Alignment of the gene Family HBG045631 of HOVERGEN

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Threshold: 50% 80% 100%
Size: Bigger Smaller Normal
Isoforms are ON
A5PL83_DANRE A5PL83_DANRE -----------------------------------MAAA--------------------- Q5RHD1_DANRE Q5RHD1_DANRE -----------------------------------MAAA--------------------- Q08D35_XENTR Q08D35_XENTR -----------------------------------MAGAA-------------------- A4D1S9_HUMAN A4D1S9_HUMAN ------------------------------------------------------------ JHD1D_HUMAN JHD1D_HUMAN -----------------------------------MAGAAAAVAAGAAAGAAAAAVSVAA A6H6E5_MOUSE A6H6E5_MOUSE ------------------------------------------------------------ JHD1D_MOUSE JHD1D_MOUSE -----------------------------------MAGAAAAVAAGAAAGAAAAAGSVSA B9EKK1_MOUSE B9EKK1_MOUSE -----------------------------------MALV--------------------- B6D5P9_PERLE B6D5P9_PERLE ------------------------------------------------------------ B6D5P7_PERPL B6D5P7_PERPL ------------------------------------------------------------ B6D5P8_PERMA B6D5P8_PERMA ------------------------------------------------------------ B6D5Q0_PERER B6D5Q0_PERER ------------------------------------------------------------ B6D5Q1_PERCA B6D5Q1_PERCA ------------------------------------------------------------ Q28G38_XENTR Q28G38_XENTR -----------------------------------MASV--------------------- Q7T0U8_XENLA Q7T0U8_XENLA -----------------------------------MASV--------------------- Q5JPS0_HUMAN Q5JPS0_HUMAN -----------------------------------MASV--------------------- Q5JPS3_HUMAN Q5JPS3_HUMAN ------------------------------------------------------------ PHF8_HUMAN PHF8_HUMAN NRSRAIVQRGRVLPPPAPLDTTNLAGRRTLQGRAKMASV--------------------- B7Z911_HUMAN B7Z911_HUMAN -----------------------------------MASV--------------------- Q5JPS2_HUMAN Q5JPS2_HUMAN ------------------------------------------------------------ Q5JPR9_HUMAN Q5JPR9_HUMAN -----------------------------------MASV--------------------- A2ABV1_MOUSE A2ABV1_MOUSE -----------------------------------MASV--------------------- Q3UZ32_MOUSE Q3UZ32_MOUSE -----------------------------------MASV--------------------- A2ABV3_MOUSE A2ABV3_MOUSE -----------------------------------MASV--------------------- A2ABV2_MOUSE A2ABV2_MOUSE -----------------------------------MASV--------------------- A2ABU8_MOUSE A2ABU8_MOUSE -----------------------------------MASV--------------------- PHF8_MOUSE PHF8_MOUSE -----------------------------------MASV--------------------- PHF2_HUMAN PHF2_HUMAN -----------------------------------MATV--------------------- PHF2_MOUSE PHF2_MOUSE -----------------------------------MATV--------------------- Q6A023_MOUSE Q6A023_MOUSE ------------------------------------------------------------ Q4STN5_TETNG Q4STN5_TETNG ----------------------------------NMATV--------------------- Q6P949_DANRE Q6P949_DANRE -----------------------------------MATV--------------------- MATCH CONSENSUS ????????????????????????????????????????????????????????????

A5PL83_DANRE A5PL83_DANRE -----------PLYCVCRQPYDVNRFMIECDICKDWFHGSCVQVVEHHAADIDVYHCPNC Q5RHD1_DANRE Q5RHD1_DANRE -----------PLYCVCRQPYDVNRFMIECDICKDWFHGSCVQVVEHHAADIDVYHCPNC Q08D35_XENTR Q08D35_XENTR -----------PVYCVCRQPYDVSRFMIECDICKDWFHSSCVKVEEHQAADIDLYHCPNC A4D1S9_HUMAN A4D1S9_HUMAN --------------------------MIECDICKDWFHGSCVGVEEHHAVDIDLYHCPNC JHD1D_HUMAN JHD1D_HUMAN PGRASAPPPPPPVYCVCRQPYDVNRFMIECDICKDWFHGSCVGVEEHHAVDIDLYHCPNC A6H6E5_MOUSE A6H6E5_MOUSE --------------------------MIECDVCKDWFHGSCVGVEEHHAVDIDLYHCPDC JHD1D_MOUSE JHD1D_MOUSE PGRASAPPPPPPVYCVCRQPYDVNRFMIECDVCKDWFHGSCVGVEEHHAVDIDLYHCPDC B9EKK1_MOUSE B9EKK1_MOUSE -----------PVYCLCRQPYNVNHFMIECGLCQDWFHGSCVGIEEENAVDIDIYHCPDC B6D5P9_PERLE B6D5P9_PERLE -----------------------KSFMIECDLCQDWFHGGCVRIEEKIADDIDIYHCPNC B6D5P7_PERPL B6D5P7_PERPL -----------------------KRFMIECDLCQDWFHGGCVCIEEKKADDIDIYHCPNC B6D5P8_PERMA B6D5P8_PERMA -----------------------KRFMIECDLCQDWFHGGCVCIEEKKADDIDIYHCPNC B6D5Q0_PERER B6D5Q0_PERER -----------------------KDFMIQCDLCQDWFHGGCIGIEEEKADDIDIYHCPNC B6D5Q1_PERCA B6D5Q1_PERCA -----------------------NSFMIQCDLCQDWFHGGCVGIEEEKAEEIDIYHCPNC Q28G38_XENTR Q28G38_XENTR -----------PVYCLCRLPYDVTRFMIECDVCQDWFHGSCVGVEEEKASEIDLYHCPNC Q7T0U8_XENLA Q7T0U8_XENLA -----------PVYCLCCLPYDVTRFMIECDVCQDWFHGSCVGVEEEKASEIDLYHCPNC Q5JPS0_HUMAN Q5JPS0_HUMAN -----------PVYCLCRLPYDVTRFMIECDMCQDWFHGSCVGVEEEKAADIDLYHCPNC Q5JPS3_HUMAN Q5JPS3_HUMAN ------------------------------------------------------------ PHF8_HUMAN PHF8_HUMAN -----------PVYCLCRLPYDVTRFMIECDMCQDWFHGSCVGVEEEKAADIDLYHCPNC B7Z911_HUMAN B7Z911_HUMAN -----------PVYCLCRLPYDVTRFMIECDMCQDWFHGSCVGVEEEKAADIDLYHCPNC Q5JPS2_HUMAN Q5JPS2_HUMAN ------------------------------------------------------------ Q5JPR9_HUMAN Q5JPR9_HUMAN -----------PVYCLCRLPYDVTRFMIECDMCQDWFHGSCVGVEEEKAADIDLYHCPNC A2ABV1_MOUSE A2ABV1_MOUSE -----------PVYCLCRLPYDVTRFMIECDMCQDWFHGSCVGVEEEKAADIDLYHCPNC Q3UZ32_MOUSE Q3UZ32_MOUSE -----------PVYCLCRLPYDVTRFMIECDMCQDWFHGSCVGVEEEKAADIDLYHCPNC A2ABV3_MOUSE A2ABV3_MOUSE -----------PVYCLCRLPYDVTRFMIECDMCQDWFHGSCVGVEEEKAADIDLYHCPNC A2ABV2_MOUSE A2ABV2_MOUSE -----------PVYCLCRLPYDVTRFMIECDMCQDWFHGSCVGVEEEKAADIDLYHCPNC A2ABU8_MOUSE A2ABU8_MOUSE -----------PVYCLCRLPYDVTRFMIECDMCQDWFHGSCVGVEEEKAADIDLYHCPNC PHF8_MOUSE PHF8_MOUSE -----------PVYCLCRLPYDVTRFMIECDMCQDWFHGSCVGVEEEKAADIDLYHCPNC PHF2_HUMAN PHF2_HUMAN -----------PVYCVCRLPYDVTRFMIECDACKDWFHGSCVGVEEEEAPDIDIYHCPNC PHF2_MOUSE PHF2_MOUSE -----------PVYCVCRLPYDVTRFMIECDACKDWFHGSCVGVEEEEAPDIDIYHCPNC Q6A023_MOUSE Q6A023_MOUSE ------------------------------------------------------------ Q4STN5_TETNG Q4STN5_TETNG -----------PVYCICRLPYDVTQFMIECDACKDWFHGSCVGVDEDDAPDIDIYHCPNC Q6P949_DANRE Q6P949_DANRE -----------PVYCICRLPYDVTQFMIECDACKDWFHGSCVGVDEDEAPDIDIYHCPNC MATCH CONSENSUS ?????????????????????????FMIECD?C?DWFHG?CV???E??A?DID?YHCPNC

A5PL83_DANRE A5PL83_DANRE EPIHGPYMMKKHNNWHRHDYTEPNDGTRPVQAGTAVFVKELQARSFASGD-IL-VQMQGN Q5RHD1_DANRE Q5RHD1_DANRE EPIHGPYMMKKHNNWHRHDYTEPNDGTRPVQAGTAVFVKELQARSFASGD-IL-VQMQGN Q08D35_XENTR Q08D35_XENTR EVLHGPSQLKKRRNWHRHDYTEPDDGTKPVQAGTRTFIQQLQARSFPSADDLL-LKMNGS A4D1S9_HUMAN A4D1S9_HUMAN AVLHGSSLMKKRRNWHRHDYTEIDDGSKPVQAGTRTFIKELRSRVFPSADEII-IKMHGS JHD1D_HUMAN JHD1D_HUMAN AVLHGSSLMKKRRNWHRHDYTEIDDGSKPVQAGTRTFIKELRSRVFPSADEII-IKMHGS A6H6E5_MOUSE A6H6E5_MOUSE AALHGSSLMKKRRNWHRHDYTEVDDGSKPVQAGTRAFVKELRSRVFPSADEII-VKMHGS JHD1D_MOUSE JHD1D_MOUSE AALHGSSLMKKRRNWHRHDYTEVDDGSKPVQAGTRAFVKELRSRVFPSADEII-VKMHGS B9EKK1_MOUSE B9EKK1_MOUSE EAVFGPSIMKNWHGSPRVH---DALKRKPLMTGSPTSIHQIQGRIFESSDKVI-LKPTGS B6D5P9_PERLE B6D5P9_PERLE EVLHGPSIMKKQHGSCQEL---TSLKREPLRNVSLLFIHQLQSKTFESSEEVL-LKPTGS B6D5P7_PERPL B6D5P7_PERPL EVLHGPSIMKKQHGSSQEL---TGLKREPLRNVSLLFIHQLQSKTFESCEEVI-LKPTGS B6D5P8_PERMA B6D5P8_PERMA EVLHGPSIMKKQHGSSQEL---TGLKREPLRNVSLLFIHQLQSKTFESCEEVI-LKPTGS B6D5Q0_PERER B6D5Q0_PERER EVLHGPSIIKKQHGSSQEH---VGLKSEPVKTGSPLFIHQLQGKTFESSEEVI-LKPTGS B6D5Q1_PERCA B6D5Q1_PERCA EVLHGPSIMKNLHGLSQEH---TSLKMEPVKTGSPLFIHQLQGKNFESSEALICLKTTGS Q28G38_XENTR Q28G38_XENTR QITHGPSVMKRRRGNLKQDPHLSKDLGKPVQTGSASFIKELKSRNFPSAEEII-LKPQGA Q7T0U8_XENLA Q7T0U8_XENLA QITHGPSVMKRRRGNLKQDLHLSKDIGKPVQTGSANFIKELKSRNFPSAEEIV-LKPQGA Q5JPS0_HUMAN Q5JPS0_HUMAN EVLHGPSIMKKRRGSSKGH---DTHKGKPVKTGSPTFVRELRSRTFDSSDEVI-LKPTGN Q5JPS3_HUMAN Q5JPS3_HUMAN ------------------------------------------------------------ PHF8_HUMAN PHF8_HUMAN EVLHGPSIMKKRRGSSKGH---DTHKGKPVKTGSPTFVRELRSRTFDSSDEVI-LKPTGN B7Z911_HUMAN B7Z911_HUMAN EVLHGPSIMKKRRGSSKGH---DTHKGKPVKTGSPTFVRELRSRTFDSSDEVI-LKPTGN Q5JPS2_HUMAN Q5JPS2_HUMAN -----------------------------------------------SSDEVI-LKPTGN Q5JPR9_HUMAN Q5JPR9_HUMAN EVLHGPSIMKKRRGSSKGH---DTHKGKPVKTGSPTFVRELRSRTFDSSDEVI-LKPTGN A2ABV1_MOUSE A2ABV1_MOUSE EVLHGPSIMKKRRGSSKGH---DNHKGKPLKTGSSMFIRELRGRTFDSSDEVI-LKPTGS Q3UZ32_MOUSE Q3UZ32_MOUSE EVLHGPSIMKKRRGSSKGH---DNHKGKPLKTGSSMFIRELRGRTFDSSDEVI-LKPTGS A2ABV3_MOUSE A2ABV3_MOUSE EVLHGPSIMKKRRGSSKGH---DNHKGKPLKTGSSMFIRELRGRTFDSSDEVI-LKPTGS A2ABV2_MOUSE A2ABV2_MOUSE EVLHGPSIMKKRRGSSKGH---DNHKGKPLKTGSSMFIRELRGRTFDSSDEVI-LKPTGS A2ABU8_MOUSE A2ABU8_MOUSE EVLHGPSIMKKRRGSSKGH---DNHKGKPLKTGSSMFIRELRGRTFDSSDEVI-LKPTGS PHF8_MOUSE PHF8_MOUSE EVLHGPSIMKKRRGSSKGH---DNHKGKPLKTGSSMFIRELRGRTFDSSDEVI-LKPTGS PHF2_HUMAN PHF2_HUMAN EKTHGKSTLKKKRTWHKHG-PGQAPDVKPVQNGSQLFIKELRSRTFPSAEDVV-ARVPGS PHF2_MOUSE PHF2_MOUSE EKTHGKSTLKKKRTWHKHG-PGPTPDVKPVQNGSQLFIKELRSRTFPSAEDVV-SRVPGS Q6A023_MOUSE Q6A023_MOUSE -----KSTLKKKRTWHKHG-PGPTPDVKPVQNGSQLFIKELRSRTFPSAEDVV-SRVPGS Q4STN5_TETNG Q4STN5_TETNG EKTHGKSTLKKKRNWSKYD-TGQSTDIRAVQNGSQVFIKELRSRTFPSADDVV-VKLSGL Q6P949_DANRE Q6P949_DANRE EKTHGKSTLKKKKSWNKHD-TGQSGDVRPVQNGSQVFIKELRSRTFPSSEDVV-VKLSGS MATCH CONSENSUS ???HG?S??KK?????????????????P???G???F???L????F?S???????K??G?

