Alignment of the gene Family HBG050748 of HOVERGEN

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Threshold: 50% 80% 100%
Size: Bigger Smaller Normal
Isoforms are ON
B7ZQ97_XENLA B7ZQ97_XENLA ------MAQA-------G-DEWELSKENVQPLRQGRVMSTLQEVLSQQESASHTAVQQQK Q6GPT5_XENLA Q6GPT5_XENLA TRPGQWRSVRVLTMAQAG-DEWELSKENVQPLRQGRVMSTLQEVLSQQESASHTAVQQQK Q8JGT8_XENLA Q8JGT8_XENLA ------MAQA-------G-DEWELSKENVQPLRQGRVMSTLQEVLSQQESASHTAVQQQK Q800D4_CHICK Q800D4_CHICK ------MSRD-------GDDEWELSKENVQPLRQGRVMATLQEALAQQDTSSHTAAQLRK BUB1B_HUMAN BUB1B_HUMAN AAVKKEGGALSEAMSLEG-DEWELSKENVQPLRQGRIMSTLQGALA-QESACNNTLQQQK Q8K2E5_MOUSE Q8K2E5_MOUSE ------MAEASEAMCLEG-AEWELSKENIQPLRHGRVMSTLQGALAKQESAGHTALQQQK BUB1B_MOUSE BUB1B_MOUSE ------MAEASEAMCLEG-AEWELSKENIQPLRHGRVMSTLQGALAKQESAGHTALQQQK A2ARS1_MOUSE A2ARS1_MOUSE ------MAEASEAMCLEG-AEWELSKENIQPLRHGRVMSTLQGALAKQESAGHTALQQQK Q3UZD6_MOUSE Q3UZD6_MOUSE ------MAEASEAMCLEG-AEWELSKENIQPLRHGRVMSTLQGALAKQESAGHTALQQQK MATCH . * ********:****:**:*:*** .*: *::: :.: * :* CONSENSUS ?????????????????G??EWELSKEN?QPLR?GRVMSTLQ??L??QESA?HTA?QQQK

B7ZQ97_XENLA B7ZQ97_XENLA QAFELELRFYAGDDPLDVWDRYIKWAEQAFPQGGKESNLCPLLERGVKIFHEEQRYYDDL Q6GPT5_XENLA Q6GPT5_XENLA QAFELELRFYAGDDPLDVWDRYIKWAEQAFPQGGKESNLCPLLERGVKIFHEEQRYYDDL Q8JGT8_XENLA Q8JGT8_XENLA QAFELELRFYAGDDPLDVWDRYIKWAEQAFPQGGKESNLCPLLERGVKIFHEEQRYYDDL Q800D4_CHICK Q800D4_CHICK QEFESEIRFYSGDDPLDVWDRYIKWTEQTFPQGGKESNLSAVLERAVKALNKQQRYYQDP BUB1B_HUMAN BUB1B_HUMAN RAFEYEIRFYTGNDPLDVWDRYISWTEQNYPQGGKESNMSTLLERAVEALQGEKRYYSDP Q8K2E5_MOUSE Q8K2E5_MOUSE RAFESEIRFYSGDDPLDVWDRYINWTEQNYPQGGKESNMSALVERAIEALQGETRYYNDP BUB1B_MOUSE BUB1B_MOUSE RAFESEIRFYSGDDPLDVWDRYINWTEQNYPQGGKESNMSALVERAIEALQGETRYYNDP A2ARS1_MOUSE A2ARS1_MOUSE RAFESEIRFYSGDDPLDVWDRYINWTEQNYPQGGKESNMSALVERAIEALQGETRYYNDP Q3UZD6_MOUSE Q3UZD6_MOUSE RAFESEIRFYSGDDPLDVWDRYINWTEQNYPQGGKESNMSALVERAIEALQGETRYYNDP MATCH : ** *:***:*:**********.*:** :********:..::**.:: :: : ***.* CONSENSUS ?AFE?E?RFY?GDDPLDVWDRYI?W?EQ??PQGGKESN???L?ER???????E?RYY?D?

