Alignment of the gene Family HBG044411 of HOVERGEN

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Threshold: 50% 80% 100%
Size: Bigger Smaller Normal
Isoforms are ON
Q4R499_MACFA Q4R499_MACFA ------------------------------------------------------------ Q6NSC0_HUMAN Q6NSC0_HUMAN SFPKAPLKRFNDPSGCAPSPGAYDVKTLEVLKGPVSFQKSQRFKQQKESKQNLNVDKDTT Q05DM0_HUMAN Q05DM0_HUMAN SFPKAPLKRFNDPSGCAPSPGAYDVKTLEVLKGPVSFQKSQRFKQQKESKQNLNVDKDTT Q6PG44_HUMAN Q6PG44_HUMAN SFPKAPLKRFNDPSGCAPSPGAYDVKTLEVLKGPVSFQKSQRFKQQKESKQNLNVDKDTT B4E114_HUMAN B4E114_HUMAN ----------------------------------------------------------MT Q32N02_HUMAN Q32N02_HUMAN SFPKAPLKRFNDPSGCAPSPGAYDVKTLEVLKGPVSFQKSQRFKQQKESKQNLNVDKDTT B4DZK6_HUMAN B4DZK6_HUMAN SFPKAPLKRFNDPSGCAPSPGAYDVKTLEVLKGPVSFQKSQRFKQQKESKQNLNVDKDTT A8K3G2_HUMAN A8K3G2_HUMAN SFPKAPLKRFNDPSGCAPSPGAYDVKTLEVLKGPVSFQKSQRFKQQKESKQNLNVDKDTT HMMR_HUMAN HMMR_HUMAN SFPKAPLKRFNDPSGCAPSPGAYDVKTLEVLKGPVSFQKSQRFKQQKESKQNLNVDKDTT Q8VDR2_MOUSE Q8VDR2_MOUSE SFPKAPLKRFNDPSGCAPSPGAYDVKTSEATKGPVSFQKSQRFKNQRESQQNLNIDKDTT HMMR_MOUSE HMMR_MOUSE SFPKAPLKRFNDPSGCAPSPGAYDVKTSEATKGPVSFQKSQRFKNQRESQQNLSIDKDTT Q3UPW7_MOUSE Q3UPW7_MOUSE SFPKAPLKRFNDPSGCAPSPGAYDVKTSEATKGPVSFQKSQRFKNQRESQQNLNIDKDTT Q5NC88_MOUSE Q5NC88_MOUSE SFPKAPLKRFNDPSGCAPSPGAYDVKTSEATKGPVSFQKSQRFKNQRESQQNLNIDKDTT HMMR_RAT HMMR_RAT ------------------------------MGGGVSYV---------------------- Q9WUF7_RAT Q9WUF7_RAT SFPKAPLKRFNDPSGCAPSPGAYDVKTSESTKGPVSFQKSQRFKNQRESQQNLNIDKDTT MATCH CONSENSUS SFPKAPLKRFNDPSGCAPSPGAYDVKT?E??KGPVSFQKSQRFK?Q?ES?QNL??DKDTT

Q4R499_MACFA Q4R499_MACFA ------------------------------------------------------------ Q6NSC0_HUMAN Q6NSC0_HUMAN LPASARKVKSSESK----------------ICVLLQERGAQDRRIQDLETELEKMEARLN Q05DM0_HUMAN Q05DM0_HUMAN LPASARKVKSSESK----------------IRVLLQERGAQDRRIQDLETELEKMEARLN Q6PG44_HUMAN Q6PG44_HUMAN LPASARKVKSSESK----------------IRVLLQERGAQDRRIQDLETELEKMEARLN B4E114_HUMAN B4E114_HUMAN LL----------------------------IRVLLQERGAQDRRIQDLETELEKMEARLN Q32N02_HUMAN Q32N02_HUMAN LPASARKVKSSESKKESQKNDKDLKILEKEICVLLQERGAQDRRIQDLETELEKMEARLN B4DZK6_HUMAN B4DZK6_HUMAN LPASARKVKSSESKKESQKNDKDLKILEKEIRVLLQERGAQDRRIQDLETE--------- A8K3G2_HUMAN A8K3G2_HUMAN LPASARKVKSSESK----------------IRVLLQERGAQDRRIQDLETELEKMEARLN HMMR_HUMAN HMMR_HUMAN LPASARKVKSSESK-ESQKNDKDLKILEKEIRVLLQERGAQDRRIQDLETELEKMEARLN Q8VDR2_MOUSE Q8VDR2_MOUSE LLASAKKAKKSVSKKDSQKNDKDVKRLEKEIRVLLQERGTQDKRIQDMESELEKTEAKLN HMMR_MOUSE HMMR_MOUSE LLASAKKAKKSVSKKDSQKNDKDVKRLEKEIRALLQERGTQDKRIQDMESELEKTEAKLN Q3UPW7_MOUSE Q3UPW7_MOUSE LLASAKKAKKSVSKKDSQKNDKDVKRLEKEIRALLQERGTQDKRIQDMESELEKTEAKLN Q5NC88_MOUSE Q5NC88_MOUSE LLASAKKAKKSVSKKDSQKNDKDVKRLEKEIRALLQERGTQDKRIQDMESELEKTEAKLN HMMR_RAT HMMR_RAT ------------------------------------------------------------ Q9WUF7_RAT Q9WUF7_RAT LLASAKKAKTLVSKKESQKNDKDVKRLEKEIHVLLQERGTQDKRIQDMESELENTEANLN MATCH CONSENSUS L?ASA?K?K???SK????????????????I??LLQERG?QD?RIQD?E?ELE??EA?LN