A5PL83_DANRE A5PL83_DANRE QVTKRFLEKEGFNYPIVVHDLDGLGLKLPPPSFSVSDVEHYVGANKVIDVIDVAKQADSK Q5RHD1_DANRE Q5RHD1_DANRE QVTKRFLEKEGFNYPIVVHDLDGLGLKLPPPSFSVSDVEHYVGANKVIDVIDVAKQADSK Q08D35_XENTR Q08D35_XENTR QLTQRYLEKQGFNLPIMVPRLDDLGLRLPPPTFSVMDVERYVGGEKIIDVIDVARQADSK A4D1S9_HUMAN A4D1S9_HUMAN QLTQRYLEKHGFDVPIMVPKLDDLGLRLPSPTFSVMDVERYVGGDKVIDVIDVARQADSK JHD1D_HUMAN JHD1D_HUMAN QLTQRYLEKHGFDVPIMVPKLDDLGLRLPSPTFSVMDVERYVGGDKVIDVIDVARQADSK A6H6E5_MOUSE A6H6E5_MOUSE QLTQRYLEKHGFDVPIMVPKLDDLGLRLPSPAFSVMDVERYVGGDKVIDVIDVARQADSK JHD1D_MOUSE JHD1D_MOUSE QLTQRYLEKHGFDVPIMVPKLDDLGLRLPSPAFSVMDVERYVGGDKVIDVIDVARQADSK B9EKK1_MOUSE B9EKK1_MOUSE HLTVEFLLESSFSIPILVLKKDGLGMTLPPTSFTVRDVEQYVGSDREVDVIDVACQASSK B6D5P9_PERLE B6D5P9_PERLE QLTVEFLEEHSFSRPILILKKDGLGMKLPPTTFTVRDVEKWVGSDKVIDAIDVASQASFK B6D5P7_PERPL B6D5P7_PERPL QLTVEFXEKHSFSRPILILKKDGLGMKIPPTTFTVRDVEKWVGSDNVIDAIDVASQASFK B6D5P8_PERMA B6D5P8_PERMA QLTVEFLEKHSFSRPILILKKDGLGMKIPPTTFTVRDVEKWVGSDNVIDAIDVASQASFK B6D5Q0_PERER B6D5Q0_PERER QLTVEFLEESSFSRPILVLKKDGLGMKLPPSSFTVRDVEQYVGSDKEIHAIDVACQDSCK B6D5Q1_PERCA B6D5Q1_PERCA QLTVEFLEESSFSRPILVLKKEGLGMKVPPTSFTVRDVEQYVGSDKEIDAIDVACQASCK Q28G38_XENTR Q28G38_XENTR QLTVEYLEENSFSVPILVLKKDGLGMTLPAPTFTVSDVEYYVGPEKEIDVIDVTRQADLK Q7T0U8_XENLA Q7T0U8_XENLA QLTVEYLEENSFSVPILVLKKDGLGMTLPAPTFTVSDVEYYVGPEKEIDVIDVTRQADLK Q5JPS0_HUMAN Q5JPS0_HUMAN QLTVEFLEENSFSVPILVLKKDGLGMTLPSPSFTVRDVEHYVGSDKEIDVIDVTRQADCK Q5JPS3_HUMAN Q5JPS3_HUMAN ------------------------------------------------------------ PHF8_HUMAN PHF8_HUMAN QLTVEFLEENSFSVPILVLKKDGLGMTLPSPSFTVRDVEHYVGSDKEIDVIDVTRQADCK B7Z911_HUMAN B7Z911_HUMAN QLTVEFLEENSFSVPILVLKKDGLGMTLPSPSFTVRDVEHYVGSDKEIDVIDVTRQADCK Q5JPS2_HUMAN Q5JPS2_HUMAN QLTVEFLEENSFSVPILVLKKDGLGMTLPSPSFTVRDVEHYVGSDKEIDVIDVTRQADCK Q5JPR9_HUMAN Q5JPR9_HUMAN QLTVEFLEENSFSVPILVLKKDGLGMTLPSPSFTVRDVEHYVGSDKEIDVIDVTRQADCK A2ABV1_MOUSE A2ABV1_MOUSE QLTVEFLEENSFSVPILVLKKDGLGMTLPSPSFTVRDVEHYVGSDKEIDVIDVARQADCK Q3UZ32_MOUSE Q3UZ32_MOUSE QLTVEFLEENSFSVPILVLKKDGLGMTLPSPSFTVRDVEHYVGSDKEIDVIDVARQADCK A2ABV3_MOUSE A2ABV3_MOUSE QLTVEFLEENSFSVPILVLKKDGLGMTLPSPSFTVRDVEHYVGSDKEIDVIDVARQADCK A2ABV2_MOUSE A2ABV2_MOUSE QLTVEFLEENSFSVPILVLKKDGLGMTLPSPSFTVRDVEHYVGSDKEIDVIDVARQADCK A2ABU8_MOUSE A2ABU8_MOUSE QLTVEFLEENSFSVPILVLKKDGLGMTLPSPSFTVRDVEHYVGSDKEIDVIDVARQADCK PHF8_MOUSE PHF8_MOUSE QLTVEFLEENSFSVPILVLKKDGLGMTLPSPSFTVRDVEHYVGSDKEIDVIDVARQADCK PHF2_HUMAN PHF2_HUMAN QLTLGYMEEHGFTEPILVPKKDGLGLAVPAPTFYVSDVENYVGPERSVDVTDVTKQKDCK PHF2_MOUSE PHF2_MOUSE QLTVGYMEEHGFTEPILVPKKDGLGLAVPAPTFYVSDVENYVGPERSVDVTDVTKQKDCK Q6A023_MOUSE Q6A023_MOUSE QLTVGYMEEHGFTEPILVPKKDGLGLAVPAPTFYVSDVENYVGPERSVDVTDVTKQKDCK Q4STN5_TETNG Q4STN5_TETNG QLTVEYLEQDGFSEPILAQKKEGLGMSMPAPTFYISDVENYVGPDVIVDVVDVTKQTDSK Q6P949_DANRE Q6P949_DANRE QLTLEYLEENGFNEPILIQKKDGLGMAMPAPTFYVSDVENYVGPDVLVDVVDVTKQTDSK MATCH CONSENSUS QLT???LE???F??PI?V?K?DGLG???P???F?V?DVE?YVG?????DVIDV??Q???K

A5PL83_DANRE A5PL83_DANRE MKLGEFVKYYHQPERPKVLNVISLEFSDTRMSNLVVVPDIAQKMSWVENYWPDDSFFPKP Q5RHD1_DANRE Q5RHD1_DANRE MKLGEFVKYYYQPERPKVLNVISLEFSDTRMSNLVVVPDIAQKMSWVENYWPDDSFFPKP Q08D35_XENTR Q08D35_XENTR MKLKNFVKYFMNPDRPKVLNVISLEFSDTKMADLVKVPDISKKLSWVENYWPDDSFFTKP A4D1S9_HUMAN A4D1S9_HUMAN MTLHNYVKYFMNPNRPKVLNVISLEFSDTKMSELVEVPDIAKKLSWVENYWPDDSVFPKP JHD1D_HUMAN JHD1D_HUMAN MTLHNYVKYFMNPNRPKVLNVISLEFSDTKMSELVEVPDIAKKLSWVENYWPDDSVFPKP A6H6E5_MOUSE A6H6E5_MOUSE MTLHNYVKYFMNPDRPKVLNVISLEFSDTKMSELVEVPDIARKLSWVENYWPDDSVFPKP JHD1D_MOUSE JHD1D_MOUSE MTLHNYVKYFMNPDRPKVLNVISLEFSDTKMSELVEVPDIARKLSWVENYWPDDSVFPKP B9EKK1_MOUSE B9EKK1_MOUSE MMLGDFVKYYYSRKREKTFNVINLEFSNTGLSNIVEMPKIVRKLSWVENLWPEDCGFERP B6D5P9_PERLE B6D5P9_PERLE MRLGDFVKYYYSEKRENAFNIISLEFSNTLLSNIVEMPKIVRKLSWVENLWPEXCGFERP B6D5P7_PERPL B6D5P7_PERPL MRLGDFVKYYYSEKRENVFNIISLEFSNTLLSNIVEMPKIVRKLSWVENLWPEECGFERP B6D5P8_PERMA B6D5P8_PERMA MRLGDFVKYYYSEKRENVFNIISLEFSNTLLSNIVEMPKIVRKLSWVENLWPEECGFDRP B6D5Q0_PERER B6D5Q0_PERER MMLGDFVKYYYSGKREKVFNVISLEFSNTRLSTIVERPKIVHRISWVENLWPEECDFERP B6D5Q1_PERCA B6D5Q1_PERCA MMLGDFVKYYYSGNREKVFNVISLEFSDTRLSTIVEMPKIVGKLSWVENLWPEECGFERP Q28G38_XENTR Q28G38_XENTR MKLKDFVKYYNSPKREKVLNVISLEFSETRLTNLVETPKIVRKLSWVENLWPEQSVFERP Q7T0U8_XENLA Q7T0U8_XENLA MKLKDFVKYYNSPKREKVLNLISLEFSETRLSNLVETPKIVRKLSWVENLWPEQSVFERP Q5JPS0_HUMAN Q5JPS0_HUMAN MKLGDFVKYYYSGKREKVLNVISLEFSDTRLSNLVETPKIVRKLSWVENLWPEECVFERP Q5JPS3_HUMAN Q5JPS3_HUMAN ------------------------------------------------------------ PHF8_HUMAN PHF8_HUMAN MKLGDFVKYYYSGKREKVLNVISLEFSDTRLSNLVETPKIVRKLSWVENLWPEECVFERP B7Z911_HUMAN B7Z911_HUMAN MKLGDFVKYYYSGKREKVLNVISLEFSDTRLSNLVETPKIVRKLSWVENLWPEECVFERP Q5JPS2_HUMAN Q5JPS2_HUMAN MKLGDFVKYYYSGKREKVLNVISLEFSDTRLSNLVETPKIVRKLSWVENLWPEECVFERP Q5JPR9_HUMAN Q5JPR9_HUMAN MKLGDFVKYYYSGKREKVLNVISLEFSDTRLSNLVETPKIVRKLSWVENLWPEECVFERP A2ABV1_MOUSE A2ABV1_MOUSE MKLGDFVKYYYSGKREKVLNVISLEFSDTRLSNLVETPRIVRKLSWVENLWPEECVFERP Q3UZ32_MOUSE Q3UZ32_MOUSE MKLGDFVKYYYSGKREKVLNVISLEFSDTRLSNLVETPRIVRKLSWVENLWPEECVFERP A2ABV3_MOUSE A2ABV3_MOUSE MKLGDFVKYYYSGKREKVLNVISLEFSDTRLSNLVETPRIVRKLSWVENLWPEECVFERP A2ABV2_MOUSE A2ABV2_MOUSE MKLGDFVKYYYSGKREKVLNVISLEFSDTRLSNLVETPRIVRKLSWVENLWPEECVFERP A2ABU8_MOUSE A2ABU8_MOUSE MKLGDFVKYYYSGKREKVLNVISLEFSDTRLSNLVETPRIVRKLSWVENLWPEECVFERP PHF8_MOUSE PHF8_MOUSE MKLGDFVKYYYSGKREKVLNVISLEFSDTRLSNLVETPRIVRKLSWVENLWPEECVFERP PHF2_HUMAN PHF2_HUMAN MKLKEFVDYYYSTNRKRVLNVTNLEFSDTRMSSFVEPPDIVKKLSWVENYWPDDALLAKP PHF2_MOUSE PHF2_MOUSE MKLKEFVDYYYSTNRKRVLNVTNLEFSDTRMSSFVEPPDIVKKLSWVENYWPDDALLAKP Q6A023_MOUSE Q6A023_MOUSE MKLKEFVDYYYSTNRKRVLNVTNLEFSDTRMSSFVEPPDIVKKLSWVENYWPDDALLAKP Q4STN5_TETNG Q4STN5_TETNG MKLKEFVDYYYSTNRKKVLNVINLEFSDTRMSSVVESPLIVRQLSWVENYWPDDALLGKP Q6P949_DANRE Q6P949_DANRE MKLKEFVDYYYSTNRKKVLNVINLEFSDARMANIVESPQIVRKLSWVENYWPDDALLGKP MATCH CONSENSUS M?L??FVKYY????R??V?NVI?LEFS?T??S??VE?P?I??KLSWVEN?WP????F??P

