQSYIDVLPEFLDSYPIKYIHAFESNHFIYFLTVQKETL--DAQTFHTRIIRFC A4FUV7_MOUSE A4FUV7_MOUSE GFKFLTDQSYIDVLPEFQDSYPIKYIHAFESNHFIYFLTVQKETL--DAQTFHTRIIRFC MET_RAT MET_RAT GFKFLTDQSYIDVLPEFRDSYPIKYIHAFESNHFIYFLTVQKETL--DAQTFHTRIIRFC Q2IBC7_RAT Q2IBC7_RAT GFKFLTDQSYIDVLPEFRDSYPIKYIHAFESNHFIYFLTVQKETL--DAQTFHTRIIRFC MET_RHIFE MET_RHIFE GFKFLTDQSYIDVLPEFRDSYPIKYVHAFESNHFIYFLTVQRETL--DAQTFHTRIVRFC MET_ATEAB MET_ATEAB GFKFLTDQSYIDVLPEFRDSYPIKYIHAFKSNHFIYFLTVQRETL--DAQTFHTRIIRFC MET_ECHTE MET_ECHTE GFKFLTDKSYIDVLPEFQASYPIKYIHAFESNRFIYFLTVQRETL--DSPSFHTRIIRFC Q2QLD2_CARPS Q2QLD2_CARPS ------------------------------------------------------------ Q07E11_CAVPO Q07E11_CAVPO GFKFLTDQSYIDVLPEFRDSYPIKYVHAFESSHFIYFLTVQKETL--DAQTFHTRIIRFC MET_DASNO MET_DASNO GFKFLTDQSYIDVLPEFRDSYPIKYVHAFESNHFIYFLTVQRETL--DSQTFHTRIIRFC MET_CANFA MET_CANFA GFKFLTDQSYIDVLPEFRDSYPIKYVHAFESNHFIYFLTVQRETL--DAQTFHTRIIRFC MET_MUSPF MET_MUSPF GFKFLTDQSYIDVLPEFRDSYPIKYVHAFESNHFIYFLTVQRETL--DAQTFHTRVIRFC MET_FELCA MET_FELCA GFKFLTDQSYIDVLPEFRDSYPIKYIHAFESNRFIYFLTVQRETL--DAQTFHTRIIRFC MET_NEONE MET_NEONE GFKFLTDQSYIDVLPEFRDSYPIKYIHAFESNRFIYFLTVQRETL--DAQTFHTRIIRFC MET_MUNMU MET_MUNMU GFKFLTDQSYIDVLPELQDSYPIKYVHAFESNHFIYFLTVQRETL--DAQTFHTRIIRFC MET_SHEEP MET_SHEEP GFKFLTDQSYIDVLPELQDSYPIKYVHAFESNHFIYFLTVQRETL--DAQTFHTRIIRFC MET_BOVIN MET_BOVIN GFKFLTDQSYIDVLPELRDSYPIKYVHAFESNHFIYFLTVQRETL--DAQTFHTRIIRFC A4D7S8_MACEU A4D7S8_MACEU ------------------------------------------------------------ MET_LOXAF MET_LOXAF GFKFLTDQSYIDVLPEFRDSYPIKYVHAFKHNQFIYFLTVQRETL--ESQTFHTRIIRFC MET_RABIT MET_RABIT GFKFLTDQSYIDVLPEFRDSYPIKYVHAFESNHFIYFLTVQKETL--DAQTFHTRIIRFC MET_PIG MET_PIG GFKFLTDQSYIDVLPEFRDSYPIKYVHAFESNHFIYFLTVQRETL--DAQTFHTRIIRFC MET_EULMM MET_EULMM GFKFLTDQSYIDVLPEFRDSYPIKYVHAFESNHFIYFLTVQKETL--DAQTFHTRIIRFC MET_MICMU MET_MICMU GFKFLTDQSYIDVLPEFRDSYPIKYVHAFESNHFIYFLTVQRETL--DAQTFHTRIIRFC MET_OTOGA MET_OTOGA GFKFLTDQSYIDVLPEFRDSYPIKYVHAFESNHFIYFLTVQRETL--DSQTFHTRIIRFC MET_HORSE MET_HORSE GFKFLTDQSYIDVLPEFRDSYPIKYIHAFESNHFIYFLTVQRETL--DAQTFHTRIIRFC MET_CERAE MET_CERAE GFMFLTDQSYIDVLPEFRDSYPIKYVHAFESNNFIYFLTVQRETL--NAQTFHTRIIRFC MET_PAPAN MET_PAPAN GFMFLTDQSYIDVLPEFRDSYPIKYIHAFESNNFIYFLTVQRETL--NAQTFHTRIIRFC MET_COLGU MET_COLGU GFVFLTDQSYIDVLPEFRDSYPIKYVHAFESNNFIYFLSVQRETL--NAQTFHTRIIRFC MET_HYLLE MET_HYLLE GFMFLTDQSYIDVLPEFRDSYPIKYVHAFESNNFIYFLTVQRETL--DAQTFHTRIIRFC MET_GORGO MET_GORGO GFMFLTDQSYIDVLPEFRDSYPIKYVHAFESNNFIYFLTVQRETL--DAQTFHTRIIRFC MET_PANTR MET_PANTR GFMFLTDQSYIDVLPEFRDSYPIKYVHAFESNNFIYFLTVQRETL--DAQTFHTRIIRFC MET_PONAB MET_PONAB GFMFLTDQSYIDVLPEFRDSYPIKYVHAFESNNFIYFLTVQRETL--DAQTFHTRIIRFC B4DLF5_HUMAN B4DLF5_HUMAN ------------------------------------------------------------ A1L467_HUMAN A1L467_HUMAN GFMFLTDQSYIDVLPEFRDSYPIKYVHAFESNNFIYFLTVQRETL--DAQTFHTRIIRFC MET_HUMAN MET_HUMAN GFMFLTDQSYIDVLPEFRDSYPIKYVHAFESNNFIYFLTVQRETL--DAQTFHTRIIRFC Q59EB3_HUMAN Q59EB3_HUMAN ------------------------------------------------------------ MET_CALJA MET_CALJA GFMFLTDQSYVDVLPEFRDSYPIKYVHAFESNNFIYFLTVQRETL--NAQTFHTRIIRFC MET_CALMO MET_CALMO GFMFLTDQSYVDVLPEFRDSYPIKYVHAFESNNFIYFLTVQRETL--NAQTFHTRIIRFC MET_SAIBB MET_SAIBB GFMFLTDQSYVDVLPEFRDSYPIKYVHAFESNNFIYFLAVQRETL--NAQTFHTRIIRFC MET_AOTNA MET_AOTNA GFMFLTDQSYVDVLPEFRDSYPIKYVHAFESNNFIYFLTVQRETL--NAQTFHTRIIRFC MET_ATEGE MET_ATEGE GFMFLTDQSYVDVLPEFRDSYPIKYVHAFESNNFIYFLTVQRETL--NAQTFHTRIIRFC Q4RS82_TETNG Q4RS82_TETNG ------------------------------------------------------------ Q64GK4_DANRE Q64GK4_DANRE GFEFFSEQSYMDLAPSLRGNYPLHYVYSFQSGPYVYFLTVQREGG--NSKAFHTRIVRMC Q08757_CHICK Q08757_CHICK GFA--DPFHSLTVLPHYQDVYPIHYVHSFTDGDHVYLVTVQPEFP--GSSTFHTRLVRLS B2RUR6_MOUSE B2RUR6_MOUSE GFQ--PGFPSLSVLPKYLASYLIKYVYSFHSGDFVYFLTVQPISVTSPPSALHTRLVRLN RON_MOUSE RON_MOUSE GFQ--PGFPSLSVLPKYLASYLIKYVYSFHSGDFVYFLTVQPISVTSPPSALHTRLVRLN Q6DTW4_CANFA Q6DTW4_CANFA ------------------------------------------------------------ RON_HUMAN RON_HUMAN GFA--PGFVALSVLPKHLVSYSIEYVHSFHTGAFVYFLTVQPASVTDDPSALHTRLARLS MATCH CONSENSUS GF??????????VLP????SYPI?Y?H?F????F?YFLTVQ?E?????????HTR??R??

P70003_XENLA P70003_XENLA KKEEEMRSYRELILECRLEPK--RRRRRRRAEPR---IFNVLQAAHVATVGSTLAGELDI P79950_XENLA P79950_XENLA KKEEEMRSYRELILECRLEPK--RRRRRRRAEPR---IFNVLQAAHVATVGSTLAGELDI Q4SR43_TETNG Q4SR43_TETNG RNEWEMKRYREVILECRFEPK--RRRRAVGSEPYKDVVYNVVQAAHFGKAGRELAKELGA Q9W650_XENLA Q9W650_XENLA SSDSELRSYIEMPLECIFTEK--RRKRSTASA-----VFNIVQAAYLGRAGEDLAEEMGV A0M8T9_CHICK A0M8T9_CHICK TLDSEMRSYMEMPLECIFTEK--RRKRSIRKE-----VFNILQAAYVSKPGAALAHEMGL Q90975_CHICK Q90975_CHICK TLDSEMRSYMEMPLECIFTEK--RRKRSIRKE-----VFNILQAAYVSKPGAALAHEMGL MET_ORNAN MET_ORNAN SMDSELHSYMEMPLECILTEK--RRRRSTNKE-----VFNVLQAAYVSKPGAHLARQIGT A4FUV6_MOUSE A4FUV6_MOUSE SVDSGLHSYMEMPLECILTEK--RRKRSTREE-----VFNILQAAYVSKPGANLAKQIGA MET_MOUSE MET_MOUSE SVDSGLHSYMEMPLECILTEK--RRKRSTREE-----VFNILQAAYVSKPGANLAKQIGA A4FUV7_MOUSE A4FUV7_MOUSE SVDSGLHSYMEMPLECILTEK--RRKRSTREE-----VFNILQAAYVSKPGANLAKQIGA MET_RAT MET_RAT SVDSGLHSYMEMPLECILTEK--RRKRSTREE-----VFNILQAAYVSKPGANLAKQIGA Q2IBC7_RAT Q2IBC7_RAT SVDSGLHSYMEMPLECILTEK--RRKRSTREE-----VFNILQAAYVSKPGANLAKQIGA MET_RHIFE MET_RHIFE SVDSGLHSYVEMPLECILTEK--RRRRSARSE-----VFNILQAAYVGKPGTHLANQIGV MET_ATEAB MET_ATEAB SGDSGLHSYMEMPLECILTEK--RRKRAAREE-----VFNILQAAYVSKPGAHLARQIGA MET_ECHTE MET_ECHTE SADSGLRSYMEMPLECILTEK--RRKRALRSE-----VFNVLQAAYVGKPGAQLAKQIGA Q2QLD2_CARPS Q2QLD2_CARPS ------------------------------------------------------------ Q07E11_CAVPO Q07E11_CAVPO SADSGLHSYMEMPLECILTEK--RRKRSTGQE-----VFNILQAAYVGTAGAHLAKQIRV MET_DASNO MET_DASNO SVDSGLHSYMEMPLECILTEK--RRKRSTRQE-----VFNILQAAYVSKPGAHLAKQIGA MET_CANFA MET_CANFA SVDSGLHSYMEMPLECILTEK--RRKRSTREE-----VFNILQAAYVSKPGAHLAKQIGA MET_MUSPF MET_MUSPF SVDSGLHSYMEMPLECILTEK--RRKRSTREE-----VFNILQAAYVGKPGAHLAKQIGA MET_FELCA MET_FELCA SVDSGLHSYMEMPLECILTEK--RRKRSTREE-----VFNILQAAYVSKPGAHLAKQIGA MET_NEONE MET_NEONE SVDSGLHSYMEMPLECILTEK--RRKRSTREE-----VFNILQAAYVSKPGAHLAKQIGA MET_MUNMU MET_MUNMU STDSGLHSYMEMPLECILTEK--RRKRSTKQE-----VFNILQAAYVSKPGAQLARQIGA MET_SHEEP MET_SHEEP SADSGLHSYMEMPLECILTEK--RRKRSTKQE-----VFNILQAAYVSKPGAQLARQIGA MET_BOVIN MET_BOVIN SADSGLHSYMEMPLECILTEK--RRKRSTKQE-----VFNILQAAYVSKPGAQLARQIGA A4D7S8_MACEU A4D7S8_MACEU ------------------------------------------------------------ MET_LOXAF MET_LOXAF SVDSGLHSYMEMPLECILTEK--RRKRSAREE-----VFNILQAAYVSKPGAYLAKQIGA MET_RABIT MET_RABIT SKDSGLHSYMEMPLECILTEK--RRKRATREE-----VFNILQAAYVSKPGAHLARQIGA MET_PIG MET_PIG SVDSGLHSYMEMPLECILTEK--RRKRSTREE-----VFNILQAAYVSKPGTQLAKQIGA MET_EULMM MET_EULMM SVDSGLHSYMEMPLECILTEK--RRKRSTREE-----VFNILQAAYVSKPGAQLAKQIGA MET_MICMU MET_MICMU SVDSGLHSYMEMPLECILTEK--RRKRSTREE-----VFNILQAAYVSKPGAQLAKQIGA MET_OTOGA MET_OTOGA SVDSGLHSYMEMPLECILTEK--RRKRSTRKE-----VFNILQAAYVSKPGAHLAKQIGV MET_HORSE MET_HORSE SVDSGLHSYMEMPLECILTEK--RRKRSTSEE-----VFNILQAAYVSKPGAHLAKQIGA