Alignment of the gene Family HBG050569 of HOVERGEN

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Isoforms are ON
Q4RP56_TETNG Q4RP56_TETNG -----------------------MNPEEQTVTWLISLGVLCSPKKNVADPEEFLKTSLKD ARHG6_CHICK ARHG6_CHICK -----------------------MNPEEQVVTWLISLGVLNSPKKIVDDPEEFLKTSLKD B7Z667_HUMAN B7Z667_HUMAN ------------------------------------------------------------ Q8N4Q3_HUMAN Q8N4Q3_HUMAN ------------------------------------------------------------ ARHG6_HUMAN ARHG6_HUMAN -----------------------MNPEEQIVTWLISLGVLESPKKTICDPEEFLKSSLKN B7Z3C7_HUMAN B7Z3C7_HUMAN ------------------------------------------------------------ B1AL37_HUMAN B1AL37_HUMAN ------------------------------------------------------------ ARHG6_RAT ARHG6_RAT -----------------------MNPEERVVTWLISLGVLESPKKTICDPEEFLKSSLKN ARHG6_MOUSE ARHG6_MOUSE -----------------------MNPEERLVTWLISLGVLESPKKTVCDPEEFLKSSLKN A2AFI0_MOUSE A2AFI0_MOUSE QSRMWLSLHSCPESCSERPRASVMNPEERLVTWLISLGVLESPKKTVCDPEEFLKSSLKN A2AFJ8_MOUSE A2AFJ8_MOUSE ------------------------------------------------------------ A5X7A1_DANRE A5X7A1_DANRE ------------------------------------------------------------ Q5PRA8_DANRE Q5PRA8_DANRE -----------------------MNSAEQTITWLITLGVLESPKKTLSDPEGFLQASLRD A5X7A2_DANRE A5X7A2_DANRE -----------------------MNSAEQTITWLITLGVLESPKKTLSDPEGFLQASLRD Q923I5_RAT Q923I5_RAT ------------------------------------------------------------ ARHG7_MOUSE ARHG7_MOUSE -----------------------MNSAEQTVTWLITLGVLESPKKTISDPEVFLQASLKD ARHG7_RAT ARHG7_RAT ------------------------------------------------------------ A3KMH4_RAT A3KMH4_RAT ------------------------------------------------------------ Q52NK0_RAT Q52NK0_RAT ------------------------------------------------------------ B7Z344_HUMAN B7Z344_HUMAN ------------------------------------------------------------ Q5W9H1_HUMAN Q5W9H1_HUMAN ------------------------IPPSKPLRGSSLWGCWSRPKKTISDPEGFLQASLKD ARHG7_HUMAN ARHG7_HUMAN -----------------------MNSAEQTVTWLITLGVLESPKKTISDPEGFLQASLKD B7Z6G2_HUMAN B7Z6G2_HUMAN ------------------------------------------------------------ B1ALK7_HUMAN B1ALK7_HUMAN ------------------------------------------------------------ B0JZX3_XENTR B0JZX3_XENTR ------------------------------------------------------------ Q6GN51_XENLA Q6GN51_XENLA -----------------------MNSAEQTVTWLITLGVLESPKKTISDPEGFLQTSLKD Q4S0P4_TETNG Q4S0P4_TETNG -----------------------MNSAEQTVTWLITLGVLESPKKTISDPEAFLQSSLKD B0S771_DANRE B0S771_DANRE -----------------------MNPAEQTVTWLITLGVLESPKKTISDPDGFLQASLKD Q501U3_DANRE Q501U3_DANRE ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

Q4RP56_TETNG Q4RP56_TETNG GVVLCKLAERLVPGFTPKYSQDPRT---------------ESDCISNIREFLRGCSSLK- ARHG6_CHICK ARHG6_CHICK GTVLCKLIHRLLPGSAEKYCLEPKN---------------EADCISNIQEFLRGCAVLK- B7Z667_HUMAN B7Z667_HUMAN ------------------------------------------------------------ Q8N4Q3_HUMAN Q8N4Q3_HUMAN ------------------------------------------------------------ ARHG6_HUMAN ARHG6_HUMAN GVVLCKLINRLMPGSVEKFCLDPQT---------------EADCINNINDFLKGCATLQ- B7Z3C7_HUMAN B7Z3C7_HUMAN ------------------------------------------------------------ B1AL37_HUMAN B1AL37_HUMAN ------------------------------------------------------------ ARHG6_RAT ARHG6_RAT GVVLCKLISRLLPGSVEKYCQEPQT---------------EADCIDNINDFLKGCATLQ- ARHG6_MOUSE ARHG6_MOUSE GVVLCKLINRLLPGSVEKYCLEPQT---------------EADCIDNINDFLKGCATLQ- A2AFI0_MOUSE A2AFI0_MOUSE GVVLCKLINRLLPGSVEKYCLEPQT---------------EADCIDNINDFLKGCATLQ- A2AFJ8_MOUSE A2AFJ8_MOUSE --MLC------------------------------------------------------- A5X7A1_DANRE A5X7A1_DANRE ------------------------------------------------------------ Q5PRA8_DANRE Q5PRA8_DANRE GVVLCKLLERLRPGSVHTIYQDPR----------------KDECLSNIREFVKGCALYH- A5X7A2_DANRE A5X7A2_DANRE GVVLCKLLERLRPGSVHTIYQDPR----------------KDECLSNIREFVKGCALYH- Q923I5_RAT Q923I5_RAT ------------------------------------------------------------ ARHG7_MOUSE ARHG7_MOUSE GVVLCRLLERLLPGTIEKVYPEPRN---------------ESECLSNIREFLRACGASLR ARHG7_RAT ARHG7_RAT ------------------------------------------------------------ A3KMH4_RAT A3KMH4_RAT ------------------------------------------------------------ Q52NK0_RAT Q52NK0_RAT ------------------------------------------------------------ B7Z344_HUMAN B7Z344_HUMAN ------------------------------------------------------------ Q5W9H1_HUMAN Q5W9H1_HUMAN GVVLCRLLERLLPGTIEKVYPEPRS---------------ESECLSNIREFLRGCGASLR ARHG7_HUMAN ARHG7_HUMAN GVVLCRLLERLLPGTIEKVYPEPRS---------------ESECLSNIREFLRGCGASLR B7Z6G2_HUMAN B7Z6G2_HUMAN ------------------------------------------------------------ B1ALK7_HUMAN B1ALK7_HUMAN ------------------------------------------------------------ B0JZX3_XENTR B0JZX3_XENTR ------------------------------------------------------------ Q6GN51_XENLA Q6GN51_XENLA GVVLCRLLERLLPGSIDKVYPEPRT---------------DTECLGNIREFLRGCSAFN- Q4S0P4_TETNG Q4S0P4_TETNG GVVLCRLLERLSPGSTEKVLPRIRHFYSGWYYSGLEKGGVSALHLRSVEDKIRPSAARAP B0S771_DANRE B0S771_DANRE GVVLCRLLERLRPGTTDKIIQDPKN---------------DSECLSNITEFLKGCAVFR- Q501U3_DANRE Q501U3_DANRE -NFSCPF---------PQIIQDPKN---------------DSECLSNITEFLKGCAVFR- MATCH CONSENSUS ????????????????????????????????????????????????????????????

Q4RP56_TETNG Q4RP56_TETNG ---V------------------EGFEPEWLYTGENFGKVLTTLLAVNFATQ--------- ARHG6_CHICK ARHG6_CHICK ---V------------------ELFEPHDLYSGEQFSKVLSTLTAVNKATE--------- B7Z667_HUMAN B7Z667_HUMAN ------------------------------------------------------------ Q8N4Q3_HUMAN Q8N4Q3_HUMAN ------------------------------------------------------------ ARHG6_HUMAN ARHG6_HUMAN ---V------------------EIFDPDDLYSGVNFSKVLSTLLAVNKATE--------- B7Z3C7_HUMAN B7Z3C7_HUMAN ------------------------------------------------------------ B1AL37_HUMAN B1AL37_HUMAN ------------------------------------------------------------ ARHG6_RAT ARHG6_RAT ---V------------------EVFEPDDLYSGANFSKVLNTLLAVNKATE--------- ARHG6_MOUSE ARHG6_MOUSE ---V------------------EVFEPDDLYSGANFSKVLNTLLAVNKATE--------- A2AFI0_MOUSE A2AFI0_MOUSE ---V------------------EVFEPDDLYSGANFSKVLNTLLAVNKATE--------- A2AFJ8_MOUSE A2AFJ8_MOUSE ------------------------------------------------------------ A5X7A1_DANRE A5X7A1_DANRE ------------------------------------------------------------ Q5PRA8_DANRE Q5PRA8_DANRE ---I------------------EVFEANDLLQGQNFSKVLNCLVALNKATS--------- A5X7A2_DANRE A5X7A2_DANRE ---I------------------EVFEANDLLQGQNFSKVLNCLVALNKATS--------- Q923I5_RAT Q923I5_RAT ------------------------------------------------------------ ARHG7_MOUSE ARHG7_MOUSE ---L------------------ETFDANDLYQGQNFNKVLSSLVTLNKVTA--------- ARHG7_RAT ARHG7_RAT ------------------------------------------------------------ A3KMH4_RAT A3KMH4_RAT ------------------------------------------------------------ Q52NK0_RAT Q52NK0_RAT ------------------------------------------------------------ B7Z344_HUMAN B7Z344_HUMAN ------------------------------------------------------------ Q5W9H1_HUMAN Q5W9H1_HUMAN ---L------------------ETFDANDLYQGQNFNKVLSSLVTLNKVTA--------- ARHG7_HUMAN ARHG7_HUMAN LELLFPPSQPPQHLVTTILLSASTFDANDLYQGQNFNKVLSSLVTLNKVTA--------- B7Z6G2_HUMAN B7Z6G2_HUMAN ---M------------------KTFDANDLYQGQNFNKVLSSLVTLNKVTA--------- B1ALK7_HUMAN B1ALK7_HUMAN ------------------------------------------------------------ B0JZX3_XENTR B0JZX3_XENTR ------------------------------------------------------------ Q6GN51_XENLA Q6GN51_XENLA ---L------------------ETFDANDLYQGQNFNKVLNSLVLLNKVTA--------- Q4S0P4_TETNG Q4S0P4_TETNG LALT------------------QPFEAGDLLLGLNFSKVLSSLVALNKVTAGQSTWKHWK B0S771_DANRE B0S771_DANRE ---V-------------------PFEAGDLLQGHNISRVLTTLVALNKVTA--------- Q501U3_DANRE Q501U3_DANRE ---V------------------EPFEAGDLLQGHNISRVLTTLVALNKVTA--------- MATCH CONSENSUS ????????????????????????????????????????????????????????????