A5PL83_DANRE A5PL83_DANRE FVQKYCLMGMKNSYTDFHIDFGGTSVWYHVLWGEKIFYLIKPTKANLALYEAWSSSPNQS Q5RHD1_DANRE Q5RHD1_DANRE FVQKYCLMGMKNSYTDFHIDFGGTSVWYHVLWGEKIFYLIKPTKANLALYEAWSSSPNQS Q08D35_XENTR Q08D35_XENTR FVQKYCLMGVQDSYTDFHIDFGGTSVWYHVLWGEKVFYLIKPSDENLALYESWSSSVTQS A4D1S9_HUMAN A4D1S9_HUMAN FVQKYCLMGVQDSYTDFHIDFGGTSVWYHVLWGEKIFYLIKPTDENLARYESWSSSVTQS JHD1D_HUMAN JHD1D_HUMAN FVQKYCLMGVQDSYTDFHIDFGGTSVWYHVLWGEKIFYLIKPTDENLARYESWSSSVTQS A6H6E5_MOUSE A6H6E5_MOUSE FVQKYCLMGVQDSYTDFHIDFGGTSVWYHVLWGEKIFYLIKPTNENLALYESWSSSVTQS JHD1D_MOUSE JHD1D_MOUSE FVQKYCLMGVQDSYTDFHIDFGGTSVWYHVLWGEKIFYLIKPTNENLALYESWSSSVTQS B9EKK1_MOUSE B9EKK1_MOUSE NVQKYCLMSMQNSYTDFHIEFGGTSAWYHVVKGEKIFYLIRPTDANLTLFECWSNSSNQK B6D5P9_PERLE B6D5P9_PERLE NVQKYCFMSVKDSYTDFHIAFGAPSIWYHVLKGEKIFYLIHPTDDNLTLFECWNKSYKHK B6D5P7_PERPL B6D5P7_PERPL NVQKYCFMSVKDSYTDFHIAFGAPSIWYHVLKGEKIFYLIHPTNDNLTLFECWNKFSKHK B6D5P8_PERMA B6D5P8_PERMA NVQKYCFMSVKDSYTDFHIAFGAPSIWYHVLKGEKIFYLIQPTNDNLTLFECWNKFSKHK B6D5Q0_PERER B6D5Q0_PERER NVQKCCFMSVQGSYTDFHIEFGALSIWSHVLKGEKIFYLIHPTNANLTLFECWSNSSKQK B6D5Q1_PERCA B6D5Q1_PERCA NVQKTCFMSVQDSYTDFHIEFGAHSIWSHVLKGEKIFYLIHPTNANLSLFECWSNSSKQK Q28G38_XENTR Q28G38_XENTR NVQKYCLMGVKDSYTDFHIDFGGTSVWYHVLKGEKIFYLIQPTKTNLALFECWSSSSNQN Q7T0U8_XENLA Q7T0U8_XENLA NVQKYCLMGVKDSYTDFHIDFGGTSVWYHVLKGEKIFYLIQPTKTNLALFECWSSSSNQN Q5JPS0_HUMAN Q5JPS0_HUMAN NVQKYCLMSVRDSYTDFHIDFGGTSVWYHVLKGEKIFYLIRPTNANLTLFECWSSSSNQN Q5JPS3_HUMAN Q5JPS3_HUMAN --------SVRDSYTDFHIDFGGTSVWYHVLKGEKIFYLIRPTNANLTLFECWSSSSNQN PHF8_HUMAN PHF8_HUMAN NVQKYCLMSVRDSYTDFHIDFGGTSVWYHVLKGEKIFYLIRPTNANLTLFECWSSSSNQN B7Z911_HUMAN B7Z911_HUMAN NVQKYCLMSVRDSYTDFHIDFGGTSVWYHVLKGEKIFYLIRPTNANLTLFECWSSSSNQN Q5JPS2_HUMAN Q5JPS2_HUMAN NVQKYCLMSVRDSYTDFHIDFGGTSVWYHVLKGEKIFYLIRPTNANLTLFECWSSSSNQN Q5JPR9_HUMAN Q5JPR9_HUMAN NVQKYCLMSVRDSYTDFHIDFGGTSVWYHVLKGEKIFYLIRPTNANLTLFECWSSSSNQN A2ABV1_MOUSE A2ABV1_MOUSE NVQKYCLMSVRDSYTDFHIDFGGTSVWYHVLKGEKIFYLIRPTNANLTLFECWSSSSNQN Q3UZ32_MOUSE Q3UZ32_MOUSE NVQKYCLMSVRDSYTDFHIDFGGTSVWYHVLKGEKIFYLIRPTNANLTLFECWSSSSNQN A2ABV3_MOUSE A2ABV3_MOUSE NVQKYCLMSVRDSYTDFHIDFGGTSVWYHVLKGEKIFYLIRPTNANLTLFECWSSSSNQN A2ABV2_MOUSE A2ABV2_MOUSE NVQKYCLMSVRDSYTDFHIDFGGTSVWYHVLKGEKIFYLIRPTNANLTLFECWSSSSNQN A2ABU8_MOUSE A2ABU8_MOUSE NVQKYCLMSVRDSYTDFHIDFGGTSVWYHVLKGEKIFYLIRPTNANLTLFECWSSSSNQN PHF8_MOUSE PHF8_MOUSE NVQKYCLMSVRDSYTDFHIDFGGTSVWYHVLKGEKIFYLIRPTNANLTLFECWSSSSNQN PHF2_HUMAN PHF2_HUMAN KVTKYCLICVKDSYTDFHIDSGGASAWYHVLKGEKTFYLIRPASANISLYERWRSASNHS PHF2_MOUSE PHF2_MOUSE KVTKYCLICVKDSYTDFHIDSGGASAWYHVLKGEKIFYLIRPASANISLYERWRSASNHS Q6A023_MOUSE Q6A023_MOUSE KVTKYCLICVKDSYTDFHIDSGGASAWYHVLKGEKIFYLIRPASANISLYERWRSASNHS Q4STN5_TETNG Q4STN5_TETNG KVTKYCLICVKDSYTDFHIECGGASVWYHVLKGEQIFFLIKPTSANLSLYERWRSSSNHS Q6P949_DANRE Q6P949_DANRE KVSKYCLICVKDSYTDFHIECGGASVWYHVLKGEKIFFLIKPTSANLSLYERWRSSSNHS MATCH ::.******* *. * * **: **: *:**:*:. *:: :* * . .:. CONSENSUS ?VQKYCLM?V?DSYTDFHI?FGG?S?WYHVL?GEKIFYLI?PT??NL?L?E?W?SS????

A5PL83_DANRE A5PL83_DANRE EVFFGEKVDKCYKCVVKQGTTILLPT------------------------GWIHAVLTSQ Q5RHD1_DANRE Q5RHD1_DANRE EVFFGEKVDKCYKCVVKQGTTILLPT------------------------GWIHAVLTSQ Q08D35_XENTR Q08D35_XENTR EEFFGDKVDKCYKCVVKQGHTLFVPT------------------------GWIHAVLTSQ A4D1S9_HUMAN A4D1S9_HUMAN EVFFGDKVDKCYKCVVKQGHTLFVPT------------------------GWIHAVLTSQ JHD1D_HUMAN JHD1D_HUMAN EVFFGDKVDKCYKCVVKQGHTLFVPT------------------------GWIHAVLTSQ A6H6E5_MOUSE A6H6E5_MOUSE EVFFGDKVDKCYKCVVKQGHTLFVPT------------------------GWIHAVLTSQ JHD1D_MOUSE JHD1D_MOUSE EVFFGDKVDKCYKCVVKQGHTLFVPT------------------------GWIHAVLTSQ B9EKK1_MOUSE B9EKK1_MOUSE EIFFGDQVDRCYKCSVKQGQTLFIPT------------------------GWIYAVLTPV B6D5P9_PERLE B6D5P9_PERLE EVFFGDQVDKCYKCSVKQGQTLFIPA------------------------GWIHAVLTPV B6D5P7_PERPL B6D5P7_PERPL EVFFGDQVDKCYKCSVKQGQTLFIPA------------------------GWIHAVLTPV B6D5P8_PERMA B6D5P8_PERMA EVFFGDQVDKCYKCSVKQGQTLFIPA------------------------GWIHAVLTPV B6D5Q0_PERER B6D5Q0_PERER EMFFGDQVDKCYKCSVKQGQTIFIPA------------------------GWIHAVLTPV B6D5Q1_PERCA B6D5Q1_PERCA EMFFGDQVDKCYKCCVKQGQTLFIPA------------------------GWIHAVLTPV Q28G38_XENTR Q28G38_XENTR EMFFGDQVDKCYRCPVKQGQTLFIPT------------------------GWIHSVLTPV Q7T0U8_XENLA Q7T0U8_XENLA EMFFGDQVDKCYRCPVKQGQTLFIPT------------------------GWIHAVLTPV Q5JPS0_HUMAN Q5JPS0_HUMAN EMFFGDQVDKCYKCSVKQGQTLFIPT------------------------GWIHAVLTPV Q5JPS3_HUMAN Q5JPS3_HUMAN EMFFGDQVDKCYKCSVKQGQTLFIPT------------------------GWIHAVLTPV PHF8_HUMAN PHF8_HUMAN EMFFGDQVDKCYKCSVKQGQTLFIPT------------------------GWIHAVLTPV B7Z911_HUMAN B7Z911_HUMAN EMFFGDQVDKCYKCSVKQGQTLFIPT------------------------GWIHAVLTPV Q5JPS2_HUMAN Q5JPS2_HUMAN EMFFGDQVDKCYKCSVKQGQTLFIPT------------------------GWIHAVLTPV Q5JPR9_HUMAN Q5JPR9_HUMAN EMFFGDQVDKCYKCSVKQGQTLFIPT------------------------GWIHAVLTPV A2ABV1_MOUSE A2ABV1_MOUSE EMFFGDQVEKCYKCSVKQGQTLFIPT------------------------GWIHAVLTPV Q3UZ32_MOUSE Q3UZ32_MOUSE EMFFGDQVEKCYKCSVKQGQTLFIPT------------------------GWIHAVLTPM A2ABV3_MOUSE A2ABV3_MOUSE EMFFGDQVEKCYKCSVKQGQTLFIPT------------------------GWIHAVLTPV A2ABV2_MOUSE A2ABV2_MOUSE EMFFGDQVEKCYKCSVKQGQTLFIPT------------------------GWIHAVLTPV A2ABU8_MOUSE A2ABU8_MOUSE EMFFGDQVEKCYKCSVKQGQTLFIPT------------------------GWIHAVLTPV PHF8_MOUSE PHF8_MOUSE EMFFGDQVEKCYKCSVKQGQTLFIPT------------------------GWIHAVLTPV PHF2_HUMAN PHF2_HUMAN EMFFADQVDKCYKCIVKQGQTLFIPS------------------------GWIYATLTPV PHF2_MOUSE PHF2_MOUSE EMFFADQVDRCYKCTVKQGQTLFIPS------------------------GWIYATLTPV Q6A023_MOUSE Q6A023_MOUSE EMFFADQVDRCYKCTVKQGQTLFIPS------------------------GWIYATLTPV Q4STN5_TETNG Q4STN5_TETNG EMFFADQVDKCYKCTLKQGQTLFIPSACRPMITTKSTNLFTKFTKMLTAGGWINAMLTPV Q6P949_DANRE Q6P949_DANRE EMFFADQVDKCYKCTLKQGQTLFIPS------------------------GWINAILTPV MATCH * **.::*::**:* :*** *:::*: *** : **. CONSENSUS E?FFGD?VDKCYKC?VKQG?TLF?P?????????????????????????GWIHAVLT??