MET_CERAE MET_CERAE SLNSGLHSYMEMPLECILTEK--RKKRSTKKE-----VFNILQAAYVSKPGAQLARQIGA MET_PAPAN MET_PAPAN SLNSGLHSYMEMPLECILTEK--RKKRSTKKE-----VFNILQAAYVSKPGAQLARQIGA MET_COLGU MET_COLGU SINSGLHSYMEMPLECILTEK--RKKRSTKKE-----VFNILQAAYVSKPGAQLARQIGA MET_HYLLE MET_HYLLE SINSGLHSYMEMPLECILTEK--RKKRSTKKE-----VFNILQAAYVSKPGAQLARQIGA MET_GORGO MET_GORGO SINSGLHSYMEMPLECILTEK--RKKRSTKKE-----VFNILQAAYVSKPGAQLARQIGA MET_PANTR MET_PANTR SINSGLHSYMEMPLECILTEK--RKKRSTKKE-----VFNILQAAYVSKPGAQLARQIGA MET_PONAB MET_PONAB SINSGLHSYMEMPLECILTEK--RKKRSTKKE-----VFNILQAAYVSKPGAQLARQIGA B4DLF5_HUMAN B4DLF5_HUMAN ------------------------------------------------------------ A1L467_HUMAN A1L467_HUMAN SINSGLHSYMEMPLECILTEK--RKKRSTKKE-----VFNILQAAYVSKPGAQLARQIGA MET_HUMAN MET_HUMAN SINSGLHSYMEMPLECILTEK--RKKRSTKKE-----VFNILQAAYVSKPGAQLARQIGA Q59EB3_HUMAN Q59EB3_HUMAN ------------------------------------------------------------ MET_CALJA MET_CALJA SINSALHSYMEMPLECILTEK--RKKRSTKKE-----VFNILQAAYVSKPGAQLARQIGA MET_CALMO MET_CALMO SINSALHSYMEMPLECILTEK--RKKRSTKKE-----VFNILQAAYVSKPGAQLARQIGA MET_SAIBB MET_SAIBB SINSALHSYMEMPLECILTEK--RKKRSTKKE-----VFNILQAAYVSKPGAQLARQIGA MET_AOTNA MET_AOTNA SINSALHSYMEMPLECILTEK--RKKRSTKKE-----VFNILQAAYVSKPGAQLARQIGA MET_ATEGE MET_ATEGE SINSALHSYMEMPLECILTEK--RKKRSTKKE-----VFNILQAAYVSKPGAQLARQIGA Q4RS82_TETNG Q4RS82_TETNG --------------SCVYGEN--------------------------------------- Q64GK4_DANRE Q64GK4_DANRE SSDSEILRYVEMPFECIYSER--RRKKRSAQV-----VFNVLQAAHVAKVGYDFQQEMGL Q08757_CHICK Q08757_CHICK AHEPELRRYREIVLDCRYESKRRRRRRGAEEETERDVAYNVLQAAHAARPGARLARDLGI B2RUR6_MOUSE B2RUR6_MOUSE AVEPEIGDYRELVLDCHFAPK--RRRRGAPEGTQ---PYPVLQAAHSAPVDAKLAVELSI RON_MOUSE RON_MOUSE AVEPEIGDYRELVLDCHFAPK--RRRRGAPEGTQ---PYPVLQAAHSAPVDAKLAVELSI Q6DTW4_CANFA Q6DTW4_CANFA ------------------------------------------------------------ RON_HUMAN RON_HUMAN ATEPELGDYRELVLDCRFAPK--RRRRGAPEGGQ---PYPVLQVAHSAPVGAQLATELSI MATCH CONSENSUS ????????Y?E??LEC????K??R??R????E??????FN?LQAA?????G??LA?????

P70003_XENLA P70003_XENLA SETDPVLFAVFAQSEPMSAQPRKYSAVCAFPISLIDLSIEDGMNACCSNTNSVRLTRGLN P79950_XENLA P79950_XENLA SETDPVLFAVFAQSEPMSAQPRKYSAVCAFPISLIDLSIEDGMNACCSNTNSVRLTRGLN Q4SR43_TETNG Q4SR43_TETNG EEEDDILYGVFAVT-DDSGVAEHDSALCAFPMDIVNTAIADGVDDCCQSGPEQLSRGLCH Q9W650_XENLA Q9W650_XENLA KPDDDILYGVFAQSKPDSPEPNNRSAVCAVSVKTINEFFNSAA-------DKQNTKCLEH A0M8T9_CHICK A0M8T9_CHICK GLNDDILYGVFAQSKPDSSEPTNRSAVCAVSVRTINEFFNKIV-------DKQNMKCLQH Q90975_CHICK Q90975_CHICK GLIDDILYGVFAQTNQIPQEPTNRSAVCAVSVRTINEFFNKIV-------DKQNMKCLQH MET_ORNAN MET_ORNAN GLNDDILYGVFAQSKPDSAEPMNRSAICAFPIKYINEFFSKIV-------NKNNVRCLQH A4FUV6_MOUSE A4FUV6_MOUSE SPSDDILFGVFAQSKPDSAEPVNRSAVCAFPIKYVNDFFNKIV-------NKNNVRCLQH MET_MOUSE MET_MOUSE SPSDDILFGVFAQSKPDSAEPVNRSAVCAFPIKYVNDFFNKIV-------NKNNVRCLQH A4FUV7_MOUSE A4FUV7_MOUSE SPSDDILFGVFAQSKPDSAEPVNRSAVCAFPIKYVNDFFNKIV-------NKNNVRCLQH MET_RAT MET_RAT SPYDDILYGVFAQSKPDSAEPMNRSAVCAFPIKYVNDFFNKIV-------NKNNVRCLQH Q2IBC7_RAT Q2IBC7_RAT SPYDDILYGVFAQSKPDSAEPMNRSAVCAFPIKYVNDFFNKIV-------NKNNVRCLQH MET_RHIFE MET_RHIFE NLDDDILYAVFAQSKPDSAEPMNRSAVCAFPIKLVNEFFNKIV-------NKNNVRCLQH MET_ATEAB MET_ATEAB SLNDDILYGVFAQSKPDSAEPMNRSAVCAFPIKYVNEFFNKIV-------NKNNVRCLQH MET_ECHTE MET_ECHTE SAHDDILYGVFSQSRPDSAEPTDRSALCAFPVKYVDEFFHRIV-------NKNNVRCLQH Q2QLD2_CARPS Q2QLD2_CARPS ------------------------------------------------------------ Q07E11_CAVPO Q07E11_CAVPO GLNDDILYGVFAQSKPDSAEPMNRSAVCAFPIKYVNEFFNKIV-------NKNNVKCLQH MET_DASNO MET_DASNO SPNDDILYGVFAQSKPDSAEPMNRSAVCAFPIKYVNEFFNKIV-------NKNNVRCLQH MET_CANFA MET_CANFA NLNDDILYGVFAQSKPDSAEPMNRSAVCAFPIKYVNEFFNKIV-------NKNNVRCLQH MET_MUSPF MET_MUSPF NLNDDILYGVFARSQPDSAEPMNRSAVCAFPIKYVNEFFNKIV-------NKNNVRCLQH MET_FELCA MET_FELCA NLNDDILYGVFAQSKPDSAEPMNRSAVCAFPIKYVNEFFNKIV-------NKNNVRCLQH MET_NEONE MET_NEONE NLNDDILYGVFAQSKPDSAEPMNRSAVCAFPIKYVNEFFNKIV-------NKNNVRCLQH MET_MUNMU MET_MUNMU NLNDDILYGVFAQSKPDSSEPMNRSAVCAFPVKYVNEFFNKIV-------NKNNVRCLQH MET_SHEEP MET_SHEEP NLNDDILYGVFAQSKPDSSEPMNRSAVCAFPVKYVNEFFNKIV-------NKNNVRCLQH MET_BOVIN MET_BOVIN SLNDDILYGVFAQSKPDSSEPMNRSAVCAFPVKYVNEFFNKIV-------NKNNVRCLQH A4D7S8_MACEU A4D7S8_MACEU ------------------------------------------------------------ MET_LOXAF MET_LOXAF LPDDDILYGVFAQSKLDSAEPMNRSAVCAFPIKYVNDFFNKIV-------NKNNVRCLQH MET_RABIT MET_RABIT TPNDDILYGVFAQSKPDSAEPMNRSAVCAFPIKYINEFFNKIV-------NKNNVKCLQH MET_PIG MET_PIG NLNDDILYGVFAQSKPDSAEPMNRSAVCAFPVKYVNEFFNKIV-------NKNNVRCLQH MET_EULMM MET_EULMM SLNDDILFGVFAQSKPDSAEPMNRSAVCAFPIKYVNEFFNKIV-------NKNNVRCLQH MET_MICMU MET_MICMU SLNDDILFGVFAQSKPDSAEPMNRSAVCAFPIKYVNDFFNKIV-------NKNNVRCLQH MET_OTOGA MET_OTOGA SVNDDILFGVFAQSKPDSAEPMNRSAVCAFPIKYVNEFFNKIV-------NKNNVRCLQH MET_HORSE MET_HORSE NLNDDILYGVFAQSKPDSAEPMNRSAVCAFPVKYVNEFFNKIV-------NKNNVRCLQH MET_CERAE MET_CERAE SLNDDILFGVFAQSKPDSAEPMDRSAMCAFPIKYVNDFFNKIV-------NKNNVRCLQH MET_PAPAN MET_PAPAN SLNDDILFGVFAQSKPDSAEPMDRSAMCAFPIKYVNDFFNKIV-------NKNNVRCLQH MET_COLGU MET_COLGU SLNDDILFGVFAQSKPDSAEPMDRSAMCAFPIKYVNDFFNKIV-------NKNNVRCLQH MET_HYLLE MET_HYLLE SLNDDILFGVFAQSKPDSAEPMDRSAMCAFPIKYVNDFFNKIV-------NKNNVRCLQH MET_GORGO MET_GORGO SLNDDILFGVFAQSKPDSAEPMDRSAMCAFPIKYVNDFFNKIV-------NKNNVRCLQH MET_PANTR MET_PANTR SLNDDILFGVFAQSKPDSAEPMDRSAMCAFPIKYVNDFFNKIV-------NKNNVRCLQH MET_PONAB MET_PONAB SLNDDILFGVFAQSKPDSAEPMDRSAMCAFPIKYVNDFFNKIV-------NKNNVRCLQH B4DLF5_HUMAN B4DLF5_HUMAN ------------------------------------------------------------ A1L467_HUMAN A1L467_HUMAN SLNDDILFGVFAQSKPDSAEPMDRSAMCAFPIKYVNDFFNKIV-------NKNNVRCLQH MET_HUMAN MET_HUMAN SLNDDILFGVFAQSKPDSAEPMDRSAMCAFPIKYVNDFFNKIV-------NKNNVRCLQH Q59EB3_HUMAN Q59EB3_HUMAN ------------------------------------------------------------ MET_CALJA MET_CALJA SLNDDILFGVFAQSKPDSAEPMDRSAVCAFPIKYVNDFFNKIV-------NKNNVRCLQH MET_CALMO MET_CALMO SLNDDILFGVFAQSKPDSAEPMDRSAVCAFPIKYVNDFFNKIV-------NKNNVRCLQH MET_SAIBB MET_SAIBB SLNDDILFGVFAQSKPDSAEPMDRSAVCAFPIKYVNDFFNKIV-------NKNNVRCLQH MET_AOTNA MET_AOTNA SLNDDILFGVFAQSKPDSAEPMDRSAVCAFPIKYVNDFFNKIV-------NKNNVRCLQH MET_ATEGE MET_ATEGE SLNDDILFGVFAQSKPDSAEPMDRSAVCAFPIKYVNDFFNKIV-------NKNNVRCLQH Q4RS82_TETNG Q4RS82_TETNG ------------------------------------------------------------ Q64GK4_DANRE Q64GK4_DANRE KEGEDVLFAAFARSKPDSPEPTASSAVCLISITDINEFFKVFI-------QKGYTRKLHH Q08757_CHICK Q08757_CHICK DGTETVLFGAFAESHPESRAPQHNSAVCAFPLRLLNQAIREGMDKCCG--TGTQTLKRGL B2RUR6_MOUSE B2RUR6_MOUSE SEGQEVLFGVFVTVKDGGSGMGPNSVVCAFPIYHLNILIEEGVEYCCHSSNSSSLLSRGL RON_MOUSE RON_MOUSE SEGQEVLFGVFVTVKDGGSGMGPNSVVCAFPIYHLNILIEEGVEYCCHSSNSSSLLSRGL Q6DTW4_CANFA Q6DTW4_CANFA ------------------------------------------------------------ RON_HUMAN RON_HUMAN AEGQEVLFGVFVTGKDGGPGVGPNSVVCAFPIDLLDTLIDEGVERCCESPVHPGLR-RGL MATCH CONSENSUS ???D??L?GVFA?S???S??P???SA?CAFP????N??????V?????????????????

