Alignment of the gene Family HBG050917 of HOVERGEN

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Isoforms are ON
A1L249_DANRE A1L249_DANRE -METNSKASAGREKECVCAPVRGCVLSDNVSLPSYSEYPAGRPF--INTPLSNT-HRTVK B8JJE8_MOUSE B8JJE8_MOUSE --------------------------MVRHSSSPYVLYPPDKPF--LNSDLRRSPNKPTF A0PJD7_MOUSE A0PJD7_MOUSE ----TRPPTRPQFSSVLAEPSRSNGNMVRHSSSPYVLYPPDKPF--LNSDLRRSPNKPTF B8JJE9_MOUSE B8JJE9_MOUSE ------------------------------------------------------------ B8JJE7_MOUSE B8JJE7_MOUSE AAASVSAASDSQFSSVLAEPSRSNGNMVRHSSSPYVLYPPDKPF--LNSDLRRSPNKPTF CEP57_MOUSE CEP57_MOUSE AAASVSAASDSQFSSVLAEPSRSNGNMVRHSSSPYVLYPPDKPF--LNSDLRRSPNKPTF B8JJF0_MOUSE B8JJF0_MOUSE ------------------------------------------------------------ B8JJF1_MOUSE B8JJF1_MOUSE ------------------------------------------------------------ CEP57_BOVIN CEP57_BOVIN AAASVSETSASQFSNILAEPSKSNGSMVRHSSSPYVVYPPDKPF--LNSDLRRSPNKPTF CEP57_HUMAN CEP57_HUMAN AAASVSAASGSHLSNSFAEPSRSNGSMVRHSSSPYVVYPSDKPF--LNSDLRRSPSKPTL Q4R704_MACFA Q4R704_MACFA --------------------------MVRHSSSPYVVYPSDKPF--LNSDLRRSPSKPTL Q4S6X3_TETNG Q4S6X3_TETNG ------------------------------------------------------------ Q5TZ43_DANRE Q5TZ43_DANRE -MDHFRDQSFNLDSPSKQSYVGSFYQPPEKMSRPLYMNPDTHPLNRKSSGLQDISPQLYQ Q6AXJ5_DANRE Q6AXJ5_DANRE ------------------------------MSRPLYMNPDTHPLNRKSSGLQDISPQLYQ MATCH CONSENSUS ????????????????????????????????????????????????????????????

A1L249_DANRE A1L249_DANRE AFPESSGAAIISALKNLQEKIRNLELERSDAQQKLQSISRESTH---------------- B8JJE8_MOUSE B8JJE8_MOUSE AYPESNSRAIFSALKNLQDKIRRLELERIQAEESVKTLSRETIEYKKVLDEQIQ------ A0PJD7_MOUSE A0PJD7_MOUSE AYPESNSRAIFSALKNLQDKIRRLELERIQAEESVKTLSRETIEYKKVLDEQIQ------ B8JJE9_MOUSE B8JJE9_MOUSE ----------------------------------------------------IQ------ B8JJE7_MOUSE B8JJE7_MOUSE AYPESNSRAIFSALKNLQDKIRRLELERIQAEESVKTLSRETIEYKKVLDEQIQ------ CEP57_MOUSE CEP57_MOUSE AYPESNSRAIFSALKNLQDKIRRLELERIQAEESVKTLSRETIEYKKVLDEQIQ------ B8JJF0_MOUSE B8JJF0_MOUSE ------------------------------------------------------------ B8JJF1_MOUSE B8JJF1_MOUSE ------------------------------------------------------------ CEP57_BOVIN CEP57_BOVIN AYPESNSRAIFSALKNLQDKIRRLELERIQAEESVKTLSKETIEYKKVLDEQIP------ CEP57_HUMAN CEP57_HUMAN