B7ZQ97_XENLA B7ZQ97_XENLA RYLNICLKFANFCSEPLDLYSYLHSQGIGVSHSLLYITWAEQFEARGNFKKADSMFQQGM Q6GPT5_XENLA Q6GPT5_XENLA RYLNICLKFANFCSEPLDLYSYLHSQGIGVSHSLLYITWAEQFEARGNFKKADSMFQQGM Q8JGT8_XENLA Q8JGT8_XENLA RYLNICLKFANFCSEPLDLYSYLHSQGIGVSHSLLYITWAEQFEARGNFKKADSMFQQGM Q800D4_CHICK Q800D4_CHICK RYLSLWLKFGNCCNEPLDLYSYLHSQEIGTTLAQLYITWAEELEARGSFKKADIIFQEGL BUB1B_HUMAN BUB1B_HUMAN RFLNLWLKLGRLCNEPLDMYSYLHNQGIGVSLAQFYISWAEEYEARENFRKADAIFQEGI Q8K2E5_MOUSE Q8K2E5_MOUSE RFLSLWIKLGHLCNEPLDMYSYLQSQGIGVSLAQFYISWAEEYEARENFKKADIIFQEGI BUB1B_MOUSE BUB1B_MOUSE RFLSLWIKLGHLCNEPLDMYSYLQSQGIGVSLAQFYISWAEEYEARENFKKADIIFQEGI A2ARS1_MOUSE A2ARS1_MOUSE RFLSLWIKLGHLCNEPLDMYSYLQSQGIGVSLAQFYISWAEEYEARENFKKADIIFQEGI Q3UZD6_MOUSE Q3UZD6_MOUSE RFLSLWIKLGHLCNEPLDMYSYLQSQGIGVSLAQFYISWAEEYEARENFKKADIIFQEGI MATCH *:*.: :*:.. *.****:****:.* **.: : :**:***: *** .*:*** :**:*: CONSENSUS R?L????K????C?EPLD?YSYL?SQGIGVS????YI?WAE??EAR?NFKKAD??FQ?G?

B7ZQ97_XENLA B7ZQ97_XENLA QCKAEPLEKLEIHHRQFQARVSRQVLQGISEGPDVEE--PELSEPQRSSLADLKSRGKTK Q6GPT5_XENLA Q6GPT5_XENLA QCKAEPLEKLEIHHRQFQARVSRQVLQGISEGPDVEE--PELSEPQRSSLADLKSRGKTK Q8JGT8_XENLA Q8JGT8_XENLA QCKAEPLEKLEIHHRQFQARVSRQVLQGISEGPDVEE--PELSEPQRSSLADLKSRGKTK Q800D4_CHICK Q800D4_CHICK NRKAEPLDKLQSHHRQFQTRVSRQTLLGLEEAADEDTGLLETEEPQRSTLADLKGGGKKK BUB1B_HUMAN BUB1B_HUMAN QQKAEPLERLQSQHRQFQARVSRQTLLALEKEEEEEV--FESSVPQRSTLAELKSKGKKT Q8K2E5_MOUSE Q8K2E5_MOUSE ERKAEPLDRLQSQHRQFQSRVSRQAFLALG-NEEEEA--LEPSEPQRSSLAELKSRGKKM BUB1B_MOUSE BUB1B_MOUSE ERKAEPLDRLQSQHRQFQSRVSRQAFLALG-NEEEEA--LEPSEPQRSSLAELKSRGKKM A2ARS1_MOUSE A2ARS1_MOUSE ERKAEPLDRLQSQHRQFQSRVSRQAFLALG-NEEEEA--LEPSEPQRSSLAELKSRGKKM Q3UZD6_MOUSE Q3UZD6_MOUSE ERKAEPLDRLQSQHRQFQSRVSRQAFLALG-NEEEEA--LEPSEPQRSSLAELKSRGKKM MATCH : *****::*: :*****:*****.: .: : : * . ****:**:**. **. CONSENSUS ??KAEPL??L???HRQFQ?RVSRQ???????????E????E?SEPQRS?LA?LKS?GK??

B7ZQ97_XENLA B7ZQ97_XENLA AKVPVNRVGDSIKSRPQGLGLQAAPPQQIPNRSRFSVFDENAAMSAAQELPSLTPQQWTA Q6GPT5_XENLA Q6GPT5_XENLA AKVPVNRVGDSIKSRPQGLGLQAAPPQQIPNRSRFSVFDENAAMSAAQELPSLTPQQWTA Q8JGT8_XENLA Q8JGT8_XENLA AKVPVNRVGDSIKSRPQGLGLQAAPPQQIPNRSRFSVFDENAAMSAAQELPSLTPQQWTA Q800D4_CHICK Q800D4_CHICK VRGSISRVGDALKATNQNRNFQT--PQQFSNNLGFAVFDENSASASGPEIPILTPQHWTE BUB1B_HUMAN BUB1B_HUMAN ARAPIIRVGGALKAPSQNRGLQNPFPQQMQNNSRITVFDENADEASTAELSKPTVQPWIA Q8K2E5_MOUSE Q8K2E5_MOUSE ARAPISRVGSALKAPGQSRGFLNAVPQPVHGNRRITVFDENADTASRPELSKPVAQPWMA BUB1B_MOUSE BUB1B_MOUSE ARAPISRVGGALKAPGQSRGFLNAVPQPVHGNRRITVFDENADTTSRPELSKPVAQPWMA A2ARS1_MOUSE A2ARS1_MOUSE ARAPISRVGGALKAPGQSRGFLNAVPQPVHGNRRITVFDENADTASRTELSKPVAQPWMA Q3UZD6_MOUSE Q3UZD6_MOUSE ARAPISRVGGALKAPGQSRGFLNAVPQPVHGNRRITVFDENADTASRTELSKPVAQPWMA MATCH .: .: ***.::*: *. .: ** . .. ::*****: :: *:. . * * CONSENSUS A??P??RVG???K???Q??G?????PQ??????R??VFDENA??????EL?????Q?W?A