Q4RP56_TETNG Q4RP56_TETNG ------------------------------------DCAPERSCSQSGASSPSQSTASHS ARHG6_CHICK ARHG6_CHICK ------------------------------------DQPSEGPCSHPSALSSAAGGAHTD B7Z667_HUMAN B7Z667_HUMAN ------------------------------------------------------------ Q8N4Q3_HUMAN Q8N4Q3_HUMAN ------------------------------------------------------------ ARHG6_HUMAN ARHG6_HUMAN ------------------------------------DQLSERPCGRSSSLSAANTSQTNP B7Z3C7_HUMAN B7Z3C7_HUMAN ------------------------------------------------------------ B1AL37_HUMAN B1AL37_HUMAN ------------------------------------------------------------ ARHG6_RAT ARHG6_RAT ------------------------------------DQLSERPCGRSSSLSATTSSQTNP ARHG6_MOUSE ARHG6_MOUSE ------------------------------------DQLSERPCGRSSSLSAATSSQTNP A2AFI0_MOUSE A2AFI0_MOUSE ------------------------------------DQLSERPCGRSSSLSAATSSQTNP A2AFJ8_MOUSE A2AFJ8_MOUSE ------------------------------------------------------------ A5X7A1_DANRE A5X7A1_DANRE ------------------------------------------------------------ Q5PRA8_DANRE Q5PRA8_DANRE ----------------------------------ESGGGSNSVCSRQSSSLRIKSFDSLN A5X7A2_DANRE A5X7A2_DANRE ----------------------------------ESGGGSNSVCSRQSSSLRIKSFDSLN Q923I5_RAT Q923I5_RAT ------------------------------------------------------------ ARHG7_MOUSE ARHG7_MOUSE ----------------------------------DIGLGSDSVCARPSS-HRIKSFDSLG ARHG7_RAT ARHG7_RAT ------------------------------------------------------------ A3KMH4_RAT A3KMH4_RAT ------------------------------------------------------------ Q52NK0_RAT Q52NK0_RAT ------------------------------------------------------------ B7Z344_HUMAN B7Z344_HUMAN ------------------------------------------------------------ Q5W9H1_HUMAN Q5W9H1_HUMAN ----------------------------------DIGLGSDSVCARPSS-HRIKSFDSLG ARHG7_HUMAN ARHG7_HUMAN ----------------------------------DIGLGSDSVCARPSS-HRIKSFDSLG B7Z6G2_HUMAN B7Z6G2_HUMAN ----------------------------------DIGLGSDSVCARPSS-HRIKSFDSLG B1ALK7_HUMAN B1ALK7_HUMAN ------------------------------------------------------------ B0JZX3_XENTR B0JZX3_XENTR ------------------------------------------------------------ Q6GN51_XENLA Q6GN51_XENLA ----------------------------------DIGLGSDSVCSRSSS-HRIKSFDSLG Q4S0P4_TETNG Q4S0P4_TETNG CDLDGNCGYFSSTSAWVWSADAGSGVFMFGSFCSDISVGSDTVSARHSSSHRIKSFESLS B0S771_DANRE B0S771_DANRE ----------------------------------DIGIGSDSVCTRHSSAHRIKSFESLA Q501U3_DANRE Q501U3_DANRE ----------------------------------DIGIGSDSVCMRHSSAHRIKSFESLA MATCH CONSENSUS ????????????????????????????????????????????????????????????

Q4RP56_TETNG Q4RP56_TETNG LSSTKSKGSLRRQSKSV-------EMSENGGGGQQMVKARFNFKQNNEDELSFSKGDVIV ARHG6_CHICK ARHG6_CHICK SNSTASQSAK--------------EMTEN-GSHQLVVKARFNFKQTNEDELSVNKGDIIY B7Z667_HUMAN B7Z667_HUMAN -------------------------MTEN-GSHQLIVKARFNFKQTNEDELSVCKGDIIY Q8N4Q3_HUMAN Q8N4Q3_HUMAN ------------------------------------------------------------ ARHG6_HUMAN ARHG6_HUMAN QGAVSSTVSGLQRQSKTV------EMTEN-GSHQLIVKARFNFKQTNEDELSVCKGDIIY B7Z3C7_HUMAN B7Z3C7_HUMAN -------------------------MTEN-GSHQLIVKARFNFKQTNEDELSVCKGDIIY B1AL37_HUMAN B1AL37_HUMAN -------------------------MTEN-GSHQLIVKARFNFKQTNEDELSVCKGDIIY ARHG6_RAT ARHG6_RAT QAAVPSTTPEQQSEEKAA------EMTEN-GSHQLIVKARFNFKQTNEDELSVCKGDIIY ARHG6_MOUSE ARHG6_MOUSE QVAVPSTAPEQHSEEKA-------EMTEN-GSHQLIVKARFNFKQTNEDELSVCKGDIIY A2AFI0_MOUSE A2AFI0_MOUSE QVAVPSTAPEQHSEEKA-------EMTEN-GSHQLIVKARFNFKQTNEDELSVCKGDIIY A2AFJ8_MOUSE A2AFJ8_MOUSE ------------------------------------------------------------ A5X7A1_DANRE A5X7A1_DANRE -------------------------MSEN-SAPQVLVKARFNFQQTNEDELSFSKGDIIQ Q5PRA8_DANRE Q5PRA8_DANRE CSSTHRRSSRHKFNQYRSL-----DMSEN-SAPQVLVKARFNFQQTNEDELSFSKGDIIQ A5X7A2_DANRE A5X7A2_DANRE CSSTHRRSSRHKFNQYRSL-----DMSEN-SAPQVLVKARFNFQQTNEDELSFSKGDIIQ Q923I5_RAT Q923I5_RAT -------------------------MTDN-ANSQLVVRAKFNFQQTNEDELSFSKGDVIH ARHG7_MOUSE ARHG7_MOUSE SQSSHSRTSKLLQSQYRSL-----DMTDN-TNSQLVVRAKFNFQQTNEDELSFSKGDVIH ARHG7_RAT ARHG7_RAT -------------------------MTDN-ANSQLVVRAKFNFQQTNEDELSFSKGDVIH A3KMH4_RAT A3KMH4_RAT ---SHSRTSKLLQSQYRSL-----DMTDN-ANSQLVVRAKFNFQQTNEDELSFSKGDVIH Q52NK0_RAT Q52NK0_RAT -------------------------MTDN-ANSQLVVRAKFNFQQTNEDELSFSKGDVIH B7Z344_HUMAN B7Z344_HUMAN ------------------------------------------------------------ Q5W9H1_HUMAN Q5W9H1_HUMAN SQSLHTRTSKLFQGQYRSL-----DMTDN-SNNQLVVRAKFNFQQTNEDELSFSKGDVIH ARHG7_HUMAN ARHG7_HUMAN SQSLHTRTSKLFQGQYRSL-----DMTDN-SNNQLVVRAKFNFQQTNEDELSFSKGDVIH B7Z6G2_HUMAN B7Z6G2_HUMAN SQSLHTRTSKLFQGQYRSL-----DMTDN-SNNQLVVRAKFNFQQTNEDELSFSKGDVIH B1ALK7_HUMAN B1ALK7_HUMAN -------------------------MTDN-SNNQLVVRAKFNFQQTNEDELSFSKGDVIH B0JZX3_XENTR B0JZX3_XENTR -------------------------MTEN-SNHHMVVRAKFNFQQTNEDELSFNKGDLIH Q6GN51_XENLA Q6GN51_XENLA SQSVLSRSSKLLQSQYRSL-----DMTEN-SNHHMVVRAKFNFQQTNEDELSFNKGDIIH Q4S0P4_TETNG Q4S0P4_TETNG CQSSLGRSSKLLQNQFRSL-----DMSEN-SGQQLLVKARFNFQQTNEDELTFTKGDLIS B0S771_DANRE B0S771_DANRE SQSSLGRSSKLLHNQFRSL-----DMTDN-SNAQLVVKARFNFQQTNEDELTFSKGDLIS Q501U3_DANRE Q501U3_DANRE SQSSLGRSSKLLHNQFRSLVSNIGDMTDN-SNAQLVVKARFNFQQTNEDELTFSKGDLIS MATCH CONSENSUS ?????????????????????????M??N????Q??V?A?FNF?QTNEDEL???KGD?I?