A5PL83_DANRE A5PL83_DANRE DSMAFGGNFLHNLNIDMQL--------------------------RCYEMERRLKTPDLF Q5RHD1_DANRE Q5RHD1_DANRE DSMAFGGNFLHNLNIDMQL--------------------------RCYEMERRLKTPDLF Q08D35_XENTR Q08D35_XENTR DCMAFGGNFLHNLNIGMQL--------------------------RCYEMEKRLKTPDLF A4D1S9_HUMAN A4D1S9_HUMAN DCMAFGGNFLHNLNIGMQL--------------------------RCYEMEKRLKTPDLF JHD1D_HUMAN JHD1D_HUMAN DCMAFGGNFLHNLNIGMQL--------------------------RCYEMEKRLKTPDLF A6H6E5_MOUSE A6H6E5_MOUSE DCMAFGGNFLHNLNIGMQL--------------------------RCYEMEKRLKTPDLF JHD1D_MOUSE JHD1D_MOUSE DCMAFGGNFLHNLNIGMQL--------------------------RCYEMEKRLKTPDLF B9EKK1_MOUSE B9EKK1_MOUSE DCLAFGGNFLHSLNIEMQL--------------------------KVYEIEKHLCTTDLF B6D5P9_PERLE B6D5P9_PERLE DCLAFGGKFIHSLNIEMQL--------------------------KAYEIQKKLSIADVF B6D5P7_PERPL B6D5P7_PERPL DCLAFGGKFIHSLNIEMQL--------------------------KAYEIQKKLSIADLF B6D5P8_PERMA B6D5P8_PERMA DCLAFGGKFIHSLNIEMQL--------------------------KAYEIQKKLSIADLF B6D5Q0_PERER B6D5Q0_PERER DCLAFGGKFLHSLNIEMQL--------------------------KAYEIQKKLSVAGLF B6D5Q1_PERCA B6D5Q1_PERCA DCLAFGGKFLHSLNIEMQL--------------------------KAYEIQKKLSLADLF Q28G38_XENTR Q28G38_XENTR DCLAFGGNFLHSLNIAIQL--------------------------RAYEIEKRLSTADLF Q7T0U8_XENLA Q7T0U8_XENLA DCLAFGGNFLHSLSIAMQL--------------------------RAYEIEKRLSTADLF Q5JPS0_HUMAN Q5JPS0_HUMAN DCLAFGGNFLHSLNIEMQL--------------------------KAYEIEKRLSTADLF Q5JPS3_HUMAN Q5JPS3_HUMAN DCLAFGGNFLHSLNIEMQL--------------------------KAYEIEKRLSTADLF PHF8_HUMAN PHF8_HUMAN DCLAFGGNFLHSLNIEMQL--------------------------KAYEIEKRLSTADLF B7Z911_HUMAN B7Z911_HUMAN DCLAFGGNFLHSLNIEMQL--------------------------KAYEIEKRLSTADLF Q5JPS2_HUMAN Q5JPS2_HUMAN DCLAFGGNFLHSLNIEMQL--------------------------KAYEIEKRLSTADLF Q5JPR9_HUMAN Q5JPR9_HUMAN DCLAFGGNFLHSLNIEMQL--------------------------KAYEIEKRLSTADLF A2ABV1_MOUSE A2ABV1_MOUSE DCLAFGGNFLHSLNIEMQL--------------------------KAYEIEKRLSTADLF Q3UZ32_MOUSE Q3UZ32_MOUSE DCLAFGGNFLHSLNIEMQL--------------------------KAYEIEKRLSTADLF A2ABV3_MOUSE A2ABV3_MOUSE DCLAFGGNFLHSLNIEMQL--------------------------KAYEIEKRLSTADLF A2ABV2_MOUSE A2ABV2_MOUSE DCLAFGGNFLHSLNIEMQL--------------------------KAYEIEKRLSTADLF A2ABU8_MOUSE A2ABU8_MOUSE DCLAFGGNFLHSLNIEMQL--------------------------KAYEIEKRLSTADLF PHF8_MOUSE PHF8_MOUSE DCLAFGGNFLHSLNIEMQL--------------------------KAYEIEKRLSTADLF PHF2_HUMAN PHF2_HUMAN DCLAFAGHFLHSLSVEMQM--------------------------RAYEVERRLKLGSLT PHF2_MOUSE PHF2_MOUSE DCLAFAGHFLHSLSVEMQM--------------------------RAYEVERRLKLGSLT Q6A023_MOUSE Q6A023_MOUSE DCLAFAGHFLHSLSVEMQM--------------------------RAYEVERRLKLGSLT Q4STN5_TETNG Q4STN5_TETNG DCLAFSGHFIHNLSVEMQMRFGSWPGWTLPQAGFCLVGTDLFILHRAYEIEKRLKIRTLT Q6P949_DANRE Q6P949_DANRE DCLAFSGHFVHSLSVEMQM--------------------------RAYEVEKRLKVASLT MATCH *.:**.*:*:*.*.: :*: : **::::* : CONSENSUS DC?AFGG?FLH?LNI?MQL????????????????????????????YE?EKRL???DLF

A5PL83_DANRE A5PL83_DANRE KFPYFEAICWYVAKNLLETLKELRENKCEAQGFLVNGVKALISSLKMWLRRE-LTQPNSE Q5RHD1_DANRE Q5RHD1_DANRE KFPYFEAICWYVAKNLLETLKELRENKCEAQGFLVNGVKALISSLKMWLRRE-LTQPNSE Q08D35_XENTR Q08D35_XENTR KFPFFEAICWFVAKNLLETLKELKEDGFHPPNYLKHGVKALISALKSWMKKESVAEHAFE A4D1S9_HUMAN A4D1S9_HUMAN KFPFFEAICWFVAKNLLETLKELREDGFQPQTYLVQGVKALHTALKLWMKKELVSEHAFE JHD1D_HUMAN JHD1D_HUMAN KFPFFEAICWFVAKNLLETLKELREDGFQPQTYLVQGVKALHTALKLWMKKELVSEHAFE A6H6E5_MOUSE A6H6E5_MOUSE KFPFFEAICWFVAKSLLETLKELKEDGFQPQSYLVQGVKALHTALKLWMKKELVSEHAFE JHD1D_MOUSE JHD1D_MOUSE KFPFFEAICWFVAKSLLETLKELKEDGFQPQSYLVQGVKALHTALKLWMKKELVSEHAFE B9EKK1_MOUSE B9EKK1_MOUSE KFPSFETICWHVGKHILDIFKGLRENGRCPASFLVHGGKALNLAFQAWTRKEVLPDHDNE B6D5P9_PERLE B6D5P9_PERLE ILPRFETICWHVGKEILDILRGLREQRRCPASYLVWGCKALAKAXQAWTRKEVLPDHEDE B6D5P7_PERPL B6D5P7_PERPL IFPRFETICWHVGKEILDILGGLXEHGRCPASYLVRGCKALAKAFQAWTRKEVLPDHEDE B6D5P8_PERMA B6D5P8_PERMA IFPRFETICWHVGKEILDILGGLREHGRCPAYYLVQGCKALGKAFQAWTRKEVLPDHEDE B6D5Q0_PERER B6D5Q0_PERER MFPSFETICWHVGKQILNILGGLREQGTCPASYLVRGCKALRMAFEAWTRKEDLPDHEDK B6D5Q1_PERCA B6D5Q1_PERCA MFPSFETICWHVGEQILDILRGLREQGRCPASYLVRGCKALGMAFQAWTKKNVLPDHEDK Q28G38_XENTR Q28G38_XENTR KFPNFETICWYVGKHLLDTFRGLRENRRQPASYLLHGAKALNTAFRGWTKKEALMDHEEE Q7T0U8_XENLA Q7T0U8_XENLA KFPNFETICWYVGKHLLDTFRGLRENRRQPASYLLHGAKALNTTFRAWTKKEALMDHEEE Q5JPS0_HUMAN Q5JPS0_HUMAN RFPNFETICWYVGKHILDIFRGLRENRRHPASYLVHGGKALNLAFRAWTRKEALPDHEDE Q5JPS3_HUMAN Q5JPS3_HUMAN RFPNFETICWYVGKHILDIFRGLRENRRHPASYLVHGGKALNLAFRAWTRKEALPDHEDE PHF8_HUMAN PHF8_HUMAN RFPNFETICWYVGKHILDIFRGLRENRRHPASYLVHGGKALNLAFRAWTRKEALPDHEDE B7Z911_HUMAN B7Z911_HUMAN RFPNFETICWYVGKHILDIFRGLRENRRHPASYLVHGGKALNLAFRAWTRKEALPDHEDE Q5JPS2_HUMAN Q5JPS2_HUMAN RFPNFETICWYVGKHILDIFRGLRENRRHPASYLVHGGKALNLAFRAWTRKEALPDHEDE Q5JPR9_HUMAN Q5JPR9_HUMAN RFPNFETICWYVGKHILDIFRGLRENRRHPASYLVHGGKALNLAFRAWTRKEALPDHEDE A2ABV1_MOUSE A2ABV1_MOUSE KFPNFETICWYVGKHILDIFRGLRENRRHPASYLVHGGKALNLAFRAWTKKEALPDHEDE Q3UZ32_MOUSE Q3UZ32_MOUSE KFPNFETICWYVGKHILDIFRGLRENRRHPASYLVHGGKALNLAFRAWTKKEALPDHEDE A2ABV3_MOUSE A2ABV3_MOUSE KFPNFETICWYVGKHILDIFRGLRENRRHPASYLVHGGKALNLAFRAWTKKEALPDHEDE A2ABV2_MOUSE A2ABV2_MOUSE KFPNFETICWYVGKHILDIFRGLRENRRHPASYLVHGGKALNLAFRAWTKKEALPDHEDE A2ABU8_MOUSE A2ABU8_MOUSE KFPNFETICWYVGKHILDIFRGLRENRRHPASYLVHGGKALNLAFRAWTKKEALPDHEDE PHF8_MOUSE PHF8_MOUSE KFPNFETICWYVGKHILDIFRGLRENRRHPASYLVHGGKALNLAFRAWTKKEALPDHEDE PHF2_HUMAN PHF2_HUMAN QFPNFETACWYMGKHLLEAFKGSHKSGKQLPPHLVQGAKILNGAFRSWTKKQALAEHEDE PHF2_MOUSE PHF2_MOUSE QFPNFETACWYMGKHLLEAFKGSHKSGKQLPPHLVQGAKILNGAFRSWTKKQALAEHEDE Q6A023_MOUSE Q6A023_MOUSE QFPNFETACWYMGKHLLEAFKGSHKSGKQLPPHLVQGAKILNGAFRSWTKKQALAEHEDE Q4STN5_TETNG Q4STN5_TETNG PFPNFETACWYVGRHLLERFKALHKVNKQPAPYLLNGAKIINGAFRAWTKKQALLEHEDE Q6P949_DANRE Q6P949_DANRE PFSNFETACWYVGKYYLEQFKGLHKANKQPPPYLVHGAKIVNGAFRSWTKKQALLEHEDE MATCH :. **: **.:.. *: : : .* * * : : . * ::: : : : CONSENSUS ?FP?FE?ICW?V?K??L?????L?E????P??YLV?G?KAL??A???W??KE?L??H??E

A5PL83_DANRE A5PL83_DANRE VPDNIRPGHLIKALSKEIRHLE------DDSNKAVKTQGRAECSLSRST----------- Q5RHD1_DANRE Q5RHD1_DANRE VPDNIRPGHLIKALSKEIRHLE------DDSNKAVKTQGSAECSLSRST----------- Q08D35_XENTR Q08D35_XENTR IPDNIRPGHLIKELSKVIRSVE------E--EGNRPVKSQ--GIHGHCP----------- A4D1S9_HUMAN A4D1S9_HUMAN IPDNVRPGHLIKELSKVIRAIE------E--ENGKPVKSQ--GIPIVCP----------- JHD1D_HUMAN JHD1D_HUMAN IPDNVRPGHLIKELSKVIRAIE------E--ENGKPVKSQ--GIPIVCP----------- A6H6E5_MOUSE A6H6E5_MOUSE IPDNVRPGHLIKELSKVIRAIE------E--ENGKPVKSQ--GIPSVCP----------- JHD1D_MOUSE JHD1D_MOUSE IPDNVRPGHLIKELSKVIRAIE------E--ENGKPVKSQ--GIPSVCP----------- B9EKK1_MOUSE B9EKK1_MOUSE IPKTVQTIQLIEDLAWEIHLVE------DNFQQNIPKTSSTFKFQQLHT----------- B6D5P9_PERLE B6D5P9_PERLE IPKTVQTTQLIEDLAREISLVE------DTFQHNIHKMNTNFEVQQPFL----------- B6D5P7_PERPL B6D5P7_PERPL IPKTVQTTQLIEDLTREISLVE------DTFQHNILKTNTIFEVQQPFL----------- B6D5P8_PERMA B6D5P8_PERMA LPKTMQTTQLIEDLTREISLVE------DTFQHNILKMNTIFEVQQPFL----------- B6D5Q0_PERER B6D5Q0_PERER IPKTVHTTQLIEDLAREISLVE------DTFQHNIQKMNTIFDVQPYFH----------- B6D5Q1_PERCA B6D5Q1_PERCA IPKTVHTTQXIEDLAREISLVE------DTFQHNIQKMNTIFEVQQHIP----------- Q28G38_XENTR Q28G38_XENTR IPETIITSQLIKDLDREIRLME------DIFHQNIEKTGNLMGLTRSPL----------- Q7T0U8_XENLA Q7T0U8_XENLA IPETIITSQLIKDLDREIRLME------DIFHQNIEKTGNLMGLTRSPG----------- Q5JPS0_HUMAN Q5JPS0_HUMAN IPETVRTVQLIKDLAREIRLVE------DIFQQNVGKTSNIFGLQRIFP----------- Q5JPS3_HUMAN Q5JPS3_HUMAN IPETVRTVQLIKDLAREIRLVE------DIFQQNVGKTSNIFGLQRIFP----------- PHF8_HUMAN PHF8_HUMAN IPETVRTVQLIKDLAREIRLVE------DIFQQNVGKTSNIFGLQRIFP----------- B7Z911_HUMAN B7Z911_HUMAN IPETVRTVQLIKDLAREIRLVE-------------------------------------- Q5JPS2_HUMAN Q5JPS2_HUMAN IPETVRTVQLIKDLAREIRLVE------DIFQQNVGKTSNIFGLQRIFP----------- Q5JPR9_HUMAN Q5JPR9_HUMAN IPETVRTVQLIKDLAREIRLVE------DIFQQNVGKTSNIFGLQRIFP----------- A2ABV1_MOUSE A2ABV1_MOUSE IPETVRTVQLIKDLAREIRLVE------DIFQQNVGKTSNIFGLQRIFP----------- Q3UZ32_MOUSE Q3UZ32_MOUSE IPETVRTVQLIKDLAREIRLVE------DIFQQNVGKTSNIFGLQRIFP----------- A2ABV3_MOUSE A2ABV3_MOUSE IPETVRTVQLIKDLAREIRLVE-------------------------------------- A2ABV2_MOUSE A2ABV2_MOUSE IPETVRTVQLIKDLAREIRLVE------DIFQQNVGKTSNIFGLQRIFP----------- A2ABU8_MOUSE A2ABU8_MOUSE IPETVRTVQLIKDLAREIRLVE------DIFQQNVGKTSNIFGLQRIFP----------- PHF8_MOUSE PHF8_MOUSE IPETVRTVQLIKDLAREIRLVE------DIFQQNVGKTSNIFGLQRIFP----------- PHF2_HUMAN PHF2_HUMAN LPEHFKPSQLIKDLAKEIRLSE------NASKAVRPEVNTVASSDEVCDGDREKEEPPSP PHF2_MOUSE PHF2_MOUSE LPEHFRPSQLIKDLAKEIRLSE------NASKTVRPEVNAAASSDEVCDGDREKEEPPSP Q6A023_MOUSE Q6A023_MOUSE LPEHFRPSQLIKDLAKEIRLSE------NASKTVRPEVNAAASSDEVCDGDREKEEPPSP Q4STN5_TETNG Q4STN5_TETNG LPENMKPSQLIKDLAKEIRLSEVVKNLLSMSAKEIPKQNNMEKFE--------------- Q6P949_DANRE Q6P949_DANRE LPENMKPAQLIKDLAKEIRIAEVKQVVSDSQNATKAIKSEPSNSKPPAE----------E MATCH :*. . . : *: * * * CONSENSUS ?P???????LIK?L??EIR??E??????????????????????????????????????