B7ZQ97_XENLA B7ZQ97_XENLA PPPARSKENEQRARPWNSGRP---SRNGHQAPVSELPQSLPSFTPYVDEGAQHQTVTPCK Q6GPT5_XENLA Q6GPT5_XENLA PPPARSKENEQRARPWNSGRP---SRNGHQAPVSELPQSLPSFTPYVDEGAQHQTVTPCK Q8JGT8_XENLA Q8JGT8_XENLA PPPARSKENEQRARPWNSGRP---SRNGHQAPVSELPQSLPSFTPYVDEGAQHQTVTPCK Q800D4_CHICK Q800D4_CHICK PPAPRGKENELSAGPWNSGR----RPRNSANSGVEVPCPMPSFTPYVEESAQQQVMTPCK BUB1B_HUMAN BUB1B_HUMAN PPMPRAKENELQAGPWNTGRSLEHRPRGNTASLIAVPAVLPSFTPYVEETARQPVMTPCK Q8K2E5_MOUSE Q8K2E5_MOUSE PPVPRAKENELQPGPWSTDRPVGRRPHDNPASVTSIPSVLPSFTPYVEESAQQTVMTPCK BUB1B_MOUSE BUB1B_MOUSE PPVPRAKENELQPGPWSTDRPAGRRPHDNPASVTSIPSVLPSFTPYVEESAQQTVMTPCK A2ARS1_MOUSE A2ARS1_MOUSE PPVPRAKENELQPGPWSTDRPAGRRPHDNPASVTSIPSVLPSFTPYVEESAQQTVMTPCK Q3UZD6_MOUSE Q3UZD6_MOUSE PPVPRAKENELQPGPWSTDRPAGRRPHDNPASVTSIPSVLPSFTPYVEESAQQTVMTPCK MATCH ** .*.**** . **.:.* .. . :* :*******:* *:: .:**** CONSENSUS PP??R?KENE????PW???R??????????A?????P??LPSFTPYV?E?AQ????TPCK

B7ZQ97_XENLA B7ZQ97_XENLA INPAVTSVLSSRKPGKDE-DPLQRVQNNSQG---KEETVMYCKDKVYAGVEEFSLEEIRA Q6GPT5_XENLA Q6GPT5_XENLA INPAVTSVLSSRKPGKDE-DPLQRVQNNSQG---KEETVMYCKDKVYAGVEEFSLEEIRA Q8JGT8_XENLA Q8JGT8_XENLA INPAVTSVLSSRKPGKDE-DPLQRVQNNSQG---KEETVMYCKDKVYAGVEEFSLEEIRA Q800D4_CHICK Q800D4_CHICK IEPSINHVLSARKPEKEE-DPLRRVQNHHQDTQEKKEVVMYCKDKVYAGVEEFSFEEIRA BUB1B_HUMAN BUB1B_HUMAN IEPSINHILSTRKPGKEEGDPLQRVQSHQQASEEKKEKMMYCKEKIYAGVGEFSFEEIRA Q8K2E5_MOUSE Q8K2E5_MOUSE IEPSINHVLSTRKPGREEGDPLQRVQSHQQGCEEKKEKMMYCKEKIYAGVGEFSFEEIRA BUB1B_MOUSE BUB1B_MOUSE IEPSINHVLSTRKPGREEGDPLQRVQSHQQGCEEKKEKMMYCKEKIYAGVGEFSFEEIRA A2ARS1_MOUSE A2ARS1_MOUSE IEPSINHVLSTRKPGREEGDPLQRVQSHQQGCEEKKEKMMYCKEKIYAGVGEFSFEEIRA Q3UZD6_MOUSE Q3UZD6_MOUSE IEPSINHVLSTRKPGREEGDPLQRVQSHQQGCEEKKEKMMYCKEKIYAGVGEFSFEEIRA MATCH *:*::. :**:*** ::* ***:***.: * *:* :****:*:**** ***:***** CONSENSUS I?P????VLS?RKPG??E?DPLQRVQ???Q????K?E??MYCK?K?YAGV?EFS?EEIRA