Q4RP56_TETNG Q4RP56_TETNG VTRQEEGGWWEGTLNGRTGWFPSNYVREIKQCE--------------------------- ARHG6_CHICK ARHG6_CHICK VTRVEEGGWWEGTLNGKTGWFPSNYVREIKSTD--------------------------- B7Z667_HUMAN B7Z667_HUMAN VTRVEEGGWWEGTLNGRTGWFPSNYVREIKSSE--------------------------- Q8N4Q3_HUMAN Q8N4Q3_HUMAN ------------------------------------------------------------ ARHG6_HUMAN ARHG6_HUMAN VTRVEEGGWWEGTLNGRTGWFPSNYVREIKSSE--------------------------- B7Z3C7_HUMAN B7Z3C7_HUMAN VTRVEEGGWWEGTLNGRTGWFPSNYVREIKSSDGVSLLLPGLECNGAISAHHNLCLPGSK B1AL37_HUMAN B1AL37_HUMAN VTRVEEGGWWEGTLNGRTGWFPSNYVREIKSSE--------------------------- ARHG6_RAT ARHG6_RAT VTRVEEGGWWEGTLNGRTGWFPSNYVREIKPSE--------------------------- ARHG6_MOUSE ARHG6_MOUSE VTRVEEGGWWEGTLNGRTGWFPSNYVREIKPSE--------------------------- A2AFI0_MOUSE A2AFI0_MOUSE VTRVEEGGWWEGTLNGRTGWFPSNYVREIKPSE--------------------------- A2AFJ8_MOUSE A2AFJ8_MOUSE ------------------------------------------------------------ A5X7A1_DANRE A5X7A1_DANRE VTRQEEGGWWEGALNGKTGWFPSNYVKEIKGSD--------------------------- Q5PRA8_DANRE Q5PRA8_DANRE VTRQEEGGWWEGALNGKTGWFPSNYVKETKGSD--------------------------- A5X7A2_DANRE A5X7A2_DANRE VTRQEEGGWWEGALNGKTGWFPSNYVKEIKGSD--------------------------- Q923I5_RAT Q923I5_RAT VTRVEEGGWWEGTHNGRTGWFPSNYVREIKPSE--------------------------- ARHG7_MOUSE ARHG7_MOUSE VTRVEEGGWWEGTHNGRTGWFPSNYVREIKPSE--------------------------- ARHG7_RAT ARHG7_RAT VTRVEEGGWWEGTHNGRTGWFPSNYVREIKPSE--------------------------- A3KMH4_RAT A3KMH4_RAT VTRVEEGGWWEGTHNGRTGWFPSNYVREIKPSE--------------------------- Q52NK0_RAT Q52NK0_RAT VTRVEEGGWWEGTHNGRTGWFPSNYVREIKPSE--------------------------- B7Z344_HUMAN B7Z344_HUMAN -----------------MGSCSSQSVQKTRRGR--------------------------- Q5W9H1_HUMAN Q5W9H1_HUMAN VTRVEEGGWWEGTLNGRTGWFPSNYVREVKASE--------------------------- ARHG7_HUMAN ARHG7_HUMAN VTRVEEGGWWEGTLNGRTGWFPSNYVREVKASE--------------------------- B7Z6G2_HUMAN B7Z6G2_HUMAN VTRVEEGGWWEGTLNGRTGWFPSNYVREVKASE--------------------------- B1ALK7_HUMAN B1ALK7_HUMAN VTRVEEGGWWEGTLNGRTGWFPSNYVREVKASE--------------------------- B0JZX3_XENTR B0JZX3_XENTR VTRLEEGGWWEGTHSGKTGWFPSNYVREVKSSE--------------------------- Q6GN51_XENLA Q6GN51_XENLA VTRQEDGGWWEGTHSGKTGWFPSNYVREVKSSE--------------------------- Q4S0P4_TETNG Q4S0P4_TETNG VSRQEEGGWWEGTLNGRTGWFPSNYVREVRGSD--------------------------- B0S771_DANRE B0S771_DANRE VTRTEEGGWWEGILNGKTGWFPSNYVKEVKGSD--------------------------- Q501U3_DANRE Q501U3_DANRE VTRTEEGGWWEGILNGKTGWFPSNYVKEVKGSD--------------------------- MATCH CONSENSUS VTR?EEGGWWEG??NG?TGWFPSNYV?E?K?S????????????????????????????

Q4RP56_TETNG Q4RP56_TETNG KPVSPKA------------TQLTKNYYSV---DILEYEREFVRELQSVLTCYLRPLQASD ARHG6_CHICK ARHG6_CHICK KPLSPKA------LKGLESTQLTKNYYPVVLQNILETERDYAKELQSLLGTYLRPLQSYD B7Z667_HUMAN B7Z667_HUMAN RPLSPKA------VKGFETAPLTKNYYTVVLQNILDTEKEYAKELQSLLVTYLRPLQSNN Q8N4Q3_HUMAN Q8N4Q3_HUMAN --------------------------------------------------------HASD ARHG6_HUMAN ARHG6_HUMAN RPLSPKA------VKGFETAPLTKNYYTVVLQNILDTEKEYAKELQSLLVTYLRPLQSNN B7Z3C7_HUMAN B7Z3C7_HUMAN RPLSPKA------VKGFETAPLTKNYYTVVLQNILDTEKEYAKELQSLLVTYLRPLQSNN B1AL37_HUMAN B1AL37_HUMAN RPLSPKA------VKGFETAPLTKNYYTVVLQNILDTEKEYAKELQSLLVTYLRPLQSNN ARHG6_RAT ARHG6_RAT RPLSPKA------VKGFDTAPLTKNYYTVVLQNILDTEKEYAKELQSLLVTYLRPLQSNN ARHG6_MOUSE ARHG6_MOUSE RPLSPKA------IKGFDTAPLTKNYYTVVLQNILDTEKEYAKELQSLLVTYLRPLQSNN A2AFI0_MOUSE A2AFI0_MOUSE RPLSPKA------IKGFDTAPLTKNYYTVVLQNILDTEKEYAKELQSLLVTYLRPLQSNN A2AFJ8_MOUSE A2AFJ8_MOUSE ----------------------------LVLQNILDTEKEYAKELQSLLVTYLRPLQSNN A5X7A1_DANRE A5X7A1_DANRE KPVSPKTGTLKSPPKAIESANFCKTYYNVVVQNILQTETEYCKELQNLLSVYLRALQPTD Q5PRA8_DANRE Q5PRA8_DANRE KPVSPKTGTLKSPPKAIESANFCKTYYNVVVQNILQTETEYCKELQNLLSVYLRALQPTD A5X7A2_DANRE A5X7A2_DANRE KPVSPKTGTLKSPPKAIESANFCKTYYNVVVQNILQTETEYCKELQNLLSVYLRALQPTD Q923I5_RAT Q923I5_RAT KPVSPKSGTLKSPPKGFDTTAINKSYYNVVLQNILETEHEYSKELQSVLSTYLWPLQTSE ARHG7_MOUSE ARHG7_MOUSE KPVSPKSGTLKSPPKGFDTTAINKSYYNVVLQNILETEHEYSKELQSVLSTYLRPLQTSD ARHG7_RAT ARHG7_RAT KPVSPKSGTLKSPPKGFDTTAINKSYYNVVLQNILETEHEYSKELQSVLSTYLWPLQTSE A3KMH4_RAT A3KMH4_RAT KPVSPKSGTLKSPPKGFDTTAINKSYYNVVLQNILETEHEYSKELQSVLSTYLWPLQTSE Q52NK0_RAT Q52NK0_RAT KPVSPKSGTLKSPPKGFDTTAINKSYYNVVLQNILETEHEYSKELQSVLSTYLWPLQTSE B7Z344_HUMAN B7Z344_HUMAN ---------------------------KVVLQNILETENEYSKELQTVLSTYLRPLQTSE Q5W9H1_HUMAN Q5W9H1_HUMAN KPVSPKSGTLKSPPKGFDTTAINKSYYNVVLQNILETENEYSKELQTVLSTYLRPLQTSE ARHG7_HUMAN ARHG7_HUMAN KPVSPKSGTLKSPPKGFDTTAINKSYYNVVLQNILETENEYSKELQTVLSTYLRPLQTSE B7Z6G2_HUMAN B7Z6G2_HUMAN KPVSPKSGTLKSPPKGFDTTAINKSYYNVVLQNILETENEYSKELQTVLSTYLRPLQTSE B1ALK7_HUMAN B1ALK7_HUMAN KPVSPKSGTLKSPPKGFDTTAINKSYYNVVLQNILETENEYSKELQTVLSTYLRPLQTSE B0JZX3_XENTR B0JZX3_XENTR KPVSPKSTTLKSPPKGFDTSAINKSYYNVVLQNILDTEGEYSKELQDILSNYLRHLQTSE Q6GN51_XENLA Q6GN51_XENLA KPVSPKSTTLKSPPKGFDTSAINKSYYNVVLQNILETESEYSKELQDMLSNYLRHLQTSE Q4S0P4_TETNG Q4S0P4_TETNG KQVSPKSGALKSPPKGFDTSAISKTYYNLVLQNILETETEYSKDLQSLLTIYLRPLQNTD B0S771_DANRE B0S771_DANRE KQVSPKSGNLKSPPKGFDTASISKTYYNLVLQNILETETEYSRELQNLLTSYLRPLQMTE Q501U3_DANRE Q501U3_DANRE KQVSPKSGNLKSPPKGFDTASISKTYYNLVLQNILETETEYSRELQNLLTSYLRPLQMTE MATCH : : CONSENSUS ???SPK????????K????????K?YY?VVLQNIL?TE?EY?KELQ??L??YLR?LQ???

Q4RP56_TETNG Q4RP56_TETNG -------------------------------------------------KLSASDCTTLC ARHG6_CHICK ARHG6_CHICK -------------------------------------------------KLSAVDIASLL B7Z667_HUMAN B7Z667_HUMAN -------------------------------------------------NLSTVEVTSLL Q8N4Q3_HUMAN Q8N4Q3_HUMAN ------------------------------------------------------------ ARHG6_HUMAN ARHG6_HUMAN -------------------------------------------------NLSTVEVTSLL B7Z3C7_HUMAN B7Z3C7_HUMAN -------------------------------------------------NLSTVEVTSLL B1AL37_HUMAN B1AL37_HUMAN -------------------------------------------------NLSTVEVTSLL ARHG6_RAT ARHG6_RAT -------------------------------------------------NLSTVEFTCLL ARHG6_MOUSE ARHG6_MOUSE -------------------------------------------------NLSTVEFTCLL A2AFI0_MOUSE A2AFI0_MOUSE -------------------------------------------------NLSTVEFTCLL A2AFJ8_MOUSE A2AFJ8_MOUSE -------------------------------------------------NLSTVEFTCLL A5X7A1_DANRE A5X7A1_DANRE -------------------------------------------------RLSVSDISHIM Q5PRA8_DANRE Q5PRA8_DANRE -------------------------------------------------RLSVSDISHIM A5X7A2_DANRE A5X7A2_DANRE -------------------------------------------------RLSVSDISHIM Q923I5_RAT Q923I5_RAT -------------------------------------------------KLSSANTSYLM ARHG7_MOUSE ARHG7_MOUSE -------------------------------------------------KLSSANTSYLM ARHG7_RAT ARHG7_RAT -------------------------------------------------KLSSANTSYLM A3KMH4_RAT A3KMH4_RAT -------------------------------------------------KLSSANTSYLM Q52NK0_RAT Q52NK0_RAT -------------------------------------------------KLSSANTSYLM B7Z344_HUMAN B7Z344_HUMAN -------------------------------------------------KLSSANISYLM Q5W9H1_HUMAN Q5W9H1_HUMAN -------------------------------------------------KLSSANISYLM ARHG7_HUMAN ARHG7_HUMAN -------------------------------------------------KLSSANISYLM B7Z6G2_HUMAN B7Z6G2_HUMAN -------------------------------------------------KLSSANISYLM B1ALK7_HUMAN B1ALK7_HUMAN -------------------------------------------------KLSSANISYLM B0JZX3_XENTR B0JZX3_XENTR -------------------------------------------------KLSPTNISYLL Q6GN51_XENLA Q6GN51_XENLA -------------------------------------------------KLSPTNISYLM Q4S0P4_TETNG Q4S0P4_TETNG KYVSLTPKRLSNRNQRRTRSKNTFCFNLLCFLNFTRYFSSVLTDAGFFNRLSALDVALIL B0S771_DANRE B0S771_DANRE -------------------------------------------------RLSPADVSVIL Q501U3_DANRE Q501U3_DANRE -------------------------------------------------RLSPADVSVIL MATCH CONSENSUS ??????????????????????????????????????????????????LS????????

