Alignment of the gene Family HBG050984 of HOVERGEN

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Threshold: 50% 80% 100%
Size: Bigger Smaller Normal
Isoforms are ON
Q869D8_ASCSS Q869D8_ASCSS -----------------------------------------MPALDVTKRNLSFNSLGKD Q4SXZ6_TETNG Q4SXZ6_TETNG ------------------------------------------------------------ Q9PUI5_OREMO Q9PUI5_OREMO SNFWTSLRGKHAADRERGSKGMENPGYCSGSFDGLHHPSDDDDDEMVDIAGATLDFSSTD CLCN5_CAVPO CLCN5_CAVPO ------------------------------------------------------------ CLCN5_PIG CLCN5_PIG ------------------------------------------------------------ CLCN5_RABIT CLCN5_RABIT ------------------------------------------------------------ CLCN5_RAT CLCN5_RAT ------------------------------------------------------------ Q8CI67_MOUSE Q8CI67_MOUSE ------------------------------------------------------------ Q3UL16_MOUSE Q3UL16_MOUSE ------------------------------------------------------------ B1ATV0_MOUSE B1ATV0_MOUSE ----------------MAMWQGAMDNRGFHQGSFSSFQSSSSDEDLMDIPGTAMDFSMRD CLCN5_MOUSE CLCN5_MOUSE ------------------------------------------------------------ Q8C6W8_MOUSE Q8C6W8_MOUSE ------------------------------------------------------------ B3KRR2_HUMAN B3KRR2_HUMAN ------------------------------------------------------------ B3KPN6_HUMAN B3KPN6_HUMAN ----------------MAMWQGAMDNRGFQQGSFSSFQNSSSDEDLMDIPATAMDFSMRD A8K4H5_HUMAN A8K4H5_HUMAN ------------------------------------------------------------ CLCN5_HUMAN CLCN5_HUMAN ------------------------------------------------------------ CLCN5_PONAB CLCN5_PONAB ------------------------------------------------------------ Q28C29_XENTR Q28C29_XENTR -----------------------MDNKGFRRSSLTSFHSSTSDEDMVEINEATLDFTMTD O13080_XENLA O13080_XENLA -----------------------MDNKGFRRSSLASFHSNTSDEDMVEITEATLDFTMTD A2BD91_XENLA A2BD91_XENLA ------------------------------------------------------------ Q9PWK7_XENLA Q9PWK7_XENLA -----------------------MDNKGFRRSSLASFHSNTSDEDMVEITEATLDFTMTD Q4LAL8_CANFA Q4LAL8_CANFA ------------------------------------MDAASDPYLPYDGGG--------- Q4LAL7_CANFA Q4LAL7_CANFA ------------------------------------MDAASDPYLPYDGGG--------- Q4R6L2_MACFA Q4R6L2_MACFA -----------------MESEQLFHRGYYRNSYNSITSASSDEEL-LDGAGVIMDFQTSE B7Z932_HUMAN B7Z932_HUMAN -----------------MESEQLFHRGYYRNSYNSITSASSDEEL-LDGAGVIMDFQTSE CLCN3_PONAB CLCN3_PONAB -----------------MESEQLFHRGYYRNSYNSITSASSDEEL-LDGAGVIMDFQTSE B3KXK0_HUMAN B3KXK0_HUMAN ------------------------------------MDASSDPYLPYDGGG--------- B9EGJ9_HUMAN B9EGJ9_HUMAN -----------------------------------MVTLQLGESHYVVQAGLQLLGSSNP Q8K4W9_MOUSE Q8K4W9_MOUSE ------------------------------------MDASSDPYLPYDGGG--------- Q8K4W7_MOUSE Q8K4W7_MOUSE ------------------------------------------------------------ P97274_CAVPO P97274_CAVPO ------------------------------------------------------------ CLCN3_CAVPO CLCN3_CAVPO ------------------------------------------------------------ Q6PEV2_MOUSE Q6PEV2_MOUSE ------------------------------------------------------------ CLCN3_MOUSE CLCN3_MOUSE -----------------MESEQLFHRGYYRNSYNSITSASSDEEL-LDGAGAIMDFQTSE Q3TTK0_MOUSE Q3TTK0_MOUSE -----------------MESEQLFHRGYYRNSYNSITSASSDEEL-LDGAGAIMDFQTSE CLCN3_RAT CLCN3_RAT -----------------MESEQLFHRGYYRNSYNSITSASSDEEL-LDGAGAIMDFQTSE Q8K4X1_MOUSE Q8K4X1_MOUSE -----------------MESEQLFHRGYYRNSYNSITSASSDEEL-LDGAGAIMDFQTSE Q3TF45_MOUSE Q3TF45_MOUSE -----------------MESEQLFHRGYYRNSYNSITSASSDEEL-LDGAGAIMDFQTSE Q3UEX5_MOUSE Q3UEX5_MOUSE -----------------MESEQLFHRGYYRNSYNSITSASSDEEL-LDGAGAIMDFQTSE Q790S0_MOUSE Q790S0_MOUSE ------------------------------------------------------------ Q6PGA5_MOUSE Q6PGA5_MOUSE ------------------------------------MDASSDPYLPYDGGG--------- Q8K4W8_MOUSE Q8K4W8_MOUSE ------------------------------------MDASSDPYLPYDGGG--------- B4F6X6_XENTR B4F6X6_XENTR -----------------MESEQLFQRSYYRNSYNSITSASSDEEL-LDGAGGMMDFHTLE A5PKR3_XENLA A5PKR3_XENLA ------------------------------------MDISSDPYLPYDGGG--------- Q9YH11_XENLA Q9YH11_XENLA ------------------------------------MDISSDPYLPYDGGG--------- A0PJS1_DANRE A0PJS1_DANRE -----------------------------------MEEESADPYLPYDGGGG-------- A1A5X0_DANRE A1A5X0_DANRE -----------------MESEQLFNRGYGRNSYNSITSASSDEEL-LDGAGVIMDFHTTE Q4T7N7_TETNG Q4T7N7_TETNG ---------------------------------MDEEDAAADPYLPYDGGG--------- Q9PUI6_OREMO Q9PUI6_OREMO ------------------------------------------------------------ Q08BG8_DANRE Q08BG8_DANRE ------------------------------------------------------------ Q4SER7_TETNG Q4SER7_TETNG ------------------------------------------------------------ B0BMM3_XENTR B0BMM3_XENTR ------------------------------------------------------------ Q4F894_BOVIN Q4F894_BOVIN ------------------------------------------------------------ B7Z5Z4_HUMAN B7Z5Z4_HUMAN ------------------------------------------------------------ Q4G0X3_HUMAN Q4G0X3_HUMAN ------------------------------------------------------------ A1L3U1_HUMAN A1L3U1_HUMAN ------------------------------------------------------------ CLCN4_HUMAN CLCN4_HUMAN ------------------------------------------------------------ CLCN4_RAT CLCN4_RAT ------------------------------------------------------------ Q56A19_RAT Q56A19_RAT ------------------------------------------------------------ CLCN4_MOUSE CLCN4_MOUSE ------------------------------------------------------------ Q3LRV6_MOUSE Q3LRV6_MOUSE ------------------------------------------------------------ Q8CBL5_MOUSE Q8CBL5_MOUSE ------------------------------------------------------------ Q99JZ2_MOUSE Q99JZ2_MOUSE ------------------------------------------------------------ Q2TAX6_MOUSE Q2TAX6_MOUSE ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