Q4R499_MACFA Q4R499_MACFA ------------------------------------------------------------ Q6NSC0_HUMAN Q6NSC0_HUMAN AALREKTSLSANNATLEKQLIELTRTNELLKSKFSENGNQKNLRILSLELMKLRNKRETK Q05DM0_HUMAN Q05DM0_HUMAN AALREKTSLSANNATLEKQLIELTRTNELLKSKFSENGNQKNLRILSLELMKLRNKRETK Q6PG44_HUMAN Q6PG44_HUMAN AALREKTSLSANNATLEKQLIELTRTNELLKSKFSENGNQKNLRILSLELMKLRNKRETK B4E114_HUMAN B4E114_HUMAN AALREKTSLSANNATLEKQLIELTRTNELLKSKFSENGNQKNLRILSLELMKLRNKRETK Q32N02_HUMAN Q32N02_HUMAN AALREKTSLSANNATLEKQLIELTRTNELLKSKFSENGNQKNLRILSLELMKLRNKRETK B4DZK6_HUMAN B4DZK6_HUMAN ---------------LEKQLIELTRTNELLKSKFSENGNQKNLRILSLELMKLRNKRETK A8K3G2_HUMAN A8K3G2_HUMAN AALREKTSLSANNATLEKQLIELTRTNELLKSKFSENGNQKNLRILSLELMKLRNKRETK HMMR_HUMAN HMMR_HUMAN AALREKTSLSANNATLEKQLIELTRTNELLKSKFSENGNQKNLRILSLELMKLRNKRETK Q8VDR2_MOUSE Q8VDR2_MOUSE AAVREKTSLSASNASLEKRLTELTRANELLKSKFSEDGHQKNMRALSLELMKLRNKRETK HMMR_MOUSE HMMR_MOUSE AAVREKTSLSASNASLEKRLTELTRANELLKAKFSEDGHQKNMRALSLELMKLRNKRETK Q3UPW7_MOUSE Q3UPW7_MOUSE AAVREKTSLSASNASLEKRLTELTRANELLKAKFSEDGHQKNMRALSLELMKLRNKRETK Q5NC88_MOUSE Q5NC88_MOUSE AAVREKTSLSASNASLEKRLTELTRANELLKAKFSEDGHQKNMRALSLELMKLRNKRETK HMMR_RAT HMMR_RAT ------------------------------------------------------------ Q9WUF7_RAT Q9WUF7_RAT APVTEKPSLSANNASLEKRLTELTRANELLKSKFSEDAHQKNMRTLSLELMKLRNKRETK MATCH CONSENSUS A???EK?SLSA?NA?LEK?L?ELTR?NELLK?KFSE?G?QKN?R?LSLELMKLRNKRETK