B7ZQ97_XENLA B7ZQ97_XENLA EIYMAKVRRKREDDLQASALRRQDMERQIEEMERQLKGSCIGSKETVIEQPAHNVEPIIT Q6GPT5_XENLA Q6GPT5_XENLA EIYMAKVRRKREDDLQASALRRQDMERQIEEMERQLKGSCIGSKETVIEQPAHNVEPIIT Q8JGT8_XENLA Q8JGT8_XENLA EIYMAKVRRKREDDLQASALRRQDMERQIEEMERQLKGSCIGSKETVIEQPAHNVEPIIT Q800D4_CHICK Q800D4_CHICK EVYRKKAKKKAEEEIQTIAQKKEEIQKKIEELEKKLKEKENHKQQQLHEQPTEVTKPSP- BUB1B_HUMAN BUB1B_HUMAN EVFRKKLKEQREAELLTSAEKRAEMQKQIEEMEKKLKEIQTTQQERTGDQQEETM-PTKE Q8K2E5_MOUSE Q8K2E5_MOUSE EVFRKKLKERREAELLTSAKKREEMQKQIEEMERRLKAMQAVQQEGAGGQQEEKM-PTED BUB1B_MOUSE BUB1B_MOUSE EVFRKKLKERREAELLTSAKKREEMQKQIEEMERRLKAMQAVQQEGAGGQQEEKM-PTED A2ARS1_MOUSE A2ARS1_MOUSE EVFRKKLKERREAELLTSAKKREEMQKQIEEMERRLKAMQAVQQEGAGGQQEEKM-PTED Q3UZD6_MOUSE Q3UZD6_MOUSE EVFRKKLKERREAELLTSAKKREEMQKQIEEMERRLKAMQAVQQEGAGGQQEEKM-PTED MATCH *:: * :.: * :: : * :: :::::***:*::** .:: * . * CONSENSUS E????K????RE??L??SA??R??M??QIEEME??LK???????E????Q??????P???

B7ZQ97_XENLA B7ZQ97_XENLA PCNSKTSESICAPQ---QEPGMEFPLCFE------MADAAPTLPRMGILPVSDVLGNNHN Q6GPT5_XENLA Q6GPT5_XENLA PCNSKTSESICAPQ---QEPGMEFPLCFE------MADAAPTLPRMGILPVSDVLGNNHN Q8JGT8_XENLA Q8JGT8_XENLA PCNSKTSESICAPQ---QEPGMEFPLCFE------MADAAPTLPRMGILPVSDVLGNNHN Q800D4_CHICK Q800D4_CHICK PLGLKERTLSSATELGMKQPHLQSECCLSEDIQLHKLSCSEDTEGGSVFSDSEDEQADQR BUB1B_HUMAN BUB1B_HUMAN TTKLQIA---SESQ---KIPGMTLSSSVC------QVNCCAR----ETSLAENIWQEQPH Q8K2E5_MOUSE Q8K2E5_MOUSE PARLQIA---SGPQ---EMSGVPLSCSIC------PLSSNPR----EISPAENILQEQPD BUB1B_MOUSE BUB1B_MOUSE PARLQIA---SGPQ---EMSGVPLSCSIC------PLSSNPR----EISPAENILQEQPD A2ARS1_MOUSE A2ARS1_MOUSE PARLQIA---SGPQ---EMSGVPLSCSIC------PLSSNPR----EISPAENILQEQPD Q3UZD6_MOUSE Q3UZD6_MOUSE PARLQIA---SGPQ---EMSGVPLSCSIC------PLSSNPR----EISPAENILQEQPN MATCH . : . .: : . : .. .. .: : CONSENSUS P????????????Q??????G???????????????????????????????????????