Q869D8_ASCSS Q869D8_ASCSS QSFPLRVWTQTSVPNQQNT------QQDDAKKCCE--EEEFDEVGRYQDFHTIDWLREIC Q4SXZ6_TETNG Q4SXZ6_TETNG --------------------------GNGPSNLMDPLEDPVPGLGTYEDFNTIDWVREKS Q9PUI5_OREMO Q9PUI5_OREMO DVPPLSSGVYEEHNGTSRT---AGMNGSGPSRLVDPLEDPLPGVGTYEDFNTIDWVRENS CLCN5_CAVPO CLCN5_CAVPO ---------------------------------MDFLEEPIPGVGTYDDFNTIDWVREKS CLCN5_PIG CLCN5_PIG ---------------------------------MDFLEEPIPGVGTYDDFNTIDWVREKS CLCN5_RABIT CLCN5_RABIT ---------------------------------MDFLEEPIPGVGTYDDFNTIDWVREKS CLCN5_RAT CLCN5_RAT ---------------------------------MDFLEEPIPGVGTYDDFNTIDWVREKS Q8CI67_MOUSE Q8CI67_MOUSE ---------------------------------MDFLEEPIPGVGTYDDFNTIDWVREKS Q3UL16_MOUSE Q3UL16_MOUSE ---------------------------------MDFLEEPIPGVGTYDDFNTIDWVREKS B1ATV0_MOUSE B1ATV0_MOUSE DVPPLDREIEGNKSYN-------GGGIGSSNRVMDFLEEPIPGVGTYDDFNTIDWVREKS CLCN5_MOUSE CLCN5_MOUSE ---------------------------------MDFLEEPIPGVGTYDDFNTIDWVREKS Q8C6W8_MOUSE Q8C6W8_MOUSE ---------------------------------MDFLEEPIPGVGTYDDFNTIDWVREKS B3KRR2_HUMAN B3KRR2_HUMAN ------------------------------------------------------------ B3KPN6_HUMAN B3KPN6_HUMAN DVPPLDREVGEDKSYN-------GGGIGSSNRIMDFLEEPIPGVGTYDDFNTIDWVREKS A8K4H5_HUMAN A8K4H5_HUMAN ---------------------------------MDFLEEPIPGVGTYDDFNTIDWVREKS CLCN5_HUMAN CLCN5_HUMAN ---------------------------------MDFLEEPIPGVGTYDDFNTIDWVREKS CLCN5_PONAB CLCN5_PONAB ---------------------------------MDFLEEPIPGVGTYDDFNTIDWVREKS Q28C29_XENTR Q28C29_XENTR DVPPIDRDMAGGFVSYN------GNGLHGPSKVMDFLD--VPGVGTYEDFNTIDWVREKS O13080_XENLA O13080_XENLA DVPPIDRDMAAGFVSYN------GNGLNGGAKVMDFLD--VPGVGTYEDFNTIDWVREKS A2BD91_XENLA A2BD91_XENLA ---------AGSKGFVSYN----GNGLNGGAKVMDFLD--VPGVGTYEDFNTIDWVREKS Q9PWK7_XENLA Q9PWK7_XENLA DVPPIDRDMAAGFVSYN------GNGLNGGAKVMDFLD--VPGVGTYEDFNTIDWVREKS Q4LAL8_CANFA Q4LAL8_CANFA DCIPLRELHKRGTHYTMTN----GGSINSSTHLLDLLDEPIPGVGTYDDFHTIDWVREKC Q4LAL7_CANFA Q4LAL7_CANFA DCIPLRELHKRGTHYTMTN----GGSINSSTHLLDLLDEPIPGVGTYDDFHTIDWVREKC Q4R6L2_MACFA Q4R6L2_MACFA DDNLLDGDTAVGTHYTMTN----GGSINSSTHLLDLLDEPIPGVGTYDDFHTIDWVREKC B7Z932_HUMAN B7Z932_HUMAN DDNLLDGDTAVGTHYTMTN----GGSINSSTHLLDLLDEPIPGVGTYDDFHTIDWVREKC CLCN3_PONAB CLCN3_PONAB DDNLLDGDTAVGTHYTMTN----GGSINSSTHLLDLLDEPIPGVGTYDDFHTIDWVREKC B3KXK0_HUMAN B3KXK0_HUMAN DNIPLRELHKRGTHYTMTN----GGSINSSTHLLDLLDEPIPGVGTYDDFHTIDWVREKC B9EGJ9_HUMAN B9EGJ9_HUMAN PALASQVAEITGTHYTMTN----GGSINSSTHLLDLLDEPIPGVGTYDDFHTIDWVREKC Q8K4W9_MOUSE Q8K4W9_MOUSE DSIPLRELHKRGTHYTMTN----GGSINSSTHLLDLLDEPIPGVGTYDDFHTIDWVREKC Q8K4W7_MOUSE Q8K4W7_MOUSE ----------------MTN----GGSINSSTHLLDLLDEPIPGVGTYDDFHTIDWVREKC P97274_CAVPO P97274_CAVPO ----------------MTN----GGSINSSTHLLDLLDEPIPGVGTYDDFHTIDWVREKC CLCN3_CAVPO CLCN3_CAVPO ----------------MTN----GGSINSSTHLLDLLDEPIPGVGTYDDFHTIDWVREKC Q6PEV2_MOUSE Q6PEV2_MOUSE ----------------MTN----GGSINSSTHLLDLLDEPIPGVGTYDDFHTIDWVREKC CLCN3_MOUSE CLCN3_MOUSE DDNLLDGDTAAGTHYTMTN----GGSINSSTHLLDLLDEPIPGVGTYDDFHTIDWVREKC Q3TTK0_MOUSE Q3TTK0_MOUSE DDNLLDGDTAAGTHYTMTN----GGSINSSTHLLDLLDEPIPGVGTYDDFHTIDWVREKC CLCN3_RAT CLCN3_RAT DDNLLDGDTAAGTHYTMTN----GGSINSSTHLLDLLDEPIPGVGTYDDFHTIDWVREKC Q8K4X1_MOUSE Q8K4X1_MOUSE DDNLLDGDTAAGTHYTMTN----GGSINSSTHLLDLLDEPIPGVGTYDDFHTIDWVREKC Q3TF45_MOUSE Q3TF45_MOUSE DDNLLDGDTAAGTHYTMTN----GGSINSSTHLLDLLDEPIPGVGTYDDFHTIDWVREKC Q3UEX5_MOUSE Q3UEX5_MOUSE DDNLLDGDTAAGTHYTMTN----GGSINSSTHLLDLLDEPIPGVGTYDDFHTIDWVREKC Q790S0_MOUSE Q790S0_MOUSE ----------------MTN----GGSINSSTHLLDLLDEPIPGVGTYDDFHTIDWVREKC Q6PGA5_MOUSE Q6PGA5_MOUSE DSIPLRELHKRGTHYTMTN----GGSINSSTHLLDLLDEPIPGVGTYDDFHTIDWVREKC Q8K4W8_MOUSE Q8K4W8_MOUSE DSIPLRELHKRGTHYTMTN----GGSINSSTHLLDLLDEPIPGVGTYDDFHTIDWVREKC B4F6X6_XENTR B4F6X6_XENTR DDNLLDGDASVGTHYTMTN----GGAINSTTHLLDLLDEPIPGVGTYDDFHTIDWVREKC A5PKR3_XENLA A5PKR3_XENLA DNIPLRDLHKRGTHYTVTN----GGAINSTTHLLDLLDEPIPGVGTYDDFHTIDWVREKC Q9YH11_XENLA Q9YH11_XENLA DNIPLRDLHKRGTHYTVTN----GGAINSTTHLLDLLDEPIPGVGTYDDFHTIDWVREKC A0PJS1_DANRE A0PJS1_DANRE DTIPLQELSGRGSNYAMSNGGGGGGGASSSTHLLDLLEEPIPGVGTYDDFHTIDWVREKC A1A5X0_DANRE A1A5X0_DANRE DDNLLDGDASPGSNYAMSNGGGGGGGASSSTHLLDLLEEPIPGVGTYDDFHTIDWVREKC Q4T7N7_TETNG Q4T7N7_TETNG DTIPLQEIPKRGSNYNMSN---GGGAPSSSTHLLDFLEEPIPGVGTYDDFHTIDWVREKC Q9PUI6_OREMO Q9PUI6_OREMO ----------------MSN---GGGAPSSSTHLLDFLEEPIPGVGTYDDFHTIDWVREKC Q08BG8_DANRE Q08BG8_DANRE -------MAEAEGISSATP----TEEMNGAGNLMDFLDEPFPDVGTYEDFHTIDWLREKS Q4SER7_TETNG Q4SER7_TETNG --------------------------MNGAGNLMDFLDEPFPDVGTYEDFHTIDWLREKS B0BMM3_XENTR B0BMM3_XENTR ----------------MVN----TGDINGSSNLMDFLDEPIPDVGTYEDFHTIDWLREKS Q4F894_BOVIN Q4F894_BOVIN ----------------MVN----TGVISGSGNLMDFLDEPFPDVGTYEDFHTIDWLREKS B7Z5Z4_HUMAN B7Z5Z4_HUMAN ------------------------------------------------------------ Q4G0X3_HUMAN Q4G0X3_HUMAN ----------------MVN----AGAMSGSGNLMDFLDEPFPDVGTYEDFHTIDWLREKS A1L3U1_HUMAN A1L3U1_HUMAN ----------------MVN----AGAMSGSGNLMDFLDEPFPDVGTYEDFHTIDWLREKS CLCN4_HUMAN CLCN4_HUMAN ----------------MVN----AGAMSGSGNLMDFLDEPFPDVGTYEDFHTIDWLREKS CLCN4_RAT CLCN4_RAT ---------------------------------MDFLDEPFPDVGTYEDFHTIDWLREKS Q56A19_RAT Q56A19_RAT --------------------------MSASGNLMDFLDEPFPDVGTYEDFHTIDWLREKS CLCN4_MOUSE CLCN4_MOUSE ---------------------------------MDFLEEPFPDVGTYEDFHTIDWLREKS Q3LRV6_MOUSE Q3LRV6_MOUSE ------------------------------------------------------------ Q8CBL5_MOUSE Q8CBL5_MOUSE ---------------------------------MDFLEEPFPDVGTYEDFHTIDWLREKS Q99JZ2_MOUSE Q99JZ2_MOUSE ---------------------------------MDFLEEPFPDVGTYEDFHTIDWLREKS Q2TAX6_MOUSE Q2TAX6_MOUSE ---------------------------------MDFLEEPFPDVGTYEDFHTIDWLREKS MATCH CONSENSUS ??????????????????????????????????D?L?EP?P?VGTY?DF?TIDW?REK?

Q869D8_ASCSS Q869D8_ASCSS RNKLRHRQ----------------------IYLRKFDSCFNRIRAFHDAISAWLLVLLIG Q4SXZ6_TETNG Q4SXZ6_TETNG KDRDRHRE----------------------ITKNSRRSTAALLHSVSDAFSGWLLMLLVG Q9PUI5_OREMO Q9PUI5_OREMO KDRDRHRE----------------------ITNKSRQSTVALLHSISDAFSGWLLMLLVG CLCN5_CAVPO CLCN5_CAVPO RDRDRHRE----------------------ITNRSKESTWALIHSVSDAFSGWLLMLLIG CLCN5_PIG CLCN5_PIG RDRDRHRE----------------------ITNKSKESTWALIHSVSDAFSGWLLMLLIG CLCN5_RABIT CLCN5_RABIT RDRDRHRE----------------------ITNKSKESTWALIHSVSDAFSGWLLMLLIG CLCN5_RAT CLCN5_RAT RDRDRHRE----------------------ITNKSKESTWALIHSVSDAFSGWLLMLLIG Q8CI67_MOUSE Q8CI67_MOUSE RDRDRHRE----------------------ITNKSKESTWALIHSVSDAFSGWLLMLLIG Q3UL16_MOUSE Q3UL16_MOUSE RDRDRHRE----------------------ITNKSKESTWALIHGVSDAFSGWLLMLLIG B1ATV0_MOUSE B1ATV0_MOUSE RDRDRHRE----------------------ITNKSKESTWALIHSVSDAFSGWLLMLLIG CLCN5_MOUSE CLCN5_MOUSE RDRDRHRE----------------------ITNKSKESTWALIHSVSDAFSGWLLMLLIG Q8C6W8_MOUSE Q8C6W8_MOUSE RDRDRHRE----------------------ITNKSKESTWALIHSVSDAFSGWLLMLLIG B3KRR2_HUMAN B3KRR2_HUMAN ----------------------------------------------------------MN B3KPN6_HUMAN B3KPN6_HUMAN