Q4RP56_TETNG Q4RP56_TETNG GKLEEILTFQQGLCVALEECTKAPEGQQRVAGCYLNLMSQIRTLYLAYCSSHPSAVSILT ARHG6_CHICK ARHG6_CHICK GNVEEISAFQQTLNQALEDVAKLPENQQRVGGCFMNLMAQFRSLYLTYCANHPSAVSVLT B7Z667_HUMAN B7Z667_HUMAN GNFEEVCTFQQTLCQALEECSKFPENQHKVGGCLLSLMPHFKSMYLAYCANHPSAVNVLT Q8N4Q3_HUMAN Q8N4Q3_HUMAN ------------------------------------------------------------ ARHG6_HUMAN ARHG6_HUMAN GNFEEVCTFQQTLCQALEECSKFPENQHKVGGCLLSLMPHFKSMYLAYCANHPSAVNVLT B7Z3C7_HUMAN B7Z3C7_HUMAN GNFEEVCTFQQTLCQALEECSKFPENQHKVGGCLLSLMPHFKSMYLAYCANHPSAVNVLT B1AL37_HUMAN B1AL37_HUMAN GNFEEVCTFQQTLCQALEECSKFPENQHKVGGCLLSLMPHFKSMYLAYCANHPSAVNVLT ARHG6_RAT ARHG6_RAT GNFEEVCTFQQTLCQALEECSKSPENQHKVGGCLLNLMPHFKSMYLAYCANHPSAVNVLT ARHG6_MOUSE ARHG6_MOUSE GNFEEVCTFQQTLCQALEECSKFPENQHKVGGCLLNLMPHFKSMYLAYCANHPSAVNVLT A2AFI0_MOUSE A2AFI0_MOUSE GNFEEVCTFQQTLCQALEECSKFPENQHKVGGCLLNLMPHFKSMYLAYCANHPSAVNVLT A2AFJ8_MOUSE A2AFJ8_MOUSE GNFEEVCTFQQTLCQALEECSKFPENQHKVGGCLLNLMPHFKSMYLAYCANHPSAVNVLT A5X7A1_DANRE A5X7A1_DANRE GNLEEISSFQQTLVHSLEENVKVSDSQQRIGGFFLSLLTQMRSLYVTYCSNHPSAVNVLT Q5PRA8_DANRE Q5PRA8_DANRE GNLEEISSFQQTLVHSLEENVKVSDSQQRIGGFFLSLLTQMRSLYVTYCSNHPSAVNVLT A5X7A2_DANRE A5X7A2_DANRE GNLEEISSFQQTLVHSLEENVKVSDSQQRIGGFFLSLLTQMRSLYVTYCSNHPSAVNVLT Q923I5_RAT Q923I5_RAT GNLEEISSFQQVLVQSLEECTKSPEAQQRVGGCFLSLMPQMRTLYLAYCANHPSAVSVLT ARHG7_MOUSE ARHG7_MOUSE GNLEEISSFQQVLVQSLEECTKSPEAQQRVGGCFLSLMPQMRTLYLAYCANHPSAVSVLT ARHG7_RAT ARHG7_RAT GNLEEISSFQQVLVQSLEECTKSPEAQQRVGGCFLSLMPQMRTLYLAYCANHPSAVSVLT A3KMH4_RAT A3KMH4_RAT GNLEEISSFQQVLVQSLEECTKSPEAQQRVGGCFLSLMPQMRTLYLAYCANHPSAVSVLT Q52NK0_RAT Q52NK0_RAT GNLEEISSFQQVLVQSLEECTKSPEAQQRVGGCFLSLMPQMRTLYLAYCANHPSAVSVLT B7Z344_HUMAN B7Z344_HUMAN GNLEEICSFQQMLVQSLEECTKLPEAQQRVGGCFLNLMPQMKTLYLTYCANHPSAVNVLT Q5W9H1_HUMAN Q5W9H1_HUMAN GNLEEICSFQQMLVQSLEECTKLPEAQQRVGGCFLNLMPQMKTLYLTYCANHPSAVNVLT ARHG7_HUMAN ARHG7_HUMAN GNLEEICSFQQMLVQSLEECTKLPEAQQRVGGCFLNLMPQMKTLYLTYCANHPSAVNVLT B7Z6G2_HUMAN B7Z6G2_HUMAN GNLEEICSFQQMLVQSLEECTKLPEAQQRVGGCFLNLMPQMKTLYLTYCANHPSAVNVLT B1ALK7_HUMAN B1ALK7_HUMAN GNLEEICSFQQMLVQSLEECTKLPEAQQRVGGCFLNLMPQMKTLYLTYCANHPSAVNVLT B0JZX3_XENTR B0JZX3_XENTR GNLEEICAFQQILVQSLEECTKLPEGQQRVGGCFMSLMPQMKSLYIAYCANHPSAVNVLT Q6GN51_XENLA Q6GN51_XENLA GNLEEICAFQQMLVQSLEECTKLPEGQQRVGGCFVNLMPQIKSLYLAYCANHPSAVNVLT Q4S0P4_TETNG Q4S0P4_TETNG GNLEEICTFQQMLVQSLEECTKLPETQQRVGGFFLNLMPQMRALYSSYCSNHPSAVNVLT B0S771_DANRE B0S771_DANRE GNLEEISTFQQTLVQSLEDLTKLPELQQKVGGFFLNLMPQMRSLNVSYCSNHPSTVNVLT Q501U3_DANRE Q501U3_DANRE GNLEEISTFQQTLVQSLEDLTKLPELQQKVGGFFLNLMPQMRSLNVSYCSNHPSTVNVLT MATCH CONSENSUS GN?EE???FQQ?L?Q?LEE??K?PE?Q??VGG??L?LM??????Y??YC?NHPSAV?VLT

Q4RP56_TETNG Q4RP56_TETNG NHSEELDKFMESQGAR---ILTLTTSLSKPFMRLDKYPTLLQELERHVEEAHPDYSDILK ARHG6_CHICK ARHG6_CHICK QHSDELEKFMESQGAANPGILILTTSLSKPFLRLDKYVTLLQELERHMEEAHADHEDVLK B7Z667_HUMAN B7Z667_HUMAN QHSDELEQFMENQGASSPGILILTTNLSKPFMRLEKYVTLLQELERHMEDTHPDHQDILK Q8N4Q3_HUMAN Q8N4Q3_HUMAN ------------------------------------------------------------ ARHG6_HUMAN ARHG6_HUMAN QHSDELEQFMENQGASSPGILILTTNLSKPFMRLEKYVTLLQELERHMEDTHPDHQDILK B7Z3C7_HUMAN B7Z3C7_HUMAN QHSDELEQFMENQGASSPGILILTTNLSKPFMRLEKYVTLLQELERHMEDTHPDHQDILK B1AL37_HUMAN B1AL37_HUMAN QHSDELEQFMENQGASSPGILILTTNLSKPFMRLEKYVTLLQELERHMEDTHPDHQDILK ARHG6_RAT ARHG6_RAT QHSDDLERFMENQGASSPGILILTTSLSKPFMRLEKYVTLLQELERHMEDTHPDHQDILK ARHG6_MOUSE ARHG6_MOUSE QHSDDLERFMENQGASSPGILILTTSLSKPFMRLEKYVTLLQELERHMEDTHPDHQDILK A2AFI0_MOUSE A2AFI0_MOUSE QHSDDLERFMENQGASSPGILILTTSLSKPFMRLEKYVTLLQELERHMEDTHPDHQDILK A2AFJ8_MOUSE A2AFJ8_MOUSE QHSDDLERFMENQGASSPGILILTTSLSKPFMRLEKYVTLLQELERHMEDTHPDHQDILK A5X7A1_DANRE A5X7A1_DANRE QHSEELGEFMESKGANTPGILTLTTGLSKPFLRLEKYPTLLKEMERHMEPLHPDYPDIQK Q5PRA8_DANRE Q5PRA8_DANRE QHSEELGEFMESKGANTPGILTLTTGLSKPFLRLEKYPTLLKEMERHMEPLHPDYPDIQK A5X7A2_DANRE A5X7A2_DANRE QHSEELGEFMESKGANTPGILTLTTGLSKPFLRLEKYPTLLKEMERHMEPLHPDYPDIQK Q923I5_RAT Q923I5_RAT EHSEDLGEFMETKGASSPGILVLTTGLSKPFMRLDKYPTLLKELERHMEDYHPDRQDIQK ARHG7_MOUSE ARHG7_MOUSE EHSEDLGEFMETKGASSPGILVLTTGLSKPFMRLDKYPTLLKELERHMEDYHPDRQDIQK ARHG7_RAT ARHG7_RAT EHSEDLGEFMETKGASSPGILVLTTGLSKPFMRLDKYPTLLKELERHMEDYHPDRQDIQK A3KMH4_RAT A3KMH4_RAT EHSEDLGEFMETKGASSPGILVLTTGLSKPFMRLDKYPTLLKELERHMEDYHPDRQDIQK Q52NK0_RAT Q52NK0_RAT EHSEDLGEFMETKGASSPGILVLTTGLSKPFMRLDKYPTLLKELERHMEDYHPDRQDIQK B7Z344_HUMAN B7Z344_HUMAN EHSEELGEFMETKGASSPGILVLTTGLSKPFMRLDKYPTLLKELERHMEDYHTDRQDIQK Q5W9H1_HUMAN Q5W9H1_HUMAN EHSEELGEFMETKGASSPGILVLTTGLSKPFMRLDKYPTLLKELERHMEDYHTDRQDIQK ARHG7_HUMAN ARHG7_HUMAN EHSEELGEFMETKGASSPGILVLTTGLSKPFMRLDKYPTLLKELERHMEDYHTDRQDIQK B7Z6G2_HUMAN B7Z6G2_HUMAN EHSEELGEFMETKGASSPGILVLTTGLSKPFMRLDKYPTLLKELERHMEDYHTDRQDIQK B1ALK7_HUMAN B1ALK7_HUMAN EHSEELGEFMETKGASSPGILVLTTGLSKPFMRLDKYPTLLKELERHMEDYHTDRQDIQK B0JZX3_XENTR B0JZX3_XENTR QHSEELGEFMEMKGANSPGILVLTTGLSKPFMRLDKYPTLLKELERHMEDYHPDRPDIQK Q6GN51_XENLA Q6GN51_XENLA QHSEELGEFMEMKGANSPGILVLTTGLSKPFMRLDKYPTLLKELERHMEDYHPDRPDIQK Q4S0P4_TETNG Q4S0P4_TETNG QQSEVLGDFMEGRGAVSPGILTLTTGLSKPFMRLDKYPTLLKELERHMEEAHPDRPEIQK B0S771_DANRE B0S771_DANRE VHSEELGEFMEARGASVPGILTLTSGLSKPFMRLDRYPTLLKELERHMEEGHPDRTEIQK Q501U3_DANRE Q501U3_DANRE VHSEELGEFMEARGASVPGILTLTSGLSKPFMRLDRYPTLLKELERHMEEGHPDRTEIQK MATCH CONSENSUS ?HS??L??FME??GA??PGIL?LTT?LSKPFMRL?KY?TLL?ELERHME??H?D??DI?K