AYPESNSRAIFSALKNLQDKIRRLELERIQAEESVKTLSRETIEYKKVLDEQIQ------ Q4R704_MACFA Q4R704_MACFA AYPESNSRAIFSALKNLQDKIRRLELERIQAEESVKTLSRETIEYKKVLDEQIQ------ Q4S6X3_TETNG Q4S6X3_TETNG --------AFVNALKNLQQKIDQMELEKKQAKAKNQQLSHRVTNHQPVSSPYVEAALPTA Q5TZ43_DANRE Q5TZ43_DANRE TVPDAGSRAVIAALKTLQEKMRRLELERVHAVKNVHHFSQPTRHQEDVSASKEQ------ Q6AXJ5_DANRE Q6AXJ5_DANRE TVPDAGSRAVIAALKTLQEKMRRLELERVHAVKNVQHFSQPTRHQEDVSASKEQ------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

A1L249_DANRE A1L249_DANRE -------SHTRDQHTRKNH------------------DVLSQLSAAEARCSRLEKQLNHM B8JJE8_MOUSE B8JJE8_MOUSE -----ERENSKNEESKHNQ------------------ELASQLVAAENKCNLLEKQLEYM A0PJD7_MOUSE A0PJD7_MOUSE -----ERENSKNEESKHNQ------------------ELASQLVAAENKCNLLEKQLEYM B8JJE9_MOUSE B8JJE9_MOUSE -----ERENSKNEESKHNQ------------------ELASQLVAAENKCNLLEKQLEYM B8JJE7_MOUSE B8JJE7_MOUSE -----ERENSKNEESKHNQ------------------ELASQLVAAENKCNLLEKQLEYM CEP57_MOUSE CEP57_MOUSE -----ERENSKNEESKHNQ------------------ELASQLVAAENKCNLLEKQLEYM B8JJF0_MOUSE B8JJF0_MOUSE -----------------------------------------------------------M B8JJF1_MOUSE B8JJF1_MOUSE -----------------------------------------------------------M CEP57_BOVIN CEP57_BOVIN -----ERENSKNEESKHNQ------------------ELTSQLLAAENKCNLLEKQLEYM CEP57_HUMAN CEP57_HUMAN -----ERENSKNEESKHNQ------------------ELTSQLLAAENKCNLLEKQLEYM Q4R704_MACFA Q4R704_MACFA -----ERENSKNEESKHNQ------------------ELTSQLLAAENKCNLLEKQLEYM Q4S6X3_TETNG Q4S6X3_TETNG GQPGPDGWNQEGEGGSGRQASAVSDQIWCLNGLFMLAEYTLKLQSVEAQCKILEKQFNYM Q5TZ43_DANRE Q5TZ43_DANRE ------EHNMRDNDSTQRK------------------VLVSKLHSAETRCSLLEKQLNYM Q6AXJ5_DANRE Q6AXJ5_DANRE ------EHNMRDNDLTQRK------------------VLVSKLHSAETRCSLLEKQLNFM MATCH * CONSENSUS ??????????????????????????????????????????L???E??C??LEKQ???M

A1L249_DANRE A1L249_DANRE RSAVRNTQSDRTAVLRQQVSLERLGSVHQADVH---HKLAVLEQEHHRLTETQSCAERKI B8JJE8_MOUSE B8JJE8_MOUSE RNMIKHAEMERTSVLEKQVSLERERQHDQTHVQSQLEKLDLLEQEYNKLTAMQALAEKKM A0PJD7_MOUSE A0PJD7_MOUSE RNMIKHAEMERTSVLEKQVSLERERQHDQTHVQSQLEKLDLLEQEYNKLTAMQALAEKKM B8JJE9_MOUSE B8JJE9_MOUSE RNMIKHAEMERTSVLEKQVSLERERQHDQTHVQSQLEKLDLLEQEYNKLTAMQALAEKKM B8JJE7_MOUSE B8JJE7_MOUSE RNMIKHAEMERTSVLEKQVSLERERQHDQTHVQSQLEKLDLLEQEYNKLTAMQALAEKKM CEP57_MOUSE