Alignment of the gene Family HBG050837 of HOVERGEN

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Threshold: 50% 80% 100%
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Isoforms are ON
Q4RXP3_TETNG Q4RXP3_TETNG -MDRLELQ---EGEREPRREVVHRAVSDRSVTGDARVLQR-LAAVEESCCPASPSLDPVR Q1MTK4_DANRE Q1MTK4_DANRE -MELFCHERADLNSSSPVKSAPIRAFRDAVLTRDTRVLQN-LLSLEKPNI-SGKHIAGAE Q5XJ98_DANRE Q5XJ98_DANRE -MELFCHERADLNSSSPVKSAPIRAFRDAVLTRDTRVLQN-LLSLEKPNI-SGKHIAGAE Q28F81_XENTR Q28F81_XENTR EGRLLCCE---------SVT-ELRARADPVLM-QSRVLMK-LLALEERYIPSASYFRCVQ Q641B3_XENLA Q641B3_XENLA EGNLLCWE---------PET-ELRAQSDPVLL-QSRVLMK-LLELEERYIPSASYFYCVQ Q66IZ3_XENLA Q66IZ3_XENLA EGNVLRW-----------ET-ELKAQEEPVLL-QSRVLMNLLLELEERHIPCISYFHCVQ B2M0W7_MOUSE B2M0W7_MOUSE EHQLLCCE---------VET-IRRAYPDTNLL-NDRVLRA-MLKTEETCAPSVSYFKCVQ Q6GLD3_XENTR Q6GLD3_XENTR -MELLCCE---------VDT-IRRAHLDRNLI-TDRVLQT-MLKAEETCCPNVSYFKCVQ Q7ZYJ6_XENLA Q7ZYJ6_XENLA -MELLCCE---------VDT-IRRAHLDRNLI-TDRVLQT-MLKAEETSCPSVSYFKCVQ CCND1_XENLA CCND1_XENLA -MELLCCE---------VDT-IGRAHLDRNLI-TDRVLQT-MLKAEETSCPSMSYFKCVQ Q8AVQ4_XENLA Q8AVQ4_XENLA -MELLCCE---------VDT-IRRAHLDRNLI-TDRVLQT-MLKAEETSCPSMSYFKCVQ CCND1_CHICK CCND1_CHICK EHQLQCCE---------VET-IRRAYLDANLL-NDRVLQT-MLKAEETCSPSVSYFKCVQ A5A422_CRIGR A5A422_CRIGR EHQLLCCE---------VET-IRRAYPDTNLL-NDRVLRA-MLKTEETCAPSVSYFKCVQ CCND1_RAT CCND1_RAT EHQLLCCE---------VET-IRRAYPDTNLL-NDRVLRA-MLKTEETCAPSVSYFKCVQ CCND1_MOUSE CCND1_MOUSE EHQLLCCE---------VET-IRRAYPDTNLL-NDRVLRA-MLKTEETCAPSVSYFKCVQ Q790L7_MOUSE Q790L7_MOUSE EHQLLCCE---------VET-IRRAYPDTNLL-NDRVLRA-MLKTEETCAPSVSYFKCVQ Q3TC96_MOUSE Q3TC96_MOUSE EHQLLCCE---------VET-IRRAYSDTNLL-NDRVLRA-MLKTEETCAPSVSYFKCVQ CCND1_HUMAN CCND1_HUMAN EHQLLCCE---------VET-IRRAYPDANLL-NDRVLRA-MLKAEETCAPSVSYFKCVQ Q6FI00_HUMAN Q6FI00_HUMAN EHQLLCCE---------VET-IRRAYPDANLL-NDRVLRA-MLKAEETCAPSVSYFKCVQ CCND1_PONAB CCND1_PONAB EHQLLCCE---------VET-IRRAYPDANLL-NDRVLRA-MLKAEETCAPSVSYFKCVQ Q5REV4_PONAB Q5REV4_PONAB EHQLLCCE---------VET-IRRAYPDANLL-NDRVLRA-MLKAEETCAPSVSYFKCVQ CCND1_BOVIN CCND1_BOVIN AHQLLCCE---------MET-IRRAYPDANLL-NDRVLRA-MLKAEETCAPSVSYFKCVQ CCND1_CANFA CCND1_CANFA AHQLLCCE---------VET-IRRAYPDANLL-NDRVLRA-MLKAEETCAPSVSYFKCVQ Q4RZE5_TETNG Q4RZE5_TETNG GEKLLCCE---------VDS-IRRAQQDVNLL-TDRVLLT-MLKAEEHYLPSPNYFKCVQ A7YYE4_DANRE A7YYE4_DANRE EHQLFCCE---------VDT-IRRAYQDSNLL-NDRVLQT-MLKAEENYLPSPNYFKCVQ B2GU16_XENTR B2GU16_XENTR EHQLFCCE---------VDT-IRRAYQDSNLL-NDRVLQT-MLKAEENYLPSPNYFKCVQ CCND1_DANRE CCND1_DANRE EHQLFCCE---------VDT-IRRAYQDSNLL-NDRVLQT-MLKAEENYLPSPNYFKCVQ Q8QFP4_DANRE Q8QFP4_DANRE EHQLFCCE---------VDT-IRRAYQDSNLL-NDRVLQT-MLKAEENYLPSPNYFKCVQ Q5ZKI9_CHICK Q5ZKI9_CHICK -MELLCVE---------TAARVPRAGRDPQLLGDRRVLQN-LLSQEERYSPRVSYFQCVQ B4DRB9_HUMAN B4DRB9_HUMAN -MELLCCE---------GTRHAPRAGPDPRLLGDQRVLQS-LLRLEERYVPRASYFQCVQ CCND3_RAT CCND3_RAT -MELLCCE---------GTRLAPRAGPDPRLLGDQRVLQS-LLRLEERYVPRGSYFQCVQ CCND3_MOUSE CCND3_MOUSE -MELLCCE---------GTRHAPRAGPDPRLLGDQRVLQS-LLRLEERYVPRASYFQCVQ Q3TSW4_MOUSE Q3TSW4_MOUSE -MELLCCE---------GTRHAPRAGPDPRLLGDQRVLQS-LLRLEERYVPRASYFQCVQ Q5U321_RAT Q5U321_RAT -MELLCCE---------GTRHAPRAGPDPRLLGDQRVLQS-LLRLEERYVPRASYFQCVQ Q3TWY0_MOUSE Q3TWY0_MOUSE -MELLCCE---------GTRHAPRAGPDPRLLGDQRVLQS-LLRLEERYVPRASYFQCVQ Q0GMK7_RABIT Q0GMK7_RABIT -----------------------------------------------------------Q B5SNM4_OTOGA B5SNM4_OTOGA -MELLCCE---------STRHAPRAGPDPRLLGDQRVLQS-LLRLEERYVPRASYFQCVQ B2KIE0_RHIFE B2KIE0_RHIFE -MELLCCE---------GTRHAPRAGPDPRLLGDQRVLQS-LLRLEERYVPRASYFQCVQ B3KP19_HUMAN B3KP19_HUMAN ---------------------MKSAGGSGRSL-----------------LPSPR------ A8MN33_PAPAN A8MN33_PAPAN -MELLCCE---------GTRHAPRAGPDPRLLGDQRVLQS-LLRLEERYVPRASYFQCVQ CCND3_HUMAN CCND3_HUMAN -MELLCCE---------GTRHAPRAGPDPRLLGDQRVLQS-LLRLEERYVPRASYFQCVQ Q6FG62_HUMAN Q6FG62_HUMAN -MELLCCE---------GTRHAPRAGPDPRLLGDQRVLQS-LLRLEERYVPRASYFQCVQ Q5T8J1_HUMAN Q5T8J1_HUMAN ---------------------MKSAGGSGRSL-----------------LPSPR------ B3KQ22_HUMAN B3KQ22_HUMAN ------------------------------------------------------------ Q59EI6_HUMAN Q59EI6_HUMAN -TLRHCRG---------GDWLCSDAGRGGEVQSSPR-----GWWLRPPPLPKGRLRRRRD B3KTY3_HUMAN B3KTY3_HUMAN ------------------------------------------------------------ B2MVY3_SHEEP B2MVY3_SHEEP -MELLCCE---------GTRHAPRAGPDPRLLGDQRVLQS-LLRLEERYVPRASYFQCVQ CCND3_BOVIN CCND3_BOVIN -MELLCCE---------GTRHAPRAGPDPRLLGDQRVLQS-LLRLEERYVPRASYFQCVQ Q007T4_PIG Q007T4_PIG -MELLCCE---------GTRHAPRAGPDPRVGGDQRVLQS-LLRLEERYVPRASYFQCVQ Q1L8M6_DANRE Q1L8M6_DANRE -MELFCLE---------KDT-VVRAQKDPNIFCDERVLQS-LLTVEDRYVPQGPYFKCVQ CCND2_MOUSE CCND2_MOUSE -MELLCCE---------VDP-VRRAVPDRNLL-EDRVLQN-LLTIEERYLPQCSYFKCVQ Q4FK45_MOUSE Q4FK45_MOUSE -MELLCCE---------VDP-VRRAVPDRNLL-EDRVLQN-LLTIEERYLPQCSYFKCVQ CCND2_RAT CCND2_RAT -MELLCCE---------VDP-VRRAVPDRNLL-EDRVLQN-LLTIEERYLPQCSYFKCVQ CCND2_HUMAN CCND2_HUMAN -MELLCHE---------VDP-VRRAVRDRNLLRDDRVLQN-LLTIEERYLPQCSYFKCVQ Q53ER2_HUMAN Q53ER2_HUMAN -MELLCHE---------VDP-VRRAVRDRNLLRDDRVLQN-LLTIEERYLPQCSYFKCVQ B2MVY2_SHEEP B2MVY2_SHEEP -MELLCGE---------VEP-VRRAVPDANLLHDDRVLQN-LLTIEERYLPQCSYFKCVQ CCND2_BOVIN CCND2_BOVIN -MELLCGE---------VEP-VRRAVPDANLLHDDRVLQN-LLTIEERYLPQCSYFKCVQ CCND2_PIG CCND2_PIG -MELLCCE---------VDP-VRRAVPDANLLHDDRVLQN-LLTIEERYLPQCSYFKCVQ A3KNN7_DANRE A3KNN7_DANRE -MELLCLE---------MDT-IIRARPDPNLLYDDRVLQS-LLTIEERFLPQCSYFKCVQ O57481_9PERO O57481_9PERO ------------------------------------------------------------ Q4SKE4_TETNG Q4SKE4_TETNG -MELLCLE---------MDS-VIRARPDPNLLADDRILQS-LLTIKERFLPQYSYFKGVQ CCND2_CHICK CCND2_CHICK -MELLCCE---------VDP-MRRALPDPNLLYDDRVLHN-LLTIEERYLPQCSYFKCVQ B7ZQ67_XENLA B7ZQ67_XENLA -MELLCCE---------GDT-VRRAQPDPALLLDDRVLHN-LLTVEERYLPQCSYFKCVQ CCND2_XENLA CCND2_XENLA -MELLCCE---------GDT-VRRAQPDPALLLDDRVLHN-LLTVEERYLPQCSYFKCVQ Q3KPK0_XENLA Q3KPK0_XENLA -MELLCCE---------GDT-VRRAQLDPALLLDDRVLHN-LLTVEERYLPHCSYFKCVQ B5X4N6_SALSA B5X4N6_SALSA -MELICFE----------DK-VVLAKIDPNILYDDRVLQS-LLTIEDRFLPQCSYFKCVQ Q4SAA8_TETNG Q4SAA8_TETNG ------------------------------------------------------------ MATCH CONSENSUS ???L?C?E???????????????RA??D??L????RVL????L??EE???P???YF?CVQ

Q4RXP3_TETNG Q4RXP3_TETNG RDIQPYMRRILVEWMFQVCIWFRNGNKPHSGPTLSVCVCVCVCVCVSVCVQVCEEQQCEE Q1MTK4_DANRE Q1MTK4_DANRE SEELLRMRKILTGWMLQVC----------------------------------EEQKCEE Q5XJ98_DANRE Q5XJ98_DANRE SEELLRMRKILTGWMLQVC----------------------------------EEQKCEE Q28F81_XENTR Q28F81_XENTR RDIQPYMRHMLTCWMLEVC----------------------------------EDQKCGE Q641B3_XENLA Q641B3_XENLA THLQPYMRRMLTSWMLEVC----------------------------------EDQKCGE Q66IZ3_XENLA Q66IZ3_XENLA TRLQPYMRRMLTSWMLEVC----------------------------------EEQKCGE B2M0W7_MOUSE B2M0W7_MOUSE KEIVPSMRKIVATWMLEVC----------------------------------EEQKCEE Q6GLD3_XENTR Q6GLD3_XENTR KEILPHMRKIVATWMLEVC----------------------------------EEQKCEE Q7ZYJ6_XENLA Q7ZYJ6_XENLA KEVLPNMRKIVATWMLEVC----------------------------------EEQKCEE CCND1_XENLA CCND1_XENLA KEILPNMRKIVATWMLEVC----------------------------------EEQKCEE Q8AVQ4_XENLA Q8AVQ4_XENLA KEILPNMRKIVATWMLEVC----------------------------------EEQKCEE CCND1_CHICK CCND1_CHICK KEILPYMRKIVATWMLEVC----------------------------------EEQKCEE A5A422_CRIGR A5A422_CRIGR REIVPSMRKIVATWMLEVC----------------------------------EEQKCEE CCND1_RAT CCND1_RAT REIVPSMRKIVATWMLEVC----------------------------------EEQKCEE CCND1_MOUSE CCND1_MOUSE KEIVPSMRKIVATWMLEVC----------------------------------EEQKCEE Q790L7_MOUSE Q790L7_MOUSE KEIVPSMRKIVATWMLEVC----------------------------------EEQKCEE Q3TC96_MOUSE Q3TC96_MOUSE KEIVPSMRKIVATWMLEVC----------------------------------EEQKCEE CCND1_HUMAN CCND1_HUMAN KEVLPSMRKIVATWMLEVC----------------------------------EEQKCEE Q6FI00_HUMAN Q6FI00_HUMAN KEVLPSMRKIVATWMLEVC----------------------------------EEQKCEE CCND1_PONAB CCND1_PONAB KEVLPSMRKIVATWMLEVC----------------------------------EEQKCEE Q5REV4_PONAB Q5REV4_PONAB KEVLPSMRKIVATWMLEVC----------------------------------EEQKCEE CCND1_BOVIN CCND1_BOVIN KEILPSMRKIVATWMLEVC----------------------------------EEQKCEE CCND1_CANFA CCND1_CANFA KEILPSMRKIVATWMLEVC----------------------------------EEQKCEE Q4RZE5_TETNG Q4RZE5_TETNG KEILPKMRKIVATWMLEVC----------------------------------EEQKCEE A7YYE4_DANRE A7YYE4_DANRE KEIVPKMRKIVATWMLEVC----------------------------------EEQKCEE B2GU16_XENTR B2GU16_XENTR KEIVPKMRKIVATWMLEVC----------------------------------EEQKCEE CCND1_DANRE CCND1_DANRE KEIVPKMRKIVATWMLEVC----------------------------------EEQKCEE Q8QFP4_DANRE Q8QFP4_DANRE KEIVPKMRKIVATWMLEVC----------------------------------EEQKCEE Q5ZKI9_CHICK Q5ZKI9_CHICK REIKPYMRKMLAFWMLEVC----------------------------------EEQKCEE B4DRB9_HUMAN B4DRB9_HUMAN REIKPHMRKMLAYWMLE------------------------------------------- CCND3_RAT CCND3_RAT KEIKPHMRKMLAYWMLEVC----------------------------------EEQRCEE CCND3_MOUSE CCND3_MOUSE KEIKPHMRKMLAYWMLEVC----------------------------------EEQRCEE Q3TSW4_MOUSE Q3TSW4_MOUSE KEIKPHMRKMLAYWMLEVC----------------------------------EEQRCEE Q5U321_RAT Q5U321_RAT KEIKPHMRKMLAYWMLEVC----------------------------------EEQRCEE Q3TWY0_MOUSE Q3TWY0_MOUSE KEIKPHMRKMLTYWMLEVC----------------------------------EEQRCEE Q0GMK7_RABIT Q0GMK7_RABIT REIKPHMRKMLAYWMLEVC----------------------------------EEQRCEE B5SNM4_OTOGA B5SNM4_OTOGA REIKPHMRKMLAYWMLEVC----------------------------------EEQRCEE B2KIE0_RHIFE B2KIE0_RHIFE KEIKPHMRKMLAYWMLEVC----------------------------------EEQRCEE B3KP19_HUMAN B3KP19_HUMAN -----------------VC----------------------------------EEQRCEE A8MN33_PAPAN A8MN33_PAPAN REIKPHMRKMLAYWMLEVC----------------------------------EEQRCEE