B7ZQ97_XENLA B7ZQ97_XENLA SSGLSPALSCDMP--------FTIFDES-----SEALPSMSVPKTIAAPVRRPLAVVSKT Q6GPT5_XENLA Q6GPT5_XENLA SSGLSPALSCDMP--------FTIFDES-----SEALPSMSVPKTIAAPVRRPLAVVSKT Q8JGT8_XENLA Q8JGT8_XENLA SSGLSPALSCDMP--------FTIFDES-----SEALPSMSVPKTIAAPVRRPLAVVSKT Q800D4_CHICK Q800D4_CHICK NKANLGKKRCSIPSPTRSATSFSIFDESSTSANQNTSRSTDRGQKTA---RRPLAVRKPS BUB1B_HUMAN BUB1B_HUMAN SKG------PSVP--------FSIFDEFLLSEKKNKSPPADPPRVL-AQ-RRPLAVLKTS Q8K2E5_MOUSE Q8K2E5_MOUSE SKG------SSMP--------FSIFDES-LSDKKDKSPATGGPQVLNAQ-RRPLSVLKTT BUB1B_MOUSE BUB1B_MOUSE SKG------SSMP--------FSIFDES-LSDKKDKSPATGGPQVLNAQ-RRPLSVLKTT A2ARS1_MOUSE A2ARS1_MOUSE SKG------SSMP--------FSIFDES-LSDKKDKSPATGGPQVLNAQ-RRPLSVLKTT Q3UZD6_MOUSE Q3UZD6_MOUSE SKG------SSMP--------FSIFDES-LSDKKDKSPATGGPQVLNAQ-RRPLSVLKTT MATCH ... .:* *:**** .: . . : ****:* . : CONSENSUS S?G?????????P????????F?IFDES?????????P????P????A??RRPL?V????

B7ZQ97_XENLA B7ZQ97_XENLA KS-------ESQLTDTLDGIEHLNEEAIVCGSGKNKSLFPDPEDTCDFVRAAHLASTPFH Q6GPT5_XENLA Q6GPT5_XENLA KS-------ESQLTDTLDGIEHLNEEAIVCGSGKNKSLFPDPEDTCDFVRAAHLASTPFH Q8JGT8_XENLA Q8JGT8_XENLA KS-------ESQLTDTLDGIEHLNEEAIVCGSGKNKSLFPDPEDTCDFVRAAHLASTPFH Q800D4_CHICK Q800D4_CHICK ESITAKENLQPEACDELHGIEPLTEDAIVTGSYKHKSLCANPEDTCDFVRAAHLASTPFH BUB1B_HUMAN BUB1B_HUMAN ESITSNEDVSPDVCDEFTGIEPLSEDAIITG-FRNVTICPNPEDTCDFARAARFVSTPFH Q8K2E5_MOUSE Q8K2E5_MOUSE EVGTTNEDVSPDICDELTELEPLSEDAIITG-FRNVTLCPNPEDTCDFARAARLASTPFH BUB1B_MOUSE BUB1B_MOUSE EVGTTNEDVSPDICDELTELEPLSEDAIITG-FRNVTLCPNPEDTCDFARAARLASTPFH A2ARS1_MOUSE A2ARS1_MOUSE EVGTTNEDVSPDICDELTELEPLSEDAIITG-FRNVTLCPNPEDTCDFARAARLASTPFH Q3UZD6_MOUSE Q3UZD6_MOUSE EVGTTNEDVSPDICDELTELEPLSEDAIITG-FRNVTLCPNPEDTCDFARAARLASTPFH MATCH : ..: * : :* *.*:**: * :: :: .:*******.***::.***** CONSENSUS ??????????????D?L???E?L?E?AI??G???N??L?P?PEDTCDF?RAA?LASTPFH

B7ZQ97_XENLA B7ZQ97_XENLA -------RARDESEESLQRNSAERL--PLQEKTPVCEESYRQELCIKKLSPILEASQEDT Q6GPT5_XENLA Q6GPT5_XENLA -------RARDESEESLQRNSAERL--PLQEKTPVCEESYRQELCIKKLSPILEASQEDT Q8JGT8_XENLA Q8JGT8_XENLA -------RARDESEESLQRNSAERL--PLQEKTPVCEESYRQELCIKKLSPILEASQEDT Q800D4_CHICK Q800D4_CHICK GVVAQRIPAPAYSQSVLKEDCAESKSAPLDEKTPVCEGTYSEALCVNKLSPIMEASLEDT BUB1B_HUMAN BUB1B_HUMAN EIMSLK-DLPSDPERLLPEEDLDVK--TSEDQQTACGTIYSQTLSIKKLSPIIEDSREAT Q8K2E5_MOUSE Q8K2E5_MOUSE EILSSK-GIAADPEGLLQEEDLDGK--AAEAHHTV----HHQALIIKKLSPIIEDSREAT BUB1B_MOUSE BUB1B_MOUSE EILSSK-GIAADPEGLLQEEDLDGK--AAEAHHTV----HHQALIIKKLSPIIEDSREAT A2ARS1_MOUSE A2ARS1_MOUSE EILSSK-GIAADPEGLLQEEDLDGK--AAEAHHTV----HHQALIIKKLSPIIEESREAT Q3UZD6_MOUSE Q3UZD6_MOUSE EILSSK-GIAADPEGLLQEEDLDGK--AAEAHHTV----HHQALIIKKLSPIIEESREAT MATCH .: * .: : . : : .. : : * ::*****:* * * * CONSENSUS ?????????????E??L?????????????????V??????Q?L?IKKLSPI?E?S?E?T