RDRDRHRE----------------------ITNKSKESTWALIHSVSDAFSGWLLMLLIG A8K4H5_HUMAN A8K4H5_HUMAN RDRDRHRE----------------------ITNKSKESTWALIHSVSDAFSGWLLMLLIG CLCN5_HUMAN CLCN5_HUMAN RDRDRHRE----------------------ITNKSKESTWALIHSVSDAFSGWLLMLLIG CLCN5_PONAB CLCN5_PONAB RDRDRHRE----------------------ITNKSKESTWALIHSVSDAFSGWLLMLLIG Q28C29_XENTR Q28C29_XENTR RDRDRHRE----------------------ILSKSKESTWALLRSISDAFSGWMLMLLIG O13080_XENLA O13080_XENLA RDRDRHRE----------------------ILSRSKESTWALLHSVSDAFSGWMLMLLIG A2BD91_XENLA A2BD91_XENLA RDRDRHRE----------------------ILSRSKESTWALLHSVSDAFSGWMLMLLIG Q9PWK7_XENLA Q9PWK7_XENLA RDRDRHRE----------------------ILSRSKESTWALLHSVSDAFSGWMLMLLIG Q4LAL8_CANFA Q4LAL8_CANFA KDRERHRR----------------------INSKKKESAWEMTKSLYDAWSGWLVVTLTG Q4LAL7_CANFA Q4LAL7_CANFA KDRERHRR----------------------INSKKKESAWEMTKSLYDAWSGWLVVTLTG Q4R6L2_MACFA Q4R6L2_MACFA KDRERHRR----------------------INSKKKESAWEMTKSLYDAWSGWLVVTLTG B7Z932_HUMAN B7Z932_HUMAN KDRERHRR----------------------INSKKKESAWEMTKSLYDAWSGWLVVTLTG CLCN3_PONAB CLCN3_PONAB KDRERHRR----------------------INSKKKESAWEMTKSLYDAWSGWLVVTLTG B3KXK0_HUMAN B3KXK0_HUMAN KDRERHRR----------------------INSKKKESAWEMTKSLYDAWSGWLVVTLTG B9EGJ9_HUMAN B9EGJ9_HUMAN KDRERHRR----------------------INSKKKESAWEMTKSLYDAWSGWLVVTLTG Q8K4W9_MOUSE Q8K4W9_MOUSE KDRERHRR----------------------INSKKKESAWEMTKSLYDAWSGWLVVTLTG Q8K4W7_MOUSE Q8K4W7_MOUSE KDRERHRR----------------------INSKKKESAWEMTKSLYDAWSGWLVVTLTG P97274_CAVPO P97274_CAVPO KDRERHRR----------------------INSKKKESAWEMTKSLYDAWSGWLVVTLTG CLCN3_CAVPO CLCN3_CAVPO KDRERHRR----------------------INSKKKESAWEMTKSLYDAWSGWLVVTLTG Q6PEV2_MOUSE Q6PEV2_MOUSE KDRERHRR----------------------INSKKKESAWEMTKSLYDAWSGWLVVTLTG CLCN3_MOUSE CLCN3_MOUSE KDRERHRR----------------------INSKKKESAWEMTKSLYDAWSGWLVVTLTG Q3TTK0_MOUSE Q3TTK0_MOUSE KDRERHRR----------------------INSKKKESAWEMTKSLYDAWSGWLVVTLTG CLCN3_RAT CLCN3_RAT KDRERHRR----------------------INSKKKESAWEMTKSLYDAWSGWLVVTLTG Q8K4X1_MOUSE Q8K4X1_MOUSE KDRERHRR----------------------INSKKKESAWEMTKSLYDAWSGWLVVTLTG Q3TF45_MOUSE Q3TF45_MOUSE KDRERHRR----------------------INSKKKESAWEMTKSLYDAWSGWLVVTLTG Q3UEX5_MOUSE Q3UEX5_MOUSE KDRERHRR----------------------INSKKKESAWEMTKSLYDAWSGWLVVTLTG Q790S0_MOUSE Q790S0_MOUSE KDRERHRR----------------------INSKKKESAWEMTKSLYDAWSGWLVVTLTG Q6PGA5_MOUSE Q6PGA5_MOUSE KDRERHRR----------------------INSKKKESAWEMTKSLYDAWSGWLVVTLTG Q8K4W8_MOUSE Q8K4W8_MOUSE KDRERHRR----------------------INSKKKESAWEMTKSLYDAWSGWLVVTLTG B4F6X6_XENTR B4F6X6_XENTR KDRERHRR----------------------INSKKKESAWELAKSLYDAWSGWLVVTLTG A5PKR3_XENLA A5PKR3_XENLA KDRERHRR----------------------INSKKKESAWELAKSLYDAWSGWLVVTLTG Q9YH11_XENLA Q9YH11_XENLA KDRERHRR----------------------INSKKKESAWELAKSLYDAWSGWLVLTLTG A0PJS1_DANRE A0PJS1_DANRE KDRERHRK----------------------INSKKKESAWEFTKSLYDAWSGWLVVTLTG A1A5X0_DANRE A1A5X0_DANRE KDRERHRK----------------------INSKKKESAWEFTKSLYDAWSGWLVVTLTG Q4T7N7_TETNG Q4T7N7_TETNG KDRERHRK----------------------INSKKKESAWEFTKSLYDAWSGWLVVTLTG Q9PUI6_OREMO Q9PUI6_OREMO KDRERHRK----------------------INSKKKESAWEFTKNLYDAWSGWLVVTLTG Q08BG8_DANRE Q08BG8_DANRE KDTDRHRK----------------------ITSKSKESIWEFIKSLLDAWSGWLVMLLIG Q4SER7_TETNG Q4SER7_TETNG RDTDRHRKVCPASARRSAARVPALTVFSSQITSKSKESIWELIKSLLDAWSGWVVMLLIG B0BMM3_XENTR B0BMM3_XENTR RDTDRHRK----------------------ITSKSKESIWEFIKGLLDAWSGWVVMLLIG Q4F894_BOVIN Q4F894_BOVIN RDTDRHRK----------------------ITSKSKESIWEFIKSLLDAWSGWAVMLLIG B7Z5Z4_HUMAN B7Z5Z4_HUMAN ------------------------------------------------------------ Q4G0X3_HUMAN Q4G0X3_HUMAN RDTDRHRK----------------------ITSKSKESIWEFIKSLLDAWSGWVVMLLIG A1L3U1_HUMAN A1L3U1_HUMAN RDTDRHRK----------------------ITSKSKESIWEFIKSLLDAWSGWVVMLLIG CLCN4_HUMAN CLCN4_HUMAN RDTDRHRK----------------------ITSKSKESIWEFIKSLLDAWSGWVVMLLIG CLCN4_RAT CLCN4_RAT RDTDRHRK----------------------ITSKSKESIWEFIKSLLDAWSGWVVMLLIG Q56A19_RAT Q56A19_RAT RDTDRHRK----------------------ITSKSKESIWEFIKSLLDAWSGWVVMLLIG CLCN4_MOUSE CLCN4_MOUSE RDTDRHRK----------------------ITSKSKESIWEFIKSLLDAWSGWVVMLLIG Q3LRV6_MOUSE Q3LRV6_MOUSE -------------------------------------------------------MLLIG Q8CBL5_MOUSE Q8CBL5_MOUSE RDTDRHRK----------------------ITSKSKESIWEFIKSLLDAWSGWVVMLLIG Q99JZ2_MOUSE Q99JZ2_MOUSE RDTDRHRK----------------------ITSKSKESIWEFIKSLLDAWSGWVVMLLIG Q2TAX6_MOUSE Q2TAX6_MOUSE RDTDRHRK----------------------ITSKSKESIWEFIKSLLDAWSGWVVMLLIG MATCH CONSENSUS ?D??RHR???????????????????????I??K?KES?W????S??DA?SGW????L?G

Q869D8_ASCSS Q869D8_ASCSS LA---------------------------AGTCAGLIDTTAKWLGDLKVGKCSTFFYMDK Q4SXZ6_TETNG Q4SXZ6_TETNG LMAGIPAGPDSRVSLNPAGMLQLPVAPGGSGALAGGIDIAAHWLTDMKEGVCLRGFWFNR Q9PUI5_OREMO Q9PUI5_OREMO LM---------------------------SGALAGGIDISAHWMTDVKGGLCLRGFWFNH CLCN5_CAVPO CLCN5_CAVPO LL---------------------------SGSLAGLIDISAHWMTDLKEGICTEGFWFNH CLCN5_PIG CLCN5_PIG LL---------------------------SGSLAGLIDISAHWMTDLKEGICTEGLWFNH CLCN5_RABIT CLCN5_RABIT LF---------------------------SGSLAGLIDISAHWMTDLKEGICTGGFWFNH CLCN5_RAT CLCN5_RAT LL---------------------------SGSLAGLIDISAHWMTDLKEGICTGGFWFNH Q8CI67_MOUSE Q8CI67_MOUSE LL---------------------------SGSLAGLIDISAHWMTDLKEGICTGGFWFNH Q3UL16_MOUSE Q3UL16_MOUSE LL---------------------------SGSLAGLIDISAHWMTDLKEGICTGGFWFNH B1ATV0_MOUSE B1ATV0_MOUSE LL---------------------------SGSLAGLIDISAHWMTDLKEGICTGGFWFNH CLCN5_MOUSE CLCN5_MOUSE LL---------------------------SGSLAGLIDISAHWMTDLKEGICTGGFWFNH Q8C6W8_MOUSE Q8C6W8_MOUSE LL---------------------------SGSLAGLIDISAHWMTDLKEGICTGGFWFNH B3KRR2_HUMAN B3KRR2_HUMAN IV---------------------------AGTLS---------MSPLK------------ B3KPN6_HUMAN B3KPN6_HUMAN LL---------------------------SGSLAGLIDISAHWMTDLKEGICTGGFWFNH A8K4H5_HUMAN A8K4H5_HUMAN LL---------------------------SGSLAGLIDISAHWMTDLKEGICTGGFWFNH CLCN5_HUMAN CLCN5_HUMAN LL---------------------------SGSLAGLIDISAHWMTDLKEGICTGGFWFNH CLCN5_PONAB CLCN5_PONAB LL---------------------------SGSLAGLIDISAHWMTDLKEGICTGGFWFNH Q28C29_XENTR Q28C29_XENTR LT---------------------------AGSLAGLIDISSHWMTDLKEGICLPWFWFNH O13080_XENLA O13080_XENLA LT---------------------------AGSLAGLIDISSHWMTDLKEGICLPWFWFNH A2BD91_XENLA A2BD91_XENLA LT---------------------------AGSLAGLIDISSHWMTDLKEGICLPWFWFNH Q9PWK7_XENLA Q9PWK7_XENLA LT---------------------------AGSLAGLIDISSHWMTDLKEGICLPWFWFNH