Alignment of the gene Family HBG007506 of HOVERGEN

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Isoforms are ON
Q4SSS2_TETNG Q4SSS2_TETNG ------------------------------------------------------------ Q2L9D2_MOUSE Q2L9D2_MOUSE ------------------------------------------------------------ Q3U195_MOUSE Q3U195_MOUSE ------------------------------------------------------------ FGD2_MOUSE FGD2_MOUSE ------------------------------------------------------------ Q0V7M5_BOVIN Q0V7M5_BOVIN ------------------------------------------------------------ A8K304_HUMAN A8K304_HUMAN ------------------------------------------------------------ FGD2_HUMAN FGD2_HUMAN ------------------------------------------------------------ FGD4_MOUSE FGD4_MOUSE ------------------------------------------------------------ FGD4_RAT FGD4_RAT ------------------------------------------------------------ Q49A55_HUMAN Q49A55_HUMAN ------------------------------------------------------------ B7Z8F9_HUMAN B7Z8F9_HUMAN ------------------------------------------------------------ B7Z493_HUMAN B7Z493_HUMAN ------------------------------------------------------------ FGD4_HUMAN FGD4_HUMAN ------------------------------------------------------------ Q4SKH1_TETNG Q4SKH1_TETNG ------------------------------------------------------------ Q1L9G3_DANRE Q1L9G3_DANRE ------------------------------------------------------------ B0V1Q7_DANRE B0V1Q7_DANRE ------------------------------------------------------------ Q2YDU5_RAT Q2YDU5_RAT ------------------------------------------------------------ FGD1_MOUSE FGD1_MOUSE HGHRVPGGPGPSDPERSAANTPGAAPLACADSDPGALEPGLPVSRGSGTALGGPLDPQFV Q3UG32_MOUSE Q3UG32_MOUSE HGHRVPGGPGPSDPERSAANTPGAAPLACADSDPGALEPGLPVSRGSGTALGGPLDPQFV A2ALP5_MOUSE A2ALP5_MOUSE ------------------------------------------------------------ Q921L2_MOUSE Q921L2_MOUSE HGHRVPGGPGPSDPERSAANTPGAAPLACADSDPGALEPGLPVSRGSGTALGGPLDPQFV A5D7I5_BOVIN A5D7I5_BOVIN HGHRAPGGAGPSEPEHPTANSPGAASPAYADSDPGASEPGLPVPRGSGSALGSLLDPQFA B4DS99_HUMAN B4DS99_HUMAN ------------------------------------------------------------ FGD1_HUMAN FGD1_HUMAN HGHRAPGGAGPSEPEHPATNPPGAAPPACADSDPGASEPGLLARRGSGSALGGPLDPQFV FGD3_MOUSE FGD3_MOUSE ------------------------------------------------------------ Q3TNB8_MOUSE Q3TNB8_MOUSE ------------------------------------------------------------ Q3MHR4_BOVIN Q3MHR4_BOVIN ------------------------------------------------------------ Q58CS5_BOVIN Q58CS5_BOVIN ------------------------------------------------------------ Q0V8A6_BOVIN Q0V8A6_BOVIN ------------------------------------------------------------ Q9NXY1_HUMAN Q9NXY1_HUMAN ------------------------------------------------------------ FGD3_PONAB FGD3_PONAB ------------------------------------------------------------ A8K9G1_HUMAN A8K9G1_HUMAN ------------------------------------------------------------ FGD3_HUMAN FGD3_HUMAN ------------------------------------------------------------ Q4RJT9_TETNG Q4RJT9_TETNG ------------------------------------------------------------ O93504_DANRE O93504_DANRE ------------------------------------------------------------ Q4V9K2_DANRE Q4V9K2_DANRE ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

Q4SSS2_TETNG Q4SSS2_TETNG ------------------------------------------------------------ Q2L9D2_MOUSE Q2L9D2_MOUSE ------------------------------------------------------------ Q3U195_MOUSE Q3U195_MOUSE ------------------------------------------------------------ FGD2_MOUSE FGD2_MOUSE ------------------------------------------------------------ Q0V7M5_BOVIN Q0V7M5_BOVIN ------------------------------------------------------------ A8K304_HUMAN A8K304_HUMAN ------------------------------------------------------------ FGD2_HUMAN FGD2_HUMAN ------------------------------------------------------------ FGD4_MOUSE FGD4_MOUSE ------------------------------------------------------------ FGD4_RAT FGD4_RAT ------------------------------------------------------------ Q49A55_HUMAN Q49A55_HUMAN ------------------------------------------------------------ B7Z8F9_HUMAN B7Z8F9_HUMAN ---MNFKRVKPNIFLLNQSRLIISICEIMSTDQGSSTCPKIALVPPCSTSSTTTLVGENV B7Z493_HUMAN B7Z493_HUMAN ------------------------------MGGCSSTCPKIALVPPCSTSSTTTLVGENV FGD4_HUMAN FGD4_HUMAN ------------------------------------------------------------ Q4SKH1_TETNG Q4SKH1_TETNG ------------------------------------------------------------ Q1L9G3_DANRE Q1L9G3_DANRE ------------------------------------------------------------ B0V1Q7_DANRE B0V1Q7_DANRE ------------------------------------------------------------ Q2YDU5_RAT Q2YDU5_RAT ------------------------------------------------------------ FGD1_MOUSE FGD1_MOUSE GPSDASLGAPPSSRVLPCGPSPQHHRALRFSYHLEGSQPRPGLHQGNRILVKSLSLDPGQ Q3UG32_MOUSE Q3UG32_MOUSE GPSDASLGAPPSSRVLPCGPSPQHHRALRFSYHLEGSQPRPGLHQGNRILVKSLSLDPGQ A2ALP5_MOUSE A2ALP5_MOUSE ------------------------------------------------------------ Q921L2_MOUSE Q921L2_MOUSE GPSDASLGAPPSSRVLPCGPSPQHHRALRFSYHLEGSQPRPGLHQGNRILVKSLSLDPGQ A5D7I5_BOVIN A5D7I5_BOVIN GPSDTSLGVAPGPRVLPCGPSPQHHRALRFSYHLEGSQPRPGMHQGNRILVKSLSLDPGQ B4DS99_HUMAN B4DS99_HUMAN ------------------------------------------------------------ FGD1_HUMAN FGD1_HUMAN GPSDTSLGAAPGHRVLPCGPSPQHHRALRFSYHLEGSQPRPGLHQGNRILVKSLSLDPGQ FGD3_MOUSE FGD3_MOUSE ------------------------------------------------------------ Q3TNB8_MOUSE Q3TNB8_MOUSE ------------------------------------------------------------ Q3MHR4_BOVIN Q3MHR4_BOVIN ------------------------------------------------------------ Q58CS5_BOVIN Q58CS5_BOVIN ------------------------------------------------------------ Q0V8A6_BOVIN Q0V8A6_BOVIN ------------------------------------------------------------ Q9NXY1_HUMAN Q9NXY1_HUMAN --------------------------------------------------------TCWA FGD3_PONAB FGD3_PONAB ------------------------------------------------------------ A8K9G1_HUMAN A8K9G1_HUMAN ------------------------------------------------------------ FGD3_HUMAN FGD3_HUMAN ------------------------------------------------------------ Q4RJT9_TETNG Q4RJT9_TETNG ------------------------------------------------------------ O93504_DANRE O93504_DANRE ------------------------------------------------------------ Q4V9K2_DANRE Q4V9K2_DANRE ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

Q4SSS2_TETNG Q4SSS2_TETNG ------------------------------------------------------------ Q2L9D2_MOUSE Q2L9D2_MOUSE ------------------------------------------------------------ Q3U195_MOUSE Q3U195_MOUSE ------------------------------------------------------------ FGD2_MOUSE FGD2_MOUSE ------------------------------------------------------------ Q0V7M5_BOVIN Q0V7M5_BOVIN ------------------------------------------------------------ A8K304_HUMAN A8K304_HUMAN ------------------------------------------------------------ FGD2_HUMAN FGD2_HUMAN ------------------------------------------------------------ FGD4_MOUSE FGD4_MOUSE -------------------------------------------------------MEESN FGD4_RAT FGD4_RAT -------------------------------------------------------MEESN Q49A55_HUMAN Q49A55_HUMAN ------------------------------------------------------------ B7Z8F9_HUMAN B7Z8F9_HUMAN SEEEAQGINGNRPAKHSAASPKPQVPPKPLHLQNSPSSNIHQTPRHKALPSAKPRMEEIK B7Z493_HUMAN B7Z493_HUMAN SEEEAQGINGNRPAKHSAASPKPQVPPKPLHLQNSPSSNIHQTPRHKALPSAKPRMEEIK FGD4_HUMAN FGD4_HUMAN -------------------------------------------------------MEEIK Q4SKH1_TETNG Q4SKH1_TETNG ------------------------------------------------------------ Q1L9G3_DANRE Q1L9G3_DANRE ------------------------------------------------------------ B0V1Q7_DANRE B0V1Q7_DANRE ------------------------------------------------------------ Q2YDU5_RAT Q2YDU5_RAT ------------------------------------------------MPRVLPPPEPIP FGD1_MOUSE FGD1_MOUSE SLEPHPEGPQRLRSDPGPPTEIPGPRPSPLKRAPGPKPQVPPKPSYLQMPRVLPPPEPIP Q3UG32_MOUSE Q3UG32_MOUSE SLEPHPEGPQRLRSDPGPPTEIPGPRPSPLKRAPGPKPQVPPKPSYLQMPRVLPPPEPIP A2ALP5_MOUSE A2ALP5_MOUSE ------------------------------------------------MPRVLPPPEPIP Q921L2_MOUSE Q921L2_MOUSE SLEPHPEGPQRLRSDPGPPTEIPGPRPSPLKRAPGPKPQVPPKPSYLQMPRVLPPPEPIP A5D7I5_BOVIN A5D7I5_BOVIN GLEPHPEGPQRLRSDPGPPTETPSQRPSPLKRAPGPKPQVPPKPSYLQMPRMPPPPEPIP B4DS99_HUMAN B4DS99_HUMAN ------------------------------------------------------------ FGD1_HUMAN FGD1_HUMAN SLEPHPEGPQRLRSDPGPPTETPSQRPSPLKRAPGPKPQVPPKPSYLQMPRMPPPLEPIP FGD3_MOUSE FGD3_MOUSE ------------------------------------------------------------ Q3TNB8_MOUSE Q3TNB8_MOUSE ------------------------------------------------------------ Q3MHR4_BOVIN Q3MHR4_BOVIN ------------------------------------------------------------ Q58CS5_BOVIN Q58CS5_BOVIN ------------------------------------------------------------ Q0V8A6_BOVIN Q0V8A6_BOVIN ------------------------------------------------------------ Q9NXY1_HUMAN Q9NXY1_HUMAN RKRFSRKPSTVCKLLPANPRPQHGARRLCPPTLSILLRKAGGIRKPLASLHLSPVSSALR FGD3_PONAB FGD3_PONAB ------------------------------------------------------------ A8K9G1_HUMAN A8K9G1_HUMAN ------------------------------------------------------------ FGD3_HUMAN FGD3_HUMAN ------------------------------------------------------------ Q4RJT9_TETNG Q4RJT9_TETNG ----------------------------------------------MDAASGDSSCSQDA O93504_DANRE O93504_DANRE -----------------------------------------------------------M Q4V9K2_DANRE Q4V9K2_DANRE -----------------------------------------------------------M MATCH CONSENSUS ????????????????????????????????????????????????????????????

