Alignment of the gene Family HBG051346 of HOVERGEN

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Threshold: 50% 80% 100%
Size: Bigger Smaller Normal
Isoforms are ON
DGKK_HUMAN DGKK_HUMAN DRGAAAAQGTAPPQDGEQPAESPEPPPPWPPPPPPPAPPPAPPLLSEASPEPIPEPCPEL A2AEP1_MOUSE A2AEP1_MOUSE ------------------------------------------------------------ Q6DIC8_MOUSE Q6DIC8_MOUSE ------------------MERAPESWPEPTPESCLRMSPALHLLQVVPGEKSGTAS---- Q4SB53_TETNG Q4SB53_TETNG ------------------------------------------------------------ Q4SB55_TETNG Q4SB55_TETNG -----------------------------MAEAGGPESAAARCPDESSDSEPEQEP---- Q6A0B7_MOUSE Q6A0B7_MOUSE ------------------------------------------------------------ A6QPL5_BOVIN A6QPL5_BOVIN -----------------------MAAAAGAPQPGPPQPPPPPPPEESSDSEPEAEP---- DGKD_HUMAN DGKD_HUMAN -----------------------MAAAAGAPPPGPPQPPPPPPPEESSDSEPEAEP---- Q53SE4_HUMAN Q53SE4_HUMAN ------------------------------------------------------------ Q4T7K6_TETNG Q4T7K6_TETNG --------------------------------------MAPLLLRCEGEGQEDGDP---- B8JI39_DANRE B8JI39_DANRE ------------------------------------------------------------ B0R0T0_DANRE B0R0T0_DANRE ------------------PPQEPEKAAASASGVPAVGAVGGSGPVVDESSDSEGEQ---- B4DYW1_HUMAN B4DYW1_HUMAN ------------------------------------------------------------ A8K0I1_HUMAN A8K0I1_HUMAN ----------MAGAGGQHHPPGAAGGAAAGAGAAVTSAAASAGP-GEDSSDSEAEQ---- B4DZ34_HUMAN B4DZ34_HUMAN ------------------------------------------------------------ DGKH_HUMAN DGKH_HUMAN ----------MAGAGGQHHPPGAAGGAAAGAGAAVTSAAASAGP-GEDSSDSEAEQ---- A0JP53_MOUSE A0JP53_MOUSE ------------------------------------------------------------ DGKH_MESAU DGKH_MESAU ----------MAGAGYQHHPPGGAAVGTSAV------SPTAAGP-GEDSSDSEAEQ---- MATCH CONSENSUS ????????????????????????????????????????????????????????????

DGKK_HUMAN DGKK_HUMAN APGPCPEATSESATELYTEPTPEPATEPASEPAPEPATEPAPEPATEPAPEPAPEPATES A2AEP1_MOUSE A2AEP1_MOUSE ------------------------------------------------------------ Q6DIC8_MOUSE Q6DIC8_MOUSE ------------------------------------------------------------ Q4SB53_TETNG Q4SB53_TETNG ------------------------------------------------------------ Q4SB55_TETNG Q4SB55_TETNG ------------------------------------------------------------ Q6A0B7_MOUSE Q6A0B7_MOUSE ------------------------------------------------------------ A6QPL5_BOVIN A6QPL5_BOVIN ------------------------------------------------------------ DGKD_HUMAN DGKD_HUMAN ------------------------------------------------------------ Q53SE4_HUMAN Q53SE4_HUMAN ------------------------------------------------------------ Q4T7K6_TETNG Q4T7K6_TETNG ------------------------------------------------------------ B8JI39_DANRE B8JI39_DANRE ------------------------------------------------------------ B0R0T0_DANRE B0R0T0_DANRE ------------------------------------------------------------ B4DYW1_HUMAN B4DYW1_HUMAN ------------------------------------------------------------ A8K0I1_HUMAN A8K0I1_HUMAN ------------------------------------------------------------ B4DZ34_HUMAN B4DZ34_HUMAN ------------------------------------------------------------ DGKH_HUMAN DGKH_HUMAN ------------------------------------------------------------ A0JP53_MOUSE A0JP53_MOUSE ------------------------------------------------------------ DGKH_MESAU DGKH_MESAU ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

DGKK_HUMAN DGKK_HUMAN APEPTPEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPSPAPCL A2AEP1_MOUSE A2AEP1_MOUSE ------------------------------------------------------------ Q6DIC8_MOUSE Q6DIC8_MOUSE ------------------------------------------------------------ Q4SB53_TETNG Q4SB53_TETNG ------------------------------------------------------------ Q4SB55_TETNG Q4SB55_TETNG ------------------------------------------------------------ Q6A0B7_MOUSE Q6A0B7_MOUSE ------------------------------------------------------------ A6QPL5_BOVIN A6QPL5_BOVIN ------------------------------------------------------------ DGKD_HUMAN DGKD_HUMAN ------------------------------------------------------------ Q53SE4_HUMAN Q53SE4_HUMAN ------------------------------------------------------------ Q4T7K6_TETNG Q4T7K6_TETNG ------------------------------------------------------------ B8JI39_DANRE B8JI39_DANRE ------------------------------------------------------------ B0R0T0_DANRE B0R0T0_DANRE ------------------------------------------------------------ B4DYW1_HUMAN B4DYW1_HUMAN ------------------------------------------------------------ A8K0I1_HUMAN A8K0I1_HUMAN ------------------------------------------------------------ B4DZ34_HUMAN B4DZ34_HUMAN ------------------------------------------------------------ DGKH_HUMAN DGKH_HUMAN ------------------------------------------------------------ A0JP53_MOUSE A0JP53_MOUSE ------------------------------------------------------------ DGKH_MESAU DGKH_MESAU ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