Q4LAL8_CANFA Q4LAL8_CANFA LA---------------------------SGALAGLIDIAADWMTDLKEGICLSALWYNH Q4LAL7_CANFA Q4LAL7_CANFA LA---------------------------SGALAGLIDIAADWMTDLKEGICLSALWYNH Q4R6L2_MACFA Q4R6L2_MACFA LA---------------------------SGALAGLIDIAADWMTDLKEGICLSALWYNH B7Z932_HUMAN B7Z932_HUMAN LA---------------------------SGALAGLIDIAADWMTDLKEGICLSALWYNH CLCN3_PONAB CLCN3_PONAB LA---------------------------SGALAGLIDIAADWMTDLKEGICLSALWYNH B3KXK0_HUMAN B3KXK0_HUMAN LA---------------------------SGALAGLIDIAADWMTDLKEGICLSALWYNH B9EGJ9_HUMAN B9EGJ9_HUMAN LA---------------------------SGALAGLIDIAADWMTDLKEGICLSALWYNH Q8K4W9_MOUSE Q8K4W9_MOUSE LA---------------------------SGALAGLIDIAADWMTDLKEGICLSALWYNH Q8K4W7_MOUSE Q8K4W7_MOUSE LA---------------------------SGALAGLIDIAADWMTDLKEGICLSALWYNH P97274_CAVPO P97274_CAVPO LA---------------------------SGALAGLIDIAADWMTDLKEGICLSALWYNH CLCN3_CAVPO CLCN3_CAVPO LA---------------------------SGALAGLIDIAADWMTDLKEGICLSALWYNH Q6PEV2_MOUSE Q6PEV2_MOUSE LA---------------------------SGALAGLIDIAADWMTDLKEGICLSALWYNH CLCN3_MOUSE CLCN3_MOUSE LA---------------------------SGALAGLIDIAADWMTDLKEGICLSALWYNH Q3TTK0_MOUSE Q3TTK0_MOUSE LA---------------------------SGALAGLIDIAADWMTDLKEGICLSALWYNH CLCN3_RAT CLCN3_RAT LA---------------------------SGALAGLIDIAADWMTDLKEGICLSALWYNH Q8K4X1_MOUSE Q8K4X1_MOUSE LA---------------------------SGALAGLIDIAADWMTDLKEGICLSALWYNH Q3TF45_MOUSE Q3TF45_MOUSE LA---------------------------SGALAGLIDIAADWMTDLKEGICLSALWYNH Q3UEX5_MOUSE Q3UEX5_MOUSE LA---------------------------SGALAGLIDIAADWMTDLKEGICLSALWYNH Q790S0_MOUSE Q790S0_MOUSE LA---------------------------SGALAGLIDIAADWMTDLKEGICLSALWYNH Q6PGA5_MOUSE Q6PGA5_MOUSE LA---------------------------SGALAGLIDIAADWMTDLKEGICLSALWYNH Q8K4W8_MOUSE Q8K4W8_MOUSE LA---------------------------SGALAGLIDIAADWMTDLKEGICLSALWYNH B4F6X6_XENTR B4F6X6_XENTR LA---------------------------SGALAGFIDIAADWMADLKEGICMTAFWFNH A5PKR3_XENLA A5PKR3_XENLA LA---------------------------SGALAGFIDIAADWMADLKEGICMTAFWFNH Q9YH11_XENLA Q9YH11_XENLA LA---------------------------SGALAGFIDIAADWMADLKEGICMTAFWFNH A0PJS1_DANRE A0PJS1_DANRE LA---------------------------SGALAGGIDIAADWMNDLKEGVCLSAMWFNH A1A5X0_DANRE A1A5X0_DANRE LA---------------------------SGALAGGIDIAADWMNDLKEGVCLSAMWFNH Q4T7N7_TETNG Q4T7N7_TETNG LA---------------------------SGALAGLIDIAADWMNDLKEGVCLSALWFNH Q9PUI6_OREMO Q9PUI6_OREMO LA---------------------------SGALAGLIDIAADWMNDLKEGVCLSALWFNH Q08BG8_DANRE Q08BG8_DANRE LL---------------------------SGTLAGVIDLAVDWMTDLKEGVCLSAFWYSH Q4SER7_TETNG Q4SER7_TETNG LLSGQSGRAPPRGPLGVLTAALAP-----AGTLAGVIDLAVDWMTDLKEGVCLSAFWYSH B0BMM3_XENTR B0BMM3_XENTR LL---------------------------AGTLAGVIDLAVDWMTDLKEGICLNAFWYSH Q4F894_BOVIN Q4F894_BOVIN LL---------------------------AGTLAGVIDLAVDWMTDLKEGICLSAFWYSH B7Z5Z4_HUMAN B7Z5Z4_HUMAN -------------------------------------------MTDLKEGVCLSAFWYSH Q4G0X3_HUMAN Q4G0X3_HUMAN LL---------------------------AGTLAGVIDLAVDWMTDLKEGVCLSAFWYSH A1L3U1_HUMAN A1L3U1_HUMAN LL---------------------------AGTLAGVIDLAVDWMTDLKEGVCLSAFWYSH CLCN4_HUMAN CLCN4_HUMAN LL---------------------------AGTLAGVIDLAVDWMTDLKEGVCLSAFWYSH CLCN4_RAT CLCN4_RAT LL---------------------------AGTLAGVIDLAVDWMTDLKEGVCLSAFWYSH Q56A19_RAT Q56A19_RAT LL---------------------------AGTLAGVIDLAVDWMTDLKEGVCLSAFWYSH CLCN4_MOUSE CLCN4_MOUSE LL---------------------------AGTLAGVIDLAVDWMTDLKEGVCLSAFWYSH Q3LRV6_MOUSE Q3LRV6_MOUSE LL---------------------------AGTLAGVIDLAVDWMTDLKEGVCLSAFWYSH Q8CBL5_MOUSE Q8CBL5_MOUSE LL---------------------------AGTLAGVIDLAVDWMTDLKEGVCLSAFWYSH Q99JZ2_MOUSE Q99JZ2_MOUSE LL---------------------------AGTLAGVIDLAVDWMTDLKEGVCLSAFWYSH Q2TAX6_MOUSE Q2TAX6_MOUSE LL---------------------------AGTLAGVIDLAVDWMTDLKEGVCLSAFWYSH MATCH : :* CONSENSUS L?????????????????????????????G?LAG?ID????WMTDLKEG?C????W??H

Q869D8_ASCSS Q869D8_ASCSS YACCWNVQ----LDRRKCPEWQTWAEIFVNLTEGQ-TYAFNYFAYVVGAIILSTLAAILV Q4SXZ6_TETNG Q4SXZ6_TETNG EHCCWTS-ETTFQDRDRCAVWQTWGELITGTSEGALSYILNYLLYIVWALLFAFLAVTLV Q9PUI5_OREMO Q9PUI5_OREMO EHCCWLSNETTFQERDRCPQWQSWAELITGKSEGPFAYIVNYLMYIFWALMFSFLAVILV CLCN5_CAVPO CLCN5_CAVPO EHCCWNSQQVTFEDRDKCPEWNSWSQLIINMDEGAFAYIVNYFMYVLWALLFAFLAVSLV CLCN5_PIG CLCN5_PIG EHCCWNSKHVTFKDRDKCPEWNSWSQLIISADEGAFAYIVNYFMYVLWALLFAFLAVSLV CLCN5_RABIT CLCN5_RABIT EHCCWNSENVTFEDTDKCPEWNSWSQLIINTDEGAFAYIVNYFMYVLWALLFAFLAVSLV CLCN5_RAT CLCN5_RAT EHCCWNSEHVTFEDRDKCPEWNSWSQLIISTDQGAFAYIVNYFMYVLWALLFAFLAVSLV Q8CI67_MOUSE Q8CI67_MOUSE EHCCWNSEHVTFEHRDKCPEWNTWAQLIINTDQGAFAYIVNYFMYVLWALLFAFLAVSLV Q3UL16_MOUSE Q3UL16_MOUSE EHCCWNSEHVTFEHRDKCPEWNSWAQLIINTDQGAFAYIVNYFMYVLWALLFAFLAVSLV B1ATV0_MOUSE B1ATV0_MOUSE EHCCWNSEHVTFEHRDKCPEWNSWAQLIINTDQGAFAYIVNYFMYVLWALLFAFLAVSLV CLCN5_MOUSE CLCN5_MOUSE EHCCWNSEHVTFEHRDKCPEWNSWAQLIINTDQGAFAYIVNYFMYVLWALLFAFLAVSLV Q8C6W8_MOUSE Q8C6W8_MOUSE EHCCWNSEHVTFEHRDKCPEWNSWAQLIINTDQGAFAYIVNYFMYVLWALLFAFLAVSLV B3KRR2_HUMAN B3KRR2_HUMAN --------------RDKCPEWNSWSQLIISTDEGAFAYIVNYFMYVLWALLFAFLAVSLV B3KPN6_HUMAN B3KPN6_HUMAN EHCCWNSEHVTFEERDKCPEWNSWSQLIISTDEGAFAYIVNYFMYVLWALLFAFLAVSLV A8K4H5_HUMAN A8K4H5_HUMAN EHCCWNSEHVTFEERDKCPEWNSWSQLIISTDEGAFAYIVNYFMYVLWALLFAFLAVSLV CLCN5_HUMAN CLCN5_HUMAN EHCCWNSEHVTFEERDKCPEWNSWSQLIISTDEGAFAYIVNYFMYVLWALLFAFLAVSLV CLCN5_PONAB CLCN5_PONAB EHCCWNSEHVTFEERDKCPEWNSWSQLIISTDEGAFAYIVNYFMYVLWALLFAFLAVSLV Q28C29_XENTR Q28C29_XENTR EQCCWQSNNVTFEDRNNCPEWRSWSQLVLGRSEGAFPYILNYFMYVLWALLFSLLAVLLV O13080_XENLA O13080_XENLA EQCCWQSNNVTFEDRNNCPEWRSWSQLVLGRSEGAFPYILNYFMYVMWALLFSLLAVLLV A2BD91_XENLA A2BD91_XENLA EQCCWQSNNVTFEDRNNCPEWRSWSQLVLGRSEGAFPYILNYFMYVMWALLFSLLAVLLV Q9PWK7_XENLA Q9PWK7_XENLA EQCCWQSNNVTFEDRNNCPEWRSWSQLVLGRSEGAFPYILNYFMYVMWALLFSLLAVLLV Q4LAL8_CANFA Q4LAL8_CANFA EQCCWGSNETTFEERDKCPQWKTWAELIIGQAEGPGSYIMNYIMYIFWALGFAFLAVSLV Q4LAL7_CANFA Q4LAL7_CANFA EQCCWGSNETTFEERDKCPQWKTWAELIIGQAEGPGSYIMNYIMYIFWALGFAFLAVSLV Q4R6L2_MACFA Q4R6L2_MACFA EQCCWGSNETTFEERDKCPQWKTWAELIIGQAEGPGSYIMNYIMYIFWALSFAFLAVSLV B7Z932_HUMAN B7Z932_HUMAN EQCCWGSNETTFEERDKCPQWKTWAELIIGQAEGPGSYIMNYIMYIFWALSFAFLAVSLV CLCN3_PONAB CLCN3_PONAB EQCCWGSNETTFEERDKCPQWKTWAELIIGQAEGPGSYIMNYIMYIFWALSFAFLAVSLV B3KXK0_HUMAN B3KXK0_HUMAN EQCCWGSNETTFEERDKCPQWKTWAELIIGQAEGPGSYIMNYIMYIFWALSFAFLAVSLV B9EGJ9_HUMAN B9EGJ9_HUMAN EQCCWGSNETTFEERDKCPQWKTWAELIIGQAEGPGSYIMNYIMYIFWALSFAFLAVSLV