A5PL83_DANRE A5PL83_DANRE --------------------------------LEKGDQAKQAARRLQDHHHHRRRHHHHH Q5RHD1_DANRE Q5RHD1_DANRE --------------------------------LEKGDQAQQAARRLQDHHHHRRRHHHHH Q08D35_XENTR Q08D35_XENTR ---------------------------------------VSRSSHEKSSHHSGRKARRLR A4D1S9_HUMAN A4D1S9_HUMAN --------------------------------------VSRSSNEATSPYHSRRKMRKLR JHD1D_HUMAN JHD1D_HUMAN --------------------------------------VSRSSNEATSPYHSRRKMRKLR A6H6E5_MOUSE A6H6E5_MOUSE --------------------------------------VSRPSNEASPPYHSRRKMRKLR JHD1D_MOUSE JHD1D_MOUSE --------------------------------------VSRPSNEASPPYHSRRKMRKLR B9EKK1_MOUSE B9EKK1_MOUSE -----------------------NSSS--LTRQAHPTSVSKSKLSLPSKNGSEKKSPKYK B6D5P9_PERLE B6D5P9_PERLE ------------------------------------------------------------ B6D5P7_PERPL B6D5P7_PERPL ------------------------------------------------------------ B6D5P8_PERMA B6D5P8_PERMA ------------------------------------------------------------ B6D5Q0_PERER B6D5Q0_PERER ------------------------------------------------------------ B6D5Q1_PERCA B6D5Q1_PERCA ------------------------------------------------------------ Q28G38_XENTR Q28G38_XENTR ------------------------------------TGTPSSSKAALPVKGTNKKGVRAN Q7T0U8_XENLA Q7T0U8_XENLA -------------------------------------APSTSKAAVPFKGSNKKGGRANQ Q5JPS0_HUMAN Q5JPS0_HUMAN ----------------------AGSIP--LTRPAHSTSVSMSRLSLPSKNGSKKKGLKPK Q5JPS3_HUMAN Q5JPS3_HUMAN ----------------------AGSIP--LTRPAHSTSVSMSRLSLPSKNGSKKKGLKPK PHF8_HUMAN PHF8_HUMAN ----------------------AGSIP--LTRPAHSTSVSMSRLSLPSKNGSKKKGLKPK B7Z911_HUMAN B7Z911_HUMAN ------------------------------------------------------------ Q5JPS2_HUMAN Q5JPS2_HUMAN ----------------------AGSIP--LTRPAHSTSVSMSRLSLPSKNGSKKKGLKPK Q5JPR9_HUMAN Q5JPR9_HUMAN ----------------------AGSIP--LTRPAHSTSVSMSRLSLPSKNGSKKKGLKPK A2ABV1_MOUSE A2ABV1_MOUSE ----------------------AGSIP--LTKPAHSTSVSMSKLSLPSKNGSKKKGLKPK Q3UZ32_MOUSE Q3UZ32_MOUSE ----------------------AGSIP--LTKPAHSTSVSMSKLSLPSKNGSKKKGLKPK A2ABV3_MOUSE A2ABV3_MOUSE ------------------------------------------------------------ A2ABV2_MOUSE A2ABV2_MOUSE ----------------------AGSIP--LTKPAHSTSVSMSKLSLPSKNGSKKKGLKPK A2ABU8_MOUSE A2ABU8_MOUSE ----------------------AGSIP--LTKPAHSTSVSMSKLSLPSKNGSKKKGLKPK PHF8_MOUSE PHF8_MOUSE ----------------------AGSIP--LTKPAHSTSVSMSKLSLPSKNGSKKKGLKPK PHF2_HUMAN PHF2_HUMAN IEATPPQSLLEKVSKKKTPKTVKMPKPSKIPKPPKPPKPPRPPKTLKLKDGGKKKGKKSR PHF2_MOUSE PHF2_MOUSE VETTPPRSLLEKVSKKKTSKTVKMPKPSKIPKPPKS---PKPPKTLKLKDGSKKKGKKCK Q6A023_MOUSE Q6A023_MOUSE VETTPPRSLLEKVSKKKTSKTVKMPKPSKIPKPPKS---PKPPKTLKLKDGSKKKGKKCK Q4STN5_TETNG Q4STN5_TETNG ------------------------------------------------------------ Q6P949_DANRE Q6P949_DANRE PPSALSEPEEPMSPAHVSSPSGDKPARKKVPKPPKMPKAPKPPKEPKIKEGGKKKAKKVK MATCH CONSENSUS ????????????????????????????????????????????????????????????

A5PL83_DANRE A5PL83_DANRE HHHHHHHHHH------------------HSRKLPSNLDVLELHTLEVLKRLEVGQLKEDS Q5RHD1_DANRE Q5RHD1_DANRE HHHHHHHHHH------------------HSRKLPSNLDVLELHTLEVLKRLEVGQLKEDS Q08D35_XENTR Q08D35_XENTR D---------------------------HSTKTPTNLDILEHHTREVLKRLEMSPWEED- A4D1S9_HUMAN A4D1S9_HUMAN D---------------------------HNVRTPSNLDILELHTREVLKRLEMCPWEED- JHD1D_HUMAN JHD1D_HUMAN D---------------------------HNVRTPSNLDILELHTREVLKRLEMCPWEED- A6H6E5_MOUSE A6H6E5_MOUSE D---------------------------HNVRTPSNLDILELHTREVLKRLEMCPWEED- JHD1D_MOUSE JHD1D_MOUSE D---------------------------HNVRTPSNLDILELHTREVLKRLEMCPWEED- B9EKK1_MOUSE B9EKK1_MOUSE DTFKKEE---------------------QMSKESSALGPNYQHSCNFMDLNNDQQWKVGC B6D5P9_PERLE B6D5P9_PERLE ------------------------------------------------------------ B6D5P7_PERPL B6D5P7_PERPL ------------------------------------------------------------ B6D5P8_PERMA B6D5P8_PERMA ------------------------------------------------------------ B6D5Q0_PERER B6D5Q0_PERER ------------------------------------------------------------ B6D5Q1_PERCA B6D5Q1_PERCA ------------------------------------------------------------ Q28G38_XENTR Q28G38_XENTR QLIKKVG---------------------RKGRETDA------------DMSPEQPGTPTG Q7T0U8_XENLA Q7T0U8_XENLA MIKKKKK----------------------------------------------------- Q5JPS0_HUMAN Q5JPS0_HUMAN ELFKKAE---------------------RKGKESSALGPAGQLSYNLMDTYSHQALKTGS Q5JPS3_HUMAN Q5JPS3_HUMAN ELFKKAE---------------------RKGKESSALGPAGQLSYNLMDTYSHQALKTGS PHF8_HUMAN PHF8_HUMAN ELFKKAE---------------------RKGKESSALGPAGQLSYNLMDTYSHQALKTGS B7Z911_HUMAN B7Z911_HUMAN ------------------------------------------------------------ Q5JPS2_HUMAN Q5JPS2_HUMAN ELFKKAE---------------------RKGKESSALGPAGQLSYNLMDTYSHQALKTGS Q5JPR9_HUMAN Q5JPR9_HUMAN ELFKKAE---------------------RKGKESSALGPAGQLSYNLMDTYSHQALKTGS A2ABV1_MOUSE A2ABV1_MOUSE DIFKKAE---------------------RKGKQSSALGPAGQLSYNLMDPYSHQALKTGP Q3UZ32_MOUSE Q3UZ32_MOUSE DIFKKAE---------------------RKGKQSSALGPAGQLSYNLMDPYSHQALKTGP A2ABV3_MOUSE A2ABV3_MOUSE ------------------------------------------------------------ A2ABV2_MOUSE A2ABV2_MOUSE DIFKKAE---------------------RKGKQSSALGPAGQLSYNLMDPYSHQALKTGP A2ABU8_MOUSE A2ABU8_MOUSE DIFKKAE---------------------RKGKQSSALGPAGQLSYNLMDPYSHQALKTGP PHF8_MOUSE PHF8_MOUSE DIFKKAE---------------------RKGKQSSALGPAGQLSYNLMDPYSHQALKTGP PHF2_HUMAN PHF2_HUMAN ESASPTIPNLDLLEAHTKEALTKMEPPKKGKATKSVLSVPNKDVVHMQNDVERLEIREQT PHF2_MOUSE PHF2_MOUSE ESASPTIPNLDLLEAHTKEALTKMEPPKKGKTPKSVLSVPNKDTVHTQNDMERLEIREQT Q6A023_MOUSE Q6A023_MOUSE ESASPTIPNLDLLEAHTKEALTKMEPPKKGKTPKSVLSVPNKDTVHTQNDMERLEIREQT Q4STN5_TETNG Q4STN5_TETNG -------------------------------------------------------LREQS Q6P949_DANRE Q6P949_DANRE EGVIPEKKPSSLAALESHAKDILNKMDQPKKLIKTGMSIMEKETNKPNDVKKFEMIREHN MATCH CONSENSUS ????????????????????????????????????????????????????????????

A5PL83_DANRE A5PL83_DANRE AFSSKVNGKFKKVCPVPAAAVE-----------ASHDNALRLVMCNGKIIRERMPITNVA Q5RHD1_DANRE Q5RHD1_DANRE AFSSKVNGKFKKVCPVPAAAVE-----------ASHDNALRLVMCNGKIIRERMPITNVA Q08D35_XENTR Q08D35_XENTR AGTYKLNMRFNKPLLPSSTEPD----------QKVRDNGIRLLLSNGRIIRDERQPFTDR A4D1S9_HUMAN A4D1S9_HUMAN ILSSKLNGKFNKHLQPSSTVPE---------WRAK-DNDLRLLLTNGRIIKDERQPFADQ JHD1D_HUMAN JHD1D_HUMAN ILSSKLNGKFNKHLQPSSTVPE---------WRAK-DNDLRLLLTNGRIIKDERQPFADQ A6H6E5_MOUSE A6H6E5_MOUSE LLSSKLNGKFNKHLQPSSTVPE---------WRAK-DNDLRLLLTNGRIIKDERQLFADR JHD1D_MOUSE JHD1D_MOUSE LLSSKLNGKFNKHLQPSSTVPE---------WRAK-DNDLRLLLTNGRIIKDERQLFADR B9EKK1_MOUSE B9EKK1_MOUSE LQNVEFNITSTCLNDSDDNSKHD------KAFNGN-ESLVPLLMANGNT----KREKSLS B6D5P9_PERLE B6D5P9_PERLE ------------------------------------------------------------ B6D5P7_PERPL B6D5P7_PERPL ------------------------------------------------------------ B6D5P8_PERMA B6D5P8_PERMA ------------------------------------------------------------ B6D5Q0_PERER B6D5Q0_PERER ------------------------------------------------------------ B6D5Q1_PERCA B6D5Q1_PERCA ------------------------------------------------------------ Q28G38_XENTR Q28G38_XENTR QHHKKFGSSGKEMEDTSLDPLEEKPDVGLLDGDMA-DSKFRLMMANGTNLSGKKERVGAG Q7T0U8_XENLA Q7T0U8_XENLA ------------------------------------------------------------ Q5JPS0_HUMAN Q5JPS0_HUMAN FQKAKFNITGACLNDSDDDSPD-------LDLDGN-ESPLALLMSNGST----KRVKSLS Q5JPS3_HUMAN Q5JPS3_HUMAN FQKAKFNITGACLNDSDDDSPD-------LDLDGN-ESPLALLMSNGST----KRVKSLS PHF8_HUMAN PHF8_HUMAN FQKAKFNITGACLNDSDDDSPD-------LDLDGN-ESPLALLMSNGST----KRVKSLS B7Z911_HUMAN B7Z911_HUMAN -----FNITGACLNDSDDDSPD-------LDLDGN-ESPLALLMSNGST----KRVKSLS Q5JPS2_HUMAN Q5JPS2_HUMAN FQKAKFNITGACLNDSDDDSPD-------LDLDGN-ESPLALLMSNGST----KRVKSLS Q5JPR9_HUMAN Q5JPR9_HUMAN FQKAKFNITGACLNDSDDDSPD-------LDLDGN-ESPLALLMSNGST----KRVKSLS A2ABV1_MOUSE A2ABV1_MOUSE SQKAKFNMSGTSLNDSDDDSAD-------MDLDGS-ENPLALLMANGS------------ Q3UZ32_MOUSE Q3UZ32_MOUSE SQKAKFNMSGTSLNDSDDDSAD-------MDLDGS-ENPLALLMANGS------------ A2ABV3_MOUSE A2ABV3_MOUSE -----FNMSGTSLNDSDDDSAD-------MDLDGS-ENPLALLMANGST----KRMKSVS A2ABV2_MOUSE A2ABV2_MOUSE SQKAKFNMSGTSLNDSDDDSAD-------MDLDGS-ENPLALLMANGST----KRMKSVS A2ABU8_MOUSE A2ABU8_MOUSE SQKAKFNMSGTSLNDSDDDSAD-------MDLDGS-ENPLALLMANGST----KRMKSVS PHF8_MOUSE PHF8_MOUSE SQKAKFNMSGTSLNDSDDDSAD-------MDLDGS-ENPLALLMANGST----KRMKSVS PHF2_HUMAN PHF2_HUMAN KSKSEAKWKYKNSKPDSLLKMEEEQKLEKSPLAGNKDNKFSFSFSNKKL----LGSKALR PHF2_MOUSE PHF2_MOUSE KSKSEAKWKYKNSKPDSLLKMEEEQRLEKSPLAGN-KDKFSFSFSNRKL----LGSKALR Q6A023_MOUSE Q6A023_MOUSE KSKSEAKWKYKNSKPDSLLKMEEEQRLEKSPLAGN-KDKFSFSFSNRKL----LGSKALR Q4STN5_TETNG Q4STN5_TETNG KNKTEAKWKYKNSKPDSLLKMEEESKVDRTPLSSN-KDKFSFTMSHKKM----LSSKILK Q6P949_DANRE Q6P949_DANRE KNKTESKWKYKNSKPDSLLKMEEEHKFDKSLLSHK-DNKFAFSLSNKKL----LGSKMLK MATCH CONSENSUS ????????????????????????????????????????????????????????????