CEP57_MOUSE RNMIKHAEMERTSVLEKQVSLERERQHDQTHVQSQLEKLDLLEQEYNKLTAMQALAEKKM B8JJF0_MOUSE B8JJF0_MOUSE RNMIKHAEMERTSVLEKQVSLERERQHDQTHVQSQLEKLDLLEQEYNKLTAMQALAEKKM B8JJF1_MOUSE B8JJF1_MOUSE RNMIKHAEMERTSVLEKQVSLERERQHDQTHVQSQLEKLDLLEQEYNKLTAMQALAEKKM CEP57_BOVIN CEP57_BOVIN RNMIKHAEMERTSVLEKQVSLERERQHDQTHVQNQLEKLDLLEQEYNKLTTMQALAEKKM CEP57_HUMAN CEP57_HUMAN RNMIKHAEMERTSVLEKQVSLERERQHDQTHVQSQLEKLDLLEQEYNKLTTMQALAEKKM Q4R704_MACFA Q4R704_MACFA RNMIKHAEMERTSVLEKQVSLERERQHDLTHVQSQLEKLDLLEQEYNKLTTMQALAEKKM Q4S6X3_TETNG Q4S6X3_TETNG RKMVEIGNKERKAVAEKQVL--QESANQNSDVKSQGKKLERLEIEYSKLSRTQALADTKL Q5TZ43_DANRE Q5TZ43_DANRE KRMVECAEKDTVTHTDRKDSLPTEHTHADPQIQAQLNKLERLEKEYLRLTNTQSVAERKI Q6AXJ5_DANRE Q6AXJ5_DANRE KRMVECAEKDTITHTDRKDSLPTEHTHADPQIQAQLNKLERLEKEYLRLTNTQSVAERKI MATCH : :. : : : :: ..:: .** ** *: :*: *: *: *: CONSENSUS R?M???AE??R??V???QVSL??E??H????VQ?QL?KL??LE?EY??LT??Q??AE?K?

A1L249_DANRE A1L249_DANRE QQLERKLQEEEQQRRRMQDTAAQLQTGLEANRLLIQSVSPRPHKSSKIKQKKISSKKTHS B8JJE8_MOUSE B8JJE8_MOUSE QELESKLREEEQERKRMQARAAELQSGLEANRLIFEDKTTSCVSTSTRKIKKKKSKPPEK A0PJD7_MOUSE A0PJD7_MOUSE QELESKLREEEQERKRMQARAAELQSGLEANRLIFEDKTTSCVSTSTRKIKKKKSKPPEK B8JJE9_MOUSE B8JJE9_MOUSE QELESKLREEEQERKRMQARAAE--SGLEANRLIFEDKTTSCVSTSTRKIKKKKSKPPEK B8JJE7_MOUSE B8JJE7_MOUSE QELESKLREEEQERKRMQARAAELQSGLEANRLIFEDKTTSCVSTSTRKIKKKKSKPPEK CEP57_MOUSE CEP57_MOUSE QELESKLREEEQERKRMQARAAELQSGLEANRLIFEDKTTSCVSTSTRKIKKKKSKPPEK B8JJF0_MOUSE B8JJF0_MOUSE QELESKLREEEQERKRMQARAAELQSGLEANRLIFEDKTTSCVSTSTRKIKKKKSKPPEK B8JJF1_MOUSE B8JJF1_MOUSE QELESKLREEEQERKRMQARAAELQSGLEANRLIFEDKTTSCVSTSTRKIKKKKSKPPEK CEP57_BOVIN CEP57_BOVIN QELEAKLRQEEQERKRMQAKAAQLQTGLEVNRLIYEDKATSCV-PNTKRIKKKKSKPPEK CEP57_HUMAN CEP57_HUMAN QELEAKLHEEEQERKRMQAKAAELQTGLETNRLIFEDKATPCV-PNARRIKKKKSKPPEK Q4R704_MACFA Q4R704_MACFA QELEAKLHEEEQERKRMQAKAAELQTGLETNRLTFEDKATPRV-PSARRIKKKKSKPPEK Q4S6X3_TETNG Q4S6X3_TETNG AILEEKLQKETCQRLLVQEKAERLQRELDTSLRS-----PAWVKTEEKKTQTPRTAKNPP Q5TZ43_DANRE Q5TZ43_DANRE ELLEQKLLEEEHERKLVQEKAEELQRELENNILSL----SAATQPKGKKKRRDKASCKKS Q6AXJ5_DANRE Q6AXJ5_DANRE ELLEQKLLEEEHERKLVQEKAEELQRELENNILSL----SAATQPKGKKKRRDKASCKKS MATCH ** ** :* :* :* * . *: . . .. : : : CONSENSUS ??LE?KL?EEE?ERK??Q??A??LQ??LE?N?L????????????????????K??????