CCND3_HUMAN CCND3_HUMAN REIKPHMRKMLAYWMLEVC----------------------------------EEQRCEE Q6FG62_HUMAN Q6FG62_HUMAN REIKPHMRKMLAYWMLEVC----------------------------------EEQRCEE Q5T8J1_HUMAN Q5T8J1_HUMAN -----------------VC----------------------------------EEQRCEE B3KQ22_HUMAN B3KQ22_HUMAN ------------------------------------------------------------ Q59EI6_HUMAN Q59EI6_HUMAN RAPATPVGAPGRSPDEEVC----------------------------------EEQRCEE B3KTY3_HUMAN B3KTY3_HUMAN ------------------------------------------------------------ B2MVY3_SHEEP B2MVY3_SHEEP REIKPHMRKMLAYWMLEVC----------------------------------EEQRCEE CCND3_BOVIN CCND3_BOVIN REIKPHMRKMLAYWMLEVC----------------------------------EEQRCEE Q007T4_PIG Q007T4_PIG REIKPHMRKMLAYWMLEVC----------------------------------EEQRCEE Q1L8M6_DANRE Q1L8M6_DANRE KDIQPFMRKMVATWMLEVC----------------------------------EEEKCED CCND2_MOUSE CCND2_MOUSE KDIQPYMRRMVATWMLEVC----------------------------------EEQKCEE Q4FK45_MOUSE Q4FK45_MOUSE KDIQPYMRRMVATWMLEVC----------------------------------EEQKCEE CCND2_RAT CCND2_RAT KDIQPYMRRMVATWMLEVC----------------------------------EEQKCEE CCND2_HUMAN CCND2_HUMAN KDIQPYMRRMVATWMLEVC----------------------------------EEQKCEE Q53ER2_HUMAN Q53ER2_HUMAN KDIQPYMRRMVATWMLEVC----------------------------------EEQKCEE B2MVY2_SHEEP B2MVY2_SHEEP KDIQPYMRRMVATWMLEVC----------------------------------EEQKCEE CCND2_BOVIN CCND2_BOVIN KDIQPYMRRMVATWMLEVC----------------------------------EEQKCEE CCND2_PIG CCND2_PIG KDIQPYMRRMVATWMLEVC----------------------------------EEQKCEE A3KNN7_DANRE A3KNN7_DANRE KDIQPFMRRMVATWMLEVC----------------------------------EEQKCEE O57481_9PERO O57481_9PERO -------------WMLEVC----------------------------------EEQKCGE Q4SKE4_TETNG Q4SKE4_TETNG KDIQPFMRRMVSTWMLEVC----------------------------------QEQKCEE CCND2_CHICK CCND2_CHICK KDIQPFMRRMVATWMLEVC----------------------------------EEQKCEE B7ZQ67_XENLA B7ZQ67_XENLA KDIQPFMRRMVATWMLEVC----------------------------------EEQRCEE CCND2_XENLA CCND2_XENLA KDIQPFMRRMVATWMLEVC----------------------------------EEQRCEE Q3KPK0_XENLA Q3KPK0_XENLA KDIQPFMRRMVATWMLEVC----------------------------------EEQRCEE B5X4N6_SALSA B5X4N6_SALSA KDIQPHMRRMVAGWMHEVC----------------------------------EEEKSEE Q4SAA8_TETNG Q4SAA8_TETNG -----------------VC----------------------------------EEENSNE MATCH CONSENSUS ????P?MR?????WMLEVC??????????????????????????????????EEQ?CEE

Q4RXP3_TETNG Q4RXP3_TETNG EVFPQAVLYLDCYLSRFATGRSDLQLLGAVCMLLASKMRDSVHLTAAKLSIYTDNSVPLS Q1MTK4_DANRE Q1MTK4_DANRE EVFPLAVHYLDRYMSQSAVRPCHLQLLGSVCMFLASKLRETVPLSAETLSIYTDHACSVS Q5XJ98_DANRE Q5XJ98_DANRE EVFPLAVHYLDRYMSQSAVRPCHLQLLGSVCMFLASKLRETVPLSAETLSIYTDHACSVP Q28F81_XENTR Q28F81_XENTR EVFPLAVNCLDRYLSLVPVEKRHLQLLGATCLFLASKLRESKPMTAESLCMYSDHCFTDK Q641B3_XENLA Q641B3_XENLA DVFPLAVNCLDRFLSLVPVEKRRLQLLGSTCLFLASKLRETTPMTAESLCMYSDYCFTDK Q66IZ3_XENLA Q66IZ3_XENLA DVFPLAVNCLDRFLSLVPVEKRHLQLLGSTCLFLASKLRDSTPMTAESLCMYSDYCFTDK B2M0W7_MOUSE B2M0W7_MOUSE EVFPLAMNYLDRFLSLEPLKKSRLQLLGATCMFVASKMKETIPLTAEKLCIYTDNSIRPE Q6GLD3_XENTR Q6GLD3_XENTR EVFPLAMNYLDRFLSVKTLRKSQLQLLGATCMFLASKMKETIPLTAEKLCIYTDNSIRPE Q7ZYJ6_XENLA Q7ZYJ6_XENLA EVFPLAMNYLDRFLSVEPLRKSRLQLLGATCMFLASKMKETIPLTAEKLCIYTDNSIRPD CCND1_XENLA CCND1_XENLA EVFPLAMNYLDRFLSVEPLRKSWLQLLGATCMFLASKMKETIPLTAEKLCIYTDNSIRPD Q8AVQ4_XENLA Q8AVQ4_XENLA EVFPLAMNYLDRFLSVEPLRKSWLQLLGATCMFLASKMKETIPLTAEKLCIYTDNSIRPD CCND1_CHICK CCND1_CHICK EVFPLAMNYLDRFLSFEPLKKSRLQLLGATCMFVASKMKETIPLTAEKLCIYTDNSIRPD A5A422_CRIGR A5A422_CRIGR EVFPLAMNYLDRFLSLEPLKKSRLQLLGATCMFVASKMKETIPLTAEKLCIYTDNSIRPE CCND1_RAT CCND1_RAT EVFPLAMNYLDRFLSLEPLKKSRLQLLGATCMFVASKMKETIPLTAEKLCIYTDNSIRPE CCND1_MOUSE CCND1_MOUSE EVFPLAMNYLDRFLSLEPLKKSRLQLLGATCMFVASKMKETIPLTAEKLCIYTDNSIRPE Q790L7_MOUSE Q790L7_MOUSE EVFPLAMNYLDRFLSLEPLKKSRLQLLGATCMFVASKMKETIPLTAEKLCIYTDNSIRPE Q3TC96_MOUSE Q3TC96_MOUSE EVFPLAMNYLDRFLSLEPLKKSRLQLLGATCMFVASKMKETIPLTAEKLCIYTDNSIRPE CCND1_HUMAN CCND1_HUMAN EVFPLAMNYLDRFLSLEPVKKSRLQLLGATCMFVASKMKETIPLTAEKLCIYTDNSIRPE Q6FI00_HUMAN Q6FI00_HUMAN EVFPLAMNYLDRFLSLEPVKKSRLQLLGATCMFVASKMKETIPLTAEKLCIYTDNSIRPE CCND1_PONAB CCND1_PONAB EVFPLAMNYLDRFLSLEPVKKSRLQLLGATCMFVASKMKETIPLTAEKLCIYTDNSIRPE Q5REV4_PONAB Q5REV4_PONAB EVFPLAMNYLDRFLSLEPVKKSRLQLLGATCMFVASKMKETIPLTAEK--IYTDNSIRPE CCND1_BOVIN CCND1_BOVIN EVFPLAMNYLDRFLSLEPVKKSRLQLLGATCMFVASKMKETIPLTAEKLCIYTDNSIRPD CCND1_CANFA CCND1_CANFA EVFPLAMNYLNRFLSLEPVKKSRLQLLGATCMFVASKMKETIPLTAEKLCIYTDNSIRPD Q4RZE5_TETNG Q4RZE5_TETNG AVFPLAMNYLDRFLSVEATRKTRLQLLGAACMFLASKMKETVPLSAEKLCIYTDNSVRLG A7YYE4_DANRE A7YYE4_DANRE EVFPLAMNYLDRFLSVEPTKKTRLQLLGATCMFLASKMKETVPLTAEKLCIYTDNSVRPG B2GU16_XENTR B2GU16_XENTR EVFPLAMNYLDRFLSVEPTKKTRLQLLGATCMFLASKMKETVPLTAEKLCIYTDNSVRPG CCND1_DANRE CCND1_DANRE EVFPLAMNYLDRFLSVEPTKKTRLQLLGATCMFLASKMKETVPLTAEKLCIYTDNSVRPG