P70003_XENLA P70003_XENLA FFQPEME-CP------QNDNQSDITCKNVPTLVSPPLRRVDIFNGQLDGVLLTSMYVRPQ P79950_XENLA P79950_XENLA FFQPEME-CP------QNDNQSDITCKNVPTLVSPPLRRVDIFNGQLDGVLLTSMYVRPQ Q4SR43_TETNG Q4SR43_TETNG F--QPCESCP------HESMENNATCKDQPTMVSKPYYRVDLFNRQMTDVLLTSLLVTTI Q9W650_XENLA Q9W650_XENLA FYGKDNRLCINNKRFLRNASHCSTPIDEYRVEVTTVLRRLDLFMDQFRNVLLTSISVFTQ A0M8T9_CHICK A0M8T9_CHICK FYGKDSKYCL-NRAFSRNASYCRAQDDEYRLEVTTPLQRVDLFMGQFNNILLTSISVFTK Q90975_CHICK Q90975_CHICK FYGKDSKYCL-NRAFSRNASYCRAQDDEYRLEVTTPLQRVDLFMGQFNNILLTSISVFTK MET_ORNAN MET_ORNAN FYGNHHRHCA-NRTFQWNSSGCEVRDDEYRMEFTTPLQRVDLSMGKFSHVLLTSISTFIK A4FUV6_MOUSE A4FUV6_MOUSE FYGPNHEHCF-NRTLLRNSSGCEARSDEYRTEFTTALQRVDLFMGRLNQVLLTSISTFIK MET_MOUSE MET_MOUSE FYGPNHEHCF-NRTLLRNSSGCEARSDEYRTEFTTALQRVDLFMGRLNQVLLTSISTFIK A4FUV7_MOUSE A4FUV7_MOUSE FYGPNHEHCF-NRTLLRNSSGCEARSDEYRTEFTTALQRVDLFMGRLNQVLLTSISTFIK MET_RAT MET_RAT FYGPNHEHCF-NRTLLRNSSGCEVRSDEYRTEFTTALQRVDLFMGRLNHVLLTSISTFIK Q2IBC7_RAT Q2IBC7_RAT FYGPNHEHCF-NRTLLRNSSGCEVRSDEYRTEFTTALQRVDLFMGRLNHVLLTSISTFIK MET_RHIFE MET_RHIFE FYGPNHEPCF-NRTLLRIPSGCEVRSDEYRTEFTTALQRVDLFMGQFNRVLLTSVSTFIA MET_ATEAB MET_ATEAB FYGPNHEHCF-NRTLLRNSSSCDVRSDEYRTEFTTALQRVDLFMGQFNQVLLTSISTFIK MET_ECHTE MET_ECHTE FYGPNHLHCF-NRTLLRNSSGCEVRSDEYRTEFTTALQRIDLSAGHFSQVLLTSISTFIK Q2QLD2_CARPS Q2QLD2_CARPS -------------TLLRNSSGCEVHSDEYRTEFTTALQRVDLFMGQFNQVLLTSITTFIK Q07E11_CAVPO Q07E11_CAVPO FYGPNHEHCF-NRTLLRNSSGCEVRSDEYRTEFTTALQRVDLFSGQFKQVLLTSISTFVK MET_DASNO MET_DASNO FYGPNHEHCF-NRTLLRNSSGCEVRSDEYRTEFTTALQRVDLFMGQFNQVLLTSISTFIK MET_CANFA MET_CANFA FYGPNHEHCF-NRTLLRNSSGCEARNDEYRTEFTTALQRVDLFMGQFNQVLLTSISTFIK MET_MUSPF MET_MUSPF FYGPNHEHCF-NRTLLRNSSGCEVRSDEYRTEFTTALQRVDLFMGQFNQVLLTSISTFIK MET_FELCA MET_FELCA FYGPNHEHCF-NRTLLRNSSGCEVRSDEYRTEFTTALQRVDLFMGQFNQVLLTSISTFIK MET_NEONE MET_NEONE FYGPNHEHCF-NRTLLRNSSGCEVRSDEYRTEFTTALQRVDLFMGQFNQVLLTSISTFIK MET_MUNMU MET_MUNMU FYGPNHEHCF-NRTLLRNSSGCEVRSDEYRTEFTTALPRVDLFTGQFNQVLLTSISTFIK MET_SHEEP MET_SHEEP FYGPNHEHCF-NRTLLRNSSGCEVRNDEYRTEFTTALPRIDLFMGQFNQVLLTSISTFIK MET_BOVIN MET_BOVIN FYGPNHEHCF-NRTLLRNSSGCEVRNDEYRTEFTTALPRVDLFTGQFNQVLLTSISTFIK A4D7S8_MACEU A4D7S8_MACEU ------------------------------------------------------------ MET_LOXAF MET_LOXAF FYGPNHEHCF-NRTLLRNSSGCEVRRDEYRTEFTTALQRVDLFTGQFNQVLLTSISTFIK MET_RABIT MET_RABIT FYGPNHEHCF-NRTLLRNSSDCEARSDEYRTELTTALQRVDLFMGQFNQVLLTSISTFIK MET_PIG MET_PIG FYGPNHEHCF-NRTLLRNSSGCEVRSDEYRTEFTTALQRIDLFMGQFNQVLLTSISTFIK MET_EULMM MET_EULMM FYGPHHEHCF-NRTLLRNSSGCEVRRDEYRTEFTTAFQRVDLFMGQFNQVLLTSISTFIK MET_MICMU MET_MICMU FYGPHHEHCF-NRTLLRNSSGCEVRKDEYRTEFTTALQRVDLFMGQFNQVLLTSISTFIK MET_OTOGA MET_OTOGA FYGPNHEHCF-NRTLLRNSSGCEVRSDEYRTEFTTALQRVDLFMGQFNQVLLTSISTFIK MET_HORSE MET_HORSE FYGPHHEHCF-NRTLLRNSSGCEVRNDEYRTEFTTALQRVDLFMGQFNQVLLTSISTFIK MET_CERAE MET_CERAE FYGPNHEHCF-NRTLLRNSSGCEARRDEYRAEFTTALQRVDLFMGQFSEVLLTSISTFVK MET_PAPAN MET_PAPAN FYGPNHEHCF-NRTLLRNSSGCEARRDEYRAEFTTALQRVDLFMGQFSEVLLTSISTFVK MET_COLGU MET_COLGU FYGPNHEHCF-NRTLLRNSSGCEARRDEYRAEFTTALQRVDLFMGQFSEVLLTSISTFVK MET_HYLLE MET_HYLLE FYGPNHEHCF-NRTLLRNSSGCEARRDEYRTEFTTALQRVDLFMGQFSEVLLTSVSTFIK MET_GORGO MET_GORGO FYGPNHEHCF-NRTLLRNSSGCEARRDEYRTEFTTALQRVDLFMGQFSEVLLTSISTFIK MET_PANTR MET_PANTR FYGPNHEHCF-NRTLLRNSSSCEARRDEYRTEFTTALQRVDLFMGQFSEVLLTSISTFIK MET_PONAB MET_PONAB FYGPNHEHCF-NRTLLRNSSGCEARRDEYRTEFTTALQRVDLFMGQFSEVLLTSISTFIK B4DLF5_HUMAN B4DLF5_HUMAN -------------------------------------------MGQFSEVLLTSISTFIK A1L467_HUMAN A1L467_HUMAN FYGPNHEHCF-NRTLLRNSSGCEARRDEYRTEFTTALQRVDLFMGQFSEVLLTSISTFIK MET_HUMAN MET_HUMAN FYGPNHEHCF-NRTLLRNSSGCEARRDEYRTEFTTALQRVDLFMGQFSEVLLTSISTFIK Q59EB3_HUMAN Q59EB3_HUMAN ------------------------------------------------------------ MET_CALJA MET_CALJA FYGPNHEHCF-NRTFQRNLLGCEARHDEYRTEFTTALQRIDLFAGQFNKVLLTSISTFIK MET_CALMO MET_CALMO FYGPNHEHCF-NRTFQRNLLGCEARRDEYRTEFTTALQRIDLFAGQFNKVLLTSISTFVK MET_SAIBB MET_SAIBB FYGPNHEHCF-NRTFQRNFLGCETRRDEYRTEFTTALQRIDLFAGQFNKVLLTSISTFVK MET_AOTNA MET_AOTNA FYGPNHEHCF-NRTFQRNLLGCEARRDEYRTEFTTALQRIDLFAGQFNKVLLTSISTFVK MET_ATEGE MET_ATEGE FYGPNHEHCF-NRTFQRNLLGCEARRDEYRTEFTTALQRIDLFAGQFNKVLLTSISTFVK Q4RS82_TETNG Q4RS82_TETNG ------------------------------------------------------------ Q64GK4_DANRE Q64GK4_DANRE FPGSEEKTF--NQTFVGDSFSCGKHERGYRLEVTSTNPRRDYFHGRFRNVLLTSIAVVPI Q08757_CHICK Q08757_CHICK AFFQPQQYC--PHSVNLSAPVTNTSCWDQPTLVPAASHKVDLFNGRLSGTLLTSIFVTVL B2RUR6_MOUSE B2RUR6_MOUSE DFFQTPSFC--PNPPGGEASGPSSRCHYFPLMVHASFTRVDLFNGLLGSVKVTALHVTRL RON_MOUSE RON_MOUSE DFFQTPSFC--PNPPGGEASGPSSRCHYFPLMVHASFTRVDLFNGLLGSVKVTALHVTRL Q6DTW4_CANFA Q6DTW4_CANFA ------------NPPGLEAPSLNTSCRHFPLLVTGSLSRVDLFNGLLGPVQVTALHVTRL RON_HUMAN RON_HUMAN DFFQSPSFC--PNPPGLEALSPNTSCRHFPLLVSSSFSRVDLFNGLLGPVQVTALYVTRL MATCH CONSENSUS F???????C????????????????????????T??L?R?DLF?G????VLLTS??????