Q4R499_MACFA Q4R499_MACFA ------------------------------------------------------------ Q6NSC0_HUMAN Q6NSC0_HUMAN MRGMMAKQEGMEMKLQVTQRSLEESQGKIAQLEGKLVSIEKEKIDEKSETEKLLEYIEEI Q05DM0_HUMAN Q05DM0_HUMAN MRGMMAKQEGMEMKLQVTQRSLEESQGKIAQLEGKLVSIEKEEIDEKSETEKLLEYIEEI Q6PG44_HUMAN Q6PG44_HUMAN MRGMMAKQEGMEMKLQVTQRSLEESQGKIAQLEGKLVSIEKEKIDEKSETEKLLEYIEEI B4E114_HUMAN B4E114_HUMAN MRGMMAKQEGMEMKLQVTQRSLEESQGKIAQLEGKLVSIEKEKIDEKSETEKLLEYIEEI Q32N02_HUMAN Q32N02_HUMAN MRGMMAKQEGMEMKLQVTQRSLEESQGKIAQLEGKLVSIEKEKIDEKSETEKLLEYIEEI B4DZK6_HUMAN B4DZK6_HUMAN MRGMMAKQEGMEMKLQVTQRSLEESQGKIAQLEGKLVSIEKEKIDEKSETEKLLEYIEEI A8K3G2_HUMAN A8K3G2_HUMAN MRGMMAKQEGMEMKLQVTQRSLEESQGKIAQLEGKLVSIEKEKIDEKSETEKLLEYIEEI HMMR_HUMAN HMMR_HUMAN MRGMMAKQEGMEMKLQVTQRSLEESQGKIAQLEGKLVSIEKEKIDEKSETEKLLEYIEEI Q8VDR2_MOUSE Q8VDR2_MOUSE MRSMMVKQEGMELKLQATQKDLTESKGKIVQLEGKLVSIEKEKIDEKCETEKLLEYIQEI HMMR_MOUSE HMMR_MOUSE MRSMMVKQEGMELKLQATQKDLTESKGKIVQLEGKLVSIEKEKIDEKCETEKLLEYIQEI Q3UPW7_MOUSE Q3UPW7_MOUSE MRSMMVKQEGMELKLQATQKDLTESKGKIVQLEGKLVSIEKEKIDEKCETEKLLEYIQEI Q5NC88_MOUSE Q5NC88_MOUSE MRSMMVKQEGMELKLQATQKDLTESKGKIVQLEGKLVSIEKEKIDEKCETEKLLEYIQEI HMMR_RAT HMMR_RAT ---------------------------------GWL---------EKSETEKLLEYIEEI Q9WUF7_RAT Q9WUF7_RAT MRSMMAKQEGMELKLQATQKDLIESKGKIVQLEGKLVSIEKEKIDEKSETEKLLEYIEEI MATCH CONSENSUS MR?MM?KQEGME?KLQ?TQ??L?ES?GKI?QLEGKLVSIEKEKIDEK?ETEKLLEYI?EI

Q4R499_MACFA Q4R499_MACFA ------------------------------------------------------------ Q6NSC0_HUMAN Q6NSC0_HUMAN SCASDQVEKYKLDIAQLEENLKEKNDEILSLKQSLEENIVILSKQVEDLNVKCQLLEKEK Q05DM0_HUMAN Q05DM0_HUMAN SCASDQVEKYKLDIAQLEENLKEKNDEILSLKQSLEENIVILSKQVEDLNVKCQLLEKEK Q6PG44_HUMAN Q6PG44_HUMAN SCASDQVEKYKLDIAQLEENLKEKNDEILSLKQSLEENIVILSKQVEDLNVKCQLLEKEK B4E114_HUMAN B4E114_HUMAN SCASDQVEKYKLDIAQLEENLKEKNDEILSLKQSLEENIVILSKQVEDLNVKCQLLEKEK Q32N02_HUMAN Q32N02_HUMAN SCASDQVEKYKLDIAQLEENLKEKNDEILSLKQSLEENIVILSKQVEDLNVKCQLLEKEK B4DZK6_HUMAN B4DZK6_HUMAN SCASDQVEKYKLDIAQLEENLKEKNDEILSLKQSLEENIVILSKQVEDLNVKCQLLEKEK A8K3G2_HUMAN A8K3G2_HUMAN SCASDQVEKYKLDIAQLEENLKEKNDEILSLKQSLEENIVILSKQVEDLNVKCQLLEKEK HMMR_HUMAN HMMR_HUMAN SCASDQVEKYKLDIAQLEENLKEKNDEILSLKQSLEENIVILSKQVEDLNVKCQLLEKEK Q8VDR2_MOUSE Q8VDR2_MOUSE SCASDQVEKCKVDIAQLEEDLKEKDREILSLKQSLEENIT-FSKQIEDLTVKCQLLETER HMMR_MOUSE HMMR_MOUSE SCASDQVEKCKVDIAQLEEDLKEKDREILSLKQSLEENIT-FSKQIEDLTVKCQLLETER Q3UPW7_MOUSE Q3UPW7_MOUSE SCASDQVEKCKVDIAQLEEDLKEKDREILSLKQSLEENIT-FSKQIEDLTVKCQLLETER Q5NC88_MOUSE Q5NC88_MOUSE SCASDQVEKCKVDIAQLEEDLKEKDREILSLKQSLEENIT-FSKQIEDLTVKCQLLETER HMMR_RAT HMMR_RAT SCASDQVEKYKLDIAQLEEDLKEKDREILCLKQSLEEKVS-FSKQIEDLTVKCQLLEAER Q9WUF7_RAT Q9WUF7_RAT SCASDQVEKYKLDIAQLEEDLKEKDREILCLKQSLEEKVS-FSKQIEDLTVKCQLLEAER MATCH CONSENSUS SCASDQVEK?K?DIAQLEE?LKEK??EILSLKQSLEENI???SKQ?EDL?VKCQLLE?E?