Q8QFP4_DANRE Q8QFP4_DANRE EVFPLAMNYLDRFLSVEPTKKNRLQLLGATCMFLASKMKETVPLTAEKLCIYTDNSVRPG Q5ZKI9_CHICK Q5ZKI9_CHICK EVFPLAMNYVDRYLSSVPVRKNHLQLLGAVCMLLASKLRETMPLTVEKLCIYTDNSITPQ B4DRB9_HUMAN B4DRB9_HUMAN ------------------------------------------------------------ CCND3_RAT CCND3_RAT DVFPLAMNYLDRYLSCVPTRKAQLQLLGTVCLLLASKLRETTPLTIEKLCIYTDQAMAPW CCND3_MOUSE CCND3_MOUSE DVFPLAMNYLDRYLSCVPTRKAQLQLLGTVCLLLASKLRETTPLTIEKLCIYTDQAVAPW Q3TSW4_MOUSE Q3TSW4_MOUSE DVFPLAMNYLDRYLSCVPTRKAQLQLLGTVCLLLASKLRETTPLTIEKLCIYTDQAVAPW Q5U321_RAT Q5U321_RAT DVFPLAMNYLDRYLSCVPTRKAQLQLLGTVCLLLASKLRETTPLTIEKLCIYTDQAVAPW Q3TWY0_MOUSE Q3TWY0_MOUSE DVFPLAMNYLDRYLSCVPTRKAQLQLLGTVCLLLASKLRETTPLTIEKLCIYTDQAVAPW Q0GMK7_RABIT Q0GMK7_RABIT EVFPLAMNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPR B5SNM4_OTOGA B5SNM4_OTOGA EVFPLAMNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPR B2KIE0_RHIFE B2KIE0_RHIFE EVFPLAMNYLDRYLSCVPTHKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPR B3KP19_HUMAN B3KP19_HUMAN EVFPLAMNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPR A8MN33_PAPAN A8MN33_PAPAN EVFPLAMNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPR CCND3_HUMAN CCND3_HUMAN EVFPLAMNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPR Q6FG62_HUMAN Q6FG62_HUMAN EVFPLAMNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPR Q5T8J1_HUMAN Q5T8J1_HUMAN EVFPLAMNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPR B3KQ22_HUMAN B3KQ22_HUMAN ------MNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPR Q59EI6_HUMAN Q59EI6_HUMAN EVFPLAMNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPR B3KTY3_HUMAN B3KTY3_HUMAN ------MNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPR B2MVY3_SHEEP B2MVY3_SHEEP EVFPLAMNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHSVSPR CCND3_BOVIN CCND3_BOVIN EVFPLAMNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHSVSPR Q007T4_PIG Q007T4_PIG EVFPLAMNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHSVSPR Q1L8M6_DANRE Q1L8M6_DANRE DVFPLAMNYLDRFLAAVPTRKCYLQLLGAVCLFLASKLKACQPLSARKLCMYTDNSITSQ CCND2_MOUSE CCND2_MOUSE EVFPLAMNYLDRFLAGVPTPKTHLQLLGAVCMFLASKLKETIPLTAEKLCIYTDNSVKPQ Q4FK45_MOUSE Q4FK45_MOUSE EVFPLAMNYLDRFLAGVPTPKTHLQLLGAVCMFLASKLKETIPLTAEKLCIYTDNSVKPQ CCND2_RAT CCND2_RAT EVFPLAMNYLDRFLAGVPTPKTHLQLLGAVCMFLASKLKETIPLTAEKLCIYTDNSVKPQ CCND2_HUMAN CCND2_HUMAN EVFPLAMNYLDRFLAGVPTPKSHLQLLGAVCMFLASKLKETSPLTAEKLCIYTDNSIKPQ Q53ER2_HUMAN Q53ER2_HUMAN EVFPLAMNYLDRFLAGVPTPKSHLQLLGAICMFLASKLKETSPLTAEKLCIYTDNSIKPQ B2MVY2_SHEEP B2MVY2_SHEEP EVFPLAINYLDRFLAGVPTPKTHLQLLGAVCMFLASKLKETIPLTAEKLCIYTDNSIKPQ CCND2_BOVIN CCND2_BOVIN EVFPLAINYLDRFLAGVPTPKTHLQLLGAVCMFLASKLKETIPLTAEKLCIYTDNSIKPQ CCND2_PIG CCND2_PIG EVFPLAINYLDRFLAGVPTPKTHLQLLGAVCMFLASKLKETIPLTAEKLCIYTDNSIKPQ A3KNN7_DANRE A3KNN7_DANRE EVFPLAMNYLDRFLAVVPTRKCNLQLLGAVCMFLASKLKETRPLTAEKLCIYTDNSIRPQ O57481_9PERO O57481_9PERO EVFPLAMNYLDRFLAVVPTKKCNLQLLGAVCMFLASKLKETRPLTAEKLCIYTDNSIRPQ Q4SKE4_TETNG Q4SKE4_TETNG EVFPLAMNYLDRFLAVVPTKKCNLQLLGAVCMFLASKLKETRPLTAEKLCIYTDNSIRPQ CCND2_CHICK CCND2_CHICK EVFPLAMNYLDRFLAVVPTRKCHLQLLGAVCMFLASKLKETIPLTAEKLCIYTDNSIKPQ B7ZQ67_XENLA B7ZQ67_XENLA EVFPMAMNYLDRFLAVIPTRKCHLQLLGAVCMFLASKLKETIPLTAEKLCIYTDNSIKPQ CCND2_XENLA CCND2_XENLA EVFPMAMNYLDRFLAVIPTRKCHLQLLGAVCMFLASKLKETIPLTAEKLCIYTDNSIKPQ Q3KPK0_XENLA Q3KPK0_XENLA EVFPLAMNYLDRFLAVIPTRKSHLQLLGAVCMFLASKLKETIPLTAEKLCIYTDNSIKPQ B5X4N6_SALSA B5X4N6_SALSA DVFPLAINYLDRFLAVEPTRKCYLQLLGAVCMFLATKLKESRPLTAEKLCMYTDNSITPR Q4SAA8_TETNG Q4SAA8_TETNG DVFPLAINYLDRFLAVMPTRKNYLQLLGAVCIFLASKLKDCRPLSAEKLCMYTENSITSR MATCH CONSENSUS ?VFPLAMNYLDR?L???P??K??LQLLGA?CM??ASK??ET?PLT?EKLCIYTD????P?

Q4RXP3_TETNG Q4RXP3_TETNG AILQWELWVVSRLDWCLPSVVPSDFLEPILHGLPFVQPQHLLDMCRHVHAYVALAATGLK Q1MTK4_DANRE Q1MTK4_DANRE EILQWEVLLVSHLQWDLASVLPSDFLELILQALPIPAQDHSS-VRRHTHCYIALTAT--- Q5XJ98_DANRE Q5XJ98_DANRE EILQWEVLLVSHLQWDLASVLPSDFLELILLALPIPAQDHSS-VRRHTHCYIALTAT--- Q28F81_XENTR Q28F81_XENTR ELLAMELLVLNKLKWDLEVVTPREYLPHFLELLNIPAEKRPQ-VRKHSETFIALCTT--- Q641B3_XENLA Q641B3_XENLA ELLAMELLVLNKLKWDIEAVTPREFLPHFLELLGLPTEKRRQ-VRKHSETFIALCTT--- Q66IZ3_XENLA Q66IZ3_XENLA ELLAMELLVLNKLKWDIEAVTPRQFLPHFLELLVIPTEKRPR-VRKLAETFITLCST--- B2M0W7_MOUSE B2M0W7_MOUSE ELLQMELLLVNKLKWNLAAMTPHDFIEHFLSKMPEADENKQT-IRKHAQTFVALCAT--- Q6GLD3_XENTR Q6GLD3_XENTR ELLLMELLILNKLKWDLASVTPHDFIEHFLNKMPLTEDTKQI-IRKHAQTFVALCAT--- Q7ZYJ6_XENLA Q7ZYJ6_XENLA ELLLMELLILNKLKWDLASVTPHDFIEHFLNKMPLTEDTKQI-IRKHAQTFVALCAT--- CCND1_XENLA CCND1_XENLA ELLIMELRVLNKLKWDLASVTPHDFIEHFLNKMPLTEDTKQI-IRKHAQTFVALCAT--- Q8AVQ4_XENLA Q8AVQ4_XENLA ELLIMELRVLNKLKWDLASVTPHDFIEHFLNKMPLTEDTKQI-IRKHAQTFVALCAT--- CCND1_CHICK CCND1_CHICK ELLQMELLLVNKLKWNLAAMTPHDFIEHFLTKMPLAEDTKQI-IRKHAQTFVALCAT--- A5A422_CRIGR A5A422_CRIGR ELLQMELLLVNKLKWNLAAMTPHDFIEHFLSKMPEADENKQI-IRKHAQTFVALCAT--- CCND1_RAT CCND1_RAT