Q4RP56_TETNG Q4RP56_TETNG ATAAFKNLVAQCQDLRKRKNLELQILSEPVRAWEGDTIKSLGSVLYMSQVHIKNGSAEEK ARHG6_CHICK ARHG6_CHICK AITSFKSLVSQCQELRKRKQLELQILSESIQRWEGEDIKTMGNIIYMSQVMVQSGGSEEK B7Z667_HUMAN B7Z667_HUMAN AIVAFKTLMGQCQDLRKRKQLELQILSEPIQAWEGEDIKN-------------------- Q8N4Q3_HUMAN Q8N4Q3_HUMAN ------------------------------------------------------GACEEK ARHG6_HUMAN ARHG6_HUMAN AIVAFKTLMGQCQDLRKRKQLELQILSEPIQAWEGEDIKNLGNVIFMSQVMVQYGACEEK B7Z3C7_HUMAN B7Z3C7_HUMAN AIVAFKTLMGQCQDLRKRKQLELQILSEPIQAWEGEDIKNLGNVIFMSQVMVQYGACEEK B1AL37_HUMAN B1AL37_HUMAN AIVAFKTLMGQCQDLRKRKQLELQILSEPIQAWEGEDIKNLGNVIFMSQVMVQYGACEEK ARHG6_RAT ARHG6_RAT AIIAFKSLMGQCQDLRKRKQLELQILSEPIQAWEGDDIKTLGNVIFMSQVVMQHGACEEK ARHG6_MOUSE ARHG6_MOUSE AIIAFKTLMGQCQDLRKRKQLELQILSEPIQAWEGDDIKTLGNVIFMSQVVMQHGACEEK A2AFI0_MOUSE A2AFI0_MOUSE AIIAFKTLMGQCQDLRKRKQLELQILSEPIQAWEGDDIKTLGNVIFMSQVVMQHGACEEK A2AFJ8_MOUSE A2AFJ8_MOUSE AIIAFKTLMGQCQDLRKRKQLELQILSEPIQAWEGDDIKTLGNVIFMSQVVMQHGACEEK A5X7A1_DANRE A5X7A1_DANRE SMTLFKNLSAQCQEVRKRKELELQILMESIRGWEGEGIKTLGTVLFMSQVIIQNHGAEEK Q5PRA8_DANRE Q5PRA8_DANRE SMTLFKNLSAQCQEVRKRKELELQILMESIRGWEGEGIKTLGTVLFMSQVIIQNHGAEEK A5X7A2_DANRE A5X7A2_DANRE SMTLFKNLSAQCQEVRKRKELELQILMESIRGWEGEGIKTLGTVLFMSQVIIQNHGAEEK Q923I5_RAT Q923I5_RAT SMTAFKNLSAQCQEVRKRKELELQILTEPIRSWEGDDIKTLGSVTYMSQVTIQCAGSEEK ARHG7_MOUSE ARHG7_MOUSE SMTAFKNLSAQCQEVRKRKELELQILTEPIRSWEGDDIKTLGSVTYMSQVTIQCAGSEEK ARHG7_RAT ARHG7_RAT SMTAFKNLSAQCQEVRKRKELELQILTEPIRSWEGDDIKTLGSVTYMSQVTIQCAGSEEK A3KMH4_RAT A3KMH4_RAT SMTAFKNLSAQCQEVRKRKELELQILTEPIRSWEGDDIKTLGSVTYMSQVTIQCAGSEEK Q52NK0_RAT Q52NK0_RAT SMTAFKNLSAQCQEVRKRKELELQILTEPIRSWEGDDIKTLGSVTYMSQVTIQCAGSEEK B7Z344_HUMAN B7Z344_HUMAN SIAAFKNLSAQCQEVRKRKELELQILTEAIRNWEGDDIKTLGNVTYMSQVLIQCAGSEEK Q5W9H1_HUMAN Q5W9H1_HUMAN SMAAFKNLSAQCQEVRKRKELELQILTEAIRNWEGDDIKTLGNVTYMSQVLIQCAGSEEK ARHG7_HUMAN ARHG7_HUMAN SMAAFKNLSAQCQEVRKRKELELQILTEAIRNWEGDDIKTLGNVTYMSQVLIQCAGSEEK B7Z6G2_HUMAN B7Z6G2_HUMAN SMAAFKNLSAQCQEVRKRKELELQILTEAIRNWEGDDIKTLGNVTYMSQVLIQCAGSEEK B1ALK7_HUMAN B1ALK7_HUMAN SMAAFKNLSAQCQEVRKRKELELQILTEAIRNWEGDDIKTLGNVTYMSQVLIQCAGSEEK B0JZX3_XENTR B0JZX3_XENTR SMTAFKNLSAQCQEVKKKK----------------------------------------- Q6GN51_XENLA Q6GN51_XENLA SMTAFKNLSVR------------------------------------------------- Q4S0P4_TETNG Q4S0P4_TETNG CMAAFKNLSVQCQEVRKRKELELQILTESIRLWEGDDIKTLGSVLYMSQVLVQSPGSEEK B0S771_DANRE B0S771_DANRE CMTAFKNLSAQCQEVRKRKELELQILAETIRLWEGEDIKTLGSVLYMSQAMVQNHGCEEK Q501U3_DANRE Q501U3_DANRE CMTAFKNLSAQCQEVRKRKELELQILAETIRLWEGEDIKTLGSVLYMSQAMVQNHGC-EV MATCH CONSENSUS ???AFK?L??QCQ??RKRK?LELQIL?E?I??WEG??IK?LG?V??MSQ???Q????EEK