Q8K4W9_MOUSE Q8K4W9_MOUSE EQCCWGSNETTFEERDKCPQWKTWAELIIGQAEGPGSYIMNYIMYIFWALSFAFLAVSLV Q8K4W7_MOUSE Q8K4W7_MOUSE EQCCWGSNETTFEERDKCPQWKTWAELIIGQAEGPGSYIMNYIMYIFWALSFAFLAVSLV P97274_CAVPO P97274_CAVPO EQCCWGSNETTFEERDKCPQWKTWAELIIGQAEGPGSYIMNYIMYIFWALSFAFLAVSLV CLCN3_CAVPO CLCN3_CAVPO EQCCWGSNETTFEERDKCPQWKTWAELIIGQAEGPGSYIMNYIMYIFWALSFAFLAVSLV Q6PEV2_MOUSE Q6PEV2_MOUSE EQCCWGSNETTFEERDKCPQWKTWAELIIGQAEGPGSYIMNYIMYIFWALSFAFLAVSLV CLCN3_MOUSE CLCN3_MOUSE EQCCWGSNETTFEERDKCPQWKTWAELIIGQAEGPGSYIMNYIMYIFWALSFAFLAVSLV Q3TTK0_MOUSE Q3TTK0_MOUSE EQCCWGSNETTFEERDKCPQWKTWAELIIGQAEGPGSYIMNYIMYIFWALSFAFLAVSLV CLCN3_RAT CLCN3_RAT EQCCWGSNETTFEERDKCPQWKTWAELIIGQAEGPGSYIMNYIMYIFWALSFAFLAVSLV Q8K4X1_MOUSE Q8K4X1_MOUSE EQCCWGSNETTFEERDKCPQWKTWAELIIGQAEGPGSYIMNYIMYIFWALSFAFLAVSLV Q3TF45_MOUSE Q3TF45_MOUSE EQCCWGSNETTFEERDKCPQWKTWAELIIGQAEGPGSYIMNYIMYIFWALSFAFLAVSLV Q3UEX5_MOUSE Q3UEX5_MOUSE EQCCWGSNETTFEERDKCPQWKTWAELIIGQAEGPGSYIMNYIMYIFWALSFAFLAVSLV Q790S0_MOUSE Q790S0_MOUSE EQCCWGSNETTFEERDKCPQWKTWAELIIGQAEGPGSYIMNYIMYIFWALSFAFLAVSLV Q6PGA5_MOUSE Q6PGA5_MOUSE EQCCWGSNETTFEERDKCPQWKTWAELIIGQAEGPGFYIMNYIMYIFWALSFAFLAVSLV Q8K4W8_MOUSE Q8K4W8_MOUSE EQCCWGSNETTFEERDKCPQWKTWAELIIGQAEGPGSYIMNYIMYIFWALSFAFLAVSLV B4F6X6_XENTR B4F6X6_XENTR EQCCWDSKEATFEERDKCPQWQTWADLIIGQAEGPGSYIMNYIMYIFWALSFAFLAVCLV A5PKR3_XENLA A5PKR3_XENLA EQCCWDSKEATFEERDKCPQWQTWADLIIGQAEGPGSYIMNYFMYIFWALSFAFLAVCLV Q9YH11_XENLA Q9YH11_XENLA EQCCWDSKEATFEERDKCPQWQTWADLIIGQAEGPGSYIMNYFMYIFWALSFAFLAVCLV A0PJS1_DANRE A0PJS1_DANRE EQCCWGSNKTTFAERDKCPQWKTWAELILGQEQGPGSYIMNYFMFTFWALSFAFLAVSLV A1A5X0_DANRE A1A5X0_DANRE EQCCWGSNKTTFAERDKCPQWKTWAELILGQEQGPGSYIMNYFMFTFWALSFAFLAVSLV Q4T7N7_TETNG Q4T7N7_TETNG EQCCWTSNETTFAERDKCPQWKSWAELILGQAEGPGSYIMNYFMYIYWALSFAFLAVCLV Q9PUI6_OREMO Q9PUI6_OREMO EQCCWTSNETTFAERDKCPQWKSWAELILGQAEGPGSYIMNYFMYIYWALSFAFLAVCLV Q08BG8_DANRE Q08BG8_DANRE EQCCWTSNETTFADRDKCPQWQKWAELVTGYTEGAGVYVLNYFLYVLWALFFSFLAVSLV Q4SER7_TETNG Q4SER7_TETNG EQCCWTSNETTFDDRDKCPQWQKWAELMTGHTEGAGAYVLNYFLYVLWALLFSFLAVSLV B0BMM3_XENTR B0BMM3_XENTR EQCCWTSDETTFEDRDKCPQWQKWSELMIDQSEGASAYILNYFLYIMWALSFAFLAVSLV Q4F894_BOVIN Q4F894_BOVIN EQCCWTSNETTFEDRDKCPLWQKWSELLVNQSEGASAYILNYLMYILWALLFAFLAVSLV B7Z5Z4_HUMAN B7Z5Z4_HUMAN EQCCWTSNETTFEDRDKCPLWQKWSELLVNQSEGASAYILNYLMYILWALLFAFLAVSLV Q4G0X3_HUMAN Q4G0X3_HUMAN EQCCWTSNETTFEDRDKCPLWQKWSELLVNQSEGASAYILNYLMYILWALLFAFLAVSLV A1L3U1_HUMAN A1L3U1_HUMAN EQCCWTSNETTFEDRDKCPLWQKWSELLVNQSEGASAYILNYLMYILWALLFAFLAVSLV CLCN4_HUMAN CLCN4_HUMAN EQCCWTSNETTFEDRDKCPLWQKWSELLVNQSEGASAYILNYLMYILWALLFAFLAVSLV CLCN4_RAT CLCN4_RAT EQCCWTSNETTFEDRDKCPLWQKWSELLLSQSEGASAYILNYLMYILWALLFAFLAVSLV Q56A19_RAT Q56A19_RAT EQCCWTSNETTFEDRDKCPLWQKWSELLLSQSEGASAYILNYLMYILWALLFAFLAVSLV CLCN4_MOUSE CLCN4_MOUSE EQCCWTSNETTFEDRDKCPLWQKWSELLLSQSEGASAYILNYLMYILWALLFAFLAVSLV Q3LRV6_MOUSE Q3LRV6_MOUSE EQCCWTSNETTFEDRDKCPLWQKWSELLLSQSEGASAYILNYLMYILWALLFAFLAVSLV Q8CBL5_MOUSE Q8CBL5_MOUSE EQCCWTSNETTFEDRDKCPLWQKWSELLLSQSEGASAYILNYLMYILWALLFAFLAVSLV Q99JZ2_MOUSE Q99JZ2_MOUSE EQCCWTSNETTFEDRDKCPLWQKWSELLLSQSEGASAYILNYLMYILWALLFAFLAVSLV Q2TAX6_MOUSE Q2TAX6_MOUSE EQCCWTSNETTFEDRDKCPLWQKWSELLLSQSEGASAYILNYLMYILWALLFAFLAVSLV MATCH .*. *..*.::. . :* * .**: : *: :: **. ** CONSENSUS E?CCW?S???TFE?RDKCP?W??W??L?????EG???YI?NY?MY??WAL?FAFLAVSLV

Q869D8_ASCSS Q869D8_ASCSS KGYAPYACGSGIPEVKTILGGFIIRGYLGKWTLLIKTVTAPMAVASNLSLGKEGPLVHIS Q4SXZ6_TETNG Q4SXZ6_TETNG RAFAPYACGSGIPEIKTILSGFIIRGYLGKWTLITKTVTLVLAVSSGLSLGKEGPLVHVA Q9PUI5_OREMO Q9PUI5_OREMO RAFAPYACGSGIPEIKTILSGFIIRGYLGKWTLIIKTITLVLAVSSGLSLGKEGPLVHVA CLCN5_CAVPO CLCN5_CAVPO KVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLIIKTITLVLAVSSGLSLGKEGPLVHVA CLCN5_PIG CLCN5_PIG KVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLIIKTITLVLAVSSGLSLGKEGPLVHVA CLCN5_RABIT CLCN5_RABIT KVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLVIKTITLVLAVSSGLSLGKEGPLVHVA CLCN5_RAT CLCN5_RAT KAFAPYACGSGIPEIKTILSGFIIRGYLGKWTLVIKTITLVLAVSSGLSLGKEGPLVHVA Q8CI67_MOUSE Q8CI67_MOUSE KAFAPYACGSGIPEIKTILSGFIIRGYLGKWTLVIKTITLVLAVSSGLSLGKEGPLVHVA Q3UL16_MOUSE Q3UL16_MOUSE KAFAPYACGSGIPEIKTILSGFIIRGYLGKWTLVIKTITLVLAVSSGLSLGKEGPLVHVA B1ATV0_MOUSE B1ATV0_MOUSE KAFAPYACGSGIPEIKTILSGFIIRGYLGKWTLVIKTITLVLAVSSGLSLGKEGPLVHVA CLCN5_MOUSE CLCN5_MOUSE KAFAPYACGSGIPEIKTILSGFIIRGYLGKWTLVIKTITLVLAVSSGLSLGKEGPLVHVA Q8C6W8_MOUSE Q8C6W8_MOUSE KAFAPYACGSGIPEIKTILSGFIIRGYLGKWTLVIKTITLVLAVSSGLSLGKEGPLVHVA B3KRR2_HUMAN B3KRR2_HUMAN KVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLVIKTITLVLAVSSGLSLGKEGPLVHVA B3KPN6_HUMAN B3KPN6_HUMAN KVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLVIKTITLVLAVSSGLSLGKEGPLVHVA A8K4H5_HUMAN A8K4H5_HUMAN KVFAPYACGSGIPEIKTILSVFIIRGYLGKWTLVIKTITLVLAVSSGLSLGKEGPLVHVA CLCN5_HUMAN CLCN5_HUMAN KVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLVIKTITLVLAVSSGLSLGKEGPLVHVA CLCN5_PONAB CLCN5_PONAB KVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLVIKTITLVLAVSSGLSLGKEGPLVHVA Q28C29_XENTR Q28C29_XENTR RNFAPYACGSGIPEIKTILSGFIIRGYLGKWTLIIKTMTLVLAVSSGLSLGKEGPLIHVA O13080_XENLA O13080_XENLA RNFAPYACGSGIPEIKTILSGFIIRGYLGKWTLIIKTMTLVLAVSSGLSLGKEGPLIHVA A2BD91_XENLA A2BD91_XENLA RNFAPYACGSGIPEIKTILSGFIIRGYLGKWTLIIKTMTLVLAVSSGLSLGKEGPLIHVA Q9PWK7_XENLA Q9PWK7_XENLA RNFAPYACGSGIPEIKTILSGFIIRGYLGKWTLIIKTMTLVLAVSSGLSLGKEGPLIHVA Q4LAL8_CANFA Q4LAL8_CANFA KVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLMIKTITLVLAVASGLSLGKEGPLVHVA Q4LAL7_CANFA Q4LAL7_CANFA KVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLMIKTITLVLAVASGLSLGKEGPLVHVA Q4R6L2_MACFA Q4R6L2_MACFA KVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLMIKTITLVLAVASGLSLGKEGPLVHVA B7Z932_HUMAN B7Z932_HUMAN KVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLMIKTITLVLAVASGLSLGKEGPLVHVA CLCN3_PONAB CLCN3_PONAB KVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLMIKTVTLVLAVASGLSLGKEGPLVHVA B3KXK0_HUMAN B3KXK0_HUMAN KVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLMIKTITLVLAVASGLSLGKEGPLVHVA B9EGJ9_HUMAN B9EGJ9_HUMAN KVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLMIKTITLVLAVASGLSLGKEGPLVHVA Q8K4W9_MOUSE Q8K4W9_MOUSE KVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLMIKTITLVLAVASGLSLGKEGPLVHVA Q8K4W7_MOUSE Q8K4W7_MOUSE KVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLMIKTITLVLAVASGLSLGKEGPLVHVA P97274_CAVPO P97274_CAVPO KVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLMIKTITLVLAVASGLSLGKEGPLVHVA CLCN3_CAVPO CLCN3_CAVPO KVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLMIKTITLVLAVASGLSLGKEGPLVHVA Q6PEV2_MOUSE Q6PEV2_MOUSE KVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLMIKTITLVLAVASGLSLGKEGPLVHVA CLCN3_MOUSE CLCN3_MOUSE KVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLMIKTITLVLAVASGLSLGKEGPLVHVA Q3TTK0_MOUSE Q3TTK0_MOUSE KVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLMIKTITLVLAVASGLSLGKEGPLVHVA CLCN3_RAT CLCN3_RAT KVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLMIKTITLVLAVASGLSLGKEGPLVHVA Q8K4X1_MOUSE Q8K4X1_MOUSE KVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLMIKTITLVLAVASGLSLGKEGPLVHVA Q3TF45_MOUSE Q3TF45_MOUSE KVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLMIKTITLVLAVASGLSLGKEGPLVHVA Q3UEX5_MOUSE Q3UEX5_MOUSE KVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLMIKTITLVLAVASGLSLGKEGPLVHVA Q790S0_MOUSE Q790S0_MOUSE KVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLMIKTITLVLAVASGLSLGKEGPLVHVA Q6PGA5_MOUSE Q6PGA5_MOUSE KVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLMIKTITLVLAVASGLSLGKEGPLVHVA Q8K4W8_MOUSE Q8K4W8_MOUSE KVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLMIKTITLVLAVASGLSLGKEGPLVHVA B4F6X6_XENTR B4F6X6_XENTR KVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLMIKTVTLVLAVASGLSLGKEGPLVHVA A5PKR3_XENLA A5PKR3_XENLA KVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLMIKTITLVLAVASGLSLGKEGPLVHVA Q9YH11_XENLA Q9YH11_XENLA KVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLMIKTITLVLAVASGLSLGKEGPLVHVA A0PJS1_DANRE A0PJS1_DANRE KVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLMIKTITLVLAVASGLSLGKEGPLVHVA A1A5X0_DANRE A1A5X0_DANRE KVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLMIKTITLVLAVASGLSLGKEGPLVHVA Q4T7N7_TETNG Q4T7N7_TETNG KVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLMIKTITLVLAVASGLSLGKEGPLVHVA Q9PUI6_OREMO Q9PUI6_OREMO KVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLMIKTITLVLAVASGLSLGKEGPLVHVA Q08BG8_DANRE Q08BG8_DANRE RVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLLIKTVTLVLAVSSGLSLGKEGPLVHVA Q4SER7_TETNG Q4SER7_TETNG RVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLLIKTVTLVLAVSSGLSLGKEGPLVHVA B0BMM3_XENTR B0BMM3_XENTR RVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLLIKTVTLVLVVSSGLSLGKEGPSVHVA Q4F894_BOVIN Q4F894_BOVIN RVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLLIKTVTLVLVVSSGLSLGKEGPLVHVA B7Z5Z4_HUMAN B7Z5Z4_HUMAN RVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLLIKTVTLVLVVSSGLSLGKEGPLVHVA Q4G0X3_HUMAN Q4G0X3_HUMAN RVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLLIKTVTLVLVVSYGLSLGKEGPLVHVA A1L3U1_HUMAN A1L3U1_HUMAN RVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLLIKTVTLVLVVSSGLSLGKEGPLVHVA CLCN4_HUMAN CLCN4_HUMAN RVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLLIKTVTLVLVVSSGLSLGKEGPLVHVA CLCN4_RAT CLCN4_RAT RVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLLIKTVTLVLVVSSGLSLGKEGPLVHVA Q56A19_RAT Q56A19_RAT RVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLLIKTVTLVLVVSSGLSLGKEGPLVHVA CLCN4_MOUSE CLCN4_MOUSE RVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLLIKTVTLVLVVSSGLSLGKEGPLVHVA Q3LRV6_MOUSE Q3LRV6_MOUSE RVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLLIKTVTLVLVVSSGLSLGKEGPLVHVA Q8CBL5_MOUSE Q8CBL5_MOUSE RVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLLIKTVTLVLVVSSGLSLGKEGPLVHVA Q99JZ2_MOUSE Q99JZ2_MOUSE RVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLLIKTVTLVLVVSSGLSLGKEGPLVHVA Q2TAX6_MOUSE Q2TAX6_MOUSE RVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLLIKTVTLVLVVSSGLSLGKEGPLVHVA MATCH : :***********:****. ************: **:* :.*: .******** :*:: CONSENSUS ??FAPYACGSGIPEIKTILSGFIIRGYLGKWTL?IKT?TLVL?V?SGLSLGKEGPLVHVA

Q869D8_ASCSS Q869D8_ASCSS ACCGNVFSALFPKYYSNEAKKREMLSAAAAAGVSVAFGVPVGGVLFSLEECSYYFPMKTL Q4SXZ6_TETNG Q4SXZ6_TETNG CCCANILCHLFTKYRKNEAKRREVLSAAAAVGVSVAFGAPIGGVLFSLEEVSYYFPLKTL Q9PUI5_OREMO Q9PUI5_OREMO CCCANILCHLFTKYRKNEAKRREVLSAAAAVGVSVAFGAPIGGVLFSLEEVSYYFPLKTL CLCN5_CAVPO CLCN5_CAVPO CCCGNILCHCFNKYRENEAKRREVLSAAAAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTL CLCN5_PIG CLCN5_PIG CCCGNILCHCFNKYRKNEAKRREVLSAAAAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTL CLCN5_RABIT CLCN5_RABIT CCCGNILCHRFNKYRKNEAKRREVLSAAAAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTL CLCN5_RAT CLCN5_RAT CCCGNILCHCFNKYRKNEAKRREVLSAAAAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTL Q8CI67_MOUSE Q8CI67_MOUSE CCCGNILCHCFNKYRKNEAKRREVLSAAAAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTL Q3UL16_MOUSE Q3UL16_MOUSE CCCGNILCHCFNKYRKNEAKRREVLSAAAAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTL B1ATV0_MOUSE B1ATV0_MOUSE CCCGNILCHCFNKYRKNEAKRREVLSAAAAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTL CLCN5_MOUSE CLCN5_MOUSE CCCGNILCHCFNKYRKNEAKRREVLSAAAAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTL Q8C6W8_MOUSE Q8C6W8_MOUSE CCCGNILCHCFNKYRKNEAKRREVLSAAAAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTL B3KRR2_HUMAN B3KRR2_HUMAN CCCGNILCHCFNKYRKNEAKRREVLSAAAAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTL B3KPN6_HUMAN B3KPN6_HUMAN CCCGNILCHCFNKYRKNEAKRREVLSAAAAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTL A8K4H5_HUMAN A8K4H5_HUMAN CCCGNILCHCFNKYGKNEAKRREVLSAAAAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTL CLCN5_HUMAN CLCN5_HUMAN CCCGNILCHCFNKYRKNEAKRREVLSAAAAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTL CLCN5_PONAB CLCN5_PONAB CCCGNILCHCFNKYRKNEAKRREVLSAAAAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTL Q28C29_XENTR Q28C29_XENTR CCCGNILCHLFTKYRKNEAKRREVLSAAAAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTL O13080_XENLA O13080_XENLA CCCGNILCHLFTKYRKNEAKRREVLSAAAAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTL A2BD91_XENLA A2BD91_XENLA CCCGNILCHLFTKYRKNEAKRREVLSAAAAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTL Q9PWK7_XENLA Q9PWK7_XENLA CCCGNILCHLFTKYRKNEAKRREVLSAAAAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTL Q4LAL8_CANFA Q4LAL8_CANFA CCCGNIFSYLFPKYSTNEAKKREVLSAASAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTL Q4LAL7_CANFA Q4LAL7_CANFA