Q4SSS2_TETNG Q4SSS2_TETNG ------------------------------------------------------------ Q2L9D2_MOUSE Q2L9D2_MOUSE --------------------MERACEKQDSVCNLVAVFENNRTPGEAPGSHSLEDQPHIP Q3U195_MOUSE Q3U195_MOUSE --------------------MERACEKQDSVCNLVAVFENNRTPGEAPGSHSLEDQPHSP FGD2_MOUSE FGD2_MOUSE --------------------MERACEKQDSVCNLVAVFENNRTPGEAPGSHSLEDQPHSP Q0V7M5_BOVIN Q0V7M5_BOVIN -------------------MEGASEETLTSVSSLVTVFENSRMTGAVPRVHGLEAGHQQP A8K304_HUMAN A8K304_HUMAN -------------------MKGASEEKLASVSNLVTVFENSRTPEAAPRGHRLEDVHHRP FGD2_HUMAN FGD2_HUMAN -------------------MKGASEEKLASVSNLVTVFENSRTPEAAPRGQRLEDVHHRP FGD4_MOUSE FGD4_MOUSE PAPTSCTSKGKHSKVSDLISHFEGGSVLSSYIDLQKDSTMNLNIPQTLG-QPGLTSSPPR FGD4_RAT FGD4_RAT PAPTSCASKGKHSKVSDLISHFEGGSVLSSYTDVQKDSTMNLNIPQTPRQH-GLTSTTPQ Q49A55_HUMAN Q49A55_HUMAN ------------------------------------------------------------ B7Z8F9_HUMAN B7Z8F9_HUMAN PASASCVSKEKPSKVSDLISRFEGGSSLSNYSDLKKESAVNLNAPRTPGRH-GLTTTPQQ B7Z493_HUMAN B7Z493_HUMAN PASASCVSKEKPSKVSDLISRFEGGSSLSNYSDLKKESAVNLNAPRTPGRH-GLTTTPQQ FGD4_HUMAN FGD4_HUMAN PASASCVSKEKPSKVSDLISRFEGGSSLSNYSDLKKESAVNLNAPRTPGRH-GLTTTPQQ Q4SKH1_TETNG Q4SKH1_TETNG ------------------------------------------------------------ Q1L9G3_DANRE Q1L9G3_DANRE ------------------------------------------------------------ B0V1Q7_DANRE B0V1Q7_DANRE ------------------------------------------------------------ Q2YDU5_RAT Q2YDU5_RAT PPPSRPLPAD-PRVAKGLAPRAEASTSSAAVSSLIEKFEREPVIVASDRPAPGPCPVPPE FGD1_MOUSE FGD1_MOUSE PPPSRPLPAD-PRVAKGLVPRAEASTSSAAVSSLIEKFEREPVIVASDRPAPGPCPVPPE Q3UG32_MOUSE Q3UG32_MOUSE PPPSRPLPAD-PRVAKGPVPRAEASTSSAAVSSLIEKFEREPVIVASDRPAPGPCPVPPE A2ALP5_MOUSE A2ALP5_MOUSE PPPSRPLPAD-PRVAKGLVPRAEASTSSAAVSSLIEKFEREPVIVASDRPAPGPCPVPPE Q921L2_MOUSE Q921L2_MOUSE PPPSRPLPAD-PRVAKGLVPRAEASTSSAAVSSLIEKFEREPVIVASDRPAPGPCPVPPE A5D7I5_BOVIN A5D7I5_BOVIN PPPSRPLPAD-PRVAKGLASRTEASPSSAAVSSLIEKFEREPVIVASDRPAPGPSPSPTE B4DS99_HUMAN B4DS99_HUMAN ------------------------------------------------------------ FGD1_HUMAN FGD1_HUMAN PPPSRPLPAD-PRVAKGLAPRAEASPSSAAVSSLIEKFEREPVIVASDRPVPGPSPGPPE FGD3_MOUSE FGD3_MOUSE MELGRSSSTP-QEEAISPLGVLGTGPSSSPL-------GKLQALPIGPGAHRGA-----H Q3TNB8_MOUSE Q3TNB8_MOUSE MELGRSPSTP-QEEAISPLGVLGTGPSSSPL-------GKLQALPIGPGAHRGA-----H Q3MHR4_BOVIN Q3MHR4_BOVIN MEPGRGSST--PPAPSATMEEPDAGPNNSSLEQPSTDPGKLPALPVGPGTHHGELASGSP Q58CS5_BOVIN Q58CS5_BOVIN MEPGRGSSTP-P-APSATMEEPDAGPNNSSLEQPSTDPGKLPALPVGPGTHHGELASGSP Q0V8A6_BOVIN Q0V8A6_BOVIN MEPGRGSSTP-P-APSATMEEPDAGPNNSSLEQPSTDPGKLPALPVGPGTHHGELASGSP Q9NXY1_HUMAN Q9NXY1_HUMAN MESGRGSSTP-P-GPIAALGMPDTGPGSSSL-------GKLQALPVGPRAHCGD-----P FGD3_PONAB FGD3_PONAB MESGGGSSTP-P-GPIAALGMPDSGPGSSSL-------GKLQALPVGPRAHCGD-----P A8K9G1_HUMAN A8K9G1_HUMAN MESGRGSSTP-P-GPIAALGMPDTGPGSSSL-------GKLQALPVGPRAHCGD-----P FGD3_HUMAN FGD3_HUMAN MESGRGSSTP-P-GPIAALGMPDTGPGSSSL-------GKLQALPVGPRAHCGD-----P Q4RJT9_TETNG Q4RJT9_TETNG AAKVDGDPSPVEKLALATSDLADDVPDLSRLASVHIDDCAEEEIAHGNGCLDIEPEDGSS O93504_DANRE O93504_DANRE MDSPDILHSD---AQLSLSDRLSCTPAEIS--------GLSDAVQCSKHTQESSEHTPML Q4V9K2_DANRE Q4V9K2_DANRE MDSPDILHSD---AQLSLSDRLSCTPAEIS--------GLSDAVQCSKHTQESSEHTPML MATCH CONSENSUS ????????????????????????????????????????????????????????????

Q4SSS2_TETNG Q4SSS2_TETNG ----------------------------------------------ELEQTGEGEEPKVE Q2L9D2_MOUSE Q2L9D2_MOUSE EHQLSLSPEPWEAPPVKE-------------ALKSEFRPVSRTYLSSLKNKLSSGAWRR- Q3U195_MOUSE Q3U195_MOUSE EHQLSLSPEPWEAPPVKE-------------ALKSEFRPVSRTYLSSLKNKLSSGAWRR- FGD2_MOUSE FGD2_MOUSE EHQLSLSPEPWEAPPVKE-------------ALKSEFRPVSRTYLSSLKNKLSSGAWRR- Q0V7M5_BOVIN Q0V7M5_BOVIN GCRAPTSAGPWEKPTVEE-------------ALESGSRTVSRRYLSSLKNKLSSGAWRK- A8K304_HUMAN A8K304_HUMAN ECRPPESPGPREKTNVGE-------------AVGSEPRTVSRRYLNSLKNKLSSEAWRK- FGD2_HUMAN FGD2_HUMAN ECRPPESPGPREKTNVGE-------------AVGSEPRTVSRRYLNSLKNKLSSEAWRK- FGD4_MOUSE FGD4_MOUSE KFLPQHSPQKQENDPDQTQGQHGCLANGVVAAQNQMECEDEKETTLSPEMAIQTAAASPD FGD4_RAT FGD4_RAT KLPSHKSPQKQEKDSDQNQGQHGCLANGVAAAQSQMECETEKEAALSPETDTQTAAASPD Q49A55_HUMAN Q49A55_HUMAN ------------------------------------------------------------ B7Z8F9_HUMAN B7Z8F9_HUMAN KLLSQHLPQRQGNDTDKTQGAQTCVANGVMAAQNQMECEEEKAATLSSDTSIQASEPLLD B7Z493_HUMAN B7Z493_HUMAN KLLSQHLPQRQGNDTDKTQGAQTCVANGVMAAQNQMECEEEKAATLSSDTSIQASEPLLD FGD4_HUMAN FGD4_HUMAN KLLSQHLPQRQGNDTDKTQGAQTCVANGVMAAQNQMECEEEKAATLSSDTSIQASEPLLD Q4SKH1_TETNG Q4SKH1_TETNG ------------------------------------------------------------ Q1L9G3_DANRE Q1L9G3_DANRE ------------------------------------------------------------ B0V1Q7_DANRE B0V1Q7_DANRE ------------------------------------------------------------ Q2YDU5_RAT Q2YDU5_RAT PAMLPQPPPQPTGSQLPEGEASRCLFLLAPGPRDGEKVPNRDSGIDSISSPSNSEET-C- FGD1_MOUSE FGD1_MOUSE PAMLPQPPPQPTGSQLPEGEASRCLFLLAPGPRDGEKVPNRDSGIDSISSPSNSEET-C- Q3UG32_MOUSE Q3UG32_MOUSE PAMLPQPPPQPTGSQLPEGEASRCLFLPAPGPRDGEKVPNRDSGIDSISSPSNSEET-C- A2ALP5_MOUSE A2ALP5_MOUSE PAMLPQPPPQPTGSQLPEGEASRCLFLLAPGPRDGEKVPNRDSGIDSISSPSNSEET-C- Q921L2_MOUSE Q921L2_MOUSE PAMLPQPPPQPTGSQLPEGEASRCLFLLAPGPRDGEKVPNRDSGIDSISSPSNSEET-C- A5D7I5_BOVIN A5D7I5_BOVIN PAMLPQPPPQPPVPQLPEGEASRCLFLLAPGPRDGEKVPNRDSGIDSISSPSNSEET-C- B4DS99_HUMAN B4DS99_HUMAN --MLPQPTSQPPVPQLPEGEASRCLFLLAPGPRDGEKVPNRDSGIDSISSPSNSEET-C- FGD1_HUMAN FGD1_HUMAN PVMLPQPTSQPPVPQLPEGEASRCLFLLAPGPRDGEKVPNRDSGIDSISSPSNSEET-C- FGD3_MOUSE FGD3_MOUSE SSSAPAGD-----SSTRE-------------PSGAMKIPNRDSGIDSPSSSVASENFPC- Q3TNB8_MOUSE Q3TNB8_MOUSE SSSAPAGD-----SSTRE-------------PSGAMKIPNRDSGIDSPSSSVASENFPC- Q3MHR4_BOVIN Q3MHR4_BOVIN GSQASAGDMSSVGEASSS------------------KIPNRDSGIDSPSCSVVSEHF-C- Q58CS5_BOVIN Q58CS5_BOVIN GSQASAGDMSSVGEASSS------------------KIPNRDSGIDSPSCSVVSEHF-C- Q0V8A6_BOVIN Q0V8A6_BOVIN GSQASAGDMSSVGEASSS------------------KIPNRDSGIDSPSCSVVSEHF-C- Q9NXY1_HUMAN Q9NXY1_HUMAN VSLAAAGDGSPDIGPTGE-------------LSGSLKIPNRDSGIDSPSSSVAGENFPC- FGD3_PONAB FGD3_PONAB GSLAAAGDGSLDTGSTGE-------------LSGSLKIPNRDSGIDSPSSSVAGENFPC- A8K9G1_HUMAN A8K9G1_HUMAN VSLAAAGDGSPDIGPTGE-------------LSGSLKIPNRDSGIDSPSSSVAGENFPC- FGD3_HUMAN FGD3_HUMAN VSLAAAGDGSPDIGPTGE-------------LSGSLKIPNRDSGIDSPSSSVAGENFPC- Q4RJT9_TETNG Q4RJT9_TETNG HNLLDNRDSSDQNG----------------------KIPNRDSGIDSPSCTAEGEVFPN- O93504_DANRE O93504_DANRE QDVPPEADGETSG-----------------------KIPNRDSGIDSPSCGGEGECFPNE Q4V9K2_DANRE Q4V9K2_DANRE QDVPPEADGETSG-----------------------KIPNRDSGIDSPSCGGEGECFPNE MATCH CONSENSUS ??????????????????????????????????????????????S?????????????

Q4SSS2_TETNG Q4SSS2_TETNG E----------------------------------------------------------- Q2L9D2_MOUSE Q2L9D2_MOUSE ----------------SCQPGVSPGP---------------------------------- Q3U195_MOUSE Q3U195_MOUSE ----------------SCQPGVSPGP---------------------------------- FGD2_MOUSE FGD2_MOUSE ----------------SCQPGVSPGP---------------------------------- Q0V7M5_BOVIN Q0V7M5_BOVIN ----------------SYQPRTCPGSG--------------------------------- A8K304_HUMAN A8K304_HUMAN --------------SCQPVTLSRSG----------------------------------- FGD2_HUMAN FGD2_HUMAN -------SCQPVTLSGS------------------------------------------- FGD4_MOUSE FGD4_MOUSE THVLNGERNETITDSASSIANSHDENASDSSCRTPGTDLGLPSKEGEPGMD----AELQE FGD4_RAT FGD4_RAT AHVLNGVRNETTTDSASSVTNSHDENACDSSCRTQGTDLGLPSKEGEPVIE----AELQE Q49A55_HUMAN Q49A55_HUMAN ------------------------------------------------------------ B7Z8F9_HUMAN B7Z8F9_HUMAN THIVNGERDETATAPASPTTDSCDGNASDSSYRTPGIGPVLPLEERGAETE----TKVQE B7Z493_HUMAN B7Z493_HUMAN THIVNGERDETATAPASPTTDSCDGNASDSSYRTPGIGPVLPLEERGAETE----TKVQE FGD4_HUMAN FGD4_HUMAN THIVNGERDETATAPASPTTDSCDGNASDSSYRTPGIGPVLPLEERGAETE----TKVQE Q4SKH1_TETNG Q4SKH1_TETNG ------------------------------------------------------------ Q1L9G3_DANRE Q1L9G3_DANRE ------------------------------------------------------------ B0V1Q7_DANRE B0V1Q7_DANRE ------------------------------------------------------------ Q2YDU5_RAT Q2YDU5_RAT ----------FVSDDGPPSHSLCPGPPALASMPVALADPHRPGSQEVDSDLEEEEEEEEE FGD1_MOUSE FGD1_MOUSE ----------FVSDDGPPIHSLCPGPPALASMPVALADPHRPGSQEVDSDL--EEEEEEE Q3UG32_MOUSE Q3UG32_MOUSE ----------FVSDDGPPIHSLCPGPPALASMPVALADPHRPGSQEVDSDL--EEEEEEE A2ALP5_MOUSE A2ALP5_MOUSE ----------FVSDDGPPIHSLCPGPPALASMPVALADPHRPGSQEVDSDL--EEEEEEE Q921L2_MOUSE Q921L2_MOUSE ----------FVSDDGPPIHSLCPGPPALASMPVALADPHRPGSQEVDSDL--EEEEEEE A5D7I5_BOVIN A5D7I5_BOVIN ----------FISDDGPPSHGLCPGPPALASVPVALADPHRPSSQEVDSDL--EEEDDEE B4DS99_HUMAN B4DS99_HUMAN ----------FVSDDGPPSHSLCPGPPALASVPVALADPHRPGSQEVDSDL-EEEDDEEE FGD1_HUMAN FGD1_HUMAN ----------FVSDDGPPSHSLCPGPPALASVPVALADPHRPGSQEVDSDL-EEEDDEEE FGD3_MOUSE FGD3_MOUSE ----------EESSEGSPSPAILGLPSETA---SDSRVPQDNPQEEEDSGV----G---- Q3TNB8_MOUSE Q3TNB8_MOUSE ----------EESSEGSPSPAILGLPSETA---SDSRVPQDNPQEEEDSGM----G---- Q3MHR4_BOVIN Q3MHR4_BOVIN ----------EDSGEAGPGTIIKGPHPGTA---LGSKSP----QEEADSDA----GEGSS Q58CS5_BOVIN Q58CS5_BOVIN ----------EDSGEAGPGTIIKGPHPGTA---LGSKSP----QEEADSDA----GEGSS Q0V8A6_BOVIN Q0V8A6_BOVIN ----------EDSGEAGPGTIIKGPHPGTA---LGSKSP----QEEADSDA----GEGSS Q9NXY1_HUMAN Q9NXY1_HUMAN ----------EEGLEAGPSPTVLGAHAEMA---LDSQVPKVTPQEEADSDV----G---- FGD3_PONAB FGD3_PONAB ----------EEGLEAGPSPTVLGAHPEMA---LDSQVPKVTPREEADSDV----G---- A8K9G1_HUMAN A8K9G1_HUMAN ----------EEGLEAGPSPTVLGAHAEMA---LDSQVPKVTPQEEADSDV----G---- FGD3_HUMAN FGD3_HUMAN ----------EEGLEAGPSPTVLGAHAEMA---LDSQVPKVTPQEEADSDV----G---- Q4RJT9_TETNG Q4RJT9_TETNG ----------EDAIDEEDHYDSVTETESVSC--CVTLGHKRDSTQDEDSDL-DEGSSGEI O93504_DANRE O93504_DANRE EHKQEYTHEEHKREHTHEEDQQEHTHEEHKRENTHDED-KREYTHEEDSDL---EEEEQE Q4V9K2_DANRE Q4V9K2_DANRE EHKQEYTHEEDKREHTHDVDKQEHTHEERKREYTHDEDKREYTHEEDSDL----EEEEQE MATCH CONSENSUS ????????????????????????????????????????????????????????????