A5PL83_DANRE A5PL83_DANRE ATVNA-------------------------------------------------LEMYHK Q5RHD1_DANRE Q5RHD1_DANRE ATVNA-------------------------------------------------VEMYHK Q08D35_XENTR Q08D35_XENTR SLYTADSEDEDDRARSRKAKDIKQEKPCSTSG----------MEDKAETQKPLNMFFESV A4D1S9_HUMAN A4D1S9_HUMAN SLYTADSENEEDKRRTKKAKMKIEESSGVEGV------------EHEESQKPLNGFFTRV JHD1D_HUMAN JHD1D_HUMAN SLYTADSENEEDKRRTKKAKMKIEESSGVEGV------------EHEESQKPLNGFFTRV A6H6E5_MOUSE A6H6E5_MOUSE SLYTADSENEEDKKPTQNANMKTEQSSGREEA------------ESQGSPKPLNRIFTSV JHD1D_MOUSE JHD1D_MOUSE SLYTADSENEEDKKPTQNANMKTEQSSGREEA------------ESQGSPKPLNRIFTSV B9EKK1_MOUSE B9EKK1_MOUSE ESWQAKITKKEDTSRLMKEQAMVDTFDLDLND--------ELQIEKGLGKEKVSLVVRPK B6D5P9_PERLE B6D5P9_PERLE ------------------------------------------------------------ B6D5P7_PERPL B6D5P7_PERPL ------------------------------------------------------------ B6D5P8_PERMA B6D5P8_PERMA ------------------------------------------------------------ B6D5Q0_PERER B6D5Q0_PERER ------------------------------------------------------------ B6D5Q1_PERCA B6D5Q1_PERCA ------------------------------------------------------------ Q28G38_XENTR Q28G38_XENTR GRRQAAANRHIKKEQLQADLSSGDPFLLDSED--------DLQIDETPR----------- Q7T0U8_XENLA Q7T0U8_XENLA ------------------------------------------------------------ Q5JPS0_HUMAN Q5JPS0_HUMAN KSRRTKIAKKVDKARLMAEQVMEDEFDLDSDD--------ELQIDERLGKEKATLIIRPK Q5JPS3_HUMAN Q5JPS3_HUMAN KSRRTKIAKKVDKARLMAEQVMEDEFDLDSDD--------ELQIDERLGKEKATLIIRPK PHF8_HUMAN PHF8_HUMAN KSRRTKIAKKVDKARLMAEQVMEDEFDLDSDD--------ELQIDERLGKEKATLIIRPK B7Z911_HUMAN B7Z911_HUMAN KSRRTKIAKKVDKARLMAEQVMEDEFDLDSDD--------ELQIDERLGKEKATLIIRPK Q5JPS2_HUMAN Q5JPS2_HUMAN KSRRTKIAKKVDKARLMAEQVMEDEFDLDSDD--------ELQIDERLGKEKATLIIRPK Q5JPR9_HUMAN Q5JPR9_HUMAN KSRRTKIAKKVDKARLMAEQVMEDEFDLDSDD--------ELQIDERLGKEKATLIIRPK A2ABV1_MOUSE A2ABV1_MOUSE ------------------------------------------------------LFIW-- Q3UZ32_MOUSE Q3UZ32_MOUSE ------------------------------------------------------LFIW-- A2ABV3_MOUSE A2ABV3_MOUSE KSRRAKIAKKVDSARLVAEQVMGDEFDLDSDD--------ELQIDERLGKEKANLLIRSK A2ABV2_MOUSE A2ABV2_MOUSE KSRRAKIAKKVDSARLVAEQVMGDEFDLDSDD--------ELQIDERLGKEKANLLIRSK A2ABU8_MOUSE A2ABU8_MOUSE KSRRAKIAKKVDSARLVAEQVMGDEFDLDSDD--------ELQIDERLGKEKANLLIRSK PHF8_MOUSE PHF8_MOUSE KSRRAKIAKKVDSARLVAEQVMGDEFDLDSDD--------ELQIDERLGKEKANLLIRSK PHF2_HUMAN PHF2_HUMAN PPTSPGVFGALQNFKEDKPKPVRDEYEYVSDDGELKIDEFPIRRKKNAPKRDLSFLLDKK PHF2_MOUSE PHF2_MOUSE PPSSPGVFGALQSFKEDKAKPVRDEYEYVSDDGELKIDEFPIRRKKSAPKRDLSFLLDKK Q6A023_MOUSE Q6A023_MOUSE PPSSPGVFGALQSFKEDKAKPVRDEYEYVSDDGELKIDEFPIRRKKSAPKRDLSFLLDKK Q4STN5_TETNG Q4STN5_TETNG PQMNSSVFGSLQNLKDTKSKPVRDEYEYVSDEGELKIDEFPIRRKKNSARRDQSFFSEVR Q6P949_DANRE Q6P949_DANRE TQTNSSVFGSIQNIKEEKPKPVRDEYEYVSDEGELKIEEFPIRRKKNAVKREFSFLSNIK MATCH CONSENSUS ????????????????????????????????????????????????????????????

A5PL83_DANRE A5PL83_DANRE HRMKLERIPMCPEEKVKKKKKK-------------------------------------- Q5RHD1_DANRE Q5RHD1_DANRE HRIKLERIPMCPEEKVKKEK---------------------------------------- Q08D35_XENTR Q08D35_XENTR KSELRNGSSEYSDISDSEGSEDNCTNQKHFSEESESSGDDDDEEEEEEEERQEPIRNLKE A4D1S9_HUMAN A4D1S9_HUMAN KSELRSRSSGYSDISESEDSGPECTALKSIFTTEESESSGDEKKQEITSNFKEESNVMRN JHD1D_HUMAN JHD1D_HUMAN KSELRSRSSGYSDISESEDSGPECTALKSIFTTEESESSGDEKKQEITSNFKEESNVMRN A6H6E5_MOUSE A6H6E5_MOUSE RSELRSRPSEYSDGSDSEDSGPDCTALKINFATEDSESSGDEKKHEITSHFKEESDIVRN JHD1D_MOUSE JHD1D_MOUSE RSELRSRPSEYSDGSDSEDSGPDCTALKINFATEDSESSGDEKKHEITSHFKEESDIVRN B9EKK1_MOUSE B9EKK1_MOUSE IPPSLPHVKLCSDQNQSHDPGETEITIVENYKIDKEMVEGVEG-K-FKNG--SESGGTID B6D5P9_PERLE B6D5P9_PERLE ------------------------------------------------------------ B6D5P7_PERPL B6D5P7_PERPL ------------------------------------------------------------ B6D5P8_PERMA B6D5P8_PERMA ------------------------------------------------------------ B6D5Q0_PERER B6D5Q0_PERER ------------------------------------------------------------ B6D5Q1_PERCA B6D5Q1_PERCA ------------------------------------------------------------ Q28G38_XENTR Q28G38_XENTR ------------------------------------------------------------ Q7T0U8_XENLA Q7T0U8_XENLA ------------------------------------------------------------ Q5JPS0_HUMAN Q5JPS0_HUMAN FPRKLPRAKPCSDPNRVREPGEVEFDIEEDYTTDEDMVEGVEGYQ-TATP--APAQGA-- Q5JPS3_HUMAN Q5JPS3_HUMAN FPRKLPRAKPCSDPNRVREPGEVEFDIEEDYTTDEDMVEGVEG-K-LGNG--SGAGGILD PHF8_HUMAN PHF8_HUMAN FPRKLPRAKPCSDPNRVREPGEVEFDIEEDYTTDEDMVEGVEG-K-LGNG--SGAGGILD B7Z911_HUMAN B7Z911_HUMAN FPRKLPRAKPCSDPNRVREPGEVEFDIEEDYTTDEDMVEGVEG-K-LGNG--SGAGGILD Q5JPS2_HUMAN Q5JPS2_HUMAN FPRKLPRAKPCSDPNRVREPGEVEFDIEEDYTTDEDMVEGVEG-K-LGNG--SGAGGILD Q5JPR9_HUMAN Q5JPR9_HUMAN FPRKLPRAKPCSDPNRVREPGEVEFDIEEDYTTDEDMVEGVEG-K-LGNG--SGAGGILD A2ABV1_MOUSE A2ABV1_MOUSE ---------------------------------------------------------LIT Q3UZ32_MOUSE Q3UZ32_MOUSE ---------------------------------------------------------LIT A2ABV3_MOUSE A2ABV3_MOUSE FPRKLPRAKPCSDPNRIREPGEVEFDIEEDYTTDEDMVEGVES-K-LGNG--SGAGGILD A2ABV2_MOUSE A2ABV2_MOUSE FPRKLPRAKPCSDPNRIREPGEVEFDIEEDYTTDEDMVEGVES-K-LGNG--SGAGGILD A2ABU8_MOUSE A2ABU8_MOUSE FPRKLPRAKPCSDPNRIREPGEVEFDIEEDYTTDEDMVEGVES-K-LGNG--SGAGGILD PHF8_MOUSE PHF8_MOUSE FPRKLPRAKPCSDPNRIREPGEVEFDIEEDYTTDEDMVEGVES-K-LGNG--SGAGGILD PHF2_HUMAN PHF2_HUMAN AVLPTPVTKPKLDSAAYKSDDSSD---EGSLHIDTDTKPGRNARVKKESG--SSAAGILD PHF2_MOUSE PHF2_MOUSE EALLMPTSKPKLDSAVYKSDDSSD---EGSLHIDTDTKPGRNAKVKKESG--SSAAGILD Q6A023_MOUSE Q6A023_MOUSE EALLMPTSKPKLDSAVYKSDDSSD---EGSLHIDTDTKPGRNAKVKKESG--SSAAGILD Q4STN5_TETNG Q4STN5_TETNG EPIQ-PTKKAKLQPSVTRTAESSDEEMLHIDTESKPEVKGSGLKVRKKDH---SAAGILD Q6P949_DANRE Q6P949_DANRE EPIQ-PSKKPKLPPSDMKSPDTSDEESLHIDTEAKTDVKGRNSKVSKKKG--GSSAGILD MATCH CONSENSUS ????????????????????????????????????????????????????????????