ELLQMELLLVNKLKWNLAAMTPHDFIEHFLSKMPEADENKQI-IRKHAQTFVALCAT--- CCND1_MOUSE CCND1_MOUSE ELLQMELLLVNKLKWNLAAMTPHDFIEHFLSKMPEADENKQT-IRKHAQTFVALCAT--- Q790L7_MOUSE Q790L7_MOUSE ELLQMELLLVNKLKWNLAAMTPHDFIEHFLSKMPEADENKQT-IRKHAQTFVALCAT--- Q3TC96_MOUSE Q3TC96_MOUSE ELLQMELLLVNKLKWNLAAMTPHDFIEHFLSKMPEADENKQT-IRKHAQTFVALCAT--- CCND1_HUMAN CCND1_HUMAN ELLQMELLLVNKLKWNLAAMTPHDFIEHFLSKMPEAEENKQI-IRKHAQTFVALCAT--- Q6FI00_HUMAN Q6FI00_HUMAN ELLQMELLLVNKLKWNLAAMTPHDFIEHFLSKMPEAEENKQI-IRKHAQTFVALCAT--- CCND1_PONAB CCND1_PONAB ELLQMELLLVNKLKWNLAALTPHDFIEHFLSKMPEAEENKQI-IRKHAQTFVALCAT--- Q5REV4_PONAB Q5REV4_PONAB ELLQMELLLVNKLKWNLAALTPHDFIEHFLSKMPEAEENKQI-IRKHAQTFVALCAT--- CCND1_BOVIN CCND1_BOVIN ELLHMELVLVNKLKWNLAAMTPHDFIEHFLSKMPVAEENKQI-IRKHAQTFVALCAT--- CCND1_CANFA CCND1_CANFA ELLQMELLLVNKLKWNLAAMTPHDFIEHFLSKMPVAEENKQI-IRKHAQTFVALCAT--- Q4RZE5_TETNG Q4RZE5_TETNG ELLQMELLVLSKLKWDLASVTPHDFIEHFLSKLRIFPSTKHV-LRKHAQTFVALCAT--- A7YYE4_DANRE A7YYE4_DANRE ELLQMELLALNKLKWDLASVTPHDFIEHFLAKLPIHQSSKQI-LRKHAQTFVALCAT--- B2GU16_XENTR B2GU16_XENTR ELLQMELLALNKLKWDLASVTPHDFIEHFLAKLPIHQSSKQI-LRKHAQTFVALCAT--- CCND1_DANRE CCND1_DANRE ELLQMELLALNKLKWDLASVTPHDFIEHFLAKLPIHQSSKQI-LRKHAQTFVALCAT--- Q8QFP4_DANRE Q8QFP4_DANRE ELLQMELLALNKLKWDLASVTPHDFIEHFLAKLPIHQSSKQI-LRKHAQTFVALCAT--- Q5ZKI9_CHICK Q5ZKI9_CHICK QLLDWEILVLEKLKWDLVSVIANDFLAHILHHLPLPKDKMEL-VKKHAQTFIALCAT--- B4DRB9_HUMAN B4DRB9_HUMAN ---DWEVLVLGKLKWDLAAVIAHDFLAFILHRLSLPRDRQAL-VKKHAQTFLALCAT--- CCND3_RAT CCND3_RAT QLREWEVLVLGKLKWDLAAVIAHDFLALILHRLSLPSDRQAL-VKKHAQTFLALCAT--- CCND3_MOUSE CCND3_MOUSE QLREWEVLVLGKLKWDLAAVIAHDFLALILHRLSLPSDRQAL-VKKHAQTFLALCAT--- Q3TSW4_MOUSE Q3TSW4_MOUSE QLREWEVLVLGKLKWDLAAVIAHDFLALILHRLSLPSDRQAL-VKKHAQTFLALCAT--- Q5U321_RAT Q5U321_RAT QLREWEVLVLGKLKWDLAAVIAHDFLALILHRLSLPSDRQAL-VKKHAQTFLALCAT--- Q3TWY0_MOUSE Q3TWY0_MOUSE QLREWEVLVLGKLKWDLAAVIAHDFLALILHRLSLPSDRQAL-VKKHAQTFLALCAT--- Q0GMK7_RABIT Q0GMK7_RABIT QLRDWEALVLGKLKWDLAAVVAHDFLALILHRLSLPSDRQAL-VKKHAQTFLALCAT--- B5SNM4_OTOGA B5SNM4_OTOGA QLRDWEVLVLGKLKWDLAAVIAHDFLALILHRLSLPSDRQAL-VKKHAQTFLALCAT--- B2KIE0_RHIFE B2KIE0_RHIFE QLRDWEVLVLGKLKWDLAAVIAHDFLALILHRLSLPSDRQAL-VKKHAQTFLALCAT--- B3KP19_HUMAN B3KP19_HUMAN QLRDWEVLVLGKLKWDLAAVIAHDFLAFILHRLSLPRDRQAL-VKKHAQTFLALCAT--- A8MN33_PAPAN A8MN33_PAPAN QLRDWEVLVLGKLKWDLAAVIAHDFLALILHRLSLPRDRQAL-VKKHAQTFLALCAT--- CCND3_HUMAN CCND3_HUMAN QLRDWEVLVLGKLKWDLAAVIAHDFLAFILHRLSLPRDRQAL-VKKHAQTFLALCAT--- Q6FG62_HUMAN Q6FG62_HUMAN QLRDWEVLVLGKLKWDLAAVIAHDFLAFILHRLSLPRDRQAL-VKKHAQTFLALCAT--- Q5T8J1_HUMAN Q5T8J1_HUMAN QLRDWEVLVLGKLKWDLAAVIAHDFLAFILHRLSLPRDRQAL-VKKHAQTFLALCAT--- B3KQ22_HUMAN B3KQ22_HUMAN QLRDWEVLVLGKLKWDLAAVIAHDFLAFILHRLSLPRDRQAL-VKKHAQTFLALCAT--- Q59EI6_HUMAN Q59EI6_HUMAN QLRDWEVLVLGKLKWDLAAVIAHDFLAFILHRLSLPRDRQAL-VKKHAQTFLALCAT--- B3KTY3_HUMAN B3KTY3_HUMAN QLRDWEVLVLGKLKWDLAAVIAHDFLAFILHRLSLPRDRQAL-VKKHAQTFLALCAT--- B2MVY3_SHEEP B2MVY3_SHEEP QLRDWEVLVLGKLKWDLAAVIAHDFLALILHRLSLPRDRQAL-VKKHAQTFLALCAT--- CCND3_BOVIN CCND3_BOVIN QLRDWEVLVLGKLKWDLAAVIAHDFLALILHRLSLPRDRQAL-VKKHAQTFLALCAT--- Q007T4_PIG Q007T4_PIG QLRDWEVLVLGKLKWDLAAVIAHDFLALILHRLALPRDRQAL-VKKHAQTFLALCAT--- Q1L8M6_DANRE Q1L8M6_DANRE QLL-WELVVLSKLKWNLAAITPLDFIEHILHKLPFHEDRLTL-IRKHTQTFIALCAT--- CCND2_MOUSE CCND2_MOUSE ELLEWELVVLGKLKWNLAAVTPHDFIEHILRKLPQQKEKLSL-IRKHAQTFIALCAT--- Q4FK45_MOUSE Q4FK45_MOUSE ELLEWELVVLGKLKWNLAAVTPHDFIEHILRKLPQQKEKLSL-IRKHAQTFIALCAT--- CCND2_RAT CCND2_RAT ELLEWELVVLGKLKWNLAAVTPHDFIEHILRKLPQQKEKLSL-IRKHAQTFIALCAT--- CCND2_HUMAN CCND2_HUMAN ELLEWELVVLGKLKWNLAAVTPHDFIEHILRKLPQQREKLSL-IRKHAQTFIALCAT--- Q53ER2_HUMAN Q53ER2_HUMAN ELLEWELVVLGKLKWNLAAVTPHDFIEHILRKLPQQREKLSL-IRKHAQTFIALCAT--- B2MVY2_SHEEP B2MVY2_SHEEP ELLEWELVVLGKLKWNLAAVTPHDFIEHILRKLPQPSEKLSL-IRKHAQTFIALCAT--- CCND2_BOVIN CCND2_BOVIN ELLEWELVVLGKLKWNLAAVTPHDFIEHILRKLPQPSEKLSL-IRKHAQTFIALCAT--- CCND2_PIG CCND2_PIG ELLEWELVVLGKLKWNLAAVTPHDFIEHILRKLPQPNEKLSL-IRKHAQTFIALCAT--- A3KNN7_DANRE A3KNN7_DANRE ELLEWELVVLGKLKWNLAAVTPNDFIEHIMRKLPLPEDKLEL-IRKHVQTFIALCAT--- O57481_9PERO O57481_9PERO ELLEWELVVLGKLKWNLAAVTPNDFIEHIVRRLPLPEDKLAL-IRKHVQTFIALCAT--- Q4SKE4_TETNG Q4SKE4_TETNG ELLEWELVVLGKLKWNLAAVTPNDFIEHIMRRLPLPEDKLAL-IRKHVQTFIALCAT--- CCND2_CHICK CCND2_CHICK ELLEWELVVLGKLKWNLAAVTPHDFIEHILRKLPLPKDKLVL-IRKHAQTFIALCAT--- B7ZQ67_XENLA B7ZQ67_XENLA ELLEWELVVLGKLKWNLAAVTPHDFIEHILRKLPLPKDKLLL-IRKHAQTFIALCAT--- CCND2_XENLA CCND2_XENLA ELLEWELVVLGKLKWNLAAVTPHDFIEHILRKLPLPKDKLLL-IRKHAQTFIALCAT--- Q3KPK0_XENLA Q3KPK0_XENLA ELLEWELVVLGKLKWNLAAVTPHDFIEHILRKLPLPKDKLLL-IRKHAQTFIALCAT--- B5X4N6_SALSA B5X4N6_SALSA ELLEWELVVLGKLKWNMAAVIPNDFVDHILHRLPLPKEKLSV-VRKHTQTFIALCAT--- Q4SAA8_TETNG Q4SAA8_TETNG ELLDWELVVLGKLKWNMASVTPNDFVEHIIRRLPLPKDKLGM-VRKHTQTFVALCAT--- MATCH * : :*.* : : . ::: :: : : : . :::* :* CONSENSUS ?L???E?????KLKW?LA????HDF????L???????????????KHAQTF?ALCAT???