Q4SSS2_TETNG Q4SSS2_TETNG ---------------------TTEQRLLNIAKELLQTERAYVARLHLLDQVSAGAGAWTS Q2L9D2_MOUSE Q2L9D2_MOUSE --------------------ETQEPEEKRVVRELLETEQAYVARLHLLD----------- Q3U195_MOUSE Q3U195_MOUSE --------------------ETQEPEEKRVVRELLETEQAYVARLHLLD----------- FGD2_MOUSE FGD2_MOUSE --------------------ETQEPEEKRVVRELLETEQAYVARLHLLD----------- Q0V7M5_BOVIN Q0V7M5_BOVIN ---------------------TQEPEEKKIVRELLETEQAYVARLHLLD----------- A8K304_HUMAN A8K304_HUMAN ----------------------TQEPEKKIVQELLETEQAYVARLHLLD----------- FGD2_HUMAN FGD2_HUMAN ---------------------GTQEPEKKIVQELLETEQAYVARLHLLD----------- FGD4_MOUSE FGD4_MOUSE RENGVNTMGLDTLDQHHEVKETNEQKLHKIATELLLTERAYVSRLDLLD----------- FGD4_RAT FGD4_RAT RENGLSTEGLNPLDQHHEVKETNEQKLHKIATELLLTERAYVSRLNLLD----------- Q49A55_HUMAN Q49A55_HUMAN ------------------------------------------------------------ B7Z8F9_HUMAN B7Z8F9_HUMAN RENGESPLELEQLDQHHEMKETNEQKLHKIANELLLTERAYVNRLDLLD----------- B7Z493_HUMAN B7Z493_HUMAN RENGESPLELEQLDQHHEMKETNEQKLHKIANELLLTERAYVNRLDLLD----------- FGD4_HUMAN FGD4_HUMAN RENGESPLELEQLDQHHEMKETNEQKLHKIANELLLTERAYVNRLDLLD----------- Q4SKH1_TETNG Q4SKH1_TETNG ------------------FQETNEQKLFNIASELLHTEKAYVARLNLLD----------- Q1L9G3_DANRE Q1L9G3_DANRE --------------------ETNEQKLYKIANELLQTEKAYVARLNLLD----------- B0V1Q7_DANRE B0V1Q7_DANRE --------------------MSVQQRVFNIANELLHTEKAYVSRLHLLD----------- Q2YDU5_RAT Q2YDU5_RAT EEEKEREIPVPPMERQESVELTVQQKVFHIANELLQTEKAYVSRLHLLD----------- FGD1_MOUSE FGD1_MOUSE EEEKEREIPVPPMERQESVELTVQQKVFHIANELLQTEKAYVSRLHLLD----------- Q3UG32_MOUSE Q3UG32_MOUSE EEEKEREIPVPPMERQESVELTVQQKVFHIANELLQTEKAYVSRLHLLD----------- A2ALP5_MOUSE A2ALP5_MOUSE EEEKEREIPVPPMERQESVELTVQQKVFHIANELLQTEKAYVSRLHLLD----------- Q921L2_MOUSE Q921L2_MOUSE EEEKEREIPVPPMERQESVELTVQQKVFHIANELLQTEKAYVSRLHLLD----------- A5D7I5_BOVIN A5D7I5_BOVIN EDEKDREVPAPLVERQESVELTVQQKVFHIANELLQTEKAYVSRLHLLD----------- B4DS99_HUMAN B4DS99_HUMAN EEEKDREIPVPLMERQESVELTVQQKVFHIANELLQTEKAYVSRLHLLD----------- FGD1_HUMAN FGD1_HUMAN EEEKDREIPVPLMERQESVELTVQQKVFHIANELLQTEKAYVSRLHLLD----------- FGD3_MOUSE FGD3_MOUSE EEPDPKVTLFRPQEDVSLTQCSDPQKLLHIAQELLHTEEAYVKRLHLLD----------- Q3TNB8_MOUSE Q3TNB8_MOUSE EEPDPKVTLFRPQEDVSLTQCSDPQKLLHIAQELLHTEEAYVKRLHLLD----------- Q3MHR4_BOVIN Q3MHR4_BOVIN EEPDPENNPSKV--DMDPAKCSEPQKLLHIAQELLHTEETYVKRLYLLD----------- Q58CS5_BOVIN Q58CS5_BOVIN EEPDPENNPSKV--DMDPAKCSEPQKLLHIAQELLHTEETYVKRLYLLD----------- Q0V8A6_BOVIN Q0V8A6_BOVIN EEPDPENNPSKV--DMDPAKCSEPQKLLHIAQELLHTEETYVKRLYLLD----------- Q9NXY1_HUMAN Q9NXY1_HUMAN EEPDSENTPQKADKDAGLAQHSGPQKLLHIAQELLHTEETYVKRLHLLD----------- FGD3_PONAB FGD3_PONAB EEPDSENTPQKADKDAGLAQHSGPQKLLHIAQELLHTEETYVKRLHLLD----------- A8K9G1_HUMAN A8K9G1_HUMAN EEPDSENTPQKADKDAGLAQHSGPQKLLHIAQELLHTEETYVKRLHLLD----------- FGD3_HUMAN FGD3_HUMAN EEPDSENTPQKADKDAGLAQHSGPQKLLHIAQELLHTEETYVKRLHLLD----------- Q4RJT9_TETNG Q4RJT9_TETNG HSLTDTQTGYLTDAHSEAHKCSEAQKLLNIARELLHTEEAYIKRLNLLD----------- O93504_DANRE O93504_DANRE EEEEDQNTEIK-------ASVCDPQKLLNIAKELLQTEEAYVKRLNLLD----------- Q4V9K2_DANRE Q4V9K2_DANRE EEEEDQNTGIK-------ASVCDPQKLLNIAKELLQTEEAYVKRLNLLD----------- MATCH CONSENSUS ????????????????????????Q????IA?ELL?TE??YV?RL?LLD???????????

Q4SSS2_TETNG Q4SSS2_TETNG SACRPATADPRLSFQVFCARLTEEA-GRGSFPPEVIKTIFSNVSSIYSFHSQFLLPDLET Q2L9D2_MOUSE Q2L9D2_MOUSE --------------QVFFQELLREAGRSKAFPEDVVKLIFSNISSIYRFHAQFFLPELQR Q3U195_MOUSE Q3U195_MOUSE --------------QVFFQELLREAGRSKAFPEDVVKLIFSNISSIYRFHAQFFLPELQR FGD2_MOUSE FGD2_MOUSE --------------QVFFQELLREAGRSKAFPEDVVKLIFSNISSIYRFHAQFFLPELQR Q0V7M5_BOVIN Q0V7M5_BOVIN --------------QVFFQELLKEARSSKAFPEDVVRLIFSNISSIYQFHSQFFLPELQR A8K304_HUMAN A8K304_HUMAN --------------QVFFQELLKTARSSKAFPEDVVRVIFSNISSIYQFHSQFFLPELQR FGD2_HUMAN FGD2_HUMAN --------------QVFFQELLKTARSSKAFPEDVVRVIFSNISSIYQFHSQFFLPELQR FGD4_MOUSE FGD4_MOUSE --------------QVFYCKLLEEA-NRGSFPAEMVNKIFSNISSINAFHSKFLLPELEK FGD4_RAT FGD4_RAT --------------QVFYCKLLEEA-NRGSFPAEMVNKIFSNISSINAFHSKFLLPELEK Q49A55_HUMAN Q49A55_HUMAN ----------------------------------MVNKIFSNISSINAFHSKFLLPELEK B7Z8F9_HUMAN B7Z8F9_HUMAN --------------QVFYCKLLEEA-NRGSFPAEMVNKIFSNISSINAFHSKFLLPELEK B7Z493_HUMAN B7Z493_HUMAN --------------QVFYCKLLEEA-NRGSFPAEMVNKIFSNISSINAFHSKFLLPELEK FGD4_HUMAN FGD4_HUMAN --------------QVFYCKLLEEA-NRGSFPAEMVNKIFSNISSINAFHSKFLLPELEK Q4SKH1_TETNG Q4SKH1_TETNG --------------QVFCAKLMEEA-NKGTFPVDVVKNIFSNISSIHTFHSQFLLPDLEK Q1L9G3_DANRE Q1L9G3_DANRE --------------KVFYTKLMEEA-RKDTFPVDVVKSIFSNITSINAFHSQFLLPDLEK B0V1Q7_DANRE B0V1Q7_DANRE --------------QVFCAQLMEEARARSSFPCEMVMGIFSNICSIYCFHQQFLLPALEK Q2YDU5_RAT Q2YDU5_RAT --------------QVFCARLLEEARNRSSFPADVVHGIFSNICSIYCFHQQFLLPELEK FGD1_MOUSE FGD1_MOUSE --------------QVFCARLLEEARNRSSFPADVVHGIFSNICSIYCFHQQFLLPELEK Q3UG32_MOUSE Q3UG32_MOUSE --------------QVFCARLLEEARNRSSFPADVVHGIFSNICSIYCFHQQFLLPELEK A2ALP5_MOUSE A2ALP5_MOUSE --------------QVFCARLLEEARNRSSFPADVVHGIFSNICSIYCFHQQFLLPELEK Q921L2_MOUSE Q921L2_MOUSE --------------QVFCARLLEEARNRSSFPADVVHGIFSNICSIYCFHQQFLLPELEK A5D7I5_BOVIN A5D7I5_BOVIN --------------QVFCARLLEEARNRSSFPADVVHGIFSNICSIYCFHQQFLLPELEK B4DS99_HUMAN B4DS99_HUMAN --------------QVFCARLLEEARNRSSFPADVVHGIFSNICSIYCFHQQFLLPELEK FGD1_HUMAN FGD1_HUMAN --------------QVFCARLLEEARNRSSFPADVVHGIFSNICSIYCFHQQFLLPELEK FGD3_MOUSE FGD3_MOUSE --------------QVFCTKLTE-----AGIPLEVTTGIFSNISSIYRFHGQFLLPELQK Q3TNB8_MOUSE Q3TNB8_MOUSE --------------QVFCTKLTE-----AGIPLEVTTGIFSNISSIYRFHGQFLLPELQK Q3MHR4_BOVIN Q3MHR4_BOVIN --------------QVFCTGLTE-----AGIPSEVTTGIFSNISSIYRFHGQFLLPELQA Q58CS5_BOVIN Q58CS5_BOVIN --------------QVFCTGLTE-----AGIPSEVTTGIFSNISSIYRFHGQFLLPELQA Q0V8A6_BOVIN Q0V8A6_BOVIN --------------QVFCTGLTE-----AGIPSEVTTGIFSNISSIYRFHGQFLLPELQA Q9NXY1_HUMAN Q9NXY1_HUMAN --------------QVFCTRLTD-----AGIPPEVIMGIFSNISSIHRFHGQFLLPELKT FGD3_PONAB FGD3_PONAB --------------QVFCTRLTD-----AGIPPEVIMGIFSNISSIHRFHGQFLLPELKT A8K9G1_HUMAN A8K9G1_HUMAN --------------QVFCTRLTD-----AGIPPEVIMGIFSNISSIHRFHGQFLLPELKT FGD3_HUMAN FGD3_HUMAN --------------QVFCTRLTD-----AGIPPEVIMGIFSNISSIHRFHGQFLLPELKT Q4RJT9_TETNG Q4RJT9_TETNG --------------QVFCTKLTE-----AGIPQDVITGIFSNISSIYCFHDKFLLPELKT O93504_DANRE O93504_DANRE --------------QVFCARLTE-----AGIPTDVITGIFSNISCIHRFHQQFLLPELHT Q4V9K2_DANRE Q4V9K2_DANRE --------------QVFCARLTE-----AGIPADVITGIFSNISCIHRFHQQFLLPELHT MATCH : ****: .* ** :*:** *. CONSENSUS ??????????????QVF???L??????????P??V???IFSNI?SI??FH?QFLLPEL??