Q4RP56_TETNG Q4RP56_TETNG EERYLMLFPNMLVMISASPRMSGFIYQGRFSLTGTVVTRHAEDADSGHYAFDIAGNTIDR ARHG6_CHICK ARHG6_CHICK EERYFLLFSNVLLMLSASPRMSGFIYQGRLPLTGMTLTK-LEDAEGNEHMFEIAGNMMER B7Z667_HUMAN B7Z667_HUMAN ------------------------------------------------------------ Q8N4Q3_HUMAN Q8N4Q3_HUMAN EERYLMLFSNVLIMLSASPRMSGFIYQGKIPIAGTVVTR-LDEIEGNDCTFEITGNTVER ARHG6_HUMAN ARHG6_HUMAN EERYLMLFSNVLIMLSASPRMSGFIYQGKIPIAGTVVTR-LDEIEGNDCTFEITGNTVER B7Z3C7_HUMAN B7Z3C7_HUMAN EERYLMLFSNVLIMLSASPRMSGFIYQGKIPIAGTVVTR-LDEIEGNDCTFEITGNTVER B1AL37_HUMAN B1AL37_HUMAN EERYLMLFSNVLIMLSASPRMSGFIYQGKIPIAGTVVTR-LDEIEGNDCTFEITGNTVER ARHG6_RAT ARHG6_RAT EERYFLLFSSVLIMLSASPRMSGFMYQGKVPIAGMVVTR-LDEIEGNDCTFEITGSTVER ARHG6_MOUSE ARHG6_MOUSE EERYFLLFSSVLIMLSASPRMSGFMYQGKIPIAGMVVNR-LDEIEGSDCMFEITGSTVER A2AFI0_MOUSE A2AFI0_MOUSE EERYFLLFSSVLIMLSASPRMSGFMYQGKIPIAGMVVNR-LDEIEGSDCMFEITGSTVER A2AFJ8_MOUSE A2AFJ8_MOUSE EERYFLLFSSVLIMLSASPRMSGFMYQGKIPIAGMVVNR-LDEIEGSDCMFEITGSTVER A5X7A1_DANRE A5X7A1_DANRE NERYLLLFPHILLMLSASPRMSGFIYQGKLPLTGMSVSK-TEDSDGTKHAFEISGNMIER Q5PRA8_DANRE Q5PRA8_DANRE NERYLLLFPHILLMLSASPRMSGFIYQGKLPLTGMSVSK-TEDSDGTKHAFEISGNMIER A5X7A2_DANRE A5X7A2_DANRE NERYLLLFPHILLMLSASPRMSGFIYQGKLPLTGMSVSK-TEDSDGTKHAFEISGNMIER Q923I5_RAT Q923I5_RAT NERYLLLFPNLLLMLSASPRMSGFIYQGKLPTTGMTITK-LEDSENHRNAFEISGSMIER ARHG7_MOUSE ARHG7_MOUSE NERYLLLFPNLLLMLSASPRMSGFIYQGKLPTTGMTITK-LEDSENHRNAFEISGSMIER ARHG7_RAT ARHG7_RAT NERYLLLFPNLLLMLSASPRMSGFIYQGKLPTTGMTITK-LEDSENHRNAFEISGSMIER A3KMH4_RAT A3KMH4_RAT NERYLLLFPNLLLMLSASPRMSGFIYQGKLPTTGMTITK-LEDSENHRNAFEISGSMIER Q52NK0_RAT Q52NK0_RAT NERYLLLFPNLLLMLSASPRMSGFIYQGKLPTTGMTITK-LEDSENHRNAFEISGSMIER B7Z344_HUMAN B7Z344_HUMAN NERYLLLFPNVLLMLSASPRMSGFIYQGKLPTTGMTITK-LEDSENHRNAFEISGSMIER Q5W9H1_HUMAN Q5W9H1_HUMAN NERYLLLFPNVLLMLSASPRMSGFIYQGKLPTTGMTITK-LEDSENHRNAFEISGSMIER ARHG7_HUMAN ARHG7_HUMAN NERYLLLFPNVLLMLSASPRMSGFIYQGKLPTTGMTITK-LEDSENHRNAFEISGSMIER B7Z6G2_HUMAN B7Z6G2_HUMAN NERYLLLFPNVLLMLSASPRMSGFIYQGKLPTTGMTITK-LEDSENHRNAFEISGSMIER B1ALK7_HUMAN B1ALK7_HUMAN NERYLLLFPNVLLMLSASPRMSGFIYQGKLPTTGMTITK-LEDSENHRNAFEISGSMIER B0JZX3_XENTR B0JZX3_XENTR ------------------------------------------------------------ Q6GN51_XENLA Q6GN51_XENLA ------------------------------------------------------------ Q4S0P4_TETNG Q4S0P4_TETNG SERYLMLFPHVLLLLSASPRMSGFIFQGKLPLAGMSVSK-LEDCEAHKNAFELNGTMFDR B0S771_DANRE B0S771_DANRE NERYLLLFPHVLLILSASPRMSGFIYQGKLPLSGMTVTP-LEDCESHKDAFELSGSMFER Q501U3_DANRE Q501U3_DANRE GQHHIYLFDQ-------------------------------------------------- MATCH CONSENSUS ?ERY??LF???L??LSASPRMSGF?YQG??P??G????????????????FE??G????R

Q4RP56_TETNG Q4RP56_TETNG ITVYCTSAQDLQEWLDNLQPFTKGGSPAGTIAKAVEGKPLSMVGGP-------------- ARHG6_CHICK ARHG6_CHICK ITVSCSTSQDLHEWLEHLQRLTKGT--CNTVSKTQSWSAHSTFG---------------- B7Z667_HUMAN B7Z667_HUMAN ---YC------------------------------------------------------- Q8N4Q3_HUMAN Q8N4Q3_HUMAN IVVHCNNNQDFQEWLEQLNRLIRGPASCSSLSKTSSSSCSAHSSFS-------------- ARHG6_HUMAN ARHG6_HUMAN IVVHCNNNQDFQEWLEQLNRLIRGPASCSSLSKTSSSSCSAHSSFS-------------- B7Z3C7_HUMAN B7Z3C7_HUMAN IVVHCNNNQDFQEWLEQLNRLIRGPASCSSLSKTSSSSCSAHSSFS-------------- B1AL37_HUMAN B1AL37_HUMAN IVVHCNNNQDFQEWLEQLNRLIRGPASCSSLSKTSSSSCSAHSSFS-------------- ARHG6_RAT ARHG6_RAT IVVHCNNNQDFQEWMEQLNRLTKGPASCSSLSKTSSSSCSTHSSFS-------------- ARHG6_MOUSE ARHG6_MOUSE IVVHCNNNQDFQEWMEQLNRLTKGPTSCGSLSKTSSSSCSTHSSFS-------------- A2AFI0_MOUSE A2AFI0_MOUSE IVVHCNNNQDFQEWMEQLNRLTKGPTSCGSLSKTSSSSCSTHSSFS-------------- A2AFJ8_MOUSE A2AFJ8_MOUSE IVVHCNNNQDFQEWMEQLNRLTKGPTSCGSLSKTSSSSCSTHS----------------- A5X7A1_DANRE A5X7A1_DANRE IQVICNNQQDLQDWVDHLHRQTK--RISTSSLKPQSVPCHTLPSHPLTP-SRHSESRGVS Q5PRA8_DANRE Q5PRA8_DANRE IQVICNNQQDLQDWVDHLHRQTK--RISTSSLKPQSVPCHTLPSHPLTP-SRHSESRGVS A5X7A2_DANRE A5X7A2_DANRE IQVICNNQQDLQDWVDHLHRQTK--RISTSSLKPQSVPCHTLPSHPLTP-SRHSESRGVS Q923I5_RAT Q923I5_RAT ILVSCNNQQDLHEWVEHLQRQTKVTSVSNPTIKPHSVPSHTLPSHPLTPSSKHADSKPVA ARHG7_MOUSE ARHG7_MOUSE ILVSCTSQQDLHEWVEHLQKQTKVTSVSNPTIKPHSVPSHTLPSHPLTPSSKHADSKPVA ARHG7_RAT ARHG7_RAT ILVSCNNQQDLHEWVEHLQRQTKVTSVSNPTIKPHSVPSHTLPSHPLTPSSKHADSKPVA A3KMH4_RAT A3KMH4_RAT ILVSCNNQQDLHEWVEHLQRQTKVTSVSNPTIKPHSVPSHTLPSHPLTPSSKHADSKPVA Q52NK0_RAT Q52NK0_RAT ILVSCNNQQDLHEWVEHLQRQTKVTSVSNPTIKPHSVPSHTLPSHPLTPSSKHADSKPVA B7Z344_HUMAN B7Z344_HUMAN ILVSCNNQQDLQEWVEHLQKQTKVTSVGNPTIKPHSVPSHTLPSHPVTPSSKHADSKPAP Q5W9H1_HUMAN Q5W9H1_HUMAN ILVSCNNQQDLQEWVEHLQKQTKVTSVGNPTIKPHSVPSHTLPSHPVTPSSKHADSKPAP ARHG7_HUMAN ARHG7_HUMAN ILVSCNNQQDLQEWVEHLQKQTKVTSVGNPTIKPHSVPSHTLPSHPVTPSSKHADSKPAP B7Z6G2_HUMAN B7Z6G2_HUMAN ILVSCNNQQDLQEWVEHLQKQTKVTSVGNPTIKPHSVPSHTLPSHPVTPSSKHADSKPAP B1ALK7_HUMAN B1ALK7_HUMAN ILVSCNNQQDLQEWVEHLQKQTKVTSVGNPTIKPHSVPSHTLPSHPVTPSSKHADSKPAP B0JZX3_XENTR B0JZX3_XENTR ------------------------------------------------------------ Q6GN51_XENLA Q6GN51_XENLA ------------------------------------------------------------ Q4S0P4_TETNG Q4S0P4_TETNG LQVICTHKQDLQDWVEHLSRQIKHTAATAPSHKPLTVPCHTLPSHPVTP-SRHAEGKAMT B0S771_DANRE B0S771_DANRE LQVICYNKQDLHDWLEHLNRQTKHTTMAAPSMKPLTVPCHTLPSHPLTP-SRHGESRGLT Q501U3_DANRE Q501U3_DANRE ------------------------------------------------------------ MATCH CONSENSUS ??V?C???QD???W???L??????????????K???????????????????????????