A5PL83_DANRE A5PL83_DANRE ------------------------------------------------------------ Q5RHD1_DANRE Q5RHD1_DANRE ------------------------------------------------------------ Q08D35_XENTR Q08D35_XENTR EHSGRRLPCDPNFPWPDHDSPQKRECPTSTSMEQEAVQGMLSMASLHYPSALPTP----- A4D1S9_HUMAN A4D1S9_HUMAN FLQKSQKPSRSEI-------PIKRECPTSTSTEEEAIQGMLSMAGLHYSTC--------- JHD1D_HUMAN JHD1D_HUMAN FLQKSQKPSRSEI-------PIKRECPTSTSTEEEAIQGMLSMAGLHYSTC--------- A6H6E5_MOUSE A6H6E5_MOUSE LLQKSQKPSRQEI-------PVKRECPTSTSTEEEAIQGMLSMAGLHYSSC--------- JHD1D_MOUSE JHD1D_MOUSE LLQKSQKPSRQEI-------PVKRECPTSTSTEEEAIQGMLSMAGLHYSSC--------- B9EKK1_MOUSE B9EKK1_MOUSE PLKTKKQVGGPGC-------VILTDDPNSSSN-KKDIQDTVCMSDLQSSPPSQAPSSLQA B6D5P9_PERLE B6D5P9_PERLE ------------------------------------------------------------ B6D5P7_PERPL B6D5P7_PERPL ------------------------------------------------------------ B6D5P8_PERMA B6D5P8_PERMA ------------------------------------------------------------ B6D5Q0_PERER B6D5Q0_PERER ------------------------------------------------------------ B6D5Q1_PERCA B6D5Q1_PERCA ------------------------------------------------------------ Q28G38_XENTR Q28G38_XENTR ------------------------------------------------------------ Q7T0U8_XENLA Q7T0U8_XENLA ------------------------------------------------------------ Q5JPS0_HUMAN Q5JPS0_HUMAN -----------------------SEAPASPST-QEAIQGMLCMANLQSSSSSPATSSLQA Q5JPS3_HUMAN Q5JPS3_HUMAN LLKASRQVGGPDY-------AALTEAPASPST-QEAIQGMLCMANLQSSSSSPATSSLQA PHF8_HUMAN PHF8_HUMAN LLKASRQVGGPDY-------AALTEAPASPST-QEAIQGMLCMANLQSSSSSPATSSLQA B7Z911_HUMAN B7Z911_HUMAN LLKASRQVGGPDY-------AALTEAPASPST-QEAIQGMLCMANLQSSSSSPATSSLQA Q5JPS2_HUMAN Q5JPS2_HUMAN LLKASRQVGGPDY-------AALTEAPASPST-QEAIQGMLCMANLQSSSSSPATSSLQA Q5JPR9_HUMAN Q5JPR9_HUMAN LLKASRQVGGPDY-------AALTEAPASPST-QEAIQGMLCMANLQSSSSSPATSSLQA A2ABV1_MOUSE A2ABV1_MOUSE LM---------DF-------CILNHS---------------CI----------------- Q3UZ32_MOUSE Q3UZ32_MOUSE LM---------DF-------CILNHS---------------CI----------------- A2ABV3_MOUSE A2ABV3_MOUSE LLKASRQVGGPDY-------AALTEAPASPST-QEAIQGMLCMANLQSSSSSPATSSLQA A2ABV2_MOUSE A2ABV2_MOUSE LLKASRQVGGPDY-------AALTEAPASPST-QEAIQGMLCMANLQSSSSSPATSSLQA A2ABU8_MOUSE A2ABU8_MOUSE LLKASRQVGGPDY-------AALTEAPASPST-QEAIQGMLCMANLQSSSSSPATSSLQA PHF8_MOUSE PHF8_MOUSE LLKASRQVGGPDY-------AALTEAPASPST-QEAIQGMLCMANLQSSSSSPATSSLQA PHF2_HUMAN PHF2_HUMAN LLQASEEVGALEY-------NPSSQPPASPST-QEAIQGMLSMANLQASDSCLQTTW--- PHF2_MOUSE PHF2_MOUSE LLQASEEVGALEY-------NPNSQPPASPST-QEAIQGMLSMANLQASDSCLQTTWGTG Q6A023_MOUSE Q6A023_MOUSE LLQASEEVGALEY-------NPNSQPPASPST-QEAIQGMLSMANLQASDSCLQTTWGTG Q4STN5_TETNG Q4STN5_TETNG LLQASKQVGGIDY-------GTNSQPPASPST-QEAIQGMLSMANLPSSESLQQPWSNSQ Q6P949_DANRE Q6P949_DANRE LLQASKQVGGIDY-------SNNSQPPASPST-QEAIQGMLSMANLQSSDSC-----LQP MATCH CONSENSUS ????????????????????????????????????????????????????????????

A5PL83_DANRE A5PL83_DANRE ------------------------------------------------------------ Q5RHD1_DANRE Q5RHD1_DANRE ------------------------------------------------------------ Q08D35_XENTR Q08D35_XENTR -----------AKSTDCNIRGGYPQLHIRVSQGNGKEHLDSHSHKAANSDHHVKDEGEFS A4D1S9_HUMAN A4D1S9_HUMAN -----LQRQI-QSTDCSGERNSLQDPSSCHGSNHEVRQLYRYDKPVECGYHVKTEDPDLR JHD1D_HUMAN JHD1D_HUMAN -----LQRQI-QSTDCSGERNSLQDPSSCHGSNHEVRQLYRYDKPVECGYHVKTEDPDLR A6H6E5_MOUSE A6H6E5_MOUSE -----LQRQI-QSTDCSGEKNSLQDPSSCHGSNPEFRQLYRCNKPVEFGYHAKTEDQDLM JHD1D_MOUSE JHD1D_MOUSE -----LQRQI-QSTDCSGEKNSLQDPSSCHGSNPEFRQLYRCNKPVEFGYHAKTEDQDLM B9EKK1_MOUSE B9EKK1_MOUSE FWSGGQDQGNKSPSSVLGTVSDSPVSRRTPRKWPIKRLAYWRNES--EAGNA-CVDEQGS B6D5P9_PERLE B6D5P9_PERLE ------------------------------------------------------------ B6D5P7_PERPL B6D5P7_PERPL ------------------------------------------------------------ B6D5P8_PERMA B6D5P8_PERMA ------------------------------------------------------------ B6D5Q0_PERER B6D5Q0_PERER ------------------------------------------------------------ B6D5Q1_PERCA B6D5Q1_PERCA ------------------------------------------------------------ Q28G38_XENTR Q28G38_XENTR ------------------------------------------------------------ Q7T0U8_XENLA Q7T0U8_XENLA ------------------------------------------------------------ Q5JPS0_HUMAN Q5JPS0_HUMAN WWTGGQDRSSGSSSSGLGTVSNSPASQRTPGKRPIKRPAYWRTESEEEEENA-SLDEQDS Q5JPS3_HUMAN Q5JPS3_HUMAN WWTGGQDRSSGSSSSGLGTVSNSPASQRTPGKRPIKRPAYWRTESEEEEENA-SLDEQDS PHF8_HUMAN PHF8_HUMAN WWTGGQDRSSGSSSSGLGTVSNSPASQRTPGKRPIKRPAYWRTESEEEEENA-SLDEQDS B7Z911_HUMAN B7Z911_HUMAN WWTGGQDRSSGSSSSGLGTVSNSPASQRTPGKRPIKRPAYWRTESEEEEENA-SLDEQDS Q5JPS2_HUMAN Q5JPS2_HUMAN WWTGGQDRSSGSSSSGLGTVSNSPASQRTPGKRPIKRPAYWRTESEEEEENA-SLDEQDS Q5JPR9_HUMAN Q5JPR9_HUMAN WWTGGQDRSSGSSSSGLGTVSNSPASQRTPGKRPIKRPAYWRTESEEEEENA-SLDEQDS A2ABV1_MOUSE A2ABV1_MOUSE -----------------------------PGMKPT------------------------- Q3UZ32_MOUSE Q3UZ32_MOUSE -----------------------------PGMKPT------------------------- A2ABV3_MOUSE A2ABV3_MOUSE WWTGGQERSSGSSSSGLGTVSSSPASQRTPGKRPIKRPAYWKNES-EEEENA-SLDEQDS A2ABV2_MOUSE A2ABV2_MOUSE WWTGGQERSSGSSSSGLGTVSSSPASQRTPGKRPIKRPAYWKNES-EEEENA-SLDEQDS A2ABU8_MOUSE A2ABU8_MOUSE WWTGGQERSSGSSSSGLGTVSSSPASQRTPGKRPIKRPAYWKNES-EEEENA-SLDEQDS PHF8_MOUSE PHF8_MOUSE WWTGGQERSSGSSSSGLGTVSSSPASQRTPGKRPIKRPAYWKNES-EEEENA-SLDEQDS PHF2_HUMAN PHF2_HUMAN ----GAGQAKGSSLAAHGARKNGGGSGKSAGKRLLKRAAKNSVDLDD------YEEEQDH PHF2_MOUSE PHF2_MOUSE QAKGGSLAAHGARKIGGGNKGTGKRLLKRTAKNSVDLEDY---------------EEQDH Q6A023_MOUSE Q6A023_MOUSE QAKGGSLAAHGARKIGGGNKGTGKRLLKRTAKNSVDLEDY---------------EEQDH Q4STN5_TETNG Q4STN5_TETNG SKNSSQLKNN-SYGAQAGKKAGGGFGSGGDTKRPTKHLCKKSRKSSSVESQD-YDDDQDH Q6P949_DANRE Q6P949_DANRE FWSNSQAKNN-SHSSAASKKPSRAAGAGGNSKRPAKRLPKKTQKSSSVDSSDMFDDDQDH MATCH CONSENSUS ????????????????????????????????????????????????????????????

A5PL83_DANRE A5PL83_DANRE ------------------------------------------------------------ Q5RHD1_DANRE Q5RHD1_DANRE ------------------------------------------------------------ Q08D35_XENTR Q08D35_XENTR ALDWIRQPDASCRLSPQDSCQV----------PQSLRREFAHEEYEKAPEDKHY--LEIE A4D1S9_HUMAN A4D1S9_HUMAN TSSWIKQFD-TSRFHPQD--------------LSRSQKCIRKEGSSEISQRVQS--RNYV JHD1D_HUMAN JHD1D_HUMAN TSSWIKQFD-TSRFHPQD--------------LSRSQKCIRKEGSSEISQRVQS--RNYV A6H6E5_MOUSE A6H6E5_MOUSE TSSWNKQFDRTSRFNAQD--------------LSRSQKHIKKESSSEINQKAQS--RHCV JHD1D_MOUSE JHD1D_MOUSE TSSWNKQFDRTSRFNAQD--------------LSRSQKHIKKESSSEINQKAQS--RHCV B9EKK1_MOUSE B9EKK1_MOUSE LGACFKEAKYIFLSLESDDDDDDDDDDDDDNNPALRVLPKKRKISDNAPRIPRA--DEIP B6D5P9_PERLE B6D5P9_PERLE ------------------------------------------------------------ B6D5P7_PERPL B6D5P7_PERPL ------------------------------------------------------------ B6D5P8_PERMA B6D5P8_PERMA ------------------------------------------------------------ B6D5Q0_PERER B6D5Q0_PERER ------------------------------------------------------------ B6D5Q1_PERCA B6D5Q1_PERCA ------------------------------------------------------------ Q28G38_XENTR Q28G38_XENTR ------------------------------------------------------------ Q7T0U8_XENLA Q7T0U8_XENLA ------------------------------------------------------------ Q5JPS0_HUMAN Q5JPS0_HUMAN LGACFKDAEYIYPSLESDDDD-----------PALKSRPKKKKNSDDAPWSPKA--RVTP Q5JPS3_HUMAN Q5JPS3_HUMAN LGACFKDAEYIYPSLESDDDD-----------PALKSRPKKKKNSDDAPWSPKA--RVTP PHF8_HUMAN PHF8_HUMAN LGACFKDAEYIYPSLESDDDD-----------PALKSRPKKKKNSDDAPWSPKA--RVTP B7Z911_HUMAN B7Z911_HUMAN LGACFKDAEYIYPSLESDDDD-----------PALKSRPKKKKNSDDAPWSPKA--RVTP Q5JPS2_HUMAN Q5JPS2_HUMAN LGACFKDAEYIYPSLESDDDD-----------PALKSRPKKKKNSDDAPWSPKA--RVTP Q5JPR9_HUMAN Q5JPR9_HUMAN LGACFKDAEYIYPSLESDDDD-----------PALKSRPKKKKNSDDAPWSPKA--RVTP A2ABV1_MOUSE A2ABV1_MOUSE ------------------------------------------------------------ Q3UZ32_MOUSE Q3UZ32_MOUSE ------------------------------------------------------------ A2ABV3_MOUSE A2ABV3_MOUSE LGACFKDAEYIYPSLESDDDD-----------PALKSRPKKKKNSDDAPWSPKA--RVTP A2ABV2_MOUSE A2ABV2_MOUSE LGACFKDAEYSKNMLEY------------------------------------------- A2ABU8_MOUSE A2ABU8_MOUSE LGACFKDAEYIYPSLESDDDD-----------PALKSRPKKKKNSDDAPWSPKA--RVTP PHF8_MOUSE PHF8_MOUSE LGACFKDAEYIYPSLESDDDD-----------PALKSRPKKKKNSDDAPWSPKA--RVTP PHF2_HUMAN PHF2_HUMAN LDACFKDSDYVYPSLESDEDN-----------PIFKSRSKKRKGSDDAPYSPTA--RVGP PHF2_MOUSE PHF2_MOUSE LDACFKDSDYVYPSLESDEDN-----------PVFKSRSKKRKGSDDAPYSPTA--RVGP Q6A023_MOUSE Q6A023_MOUSE LDACFKDSDYVYPSLESDEDN-----------PVFKSRSKKRKGSDDAPYSPTA--RVGP Q4STN5_TETNG Q4STN5_TETNG LEACFRDSDYVYPSLESEEDN-----------PVFKSRSKKRKSSDDTPYNPTVSHQVRP Q6P949_DANRE Q6P949_DANRE LEACFKDSDYVYPSLESEEDN-----------PIFKSRSKKKKKK--------------- MATCH CONSENSUS ????????????????????????????????????????????????????????????