Q4SSS2_TETNG Q4SSS2_TETNG CL-RCWSERPGLGHVLLQHGPFLRMYADYVRNFDQAVELVRVWNERSAAFRSITQDIQ-- Q2L9D2_MOUSE Q2L9D2_MOUSE RV-DDWAATPRIGDVIQKLAPFLKMYSEYVKNFERAAELLATWMDKSQPFQEVVTRIQ-- Q3U195_MOUSE Q3U195_MOUSE RV-DDWAATPRIGDVIQKLAPFLKMYSEYVKNFERAAELLATWMDKSQPFQEVVTRIQ-- FGD2_MOUSE FGD2_MOUSE RV-DDWAATPRIGDVIQKLAPFLKMYSEYVKNFERAAELLATWMDKSQPFQEVVTRIQ-- Q0V7M5_BOVIN Q0V7M5_BOVIN RL-DDWTTTPRIGDVIQKLAPFLKMYSEYVKNFERAIELLATWTDKSPPFQEVITRIQ-- A8K304_HUMAN A8K304_HUMAN RL-DDWTANPRIGDVIQKLAPFLKMYSEYVKNFERAAELLATWTDKSPLFQEVLTRIQ-- FGD2_HUMAN FGD2_HUMAN RL-DDWTANPRIGDVIQKLAPFLKMYSEYVKNFERAAELLATWTDKSPLFQEVLTRIQ-- FGD4_MOUSE FGD4_MOUSE RM-QEWETTPRIGDILQKLAPFLKMYGEYVKGFDNAVELVKTMTERVPQFKSVTEEIQ-- FGD4_RAT FGD4_RAT RM-QEWETTPRIGDILQKLAPFLKMYGEYVKGFDNAVELVKNMTERVPQFKSVTEEIQ-- Q49A55_HUMAN Q49A55_HUMAN RM-QEWETTPRIGDILQKLAPFLKMYGEYVKGFDNAMELVKNMTERIPQFKSVVEEIQ-- B7Z8F9_HUMAN B7Z8F9_HUMAN RM-QEWETTPRIGDILQKLAPFLKMYGEYVKGFDNAMELVKNMTERIPQFKSVVEEIQ-- B7Z493_HUMAN B7Z493_HUMAN RM-QEWETTPRIGDILQKLAPFLKMYGEYVKGFDNAMELVKNMTERIPQFKSVVEEIQ-- FGD4_HUMAN FGD4_HUMAN RM-QEWETTPRIGDILQKLAPFLKMYGEYVKGFDNAMELVKNMTERIPQFKSVVEEIQ-- Q4SKH1_TETNG Q4SKH1_TETNG RM-GEWTSTPRIGDILQKLTPFLKMYGEYVKNFDTAMELLKHWTDRSPQFKAIIQEIQVL Q1L9G3_DANRE Q1L9G3_DANRE RM-GEWTSTPRIGDILQKLTPFLKMYAEYVRNFDHAMDLLKQWIDRSPPFKAIILDIQ-- B0V1Q7_DANRE B0V1Q7_DANRE RM-EEWDLNPRIGDILQKLAPFLKMYGEYVKNFDRAMELVNTWMQRSSQFKTIIHNIQ-- Q2YDU5_RAT Q2YDU5_RAT RM-EEWDRYPRIGDILQKLAPFLKMYGEYVKNFDRAVELVNTWTERSTQFKVIIHEVQ-- FGD1_MOUSE FGD1_MOUSE RM-EEWDRYPRIGDILQKLAPFLKMYGEYVKNFDRAVELVNTWTERSTQFKVIIHEVQ-- Q3UG32_MOUSE Q3UG32_MOUSE RM-EEWDRYPRIGDILQKLAPFLKMYGEYVKNFDRAVELVNTWTERSTQFKVIIHEVQ-- A2ALP5_MOUSE A2ALP5_MOUSE RM-EEWDRYPRIGDILQKLAPFLKMYGEYVKNFDRAVELVNTWTERSTQFKVIIHEVQ-- Q921L2_MOUSE Q921L2_MOUSE RM-EEWDRYPRIGDILQKLAPFLKMYGEYVKNFDRAVELVNTWTERSTQFKVIIHEVQ-- A5D7I5_BOVIN A5D7I5_BOVIN RM-EEWDRYPRIGDILQKLAPFLKMYGEYVKNFDRAVELVNTWTERSTQFKVIIHEVQ-- B4DS99_HUMAN B4DS99_HUMAN RM-EEWDRYPRIGDILQKLAPFLKMYGEYVKNFDRAVELVNTWTERSTQFKVIIHEVQ-- FGD1_HUMAN FGD1_HUMAN RM-EEWDRYPRIGDILQKLAPFLKMYGEYVKNFDRAVELVNTWTERSTQFKVIIHEVQ-- FGD3_MOUSE FGD3_MOUSE RITEEWDTNPRLGDILQKLAPFLKMYGEYVKNFDRAMGLVSTWTQRSPQFKDVIHTIQ-- Q3TNB8_MOUSE Q3TNB8_MOUSE RITEEWDTNPRLGDILQKLAPFLKMYGEYVKNFDRAMGLVSTWTQRSPQFKDVIHTIQ-- Q3MHR4_BOVIN Q3MHR4_BOVIN RITNEWDVNPRLGDILQKLAPFLKMYGEYVKNFDRAMELVSTWTQRSPVFKDTVQSIQ-- Q58CS5_BOVIN Q58CS5_BOVIN RITNEWDVNPRLGDILQKLAPFLKMYGEYVKNFDRAMELVSTWTQRSPVFKDTVQSIQ-- Q0V8A6_BOVIN Q0V8A6_BOVIN RITNEWDVNPRLGDILQKLAPFLKMYGEYVKNFDRAMELVSTWTQRSPVFKDTVQSIQ-- Q9NXY1_HUMAN Q9NXY1_HUMAN RITEEWDTNPRLGDILQKLAPFLKMYGEYVKNFDRAVGLVSTWTQRSPLFKDVIHSIQ-- FGD3_PONAB FGD3_PONAB RITEEWDTNPRLGDILQKLAPFLKMYGEYVKNFDRAVGLVSTWTQRSPLFKDVVHSIQ-- A8K9G1_HUMAN A8K9G1_HUMAN RITEEWDTNPRLGDILQKLAPFLKMYGEYVKNFDRAVGLVSTWTQRSPLFKDVVHSIQ-- FGD3_HUMAN FGD3_HUMAN RITEEWDTNPRLGDILQKLAPFLKMYGEYVKNFDRAVGLVSTWTQRSPLFKDVVHSIQ-- Q4RJT9_TETNG Q4RJT9_TETNG RITGEWDSNPRIGDILQKLAPFMKMYGEYVKNFDRAMDLVNTWTQRSSQFKSVVQNIQ-- O93504_DANRE O93504_DANRE RITQEWSCNPRIGDILQKLAPFLKMYGEYVKNFDRSMELVSLWTQRSGTFKSTVQSIQ-- Q4V9K2_DANRE Q4V9K2_DANRE RITQEWSCNPRIGDILQKLAPFLKMYGEYVKNFDRSMELVSLWTQRSGTFKSTVQSIQ-- MATCH : * * :*.:: : **::**.:**:.*: : *: :: *: :* CONSENSUS R???EW???PR?GDILQKLAPFLKMY?EYVKNFD?A??L???WT?RS??FK??????Q??

Q4SSS2_TETNG Q4SSS2_TETNG ----------SQEVCGSLSLQHHMLEPVQRIPRYELLLKDYLKQLPQDSPDYELAHKSLQ Q2L9D2_MOUSE Q2L9D2_MOUSE ----------CSEASSSLTLQHHMLEPVQRIPRYELLLKEYVQKLPAQAPDLEDAQRALD Q3U195_MOUSE Q3U195_MOUSE ----------CSEASSSLTLQHHMLEPVQRIPRYELLLKEYVQKLPAQAPDLEDAQRALD FGD2_MOUSE FGD2_MOUSE ----------CSEASSSLTLQHHMLEPVQRIPRYELLLKEYVQKLPAQAPDLEDAQRALD Q0V7M5_BOVIN Q0V7M5_BOVIN ----------SSEASASLTLQHHMLEPVQRIPRYELLLKEYVQKLPGQAPDLADAQKALD A8K304_HUMAN A8K304_HUMAN ----------SSEASGSLTLQHHMLEPVQRIPRYELLLKEYIQKLPAQAPDQADAQKALD FGD2_HUMAN FGD2_HUMAN ----------SSEASGSLTLQHHMLEPVQRIPRYELLLKEYIQKLPAQAPDQADAQKALD FGD4_MOUSE FGD4_MOUSE ----------KQKICGSLTLQHHMLEPIQRIPRYEMLLKDYLKKLSPDSPDWNDAKKSLE FGD4_RAT FGD4_RAT ----------KQKICGSLTLQHHMLEPIQRIPRYEMLLKDYLKKLSPDAPDWNDAKKSLE Q49A55_HUMAN Q49A55_HUMAN ----------KQKICGSLTLQHHMLEPVQRIPRYEMLLKDYLRKLPPDSLDWNDAKKSLE B7Z8F9_HUMAN B7Z8F9_HUMAN ----------KQKICGSLTLQHHMLEPVQRIPRYEMLPKDYLRKLPPDSLDWNDAKKSLE B7Z493_HUMAN B7Z493_HUMAN ----------KQKICGSLTLQHHMLEPVQRIPRYEMLLKDYLRKLPPDSLDWNDAKKSLE FGD4_HUMAN FGD4_HUMAN ----------KQKICGSLTLQHHMLEPVQRIPRYEMLLKDYLRKLPPDSLDWNDAKKSLE Q4SKH1_TETNG Q4SKH1_TETNG TEMPGPSKERSQEICGSLTLQHHMLEPVQRVPRYEMLLKDYLKKLSEDDPDRRDAENFAG Q1L9G3_DANRE Q1L9G3_DANRE ----------SQEVCGNLTLQHHMLEPVQRVPRYEMLLKDYLKKLPPEHMDRRDAEKSLE B0V1Q7_DANRE B0V1Q7_DANRE ----------KEEMCGNLTLQHHMLEPVQRIPRYELLLKDYLHRLPEDADDFKDAQKSLE Q2YDU5_RAT Q2YDU5_RAT ----------KEEACGNLTLQHHMLEPVQRIPRYELLLKDYLLKLPHGSPDSKDAQKSLE FGD1_MOUSE FGD1_MOUSE ----------KEEACRNLTLQHHMLEPVQRIPRYELLLKDYLLKLPHGSPDSKDAQKSLE Q3UG32_MOUSE Q3UG32_MOUSE ----------KEEACGNLTLQHHMLEPVQRIPRYELLLKDYLLKLPHGSPDSKDAQKSLE A2ALP5_MOUSE A2ALP5_MOUSE ----------KEEACGNLTLQHHMLEPVQRIPRYELLLKDYLLKLPHGSPDSKDAQKSLE Q921L2_MOUSE Q921L2_MOUSE ----------KEEACGNLTLQHHMLEPVQRIPRYELLLKDYLLKLPHGSPDSKDAQKSLE A5D7I5_BOVIN A5D7I5_BOVIN ----------KEEACGNLTLQHHMLEPVQRIPRYELLLKDYLLKLPHGSPDSKDAQKSLE B4DS99_HUMAN B4DS99_HUMAN ----------KEEACGNLTLQHHMLEPVQRIPRYELLLKDYLLKLPHGSPDSKDAQKSLE FGD1_HUMAN FGD1_HUMAN ----------KEEACGNLTLQHHMLEPVQRIPRYELLLKDYLLKLPHGSPDSKDAQKSLE FGD3_MOUSE FGD3_MOUSE ----------KQEVCGNLTLQHHMLEPVQRVPRYELLLKDYLKRLPRDAPDRKDAERSLE Q3TNB8_MOUSE Q3TNB8_MOUSE ----------KQEVCGNLTLQHHMLEPVQRVPRYELLLKDYLKRLPRDAPDRKDAERSLE Q3MHR4_BOVIN Q3MHR4_BOVIN ----------KQELCGNLTLQHHMLEPVQRVPRYELLLKDYLKRLPEDAPDWKDAERSLE Q58CS5_BOVIN Q58CS5_BOVIN ----------KQELCGNLTLQHHMLEPVQRVPRYELLLKDYLKRLPEDAPDWKDAERSLE Q0V8A6_BOVIN Q0V8A6_BOVIN ----------KQELCGNLTLQHHMLEPVQRVPRYELLLKDYLKRLPEDAPDWKDAERSLE Q9NXY1_HUMAN Q9NXY1_HUMAN ----------KQEVCGNLTLQHHMLEPVQRVPRYELLLKDYLKRLPQDAPDRKDAERSLE FGD3_PONAB FGD3_PONAB ----------KQEVCGNLTLQHHMLEPVQRVPRYELLLKDYLKRLPQDAPDQKDAERSLE A8K9G1_HUMAN A8K9G1_HUMAN ----------KQEVCGNLTLQHHMLEPVQRVPRYELLLKDYLKRLPQDAPDRKDAERSLE FGD3_HUMAN FGD3_HUMAN ----------KQEVCGNLTLQHHMLEPVQRVPRYELLLKDYLKRLPQDAPDRKDAERSLE Q4RJT9_TETNG Q4RJT9_TETNG ----------KQEVCGNLTLQHHMLEPVQRIPRYELLLKDYLKKLPEDALDRKDAEKALE O93504_DANRE O93504_DANRE ----------KQEVCGNLTLQHHMLEPVQRIPRYELLLKDYLKKLPEGAADHRDAQNALE Q4V9K2_DANRE Q4V9K2_DANRE ----------KQEVCGNLTLQHHMLEPVQRIPRYELLLKDYLKKLPEGAADHRDAQNALE MATCH .: . .*:********:**:****:* *:*: :*. * *.. CONSENSUS ????????????E?CG?LTLQHHMLEPVQR?PRYE?LLKDYL??LP????D??DA???L?