Q4R499_MACFA Q4R499_MACFA -----------------MQNLKQKLILEQQECEKLQQKQLQVDSLLQQEKELSASLHQKL Q6NSC0_HUMAN Q6NSC0_HUMAN EDHVNRNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQIDSLLQQEKELSSSLHQKL Q05DM0_HUMAN Q05DM0_HUMAN EDHVNRNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQIDSLLQQEKELSSSLHQKL Q6PG44_HUMAN Q6PG44_HUMAN EDHVNRNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQIDSLLQQEKELSSSLHQKL B4E114_HUMAN B4E114_HUMAN EDHVNRNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQIDSLLQQEKELSSSLHQKL Q32N02_HUMAN Q32N02_HUMAN EDHVNRNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQIDSLLQQEKELSSSLHQKL B4DZK6_HUMAN B4DZK6_HUMAN EDHVNRNREHNENLNAEMQNLKQKFILEQQEHEKLQQKELQIDSLLQQEKELSSSLHQKL A8K3G2_HUMAN A8K3G2_HUMAN EDHVNRNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQIDSLLQQEKELSSSLHQKL HMMR_HUMAN HMMR_HUMAN EDHVNRNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQIDSLLQQEKELSSSLHQKL Q8VDR2_MOUSE Q8VDR2_MOUSE DNLVSKDRERAETLSAEMQILTERLALERQEYEKLQQKELQSQSLLQQEKELSARLQQQL HMMR_MOUSE HMMR_MOUSE DNLVSKDRERAETLSAEMQILTERLALERQEYEKLQQKELQSQSLLQQEKELSARLQQQL Q3UPW7_MOUSE Q3UPW7_MOUSE DNLVSKDRERAETLSAEMQILTERLALERQEYEKLQQKELQSQSLLQQEKELSARLQQQL Q5NC88_MOUSE Q5NC88_MOUSE DNLVSKDRERAETLSAEMQILTERLALERQEYEKLQQKELQSQSLLQQEKELSARLQQQL HMMR_RAT HMMR_RAT DDLVSKDRERAESLSAEMQVLTEKLLLERQEYEKLQQNELQSQSLLQQEKELSAHLQQQL Q9WUF7_RAT Q9WUF7_RAT DDLVSKDRERAESLSAEMQVLTEKLLLERQEYEKLQQNELQSQSLLQQEKELSAHLQQQL MATCH ** *.::: **:** *****::** :**********: *:*:* CONSENSUS ???V???RE??E?L?AEMQ?L?????LE?QE?EKLQQKELQ??SLLQQEKELS??L?Q?L

Q4R499_MACFA Q4R499_MACFA CSFQEEVVKEKNLFEEELKQALDELDKLQQKEEQAERLVKQLEEEAKSRAEELKLLEGKL Q6NSC0_HUMAN Q6NSC0_HUMAN CSFQEEMAKEKNLFEEELKQTLDELDKLQQKEEQAERLVKQLEEEAKSRAEELKLLEEKL Q05DM0_HUMAN Q05DM0_HUMAN CSFQEEMVKEKNLFEEELKQTLDELDKLQQKEEQAERLVKQLEEEAKSRAEELKLLEEKL Q6PG44_HUMAN Q6PG44_HUMAN CSFQEEMVKEKNLFEEELKQTLDELDKLQQKEEQAERLVKQLEEEAKSRAEELKLLEEKL B4E114_HUMAN B4E114_HUMAN CSFQEEMAKEKNLFEEELKQTLDELDKLQQKEEQAERLVKQLEEEAKSRAEELKLLEEKL Q32N02_HUMAN Q32N02_HUMAN CSFQEEMAKEKNLFEEELKQTLDELDKLQQKEEQAERLVKQLEEEAKSRAEELKLLEEKL B4DZK6_HUMAN B4DZK6_HUMAN CSFQEEMVKEKNLFEEELKQTLDELDKLQQKEEQAERLVKQLEEEAKSRAEELKLLEEKL A8K3G2_HUMAN A8K3G2_HUMAN CSFQEEMVKEKNLFEEELKQTLDELDKLQQKEEQAERLVKQLEEEAKSRAEELKLLEEKL HMMR_HUMAN HMMR_HUMAN CSFQEEMVKEKNLFEEELKQTLDELDKLQQKEEQAERLVKQLEEEAKSRAEELKLLEEKL Q8VDR2_MOUSE Q8VDR2_MOUSE CSFQEEMTSEKNVFKEELKLALAELDAVQQKEEQSERLVKQLEEETKSTAEQLKRLDNLL HMMR_MOUSE HMMR_MOUSE CSFQEEMTSEKNVFKEELKLALAELDAVQQKEEQSERLVKQLEEERKSTAEQLTRLDNLL Q3UPW7_MOUSE Q3UPW7_MOUSE CSFQEEMTSEKNVFKEELKLALAELDAVQQKEEQSERLVKQLEEETKSTAEQLTRLDNLL Q5NC88_MOUSE Q5NC88_MOUSE CSFQEEMTSEKNVFKEELKLALAELDAVQQKEEQSERLVKQLEEETKSTAEQLTRLDNLL HMMR_RAT HMMR_RAT CSFQEEMTSERNVFKEQLKLALDELDAVQQKEEQSEKLVKQLEEETKSTAEQLRRLDDLL Q9WUF7_RAT Q9WUF7_RAT CSFQEEMTSERNVFKEQLKLALDELDAVQQKKEQSEKLVKQLEEETKSTAEQLRRLDDLL MATCH ******:..*:*:*:*:** :* *** :***:**:*:******** ** **:* *: * CONSENSUS CSFQEEM??EKN?F?EELK??L?ELD??QQKEEQ?ERLVKQLEEE?KS?AE?L??L???L