Q4RXP3_TETNG Q4RXP3_TETNG VLVLSIGHRAACLPHVCLSVPDCMFPAFLPSTLACACV--SMASWRLKLVDRGGVPQSVV Q1MTK4_DANRE Q1MTK4_DANRE ------------------------VLVLPP----------VRRGLFLCDGGAA------- Q5XJ98_DANRE Q5XJ98_DANRE ---------------------ELKFSFFRPSVVACSCVTAALLRLKL--LQDTVSAEQML Q28F81_XENTR Q28F81_XENTR ---------------------DCTFIALPPSMVAAASVAAAVTGLQLQSPGPSYSSLASI Q641B3_XENLA Q641B3_XENLA ---------------------DCTFIALPPSMVAAASVVAAVTGLQLQSPGMSNSSVATI Q66IZ3_XENLA Q66IZ3_XENLA ---------------------DCTFITLPPSMVAAACVAAAVTGLQLQSSGMSYSSVATV B2M0W7_MOUSE B2M0W7_MOUSE ---------------------DVKFISNPPSMVAAGSVVAAMQGLNLGSPNNFLSCYRTT Q6GLD3_XENTR Q6GLD3_XENTR ---------------------DIKFISNPPSMIAAGSVAAAVQGLNLGNADSVFSTQRLT Q7ZYJ6_XENLA Q7ZYJ6_XENLA ---------------------DVKFISNPPSMIAAGSVAAAVQGLNLGNADGVFSTQRLT CCND1_XENLA CCND1_XENLA ---------------------DVNFISNPPSMIAAGSVAAAVQGLNLGNADSVFSTQRLT Q8AVQ4_XENLA Q8AVQ4_XENLA ---------------------DVNFISNPPSMIAAGSVAAAVQGLNLGNADSVFSTQRLT CCND1_CHICK CCND1_CHICK ---------------------DVKFISNPPSMIAAGSVVAAVQGLHLGNTNTFLSYQCLT A5A422_CRIGR A5A422_CRIGR ---------------------DVKFISNPPSMVAAGSVVAAMQGLNLGSPNNYLSCYRTT CCND1_RAT CCND1_RAT ---------------------DVKFISNPPSMVAAGSVVAAMQGLNLGSPNNFLSCYRTT CCND1_MOUSE CCND1_MOUSE ---------------------DVKFISNPPSMVAAGSVVAAMQGLNLGSPNNFLSCYRTT Q790L7_MOUSE Q790L7_MOUSE ---------------------DVKFISNPPSMVAAGSVVAAMQGLNLGSPNNFLSCYRTT Q3TC96_MOUSE Q3TC96_MOUSE ---------------------DVKFISNPPSMVAAGSVVAAMQGLNLGSPNNFLSCYRTT CCND1_HUMAN CCND1_HUMAN ---------------------DVKFISNPPSMVAAGSVVAAVQGLNLRSPNNFLSYYRLT Q6FI00_HUMAN Q6FI00_HUMAN ---------------------DVKFISNPPSMVAAGSVVAAVQGLNLRSPNNFLSYYRLT CCND1_PONAB CCND1_PONAB ---------------------DVKFISNPPSMVAAGSVVAAVQGLNLRSPNSFLSYYRLT Q5REV4_PONAB Q5REV4_PONAB ---------------------DVKFISNPPSMVAAGSVVAAVQGLNLRSPNSFLSYYRLT CCND1_BOVIN CCND1_BOVIN ---------------------DVKFISNPPSMVAAGSVAAAAQGLHLGSANGFLSYHRLT CCND1_CANFA CCND1_CANFA ---------------------DVKFISNPPSMVAAGSVVAAVQGLHLGSSNSFLSYHRLT Q4RZE5_TETNG Q4RZE5_TETNG ---------------------DVNFIASPPSMVAAGSVVAAVQGLDLKSLNASFSSQNLT A7YYE4_DANRE A7YYE4_DANRE ---------------------DVNFIASPPSMIAAGSVAAAVQGLYLKSTDSCLSSQNLT B2GU16_XENTR B2GU16_XENTR ---------------------DVNFIASPPSMIAAGSVAAAVQGLYLKSTDSCLSSQNLT CCND1_DANRE CCND1_DANRE ---------------------DVNFIASPPSMIAAGSVAAAVQGLYLKSTDSCLSSQNLT Q8QFP4_DANRE Q8QFP4_DANRE ---------------------DVNFIASPPSMIAAGSVAAAVQGLYLKSTDSCLSSQNLT Q5ZKI9_CHICK Q5ZKI9_CHICK ---------------------DYTFAMYPPSMIATGSISAAVHGLSI--SVNGFGGEAVT B4DRB9_HUMAN B4DRB9_HUMAN -------------------------------------------------------GKSPM CCND3_RAT CCND3_RAT ---------------------DYTFAMYPPSMIATGSIGAAVLGL----GACSMSADELT CCND3_MOUSE CCND3_MOUSE ---------------------DYTFAMYPPSMIATGSIGAAVLGL----GACSMSADELT Q3TSW4_MOUSE Q3TSW4_MOUSE ---------------------DYTFAMYPPSMIATGSIGAAVLGL----GACSMSADELT Q5U321_RAT Q5U321_RAT ---------------------DYTFAMYPPSMIATGSIGAAVLGL----GACSMSADELT Q3TWY0_MOUSE Q3TWY0_MOUSE ---------------------DYTFAMYPPSMIATGSIGAAVLGL----GACSMSADELT Q0GMK7_RABIT Q0GMK7_RABIT ---------------------DYTFAMYPPSMIATGSIGAAVQGL----GACSTSGDELT B5SNM4_OTOGA B5SNM4_OTOGA ---------------------DYTFAMYPPSMIATGSIGAAVQGL----GACPTSGEELT B2KIE0_RHIFE B2KIE0_RHIFE ---------------------DYTFAMYPPSMIATGSIGAAVQGL----GACSISGDELT B3KP19_HUMAN B3KP19_HUMAN ---------------------DYTFVMYPPSMIATGSIGAAVQGL----GACSMSGDELT A8MN33_PAPAN A8MN33_PAPAN ---------------------DYTFAMYPPSMIATGSIGAAVQGL----GACSMSGDELT CCND3_HUMAN CCND3_HUMAN ---------------------DYTFAMYPPSMIATGSIGAAVQGL----GACSMSGDELT Q6FG62_HUMAN Q6FG62_HUMAN ---------------------DYTFAMYPPSMIATGSIGAAVQGL----GACSMSGDELT Q5T8J1_HUMAN Q5T8J1_HUMAN ---------------------DYTFAMYPPSMIATGSIGAAVQGL----GACSMSGDELT B3KQ22_HUMAN B3KQ22_HUMAN ---------------------DYTFAMYPPSMIATGSIGAAVQGL----GACSMSGDELT Q59EI6_HUMAN Q59EI6_HUMAN ---------------------DYTFAMYPPSMIATGSIGAAVQGL----GACSMSGDELT B3KTY3_HUMAN B3KTY3_HUMAN ---------------------DYTFAMYPPSMIATGSIGAAVQGL----GACSMSGDELT B2MVY3_SHEEP B2MVY3_SHEEP ---------------------DYTFAMYPPSMIATGSIGAAVQGL----GACSTSGDELT CCND3_BOVIN CCND3_BOVIN ---------------------DYTFAMYPPSMIATGSIGAAVQGL----GACSTSGDELT Q007T4_PIG Q007T4_PIG ---------------------DYTFAMYPPSMIATGSIGAAVQGL----GACSTSGDELT Q1L8M6_DANRE Q1L8M6_DANRE ---------------------DHSFTMYPPSMIATGCVGAAVCGLQSSQSNQSLWGDNLM CCND2_MOUSE CCND2_MOUSE ---------------------DFKFAMYPPSMIATGSVGAAICGLQQDDEVNTLTCDALT Q4FK45_MOUSE Q4FK45_MOUSE ---------------------DFKFAMYPPSMIATGSVGAAICGLQQDDEVNTLTCDALT CCND2_RAT CCND2_RAT ---------------------DFKFAMYPPSMIATGSVGAAICGLQQDEEVNALTCDALT CCND2_HUMAN CCND2_HUMAN ---------------------DFKFAMYPPSMIATGSVGAAICGLQQDEEVSSLTCDALT Q53ER2_HUMAN Q53ER2_HUMAN ---------------------DFKFAMYPPSMIATGSVGAAICGLQQDEEVSSLTCDALT B2MVY2_SHEEP B2MVY2_SHEEP ---------------------DFKFAMYPPSMIATGSVGAAICGLQQDEDVSSLTGDALV CCND2_BOVIN CCND2_BOVIN ---------------------DFKFAMYPPSMIATGSVGAAICGLQQDEDVSSLTGDALV CCND2_PIG CCND2_PIG ---------------------DFKFAMYPPSMIATGSVGAAICGLQQDEDVSSLTGDALV A3KNN7_DANRE A3KNN7_DANRE ---------------------DFNFAMYPPSMIATGSVAAAICGLQLNSTNHSLWGDNLT O57481_9PERO O57481_9PERO ---------------------DFRFAMYPPSMIATGSVGAAICGLQLDSADQSQWGDSLT Q4SKE4_TETNG Q4SKE4_TETNG ---------------------DFRFAMYPPSMIATGSVGAAICGLQLDSANQSQWGESLT CCND2_CHICK CCND2_CHICK ---------------------DFNFAMYPPSMIATGSVGAAICGLQLDDGDRSLSGDSLT B7ZQ67_XENLA B7ZQ67_XENLA ---------------------DFNFAMYPPSMIATGSVGAAICGLQLDVGETSLSGDSLT CCND2_XENLA CCND2_XENLA ---------------------DFNFAMYPPSMIATGSVGAAICGLQLDVGETSLSGDSLT Q3KPK0_XENLA Q3KPK0_XENLA ---------------------DFNFAMYPPSMIATGSVGAAICGLQLDDGETSLSGDSLT B5X4N6_SALSA B5X4N6_SALSA ---------------------DFSFAMNPPSMIATGSVGAAVCGLQLDQSDQALSRDRLT Q4SAA8_TETNG Q4SAA8_TETNG ---------------------DDRLAMNPPSMIATGSMGAAVCGLQLDRADARLSRDNLT MATCH CONSENSUS ?????????????????????D??F???PPSM?A?GS??AA??GL??????????????T