P70003_XENLA P70003_XENLA EDLTIGFLGTSVGRLLQVVLQRNSKPRTLS-NFSISDT-HPVSREV--TRIRD---SLFF P79950_XENLA P79950_XENLA EDLTIGFLGTSVGRLLQVVLQRNSKPRTLS-NFSISDT-HPVSREV--TRIRD---SLFF Q4SR43_TETNG Q4SR43_TETNG ENKTVAHIGTSTGRLLQLVLTRSSPIIFA--NYSLVE--NQRVSSIAAVYSSE---YLLF Q9W650_XENLA Q9W650_XENLA GRLTIANLGTSEGRFMQVIISRTGQPKPHV-NFLLEA--RPISPEIVINTASEESGYTLV A0M8T9_CHICK A0M8T9_CHICK GNLTIANLGTSEGRFMQIVVSRSEPTAPHV-SFQLDS--HAVSPQVVVEQSAAADGYTLV Q90975_CHICK Q90975_CHICK GNLTIANLGTSEGRFMQIVVSRSEPTAPHV-SFQLDS--HAVSPQVVVEQSAAADGYTLV MET_ORNAN MET_ORNAN GNLTVANLGTAEGRFMQVVISRSDPPSPHV-DFLLDN--HPVSPEVIVVNSSMPDGYTLV A4FUV6_MOUSE A4FUV6_MOUSE GDLTIANLGTSEGRFMQVVLSRTAHLTPHV-NFLLDS--HPVSPEVIVEHPSNQNGYTLV MET_MOUSE MET_MOUSE GDLTIANLGTSEGRFMQVVLSRTAHLTPHV-NFLLDS--HPVSPEVIVEHPSNQNGYTLV A4FUV7_MOUSE A4FUV7_MOUSE GDLTIANLGTSEGRFMQVVLSRTAHLTPHV-NFLLDS--HPVSPEVIVEHPSNQNGYTLV MET_RAT MET_RAT GDLTIANLGTSEGRFMQVVLSRTAHFTPHV-NFLLDS--YPVSPEVIVEHPSNQNGYTLV Q2IBC7_RAT Q2IBC7_RAT GDLTIANLGTSEGRFMQVVLSRTAHFTPHV-NFLLDS--YPVSPEVIVEHPSNQNGYTLV MET_RHIFE MET_RHIFE GDLTIANLGTSEGRFMQVVVFRSGSSTPHV-NFRLDS--HPVSPEMIVQHPLNQNGYTLV MET_ATEAB MET_ATEAB GDLTIANLGTSEGRFMQVVVSRLGSSTPHV-NFRLDS--HPVSPEVIVEHPLNGNDYTLV MET_ECHTE MET_ECHTE GDLTIANLGTSEGRFMQVVVSRSGSWTPHV-DFRLDS--HAVSPEVIVEHPVNQNGYTLV Q2QLD2_CARPS Q2QLD2_CARPS GDLTIANLGTSEGRFLQVVVSRSGSSTPHV-NFRLDS--HPVSPEAIVEHPLNQNGYTLV Q07E11_CAVPO Q07E11_CAVPO GDLTIANLGTSEGRFMQVVVSRTVSSTPHV-NFRLDS--QPVSPEVIVEQPLNQNGYTLV MET_DASNO MET_DASNO GDLTIANLGTSEGRFMQVVVSRSVLPAPHV-NFLLDS--NPVSLEALVEDPVNQNGYTLV MET_CANFA MET_CANFA GDLTIANLGTSEGRFMQVVVSRSGLSTPHV-NFRLDS--HPVSPEAIVEHPLNQNGYTLV MET_MUSPF MET_MUSPF GDLTIANLGTSEGRFMQVVVSRSGSSTPHV-NFRLDS--HPVSPEAIVEHPLNQNGYTLV MET_FELCA MET_FELCA GDLTIANLGTSEGRFMQVVVSRSGSSTPHV-NFRLDS--HPVSSEAIVEHPLNQNGYTLV MET_NEONE MET_NEONE GDLTIANLGTSEGRFMQVVVSRSGSSTPHV-NFRLDS--HPVSSEAIVEHPLNQNGYTLV MET_MUNMU MET_MUNMU GDLTIANLGTSEGRFMQVVVSRSGSLTPHV-NFRLDS--HPVSPEVIVEHPPNQNGYTLV MET_SHEEP MET_SHEEP GDLTIANLGTSEGRFMQVVVSRSGSLTPHV-NFPLDS--HPVSPEVVVEHPLNQNGYTLV MET_BOVIN MET_BOVIN GDLTIANLGTSEGRFMQVVVSRSGSLTPHV-NFHLDS--HPVSPEVIVEHPLNQNGYTLV A4D7S8_MACEU A4D7S8_MACEU ------------------------------------------------------------ MET_LOXAF MET_LOXAF GNLTIANLGTSEGRFMQVVVSRSGLTTPHV-NFRLDS--HAVSPEVILEHPLNQNGYTLV MET_RABIT MET_RABIT GDLTIANLGTSEGRFMQVVISRTILNVPHV-NFRLDS--HPVSPEVVVEHPLNQNGYTLV MET_PIG MET_PIG GDLTIANLGTSEGRFMQVVVSRPGLSTPHV-NFHLDS--HPVSPEVIVE-PLNQNGYTLV MET_EULMM MET_EULMM GDLTIANLGTSEGRFMQVVVSRSGSSTPHV-NFQLDS--HPVSPEVIVEHPLNQNGYTLV MET_MICMU MET_MICMU GDLTIANLGTSEGRFMQVVVSRSGSSTPHV-NFQLDS--HPVSPEVIVEHPLNQNGYTLV MET_OTOGA MET_OTOGA GDLTIANLGTSEGRFMQIMVSRSGSSTPHV-NFHLDS--HPVSPEVIVEHTVNQNGYTLV MET_HORSE MET_HORSE GNLTIANLGTSEGRFMQVVVSRSGSSTPHV-NFHLDS--HPVSPEVIVEHPLNQNGYTLV MET_CERAE MET_CERAE GDLTIANLGTSEGRFMQVVVSRSGPSTPHV-NFLLDS--HPVSPEVIVEHPLNQNGYTLV MET_PAPAN MET_PAPAN GDLTIANLGTSEGRFMQVVVSRSGPSTPHV-NFLLDS--HPVSPEVIVEHPLNQNGYTLV MET_COLGU MET_COLGU GDLTIANLGTSEGRFMQVVVSRSGPSTPHV-NFLLDS--HPVSPEVIVEHPLNQNGYTLV MET_HYLLE MET_HYLLE GDLTIANLGTSEGRFMQVVVSRSGPSTPHV-NFLLDS--HPVSPEVIVEHPLNQNGYTLV MET_GORGO MET_GORGO GDLTIANLGTSEGRFMQVVVSRSGPSTPHV-NFLLDS--HPVSPEVIVEHTLNQNGYTLV MET_PANTR MET_PANTR GDLTIANLGTSEGRFMQVVVSRSGPSTPHV-NFLLDS--HPVSPEVIVEHTLNQNGYTLV MET_PONAB MET_PONAB GDLTIANLGTSEGRFMQVVVSRSGPSTPHV-NFLLDS--HPVSPEVIVEHPLNQNGYTLV B4DLF5_HUMAN B4DLF5_HUMAN GDLTIANLGTSEGRFMQVVVSRSGPSTPHV-NFLLDS--HPVSPEVIVEHTLNQNGYTLV A1L467_HUMAN A1L467_HUMAN GDLTIANLGTSEGRFMQVVVSRSGPSTPHV-NFLLDS--HPVSPEVIVEHTLNQNGYTLV MET_HUMAN MET_HUMAN GDLTIANLGTSEGRFMQVVVSRSGPSTPHV-NFLLDS--HPVSPEVIVEHTLNQNGYTLV Q59EB3_HUMAN Q59EB3_HUMAN ----------------------------------LD------------------------ MET_CALJA MET_CALJA GDLTIANLGTSEGRFIQIVVSRSVPSNPHV-NFLLDS--HPVSPEVIVEHPLNQNGYTLV MET_CALMO MET_CALMO GDLTIANLGTSEGRFIQIVVSRSVPSTPHV-NFLLDS--HPVSPEVIVEQPLNQDGYTLV MET_SAIBB MET_SAIBB GDLTIANLGTSEGRFIQIVVSRSVPSTPHV-NFLLDS--HPVSPEVIVEHPLNHNGYTLV MET_AOTNA MET_AOTNA GDLTIANLGTSEGRFIQIVVSRSVPSTPHV-NFLLDF--HPVSPEVIVEHPLNQNGYTLV MET_ATEGE MET_ATEGE GDLTIANLGTSEGRFIQIVVSRSVPSTPHV-NFLLDS--HPVSPEVIVEHPLNQNGYTLV Q4RS82_TETNG Q4RS82_TETNG ------------------------------------------------------------ Q64GK4_DANRE Q64GK4_DANRE QNHTVVSLGTAEGRVIQVVVSRFGKTEPHV-DFRLDM--LPVSSEMALLSPQHHNGSLLL Q08757_CHICK Q08757_CHICK QNVTVAHLGTAQGRVLQMVLQRSSSYVVALTNFSLGE------PGLVQHATGLQGHSLLF B2RUR6_MOUSE B2RUR6_MOUSE GNVTVAHMGTVDGRVLQVEIARSLNYLLYVSNFSLGSSGQPVHRDV--SRLGN---DLLF RON_MOUSE RON_MOUSE GNVTVAHMGTVDGRVLQVEIARSLNYLLYVSNFSLGSSGQPVHRDV--SRLGN---DLLF Q6DTW4_CANFA Q6DTW4_CANFA NNVTVAHMGTADGRILQVELVRSLNYLLFVSNFSLGNNGQPTQRDV--SRLGD---HLFF RON_HUMAN RON_HUMAN DNVTVAHMGTMDGRILQVELVRSLNYLLYVSNFSLGDSGQPVQRDV--SRLGD---HLLF MATCH CONSENSUS G?LTIA?LGTSEGR??Q?V??R?????PHV?NF?LD????PVS?E???????????Y?L?