A5PL83_DANRE A5PL83_DANRE ------------------------------------------------------------ Q5RHD1_DANRE Q5RHD1_DANRE ------------------------------------------------------------ Q08D35_XENTR Q08D35_XENTR HWDSAEYQPEKYDPESSMSSGECHLSDGSLSPTRIYGDTAAAVPLHPTKRPASNPPPISN A4D1S9_HUMAN A4D1S9_HUMAN DSSGSSLQNGKYMQNSNLTSGACQISNGSLSPERPVGETSFSVPLHPTKRPASNPPPISN JHD1D_HUMAN JHD1D_HUMAN DSSGSSLQNGKYMQNSNLTSGACQISNGSLSPERPVGETSFSVPLHPTKRPASNPPPISN A6H6E5_MOUSE A6H6E5_MOUSE DSNSSSIQNGKYTLNPSLVS--CQISNGSLSPERPIGETSFSMPLHPTKRPASNPPPISN JHD1D_MOUSE JHD1D_MOUSE DSNSSSIQNGKYTLNPSLVS--CQISNGSLSPERPIGETSFSMPLHPTKRPASNPPPISN B9EKK1_MOUSE B9EKK1_MOUSE TLPKQDHSVPEGNRVGSIEIDWTTAATKLAQEVNNMKLTLTSPGKSSQ------------ B6D5P9_PERLE B6D5P9_PERLE ------------------------------------------------------------ B6D5P7_PERPL B6D5P7_PERPL ------------------------------------------------------------ B6D5P8_PERMA B6D5P8_PERMA ------------------------------------------------------------ B6D5Q0_PERER B6D5Q0_PERER ------------------------------------------------------------ B6D5Q1_PERCA B6D5Q1_PERCA ------------------------------------------------------------ Q28G38_XENTR Q28G38_XENTR ------------------------------------------------------------ Q7T0U8_XENLA Q7T0U8_XENLA ------------------------------------------------------------ Q5JPS0_HUMAN Q5JPS0_HUMAN TLPKQDRPVREGTRVASIETGLAAAAAKLAQQ----------VKKMKL------------ Q5JPS3_HUMAN Q5JPS3_HUMAN TLPKQDRPVREGTRVASIETGLAAAAAKLAQQ----------VKKMKL------------ PHF8_HUMAN PHF8_HUMAN TLPKQDRPVREGTRVASIETGLAAAAAKLAQQELQKAQKKKYIKKKPLLKEVEQPRPQDS B7Z911_HUMAN B7Z911_HUMAN TLPKQDRPVREGTRVASIETGLAAAAAKLAQQELQKAQKKKYIKKKPLLKEVEQPRPQDS Q5JPS2_HUMAN Q5JPS2_HUMAN TLPKQDRPVREGTRVASIETGLAAAAAKLAQQELQKAQKKKYIKKKPLLKEVEQPRPQDS Q5JPR9_HUMAN Q5JPR9_HUMAN TLPKQDRPVREGTRVASIETGLAAAAAKLAQQELQKAQKKKYIKKKPLLKEVEQPRPQDS A2ABV1_MOUSE A2ABV1_MOUSE ------------------------------------------------------------ Q3UZ32_MOUSE Q3UZ32_MOUSE ------------------------------------------------------------ A2ABV3_MOUSE A2ABV3_MOUSE TLPKQDRPVREGTRVASIETGLAAAAAKLAQQV--------------------------- A2ABV2_MOUSE A2ABV2_MOUSE ------------------------------------------------------------ A2ABU8_MOUSE A2ABU8_MOUSE TLPKQDRPVREGTRVASIETGLAAAAAKLAQQELQKAQKKKYIKKKPLLKEVEQPRPQDS PHF8_MOUSE PHF8_MOUSE TLPKQDRPVREGTRVASIETGLAAAAAKLAQQELQKAQKKKYIKKKPLLKEVEQPRPQDS PHF2_HUMAN PHF2_HUMAN SVPRQDRPVREGTRVASIETGLAAAAAKLSQQEEQKSKKKKSAKRKLTPNTTSPSTSTSI PHF2_MOUSE PHF2_MOUSE SVPRQDRPVREGTRVASIETGLAAAAAKLSQQEEQKNRKKKNTKRKPAPNTASPSISTSA Q6A023_MOUSE Q6A023_MOUSE SVPRQDRPVREGTRVASIETGLAAAAAKLSQQEEQKNRKKKNTKRKPASNTASPSISTSA Q4STN5_TETNG Q4STN5_TETNG AFASPREQYRADAHLHTVSQQEEQKSKKKRKSAKRKVMEHRQSNSRDSSSPEPHLESQDD Q6P949_DANRE Q6P949_DANRE ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

A5PL83_DANRE A5PL83_DANRE ------------------------------------------------------------ Q5RHD1_DANRE Q5RHD1_DANRE ------------------------------------------------------------ Q08D35_XENTR Q08D35_XENTR ------------------------------------------------------------ A4D1S9_HUMAN A4D1S9_HUMAN ------------------------------------------------------------ JHD1D_HUMAN JHD1D_HUMAN ------------------------------------------------------------ A6H6E5_MOUSE A6H6E5_MOUSE ------------------------------------------------------------ JHD1D_MOUSE JHD1D_MOUSE ------------------------------------------------------------ B9EKK1_MOUSE B9EKK1_MOUSE ------------------------------------------------------------ B6D5P9_PERLE B6D5P9_PERLE ------------------------------------------------------------ B6D5P7_PERPL B6D5P7_PERPL ------------------------------------------------------------ B6D5P8_PERMA B6D5P8_PERMA ------------------------------------------------------------ B6D5Q0_PERER B6D5Q0_PERER ------------------------------------------------------------ B6D5Q1_PERCA B6D5Q1_PERCA ------------------------------------------------------------ Q28G38_XENTR Q28G38_XENTR ------------------------------------------------------------ Q7T0U8_XENLA Q7T0U8_XENLA ------------------------------------------------------------ Q5JPS0_HUMAN Q5JPS0_HUMAN ------------------------------------SLTDSG------------------ Q5JPS3_HUMAN Q5JPS3_HUMAN ------------------------------------SLTDSG------------------ PHF8_HUMAN PHF8_HUMAN NLSLTVPAPTVAATPQLVTSSSPLPPPEPKQEALSGSLADHEYTARP------------- B7Z911_HUMAN B7Z911_HUMAN NLSLTVPAPTVAATPQLVTSSSPLPPPEPKQEALSGSLADHEYTARP------------- Q5JPS2_HUMAN Q5JPS2_HUMAN NLSLTVPAPTVAATPQLVTSSSPLPPPEPKQEALSGSLADHEYTARP------------- Q5JPR9_HUMAN Q5JPR9_HUMAN NLSLTVPAPTVAATPQLVTSSSPLPPPEPKQEALSGSLADHEYTARP------------- A2ABV1_MOUSE A2ABV1_MOUSE ------------------------------------------------------------ Q3UZ32_MOUSE Q3UZ32_MOUSE ------------------------------------------------------------ A2ABV3_MOUSE A2ABV3_MOUSE ------------------------------------------------------------ A2ABV2_MOUSE A2ABV2_MOUSE ------------------------------------------------------------ A2ABU8_MOUSE A2ABU8_MOUSE NPIMTMPAPTVATTPQPDTSSSPQPPPEPKQEALSGSLADHEYTARP------------- PHF8_MOUSE PHF8_MOUSE NPIMTMPAPTVATTPQPDTSSSPQPPPEPKQEALSGSLADHEYTARP------------- PHF2_HUMAN PHF2_HUMAN -------SAGTTSTSTTPASTTPASTTPASTSTASSQASQEGSSPEPPPESHSSSLADHE PHF2_MOUSE PHF2_MOUSE SASTGTTSASTTPASTTPASTTPASTTPASTSTASSQASQEGSSPEPPPESHSSSLADHE Q6A023_MOUSE Q6A023_MOUSE SASTGTTSASTTPASTTPASTTPASTTPASTSTASSQASQEGSSPEPPPESHSSSLADHE Q4STN5_TETNG Q4STN5_TETNG SLSDFALSAETVRAPEGSKPMAPGVFLHHKQSSLHSPSSNHHSAKST------------- Q6P949_DANRE Q6P949_DANRE ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

A5PL83_DANRE A5PL83_DANRE ------------------------------------------------------------ Q5RHD1_DANRE Q5RHD1_DANRE ------------------------------------------------------------ Q08D35_XENTR Q08D35_XENTR --------------------------------------QATKGKRPKKGMATAKQRLGKI A4D1S9_HUMAN A4D1S9_HUMAN --------------------------------------QATKGKRPKKGMATAKQRLGKI JHD1D_HUMAN JHD1D_HUMAN --------------------------------------QATKGKRPKKGMATAKQRLGKI A6H6E5_MOUSE A6H6E5_MOUSE --------------------------------------QATKGKRPKKGMATAKQRLGKI JHD1D_MOUSE JHD1D_MOUSE --------------------------------------QATKGKRPKKGMATAKQRLGKI B9EKK1_MOUSE B9EKK1_MOUSE ------------------------------------------------------------ B6D5P9_PERLE B6D5P9_PERLE ------------------------------------------------------------ B6D5P7_PERPL B6D5P7_PERPL ------------------------------------------------------------ B6D5P8_PERMA B6D5P8_PERMA ------------------------------------------------------------ B6D5Q0_PERER B6D5Q0_PERER ------------------------------------------------------------ B6D5Q1_PERCA B6D5Q1_PERCA ------------------------------------------------------------ Q28G38_XENTR Q28G38_XENTR ------------------------------------------------------------ Q7T0U8_XENLA Q7T0U8_XENLA ------------------------------------------------------------ Q5JPS0_HUMAN Q5JPS0_HUMAN ------------------------------------------------------------ Q5JPS3_HUMAN Q5JPS3_HUMAN ------------------------------------------------------------ PHF8_HUMAN PHF8_HUMAN ----NAFGMAQANRSTTPMAPGVFLTQRRPSVGSQSN-QAGQGKRPKKGLATAKQRLGRI B7Z911_HUMAN B7Z911_HUMAN ----NAFGMAQANRSTTPMAPGVFLTQRRPSVGSQSN-QAGQGKRPKKGLATAKQRLGRI Q5JPS2_HUMAN Q5JPS2_HUMAN ----NAFGMAQANRSTTPMAPGVFLTQRRPSVGSQSN-QAGQGKRPKKGLATAKQRLGRI Q5JPR9_HUMAN Q5JPR9_HUMAN ----NAFGMAQANRSTTPMAPGVFLTQRRPSVGSQSN-QAGQGKRPKKGLATAKQRLGRI A2ABV1_MOUSE A2ABV1_MOUSE ------------------------------------------------------------ Q3UZ32_MOUSE Q3UZ32_MOUSE ------------------------------------------------------------ A2ABV3_MOUSE A2ABV3_MOUSE -------------RVDTQLVALLLMT---------------------------------- A2ABV2_MOUSE A2ABV2_MOUSE ------------------------------------------------------------ A2ABU8_MOUSE A2ABU8_MOUSE ----NAFGMAQANRSTTPMAPGVFLTQRRPSVGSQSS-QAGQGKRPKKGLATAKQRLGRI PHF8_MOUSE PHF8_MOUSE ----NAFGMAQANRSTTPMAPGVFLTQRRPSVGSQSS-QAGQGKRPKKGLATAKQRLGRI PHF2_HUMAN PHF2_HUMAN YTAAGTFTGAQAGRTSQPMAPGVFLTQRRPSASSPNNNTAAKGKRTKKGMATAKQRLGKI PHF2_MOUSE PHF2_MOUSE YTAAGTFSGSQAGRASQPMAPGVFLTQRRPSASSPNN-TAAKGKRTKKGMATAKQRLGKI Q6A023_MOUSE Q6A023_MOUSE YTAAGTFSGSQAGRASQPMAPGVFLTQRRPSASSPNN-TAAKGKRTKKGMATAKQRLGKI Q4STN5_TETNG Q4STN5_TETNG ---------------------TNNSSGGGGAKGDHTATAEAKAKRLKKGMATAKQRLGKI Q6P949_DANRE Q6P949_DANRE ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

A5PL83_DANRE A5PL83_DANRE ------------------------------------ Q5RHD1_DANRE Q5RHD1_DANRE ------------------------------------ Q08D35_XENTR Q08D35_XENTR LKLNRNGHARFFV----------------------- A4D1S9_HUMAN A4D1S9_HUMAN LKLNRNGHARFFV----------------------- JHD1D_HUMAN JHD1D_HUMAN LKLNRNGHARFFV----------------------- A6H6E5_MOUSE A6H6E5_MOUSE LKLNRNGHARFFV----------------------- JHD1D_MOUSE JHD1D_MOUSE LKLNRNGHARFFV----------------------- B9EKK1_MOUSE B9EKK1_MOUSE ------------------------------------ B6D5P9_PERLE B6D5P9_PERLE ------------------------------------ B6D5P7_PERPL B6D5P7_PERPL ------------------------------------ B6D5P8_PERMA B6D5P8_PERMA ------------------------------------ B6D5Q0_PERER B6D5Q0_PERER ------------------------------------ B6D5Q1_PERCA B6D5Q1_PERCA ------------------------------------ Q28G38_XENTR Q28G38_XENTR ------------------------------------ Q7T0U8_XENLA Q7T0U8_XENLA ------------------------------------ Q5JPS0_HUMAN Q5JPS0_HUMAN ------------------------------------ Q5JPS3_HUMAN Q5JPS3_HUMAN ------------------------------------ PHF8_HUMAN PHF8_HUMAN LKIHRNGKLLL------------------------- B7Z911_HUMAN B7Z911_HUMAN LKIHRNGKLLLRQVIVQAECRQAIHEPKLKRRDAHP Q5JPS2_HUMAN Q5JPS2_HUMAN LKIHRNGKLLLRQVIVQAECRQAIHEPKLKRRDAHP Q5JPR9_HUMAN Q5JPR9_HUMAN LKIHRNGKLLL------------------------- A2ABV1_MOUSE A2ABV1_MOUSE ------------------------------------ Q3UZ32_MOUSE Q3UZ32_MOUSE ------------------------------------ A2ABV3_MOUSE A2ABV3_MOUSE ------------------------------------ A2ABV2_MOUSE A2ABV2_MOUSE ------------------------------------ A2ABU8_MOUSE A2ABU8_MOUSE LKIHRNGKLLL------------------------- PHF8_MOUSE PHF8_MOUSE LKIHRNGKLLL------------------------- PHF2_HUMAN PHF2_HUMAN LKIHRNGKLLL------------------------- PHF2_MOUSE PHF2_MOUSE LKIHRNGKLLL------------------------- Q6A023_MOUSE Q6A023_MOUSE LKIHRNGKLLL------------------------- Q4STN5_TETNG Q4STN5_TETNG LKIHRNGKLLL------------------------- Q6P949_DANRE Q6P949_DANRE ------------------------------------ MATCH CONSENSUS ????????????????????????????????????


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