Q4RP56_TETNG Q4RP56_TETNG --------THLSHLCS--FSAHSRGPLEPPKISKPWSLSCLRPAPPLKPSAALGYKERMS ARHG6_CHICK ARHG6_CHICK ------------------STGQIRGPLEPPKILKPWSLSCLRPAPPLRPSAALSYKERMS B7Z667_HUMAN B7Z667_HUMAN ------------------------------------------PMLSIRP----------- Q8N4Q3_HUMAN Q8N4Q3_HUMAN ------------------STGQPRGPLEPPQIIKPWSLSCLRPAPPLRPSAALGYKERMS ARHG6_HUMAN ARHG6_HUMAN ------------------STGQPRGPLEPPQIIKPWSLSCLRPAPPLRPSAALGYKERMS B7Z3C7_HUMAN B7Z3C7_HUMAN ------------------STGQPRGPLEPPQIIKPWSLSCLRPAPPLRPSAALGYKERMS B1AL37_HUMAN B1AL37_HUMAN ------------------STGQPRGPLEPPQIIKPWSLSCLRPAPPLRPSAALGYKERMS ARHG6_RAT ARHG6_RAT ------------------STGQPRGPLEPPQIIKPWSLSCLRPAPPLRPSAALGYKERMS ARHG6_MOUSE ARHG6_MOUSE ------------------STGQPRGPLEPPQIIKPWSLSCLRPAPPLRPSAALGYKERMS A2AFI0_MOUSE A2AFI0_MOUSE ------------------STGQPRGPLEPPQIIKPWSLSCLRPAPPLRPSAALGYKE--- A2AFJ8_MOUSE A2AFJ8_MOUSE ------------------------------------------------------------ A5X7A1_DANRE A5X7A1_DANRE GSPVYHTLPHLSSLGTP-HSGMMWGPLEPPKTQKPWSLSCLRPAPPLKPSAALCYKE--- Q5PRA8_DANRE Q5PRA8_DANRE GSPVYHTLPHLSSLGTP-HSGMMWGPLEPPKTQKPWSLSCLRPAPPLKPSAALCYKE--- A5X7A2_DANRE A5X7A2_DANRE GSPVYHTLPHLSSLGTP-HSGMMWGPLEPPKTQKPWSLSCLRPAPPLKPSAALCYKE--- Q923I5_RAT Q923I5_RAT LTPAYHTLPHPSHHGTP-HTTISWGPLEPPKTPKPWSLSCLRPAPPLRPSAALCYKE--- ARHG7_MOUSE ARHG7_MOUSE LTPAYHTLPHPSHHGTP-HTTISWGPLEPPKTPKPWSLSCLRPAPPLRPSAALCYKE--- ARHG7_RAT ARHG7_RAT LTPAYHTLPHPSHHGTP-HTTISWGPLEPPKTPKPWSLSCLRPAPPLRPSAALCYKE--- A3KMH4_RAT A3KMH4_RAT LTPAYHTLPHPSHHGTP-HTTISWGPLEPPKTPKPWSLSCLRPAPPLRPSAALCYKE--- Q52NK0_RAT Q52NK0_RAT LTPAYHTLPHPSHHGTP-HTTISWGPLEPPKTPKPWSLSCLRPAPPLRPSAALCYKE--- B7Z344_HUMAN B7Z344_HUMAN LTPAYHTLPHPSHHGTP-HTTINWGPLEPPKTPKPWSLSCLRPAPPLRPSAALCYKE--- Q5W9H1_HUMAN Q5W9H1_HUMAN LTPAYHTLPHPSHHGTP-HTTINWGPLEPPKTPKPWSLSCLRPAPPLRPSAALCYKE--- ARHG7_HUMAN ARHG7_HUMAN LTPAYHTLPHPSHHGTP-HTTINWGPLEPPKTPKPWSLSCLRPAPPLRPSAALCYKE--- B7Z6G2_HUMAN B7Z6G2_HUMAN LTPAYHTLPHPSHHGTP-HTTINWGPLEPPKTPKPWSLSCLRPAPPLRPSAALCYKE--- B1ALK7_HUMAN B1ALK7_HUMAN LTPAYHTLPHPSHHGTP-HTTINWGPLEPPKTPKPWSLSCLRPAPPLRPSAALCYKE--- B0JZX3_XENTR B0JZX3_XENTR ------------------------------------------------------------ Q6GN51_XENLA Q6GN51_XENLA ------------------------------------------------------------ Q4S0P4_TETNG Q4S0P4_TETNG VAPTYHTLPHPSSHGTSLSSTLMWGPLEPPNTPKPWSLSCLRPAPPLRPSAALCYKE--- B0S771_DANRE B0S771_DANRE VAPAYHTLPHPSSHGTP-HSTMMWGPLEPPKTQKPWSLSCLRPAPPLRPSAALCYKE--- Q501U3_DANRE Q501U3_DANRE ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????GPLEPP???KPWSLSCLRPAPPL?PSAAL?YKE???

Q4RP56_TETNG Q4RP56_TETNG YIMKDSSKSPRPMKKFLPGNRKKERKPSDDEFQIRRSTVALEEDAQILRVIEAYCTGASP ARHG6_CHICK ARHG6_CHICK YILKDSSKSPKTMKKFLP-KRKTERKASDEEFVIRKSTAALEEDAQILKVIEAYCTGAGF B7Z667_HUMAN B7Z667_HUMAN ------------------------------------------------------------ Q8N4Q3_HUMAN Q8N4Q3_HUMAN YILKESSKSPKTMKKFLH-KRKTERKPSEEEYVIRKSTAALEEDAQILKVIEAYCTSANF ARHG6_HUMAN ARHG6_HUMAN YILKESSKSPKTMKKFLH-KRKTERKPSEEEYVIRKSTAALEEDAQILKVIEAYCTSANF B7Z3C7_HUMAN B7Z3C7_HUMAN YILKESSKSPKTMKKFLH-KRKTERKPSEEEYVIRKSTAALEEDAQILKVIEAYCTSANF B1AL37_HUMAN B1AL37_HUMAN YILKESSKSPKTMKKFLH-KRKTERKPSEEEYVIRKSTAALEEDAQILKVIEAYCTSANF ARHG6_RAT ARHG6_RAT YILKESSKSPKTMKKFLH-KRKTERKTSEEEYVIRKSTAALEEDAQILKVIEAYCTSASF ARHG6_MOUSE ARHG6_MOUSE YILKESSKSPKTMKKFLH-KRKTERKASEEEYVIRKSTAALEEDAQILKVIEAYCTSASF A2AFI0_MOUSE A2AFI0_MOUSE ----ESSKSPKTMKKFLH-KRKTERKASEEEYVIRKSTAALEEDAQILKVIEAYCTSASF A2AFJ8_MOUSE A2AFJ8_MOUSE ----ESSKSPKTMKKFLH-KRKTERKASEEEYVIRKSTAALEEDAQILKVIEAYCTSASF A5X7A1_DANRE A5X7A1_DANRE ----DLSKSPKNMKKLLP-KRKPERKPSDEEFAVRKSTAALEEDAQILKVIEAYCTSAKT Q5PRA8_DANRE Q5PRA8_DANRE ----DLSKSPKNMKKLLP-KRKPERKPSDEEFAVRKSTAALEEDAQILKVIEAYCTSAKT A5X7A2_DANRE A5X7A2_DANRE ----DLSKSPKNMKKLLP-KRKPERKPSDEEFAVRKSTAALEEDAQILKVIEAYCTSAKT Q923I5_RAT Q923I5_RAT ----DLSRSPKTMKKLLP-KRKPERKPSDEEFAVRKSTAALEEDAQILKVIEAYCTSAKT ARHG7_MOUSE ARHG7_MOUSE ----DLSKSPKTMKKLLP-KRKPERKPSDEEFAVRKSTAALEEDAQILKVIEAYCTSAKT ARHG7_RAT ARHG7_RAT ----DLSRSPKTMKKLLP-KRKPERKPSDEEFAVRKSTAALEEDAQILKVIEAYCTSAKT A3KMH4_RAT A3KMH4_RAT ----DLSRSPKTMKKLLP-KRKPERKPSDEEFAVRKSTAALEEDAQILKVIEAYCTSAKT Q52NK0_RAT Q52NK0_RAT ----DLSRSPKTMKKLLP-KRKPERKPSDEEFAVRKSTAALEEDAQILKVIEAYCTSAKT B7Z344_HUMAN B7Z344_HUMAN ----DLSKSPKTMKKLLP-KRKPERKPSDEEFASRKSTAALEEDALILKVIEAYCTSAKT Q5W9H1_HUMAN Q5W9H1_HUMAN ----DLSKSPKTMKKLLP-KRKPERKPSMR------------------------------ ARHG7_HUMAN ARHG7_HUMAN ----DLSKSPKTMKKLLP-KRKPERKPSDEEFASRKSTAALEEDAQILKVIEAYCTSAKT B7Z6G2_HUMAN B7Z6G2_HUMAN ----DLSKSPKTMKKLLP-KRKPERKPSDEEFASRKSTAALEEDAQILKVIEAYCTSAKT B1ALK7_HUMAN B1ALK7_HUMAN ----DLSKSPKTMKKLLP-KRKPERKPSDEEFASRKSTAALEEDAQILKVIEAYCTSAKT B0JZX3_XENTR B0JZX3_XENTR ------------------------------------------------------------ Q6GN51_XENLA Q6GN51_XENLA ------------------------------------------------------------ Q4S0P4_TETNG Q4S0P4_TETNG ----DLSKSPKSVKKLLP-KRKPERKQSEEEFALRKSTAALEEDAQILKVIEAYCTSAKT B0S771_DANRE B0S771_DANRE ----DLSKSPKTMKKLLP-KRKPERKPSDEEFALRKSTVALEEDAQILKVIEAYCTSAKT Q501U3_DANRE Q501U3_DANRE ------------------------------------------------------------ MATCH CONSENSUS ??????S?SPK?MKK?L??KRK?ERK?S??E???R?ST?ALEEDA?IL?VIEAYCT?A??

Q4RP56_TETNG Q4RP56_TETNG HQNTTGL----------------------------------LGFLSLDSSLPSWKHKSKL ARHG6_CHICK ARHG6_CHICK QQALSSG----------------------------------------------------- B7Z667_HUMAN B7Z667_HUMAN ------------------------------------------------------------ Q8N4Q3_HUMAN Q8N4Q3_HUMAN QQGHGSS----------------------------------------------------- ARHG6_HUMAN ARHG6_HUMAN QQGHGSS----------------------------------------------------- B7Z3C7_HUMAN B7Z3C7_HUMAN QQGHGSS----------------------------------------------------- B1AL37_HUMAN B1AL37_HUMAN QQGHGSS----------------------------------------------------- ARHG6_RAT ARHG6_RAT QQG--------------------------------------------------------- ARHG6_MOUSE ARHG6_MOUSE QQG--------------------------------------------------------- A2AFI0_MOUSE A2AFI0_MOUSE QQG--------------------------------------------------------- A2AFJ8_MOUSE A2AFJ8_MOUSE QQG--------------------------------------------------------- A5X7A1_DANRE A5X7A1_DANRE RQTLNSR----------------------------------------------------- Q5PRA8_DANRE Q5PRA8_DANRE RQTLNSR----------------------------------------------------- A5X7A2_DANRE A5X7A2_DANRE RQTLNSR----------------------------------------------------- Q923I5_RAT Q923I5_RAT RQTLNSTWQGTDLMHNHVLADDDQSSLDSL------------------------------ ARHG7_MOUSE ARHG7_MOUSE RQTLNSTWQGTDLMHNHVLADDDQSSLDSLGRRSSLSRLE-PSDLSEDSEYDSIWTAHSY ARHG7_RAT ARHG7_RAT RQTLNSS----------------------------------------------------- A3KMH4_RAT A3KMH4_RAT RQTLNSTWQGTDLMHNHVLADDDQSSLDSLGRRSSLSRLE-PSDLSEDSEYDSLWTAHSY Q52NK0_RAT Q52NK0_RAT RQTLNSTWQGTDLMHNHVLADDDQSSLDSLGRRSSLSRLE-PSDLSEDSEYDSLWTAHSY B7Z344_HUMAN B7Z344_HUMAN RQTLNSTWQGTDLMHNHVLADDDQPSLDSL------------------------------ Q5W9H1_HUMAN Q5W9H1_HUMAN ------------------------------------------------------------ ARHG7_HUMAN ARHG7_HUMAN RQTLNSTWQGTDLMHNHVLADDDQPSLDSL------------------------------ B7Z6G2_HUMAN B7Z6G2_HUMAN RQTLNSS----------------------------------------------------- B1ALK7_HUMAN B1ALK7_HUMAN RQTLNSTWQGTDLMHNHVLADDDQPSLDSLGRRSSLSRLE-PSDLSEDSDYDSIWTAHSY B0JZX3_XENTR B0JZX3_XENTR ------------------------------------------------------------ Q6GN51_XENLA Q6GN51_XENLA ------------------------------------------------------------ Q4S0P4_TETNG Q4S0P4_TETNG RQTLNSTWQGTDLMHNHVLADVDRSCADLPGRRSSVSRPELSSDLSEDSDYDSIWTSHSY B0S771_DANRE B0S771_DANRE RQTLNSTWQGTDLMHNHVL---DQSSADSLGRRSSISRPEATSDLSEDSDYDSIWTAHSY Q501U3_DANRE Q501U3_DANRE NQTIKSA----------------------------------------------------- MATCH CONSENSUS ?Q??????????????????????????????????????????????????????????