CCCGNIFSYLFPKYSTNEAKKREVLSAASAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTL Q4R6L2_MACFA Q4R6L2_MACFA CCCGNIFSYLFPKYSTNEAKKREVLSAASAAGVSVAF----------------------- B7Z932_HUMAN B7Z932_HUMAN CCCGNIFSYLFPKYSTNEAKKREV---------------------------SYYFPLKTL CLCN3_PONAB CLCN3_PONAB CCCGNIFSYLFPKYSTNEAKKREVLSAASAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTL B3KXK0_HUMAN B3KXK0_HUMAN CCCGNIFSYLFPKYSTNEAKKREVLSAASAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTL B9EGJ9_HUMAN B9EGJ9_HUMAN CCCGNIFSYLFPKYSTNEAKKREVLSAASAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTL Q8K4W9_MOUSE Q8K4W9_MOUSE CCCGNIFSYLFPKYSTNEAKKREVLSAASAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTL Q8K4W7_MOUSE Q8K4W7_MOUSE CCCGNIFSYLFPKYSTNEAKKREVLSAASAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTL P97274_CAVPO P97274_CAVPO CCCGNIFSYLFPKYSTNEAKKREVLSAASAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTL CLCN3_CAVPO CLCN3_CAVPO CCCGNIFSYLFPKYSTNEAKKREVLSAASAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTL Q6PEV2_MOUSE Q6PEV2_MOUSE CCCGNIFSYLFPKYSTNEAKKREVLSAASAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTL CLCN3_MOUSE CLCN3_MOUSE CCCGNIFSYLFPKYSTNEAKKREVLSAASAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTL Q3TTK0_MOUSE Q3TTK0_MOUSE CCCGNIFSYLFPKYSTNEAKKREVLSAASAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTL CLCN3_RAT CLCN3_RAT CCCGNIFSYLFPKYSTNEAKKREVLSAASAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTL Q8K4X1_MOUSE Q8K4X1_MOUSE CCCGNIFSYLFPKYSTNEAKKREVLSAASAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTL Q3TF45_MOUSE Q3TF45_MOUSE CCCGNIFSYLFPKYSTNEAKKREVLSAASAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTL Q3UEX5_MOUSE Q3UEX5_MOUSE CCCGNIFSYLFPKYSTNEAKKREVLSAASAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTL Q790S0_MOUSE Q790S0_MOUSE CCCGNIFSYLFPKYSTNEAKKREVLSAASAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTL Q6PGA5_MOUSE Q6PGA5_MOUSE CCCGNIFSYLFPKYSTNEAKKREVLSAASAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTL Q8K4W8_MOUSE Q8K4W8_MOUSE CCCGNIFSYLFPKYSTNEAKKREVLSAASAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTL B4F6X6_XENTR B4F6X6_XENTR CCCGNIFSYLFPKYSTNEAKKREVLSAASAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTL A5PKR3_XENLA A5PKR3_XENLA CCCGNIFSYLFPKYNTNEAKKREVLSAASAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTL Q9YH11_XENLA Q9YH11_XENLA CCCGNIFSYLFPKYSTNEAKKREVLSAASAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTL A0PJS1_DANRE A0PJS1_DANRE CCCGNIFSYLFPKYSKNEAKKREVLSAASAAGVSVAFGAPIGGVFFSLEEVSYYFPLKTL A1A5X0_DANRE A1A5X0_DANRE CCCGNIFSYLFPKYSKNEAKKREVLSAASAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTL Q4T7N7_TETNG Q4T7N7_TETNG CCCGNIFSYLFPKYSKNEAKKREVLSAASAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTL Q9PUI6_OREMO Q9PUI6_OREMO CCCGNIFSYLFPKYSKNEAKKREVLSAASAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTL Q08BG8_DANRE Q08BG8_DANRE CCCGNLFCSLFSKYSKNEGKRREVLSAAAAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTL Q4SER7_TETNG Q4SER7_TETNG CCCGNLFCSLFSKYSKNEGKRREVLSAAAAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTL B0BMM3_XENTR B0BMM3_XENTR CCCGNLFSSLFSKYSKNEGKRREVLSAAAAVGVSVAFGAPIGGVLFSLEEVSYYFPLKTL Q4F894_BOVIN Q4F894_BOVIN CCCGNFFSSLFSKYSKNEGKRREVLSAAAAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTL B7Z5Z4_HUMAN B7Z5Z4_HUMAN CCCGNFFSSLFSKYSKNEGKRREVLSAAAAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTL Q4G0X3_HUMAN Q4G0X3_HUMAN CCCGNFFSSLFSKYSKNEGKRREVLSAAAAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTL A1L3U1_HUMAN A1L3U1_HUMAN CCCGNFFSSLFSKYSKNEGKRREVLSAAAAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTL CLCN4_HUMAN CLCN4_HUMAN CCCGNFFSSLFSKYSKNEGKRREVLSAAAAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTL CLCN4_RAT CLCN4_RAT CCCGNFFSSLFSKYSKNEGKRREVLSAAAAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTL Q56A19_RAT Q56A19_RAT CCCGNFFSSLFSKYSKNEGKRREVLSAAAAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTL CLCN4_MOUSE CLCN4_MOUSE CCCGNFFSSLFSKYSKNEGKRREVLSAAAAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTL Q3LRV6_MOUSE Q3LRV6_MOUSE CCCGNFFSSLFSKYSKNEGKRREVLSAAAAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTL Q8CBL5_MOUSE Q8CBL5_MOUSE CCCGNFFSSLFSKYSKNEGKRREVLSAAAAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTL Q99JZ2_MOUSE Q99JZ2_MOUSE CCCGNFFSSLFSKYSKNEGKRREVLSAAAAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTL Q2TAX6_MOUSE Q2TAX6_MOUSE CCCGNFFSSLFSKYSKNEGKRREVLSAAAAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTL MATCH .**.*.:. * ** **.*:**: CONSENSUS CCCGN?????F?KY??NE?K?REVLSAA?AAGVSVAFGAPIGGVLFSLEEVSYYFPLKTL

Q869D8_ASCSS Q869D8_ASCSS WRSVFCACVSAFILAHLNPFGPRHTVLFYVHYTQPWHLFELIPFAFLGMMGGLYSAAFIH Q4SXZ6_TETNG Q4SXZ6_TETNG WRSFFAALVAAFTLRSINPFGNSRLVLFYVEFHTPWHLVELLPFVLLGIFGGLWGALFIR Q9PUI5_OREMO Q9PUI5_OREMO WRSFFAALVAAFTLRSINPFGNSRLVLFYVEFHTPWHLVELAPFILLGIFGGLWGALFIK CLCN5_CAVPO CLCN5_CAVPO WRSFFAALVAAFTLRSINPFGNSRLVLFYVEFHTPWHLFELVPFILLGIFGGLWGALFIR CLCN5_PIG CLCN5_PIG WRSFFAALVAAFTLRSINPFGNSRLVLFYVEFHTPWHLFELVPFILLGIFGGLWGALFIR CLCN5_RABIT CLCN5_RABIT WRSFFAALVAAFTLRSINPFGNSRLVLFYVEFHTPWHLFELVPFILLGIFGGLWGALFIR CLCN5_RAT CLCN5_RAT WRSFFAALVAAFTLRSINPFGNSRLVLFYVEFHTPWHLFELVPFIVLGIFGGLWGALFIR Q8CI67_MOUSE Q8CI67_MOUSE WRSFFAALVAAFTLRSINPFGNSRLVLFYVEFHTPWHLFELVPFIVLGIFGGLWGALFIR Q3UL16_MOUSE Q3UL16_MOUSE WRSFFAALVAAFTLRSINPFGNSRLVLFYVEFHTPWHLFELVPFIVLGIFGGLWGALFIR B1ATV0_MOUSE B1ATV0_MOUSE WRSFFAALVAAFTLRSINPFGNSRLVLFYVEFHTPWHLFELVPFIVLGIFGGLWGALFIR CLCN5_MOUSE CLCN5_MOUSE WRSFFAALVAAFTLRSINPFGNSRLVLFYVEFHTPWHLFELVPFIVLGIFGGLWGALFIR Q8C6W8_MOUSE Q8C6W8_MOUSE WRSFFAALVAAFTLRSINPFGNSRLVLFYVEFHTPWHLFELVPFIVLGIFGGLWGALFIR B3KRR2_HUMAN B3KRR2_HUMAN WRSFFAALVAAFTLRSINPFGNSRLVLFYVEFHTPWHLFELVPFILLGIFGGLWGALFIR B3KPN6_HUMAN B3KPN6_HUMAN WRSFFAALVAAFTLRSINPFGNSRLVLFYVEFHTPWHLFELVPFILLGIFGGLWGALFIR A8K4H5_HUMAN A8K4H5_HUMAN WRSFFAALVAAFTLRSINPFGNSRLVLFYVEFHTPWHLFELVPFILLGIFGGLWGALFIR CLCN5_HUMAN CLCN5_HUMAN WRSFFAALVAAFTLRSINPFGNSRLVLFYVEFHTPWHLFELVPFILLGIFGGLWGALFIR CLCN5_PONAB CLCN5_PONAB WRSFFAALVAAFTLRSINPFGNSRLVLFYVEFHTPWHLFELVPFILLGIFGGLWGALFIR Q28C29_XENTR Q28C29_XENTR WRSFFAALVAAFTLRSINPFGNSRLVLFYVEFHAPWHLLELIPFILLGIFGGLWGAFFIR O13080_XENLA O13080_XENLA