A1L249_DANRE A1L249_DANRE P--------QPHYRLSLGDVPFVTGTSTVSSHSVRANVQHVLHLMKQHQPQLCNE-QVLG B8JJE8_MOUSE B8JJE8_MOUSE KGSRTYFGAQPHYRLCLGDMPFVAGTSTSPSHAVVANVQHVLHLMKHHSKALCND-RVVN A0PJD7_MOUSE A0PJD7_MOUSE KGSRTYFGAQPHYRLCLGDMPFVAGTSTSPSHAVVANVQHVLHLMKHHSKALCND-RVVN B8JJE9_MOUSE B8JJE9_MOUSE KGSRTYFGAQPHYRLCLGDMPFVAGTSTSPSHAVVANVQHVLHLMKHHSKALCND-RVVN B8JJE7_MOUSE B8JJE7_MOUSE --------------------------STSPSHAVVANVQHVLHLMKHHSKALCND-RVVN CEP57_MOUSE CEP57_MOUSE KGSRTYFGAQPHYRLCLGDMPFVAGTSTSPSHAVVANVQHVLHLMKHHSKALCND-RVVN B8JJF0_MOUSE B8JJF0_MOUSE KGSRTYFGAQPHYRLCLGDMPFVAGTSTSPSHAVVANVQHVLHLMKHHSKALCND-RVVN B8JJF1_MOUSE B8JJF1_MOUSE KGSRTYFGAQPHYRLCLGDMPFVAGTSTSPSHAVVANVQHVLHLMKHHSKALCND-RVVN CEP57_BOVIN CEP57_BOVIN KGSRNYFAVQPHYRLCLGDMPFVAGKSTSPSHAVVANVQHVLHLMKQHSKVLCND-RVVS CEP57_HUMAN CEP57_HUMAN KSSRNYFGAQPHYRLCLGDMPFVAGKSTSPSHAVVANVQLVLHLMKQHSKALCND-RVIN Q4R704_MACFA Q4R704_MACFA KSSRNYFGAQPHYRLCLGDMPFVAGKSTSPSHAVVANVQLVLHLMKQHSKALCND-RVIN Q4S6X3_TETNG Q4S6X3_TETNG QQCQVVLLGQLKNK----KMPFVAGKSTSPSHSVHANVQSVLHMMKHHQPWLCEQVSALH Q5TZ43_DANRE Q5TZ43_DANRE PTAKVEAVSAPKSK----RLPFVAGTSTSPSHSVNANVQSVLHMMKHRNPRLCERVSALQ Q6AXJ5_DANRE Q6AXJ5_DANRE PSAKVEAVSAPKSK----RLPFVAGTSTSPSHSVNANVQSVLHMMKHRNPRLCERVSALQ MATCH ** .**:* **** ***:**::. **: .: CONSENSUS ??????????P?????????PFVAG?STSPSH?V?ANVQ?VLH?MK?H???LC???????