Q4SSS2_TETNG Q4SSS2_TETNG TVSMAAT----------------HSNSAIHKADSL--------------KRVLEIYEMV- Q2L9D2_MOUSE Q2L9D2_MOUSE MIFSAAQ----------------HSNAAIAEMERL--------------QGLWDVYQRL- Q3U195_MOUSE Q3U195_MOUSE MIFSAAQ----------------HSNAAIAEMERL--------------QGLWDVYQRL- FGD2_MOUSE FGD2_MOUSE MIFSAAQ----------------HSNAAIAEMERL--------------QGLWDVYQRL- Q0V7M5_BOVIN Q0V7M5_BOVIN MIFSAAQ----------------HSNAAITEMERL--------------QELWDVYQRL- A8K304_HUMAN A8K304_HUMAN MIFSAAQ----------------HSNAAITEMERL--------------QDLWEVYQRL- FGD2_HUMAN FGD2_HUMAN MIFSAAQ----------------HSNAAITEMERL--------------QDLWEVYQRL- FGD4_MOUSE FGD4_MOUSE IISTAAS----------------HSNSAIRKMENL--------------KKLLEIYEML- FGD4_RAT FGD4_RAT IISTAAS----------------HSNSAIRKMENL--------------KKLLEIYEML- Q49A55_HUMAN Q49A55_HUMAN IISTAAS----------------HSNSAIRKMENL--------------KKLLEIYEML- B7Z8F9_HUMAN B7Z8F9_HUMAN IISTAAS----------------HSNSAIRKMENL--------------KKLLEIYEML- B7Z493_HUMAN B7Z493_HUMAN IISTAAS----------------HSNSAIRKMENL--------------KKLLEIYEML- FGD4_HUMAN FGD4_HUMAN IISTAAS----------------HSNSAIRKMENL--------------KKLLEIYEML- Q4SKH1_TETNG Q4SKH1_TETNG FIRVLSRFSRIPGDHRHGGYPLQQRHPKIREPEEAAGDIRDAGGGGGHRQPLQRVHQGGT Q1L9G3_DANRE Q1L9G3_DANRE IIGMAAT----------------HSNTAIRKTENL--------------KKLLEIYEML- B0V1Q7_DANRE B0V1Q7_DANRE LIATAAE----------------HSNAAIRKMERM--------------RKLLKVYELL- Q2YDU5_RAT Q2YDU5_RAT LIATAAE----------------HSNAAIRKMERM--------------HKLLKVYELL- FGD1_MOUSE FGD1_MOUSE LIATAAE----------------HSNAAIRKMERM--------------HKLLKVYELL- Q3UG32_MOUSE Q3UG32_MOUSE LIATAAE----------------HSNAAIRKMERM--------------HKLLKVYELL- A2ALP5_MOUSE A2ALP5_MOUSE LIATAAE----------------HSNAAIRKMERM--------------HKLLKVYELL- Q921L2_MOUSE Q921L2_MOUSE LIATAAE----------------HSNAAIRKMERM--------------HKLLKVYELL- A5D7I5_BOVIN A5D7I5_BOVIN LIATAAE----------------HSNAAIRKMERM--------------HKLLKVYELL- B4DS99_HUMAN B4DS99_HUMAN LIATAAE----------------HSNAAIRKMERM--------------HKLLKVYELL- FGD1_HUMAN FGD1_HUMAN LIATAAE----------------HSNAAIRKMERM--------------HKLLKVYELL- FGD3_MOUSE FGD3_MOUSE LISTAAD----------------HSNAAIRKMEKM--------------HKLLEVYEQL- Q3TNB8_MOUSE Q3TNB8_MOUSE LISTAAD----------------HSNAAIRKMEKM--------------HKLLEVYEQL- Q3MHR4_BOVIN Q3MHR4_BOVIN LISTAAN----------------HSNAAIRKMEKM--------------HKLLEVYERL- Q58CS5_BOVIN Q58CS5_BOVIN LISTAAN----------------HSNAAIRKMEKM--------------HKLLEVYERL- Q0V8A6_BOVIN Q0V8A6_BOVIN LISTAAN----------------HSNAAIRKMEKM--------------HKLLEVYERL- Q9NXY1_HUMAN Q9NXY1_HUMAN LISTAAN----------------HSNAAIRKVEKM--------------HKLLEVYEQL- FGD3_PONAB FGD3_PONAB LISTAAN----------------HSNAAIRKVEKM--------------HKLLEVYEQL- A8K9G1_HUMAN A8K9G1_HUMAN LISTAAN----------------HSNAAIRKVEKM--------------HKLLEVYEQL- FGD3_HUMAN FGD3_HUMAN LISTAAN----------------HSNAAIRKVEKM--------------HKLLEVYEQL- Q4RJT9_TETNG Q4RJT9_TETNG LISTAAN----------------HSNAAIRKMEKM--------------HKLLEVYERL- O93504_DANRE O93504_DANRE LISTAAN----------------HSNAAIRKMEKM--------------HKLLEVYERL- Q4V9K2_DANRE Q4V9K2_DANRE LISTAAN----------------HSNAAIRKMEKM--------------HKLLEVYERL- MATCH : : : :. * : : : : ::: CONSENSUS ?I??AA?????????????????HSN?AIRKME??????????????????LL??YE?L?

Q4SSS2_TETNG Q4SSS2_TETNG ----G-DEEVVNPANEFIREGRL---LKLAARNTSSMERHLFLVRTASALPENHAHPHRP Q2L9D2_MOUSE Q2L9D2_MOUSE ----GLEDDIVDPSNTLLREGPV---LKISFRRSDPMERYLVL----------------- Q3U195_MOUSE Q3U195_MOUSE ----GLEDDIVDPSNTLLREGPV---LKISFRRSDPMERYLVL----------------- FGD2_MOUSE FGD2_MOUSE ----GLEDDIVDPSNTLLREGPV---LKISFRRSDPMERYLVL----------------- Q0V7M5_BOVIN Q0V7M5_BOVIN ----GLEDDIVDPSNTLLREGPV---LKISFRRSGPMERYLFL----------------- A8K304_HUMAN A8K304_HUMAN ----GLEDDIVDPSNTLLREGPV---LKISFRRNDPMERYLFL----------------- FGD2_HUMAN FGD2_HUMAN ----GLEDDIVDPSNTLLREGPV---LKISFRRNDPMERYLFL----------------- FGD4_MOUSE FGD4_MOUSE ----GEEEDIVNPSNELIKEGQI---LKLAARNTSAQERYLFL----------------- FGD4_RAT FGD4_RAT ----GEEEDIVNPSNELIKEGQI---LKLAARNTSAQERYLFL----------------- Q49A55_HUMAN Q49A55_HUMAN ----GEEEDIVNPSNELIKEGQI---LKLAARNTSARERYLFL----------------- B7Z8F9_HUMAN B7Z8F9_HUMAN ----GEEEDIVNPSNELIKEGQI---LKLAARNTSAQERYLFL----------------- B7Z493_HUMAN B7Z493_HUMAN ----GEEEDIVNPSNELIKEGQI---LKLAARNTSAQERYLFL----------------- FGD4_HUMAN FGD4_HUMAN ----GEEEDIVNPSNELIKEGQI---LKLAARNTSAQERYLFL----------------- Q4SKH1_TETNG Q4SKH1_TETNG HPETGGQEHLGHGAIPLPGEGHSDIGMRKWAELSPVLGKTLTL----------------- Q1L9G3_DANRE Q1L9G3_DANRE ----GEEEDIVNPSNELIKEGHI---LKLAARNTSAMDRYLFL----------------- B0V1Q7_DANRE B0V1Q7_DANRE ----GGEEDIVNPTNELIKEGHI---LKLSAKNGTSQDRYLIL----------------- Q2YDU5_RAT Q2YDU5_RAT ----GGEEDIVSPTKELIKEGHI---LKLSAKNGTTQDRYLIL----------------- FGD1_MOUSE FGD1_MOUSE ----GGEEDIVSPTKELIKEGHI---LKLSAKNGTTQDRYLIL----------------- Q3UG32_MOUSE Q3UG32_MOUSE ----GGEEDIVSPTKELIKEGHI---LKLSAKNGTTQDRYLIL----------------- A2ALP5_MOUSE A2ALP5_MOUSE ----GGEEDIVSPTKELIKEGHI---LKLSAKNGTTQDRYLIL----------------- Q921L2_MOUSE Q921L2_MOUSE ----GGEEDIVSPTKELIKEGHI---LKLSAKNGTTQDRYLIL----------------- A5D7I5_BOVIN A5D7I5_BOVIN ----GGEEDIVSPTKELIKEGHI---LKLSAKNGTTQDRYLIL----------------- B4DS99_HUMAN B4DS99_HUMAN ----GGEEDIVSPTKELIKEGHI---LKLSAKNGTTQDRYLIL----------------- FGD1_HUMAN FGD1_HUMAN ----GGEEDIVSPTKELIKEGHI---LKLSAKNGTTQDRYLIL----------------- FGD3_MOUSE FGD3_MOUSE ----GGEEDIVNPANELIKEGSI---QKLSAKNGTTQDRHLFL----------------- Q3TNB8_MOUSE Q3TNB8_MOUSE ----GGEEDIVNPANELIKEGSI---QKLSAKNGTTQDRHLFL----------------- Q3MHR4_BOVIN Q3MHR4_BOVIN ----GGEEDIVNPANELIKEGHI---QKLSAKNGTTQDRHLFL----------------- Q58CS5_BOVIN Q58CS5_BOVIN ----GGEEDIVNPANELIKEGHI---QKLSAKNGTTQDRHLFL----------------- Q0V8A6_BOVIN Q0V8A6_BOVIN ----GGEEDIVNPANELIKEGHI---QKLSAKNGTTQTPN-------------------- Q9NXY1_HUMAN Q9NXY1_HUMAN ----GGEEDIVNPANELIKEGQI---QKLSAKNGTPQDRHLFL----------------- FGD3_PONAB FGD3_PONAB ----GGEEDIANPANELIKEGQI---QKLSAKNGTPQDRHLFL----------------- A8K9G1_HUMAN A8K9G1_HUMAN ----GGEEDIVNPANELIKEGQI---QKLSAKNGTPQDRHLFL----------------- FGD3_HUMAN FGD3_HUMAN ----GGEEDIVNPANELIKEGQI---QKLSAKNGTPQDRHLFL----------------- Q4RJT9_TETNG Q4RJT9_TETNG ----GGEEDIVNPANELIKEGHI---KKMSAKNGTAQDRYLYL----------------- O93504_DANRE O93504_DANRE ----GGEEDIVNPANELIKEGHI---KKMSAKNGSAQDRYLYL----------------- Q4V9K2_DANRE Q4V9K2_DANRE ----GGEEDIVNPANELIKEGHI---KKMSAKNGSAQDRYLYL----------------- MATCH * ::.: : : ** : . CONSENSUS ????G?EEDIV?P??ELI?EG??????K??A?N?????R?L?L?????????????????

Q4SSS2_TETNG Q4SSS2_TETNG PVHACATFNQQAAFVQFNNFLLCCTPKFSLVGQRFTVRCRIGVDGMQVQRTTNEDHPHSF Q2L9D2_MOUSE Q2L9D2_MOUSE ----------------FNNMLLYCVPRVLQVGAQFQVRTRIDVAGMKVRELTDAEFPHSF Q3U195_MOUSE Q3U195_MOUSE ----------------FNNMLLYCVPRVLQVGAQFQVRTRIDVAGMKVRELTDAEFPHSF FGD2_MOUSE FGD2_MOUSE ----------------FNNMLLYCVPRVLQVGAQFQVRTRIDVAGMKVRELTDAEFPHSF Q0V7M5_BOVIN Q0V7M5_BOVIN ----------------FNNMLLYCVPRVIQVGAHFQVRTRIDVAGMKVRELTDAEFPHSF A8K304_HUMAN A8K304_HUMAN ----------------FNNMLLYCVPRVIQVGAQFQVRTRIDVAGMKVRELMDAEFPHSF FGD2_HUMAN FGD2_HUMAN ----------------FNNMLLYCVPRVIQVGAQFQVRTRIDVAGMKVRELMDAEFPHSF FGD4_MOUSE FGD4_MOUSE ----------------FNNMLLYCVPRFSLVGSKFTVRTRVGIDGMKIVETHNEEYPHTF FGD4_RAT FGD4_RAT ----------------FNNMLLYCVPRFSLVGSKFTVRTRVGIDGMKIVETHNEEYPHTF Q49A55_HUMAN Q49A55_HUMAN ----------------FNNMLLYCVPKFSLVGSKFTVRTRVGIDGMKIVETQNEEYPHTF B7Z8F9_HUMAN B7Z8F9_HUMAN ----------------FNNMLLYCVPKFSLVGSKFTVRTRVGIDGMKIVETQNEEYPHTF B7Z493_HUMAN B7Z493_HUMAN ----------------FNNMLLYCVPKFSLVGSKFTVRTRVGIDGMKIVETQNEEYPHTF FGD4_HUMAN FGD4_HUMAN ----------------FNNMLLYCVPKFSLVGSKFTVRTRVGIDGMKIVETQNEEYPHTF Q4SKH1_TETNG Q4SKH1_TETNG ------SFFGLSHRSQFNNMLLYCVPKFSLGGAKYTVRTRIGIDGMKVLETTNEDYPHTF Q1L9G3_DANRE Q1L9G3_DANRE ----------------FNNMLLYCVPKFSLVGQKFTVRTRIGIEGMNVKETFNEDYPHTF B0V1Q7_DANRE B0V1Q7_DANRE ----------------FNDRLLYCVPKLRLIGQKFGVRARIDVDGMELKETSSMNVPRTF Q2YDU5_RAT Q2YDU5_RAT ----------------FNDRLLYCVPRLRLLGQKFSVRARIDVDGMELKESSNLNMPRTF FGD1_MOUSE FGD1_MOUSE ----------------FNDRLLYCVPRLRLLGQKFTVRARIDVDGMELKESSNLNMPRTF Q3UG32_MOUSE Q3UG32_MOUSE ----------------FNDRLLYCVPRLRLLGQKFSVRARIDVDGMELKESSNLNMPRTF A2ALP5_MOUSE A2ALP5_MOUSE ----------------FNDRLLYCVPRLRLLGQKFSVRARIDVDGMELKESSNLNMPRTF Q921L2_MOUSE Q921L2_MOUSE ----------------FNDRLLYCVPRLRLLGQKFSVRARIDVDGMELKESSNLNMPRTF A5D7I5_BOVIN A5D7I5_BOVIN ----------------FNDRLLYCVPRLRLLGQKFSVRARIDVDGMELKESSNLNLPRTF B4DS99_HUMAN B4DS99_HUMAN ----------------FNDRLLYCVPRLRLLGQKFSVRARIDVDGMELKESSNLNLPRTF FGD1_HUMAN FGD1_HUMAN ----------------FNDRLLYCVPRLRLLGQKFSVRARIDVDGMELKESSNLNLPRTF FGD3_MOUSE FGD3_MOUSE ----------------FNNVMLYCVPKLRLMGQKLSVREKMDISDLQVQDIVKPNAACTF Q3TNB8_MOUSE Q3TNB8_MOUSE ----------------FNNVMLYCVPKLRLMGQKLSVREKMDISDLQVQDIVKPNAACTF Q3MHR4_BOVIN Q3MHR4_BOVIN ----------------FNSMILYCVPKLRLMGQKFSVREKMDISGLQVQDIVKSGAAHTF Q58CS5_BOVIN Q58CS5_BOVIN ----------------FNSMILYCVPKLRLMGQKFSVREKMDISGLQVQDIVKSGAAHTF Q0V8A6_BOVIN Q0V8A6_BOVIN ----------------------------KLKGSH-------------------------- Q9NXY1_HUMAN Q9NXY1_HUMAN ----------------FNSMILYCVPKLRLMGQKFSVREKMDISGLQVQDIVKPNTAHTF FGD3_PONAB FGD3_PONAB ----------------FNSMILYCVPKLRLMGQKFSVREKMDISGLQVQDIVKPNTAHTF A8K9G1_HUMAN A8K9G1_HUMAN ----------------FNSMILYCVPKLRLMDQKFSVREKMDISGLQVQDIVKPNTAHTF FGD3_HUMAN FGD3_HUMAN ----------------FNSMILYCVPKLRLMGQKFSVREKMDISGLQVQDIVKPNTAHTF Q4RJT9_TETNG Q4RJT9_TETNG ----------------FNNMVLYCVPKLRLMGQKFSVRERIDIAGMEVQENVKQNLPHTF O93504_DANRE O93504_DANRE ----------------FNNMVLYCVPKLRLMGQKFSVRERIDIAGMEVHENVKQNVPHTF Q4V9K2_DANRE Q4V9K2_DANRE ----------------FNNMVLYCVPKLRLMGQKFSVRERIDIAGMEVHENVKQNVPHTF MATCH . : CONSENSUS ????????????????FN???LYCVP???L?G??F?VR??????G??????????????F