WRSFFAALVAAFTLRSINPFGNSRLVLFYVEFHAPWHLLELIPFILLGIFGGVWGAFFIR A2BD91_XENLA A2BD91_XENLA WRSFFAALVAAFTLRSINPFGNSRLVLFYVEFHAPWHLLELIPFILLGIFGGLWGAFFIR Q9PWK7_XENLA Q9PWK7_XENLA WRSFFAALVAAFTLRSINPFGNSRLVLFYVEFHAPWHLLELIPFILLGIFGGLWGAFFIR Q4LAL8_CANFA Q4LAL8_CANFA WRSFFAALVAAFVLRSINPFGNSRLVLFYVEYHTPWYLFELFPFILLGVFGGLWGAFFIR Q4LAL7_CANFA Q4LAL7_CANFA WRSFFAALVAAFVLRSINPFGNSRLVLFYVEYHTPWYLFELFPFILLGVFGGLWGAFFIR Q4R6L2_MACFA Q4R6L2_MACFA --------------------GNSRLVLFYVEYHTPWYLFELFPFILLGVFGGLWGAFFIR B7Z932_HUMAN B7Z932_HUMAN WRSFFAALVAAFVLRSINPFGNSRLVLFYVEYHTPWYLFELFPFILLGVFGGLWGAFFIR CLCN3_PONAB CLCN3_PONAB WRSFFAALVAAFVLRSINPFGNSRLVLFYVEYHTPWYLFELFPFILLGVFGGLWGAFFIR B3KXK0_HUMAN B3KXK0_HUMAN WRSFFAALVAAFVLRSINPFGNSRLVLFYVEYHTPWYLFELFPFILLGVFGGLWGAFFIR B9EGJ9_HUMAN B9EGJ9_HUMAN WRSFFAALVAAFVLRSINPFGNSRLVLFYVEYHTPWYLFELFPFILLGVFGGLWGAFFIR Q8K4W9_MOUSE Q8K4W9_MOUSE WRSFFAALVAAFVLRSINPFGNSRLVLFYVEYHTPWYLFELFPFILLGVFGGLWGAFFIR Q8K4W7_MOUSE Q8K4W7_MOUSE WRSFFAALVAAFVLRSINPFGNSRLVLFYVEYHTPWYLFELFPFILLGVFGGLWGAFFIR P97274_CAVPO P97274_CAVPO GRSFFAALVAAFVLRSINPFGNSRLVLFYVEYHTPWYLFELFPFILLGVFGGLWGAFFIR CLCN3_CAVPO CLCN3_CAVPO WRSFFAALVAAFVLRSINPFGNSRLVLFYVEYHTPWYLFELFPFILLGVFGGLWGAFFIR Q6PEV2_MOUSE Q6PEV2_MOUSE WRSFFAALVAAFVLRSINPFGNSRLVLFYVEYHTPWYLFELFPFILLGVFGGLWGAFFIR CLCN3_MOUSE CLCN3_MOUSE WRSFFAALVAAFVLRSINPFGNSRLVLFYVEYHTPWYLFELFPFILLGVFGGLWGAFFIR Q3TTK0_MOUSE Q3TTK0_MOUSE WRSFFAALVAAFVLRSINPFGNSRLVLFYVEYHTPWYLFELFPFILLGVFGGLWGAFFIR CLCN3_RAT CLCN3_RAT WRSFFAALVAAFVLRSINPFGNSRLVLFYVEYHTPWYLFELFPFILLGVFGGLWGAFFIR Q8K4X1_MOUSE Q8K4X1_MOUSE WRSFFAALVAAFVLRSINPFGNSRLVLFYVEYHTPWYLFELFPFILLGVFGGLWGAFFIR Q3TF45_MOUSE Q3TF45_MOUSE WRSFFAALVAAFVLRSINPFGNSRLVLFYVEYHTPWYLFELFPFILLGVFGGLWGAFFIR Q3UEX5_MOUSE Q3UEX5_MOUSE WRSFFAALVAAFVLRSINPFGNSRLVLFYVEYHTPWYLFELFPFILLGVFGGLWGAFFIR Q790S0_MOUSE Q790S0_MOUSE WRSFFAALVAAFVLRSINPFGNSRLVLFYVEYHTPWYLFELFPFILLGVFGGLWGAFFIR Q6PGA5_MOUSE Q6PGA5_MOUSE WRSFFAALVAAFVLRSINPFGNSRLVLFYVEYHTPWYLFELFPFILLGVFGGLWGAFFIR Q8K4W8_MOUSE Q8K4W8_MOUSE WRSFFAALVAAFVLRSINPFGNSRLVLFYVEYHTPWYLFELFPFILLGVFGGLWGAFFIR B4F6X6_XENTR B4F6X6_XENTR WRSFFAALVAAFVLRSINPFGNSRLVLFYVEYHTPWYLFELIPFILLGVFGGLWGAFFIR A5PKR3_XENLA A5PKR3_XENLA WRSFFAALVAAFVLRSINPFGNSRLVLFYVEYHTPWYLFELIPFILLGVFGGLWGAFFIR Q9YH11_XENLA Q9YH11_XENLA WRSFFAALVAAFVLRSINPFGNSRLVLFYVEYHTPWYLFELIPFILLGVFGGLWGAFFIR A0PJS1_DANRE A0PJS1_DANRE WRSFFAALVAAFVLRSINPFGNSRLVLFYVEYHTPWYLFELFPFILLGVFGGLWGAFFIR A1A5X0_DANRE A1A5X0_DANRE WRSFFAALVAAFVLRSINPFGNSRLVLFYVEYHTPWYLFELFPFILLGVFGGLWGAFFIR Q4T7N7_TETNG Q4T7N7_TETNG WRSFFAALVAAFVLRSINPFGNSRLVLFYVEYHTPWYLFELIPFILLGVFGGLWGAFFIR Q9PUI6_OREMO Q9PUI6_OREMO WRSFFAALVAAFVLRSINPFGNSRLVLFYVEYHTPWYLFELIPFILLGVFGGLWGAFFIK Q08BG8_DANRE Q08BG8_DANRE WRSFFAALVAAFTLRSINPFGNNRLVLFYVEYHTPWYMAELVPFILLGVFGGLWGTLFIR Q4SER7_TETNG Q4SER7_TETNG WRSFFAALVAAFTLRSINPFGNSRLVLFYVEYHTPWYMAELVPFILLGVFGGLWGTLFIR B0BMM3_XENTR B0BMM3_XENTR WRSFFAALVAAFTLRSINPFGNSRLVLFYVEYHTPWYMAELFPFILLGVFGGLWGTLFIR Q4F894_BOVIN Q4F894_BOVIN WRSFFAALVAAFTLRSINPFGNSRLVLFYVEYHTPWYMAELFPFILLGVFGGLWGTLFIR B7Z5Z4_HUMAN B7Z5Z4_HUMAN WRSFFAALVAAFTLRSINPFGNSRLVLFYVEYHTPWYMAELFPFILLGVFGGLWGTLFIR Q4G0X3_HUMAN Q4G0X3_HUMAN WRSFFAALVAAFTLRSINPFGNSRLVLFYVEYHTPWYMAELFPFILLGVFGGLWGTLFIR A1L3U1_HUMAN A1L3U1_HUMAN WRSFFAALVAAFTLRSINPFGNSRLVLFYVEYHTPWYMAELFPFILLGVFGGLWGTLFIR CLCN4_HUMAN CLCN4_HUMAN WRSFFAALVAAFTLRSINPFGNSRLVLFYVEYHTPWYMAELFPFILLGVFGGLWGTLFIR CLCN4_RAT CLCN4_RAT WRSFFAALVAAFTLRSINPFGNSRLVLFYVEYHTPWYMAELFPFILLGVFGGLWGTVFTR Q56A19_RAT Q56A19_RAT WRSFFAALVAAFTLRSINPFGNSRLVLFYVEYHTPWYMAELFPFILLGVFGGLWGTVFTR CLCN4_MOUSE CLCN4_MOUSE WRSFFRALVAAFTLRSINPFGNSRLVLFYVEYHTPWYMAELFPFILLGVFGGLWGTLFTR Q3LRV6_MOUSE Q3LRV6_MOUSE WRSFFAALVAAFTLRSINPFGNSRLVLFYVEYHTPWYMAELFPFILLGVFGGLWGTLFTR Q8CBL5_MOUSE Q8CBL5_MOUSE WRSFFAALVAAFTLRSINPFGNSRLVLFYVEYHTPWYMAELFPFILLGVFGGLWGTLFTR Q99JZ2_MOUSE Q99JZ2_MOUSE WRSFFAALVAAFTLRSINPFGNSRLVLFYVEYHTPW------------------------ Q2TAX6_MOUSE Q2TAX6_MOUSE WRSFFAALVAAFTLRSINPFGNSRLVLFYVEYHTPWYMAELFPFILLGVFGGLWGTLFTR MATCH * : *****.: ** CONSENSUS WRSFFAALVAAF?LRSINPFGNSRLVLFYVE?HTPW???EL?PFILLG?FGGLWG??FIR

Q869D8_ASCSS Q869D8_ASCSS ANLAWCKFRKNSRLGDYPILEVMVVTLITAVAGYQNPYTRIGATPMIYELVKECHPWETN Q4SXZ6_TETNG Q4SXZ6_TETNG ANIAWCRIRKTTRLGRYPIVEVLAVTAVTALVAYPNSYTRMSGAELISELFNDCSLLDSS Q9PUI5_OREMO Q9PUI5_OREMO ANIAWCRLRKTTCLGHYPVIEVLVVAALTALLSYPNSYTRMSGSELISELFNDCSLLDSS CLCN5_CAVPO CLCN5_CAVPO TNIAWCRKRKTTQLGKYPVIEVLIVTAITAILAFPNEYTRMSTSELISELFNDCGLLDSS CLCN5_PIG CLCN5_PIG TNIAWCRKRKTTQLGKYPVIEVLVVTAITAILAFPNEYTRMSTSELISELFNDCGLLDSS CLCN5_RABIT CLCN5_RABIT TNIAWCRKRKTTQLGKYPVIEVLIVTAITAILAFPNEYTRMSTSELISELFNDCGLLDSS CLCN5_RAT CLCN5_RAT TNIAWCRKRKTTQLGKYPVVEVLIVTAITAILAFPNEYTRMSTSELISELFNDCGLLDSS Q8CI67_MOUSE Q8CI67_MOUSE TNIAWCRKRKTTQLGKYPVVEVLIVTAITAILAFPNEYTRMSTSELISELFNDCGLLDSS Q3UL16_MOUSE Q3UL16_MOUSE TNIAWCRKRKTTQLGKYPVVEVLIVTAITAILAFPNEYTRMSTSELISELFNDCGLLDSS B1ATV0_MOUSE B1ATV0_MOUSE TNIAWCRKRKTTQLGKYPVVEVLIVTAITAILAFPNEYTRMSTSELISELFNDCGLLDSS CLCN5_MOUSE CLCN5_MOUSE TNIAWCRKRKTTQLGKYPVVEVLIVTAITAILAFPNEYTRMSTSELISELFNDCGLLDSS Q8C6W8_MOUSE Q8C6W8_MOUSE TNIAWCRKRKTTQLGKYPVVEVLIVTAITAILAFPNEYTRMSTSELISELFNDCGLLDSS B3KRR2_HUMAN B3KRR2_HUMAN TNIAWCRKRKTTQLGKYPVIEVLVVTAITAILAFPNEYTRMSTSELISELFNDYGLLDSS B3KPN6_HUMAN B3KPN6_HUMAN TNIAWCRKRKTTQLGKYPVIEVLVVTAITAILAFPNEYTRMSTSELISELFNDCGLLDSS A8K4H5_HUMAN A8K4H5_HUMAN TNIAWCRKRKTTQLGKYPVIEVLVVTAITAILAFPNEYTRMSTSELISELFNDCGLLDSS CLCN5_HUMAN CLCN5_HUMAN TNIAWCRKRKTTQLGKYPVIEVLVVTAITAILAFPNEYTRMSTSELISELFNDCGLLDSS CLCN5_PONAB CLCN5_PONAB TNIAWCRKRKTTQLGKYPVIEVLVVTAITAILAFPNEYTRMSTSELISELFNDCGLLDSS Q28C29_XENTR Q28C29_XENTR GNIAWCQRRKTTKLGRYPVAEVLVVTAITAVLAFPNDYTRMSSSEMISELFNDCGLLDSS O13080_XENLA O13080_XENLA ANIAWCHRRKTTKLGRYPVAEVLMVTAITAILAFPNDYTRMSSSEMISELFNDCGLLDSS A2BD91_XENLA A2BD91_XENLA ANIAWCHRRKTTKLGRYPVAEVLMVTAITAILAFPNDYTRMSSSEMISELFNDCGLLDSS Q9PWK7_XENLA Q9PWK7_XENLA ANIAWCHRRKTTKLGRYPVAEVLMVTAITAILAFPNDYTRMSSSEMISELFNDCGLLDSS Q4LAL8_CANFA Q4LAL8_CANFA ANIAWCRRRKSTRFGKYPVLEVIVVAAITAVIAFPNPYTRLNTSELIKELFTDCGPLESS Q4LAL7_CANFA Q4LAL7_CANFA ANIAWCRRRKSTRFGKYPVLEVIVVAAITAVIAFPNPYTRLNTSELIKELFTDCGPLESS Q4R6L2_MACFA Q4R6L2_MACFA ANIAWCRRRNSTKFGKCPVLEVIIVAAITAVIAFPNPYTRLNTSELIKELFTDCGPLESS B7Z932_HUMAN B7Z932_HUMAN ANIAWCRRRKSTKFGKYPVLEVIIVAAITAVIAFPNPYTRLNTSELIKELFTDCGPLESS CLCN3_PONAB CLCN3_PONAB ANIAWCRRRKSTKFGKYPVLEVIIVA