B7ZQ97_XENLA B7ZQ97_XENLA RTSVSSVSS---ISSTTSMFTSKTLPLSEKLELATQITGVYESEPTTEELPQAEEIAELH Q6GPT5_XENLA Q6GPT5_XENLA RTSVSSVSS---ISSTTSMFTSKTLPLSEKLELATQITGVYESEPTTE-LPQAEEIAELH Q8JGT8_XENLA Q8JGT8_XENLA RTSVSSVSS---ISSTTSMFTSKTLPLSEKLELATQITGVYESEPTTEELPQAEEIAELH Q800D4_CHICK Q800D4_CHICK HLSGSSVSSGSSLSSVTQTSTIKYLHIPEKLELAQSLPAEPITDPGGDDATEFLWTAEQR BUB1B_HUMAN BUB1B_HUMAN HSSGFSGSS----ASVASTSSIKCLQIPEKLEL---------TNETSENPTQSPWCSQYR Q8K2E5_MOUSE Q8K2E5_MOUSE HSSGFSRSS----SSAPSTSSIKGFQLLEKLEL---------TNDGAENAIQSPWCSQYR BUB1B_MOUSE BUB1B_MOUSE HSSGFSRSS----SSAPSTSSIKGFQLLEKLEL---------TNDGAENAIQSPWCSQYR A2ARS1_MOUSE A2ARS1_MOUSE HSSGFSRSS----SSAPSTSSIKGFQLLEKLEL---------TNDGAEDAIQSPWCSQYR Q3UZD6_MOUSE Q3UZD6_MOUSE HSSGFSRSS----SSAPSTSSIKGFQLLEKLEL---------TNDGAEDAIQSPWCSQYR MATCH : * * ** :*... : * : : ***** :: : : :: : CONSENSUS ??S??S?SS????SS??S????K?????EKLEL??????????????E???Q????????

B7ZQ97_XENLA B7ZQ97_XENLA RQLLEPLPE-LLVSPEIQHEVGTMPDLKEQEELVLGCETYSLKNEVILHPNSKLFMGAPV Q6GPT5_XENLA Q6GPT5_XENLA RQLLELLPE-LLVSPEIQHEVGTMPDLKEQEELVLGCETYSLKNEVILHPNSKLFMGAPV Q8JGT8_XENLA Q8JGT8_XENLA RQLLELLPE-LLVSPEIQHEVGTMPDLKEQEELVLGCETYSLKNEVILHPNSKLFMGAPV Q800D4_CHICK Q800D4_CHICK KKLLDPMPESLTASPHFHLEAGFLPVIEFEKDIELGNETYCIKREYWTNEEYKMLFAIPV BUB1B_HUMAN BUB1B_HUMAN RQLLKSLPE-LSASAELCIEDRPMPKLEIEKEIELGNEDYCIKREYLICEDYKLFWVAPR Q8K2E5_MOUSE Q8K2E5_MOUSE LQLLKSLLE-ISAFAEFSVEDRPMPVLEIGKEIELGPEDYVIKQEHLTCDDYRLFWVAPR BUB1B_MOUSE BUB1B_MOUSE LQLLKSLLE-LSAFAEFSVEDRPMPVLEIGKEIELGPEDYVIKQEHLTCDDYRLFWVAPR A2ARS1_MOUSE A2ARS1_MOUSE LQLLKSLLE-LSAFAEFSVEDRPMPVLEIGKEIELGPEDYVIKQEHLTCDDYRLFWVAPR Q3UZD6_MOUSE Q3UZD6_MOUSE LQLLKSLLE-LSAFAEFSVEDRPMPVLEIGKEIELGPEDYVIKQEHLTCDDYRLFWVAPR MATCH :**. : * : . ..: * :* :: ::: ** * * :*.* : ::: * CONSENSUS ?QLL??L?E?L????E???E???MP?L????E??LG?E?Y??K?E????????LF??AP?