Q4R499_MACFA Q4R499_MACFA KGKEAELEKSSAAHNQATLLL--------------------------------------- Q6NSC0_HUMAN Q6NSC0_HUMAN KGKEAELEKSSAAHTQATLLL--------------------------------------- Q05DM0_HUMAN Q05DM0_HUMAN KGKEAELEKSSAAHTQATLLL--------------------------------------- Q6PG44_HUMAN Q6PG44_HUMAN KGKEAELEKSSAAHTQATLLL--------------------------------------- B4E114_HUMAN B4E114_HUMAN KGKEAELEKSSAAHTQATLLL--------------------------------------- Q32N02_HUMAN Q32N02_HUMAN KGKEAELEKSSAAHTQATLLL--------------------------------------- B4DZK6_HUMAN B4DZK6_HUMAN KGKEAELEKSSAAHTQATLLL--------------------------------------- A8K3G2_HUMAN A8K3G2_HUMAN KGKEAELEKSSAAHTQATLLL--------------------------------------- HMMR_HUMAN HMMR_HUMAN KGKEAELEKSSAAHTQATLLL--------------------------------------- Q8VDR2_MOUSE Q8VDR2_MOUSE REKEVELEKHIAAHAQAILIAQEKYNDTAQSLRDVTAQLESEQEKYNDTAQSLRDVTAQL HMMR_MOUSE HMMR_MOUSE REKEVELEKHIAAHAQAILIA--------------------------------------- Q3UPW7_MOUSE Q3UPW7_MOUSE REKEVELEKHIAAHAQAILIA--------------------------------------- Q5NC88_MOUSE Q5NC88_MOUSE REKEVELEKHIAAHAQAILIA--------------------------------------- HMMR_RAT HMMR_RAT REKEIELEKRTAAHAQATVIA--------------------------------------- Q9WUF7_RAT Q9WUF7_RAT REKEIELEKRTAAHAQATVIA--------------------------------------- MATCH : ** **** *** ** :: CONSENSUS ??KE?ELEK??AAH?QA?L?????????????????????????????????????????

Q4R499_MACFA Q4R499_MACFA ------------------------------------------------------------ Q6NSC0_HUMAN Q6NSC0_HUMAN ------------------------------------------------------------ Q05DM0_HUMAN Q05DM0_HUMAN ------------------------------------------------------------ Q6PG44_HUMAN Q6PG44_HUMAN ------------------------------------------------------------ B4E114_HUMAN B4E114_HUMAN ------------------------------------------------------------ Q32N02_HUMAN Q32N02_HUMAN ------------------------------------------------------------ B4DZK6_HUMAN B4DZK6_HUMAN ------------------------------------------------------------ A8K3G2_HUMAN A8K3G2_HUMAN ------------------------------------------------------------ HMMR_HUMAN HMMR_HUMAN ------------------------------------------------------------ Q8VDR2_MOUSE Q8VDR2_MOUSE ESVQEKYNDTAQSLRDVTAQLESEQEKYNDTAQSLRDVTAQLESEQKKYNDTAQSLRDVT HMMR_MOUSE HMMR_MOUSE ---QEKYNDTAQSLRDVTAQLESVQEKYNDTAQSLRDVTAQLESEQEKYNDTAQSLRDVT Q3UPW7_MOUSE Q3UPW7_MOUSE ---QEKYNDTAQSLRDVTAQLESVQEKYNDTAQSLRDVTAQLESEQEKYNDTAQSLRDVT Q5NC88_MOUSE Q5NC88_MOUSE ---QEKYNDTAQSLRDVTAQLESVQEKYNDTAQSLRDVTAQLESEQEKYNDTAQSLRDVT HMMR_RAT HMMR_RAT ------------------------------------------------------------ Q9WUF7_RAT Q9WUF7_RAT ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