Q4RXP3_TETNG Q4RXP3_TETNG LVLAQLLSTDASSILLCYH-HLG--------------SLLEEKMPSLLHQGPGLG----- Q1MTK4_DANRE Q1MTK4_DANRE ------------------------------------------------------------ Q5XJ98_DANRE Q5XJ98_DANRE QMLSNMLDMDKASLHVCFS-ALE--------------QMIEQTL---------PA----- Q28F81_XENTR Q28F81_XENTR NLLAHAIHCDPSLLRACQE-QIE--------------ISLESSVQRAQRNRVSES----- Q641B3_XENLA Q641B3_XENLA TYLAHAIRCDPSLLRTCQE-QIE--------------MSLESSLQQAQRNRISES----- Q66IZ3_XENLA Q66IZ3_XENLA TFLAHAIRCEPSLLRTCQE-QIE--------------ISLESSLQEAQRNRISES----- B2M0W7_MOUSE B2M0W7_MOUSE HFLSRVIKCDP-VSKSHQR-RLQLARAWEPWWAVPRHCVTGLELRGA--KSGSPR---AS Q6GLD3_XENTR Q6GLD3_XENTR LFLSQVIKCDPDCLRACQE-QIE--------------SLLESSLRQAQQQHNTSS----- Q7ZYJ6_XENLA Q7ZYJ6_XENLA LFLSQVIKCDPDCLRACQE-QIE--------------SLLESSLRQAQQQHNTSS----- CCND1_XENLA CCND1_XENLA LFLSQVIKCDPDCLRACQE-QIE--------------SLLESSLRQAQQQHNASS----- Q8AVQ4_XENLA Q8AVQ4_XENLA LFLSQVIKCDPDCLRACQE-QIE--------------SLLESSLRQAQQQHNASS----- CCND1_CHICK CCND1_CHICK HFLSQVIKCDPDCLRACQE-QIE--------------SLLESSLRQAQQHNVSSE----- A5A422_CRIGR A5A422_CRIGR HFLSRVIKCDPDCLRACQE-QIE--------------ALLESSLRQA-QQNINPK---AT CCND1_RAT CCND1_RAT HFLSRVIKCDPDCLRACQE-QIE--------------ALLESSLRQA-QQNIDPK---AT CCND1_MOUSE CCND1_MOUSE HFLSRVIKCDPDCLRACQE-QIE--------------ALLESSLRQA-QQNVDPK---AT Q790L7_MOUSE Q790L7_MOUSE HFLSRVIKCDPDCLRACQE-QIE--------------ALLESSLRQA-QQNVDPK---AT Q3TC96_MOUSE Q3TC96_MOUSE HFLSRVIKCDPDCLRACQE-QIE--------------ALLESSLRQA-QQNVDPK---AT CCND1_HUMAN CCND1_HUMAN RFLSRVIKCDPDCLRACQE-QIE--------------ALLESSLRQA-QQNMDPK---AA Q6FI00_HUMAN Q6FI00_HUMAN RFLSRVIKCDPDCLRACQE-QIE--------------ALLESSLRQA-QQNMDPK---AA CCND1_PONAB CCND1_PONAB RFLSRVIKCDPDCLRACQE-QIE--------------ALLESSLRQA-QQNMDPK---AA Q5REV4_PONAB Q5REV4_PONAB RFLSRVIKCDPDCLRACQE-QIE--------------ALLESSLRQA-QQNMDPK---AA CCND1_BOVIN CCND1_BOVIN RFLSKVIRCDPDCLRACQE-QIE--------------ALLESSLRQAQQQNLDPK----A CCND1_CANFA CCND1_CANFA RFLSKVIKCDADCLRACQE-QIE--------------ALLESSLRQAQQQSLDPK----A Q4RZE5_TETNG Q4RZE5_TETNG NLLSQVIGSDPDCLRACQE-QIE--------------SLLVSSLQQAQHHSSTTE----- A7YYE4_DANRE A7YYE4_DANRE NFLSQVIRSDPDCLRSCQE-QIE--------------SLLESSLRQAQQHISTET----- B2GU16_XENTR B2GU16_XENTR NFLSQVIRSDPDCLRSCQE-QIE--------------SLLESSLRQAQQHISTET----- CCND1_DANRE CCND1_DANRE NFLSQVIRSDPDCLRSCQE-QIE--------------SLLESSLRQAQQHISTET----- Q8QFP4_DANRE Q8QFP4_DANRE NFLSQVIRSDPDCLRSCQE-QIE--------------SLLESSLRQAQQHISTET----- Q5ZKI9_CHICK Q5ZKI9_CHICK ELLAGITGTEVDCLKACQE-QIE--------------AALAESLKQASQSQQEYS----- B4DRB9_HUMAN B4DRB9_HUMAN HIFAKLEKSE-------------------------------------------------- CCND3_RAT CCND3_RAT ELLAGITGTEVDCLRACQEQQIE--------------AALRESLREAAQTAPSPV---PK CCND3_MOUSE CCND3_MOUSE ELLAGITGTEVDCLRACQE-QIE--------------AALRESLREAAQTAPSPV---PK Q3TSW4_MOUSE Q3TSW4_MOUSE ELLAGITGTEVDCLRACQE-QIE--------------AALRESLREAAQTAPSPV---PK Q5U321_RAT Q5U321_RAT ELLAGITGTEVDCLRACQE-QIE--------------AALRESLREAAQTAPSPV---PK Q3TWY0_MOUSE Q3TWY0_MOUSE ELLAGITGTEVDCLRACQE-QIE--------------AALRESLREAAQTAPSPV---PK Q0GMK7_RABIT Q0GMK7_RABIT ELLAGITGTEVDCLRACQE-QIE--------------AALRESLREASQTT--------- B5SNM4_OTOGA B5SNM4_OTOGA ELLAGITGTEVDCLRACQE-QIE--------------AALRESLREAAQTSSSPA---PK B2KIE0_RHIFE B2KIE0_RHIFE ELLAGITGTEVDCLRACQE-QIE--------------AALRESLREAAKTSPSPA---PK B3KP19_HUMAN B3KP19_HUMAN ELLAGITGTEVDCLRACQE-QIE--------------AALRESLREAAQTSSSPA---PK A8MN33_PAPAN A8MN33_PAPAN ELLAGITGTEVDCLRACQE-QIE--------------AALRESLREAAQTSSSPA---PK CCND3_HUMAN CCND3_HUMAN ELLAGITGTEVDCLRACQE-QIE--------------AALRESLREASQTSSSPA---PK Q6FG62_HUMAN Q6FG62_HUMAN ELLAGITGTEVDCLRACQE-QIE--------------AALRESLREAAQTSSSPA---PK Q5T8J1_HUMAN Q5T8J1_HUMAN ELLAGITGTEVDCLRACQE-QIE--------------AALRESLREASQTSSSPA---PK B3KQ22_HUMAN B3KQ22_HUMAN ELLAGITGTEVDCLRACQE-QIE--------------AALRESLREASQTSSSPA---PK Q59EI6_HUMAN Q59EI6_HUMAN ELLAGITGTEVDCLRACQE-QIE--------------AALRESLREAAQTSSSPA---PK B3KTY3_HUMAN B3KTY3_HUMAN ELLAGITGTEVDCLRACQE-QIE--------------AALRESLREAAQTSSSPA---PK B2MVY3_SHEEP B2MVY3_SHEEP ELLAGITGTEVDCLRACQE-QIE--------------AALRESLREAAQTSPSPA---PK CCND3_BOVIN CCND3_BOVIN ELLAGIAGTEVDCLRACQE-QIE--------------AALRESLREAAQTSPSPA---PK Q007T4_PIG Q007T4_PIG ELLAGITGTEVDCLRACQE-QIE--------------AALRESLREAAQTSPSPA---PK Q1L8M6_DANRE Q1L8M6_DANRE ELLAKITNTELDCLKSCQE-QIE--------------QLLTDSLKESQQQHQQQQ--QDG CCND2_MOUSE CCND2_MOUSE ELLAKITHTDVDCLKACQE-QIE--------------ALLLNSLQQFRQEQHNAG----- Q4FK45_MOUSE Q4FK45_MOUSE ELLAKITHTDVDCLKACQE-QIE--------------ALLLNSLQQFRQEQHNAG----- CCND2_RAT CCND2_RAT ELLTKITHTDVDCLKACQE-QIE--------------AVLLNSLQQFRQEQHNGS----- CCND2_HUMAN CCND2_HUMAN ELLAKITNTDVDCLKACQE-QIE--------------AVLLNSLQQYRQDQRDGS----- Q53ER2_HUMAN Q53ER2_HUMAN ELLAKITNTDVDCLKACQE-QIE--------------AVLLNSLQQYRQDQRDGS----- B2MVY2_SHEEP B2MVY2_SHEEP DLLAKITNTDVDCLKACQE-QIE--------------VVLLNSLQQYRQDQGDGS----- CCND2_BOVIN CCND2_BOVIN DLLAKITNTDVDCLKACQE-QIE--------------VVLLNSLQQYRQDQGDGS----- CCND2_PIG CCND2_PIG DLLARITNTDVDCLKACQE-QIE--------------VVLLNSLQQYRQDQDGSK----- A3KNN7_DANRE A3KNN7_DANRE ELLAKITNTEVDVLKACQE-QIE--------------RVLMNNLREGRRQQQKQQQQEQG O57481_9PERO O57481_9PERO DLLAKITNTEVDVLKECQE-QIE------------------------------------- Q4SKE4_TETNG Q4SKE4_TETNG ELLAKITNTEVDVLKACQE-QIE--------------RVLLSSLREGRQQQQQHQ-QTQR CCND2_CHICK CCND2_CHICK DFLAKITSTDVDCLKACQE-QIE--------------SVLVSNLRQVRQQQQQSN----- B7ZQ67_XENLA B7ZQ67_XENLA EHLAKITSTDVDCLKACQE-QIE--------------SVLVSSLRQTRQQTQQRN----- CCND2_XENLA CCND2_XENLA EHLAKITSTDVDCLKACQE-QIE--------------SVLVSSLRQTRQQTQQRN----- Q3KPK0_XENLA Q3KPK0_XENLA EHLAKITSTDVDCLKACQE-QIE--------------SVLVRSLRQTRQQAQQRN----- B5X4N6_SALSA B5X4N6_SALSA DLLAKITNTEVDCLKACQE-QIE--------------RVLASSLQQRQEALGRPG-SKAM Q4SAA8_TETNG Q4SAA8_TETNG DLLAKITNTEVDCLRACQE-QIE--------------RVLAASLRQGPQYQLEKG----V MATCH CONSENSUS ??L????????DCL?ACQE?QIE????????????????L??SL????Q???????????