A1L249_DANRE A1L249_DANRE G------GCTSASSSSTSS-----SCSCSEDLSELLLTLQDELGHMSFEQQDLSRQLQSC B8JJE8_MOUSE B8JJE8_MOUSE SVPLAKQACSRVSKSKKSVVPP--SSSVNEELSDVLQTLQDEFGQMSFDHQQLTKLIQES A0PJD7_MOUSE A0PJD7_MOUSE SVPLAKQACSRVSKSKKSVVPP--SSSVNEELSDVLQTLQDEFGQMSFDHQQLTKLIQES B8JJE9_MOUSE B8JJE9_MOUSE SVPLAKQACSRVSK---------------------------------------------- B8JJE7_MOUSE B8JJE7_MOUSE SVPLAKQACSRVSKSKKSVVPP--SSSVNEELSDVLQTLQDEFGQMSFDHQQLTKLIQES CEP57_MOUSE CEP57_MOUSE SVPLAKQACSRVSKSKKSVVPP--SSSVNEELSDVLQTLQDEFGQMSFDHQQLTKLIQES B8JJF0_MOUSE B8JJF0_MOUSE SVPLAKQACSRVSKSKKSVVPP--SSSVNEELSDVLQTLQDEFGQMSFDHQQLTKLIQES B8JJF1_MOUSE B8JJF1_MOUSE SVPLAKQACSRVSKSKKSVVPP--SSSVNEELSDVLQTLQDEFGQMSFDHQQLTKLIQES CEP57_BOVIN CEP57_BOVIN SIPLAKQVSSRTGKSKKSATPPS-SSSVNEELSEVLQTLQDEFGQMSFDHQQLAKLIQES CEP57_HUMAN CEP57_HUMAN SIPLAKQVSSRGGKSKKLSVTPPSSNGINEELSEVLQTLQDEFGQMSFDHQQLAKLIQES Q4R704_MACFA Q4R704_MACFA SIPLAKQVSSRGGKSKKLSVTSP-SNGINEELAEVLQTLQDEFGQMSFDHQQLAKLIQES Q4S6X3_TETNG Q4S6X3_TETNG APAGAIRRNLSGEFSSKPARKPQAGDQSLDSLSDLLLALQDELGQMSFEHQDLLRQLGVV Q5TZ43_DANRE Q5TZ43_DANRE KSSSEKQRTHH-----RPPSSPSRSASTLGSLSELLLALQDELGQMSFEHQELVKQIDET Q6AXJ5_DANRE Q6AXJ5_DANRE KSSSEKQRTHH-----RPPSSPSRSASTLGSLSELLLALQDELGQMSFEHQELVKQIDET MATCH CONSENSUS ?????KQ?????????????????S??????LS??L??LQDE?GQMSF?HQ?L???????