Q4R499_MACFA Q4R499_MACFA ---------------------------QEKYNSTVQSLEDVTAQFESYKALTASEIEDLK Q6NSC0_HUMAN Q6NSC0_HUMAN ---------------------------QEKYDSMVQSLEDVTAQFESYKALTASEIEDLK Q05DM0_HUMAN Q05DM0_HUMAN ---------------------------QEKYDSMVQSLEDVTAQFESYKALTASEIEDLK Q6PG44_HUMAN Q6PG44_HUMAN ---------------------------QEKYDSMVQSLEDVTAQFESYKALTASEIEDLK B4E114_HUMAN B4E114_HUMAN ---------------------------QEKYDSMVQSLEDVTAQFESYKALTASEIEDLK Q32N02_HUMAN Q32N02_HUMAN ---------------------------QEKYDSMVQSLEDVTAQFESYKALTASEIEDLK B4DZK6_HUMAN B4DZK6_HUMAN ---------------------------QEKYDSMVQSLEDVTAQFESYKALTASEIEDLK A8K3G2_HUMAN A8K3G2_HUMAN ---------------------------QEKYDSMVQSLEDVTAQFESYKALTASEIEDLK HMMR_HUMAN HMMR_HUMAN ---------------------------QEKYDSMVQSLEDVTAQFESYKALTASEIEDLK Q8VDR2_MOUSE Q8VDR2_MOUSE AQLESEQEKYNDTAQSLRDVTAQLESVQEKYNDTAQSLRDVTAQLESYKSSTLKEIEDLK HMMR_MOUSE HMMR_MOUSE AQLESEQEKYNDTAQSLRDVTAQLESVQEKYNDTAQSLRDVSAQLESYKSSTLKEIEDLK Q3UPW7_MOUSE Q3UPW7_MOUSE AQLESEQEKYNDTAQSLRDVTAQLESVQEKYNDTAQSLRDVTAQLESYKSSTLKEIEDLK Q5NC88_MOUSE Q5NC88_MOUSE AQLESEQEKYNDTAQSLRDVTAQLESVQEKYNDTAQSLRDVTAQLESYKSSTLKEIEDLK HMMR_RAT HMMR_RAT ---------------------------QEKYSDTAQTLRDVTAQLESYKSSTLKEIEDLK Q9WUF7_RAT Q9WUF7_RAT ---------------------------QEKYSDTAQTLRDVTAQLESYKSSTLKEIEDLK MATCH ****.. .*:*.**:**:****: * .****** CONSENSUS ???????????????????????????QEKY????QSL?DVTAQ?ESYK??T??EIEDLK

Q4R499_MACFA Q4R499_MACFA LENSSLQETVAKAGKSAEDVQHQILATESSNQEYARMLLDLQTKSALKETEIKEITVSFL Q6NSC0_HUMAN Q6NSC0_HUMAN LENSSLQEKVAKAGKNAEDVQHQILATESSNQEYVRMLLDLQTKSALKETEIKEITVSFL Q05DM0_HUMAN Q05DM0_HUMAN LENSSLQEKAAKAGKNAEDVQHQILATESSNQEYVRMLLDLQTKSAKKKKKKK------- Q6PG44_HUMAN Q6PG44_HUMAN LENSSLQEKAAKAGKNAEDVQHQILATESSNQEYVRMLLDLQTKSALKETEIKEITVSFL B4E114_HUMAN B4E114_HUMAN LENSSLQEKVAKAGKNAEDVQHQILATESSNQEYVRMLLDLQTKSALKETEIKEITVSFL Q32N02_HUMAN Q32N02_HUMAN LENSSLQEKVAKAGKNAEDVQHQILATESSNQEYVRMLLDLQTKSALKETEIKEITVSFL B4DZK6_HUMAN B4DZK6_HUMAN LENSSLQEKAAKAGKNAEDVQHQILATESSNQEYVRMLLDLQTKSALKETEIKEITVSFL A8K3G2_HUMAN A8K3G2_HUMAN LENSSLQEKAAKAGKNAEDVQHQILATESSNQEYVRMLLDLQTKSALKETEIKEITVSFL HMMR_HUMAN HMMR_HUMAN LENSSLQEKAAKAGKNAEDVQHQILATESSNQEYVRMLLDLQTKSALKETEIKEITVSFL Q8VDR2_MOUSE Q8VDR2_MOUSE LENLTLQEKVAMAEKSVEDVQQQILTAESTNQEYARMVQDLQNRSTLKEEEIKEITSSFL HMMR_MOUSE HMMR_MOUSE LENLTLQEKVAMAEKSVEDVQQQILTAESTNQEYARMVQDLQNRSTLKEEEIKEITSSFL Q3UPW7_MOUSE Q3UPW7_MOUSE LENLTLQEKVAMAEKSVEDVQQQILTAESTNQEYARMVQDLQNRSTLKEEEIKEITSSFL Q5NC88_MOUSE Q5NC88_MOUSE LENLTLQEKVAMAEKSVEDVQQQILTAESTNQEYARMVQDLQNRSTLKEEEIKEITSSFL HMMR_RAT HMMR_RAT LENLTLQEKVAMAEKRVEDVQQQILTAESTNQEYAKVVQDLQNSSTLKEAEIKEITSSYL Q9WUF7_RAT Q9WUF7_RAT LENLTLQEKVAMAEKRVEDVQQQILTAESTNQEYAKVVQDLQNSSTLKEAEIKEITSSYL MATCH *** :***..* * * .****:***::**:****.::: ***. *: *: : * CONSENSUS LEN??LQEK?A?A?K??EDVQ?QIL??ES?NQEY?RM??DLQ??S?LKE?EIKEIT?SFL