Q4SSS2_TETNG Q4SSS2_TETNG QVSGKERTLELQASSEQDRDEWIKE-------------IQEAIDTFQEKNETF----RLA Q2L9D2_MOUSE Q2L9D2_MOUSE LVSGKQRTLELQARSRDEMVSWMQA-------------CQAAIDQVEKRSETF---KAAV Q3U195_MOUSE Q3U195_MOUSE LVSGKQRTLELQARSRDEMVSWMQA-------------CQAAIDQVEKRSETF---KAAV FGD2_MOUSE FGD2_MOUSE LVSGKQRTLELQARSRDEMVSWMQA-------------CQAAIDQVEKRSETF---KAAV Q0V7M5_BOVIN Q0V7M5_BOVIN LVSGKQRTLELRARSQEEMISWLQA-------------CQAAIDQIEKRNETF---KAAV A8K304_HUMAN A8K304_HUMAN LVSGKQRTLELQARSQEEMISWMQA-------------FQAAIDQIEKRNETF---KAAA FGD2_HUMAN FGD2_HUMAN LVSGKQRTLELQARSQEEMISWMQA-------------FQAAIDQIEKRNETF---KAAA FGD4_MOUSE FGD4_MOUSE QISGKERTLELQASSEQDKEEWIKA-------------LQESIDAFHQRHETF----RNA FGD4_RAT FGD4_RAT QVSGKERTLELQASSEQDKEEWIKA-------------LQESIDAFHQRHETF----RNA Q49A55_HUMAN Q49A55_HUMAN QVSGKERTLELQASSAQDKEEWIKA-------------LQETIDAFHQRHETF----RNA B7Z8F9_HUMAN B7Z8F9_HUMAN QVSGKERTLELQASSAQDKEEWIKA-------------LQETIDAFHQRHETF----RNA B7Z493_HUMAN B7Z493_HUMAN QVSGKERTLELQASSAQDKEEWIKA-------------LQETIDAFHQRHETF----RNA FGD4_HUMAN FGD4_HUMAN QVSGKERTLELQASSAQDKEEWIKA-------------LQETIDAFHQRHETF----RNA Q4SKH1_TETNG Q4SKH1_TETNG QVSGKERILELQASSEQDKADWLKA-------------FQETIEIFQQKNESF----KNA Q1L9G3_DANRE Q1L9G3_DANRE QVSGKERTLELQASSKLDKESWIKA-------------FTETIDISLQKNETF----KSA B0V1Q7_DANRE B0V1Q7_DANRE LVSGKQRSLELQARTEEEKRDWIQA-------------IQATIQRHEQTLETF-RMLNCS Q2YDU5_RAT Q2YDU5_RAT LVSGKQRSLELQARTEEEKKDWVQA-------------INSTLLKHEQTLETF-KLLNST FGD1_MOUSE FGD1_MOUSE LVSGKQRSLELQARTEEEKKDWVQA-------------INSTLLKHEQTLETF-KLLNST Q3UG32_MOUSE Q3UG32_MOUSE LVSGKQRSLELQARTEEEKKDWVQA-------------INSTLLKHEQTLETF-KLLNST A2ALP5_MOUSE A2ALP5_MOUSE LVSGKQRSLELQARTEEEKKDWVQA-------------INSTLLKHEQTLETF-KLLNST Q921L2_MOUSE Q921L2_MOUSE LVSGKQRSLELQARTEEEKKDWVQA-------------INSTLLKHEQTLETF-KLLNST A5D7I5_BOVIN A5D7I5_BOVIN LVSGKQRSLELQARTEEEKKDWVQA-------------INSTLLKHEQTLETF-KLLNST B4DS99_HUMAN B4DS99_HUMAN LVSGKQRSLELQARTEEEKKDWVQA-------------INSTLLKHEQTLETF-KLLNST FGD1_HUMAN FGD1_HUMAN LVSGKQRSLELQARTEEEKKDWVQA-------------INSTLLKHEQTLETF-KLLNST FGD3_MOUSE FGD3_MOUSE IITGRKRSLELQTRTEEEKKEWIQV-------------IQATVEKHKQKSETF-RAFGGA Q3TNB8_MOUSE Q3TNB8_MOUSE IITGRKRSLELQTRTEEEKKEWIQV-------------IQATVEKHKQKSETF-RAFGGA Q3MHR4_BOVIN Q3MHR4_BOVIN IITGKKRSLELQTRTEEEKKEWIQV-------------IQATIEKHKQNSQTF-KAFSGS Q58CS5_BOVIN Q58CS5_BOVIN IITGKKRSLELQTRTEEEKKEWIQV-------------IQATIEKHKQNSQTF-KAFSGS Q0V8A6_BOVIN Q0V8A6_BOVIN ------------------------------------------------------------ Q9NXY1_HUMAN Q9NXY1_HUMAN IITGRKRSLELQTRTEEEKKEWIQI-------------IQATIEKHKQNSETF-KAFGGA FGD3_PONAB FGD3_PONAB IITGRKRSLELQTRTEEEKKEWIQI-------------IQATIEKHKQNSETF-KAFGGA A8K9G1_HUMAN A8K9G1_HUMAN IITGRKRSLELQTRTEEEKKEWIQI-------------IQATIEKHKQNSETF-KAFGGA FGD3_HUMAN FGD3_HUMAN IITGRKRSLELQTRTEEEKKEWIQI-------------IQATIEKHKQNSETF-KAFGGA Q4RJT9_TETNG Q4RJT9_TETNG AIIGKQRSLELQARTAEEKEDWIQARIPHTCTDACSHVILATIERHKQNSETFNKAFNSS O93504_DANRE O93504_DANRE TITGKQRSLELQARTAEERDDWIKV-------------ILGTIEKHKQNSETF-KAFNSS Q4V9K2_DANRE Q4V9K2_DANRE TITGKQRSLELQARTAEERDDWIKV-------------ILGTIEKHKQNSETF-KAFNSS MATCH CONSENSUS ???GK?R?LELQ?????????W????????????????????????????ETF???????

Q4SSS2_TETNG Q4SSS2_TETNG SRERGAGP--------------PRPPLD-------PRPRSERVHEMHGAVQRVHQEEAPL Q2L9D2_MOUSE Q2L9D2_MOUSE QGPQGDTQ--------------EPKPQVEELGLRAPQWV---------------RDKMVT Q3U195_MOUSE Q3U195_MOUSE QGPQGDTQ--------------EPKPQVEELGLRAPQWV---------------RDKMVT FGD2_MOUSE FGD2_MOUSE QGPQGDTQ--------------EPKPQVEELGLRAPQWV---------------RDKMVT Q0V7M5_BOVIN Q0V7M5_BOVIN QSPEGDPQ--------------EQELQSVELGLRAPQWV---------------RDKMVT A8K304_HUMAN A8K304_HUMAN QGPEGDIQ--------------EQELQSEDLGLRAPQWV---------------RDKMVT FGD2_HUMAN FGD2_HUMAN QGPEGDIQ--------------EQELQSEELGLRAPQWV---------------RDKMVT FGD4_MOUSE FGD4_MOUSE IAKENDIP--------------LEVSTA-ELGKRAPRWI---------------RDNEVT FGD4_RAT FGD4_RAT IAKENDIP--------------LEVSTA-ELGKRAPRWI---------------RDNEVT Q49A55_HUMAN Q49A55_HUMAN IAKDNDIH--------------SEVSTA-ELGKRAPRWI---------------RDNEVT B7Z8F9_HUMAN B7Z8F9_HUMAN IAKDNDIH--------------SEVSTA-ELGKRAPRWI---------------RDNEVT B7Z493_HUMAN B7Z493_HUMAN IAKDNDIH--------------SEVSTA-ELGKRAPRWI---------------RDNEVT FGD4_HUMAN FGD4_HUMAN IAKDNDIH--------------SEVSTA-ELGKRAPRWI---------------RDNEVT Q4SKH1_TETNG Q4SKH1_TETNG LKEGEEVS-------------------SAELGKRAPRWI---------------RDNEVT Q1L9G3_DANRE Q1L9G3_DANRE IKDTEEAS----------------DLNISELGKRAPRWI---------------RDNEVT B0V1Q7_DANRE B0V1Q7_DANRE FREEDLTP--------------PNSPNCSELGKRAPTPI---------------REKEVT Q2YDU5_RAT Q2YDU5_RAT NRDDEDTP--------------PNSPNV-DLGKRAPTPI---------------REKEVT FGD1_MOUSE FGD1_MOUSE NRDDEDTP--------------PNSPNV-DLGKRAPTPI---------------REKEVT Q3UG32_MOUSE Q3UG32_MOUSE NRDDEDTP--------------PNSPNV-DLGKRAPTPI---------------REKEVT A2ALP5_MOUSE A2ALP5_MOUSE NRDDEDTP--------------PNSPNV-DLGKRAPTPI---------------REKEVT Q921L2_MOUSE Q921L2_MOUSE NRDDEDTP--------------PNSPNV-DLGKRAPTPI---------------REKEVT A5D7I5_BOVIN A5D7I5_BOVIN NREDEDTP--------------PNSPNV-DLGKRAPTPI---------------REKEVT B4DS99_HUMAN B4DS99_HUMAN NREDEDTP--------------PNSPNV-DLGKRAPTPI---------------REKEVT FGD1_HUMAN FGD1_HUMAN NREDEDTP--------------PNSPNV-DLGKRAPTPI---------------REKEVT FGD3_MOUSE FGD3_MOUSE CSQDEEPTLSPDQPVMSTSSVEPAGVADSNGGTPGIESR--------KSSSKTRRDKEKP Q3TNB8_MOUSE Q3TNB8_MOUSE CSQDEEPTLSPDQPVMSTSSVEPAGVADSNGGTPGIESR--------KSSSKTRRDKEKP Q3MHR4_BOVIN Q3MHR4_BOVIN FSQDENSPLTPEPPMMSPSSEVPAVPANSGGGVSGSEPR--------RGSSKTRRDKEKQ Q58CS5_BOVIN Q58CS5_BOVIN FSQDENSPLTPEPPMMSPSSEVPAVPANSGGGVSGSEPR--------RGSSKTRRDKEKQ Q0V8A6_BOVIN Q0V8A6_BOVIN ------------------------------------------------------------ Q9NXY1_HUMAN Q9NXY1_HUMAN FSQDEDPSLSPDMPITSTSPVEPVVTTEGSSGAAGLEPR--------KLSSKTRRDKEKQ FGD3_PONAB FGD3_PONAB FSQDEDPSLSPDMPITSTSPVEPVVTTEGGSGAAGLEPR--------KLSSKTRRDKEKQ A8K9G1_HUMAN A8K9G1_HUMAN FSQDEDPSLSPDMPITSTSPVEPVVTTEGSSGAAGLEPR--------KLSSKTRRDKEKQ FGD3_HUMAN FGD3_HUMAN FSQDEDPSLSPDMPITSTSPVEPVVTTEGSSGAAGLEPR--------KLSSKTRRDKEKQ Q4RJT9_TETNG Q4RJT9_TETNG FSREEDHI--------------PDSP-----GPWGSTSADSDGEKLHERKSSRKKDKEKQ O93504_DANRE O93504_DANRE FSREDEHT--------------PDSP----LGPCSNTSICETDGAQHERKSSKKREKERE Q4V9K2_DANRE Q4V9K2_DANRE FSREDEHT--------------PDSP----LGPCSNTSICETDGAQHERKSSKKREKERE MATCH CONSENSUS ???????????????????????????????G??????????????????????R?????