A1L249_DANRE A1L249_DANRE SSV-LRQDLELQMENLLKRMENKAEQISKLRRCQTQCCKQ-------------------- B8JJE8_MOUSE B8JJE8_MOUSE PTVELKDNLECELEALVGRMEAKANQITKVRKYQAQLEKQNIDKQKKELKANKKTLDEEG A0PJD7_MOUSE A0PJD7_MOUSE PTVELKDNLECELEALVGRMEAKANQITKVRKYQAQLEKQNIDWQKKKKK---------- B8JJE9_MOUSE B8JJE9_MOUSE ------------------------------------------------------------ B8JJE7_MOUSE B8JJE7_MOUSE PTVELKDNLECELEALVGRMEAKANQITKVRKYQAQLEKQNIDKQKKELKANKKTLDEEG CEP57_MOUSE CEP57_MOUSE PTVELKDNLECELEALVGRMEAKANQITKVRKYQAQLEKQNIDKQKKELKANKKTLDEEG B8JJF0_MOUSE B8JJF0_MOUSE PTVELKDNLECELEALVGRMEAKANQITKVRKYQAQLEKQNIDK---------------- B8JJF1_MOUSE B8JJF1_MOUSE PTVELKDNLECELEALVGRMEAKANQITKVRKYQAQLEKQNIDKQKKELKANKKTLDEEG CEP57_BOVIN CEP57_BOVIN PTVELKDNLECELEALVGRMEAKANQITKVRKYQAQLEKQKLEKQKKELKATRKTLDEEG CEP57_HUMAN CEP57_HUMAN PTVELKDKLECELEALVGRMEAKANQITKVRKYQAQLEKQKLEKQKKELKATKKTLDEER Q4R704_MACFA Q4R704_MACFA PTVELKDKLECELEALVGRMEAKANQITKVRKYQAQLEKQKLEKQKKELKATKKTLDEEG Q4S6X3_TETNG Q4S6X3_TETNG QNREEKEDLKLELESLVSRMEEKGAQITKLRKH--------------------------- Q5TZ43_DANRE Q5TZ43_DANRE SRRELRDDLERELDCLVKRMEEKAAQISKLRKHQQTVQKLSQPSCSPRQKQQRPQWTTSV Q6AXJ5_DANRE Q6AXJ5_DANRE SRRELRDDLERELDCLVKRMEEKAAQISKLRKHQQTVQKLSQPSCSPRQKQQRPQWTTSV MATCH CONSENSUS ???EL???LE?EL??LV?RME?KA?QI?K?RK?Q????K?????????????????????

A1L249_DANRE A1L249_DANRE -SRAVCSGG-----SGGSAAVMTLKHKPGDRSRDSLRLLKDLRSLQNTLRSDHTL--- B8JJE8_MOUSE B8JJE8_MOUSE NSSGRSSGV-----PRTASKKDLAKQRPGEKSRKNLQLLKDMQTIQNSLQSSNLCWDY A0PJD7_MOUSE A0PJD7_MOUSE ---------------------------------------------------------- B8JJE9_MOUSE B8JJE9_MOUSE ---------------------------------------------------------- B8JJE7_MOUSE B8JJE7_MOUSE NSSGRSSGV-----PRTASKKDLAKQRPGEKSRKNLQLLKDMQTIQNSLQSSNLCWDY CEP57_MOUSE CEP57_MOUSE NSSGRSSGV-----PRTASKKDLAKQRPGEKSRKNLQLLKDMQTIQNSLQSSNLCWDY B8JJF0_MOUSE B8JJF0_MOUSE ---------------------------------------------------------- B8JJF1_MOUSE B8JJF1_MOUSE NSSGRSSGV-----PRTASKKDLAKQRPGEKSRKNLQLLKDMQTIQNSLQSSNLCWDY CEP57_BOVIN CEP57_BOVIN NSSSRSTT------TGTTNKKDFAKPRPGEKSRKNLQLLKDMQSIQNSLQSNSLCWDY CEP57_HUMAN CEP57_HUMAN NSSSRSGI------TGTTNKKDFMKLRPGEKRRKNLQLLKDMQSIQNSLQSSSLCWDY Q4R704_MACFA Q4R704_MACFA NSSSRSGI------TGTTNKKDFTKLRPGEKGRKNLQLLKDMQTIQNSLQSRSLCWDY Q4S6X3_TETNG Q4S6X3_TETNG ---------------------------------------------------------- Q5TZ43_DANRE Q5TZ43_DANRE DNKSRAESGVQPLPPSPVKASSSTGTKQSRSGQGSLKLLKETQKLCSSLRRQDIKWET Q6AXJ5_DANRE Q6AXJ5_DANRE DNKSRAESGVQPLPPSPVKASSSTGTKQSRSGQGSLKLLKETQKLCSSLRRQDIKWET MATCH CONSENSUS ??????????????????????????????????????????????????????????


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