B7ZQ97_XENLA B7ZQ97_XENLA DWDMEDMKAFALKVDYQPVPWDLYVTMQLKERLGDLFETFFMEQTNCFLYQNGCVRLYKD Q6GPT5_XENLA Q6GPT5_XENLA DWDMEEMKAFALKVDYQPVPWDLYVTLQLKERLGDLFETFFMEQTNCFLYQNGCISLYKD Q8JGT8_XENLA Q8JGT8_XENLA DWDMEEMKAFALKVDYQPVPWDLYVTLQLKERLGDLFETFFMEQTNCFLYQNGCISLYKD Q800D4_CHICK Q800D4_CHICK NFLQLDAKGFAIKVYSQPVPWDFYIMLQLQERLNADFDQSFSGNCSCFLYQDGCAILHKN BUB1B_HUMAN BUB1B_HUMAN NSAELTV----IKVSSQPVPWDFYINLKLKERLNEDFDHF----CSCYQYQDGCIVWHQY Q8K2E5_MOUSE Q8K2E5_MOUSE SSAELTM----IKASSQPIPWDFYINLKLKERLNEDYDQL----CSCCQYQDGHVVWYQY BUB1B_MOUSE BUB1B_MOUSE SSAELTM----IKASSQPIPWDFYINLKLKERLNEDYDQL----CSCCQYQDGHVVWYQY A2ARS1_MOUSE A2ARS1_MOUSE SSAELTM----IKASSQPIPWDFYINLKLKERLNEDYDQL----CSCCQYQDGHVVWYQY Q3UZD6_MOUSE Q3UZD6_MOUSE SSAELTM----IKASSQPIPWDFYINLKLKERLNEDYDQL----CSCCQYQDGHVVWYQY MATCH . :*. **:***:*: ::*:***. :: .* **:* :: CONSENSUS ????????????K???QP?PWD?Y??L?LKERL?????????????C??YQ?G???????

B7ZQ97_XENLA B7ZQ97_XENLA INRFSIQEILLDSEELIKEVIVLVTYNLLSLVEKLHSVEIVHGDLRPETLLLDDKIFDLS Q6GPT5_XENLA Q6GPT5_XENLA INRFSIQEILLDSEELIKEVIVLVTYNLLSLVEKLHSVEIVHGDLRPETLLLDDKIFDLS Q8JGT8_XENLA Q8JGT8_XENLA INRFSIQEILLDSEELIKEVIVLVTYNLLSLVEKLHSVEIVHGDLRPETLLLDDKIFDLS Q800D4_CHICK Q800D4_CHICK INRFTLGDVICGCKSIEEEVILLVVYNLLGVVEKLHKAEIVHGDLRPEIFFLGDRICDPF BUB1B_HUMAN BUB1B_HUMAN INCFTLQDLLQHSEYITHEITVLIIYNLLTIVEMLHKAEIVHGDLSPRCLILRNRIHDPY Q8K2E5_MOUSE Q8K2E5_MOUSE INCSTLQNLLQHSEFVTHEIIVLIIYNLLTIVEKLHRAEIVHGDLSPRSLILRNRIHDPY BUB1B_MOUSE BUB1B_MOUSE INCSTLQNLLQHSEFVTHEIIVLIIYNLLTIVEKLHRAEIVHGDLSPRSLILRNRIHDPY A2ARS1_MOUSE A2ARS1_MOUSE INCSTLQNLLQHSEFVTHEIIVLIIYNLLTIVEKLHRAEIVHGDLSPRSLILRNRIHDPY Q3UZD6_MOUSE Q3UZD6_MOUSE INCSTLQNLLQHSEFVTHEIIVLIIYNLLTIVEKLHRAEIVHGDLSPRSLILRNRIHDPY MATCH ** :: ::: .: : .*: :*: **** :** ** .******* *. ::* ::* * CONSENSUS IN????Q??L??SE????E?IVL??YNLL??VEKLH??EIVHGDL?P??L?L???I?D??