Q4SSS2_TETNG Q4SSS2_TETNG QGLRLRELPDEARAPRAEPRLTAPLSPQVVCWRCSDYKVALEYDGNRLNKVCKSCYSILS Q2L9D2_MOUSE Q2L9D2_MOUSE MCMRCQEPFNALTRRRHHCRACG----YVVCAKCSDYRAELKYDSNRPNRVCLTCYTFLT Q3U195_MOUSE Q3U195_MOUSE MCMRCQEPFNALTRRRHHCRACG----YVVCAKCSDYRAELKYDSNRPNRVCLTCYTFLT FGD2_MOUSE FGD2_MOUSE MCMRCQEPFNALTRRRHHCRACG----YVVCAKCSDYRAELKYDSNRPNRVCLTCYTFLT Q0V7M5_BOVIN Q0V7M5_BOVIN MCMRCQEPFNALTRRRHHCRACG----YVVCARCSDYRAELKYDANRPNRVCLDCYTFLT A8K304_HUMAN A8K304_HUMAN MCMRCQEPFNALTRRRHHCRACG----YVVCARCSDYRAELKYDDNRPNRVCLHCYAFLT FGD2_HUMAN FGD2_HUMAN MCMRCQEPFNALTRRRHHCRACG----YVVCARCSDYRAELKYDDNRPNRVCLHCYAFLT FGD4_MOUSE FGD4_MOUSE MCMKCKESFNALTRRRHHCRACG----HVVCWKCSDYKAQLEYDGGRLNKVCKDCYQIIS FGD4_RAT FGD4_RAT MCMKCKESFNALTRRRHHCRACG----HVVCWKCSDYKAQLEYDGGRLNKVCKDCYQIMS Q49A55_HUMAN Q49A55_HUMAN MCMKCKEPFNALTRRRHHCRACG----YVVCWKCSDYKAQLEYDGGKLSKVCKDCYQIIS B7Z8F9_HUMAN B7Z8F9_HUMAN MCMKCKEPFNALTRRRHHCRACG----YVVCWKCSDYKAQLEYDGGKLSKVCKDCYQIIS B7Z493_HUMAN B7Z493_HUMAN MCMKCKEPFNALTRRRHHCRACG----YVVCWKCSDYKAQLEYDGGKLSKVCKDCYQIIS FGD4_HUMAN FGD4_HUMAN MCMKCKEPFNALTRRRHHCRACG----YVVCWKCSDYKAQLEYDGGKLSKVCKDCYQIIS Q4SKH1_TETNG Q4SKH1_TETNG MCMKCKEPFNALTRRRHHCRACG----YVVCWKCSDNKVALEYDGNKINKVCKDCFSILK Q1L9G3_DANRE Q1L9G3_DANRE MCMKCKEGFNAITRRRHHCRACG----YVVCWKCSDYKATLEYDGNKISKVCKHCYFILT B0V1Q7_DANRE B0V1Q7_DANRE LCMKCQEPFNSITKRRHHCKACG----HVVCGKCSEFRARLLYDNNRANRVCIDCYTMLV Q2YDU5_RAT Q2YDU5_RAT MCMRCQEPFNSITKRRHHCKACG----HVVCGKCSEFRARLIYDNNRSNRVCTDCYVALH FGD1_MOUSE FGD1_MOUSE MCMRCQEPFNSITKRRHHCKACG----HVVCGKCSEFRARLIYDNNRSNRVCTDCYVALH Q3UG32_MOUSE Q3UG32_MOUSE MCMRCQEPFNSITKRRHHCKACG----HVVCGKCSEFRARLIYDNNRSNRVCTDCYVALH A2ALP5_MOUSE A2ALP5_MOUSE MCMRCQEPFNSITKRRHHCKACG----HVVCGKCSEFRARLIYDNNRSNRVCTDCYVALH Q921L2_MOUSE Q921L2_MOUSE MCMRCQEPFNSITKRRHHCKACG----HVVCGKCSEFRARLIYDNNRSNRVCTDCYVALH A5D7I5_BOVIN A5D7I5_BOVIN MCMRCQEPFNSITKRRHHCKACG----HVVCGKCSEFRARLVYDNNRSNRVCTDCYVALH B4DS99_HUMAN B4DS99_HUMAN MCMRCQEPFNSITKRRHHCKACG----HVSVGR--------------------------- FGD1_HUMAN FGD1_HUMAN MCMRCQEPFNSITKRRHHCKACG----HVVCGKCSEFRARLVYDNNRSNRVCTDCYVALH FGD3_MOUSE FGD3_MOUSE GCKSCGETFNSITKRRYRCKLCG----EVICRKCSEFKA----ENSKQSRVCRECFLEEP Q3TNB8_MOUSE Q3TNB8_MOUSE GCKSCGETFNSITKRRYRCKLCG----EVICRKCSEFKA----ENSKQSRVCRECFLEEP Q3MHR4_BOVIN Q3MHR4_BOVIN GCSSCGETFNSITKKKKK------------------------------------------ Q58CS5_BOVIN Q58CS5_BOVIN GCSSCGETFNSITKRKHHCKLCG----AVICGKCSEFKA----ENGRQSRVCKECFLTQP Q0V8A6_BOVIN Q0V8A6_BOVIN ------------------------------------------------------------ Q9NXY1_HUMAN Q9NXY1_HUMAN SCKSCGETFNSITKRRHHCKLCG----AVICGKCSEFKA----ENSRQSRVCRDCFLTQP FGD3_PONAB FGD3_PONAB SCKSCGETFNSITKRRHHCKLCG----VVICGKCSEFKA----ENSRQSRVCRECFLTQP A8K9G1_HUMAN A8K9G1_HUMAN SCKSCGETFNSITKRRHHCKLCG----AVICGKCSEFKA----ENSRQSRVCRDCFLTQP FGD3_HUMAN FGD3_HUMAN SCKSCGETFNSITKRRHHCKLCG----AVICGKCSEFKA----ENSRQSRVCRDCFLTQP Q4RJT9_TETNG Q4RJT9_TETNG TCKGCNESFN-FTKRKHHCKSCG------------------------------------- O93504_DANRE O93504_DANRE TCKGCNEAFN-FTKRKHHCKSCG----AAVCGKC------LKVCDSRNIRMCRPCAEAEG Q4V9K2_DANRE Q4V9K2_DANRE TCKGCSEAFN-FTKRKHHCKSCG----AAVCGKC------LKVCDSRNIRMCRPCAEAEG MATCH CONSENSUS ?C??C?E?FN??T?RRHHC??CG?????V?C??CS???????????????VC??C?????

Q4SSS2_TETNG Q4SSS2_TETNG A-------QREERTDGRRQTLEFAVSLQSSRCLIRSFLFYGDD--PKTWQQLWCVFARTE Q2L9D2_MOUSE Q2L9D2_MOUSE GNV-----LPQGKEDKRRGILEKEASAAPDQSLVCSFLQLIGDKCSRSLPRSWCVIPRDD Q3U195_MOUSE Q3U195_MOUSE GNV-----LPQGKEDKRRGILEKEASAAPEQSLVCSFLQLIGDKCSSTLPRSWCVIPRDD FGD2_MOUSE FGD2_MOUSE GNV-----LPQGKEDKRRGILEKEASAAPEQSLVCSFLQLIGDKCSRSLPRSWCVIPRDD Q0V7M5_BOVIN Q0V7M5_BOVIN GNV-----LPEEKEDKRRGILEKGAVAGSEQSLICSFLQLLGDKWGKSGPRGWCVIPRDD A8K304_HUMAN A8K304_HUMAN GNV-----LPEAKEDKRRGILEKGSSATPDQSLMCSFLQLIGDKWGKSGPRGWCVIPRDD FGD2_HUMAN FGD2_HUMAN GNV-----LPEAKEDKRRGILEKGSSATPDQSLMCSFLQLIGDKWGKSGPRGWCVIPRDD FGD4_MOUSE FGD4_MOUSE G-------FTDSEEKKRRGILEIESAEVSGNSEVCSFLQYMEK--SKPWQKIWCVIPKQD FGD4_RAT FGD4_RAT G-------FAESEEKKRRGILEIESAEVSGNSEVCSFLQYMEK--SKPWQKIWCVIPKQD Q49A55_HUMAN Q49A55_HUMAN G-------FTDSEEKKRKGILEIESAEVSGNSVVCSFLQYMEK--SKPWQKAWCVIPKQD B7Z8F9_HUMAN B7Z8F9_HUMAN G-------FTDSEEKKRKGILEIESAEVSGNSVVCSFLQYMEK--SKPWQKAWCVIPKQD B7Z493_HUMAN B7Z493_HUMAN G-------FTDSEEKKRKGILEIESAEVSGNSVVCSFLQYMEK--SKPWQKAWCVIPKQD FGD4_HUMAN FGD4_HUMAN G-------FTDSEEKKRKGILEIESAEVSGNSVVCSFLQYMEK--SKPWQKAWCVIPKQD Q4SKH1_TETNG Q4SKH1_TETNG G--------EGLTEGKKKGILEIEAAQFTGSSIMCGFLQYCER--NKPWQKVWCVIPKKE Q1L9G3_DANRE Q1L9G3_DANRE GRT-----DSDDREGKKKGILEIEAAQFCGSSIMCGFLQYCER--NKPWQKVWCVIPEKE B0V1Q7_DANRE B0V1Q7_DANRE GVP-PSPASLSSSTQRRRSILEKQASVAAENSVLCSFLHHMEKGSGRGWQKAWFVIPENE Q2YDU5_RAT Q2YDU5_RAT GAPGSSPACSQHTPQRRRSILEKQASVAAENSVICSFLHYMEKG-GKGWHKAWFVVPENE FGD1_MOUSE FGD1_MOUSE GAPGSSPACSQHTPQRRRSILEKQASVAAENSVICSFLHYMEKG-GKGWHKAWFVVPENE Q3UG32_MOUSE Q3UG32_MOUSE GAPGSSPACSQHTPQRRRSILEKQASVAAENSVICSFLHYMEKG-GKGWHKAWFVVPENE A2ALP5_MOUSE A2ALP5_MOUSE GAPGSSPACSQHTPQRRRSILEKQASVAAENSVICSFLHYMEKG-GKGWHKAWFVVPENE Q921L2_MOUSE Q921L2_MOUSE GAPGSSPACSQHTPQRRRSILEKQASVAAENSVICSFLHYMEKG-GKGWHKAWFVVPENE A5D7I5_BOVIN A5D7I5_BOVIN GVPGSSPACSQHTPQRRRSILEKQASVAAENSVICSFLHYMEKG-GKGWHKAWFVVPENE B4DS99_HUMAN B4DS99_HUMAN ------------------------------------------------------------ FGD1_HUMAN FGD1_HUMAN GVPGSSPACSQHTPQRRRSILEKQASVAAENSVICSFLHYMEKG-GKGWHKAWFVVPENE FGD3_MOUSE FGD3_MOUSE LVP---PSPSSETPTELKQNAEKPPSVDPRPSLLCGTLNLSDD--GTTWNEVWAAIPESD Q3TNB8_MOUSE Q3TNB8_MOUSE LVP---PSPSSETPTELKQNAEKPPSVDPRPSLLCGTLNLSDD--GTTWNEVWAAIPESD Q3MHR4_BOVIN Q3MHR4_BOVIN ------------------------------------------------------------ Q58CS5_BOVIN Q58CS5_BOVIN VAH---LNLSLEEPLEPKQSTEKPVAAEPPPSLLCGPLQVSDG--GTAWSKAWAAISESD Q0V8A6_BOVIN Q0V8A6_BOVIN ------------------------------------------------------------ Q9NXY1_HUMAN Q9NXY1_HUMAN VAP---------------------ESTEVGAPSSCSP----------------------- FGD3_PONAB FGD3_PONAB VAP---ESPSPEAPAKPRRSTEKTPTADPQPSLLCGPLRLSES--GETWSEVWAAIPMSD A8K9G1_HUMAN A8K9G1_HUMAN VAP----------------ESTETPTADPQPSLLCGPLRLSES--GETWSEVWAAIPMSD FGD3_HUMAN FGD3_HUMAN VAP---------------ESTEKTPTADPQPSLLCGPLRLSES--GETWSEVWAAIPMSD Q4RJT9_TETNG Q4RJT9_TETNG ---------------------ARQLSLTTENCLLCGQLHVQEK--GKTWTKMWAAVTRTE O93504_DANRE O93504_DANRE A-------AGGATEHKKR--VEKQLSVSQ------------------------------- Q4V9K2_DANRE Q4V9K2_DANRE A-------AGGATEHKKR--VEKQLSVSQ------------------------------- MATCH CONSENSUS ?????????????????????E????????????C??L??????????????W???????