Q4RXP3_TETNG Q4RXP3_TETNG --------------------------- Q1MTK4_DANRE Q1MTK4_DANRE --------------------------- Q5XJ98_DANRE Q5XJ98_DANRE -----------------PPVQTQDVPL Q28F81_XENTR Q28F81_XENTR ----KSVDEPERSS---TPTDVQDIDL Q641B3_XENLA Q641B3_XENLA ----KSVDEPERSS---TPTDVLDIDL Q66IZ3_XENLA Q66IZ3_XENLA ----KSVEEPERSS---TPTDVLDIDL B2M0W7_MOUSE B2M0W7_MOUSE SQSHGSQRHRGLWCGDSAPAMCMGSGM Q6GLD3_XENTR Q6GLD3_XENTR -DTKNMVEEADISC---TPTDVRDVNI Q7ZYJ6_XENLA Q7ZYJ6_XENLA -DTKNMEEEVDISC---TPTDVRDVNI CCND1_XENLA CCND1_XENLA -DTKNMVDEVDISC---TPTDVRDVNI Q8AVQ4_XENLA Q8AVQ4_XENLA -DTKNMVDEVDISC---TPTDVRDVNI CCND1_CHICK CCND1_CHICK --TKTVEDEADLSC---TPTDVRDVNI A5A422_CRIGR A5A422_CRIGR EEEGEAEGETDLAC---TPTDVRDVDI CCND1_RAT CCND1_RAT EEEGEVEEEAGLAC---TPTDVRDVDI CCND1_MOUSE CCND1_MOUSE EEEGEVEEEAGLAC---TPTDVRDVDI Q790L7_MOUSE Q790L7_MOUSE EEEGEVEEEAGLAC---TPTDVRDVDI Q3TC96_MOUSE Q3TC96_MOUSE EEEGEVEEEAGLAC---TPTDVRDVDI CCND1_HUMAN CCND1_HUMAN EEEEEEEEEVDLAC---TPTDVRDVDI Q6FI00_HUMAN Q6FI00_HUMAN EEEEEEEEEVDLAC---TPTDVRDVDI CCND1_PONAB CCND1_PONAB EEEEEEEEEVDLAC---TPTDVRDVDI Q5REV4_PONAB Q5REV4_PONAB -EEEEEEEEVDLAC---TPTDVRDVDI CCND1_BOVIN CCND1_BOVIN AEEEEEEEEVDLAC---TPTDVRDVNI CCND1_CANFA CCND1_CANFA AEEEEEEEEADLAC---TPTDVRDVNI Q4RZE5_TETNG Q4RZE5_TETNG --PKRVSADADLSC---TPTDVRDVNI A7YYE4_DANRE A7YYE4_DANRE ---KRVEEDVDLSC---TPTDVRDINI B2GU16_XENTR B2GU16_XENTR ---KRVEEDVDLSC---TPTDVRDINI CCND1_DANRE CCND1_DANRE ---KRVEEDVDLSC---TPTDVRDINI Q8QFP4_DANRE Q8QFP4_DANRE ---KRVEEDVDLSC---TPTDVRDINI Q5ZKI9_CHICK Q5ZKI9_CHICK TAKTAAYPASQPTS---TPTDVTDINL B4DRB9_HUMAN B4DRB9_HUMAN -------------------------DL CCND3_RAT CCND3_RAT APGGSSSQGPSQTS---TPTDVTAIHL CCND3_MOUSE CCND3_MOUSE APRGSSSQGPSQTS---TPTDVTAIHL Q3TSW4_MOUSE Q3TSW4_MOUSE APRGSSSQGPSQTS---TPTDVTAIHL Q5U321_RAT Q5U321_RAT APRGSSSQGPSQTS---TPTDVTAIHL Q3TWY0_MOUSE Q3TWY0_MOUSE APRGSSSQGPSQTS---TPTDVTAIHL Q0GMK7_RABIT Q0GMK7_RABIT --------------------------- B5SNM4_OTOGA B5SNM4_OTOGA APRGSSSQGPTQTS---TPTDVTAIHL B2KIE0_RHIFE B2KIE0_RHIFE APRGSSSQGPSQTS---TPTDVTAIHL B3KP19_HUMAN B3KP19_HUMAN APRGSSSQGPSQTS---TPTDVTAIHL A8MN33_PAPAN A8MN33_PAPAN APRGSSSQGPSQTS---TPTDVTAIHL CCND3_HUMAN CCND3_HUMAN APRGSSSQGPSQTS---TPTDVTAIHL Q6FG62_HUMAN Q6FG62_HUMAN APRGSSSQGPSQTS---TPTDVTAIHL Q5T8J1_HUMAN Q5T8J1_HUMAN APRGSSSQGPSQTS---TPTDVTAIHL B3KQ22_HUMAN B3KQ22_HUMAN APRGSSSQGPSQTS---TPTDVTAIHL Q59EI6_HUMAN Q59EI6_HUMAN APRGSSSQGPSQTS---TPTDVTAIHL B3KTY3_HUMAN B3KTY3_HUMAN APRGSSSQGPSQTS---TPTDVTAIHL B2MVY3_SHEEP B2MVY3_SHEEP APRVSSSQGPSQTS---TPTDVTAIHL CCND3_BOVIN CCND3_BOVIN APRGSSSQGPSQTS---TPTDVTAIHL Q007T4_PIG Q007T4_PIG APRGSSSQGPSQTS---TPTDVTAIHL Q1L8M6_DANRE Q1L8M6_DANRE RASNKGTQSQNLSC---TPTDVRDVNL CCND2_MOUSE CCND2_MOUSE ---SKSVEDPDQAT---TPTDVRDVDL Q4FK45_MOUSE Q4FK45_MOUSE ---SKSVEDPDQAT---TPTDVRDVDL CCND2_RAT CCND2_RAT ----KSVEDPDQAT---TPTDVRDVDL CCND2_HUMAN CCND2_HUMAN ----KSEDELDQAS---TPTDVRDIDL Q53ER2_HUMAN Q53ER2_HUMAN ----KSEDELDQAS---TPTDVRDIDL B2MVY2_SHEEP B2MVY2_SHEEP ----KSEDELDQAS---TPTDVRDIDL CCND2_BOVIN CCND2_BOVIN ----KSEDELDQAS---TPTDVRDIDL CCND2_PIG CCND2_PIG -----SEDELDQAS---TPTDVRDIDL A3KNN7_DANRE A3KNN7_DANRE GQRSKALDDQDQSS---TPTDVRDINL O57481_9PERO O57481_9PERO --------------------------- Q4SKE4_TETNG Q4SKE4_TETNG GPSGKGLDELDQSS---TPTDVRDVNL CCND2_CHICK CCND2_CHICK --PSKTIEELDQAS---TPTDVRDINL B7ZQ67_XENLA B7ZQ67_XENLA --SSKSVDELDQAS---TPTDVQDINL CCND2_XENLA CCND2_XENLA --SSKSVDELDQAS---TPTDVQDINL Q3KPK0_XENLA Q3KPK0_XENLA --SSKSVDELDQAS---TPTDVQDINL B5X4N6_SALSA B5X4N6_SALSA EQQDQSRTPTDVSS---TPTDVRDVNL Q4SAA8_TETNG Q4SAA8_TETNG QAGSKAREQQDQSS---TPTDVQDVNL MATCH CONSENSUS ?????????????????TPTDV?????


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