Q4R499_MACFA Q4R499_MACFA QKITDLQNQLKQQEEDFRKQLEDEEGRKAGKENTTAELTEEINKWRLLYEELYNKTKPFQ Q6NSC0_HUMAN Q6NSC0_HUMAN QKITDLQNQLKQQEEDFRKQLEDEKKK--------------------------------- Q05DM0_HUMAN Q05DM0_HUMAN ------------------------------------------------------------ Q6PG44_HUMAN Q6PG44_HUMAN QKITDLQNQLKQQEEDFRKQLEDEEGRKAEKENTTAELTEEINKWRLLYEELYNKTKPFQ B4E114_HUMAN B4E114_HUMAN QKITDLQNQLKQQEEDFRKQLEDEEGRKAEKENTTAELTEEINKWRLLYEELYNKTKPFQ Q32N02_HUMAN Q32N02_HUMAN QKITDLQNQLKQQEEDFRKQLEDEEGRKAEKENTTAELTEEINKWRLLYEELYNKTKPFQ B4DZK6_HUMAN B4DZK6_HUMAN QKITDLQNQLKQQEEDFRKQLEDEEGRKAEKENTTAELTEEINKWRLLYEELYNKTKPFQ A8K3G2_HUMAN A8K3G2_HUMAN QKITDLQNQLKQREEDFRKQLEDEEGRKAEKENTTAELTEEINKWRLLYEELYNKTKPFQ HMMR_HUMAN HMMR_HUMAN QKITDLQNQLKQQEEDFRKQLEDEEGRKAEKENTTAELTEEINKWRLLYEELYNKTKPFQ Q8VDR2_MOUSE Q8VDR2_MOUSE EKITDLKNQLRQQDEDFRKQLEEKGKRTAEKENVMTELTMEINKWRLLYEELYEKTKPFQ HMMR_MOUSE HMMR_MOUSE EKITDLKNQLRQQDEDFRKQLEEKGKRTAEKENVMTELTMEINKWRLLYEELYEKTKPFQ Q3UPW7_MOUSE Q3UPW7_MOUSE EKITDLKNQLRQQDEDFRKQLEEKGKRTA------------------------------- Q5NC88_MOUSE Q5NC88_MOUSE EKITDLKNQLRQQDEDFRKQLEEKGKRTAEKENVMTELTMEINKWRLLYEELYEKTKPFQ HMMR_RAT HMMR_RAT EKITDLQNQLRQQNEDFRKQLEEEGAKMTEKETAVTELTMEINKWRLLYEELYDKTKPFQ Q9WUF7_RAT Q9WUF7_RAT EKITDLQNQLRQQNEDFRKQLEEEGAKMTEKETAVTELTMEINKWRLLYEELFDKTKPFQ MATCH CONSENSUS ?KITDL?NQL?QQ?EDFRKQLE????????KE????ELT?EINKWRLLYEEL??KTKPFQ

Q4R499_MACFA Q4R499_MACFA LQLDAFEAEKQALLNEHGAAQEQLNKIRDSYAKLLGHQNLKQKIKHVVKLKDENSQLKSE Q6NSC0_HUMAN Q6NSC0_HUMAN ------------------------------------------------------------ Q05DM0_HUMAN Q05DM0_HUMAN ------------------------------------------------------------ Q6PG44_HUMAN Q6PG44_HUMAN LQLDAFEVEKQALLNEHGAAQEQLNKIK-------------------------------- B4E114_HUMAN B4E114_HUMAN LQLDAFEVEKQALLNEHGAAQEQLNKIRDSYAKLLGHQNLKQKIKHVVKLKDENSQLKSE Q32N02_HUMAN Q32N02_HUMAN LQLDAFEVEKQALLNEHGAAQEQLNKIRDSYAKLLGHQNLKQKIKHVVKLKDENSQLKSE B4DZK6_HUMAN B4DZK6_HUMAN LQLDAFEVEKQALLNEHGAAQEQLNKIRDSYAKLLGHQNLKQKIKHVVKLKDENSQLKSE A8K3G2_HUMAN A8K3G2_HUMAN LQLDAFEVEKQALLNEHGAAQEQLNKIRDSYAKLLGHQNLKQKIKHVVKLKDENSQLKSE HMMR_HUMAN HMMR_HUMAN LQLDAFEVEKQALLNEHGAAQEQLNKIRDSYAKLLGHQNLKQKIKHVVKLKDENSQLKSE Q8VDR2_MOUSE Q8VDR2_MOUSE QQLDAFEAEKQALLNEHGATQEQLNKIRDSYAQLLGHQNLKQKIKHVVKLKDENSQLKSE HMMR_MOUSE HMMR_MOUSE QQLDAFEAEKQALLNEHGATQEQLNKIRDSYAQLLGHQNLKQKIKHVVKLKDENSQLKSE Q3UPW7_MOUSE Q3UPW7_MOUSE ------------------------------------------------------------ Q5NC88_MOUSE Q5NC88_MOUSE QQLDAFEAEKQALLNEHGATQEQLNKIRDSYAQLLGHQNLKQKIKHVVKLKDENSQLKSE HMMR_RAT HMMR_RAT QQLDAFEAEKQALLNEHGATQEQLSKIRDSYAQLLGHQNLKQKIKHVVKLKDENSQLKSE Q9WUF7_RAT Q9WUF7_RAT QQLDAFEAEKQALLNEHGATQEQLSKIRDSYAQLLGHQNLKQKIKHVVKLKDENSQLKSE MATCH CONSENSUS ?QLDAFE?EKQALLNEHGA?QEQL?KI?????????????????????????????????