P70003_XENLA P70003_XENLA ITGNQ-----------VTKVNITGPGCRHFLTCSRCLRAPRFMGCSWCK--NVCCQQGEC P79950_XENLA P79950_XENLA ITGNQ-----------VTKVNITGPGCRHFLTCSRCLRAPRFMGCSWCK--NVCCQQGEC Q4SR43_TETNG Q4SR43_TETNG VVGDKHVIVSTISLCQMIRVPQRGPGCQHFLTCAMCLMAPQFMGCGWCS--GVCSWENQC Q9W650_XENLA Q9W650_XENLA NTGMQ-----------IIKVPLVVLTCGHLKSCSHCLSSPS-VNCGWSK--NHCSTKQEC A0M8T9_CHICK A0M8T9_CHICK VTGKK-----------ITKVPLNGPGCHHFQSCSQCLLAPAFMRCGWCG--QQCLRAPEC Q90975_CHICK Q90975_CHICK VTGKK-----------ITKVPLNGPGCHHFQSCSQCLLAPAFMRCGWCG--QQCLRAPEC MET_ORNAN MET_ORNAN ITGKK-----------ITKIPLNGLGCDHFKSCRQCLSAPSFVQCGWCD--DRCTTAEKC A4FUV6_MOUSE A4FUV6_MOUSE VTGKK-----------ITKIPLNGLGCGHFQSCSQCLSAPYFIQCGWCH--NQCVRFDEC MET_MOUSE MET_MOUSE VTGKK-----------ITKIPLNGLGCGHFQSCSQCLSAPYFIQCGWCH--NQCVRFDEC A4FUV7_MOUSE A4FUV7_MOUSE VTGKK-----------ITKIPLNGLGCGHFQSCSQCLSAPYFIQCGWCH--NQCVRFDEC MET_RAT MET_RAT VTGKK-----------ITKIPLNGLGCGHFQSCSQCLSPPYFIQCGWCH--NRCVHSNEC Q2IBC7_RAT Q2IBC7_RAT VTGKK-----------ITKIPLNGLGCGHFQSCSQCLSAPYFIQCGWCH--NRCVHSNEC MET_RHIFE MET_RHIFE VTGKT-----------ITKIPLNGLGCEHFQSCSQCLSAPPFVQCGWCH--NKCVRSEEC MET_ATEAB MET_ATEAB VTGKK-----------ITKIPLNGLGCEHFQSCSQCLSAPAFVQCGWCH--DKCVQLEEC MET_ECHTE MET_ECHTE VTGKK-----------ITKIPLDGLGCEHFQSCSQCLSAPPFVQCGWCH--DKCARAEDC Q2QLD2_CARPS Q2QLD2_CARPS VTGKK-----------ITKIPLNGLGCEHFQSCSQCLSAPPFVQCGWCH--DKCVRLETC Q07E11_CAVPO Q07E11_CAVPO ITGKK-----------ITKIPLNGLGCGHFQSCSQCLSAPSFVQCGWCH--NQCVRSDEC MET_DASNO MET_DASNO VTGKK-----------ITRIPLDGLGCGHFQSCSQCLSAPPFVQCGWCQ--DKCVQVEEC MET_CANFA MET_CANFA VTGKK-----------ITRIPLNGLGCEHFQSCSQCLSAPPFVQCGWCH--DRCVHLEEC MET_MUSPF MET_MUSPF VTGKK-----------ITKIPLNGLGCEHFQSCSQCLSAPPFVQCGWCH--DKCVQLEEC MET_FELCA MET_FELCA VTGKK-----------ITKIPLNGLGCEHFQSCSQCLSAPPFVQCGWCH--DKCVQLEEC MET_NEONE MET_NEONE VTGKK-----------ITKIPLNGLGCEHFQSCSQCLSAPPFVQCGWCH--DKCVQLEEC MET_MUNMU MET_MUNMU VTGKK-----------ITKIPLNGLGCEHFQSCSQCLSAPSFVQCGWCR--DKCVRLEEC MET_SHEEP MET_SHEEP VTGKK-----------ITKIPLNGLGCEHFQSCSQCLSAPSFVQCGWCH--DKCVRLEEC MET_BOVIN MET_BOVIN VTGKK-----------ITKIPLNGLGCEHFQSCSQCLSAPSFVQCGWCH--DKCVRLEEC A4D7S8_MACEU A4D7S8_MACEU ------------------------------------------------------------ MET_LOXAF MET_LOXAF ITGKK-----------ITKIPLDGLGCDHFQSCSQCLSAPSFVQCGWCH--NKCARAEEC MET_RABIT MET_RABIT VTGNK-----------ITKIPLNGLGCGHFQSCSQCLSAPPFVQCGWCH--DKCVPSEEC MET_PIG MET_PIG VTGKK-----------ITKIPLNGLGCEHFQSCSQCLSAPPFVQCGWCQ--DKCVQLEEC MET_EULMM MET_EULMM VTGKK-----------ITKIPLNGLGCGHFQSCSQCLFAPSFVQCGWCH--DKCVRSEEC MET_MICMU MET_MICMU VTGKR-----------ITKIPLNGLGCGHFQSCSQCLSAPSFVQCGWCH--DKCVRSEEC MET_OTOGA MET_OTOGA VTGKK-----------ISKIPLNGLGCEHFQSCSQCLSAPPFVQCGWCH--DKCVRSEEC MET_HORSE MET_HORSE VTGKK-----------ITKIPLNGLGCEHFQSCSQCLSAPPFVQCGWCH--DKCVRLEEC MET_CERAE MET_CERAE VTGKK-----------ITKIPLNGLGCRHFQSCSQCLSAPPFVQCGWCH--DKCVRSEEC MET_PAPAN MET_PAPAN VTGKK-----------ITKIPLNGLGCRHFQSCSQCLSAPPFVQCGWCH--DKCVRSEEC MET_COLGU MET_COLGU VTGKK-----------ITKIPLNGLGCRHFQSCSQCLSAPPFVQCGWCQ--DKCVRSEDC MET_HYLLE MET_HYLLE VTGKK-----------ITKIPLSGLGCRHFQSCSQCLSAPPFVQCGWCH--DKCVRSEEC MET_GORGO MET_GORGO VTGKK-----------ITKIPLNGLGCRHFQSCSQCLSAPPFVQCGWCH--DKCVRSEEC MET_PANTR MET_PANTR VTGKK-----------ITKIPLNGLGCRHFQSCSQCLSAPPFVQCGWCH--DKCVRSEEC MET_PONAB MET_PONAB VTGKK-----------ITKIPLNGLGCRHFQSCSQCLSAPPFVQCGWCH--DKCVRSEEC B4DLF5_HUMAN B4DLF5_HUMAN ITGKK-----------ITKIPLNGLGCRHFQSCSQCLSAPPFVQCGWCH--DKCVRSEEC A1L467_HUMAN A1L467_HUMAN ITGKK-----------ITKIPLNGLGCRHFQSCSQCLSAPPFVQCGWCH--DKCVRSEEC MET_HUMAN MET_HUMAN ITGKK-----------ITKIPLNGLGCRHFQSCSQCLSAPPFVQCGWCH--DKCVRSEEC Q59EB3_HUMAN Q59EB3_HUMAN ------------------------------------------------------------ MET_CALJA MET_CALJA VTGKK-----------ITKIPLNGLGCRHFQSCSQCLSAPSFVQCGWCH--DKCVRSEEC MET_CALMO MET_CALMO VTGKK-----------ITKIPLNGLGCRHFQSCSQCLSAPSFVQCGWCH--DKCVRSEEC MET_SAIBB MET_SAIBB VTGKK-----------ITKIPLNGLGCRHFQSCSQCLSAPSFVQCGWCH--DKCVRSEEC MET_AOTNA MET_AOTNA VTGKK-----------ITKIPLNGLGCRHFQSCSQCLSAPSFVQCGWCH--DKCVQSEEC MET_ATEGE MET_ATEGE VTGKK-----------ITKIPLNGLGCRHFQSCSQCLSAPSFVQCGWCH--DKCVRSEEC Q4RS82_TETNG Q4RS82_TETNG ------------------------------------------------------------ Q64GK4_DANRE Q64GK4_DANRE ITGDK-----------VSKLPVIGPGCEQLWTCSSCLLAPGFMGCGWCRTSNRCTRAPRC Q08757_CHICK Q08757_CHICK AAGTK-----------VWRVNVTGPGCRHFSTCDRCLRAERFMGCGWCG--NGCTRHHEC B2RUR6_MOUSE B2RUR6_MOUSE ASGDQ-----------VFKVPIQGPGCRHFLTCWRCLRAQRFMGCGWCG--DRCDRQKEC RON_MOUSE RON_MOUSE ASGDQ-----------VFKVPIQGPGCRHFLTCWRCLRAQRFMGCGWCG--DRCDRQKEC Q6DTW4_CANFA Q6DTW4_CANFA ASGDQ-----------VFQVPIQGPGCHHFLTCGSCLRAQRFMGCGWCG--GMCGRQKEC RON_HUMAN RON_HUMAN ASGDQ-----------VFQVPIRGPGCRHFLTCGRCLRAWHFMGCGWCG--NMCGQQKEC MATCH CONSENSUS ?TG???????????????K?P??G?GC?HF??CS?CL?AP?F??CGWC?????C????EC

P70003_XENLA P70003_XENLA E-GECAQNTCLPSIVEFYPRTAPLRGNTNITLCGRDFQSSIVYNAPPKAKITA---ETHR P79950_XENLA P79950_XENLA E-GECAQNTCLPSIAEFYPRTAPLRGNTNITLCGRDFQSSIVYNAPPKAKITA---ETHR Q4SR43_TETNG Q4SR43_TETNG D-DRWRNESCPPGIAGFFPRTAPPDGQTELTVFGWEF------QSPLRPAITS---RTHQ Q9W650_XENLA Q9W650_XENLA LNEEWIQETCPPAVYEVFPSSAPLEGGTQLTICGSDF------VLSKNNNFDL---KNTV A0M8T9_CHICK A0M8T9_CHICK NGGTWTQETCLPRVYEILPSSAPLEGGTKLTLCGWDF------GFSKNNRFEL---RNTV Q90975_CHICK Q90975_CHICK NGGTWTQETCLPRVYEILPSSAPLEGGTKLTLCGWDF------GFSKNNRFEL---RNTV MET_ORNAN MET_ORNAN DYGLWTQDTCPPTIFEIIPSSAPLEGGTMLTVCGWDF------GFQKNNKFEL---RKTK A4FUV6_MOUSE A4FUV6_MOUSE PSGTWTQEICLPAVYKVFPTSAPLEGGTVLTICGWDF------GFRKNNKFDL---RKTK MET_MOUSE MET_MOUSE PSGTWTQEICLPAVYKVFPTSAPLEGGTVLTICGWDF------GFRKNNKFDL---RKTK A4FUV7_MOUSE A4FUV7_MOUSE PSGTWTQEICLPAVYKVFPTSAPLEGGTVLTICGWDF------GFRKNNKFDL---RKTK MET_RAT MET_RAT PSGTWTQEICLPAVYKVFPTSAPLEGGTMLTICGWDF------GFKKNNKFDL---RKTK Q2IBC7_RAT Q2IBC7_RAT PSGTWTQEICLPAVYKVFPTSAPLEGGTMLTICGWDF------GFKKNNKFDL---RKTK MET_RHIFE MET_RHIFE PSGVWTQDVCHPTIYEVFPTTAPLEGGTTLTICGWDF------GFRRNNKFDL---KKTR MET_ATEAB MET_ATEAB PSGTWTQETCLPTIYKVLPTSAPLEGGTTLTICGWDF------GFRRNNKFDL---KKTR MET_ECHTE MET_ECHTE PNGTWTQEICLPTIYEVFPASAPLEGGTTLTVCGWDF------GFRRNNKSDF---KRTR Q2QLD2_CARPS Q2QLD2_CARPS PSGAWTQEICHPTVYEVFPTSAPLEGGTTLTICGWDF------GFRRNSKFDL---KKTR Q07E11_CAVPO Q07E11_CAVPO TNGIWTQEICLPAIYKIFPTSAPIEGGTTLTICGWDF------GFRKNNKFDL---KKTK MET_DASNO MET_DASNO PNGTWTQEICLPTVYEVFPTSAPLEGGTMLTICGWDF------GFRRNNKFDL---KKTR MET_CANFA MET_CANFA PTGAWTQEVCLPAIYEVFPTSAPLEGGTVLTVCGWDF------GFRRNNKFDL---KKTK MET_MUSPF MET_MUSPF PTGTWTQEICLPTIYEVFPTSAPLEGGTMLTICGWDF------GFRRNNKFDL---KKTK MET_FELCA MET_FELCA PSGTWTQEICLPTIYEVFPTSAPLEGGTMLTVCGWDF------GFRRNNKFDL---KKTR MET_NEONE MET_NEONE PSGTWTQEICLPTIYEVFPTSAPLEGGTMLTVCGWDF------GFRRNNKFDL---KKTR MET_MUNMU MET_MUNMU PSGTWTQETCLPAIYKVFPTSAPLEGGTTLTVCGWDF------GFKRNNKFDL---KKTR MET_SHEEP MET_SHEEP PSGRWTQETCLPTIYKVFPTSAPLEGGTTLTVCGWDF------GFKRNNKFDL---KKTR MET_BOVIN MET_BOVIN SSGTWTQETCLPTIYKVFPTSAPLEGGTTLTVCGWDF------GFKRNNKFDL---KKTR A4D7S8_MACEU A4D7S8_MACEU ------------------------------------------------------------ MET_LOXAF MET_LOXAF PNGMWTQEICLPTIYEVFPTSAPLEGGTTLTVCGWDF------GFRRNNKFDL---KKTR MET_RABIT MET_RABIT PSGTWTQEICLPAIYKVFPASAPLEGGTTLTICGWDF------GFRKNNKFDL---KKTK MET_PIG MET_PIG PSGTWTQEICLPTVYKVFPTSAPLEGGTTLTICGWDF------GFRRNNKFDL---RKTK MET_EULMM MET_EULMM PSGIWTQEICLPAIHKVFPTSAPLEGGTMLTICGWDF------GFRRNNKFDL---KKTR MET_MICMU MET_MICMU PTGTWTQEICLPAIHKVFPTSAPLEGGTMLTICGWDF------GFRRNNKFDL---KKTK MET_OTOGA MET_OTOGA PSGSWTQETCRPAVHKVFPTSAPLEGGTRLTICGWDF------GFRRNNKFDL---KKTR MET_HORSE MET_HORSE HNGTWTQEICLPTIYKVFPTSAPLEGGTTLTVCGWDF------GFRKNNKLDS---KKTK MET_CERAE MET_CERAE PSGTWTQQICLPAIYKVFPTSAPLEGGTRLTICGWDF------GFRRNNKFDL---KKTR MET_PAPAN MET_PAPAN PSGTWTQQICLPAIYKVFPTSAPLEGGTRLTICGWDF------GFRRNNKFDL---KKTR MET_COLGU MET_COLGU PSGTWTQQICLPAIYKVFPTSAPLEGGTRLTICGWDF------GFRRNNKFDL---KKTR MET_HYLLE MET_HYLLE PSGTWTQQICLPAIYKVFPNSAPLEGGTRLTICGWDF------GFRRNNKFDL---KKTR MET_GORGO MET_GORGO LSGTWTQQICLPAIYKVFPNSAPLEGGTRLTICGWDF------GFRRNNKFDL---KKTR MET_PANTR MET_PANTR LSGTWTQQICLPAIYKVFPNSAPLEGGTRLTICGWDF------GFRRNNKFDL---KKTR MET_PONAB MET_PONAB SSGTWTQQICLPAIYKVFPSSAPLEGGTRLTICGWDF------GFRRNNKFDL---KKTR B4DLF5_HUMAN B4DLF5_HUMAN LSGTWTQQICLPAIYKVFPNSAPLEGGTRLTICGWDF------GFRRNNKFDL---KKTR A1L467_HUMAN A1L467_HUMAN LSGTWTQQICLPAIYKVFPNSAPLEGGTRLTICGWDF------GFRRNNKFDL---KKTR MET_HUMAN MET_HUMAN LSGTWTQQICLPAIYKVFPNSAPLEGGTRLTICGWDF------GFRRNNKFDL---KKTR Q59EB3_HUMAN Q59EB3_HUMAN ------------------------------------------------------------ MET_CALJA MET_CALJA SSGTWTQETCLPTIYKVFPTSAPLEGGTRLTICGWDF------GFRRNNKFDL---KKTR MET_CALMO MET_CALMO SSGTWTQETCLPAIYKVFPTSAPLEGGTRLTICGWDF------GFRRNNKFDL---KKTR MET_SAIBB MET_SAIBB SSGTWTQETCLPTIYKVFPTSAPLEGGTRLTICGWDF------GFRRNNKFDL---KKTR MET_AOTNA MET_AOTNA SSGTWTQETCLPTIYKVFPTSAPLEGGTRLTICGWDF------GFRRNNKFDL---KKTR MET_ATEGE MET_ATEGE SSGTWTQETCLPTIYRVFPTSAPLEGGTRLTICGWDF------GFRRNNKFDL---KKTR Q4RS82_TETNG Q4RS82_TETNG ------------------------------------------------------------ Q64GK4_DANRE Q64GK4_DANRE PQSQWIQDSCPLLITSISPSSAPLRGQTNITICGKNF------GFNKKDRFDT---KLVD Q08757_CHICK Q08757_CHICK A-GPWVQDSCPPVLTDFHPRSAPLRGQTRVTLCGMTF------HSPPDPTAHHSLPGPYR B2RUR6_MOUSE B2RUR6_MOUSE P-GSWQQDHCPPEISEFYPHSGPLRGTTRLTLCGSNF------YLRPDDVVPE---GTHQ RON_MOUSE RON_MOUSE P-GSWQQDHCPPEISEFYPHSGPLRGTTRLTLCGSNF------YLRPDDVVPE---GTHQ Q6DTW4_CANFA Q6DTW4_CANFA P-GSWQQDHCPPKLTEFYPQSGPLRGSTRLTLCGSNF------HLRPADLVHE---GTHH RON_HUMAN RON_HUMAN P-GSWQQDHCPPKLTEFHPHSGPLRGSTRLTLCGSNF------YLHPSGLVPE---GTHQ MATCH CONSENSUS ??G?W?Q??C?P??????P?SAPL?G?T?LT?CG?DF???????????????????????