Q4SSS2_TETNG Q4SSS2_TETNG PATLQLFAAQQVGQETGTTSPAIKALTFFPRRQDAAPLSCIPLSGCEVDESCPELQGLP- Q2L9D2_MOUSE Q2L9D2_MOUSE P--LVLY--------------------VYAAPQDTKAHTSIPLLGYQVI---SGPQGDP- Q3U195_MOUSE Q3U195_MOUSE P--LVLY--------------------VYAAPQDTKAHTSIPLLGYQVI---SGPQGDP- FGD2_MOUSE FGD2_MOUSE P--LVLY--------------------VYAAPQDTKAHTSIPLLGYQVI---SGPQGDP- Q0V7M5_BOVIN Q0V7M5_BOVIN P--LVLY--------------------VYAAPQDMRAHTSIPLLGYQVT---AGPQADP- A8K304_HUMAN A8K304_HUMAN P--LVLY--------------------VYAAPQDMRAHTSIPLLGYQVT---VGPQGDP- FGD2_HUMAN FGD2_HUMAN P--LVLY--------------------VYAAPQDMRAHTSIPLLGYQVT---VGPQGDP- FGD4_MOUSE FGD4_MOUSE P--LVLY--------------------MYGAPQDVRAQATIPLLGYVVDD-MPKSADLP- FGD4_RAT FGD4_RAT P--LVLY--------------------MYGAPQDVRAQATIPLLGYIVDD-MPKSADLP- Q49A55_HUMAN Q49A55_HUMAN P--LVLY--------------------MYGAPQVSKPHLS------EGTDALGGKGKRVD B7Z8F9_HUMAN B7Z8F9_HUMAN P--LVLY--------------------MYGAPQDVRAQATIPLLGYVVDE-MPRSADLP- B7Z493_HUMAN B7Z493_HUMAN P--LVLY--------------------MYGAPQDVRAQATIPLLGYVVDE-MPRSADLP- FGD4_HUMAN FGD4_HUMAN P--LVLY--------------------MYGAPQDVRAQATIPLLGYVVDE-MPRSADLP- Q4SKH1_TETNG Q4SKH1_TETNG A--VVLY--------------------LYGAPQDVKAQCTIPLLGYSVD----DSVRPAD Q1L9G3_DANRE Q1L9G3_DANRE A--LVLY--------------------LYGAPQDVKAQSTIPLLGYHVED-NPRATDPP- B0V1Q7_DANRE B0V1Q7_DANRE P--LVLY--------------------IYGAPQDVKAQRSLPLIGFEVS--LPESGDRLE Q2YDU5_RAT Q2YDU5_RAT P--LVLY--------------------IYGAPQDVKAQRSLPLIGFEVG--PPEAGERPD FGD1_MOUSE FGD1_MOUSE P--LVLY--------------------IYGAPQDVKAQRSLPLIGFEVG--PPEAGERPD Q3UG32_MOUSE Q3UG32_MOUSE P--LVLY--------------------IYGAPQDVKAQRSLPLIGFEVG--PPEAGERPD A2ALP5_MOUSE A2ALP5_MOUSE P--LVLY--------------------IYGAPQDVKAQRSLPLIGFEVG--PPEAGERPD Q921L2_MOUSE Q921L2_MOUSE P--LVLY--------------------IYGAPQDVKAQRSLPLIGFEVG--PPEAGERPD A5D7I5_BOVIN A5D7I5_BOVIN P--LVLY--------------------IYGAPQDVKAQRSLPLIGFEVG--PPEAGERPD B4DS99_HUMAN B4DS99_HUMAN ------------------------------------------------------------ FGD1_HUMAN FGD1_HUMAN P--LVLY--------------------IYGAPQDVKAQRSLPLIGFEVG--PPEAGERPD FGD3_MOUSE FGD3_MOUSE P--QVLD--------------------LLAGSQAGRLLYSIPLSGCNIT--MPDPEEGLE Q3TNB8_MOUSE Q3TNB8_MOUSE P--QVLD--------------------LLAGSQAGRLLYSIPLSGCNIT--MPDPEEGLE Q3MHR4_BOVIN Q3MHR4_BOVIN ------------------------------------------------------------ Q58CS5_BOVIN Q58CS5_BOVIN SLELVLH--------------------LHEGSQDGQLLHAIPLSGCRVS--VLDPAERLD Q0V8A6_BOVIN Q0V8A6_BOVIN ------------------------------------------------------------ Q9NXY1_HUMAN Q9NXY1_HUMAN ---------------------------------------------------PGGAAEPPD FGD3_PONAB FGD3_PONAB P--QVLH--------------------LQGGSQDGWLPRTIPLPSCKLS--VPDPEERLD A8K9G1_HUMAN A8K9G1_HUMAN P--QVLH--------------------LQGGSQDGRLPRTIPLPSCKLS--VPDPEERLD FGD3_HUMAN FGD3_HUMAN P--QVLH--------------------LQGGSQDGRLPRTIPLPSCKLS--VPDPEERLD Q4RJT9_TETNG Q4RJT9_TETNG P--LVLY--------------------LQSSGQDSKGARAVPLPGFEVSVIPPSSGEKPE O93504_DANRE O93504_DANRE ---------------------------LSSSQRSGKGE---------------------- Q4V9K2_DANRE Q4V9K2_DANRE ---------------------------LSSSQRSGKGE---------------------- MATCH CONSENSUS ????VL??????????????????????????Q????????PL?????????????????

Q4SSS2_TETNG Q4SSS2_TETNG ---CFRLKQPSGAHTFCCEGAELQRSWLAVLKDALTGKTR-------------------- Q2L9D2_MOUSE Q2L9D2_MOUSE --RVFQLQQSGQQYTFKAESVELQGRWVTAIKRAASGRT-PEGP--------DEEDVSD- Q3U195_MOUSE Q3U195_MOUSE --RVFQLQQSGQQYTFKAESVELQGRWVTAIKRAASGRT-PEGP--------DEEDVSD- FGD2_MOUSE FGD2_MOUSE --RVFQLQQSGQQYTFKAESVELQGRWVTAIKRAASGRT-PEGP--------DEEDVSD- Q0V7M5_BOVIN Q0V7M5_BOVIN --RVFQLQQSGQLYTFKAESEELKGRWVKAMERAASGWI-PGGP--------NDKDLSD- A8K304_HUMAN A8K304_HUMAN --RVFQLQQSGQLYTFKAETEELKGRWVKAMERAASGWS-PSWP--------NDGDLSD- FGD2_HUMAN FGD2_HUMAN --RVFQLQQSGQLYTFKAETEELKGRWVKAMERAASGWS-PSWP--------NDGDLSD- FGD4_MOUSE FGD4_MOUSE --HSFKLTQSKSVHSFAADNEELKQKWLKIILLAVTGET-PDGP-------------SEH FGD4_RAT FGD4_RAT --HSFKLTQSKSVHSFAADSEELKQKWLKIILLAVTGET-PDGP-------------SEH Q49A55_HUMAN Q49A55_HUMAN SGLKICRTRVQAVSLFH------------------------------------------- B7Z8F9_HUMAN B7Z8F9_HUMAN --HSFKLTQSKSVHSFAADSEELKQKWLKVILLAVTGET-PGGP--------NEHPAT-- B7Z493_HUMAN B7Z493_HUMAN --HSFKLTQSKSVHSFAADSEELKQKWLKVILLAVTGET-PGGP--------NEHPAT-- FGD4_HUMAN FGD4_HUMAN --HSFKLTQSKSVHSFAADSEELKQKWLKVILLAVTGET-PGGP--------NEHPAT-- Q4SKH1_TETNG Q4SKH1_TETNG PAASFRLSQSKSIHSFAAESEEIKQRWLKVIRVAVTGEE-PESP---------------- Q1L9G3_DANRE Q1L9G3_DANRE --ASFRLSQSKSIHSFAAESEELKQRWLKVIRMAVTGEV-PESP---------------E B0V1Q7_DANRE B0V1Q7_DANRE RRFAFKMSQSHLTVYFSADCEELQRRWMEVLSRAGR------------------------ Q2YDU5_RAT Q2YDU5_RAT RRHVFKITQSHLSWYFSPETEELQRRWMAVLGRAGRGDTFCPGPTLSEDKEMEETTVAAS FGD1_MOUSE FGD1_MOUSE RRHVFKITQSHLSWYFSPETEELQRRWMAVLGRAGRGDTFCPGPTLSEDKEMEETPVAAS Q3UG32_MOUSE Q3UG32_MOUSE RRHVFKITQSHLSWYFSPETEELQRRWMAVLGRAGRGDTFCPGPTLSEDKEMEETPVAAS A2ALP5_MOUSE A2ALP5_MOUSE RRHVFKITQSHLSWYFSPETEELQRRWMAVLGRAGRGDTFCPGPTLSEDKEMEETPVAAS Q921L2_MOUSE Q921L2_MOUSE RRHVFKITQSHLSWYFSPETEELQRRWMAVLGRAGRGDTFCPGPTLSEDKEMEETPVAAS A5D7I5_BOVIN A5D7I5_BOVIN RRHVFKITQSHLSWYFSPETEELQRRWMAVLGRAGRGDTFCPGPTLSEDREMEEVPVAAS B4DS99_HUMAN B4DS99_HUMAN -----------------------------------QGQS--------------------- FGD1_HUMAN FGD1_HUMAN RRHVFKITQSHLSWYFSPETEELQRRWMAVLGRAGRGDTFCPGPTLSEDREMEEAPVAAL FGD3_MOUSE FGD3_MOUSE AGCAWKLHQGSQTWWLSAPSTKLQQCWLKALGTAVHGDTAGDRP---------------- Q3TNB8_MOUSE Q3TNB8_MOUSE AGCAWKLHQGSQTWWLSAPSTKLQQCWLKALGTAVHGDTAGDRP---------------- Q3MHR4_BOVIN Q3MHR4_BOVIN ------------------------------------------------------------ Q58CS5_BOVIN Q58CS5_BOVIN ARHVWQLQQAQQSLYLSAPSAELQQQWLEALSSAAHRHSSQASL---------------- Q0V8A6_BOVIN Q0V8A6_BOVIN ------------------------------------------------------------ Q9NXY1_HUMAN Q9NXY1_HUMAN TCSCAP----------------------AALAASAFGVSLGPG----------------- FGD3_PONAB FGD3_PONAB SGHVWKLQWAKQSWYLSASSAELQQRWLETLSTAARGDTAQDSP---------------- A8K9G1_HUMAN A8K9G1_HUMAN SGHVWKLQWAKQSWYLSASSAELQQQWLETLSTAAHGDTAQDSP---------------- FGD3_HUMAN FGD3_HUMAN SGHVWKLQWAKQSWYLSASSAELQQQWLETLSTAAHGDTAQDSP---------------- Q4RJT9_TETNG Q4RJT9_TETNG GKHGLRLSHTQQTLLLSAPDAEHQARWLELLSKAARG--------------LETEWQFGA O93504_DANRE O93504_DANRE ----------------EVEQEQILHR---------------------------------- Q4V9K2_DANRE Q4V9K2_DANRE ----------------EVEQEQILHR---------------------------------- MATCH CONSENSUS ??????????????????????????W??????A??G???????????????????????

Q4SSS2_TETNG Q4SSS2_TETNG ---------------- Q2L9D2_MOUSE Q2L9D2_MOUSE ---------------- Q3U195_MOUSE Q3U195_MOUSE ---------------- FGD2_MOUSE FGD2_MOUSE ---------------- Q0V7M5_BOVIN Q0V7M5_BOVIN ---------------- A8K304_HUMAN A8K304_HUMAN ---------------- FGD2_HUMAN FGD2_HUMAN ---------------- FGD4_MOUSE FGD4_MOUSE LATLNNLPGPKKKSEC FGD4_RAT FGD4_RAT LDTLDNLPGPKEKSEC Q49A55_HUMAN Q49A55_HUMAN ---------------- B7Z8F9_HUMAN B7Z8F9_HUMAN ---LDDHPEPKKKSEC B7Z493_HUMAN B7Z493_HUMAN ---LDDHPEPKKKSEC FGD4_HUMAN FGD4_HUMAN ---LDDHPEPKKKSEC Q4SKH1_TETNG Q4SKH1_TETNG -----ETNGSGLDNNN Q1L9G3_DANRE Q1L9G3_DANRE ENSSAEITEELNSNGN B0V1Q7_DANRE B0V1Q7_DANRE ---------------- Q2YDU5_RAT Q2YDU5_RAT GATAEPPEASQTRDKT FGD1_MOUSE FGD1_MOUSE GATAEPPEASQTRDKT Q3UG32_MOUSE Q3UG32_MOUSE GATAEPPEASQTRDKT A2ALP5_MOUSE A2ALP5_MOUSE GATAEPPEASQTRDKT Q921L2_MOUSE Q921L2_MOUSE GATAEPPEASQTRDKT A5D7I5_BOVIN A5D7I5_BOVIN GATAEPSEAPQTRDKT B4DS99_HUMAN B4DS99_HUMAN ---------------- FGD1_HUMAN FGD1_HUMAN GATAEPPESPQTRDKT FGD3_MOUSE FGD3_MOUSE --GASQPQAPAGTDTP Q3TNB8_MOUSE Q3TNB8_MOUSE --GASQPQAPAGTDTP Q3MHR4_BOVIN Q3MHR4_BOVIN ---------------- Q58CS5_BOVIN Q58CS5_BOVIN --GAPQPQAPAAP--- Q0V8A6_BOVIN Q0V8A6_BOVIN ---------------- Q9NXY1_HUMAN Q9NXY1_HUMAN ---------------- FGD3_PONAB FGD3_PONAB --GALQPQVPTGAAAP A8K9G1_HUMAN A8K9G1_HUMAN --GALQLQVPMGAAAP FGD3_HUMAN FGD3_HUMAN --GALQLQVPMGAAAP Q4RJT9_TETNG Q4RJT9_TETNG CCTVCIVQCMEKKKDI O93504_DANRE O93504_DANRE ---------------- Q4V9K2_DANRE Q4V9K2_DANRE ---------------- MATCH CONSENSUS ????????????????


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