Q4R499_MACFA Q4R499_MACFA VSKLRCQLAKKKQSETKLQEELNKVLGIKHFDPSKAFHHESKENFALKTPLKEGSTNCY- Q6NSC0_HUMAN Q6NSC0_HUMAN ---------KKKKKK--------------------------------------------- Q05DM0_HUMAN Q05DM0_HUMAN ------------------------------------------------------------ Q6PG44_HUMAN Q6PG44_HUMAN ---------KKKKKK--------------------------------------------- B4E114_HUMAN B4E114_HUMAN VSKLRCQLAKKKQSETKLQEELNKVLGIKHFDPSKAFHHESKENFALKTPLKEGNTNCYR Q32N02_HUMAN Q32N02_HUMAN VSKLRCQLAKKKQSETKLQEELNKVLGIKHFDPSKAFHHESKENFALKTPLKEGNTNCYR B4DZK6_HUMAN B4DZK6_HUMAN VSKLRCQLAKKKQSETKLQEELNKVLGIKHFDPSKAFHHESKENFALKTPLKEGNTNCYR A8K3G2_HUMAN A8K3G2_HUMAN VSKLRCQLAKKKQSETKLQEELNKVLGIKHFDPSKAFHHESKENFALKTPLKEGNTNCYR HMMR_HUMAN HMMR_HUMAN VSKLRCQLAKKKQSETKLQEELNKVLGIKHFDPSKAFHHESKENFALKTPLKEGNTNCYR Q8VDR2_MOUSE Q8VDR2_MOUSE VSKLRSQLVKRKQNELRLQGELDKALGIRHFDPSKAFCHASKENF---TPLKEGNPNCC- HMMR_MOUSE HMMR_MOUSE VSKLRSQLVKRKQNELRLQGELDKALGIRHFDPSKAFCHASKENF---TPLKEGNPNCC- Q3UPW7_MOUSE Q3UPW7_MOUSE ------------------------------------------------------------ Q5NC88_MOUSE Q5NC88_MOUSE VSKLRSQLVKRKQNELRLQGELDKALGIRHFDPSKAFCHASKENF---TPLKEGNPNCC- HMMR_RAT HMMR_RAT VSKLRSQLAKRKQNELRLQGELDKALGIRHFDPPKAFCHESKENVTLKTPLKEGNPNCC- Q9WUF7_RAT Q9WUF7_RAT VSKLRSQLAKRKQNELRLQGELDKALGIRHFDPSKAFCHESKENVTLKTPLKEGNPNCC- MATCH CONSENSUS ?????????K?K????????????????????????????????????????????????

Q4R499_MACFA Q4R499_MACFA ---------- Q6NSC0_HUMAN Q6NSC0_HUMAN ---------- Q05DM0_HUMAN Q05DM0_HUMAN ---------- Q6PG44_HUMAN Q6PG44_HUMAN ---------- B4E114_HUMAN B4E114_HUMAN APMECQESWK Q32N02_HUMAN Q32N02_HUMAN APMECQESWK B4DZK6_HUMAN B4DZK6_HUMAN APMECQESWK A8K3G2_HUMAN A8K3G2_HUMAN APMECQESWK HMMR_HUMAN HMMR_HUMAN APMECQESWK Q8VDR2_MOUSE Q8VDR2_MOUSE ---------- HMMR_MOUSE HMMR_MOUSE ---------- Q3UPW7_MOUSE Q3UPW7_MOUSE ---------- Q5NC88_MOUSE Q5NC88_MOUSE ---------- HMMR_RAT HMMR_RAT ---------- Q9WUF7_RAT Q9WUF7_RAT ---------- MATCH CONSENSUS ??????????


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