Q4RP56_TETNG Q4RP56_TETNG PGHLCAAVRKECPPQVLLPEEEKIIVEEMKSNGQTVIEEK-------------------- ARHG6_CHICK ARHG6_CHICK -------SRKDSIPQVLLPEEEKIIIEETRSNGQTVTEEKSLVDTVYALKDEVKELKQEN B7Z667_HUMAN B7Z667_HUMAN ------------------------------------------------------------ Q8N4Q3_HUMAN Q8N4Q3_HUMAN -------TRKDSIPQVLLPEEEKLIIEETRSNGQTIMEEKSLVDTVYALKDEVRELKQEN ARHG6_HUMAN ARHG6_HUMAN -------TRKDSIPQVLLPEEEKLIIEETRSNGQTIMEEKSLVDTVYALKDEVRELKQEN B7Z3C7_HUMAN B7Z3C7_HUMAN -------TRKDSIPQVLLPEEEKLIIEETRSNGQTIMEEKSLVDTVYALKDEVRELKQEN B1AL37_HUMAN B1AL37_HUMAN -------TRKDSIPQVLLPEEEKLIIEETRSNGQTIMEEKSLVDTVYALKDEVRELKQEN ARHG6_RAT ARHG6_RAT -------TRKDSVPQVLLPEEEKLIIEETRSNGQTIIEEKSLVDTVYALKDEVKELKQEN ARHG6_MOUSE ARHG6_MOUSE -------TRKDSVPQVLLPEEEKLIIEETRSNGQTIIEEKSLVDTVYALKDEVKELKQEN A2AFI0_MOUSE A2AFI0_MOUSE -------TRKDSVPQVLLPEEEKLIIEETRSNGQTIIEEKSLVDTVYALKDEVKELKQEN A2AFJ8_MOUSE A2AFJ8_MOUSE -------TRKDSVPQVLLPEEEKLIIEETRSNGQTIIEEKSLVDTVYALKDEVKELKQEN A5X7A1_DANRE A5X7A1_DANRE -------SRKESGPHMLFPEEEKIIVEETKSNGQTVIEERSLVDTVYALRDEVQELKQDN Q5PRA8_DANRE Q5PRA8_DANRE -------SRKESGPHMLFPEEEKIIVEETKSNGQTVIEERSLVDTVYALRDEVQELKQDN A5X7A2_DANRE A5X7A2_DANRE -------SRKESGPHMLFPEEEKIIVEETKSNGQTVIEERSLVDTVYALRDEVQELKQDN Q923I5_RAT Q923I5_RAT -------GRRSSLSRLVPSD----------------LSEDSEYDSLWT----AHSYRMGS ARHG7_MOUSE ARHG7_MOUSE RMGSASRSRKESAPQVLLPEEEKIIVEETKSNGQTVIEEKSLVDTVYALKDEVQELRQDN ARHG7_RAT ARHG7_RAT -------SRKESAPQVLLPEEEKIIVEETKSNGQTVIEEKSLVDTVYALKDEVQELRQDN A3KMH4_RAT A3KMH4_RAT RMGSASRSRKESAPQVLLPEEEKIIVEETKSNGQTVIEEKSLVDTVYALKDEVQELRQDN Q52NK0_RAT Q52NK0_RAT RMGSASRSRKESAPQVLLPEEEKIIVEETKSNGQTVIEEKSLVDTVYALKDEVQELRQDN B7Z344_HUMAN B7Z344_HUMAN -------GRRSSLSRLEPSD----------------LSEDSDYDSIWT----AHSYRMGS Q5W9H1_HUMAN Q5W9H1_HUMAN -------SSRPGKAQLLW------------------------------------------ ARHG7_HUMAN ARHG7_HUMAN -------GRRSSLSRLEPSD----------------LSEDSDYDSIWT----AHSYRMGS B7Z6G2_HUMAN B7Z6G2_HUMAN -------SRKESAPQVLLPEEEKIIVEETKSNGQTVIEEKSLVDTVYALKDEVQELRQDN B1ALK7_HUMAN B1ALK7_HUMAN RMGSTSRSRKESAPQVLLPEEEKIIVEETKSNGQTVIEEKSLVDTVYALKDEVQELRQDN B0JZX3_XENTR B0JZX3_XENTR ------------------------------------------------------------ Q6GN51_XENLA Q6GN51_XENLA ------------------------------------------------------------ Q4S0P4_TETNG Q4S0P4_TETNG RMGSVPRPRTETGLHVIIPGEKKVQVEGPSRNGQSGDDEKSLVDVVYALRDEVQELKQEN B0S771_DANRE B0S771_DANRE RMGSVTRQWKDGSPALIVPGDEKFSVDELKSNGQTLLEEKSLVDVVYALRDEVQELKQDY Q501U3_DANRE Q501U3_DANRE ------------------------------------------------------------ MATCH CONSENSUS ??????????????????????????????????????E?????????????????????

Q4RP56_TETNG Q4RP56_TETNG -------------------------------------------- ARHG6_CHICK ARHG6_CHICK KRMKQCLEEELKSRKDLEKLVRRLLKQTDECSREETGRKSSLIA B7Z667_HUMAN B7Z667_HUMAN ---------------------RKL-------------------- Q8N4Q3_HUMAN Q8N4Q3_HUMAN KRMKQCLEEELKSRRDLEKLVRRLLKQTDECIRGESSSKTSILP ARHG6_HUMAN ARHG6_HUMAN KRMKQCLEEELKSRRDLEKLVRRLLKQTDECIRGESSSKTSILP B7Z3C7_HUMAN B7Z3C7_HUMAN KRMKQCLEEELKSRRDLEKLVRRLLKQTDECIRGESSSKTSILP B1AL37_HUMAN B1AL37_HUMAN KRMKQCLEEELKSRRDLEKLVRRLLKQTDECIRGESSSKTSILP ARHG6_RAT ARHG6_RAT KKMKQCLEEELKSRKDLEKLVRKLLKQTDESIRAESSSKTSILQ ARHG6_MOUSE ARHG6_MOUSE KKMKQCLEEELKSRKDLEKLVRKLLKQTDECIRSESSSKTSILQ A2AFI0_MOUSE A2AFI0_MOUSE KKMKQCLEEELKSRKDLEKLVRKLLKQTDECIRSESSSKTSILQ A2AFJ8_MOUSE A2AFJ8_MOUSE KKMKQCLEEELKSRKDLEKLVRKLLKQTDECIRSESSSKTSILQ A5X7A1_DANRE A5X7A1_DANRE KRIKRTLEEEQKARKELEKVVRRVLKSMNDPSWDETNL------ Q5PRA8_DANRE Q5PRA8_DANRE KRIKRTLEEEQKARKELEKVVRRVLKSMNDPSWDETNL------ A5X7A2_DANRE A5X7A2_DANRE KRIKRTLEEEQKARKELEKVVRRVLKSMNDPSWDETNL------ Q923I5_RAT Q923I5_RAT ASRKSCCSSISHQN------------------------------ ARHG7_MOUSE ARHG7_MOUSE KKMKKSLEEEQRARKDLEKLVRKVLKNMNDPAWDETNL------ ARHG7_RAT ARHG7_RAT KKMKKSLEEEQRARKDLEKLVRKVLKNMNDPAWDETNL------ A3KMH4_RAT A3KMH4_RAT KKMKKSLEEEQRARKDLEKLVRKVLKNMNDPAWDETNL------ Q52NK0_RAT Q52NK0_RAT KKMKKSLEEEQRARKDLEKLVRKVLKNMNDPAWDETNL------ B7Z344_HUMAN B7Z344_HUMAN TSRKSCCSYISHQN------------------------------ Q5W9H1_HUMAN Q5W9H1_HUMAN ---------------------KKMLRF----------------- ARHG7_HUMAN ARHG7_HUMAN TSRKSCCSYISHQN------------------------------ B7Z6G2_HUMAN B7Z6G2_HUMAN KKMKKSLEEEQRARKDLEKLVRKVLKNMNDPAWDETNL------ B1ALK7_HUMAN B1ALK7_HUMAN KKMKKSLEEEQRARKDLEKLVRKVLKNMNDPAWDETNL------ B0JZX3_XENTR B0JZX3_XENTR -------------------------------------------- Q6GN51_XENLA Q6GN51_XENLA -------------------------------------------- Q4S0P4_TETNG Q4S0P4_TETNG KKMKRSLEEEQRARKDLEKVVRKVLKSMNDPTWDETNL------ B0S771_DANRE B0S771_DANRE KKMKKSLEEEQRARKDLERIVKKMLKNMNDPSWDETNL------ Q501U3_DANRE Q501U3_DANRE -------------------------------------------- MATCH CONSENSUS ????????????????????????????????????????????


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