B7ZQ97_XENLA B7ZQ97_XENLA S-SLELEGLFKMVDFSHSMDLKLCPTMSSLRGFPIAQSESGQQFLNPQSSPYQVDLLGIA Q6GPT5_XENLA Q6GPT5_XENLA S-SLELEGLFKMVDFSHSMDLKLCPTMSSLRGFPIAQSESGQQFLNPQSSPYQVDILGIA Q8JGT8_XENLA Q8JGT8_XENLA S-SLELEGLFKMVDFSHSMDLKLCPTMSSLRGFPIAQSESGQQFLNPQSSPYQVDILGIA Q800D4_CHICK Q800D4_CHICK A-NNGMTRALKIVDFSHSLDLRLQSRVSLPNSFPISQTPHGQQLLAKSCLPYQADLVGIA BUB1B_HUMAN BUB1B_HUMAN D-CNKNNQALKIVDFSYSVDLRVQLDVFTLSGFRTVQILEGQKILANCSSPYQVDLFGIA Q8K2E5_MOUSE Q8K2E5_MOUSE DYVNKDDHAVRIMDFSYSVDLRVQLDAFAYSGFRTAQILEGQKILANCSSPYHVDLLGIA BUB1B_MOUSE BUB1B_MOUSE DYVNKDDHAVRIMDFSYSVDLRVQLDAFAYSGFRTAQILEGQKILANCSSPYHVDLLGIA A2ARS1_MOUSE A2ARS1_MOUSE DYVNKDDHAVRIMDFSYSVDLRVQLDAFAYSGFRTAQILEGQKILANCSSPYHVDLLGIA Q3UZD6_MOUSE Q3UZD6_MOUSE DYVNKDDHAVRIMDFSYSVDLRVQLDAFAYSGFRTAQILEGQKILANCSSPYHVDLLGIA MATCH .:::***:*:**:: .* * **::* . **:.*:.*** CONSENSUS ?????????????DFS?S?DL??????????GF???Q???GQ??L???SSPY?VD??GIA

B7ZQ97_XENLA B7ZQ97_XENLA DLVHLMIFRKPLQLNQENSIWTICKEVPRLRGGNLWNQFFTKILNAEGPSTC-VLRELKA Q6GPT5_XENLA Q6GPT5_XENLA DLVHLMIFRKPLQLNQENSVWTICKEVPRLRGGNLWNQFFTKILNAEGPSTC-VLRELKG Q8JGT8_XENLA Q8JGT8_XENLA DLVHLMIFRKPLQLNQENSVWTICKEVPRLRGGNLWNQFFTKILNAEGPSTC-VLRELKG Q800D4_CHICK Q800D4_CHICK DIAHLMLFGEHVQVYQENSVWKISQNVSKTVGSDFWGKFFRQILNADGKSTVLLLRELRE BUB1B_HUMAN BUB1B_HUMAN DLAHLLLFKEHLQVFWDGSFWKLSQNISELKDGELWNKFFVRILNANDEATVSVLGELAA Q8K2E5_MOUSE Q8K2E5_MOUSE DLAHLLLFKEHLHVFWDGLLWKLSQSTSELKDSELWNKFFVRILNASDKSTVSVLGELAA BUB1B_MOUSE BUB1B_MOUSE DLAHLLLFKEHLHVFWDGLLWKLSQSTSELKDSELWNKFFVRILNASDKSTVSVLGELAA A2ARS1_MOUSE A2ARS1_MOUSE DLAHLLLFKEHLHVFWDGLLWKLSQSTSELKDSELWNKFFVRILNASDKSTVSVLGELAA Q3UZD6_MOUSE Q3UZD6_MOUSE DLAHLLLFKEHLHVFWDGLLWKLSQSTSELKDSELWNKFFVRILNASDKSTVSVLGELAA MATCH *:.**::* : ::: :. .*.:.:. .. ..::*.:** :****.. :* :* ** CONSENSUS DL?HL??F???L????????W????????L????LWN?FF??ILNA???ST??VL?EL??

B7ZQ97_XENLA B7ZQ97_XENLA EMMELFDSGFQDKLCNYFIQLEMRLNPL----------------- Q6GPT5_XENLA Q6GPT5_XENLA EMMELFDSGFQDKLCNYFIQLEMRLNPL----------------- Q8JGT8_XENLA Q8JGT8_XENLA EMMELFDSGFQDKLCNYFIQLEMRLNPL----------------- Q800D4_CHICK Q800D4_CHICK EMSDMFDSCFQERLCESLVALGDVFFLEKF--------------- BUB1B_HUMAN BUB1B_HUMAN EMNGVFDTTFQSHLNKALWKVGKLTSPGALLFQ------------ Q8K2E5_MOUSE Q8K2E5_MOUSE EMGGAFDATFHSHLNRALWKLGKTISPEALLTQQDKQPGGSQSPA BUB1B_MOUSE BUB1B_MOUSE EMGGAFDATFHSHLNRALWKLGKTISPEALLTQQDKQPGGSQSPA A2ARS1_MOUSE A2ARS1_MOUSE EMGGAFDATFHSHLNRALWKLGKTISPEALLTQQDKQPGGSQSPA Q3UZD6_MOUSE Q3UZD6_MOUSE EMGGAFDATFHSHLNRALWKLGKTISPEALLTQQDKQPGGSQSPA MATCH ** **: *:.:* . : : CONSENSUS EM???FD??F???L??????L?????P??????????????????


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