P70003_XENLA P70003_XENLA VSVGPRKCIVNPGKSSS-------------TSLVCTLQTEGPPDTLSTADISLTIDENLM P79950_XENLA P79950_XENLA VSVGPRKCIVNPGKSSS-------------TSLVCTLQTEGPPDTLSTADISLTIDENLM Q4SR43_TETNG Q4SR43_TETNG VRLGHTACTVLPAKSNNTQLIFH-KRLVLLHSLVCKIRIRTTE-LFTPVNITVEVHEGKA Q9W650_XENLA Q9W650_XENLA VIIGKKRCKIEGKFSNQ-------------NKLVCRTDSSVSS----VFNMSSSVSNG-- A0M8T9_CHICK A0M8T9_CHICK VHIGGQICALEAKSSNK-------------NKLECTAPAAKNA----SFNISSSVSVG-- Q90975_CHICK Q90975_CHICK VHIGGQICALEAKSSNK-------------NKLECTAPAAKNA----SFNISSSVSVG-- MET_ORNAN MET_ORNAN VLVGNQSCTLFFNESST-------------NKLKCTAGPSTQP----RLNISISVSNA-- A4FUV6_MOUSE A4FUV6_MOUSE VLLGNESCTLTLSESTT-------------NTLKCTVGPAMSE----HFNVSVIISNS-- MET_MOUSE MET_MOUSE VLLGNESCTLTLSESTT-------------NTLKCTVGPAMSE----HFNVSVIISNS-- A4FUV7_MOUSE A4FUV7_MOUSE VLLGNESCTLTLSESTT-------------NTLKCTVGPAMSE----HFNVSVIISNS-- MET_RAT MET_RAT VLLGNESCTLTLSESTT-------------NTLKCTVGPAMSE----HFNVSVIVSNS-- Q2IBC7_RAT Q2IBC7_RAT VLLGNESCTLTLSESTT-------------NTLKCTVGPAMSE----HFNVSVIVSNS-- MET_RHIFE MET_RHIFE ILLGNESCTLTLSESTA-------------NTLKCTVGPAMSE----HLNLSIIISSG-- MET_ATEAB MET_ATEAB VFLGNESCTVTLSESST-------------NMLKCTVGPALYE----HFNMSIIISNS-- MET_ECHTE MET_ECHTE VLIGNESCPLTLSESTP-------------NMLKCTVGPAMSE----HSNLSIIISNV-- Q2QLD2_CARPS Q2QLD2_CARPS ILLGNESCTLTLSESTT-------------NMLKCTVAPAVNE----HFNMSIMISSD-- Q07E11_CAVPO Q07E11_CAVPO VFLGNESCTLTSSESTT-------------NMLKCTVGPSVNE----HFNMSILVSNN-- MET_DASNO MET_DASNO VLVGNESCTLTLSESTT-------------NTLKCTVGHAMNE----NFNMSIIISNG-- MET_CANFA MET_CANFA VFLGNESCTLTLSESTT-------------NMLKCTVGPAVNE----HFNISIIISNG-- MET_MUSPF MET_MUSPF VLLGNESCTLTLSESTT-------------NMLKCTVGPAVNE----HFNISIIIANG-- MET_FELCA MET_FELCA VFLGNESCTLTLSESTT-------------NMLKCTVGPAVNE----HFNISIIISNG-- MET_NEONE MET_NEONE VFLGNESCTLTLSESTT-------------NMLKCTVGPAVNE----HFNISIIISNG-- MET_MUNMU MET_MUNMU VLIGNESCTLTLSESTT-------------NMLKCTVGPAMNE----HFNMSIVISNS-- MET_SHEEP MET_SHEEP VLLGNESCTLTLSESTT-------------NMLKCTVGPATNE----HFNMSIVISNS-- MET_BOVIN MET_BOVIN VLLGNESCTLTLTESTT-------------NMLKCTVGPAMNE----HFNMSIVISNS-- A4D7S8_MACEU A4D7S8_MACEU ------------------------------------------------------------ MET_LOXAF MET_LOXAF VLIGNDSCTLTLSESTT-------------NTLKCTVGPAMNK----HFNLSIIISNG-- MET_RABIT MET_RABIT VLLGNESCALNLSESTT-------------NTLKCTVGATTHE----HFNMSITVSNS-- MET_PIG MET_PIG VLLGNESCTLTLSESTT-------------NTLKCTVGPAMNE----HFNMSIVISNG-- MET_EULMM MET_EULMM VLLGNESCTLTLSESTT-------------NMLKCTVGPAMNE----HFNMSIIISHG-- MET_MICMU MET_MICMU VLLGNESCTLTLSESTT-------------NMLKCTVGPAMSE----HFNMSIVISHG-- MET_OTOGA MET_OTOGA VLLGNESCTLTLSESTT-------------NTLKCTVGPAMNE----HFNMSIVISNG-- MET_HORSE MET_HORSE VLLGNESCTLTLSESTS-------------NTLKCTVGPAMNE----RFNISITVSNS-- MET_CERAE MET_CERAE VLLGNESCTLTLSESTM-------------NTLKCTVGPAMNK----HFNMSIIISND-- MET_PAPAN MET_PAPAN VLLGNESCTLTLSESTM-------------NILKCTVGPAMNK----HFNMSIIISNG-- MET_COLGU MET_COLGU VLLGNESCTLTLSESTM-------------NTLKCTVGPAMNK----HFNMSIIISNG-- MET_HYLLE MET_HYLLE VLLGNESCTLTLSESTM-------------NTLKCTVGPAMNK----HFNMSITISNG-- MET_GORGO MET_GORGO VLLGNESCTLTLSESTM-------------NTLKCTVGPAMNK----HFNMSIIISNG-- MET_PANTR MET_PANTR VLLGNESCTLTLSESTM-------------NTLKCTVGPAMNK----HFNMSIIISNG-- MET_PONAB MET_PONAB VLLGNESCTLTLSESTM-------------NILKCTVGPAMNK----HFNMSIIISNG-- B4DLF5_HUMAN B4DLF5_HUMAN VLLGNESCTLTLSESTM-------------NTLKCTVGPAMNK----HFNMSIIISNG-- A1L467_HUMAN A1L467_HUMAN VLLGNESCTLTLSESTM-------------NTLKCTVGPAMNK----HFNMSIIISNG-- MET_HUMAN MET_HUMAN VLLGNESCTLTLSESTM-------------NTLKCTVGPAMNK----HFNMSIIISNG-- Q59EB3_HUMAN Q59EB3_HUMAN ------------------------------------------------------------ MET_CALJA MET_CALJA VLLGNESCTLTLSESTM-------------NTLKCTVGPAMNE----RFNMSIIISNA-- MET_CALMO MET_CALMO VLLGNESCTLTSSESTM-------------NTLKCTIGPAMNE----HFNMSIIISNS-- MET_SAIBB MET_SAIBB VLLGNESCTLTLSESTM-------------NTLKCTVGPAMNE----HFNMSIIISNA-- MET_AOTNA MET_AOTNA VLLGNESCTLTLSESTM-------------NTLKCTVGPAMNE----HFNMSIIISNS-- MET_ATEGE MET_ATEGE VLLGNESCTLTLSESTM-------------NTLKCTVGPAMNE----HFNMSIIISNT-- Q4RS82_TETNG Q4RS82_TETNG ------------------------------------------------------------ Q64GK4_DANRE Q64GK4_DANRE VVVAGTKCKLERKDSNN-------------NRLVCGLDYVNWS----SLDSVITVRSG-- Q08757_CHICK Q08757_CHICK VAVGGRSCTVLLDESESYRPLPTFRRKDFVDVLVCVLEPGEPAVAAGPADVVLNVTESAG B2RUR6_MOUSE B2RUR6_MOUSE ITVGQSPCRLLPKDSSS--PRPG-SLKEFIQELECELEPLVTQ-AVGTTNISLVITNMPA RON_MOUSE RON_MOUSE ITVGQSPCRLLPKDSSS--PRPG-SLKEFIQELECELEPLVTQ-AVGTTNISLVITNMPA Q6DTW4_CANFA Q6DTW4_CANFA VTVGQSPCRLLPKDSSN--LSPV-PQKDFVEELECELQPSGKQ-PAGPANVSLTVTNVPP RON_HUMAN RON_HUMAN VTVGQSPCRPLPKDSSK--LRPV-PRKDFVEEFECELEPLGTQ-AVGPTNVSLTVTNMPP MATCH CONSENSUS V??G???C?L????S???????????????N?L?CT?????????????N?S????????

P70003_XENLA P70003_XENLA GTPYYIKGTV-SAEGFTFVE----------PAITSVEPNFGPLAGGTRLTLKGQNLTAGE P79950_XENLA P79950_XENLA GTPYYIKGTV-SAEGFTFVE----------PAITSVEPNFGPLAGGTRLTLKGQNLTAGE Q4SR43_TETNG Q4SR43_TETNG EGRYSIDGKA-EMSGFTFVYDNDSVKSLQIPNITEIRPNYGPRVGGTLITVTGLHLDAGR Q9W650_XENLA Q9W650_XENLA ------KQVV-NFTTFSYVN----------PIITSIRPSYGPRAGRTLLTIKGHYLDSGK A0M8T9_CHICK A0M8T9_CHICK ------HGKT-LFNTFSYVN----------PIITSISPTYGPKSGGTLLTIAGKYLNSGK Q90975_CHICK Q90975_CHICK ------HGKT-LFNTFSYVN----------PIITSISPTYGPKSGGTLLTIAGKYLNSGK MET_ORNAN MET_ORNAN ------QGGR-RSKTFSYVD----------PKITSISPRYGPIAGGTLLTLTGKYLNCGS A4FUV6_MOUSE A4FUV6_MOUSE ------RETT-QYSAFSYVD----------PVITSISPRYGPQAGGTLLTLTGKYLNSGN MET_MOUSE MET_MOUSE ------RETT-QYSAFSYVD----------PVITSISPRYGPQAGGTLLTLTGKYLNSGN A4FUV7_MOUSE A4FUV7_MOUSE ------RETT-QYSAFSYVD----------PVITSISPRYGPQAGGTLLTLTGKYLNSGN MET_RAT MET_RAT ------RETT-QYSAFSYVD----------PVITSISPRYGPHAGGTLLTLTGKYLNSGN Q2IBC7_RAT Q2IBC7_RAT ------RETT-QYSAFSYVD----------PVITSISPRYGPHAGGTLLTLTGKYLNSGN MET_RHIFE MET_RHIFE ------RGTA-QYTAFSYVD----------PIITSVSPSYGPKTGGTLLTLTGKYLNSGN MET_ATEAB MET_ATEAB ------RGTV-QYSTFSYVD----------PIITSISPTYGPKTGGTLLTLTGKYLDSGN MET_ECHTE MET_ECHTE ------RGTAPQYRTFSYVD----------PEITSISPSYGPKAGGTLVTLTGKYLNSGN Q2QLD2_CARPS Q2QLD2_CARPS ------RGTA-RYSTFSYVD----------PIITSISPSYGPKTGGTLLTLTGKYLNSGN Q07E11_CAVPO Q07E11_CAVPO ------RGTA--HSTFSYVD----------PVITSISPNYGPKAGGTLLTLTGKYLNSGN MET_DASNO MET_DASNO ------RRTV-HYNAFSYVD----------PIITSIFPKYGPKAGGTLLTLTGKYLNSGN MET_CANFA MET_CANFA ------RGTA-QYSTFSYVD----------PIITSISPSYGPKNGGTLLTLTGKYLNSGN MET_MUSPF MET_MUSPF ------RGTA-QYSKFSYVD----------PIITSISPSYGPKTGGTLLTLNGKYLNSGN MET_FELCA MET_FELCA ------RGTA-QYSTFSYVD----------PVITSIFPSYGPKTGGTLLTLTGKYLNSGN MET_NEONE MET_NEONE ------RGTA-QYSTFSYVD----------PVITSIFPSYGPKTGGTLLTLTGKYLNSGN MET_MUNMU MET_MUNMU ------RGSV-QYSTFSYVD----------PIITSISPNYGPKTGGTLLTLTGKHLNSGN MET_SHEEP MET_SHEEP ------RGSV-QYSMFSYVD----------PIITSISPNYGPKTGGTLLTLTGKHLNSGN MET_BOVIN MET_BOVIN ------RGSV-EYSAFSYVD----------PIITSISPNYGPKTGGTLLTLTGKHLNSGN A4D7S8_MACEU A4D7S8_MACEU ------------------------------------------------------------ MET_LOXAF MET_LOXAF ------RGTA-RYRTFSYVE----------PVITSISPSYGPKAGGTLVTLTGKYLNSGN MET_RABIT MET_RABIT ------RGRT-QYSTFSYVA----------PVITSISPSYGPKAGGTLLTLTGKYLDSGN MET_PIG MET_PIG ------RGTT-QYRTFSYVD----------PVITNISPSFGPKTGGTLLTLTGMHLNSGN MET_EULMM MET_EULMM ------RGTA-QYSTFSYVD----------PVITSISPSYGPKAGGTLLTLTGKYLNSGN MET_MICMU MET_MICMU ------RGMT-QYSTFSYVD----------PVITSISPSYGPKAGGTLLTLTGKYLNSGN MET_OTOGA MET_OTOGA ------RETT-QYSTFSYVD----------PVITSISPSYGPKAGGTLLTLIGKYLNSGN MET_HORSE MET_HORSE ------RGTA-RYSTFSYVD----------PIITSISPSYGPKTGGTLLTLTGKYLNSGN MET_CERAE MET_CERAE ------HGTT-QYSTFSYVD----------PIITSISPKYGPMAGGTLLTLTGNYLNSGN MET_PAPAN MET_PAPAN ------HGTT-QYSTFSYVD----------PIITSISPKYGPMAGGTLLTLTGNYLNSGN MET_COLGU MET_COLGU ------HGTT-QYSTFSYVD----------PIITSISPKYGPMAGGTLLTLTGNYLNSGN MET_HYLLE MET_HYLLE ------HGTT-QYSTFSYVD----------PVITSISPKYGPMAGGTLLTLTGNYLNSGN MET_GORGO MET_GORGO ------HGTT-QYSTFSYVD----------PVITSISPKYGPMAGGTLLTLTGNYLNSGN MET_PANTR MET_PANTR ------HGTT-QYSTFSYVD----------PVITSISPKYGPMAGGTLLTLTGNYLNSGN MET_PONAB MET_PONAB ------HGTT-QYSTFSYVD----------PVITGISPKYGPMAGGTLLTLTGNYLNSGN B4DLF5_HUMAN B4DLF5_HUMAN ------HGTT-QYSTFSYVD----------PVITSISPKYGPMAGGTLLTLTGNYLNSGN A1L467_HUMAN A1L467_HUMAN ------HGTT-QYSTFSYVD----------PVITSISPKYGPMAGGTLLTLTGNYLNSGN MET_HUMAN MET_HUMAN ------HGTT-QYSTFSYVD----------PVITSISPKYGPMAGGTLLTLTGNYLNSGN Q59EB3_HUMAN Q59EB3_HUMAN ------------------------------------------------------YLNSGN MET_CALJA MET_CALJA ------HGTT-QYSTFSYVD----------PIITSISPRYGPMSGGTLLTLTGNYLNSGN MET_CALMO MET_CALMO ------HGTT-QYSTFSYVD----------PIITSISPRYGPMSGGTLLTLTGNYLNSGN MET_SAIBB MET_SAIBB ------HGTT-QYSTFSYVD----------PIITSISPRYGPMSGGTLLTLTGNYLNSGN MET_AOTNA MET_AOTNA ------HGTT-QYSTFSYVD----------PIITSISPRYGPMSGGTLLTLTGNYLNSGN MET_ATEGE MET_ATEGE ------HGTT-QYSTFSYVD----------PIITSISPRYGPMSGGTLLTLTGNYLNSGN Q4RS82_TETNG Q4RS82_TETNG -------GTS-------------------------------------------------- Q64GK4_DANRE Q64GK4_DANRE ------KEQA-QKDGFSFVN----------PVIIEIFPEFGPQSGGTMLTISGSFLDSGN Q08757_CHICK Q08757_CHICK TSRFRVQGSS-TLSGFVFVE----------PHISTLHPSFGPQGGGTLMSLYGTHLSAGS B2RUR6_MOUSE B2RUR6_MOUSE GKHFRVEGIS-VQEGFSFVE----------PVLTSIKPDFGPRAGGTYLTLEGQSLSVGT RON_MOUSE RON_MOUSE GKHFRVEGIS-VQEGFSFVE----------PVLTSIKPDFGPRAGGTYLTLEGQSLSVGT Q6DTW4_CANFA Q6DTW4_CANFA GKHFRVDGTS-MLQGFSFME----------PVLTAVKPHFGPRAGGTRLTLEGKGLSLGT RON_HUMAN RON_HUMAN GKHFRVDGTS-VLRGFSFME----------PVLIAVQPLFGPRAGGTCLTLEGQSLSVGT MATCH CONSENSUS ???????G???????FS?V???????????P?ITSI?P??GP??GGTLLTL?G??L?SG?

P70003_XENLA P70003_XENLA TQRVFIDGAECKTINGSDCPA-----EVLCCVSPKSLSLGPLNVFALLDGAQIPSPEQFQ P79950_XENLA P79950_XENLA TQRVFIDGAECKTINGSDCPA-----EVLCCVSPKSLSLGPLNVFALLDGAQIPSPEQFQ Q4SR43_TETNG Q4SR43_TETNG TRKVTLNEVPCPIK---RVTQPKGNVSSIICLSQHISEVRDVPLSVFIDKSPIPTTKVFY Q9W650_XENLA Q9W650_XENLA DRKVYIGKEMCNIK---SVSS-----AAIVCLTPGQGTTGTYLVALKIDNANRESSTRFT A0M8T9_CHICK A0M8T9_CHICK SRRIFVGEKPCSLK---STSE-----SSVECYTPAQRIPQEYRVRVGIDGAIRDAKGYFT Q90975_CHICK Q90975_CHICK SRRIFVGEKPCSLK---STSE-----SSVECYTPAQRIPQEYRVRVGIDGAIRDAKGYFT MET_ORNAN MET_ORNAN SRHISIGGKTCTLR---SVSE-----HVLECYTPSQTVPTLYAVKMKIDLANREAG-TFI A4FUV6_MOUSE A4FUV6_MOUSE SRHISIGGKTCTLK---SVSD-----SILECYTPAQTTSDEFPVKLKIDLANRETS-SFS MET_MOUSE MET_MOUSE SRHISIGGKTCTLK---SVSD-----SILECYTPAQTTSDEFPVKLKIDLANRETS-SFS A4FUV7_MOUSE A4FUV7_MOUSE SRHISIGGKTCTLK---SVSD-----SILECYTPAQTTSDEFPVKLKIDLANRETS-SFS MET_RAT MET_RAT SRHISIGGKTCTLK---SVSD-----SILECYTPGHTVSAEFPVKLKIDLADRVTS-SFS Q2IBC7_RAT Q2IBC7_RAT SRHISIGGKTCTLK---SVSD-----SILECYTPGHTVSAEFPVKLKIDLADRVTS-SFS MET_RHIFE MET_RHIFE SRHISIGGKTCSLK---SVSE-----SVLECYTPAQTTTTEFPIKLKIDLANRETN-SFN MET_ATEAB MET_ATEAB SRHISIGGKTCTLK---SVSN-----SILECYTPPQTTSTEFPVKLKIDLANRNTY-SFS MET_ECHTE MET_ECHTE SRHISIGGKTCTLK---SVSD-----SVLECYTPAQSISADFPVKLKIDLANREAY-SFS Q2QLD2_CARPS Q2QLD2_CARPS SRHISIGGKTCALK---SVSD-----SILECYTPAQTTPTEFPIKLKIDLANRETD-SFS Q07E11_CAVPO Q07E11_CAVPO SRHISIGGKTCTLK---SVSS-----SILECYTPAQTISAEFPIKLKIDLANRETG-SFH MET_DASNO MET_DASNO SRHISIGGKTCTLK---SVSN-----SILECYTPAQIISTEFPIKLKIDLANREAS-SFS MET_CANFA MET_CANFA SRHISMGGKTCTLK---SVSD-----SILECYTPAQATATEFPIKLKIDLANREMN-SFS MET_MUSPF MET_MUSPF SRHISIGGETCTLK---SVSD-----SILECYTPAQTTPTEFPIKLKIDLANREMN-SFS MET_FELCA MET_FELCA SRHISIGGKTCTLK---SVSD-----SILECYTPAQTIPTEFPIKLKIDLANREMN-SFS MET_NEONE MET_NEONE SRHISIGGKTCTLK---SVSD-----SILECYTPAQTIPTEFPIKLKIDLANREMN-SFS MET_MUNMU MET_MUNMU SRHISIGGKTCTLK---SVSH-----SILECYTPAQSTPSEFSIKLKIDLANREVN-SFI MET_SHEEP MET_SHEEP SRHISIGGKTCTLK---SVSY-----SILECYTPAQSAPTEFSVKLKIDLANREVN-SFI MET_BOVIN MET_BOVIN SRHISIGGKTCTLK---SVSH-----SILECYTPAQSAPTEFSVKLKIDLANREVN-SFI A4D7S8_MACEU A4D7S8_MACEU ------------------------------------------------------------ MET_LOXAF MET_LOXAF SRHISIGGKTCTLK---SVSD-----SVLECYTPAQSISTDFPVKLKIDLANREAY-SFS MET_RABIT MET_RABIT SRHISIGGKTCTLK---SMSN-----SILECYTPAQTISTEFPVKLEIDLASRETS-SFS MET_PIG MET_PIG SRHISIGGKTCTLK---SVSD-----SILECYTPAQTTPTEFPIKLKIDLANREIN-SFT MET_EULMM MET_EULMM SRHISIGGKTCTLK---SVSN-----SILECYTPAQIISTEFPVKLKIDLANRETS-SFS MET_MICMU MET_MICMU SRHISIGGKTCTLK---SVSN-----SILECYTPAQIISTEFPVKLKIDLANRETS-SFS MET_OTOGA MET_OTOGA SRHISIGGKTCTLK---SVSN-----SILECYTPAQIISTEFPVKLKIDLAIREAS-SFS MET_HORSE MET_HORSE SRHISIGGKTCTLK---SVSD-----SILECYTPAQTTPTEFPVKLKIDLANREMN-SFS MET_CERAE MET_CERAE SRHISIGGKTCTLK---SVSN-----SVLECYTPAQTISTEFAVKLKIDLANRETS-IFS MET_PAPAN MET_PAPAN SRHISIGGKTCTLK---SVSN-----SILECYTPAQTISTEFAVKLKIDLANRETS-IFS MET_COLGU MET_COLGU SRHISIGGKTCTLK---SVSN-----SILECYTPAQTISTEFAVKLKIDLANRETS-IFS MET_HYLLE MET_HYLLE SRHISIGGKTCTLK---SVSN-----SILECYTPAQTISTEFAVKLKIDLANRETN-IFS MET_GORGO MET_GORGO SRHISIGGKTCTLK---SVSN-----SILECYTPAQTISTEFAVKLRIDLANRETS-IFS MET_PANTR MET_PANTR SRHISIGGKTCTLK---SVSN-----SILECYTPAQTISTEFAVKLKIDLANRETS-IFS MET_PONAB MET_PONAB SRHISIGGKTCTLK---SVSN-----SILECYTPAQTISTEFAVKLKIDLANRETS-IFS B4DLF5_HUMAN B4DLF5_HUMAN SRHISIGGKTCTLK---SVSN-----SILECYTPAQTISTEFAVKLKIDLANRETS-IFS A1L467_HUMAN A1L467_HUMAN SRHISIGGKTCTLK---SVSN-----SILECYTPAQTISTEFAVKLKIDLANRETS-IFS MET_HUMAN MET_HUMAN SRHISIGGKTCTLK---SVSN-----SILECYTPAQTISTEFAVKLKIDLANRETS-IFS Q59EB3_HUMAN Q59EB3_HUMAN SRHISIGGKTCTLK---SVSN-----SILECYTPAQTISTEFAVKLKIDLANRETS-IFS MET_CALJA MET_CALJA SRHISIGGKTCTLK---SVSN-----SILECYTPAQSISTEFPVKLKIDLANRETS-IFS MET_CALMO MET_CALMO SRHISIGGKTCTLK---SVSN-----SILECYTPAQTISTEFPVKLKIDLANRETS-IFS MET_SAIBB MET_SAIBB SRHISIGGKTCTLK---SVSN-----SILECYTPAQTISTEFPVKLKIDLANRETS-IFS MET_AOTNA MET_AOTNA SRHISIGGKTCTLK---SVSN-----SILECYTPAQTISTEFPVKLKIDLANRETS-IFS MET_ATEGE MET_ATEGE SRHISIGGKTCTLK---SVSN-----SILECYTPAQTISTEFPVKLKIDLANRETS-IFS Q4RS82_TETNG Q4RS82_TETNG ------------------------------------------------------------ Q64GK4_DANRE Q64GK4_DANRE VQTVTVGNATCVLQ---SVSA-----TMLTCRTPPQPSPSQHKVQLHIDGVIFEAPVSYT Q08757_CHICK Q08757_CHICK SWRVTINGSECLLDGQPSEGD-----GEIRCTAPAATSLGAAPVALWIDGEEFLAPLPFE B2RUR6_MOUSE B2RUR6_MOUSE SRAVLVNGTQCRLE---QVNE-----EQILCVTPPGAGTARVPLHLQIGGAEVPGSWTFH RON_MOUSE RON_MOUSE SRAVLVNGTQCRLE---QVNE-----EQILCVTPPGAGTARVPLHLQIGGAEVPGSWTFH Q6DTW4_CANFA Q6DTW4_CANFA SQTVLVNGTECPLK---QVSE-----QQLLCTTPPGAATAIVPIHLQVGGAVVPGSWNFH RON_HUMAN RON_HUMAN SRAVLVNGTECLLA---RVSE-----GQLLCATPPGATVASVPLSLQVGGAQVPGSWTFQ MATCH CONSENSUS SR???IGG??C?LK???SVS????????L?C?TP???????????L?ID?A?R?????F?

P70003_XENLA P70003_XENLA YKPDPSISDIRPNCS-LASGTPLTIQGSNLDSASSISVILNNGE-----KAIRSACKGTF P79950_XENLA P79950_XENLA YKPDPSISDIRPNCS-LASGTPLTIQGSNLDSASSISVILNNGE-----KAIRSACKGTF Q4SR43_TETNG Q4SR43_TETNG YKENPKITAVLPDCSF-DRGSKIVIEGENLDSVY--RTIVRFKPNESHLKPVTRECVGNS Q9W650_XENLA Q9W650_XENLA YMEDPSVSSIKPVKSFLSGGSSITAYGKNLNAVASPLMVIHLSKLE---VSYNMSCIHRS A0M8T9_CHICK A0M8T9_CHICK YREDPVVLKIHPAKSFLSGGSTITAQGINLNSVCFPRMVITVPKLG---MNFSVACSHRS Q90975_CHICK Q90975_CHICK YREDPVVLKIHPAKSFLSGGSTITAQGINLNSVCFPRMVITVPKLG---MNFSVACSHRS MET_ORNAN MET_ORNAN YKEDPVIHEIHPTKSFLSGGSTITGFGKNLNGSSAPKMIIQVAEVG---RNFTVACQSRS A4FUV6_MOUSE A4FUV6_MOUSE YREDPVVYEIHPTKSFISGGSTITGIGKTLNSVSLPKLVIDVHEVG---VNYTVACQHRS MET_MOUSE MET_MOUSE YREDPVVYEIHPTKSFISGGSTITGIGKTLNSVSLPKLVIDVHEVG---VNYTVACQHRS A4FUV7_MOUSE A4FUV7_MOUSE YREDPVVYEIHPTKSFISGGSTITGIGKTLNSVSLPKLVIDVHEVG---VNYTVACQHRS MET_RAT MET_RAT YREDPVVSEIHPTKSFISGGSTITGIGKNLNSVSTPKLVIEVHDVG---VNYTVACQHRS Q2IBC7_RAT Q2IBC7_RAT YREDPVVSEIHPTKSFISGGSTITGIGKNLNSVSTPKLVIEVHDVG---VNYTVACQHRS MET_RHIFE MET_RHIFE YREDPIVDEIHPTKSFISGGSTITGVGKNLNSVSGLRMVISVREAG---RNFTVACQHRS MET_ATEAB MET_ATEAB YQEDPIIYKIHPIKSFISGGSTITGVGKNLNSVSVLRMVINVHEAG---RNFTVACQHRS MET_ECHTE MET_ECHTE YQENPLVVEIHPTKSFVSGGSTITVVGKNLNSVSVPRMIINVHEVE---MNFTVACQQRS Q2QLD2_CARPS Q2QLD2_CARPS YQEDPIVYEIHPTKSFISGGSTITGVGKNLNSVSVLRMIINVHEAG---RNFTVACRRRS Q07E11_CAVPO Q07E11_CAVPO YQDDPIVYEIHPTKSFISGGSTITGIGKNLNSVSVPRLVINVHEAG---KNYTVACQHRS MET_DASNO MET_DASNO YREDPIVYEIHPTKSFLSGGSTITGVGKNLNSVSVTRMVINVHEAR---KNFTVACQHRS MET_CANFA MET_CANFA YQEDPIVYAIHPTKSFISGGSTITAVGKNLNSVSVLRMVIDVHETR---RNFTVACQHRS MET_MUSPF MET_MUSPF YQEDPIVYAIHPTKSFISGGSTITAIGKNLHSVSVLRMGINVHEAR---RNFTVACQHRS MET_FELCA MET_FELCA YQEDPIVYAIHPTKSFISGGSTITAVGKNLNSVSVLRMVISVHETR---RNFTVACHHRS MET_NEONE MET_NEONE YQEDPIVYAIHPTKSFISGGSTITAVGKNLNSVSVLRMVISVHETR---RNFTVACHHRS MET_MUNMU MET_MUNMU YREDPIVYEIHPTKSFVSGGSTITGVGKNLNSVSILRMVINVHEAG---RNFTVACQHRS MET_SHEEP MET_SHEEP YREDPIVYEIHPTKSFISGGSTITGVGKNLNSVSIIRMVINVHEAG---KNFTVACQHRS MET_BOVIN MET_BOVIN YREDPIVYEIHPTKSFISGGSTITGVGKNLNSVSVLRMVINVHEAG---RNFTVACQHRS A4D7S8_MACEU A4D7S8_MACEU ------------------------------------------------------------ MET_LOXAF MET_LOXAF YQEDPTVYEIHPNKSFISGGSTITGIGKNLNSVSVPRMVINVQEAG---RNFTVACQHRS MET_RABIT MET_RABIT YREDPIVDEFYPTKSFISGGSTITGVGKNLDSVSVPRMVISVHEAG---SNFTVACQHRS MET_PIG MET_PIG YREDPIVYEIHPTKSFISGGSTITGVGRNLNSVSVLRMVINVHEAE---RNFTVACQHRS MET_EULMM MET_EULMM YREDPIVHEIHPTKSFVSGGSTITGVGKNLNSVSVPRMVINVQEAG---RNFTVACQHRS MET_MICMU MET_MICMU YQEDPVVYEIHPTKSFVSGGSTITGVGKNLNSVSVPRMVINVQEAG---RNFTVACQHRS MET_OTOGA MET_OTOGA YQEDPIVYEIHPMKSFVSGGSTITGVGKNLNSVSVPRMVIHVREAG---RDFTVACQHRS MET_HORSE MET_HORSE YREDPIVYEIHPTKSFISGGSTITGVGKNLNSVSVLRMVINVREAG---RNFTVACQHRS MET_CERAE MET_CERAE YREDPIVYEIHPTKSFISGGSTITGVGKNLHSVSIPRMVINVHEAG---RNFTVACQHRS MET_PAPAN MET_PAPAN YREDPIVYEIHPTKSFISGGSTITGVGKNLHSVSVPRMVINVHEAG---RNFTVACQHRS MET_COLGU MET_COLGU YREDPIVYEIHPTKSFISGGSTITGVGKNLHSVSVPRMVINVHEAG---RNFTVACQHRS MET_HYLLE MET_HYLLE YREDPIVYEIHPTKSFISGGSTITGVGKNLNSVSVPRMVINVHEAG---RNFTVACQHRS MET_GORGO MET_GORGO YREDPIVYEIHPTKSFISGGSTITGVGKNLNSVSVPRMVINVHEAG---RNFTVACQHRS MET_PANTR MET_PANTR YREDPIVYEIHPTKSFISGGSTITGVGKNLNSVSVPRMVINVHEAG---RNFTVACQHRS MET_PONAB MET_PONAB YREDPIVYEIHPTKSFISGGSTITGVGKNLNSVSVPRMVINVHEAG---RNFTVACQHRS B4DLF5_HUMAN B4DLF5_HUMAN YREDPIVYEIHPTKSFISGGSTITGVGKNLNSVSVPRMVINVHEAG---RNFTVACQHRS A1L467_HUMAN A1L467_HUMAN YREDPIVYEIHPTKSFISGGSTITGVGKNLNSVSVPRMVINVHEAG---RNFTVACQHRS MET_HUMAN MET_HUMAN YREDPIVYE