DGKK_HUMAN DGKK_HUMAN LQCPVDTRERGLKTSPSPSPSPSPRTPMSWSRIKKILKEGPMLKNCNSFKRWKLRYFLVQ A2AEP1_MOUSE A2AEP1_MOUSE ----------------------------------KILKEGPLLKNCNSFRRWKLRYCLVQ Q6DIC8_MOUSE Q6DIC8_MOUSE ---------------PVLLPLPSPKPPITWSRIKKILKEGPLLKNCNSFRRWKLRYCLVQ Q4SB53_TETNG Q4SB53_TETNG ------------------------------------------------------------ Q4SB55_TETNG Q4SB55_TETNG ---------------GTPQKLIRKVSTSGQIRSKAAVWDISQCDTQPGRVLGDARYSCTR Q6A0B7_MOUSE Q6A0B7_MOUSE ------------------------------------------------------------ A6QPL5_BOVIN A6QPL5_BOVIN ---------------GSPQKLIRKVSTSGQIRQKTVIKEGMLTKQNNSFQRSKRRYFKLR DGKD_HUMAN DGKD_HUMAN ---------------GSPQKLIRKVSTSGQIRQKTIIKEGMLTKQNNSFQRSKRRYFKLR Q53SE4_HUMAN Q53SE4_HUMAN ------------------------------------------------------------ Q4T7K6_TETNG Q4T7K6_TETNG ---------------------LEAKAQETHLEGEKSVKEGILLKQTSSFQRWKRRYFKLR B8JI39_DANRE B8JI39_DANRE ------------------------------------VKEGLLLKQTSSFQRWKRRYFKLR B0R0T0_DANRE B0R0T0_DANRE ---------------EGPQKLIRKVSTSGQIRSKTSVKEGLLLKQTSSFQRWKKRYFKLR B4DYW1_HUMAN B4DYW1_HUMAN ------------------------------------------------------------ A8K0I1_HUMAN A8K0I1_HUMAN ---------------EGPQKLIRKVSTSGQIRTKTSIKEGQLLKQTSSFQRWKKRYFKLR B4DZ34_HUMAN B4DZ34_HUMAN ------------------------------------------------------------ DGKH_HUMAN DGKH_HUMAN ---------------EGPQKLIRKVSTSGQIRTKTSIKEGQLLKQTSSFQRWKKRYFKLR A0JP53_MOUSE A0JP53_MOUSE ------------------------------------------------------------ DGKH_MESAU DGKH_MESAU ---------------GGPQKLIRKVSTSGQIRTKTSIKEGQLLKQTSSFQRWKKRYFKLR MATCH CONSENSUS ????????????????????????????????????????????????????????????

DGKK_HUMAN DGKK_HUMAN GQKLYFAHHPA----------------------FAHFETIDLSQATVAESSCRNLCHSFC A2AEP1_MOUSE A2AEP1_MOUSE GQKLHFAHHPS----------------------FAHFETIDLSQVVLAESSCRNLCHGFC Q6DIC8_MOUSE Q6DIC8_MOUSE GQKLHFAHHPS----------------------FAHFETIDLSQVVLAESSCRNLCHGFC Q4SB53_TETNG Q4SB53_TETNG ------------------------------------------------------------ Q4SB55_TETNG Q4SB55_TETNG GKAGNNGAFRGQARGQRPAAV----------LKSIIFDEVDLTDASVAESSTKNVNNSFT Q6A0B7_MOUSE Q6A0B7_MOUSE ------------------------------------------------------------ A6QPL5_BOVIN A6QPL5_BOVIN GRTLYYAKTAK----------------------SIIFDEVDLTDASVAESSTKNVNNSFT DGKD_HUMAN DGKD_HUMAN GRTLYYAKTAK----------------------SIIFDEVDLTDASVAESSTKNVNNSFT Q53SE4_HUMAN Q53SE4_HUMAN ------------------------------------------------------------ Q4T7K6_TETNG Q4T7K6_TETNG GRTLYYAKDCKVGKVAAPAWLAGLTRVRSLRLQSLIFDEVDLSDASVAETSTKNINNSFT B8JI39_DANRE B8JI39_DANRE GRTLYYAKDSK----------------------SLIFDEVDLSDASVAETSTKNINNSFT B0R0T0_DANRE B0R0T0_DANRE GRTLYYAKDAK----------------------SLIFDEVDLSDASVAESSTKNINNSFT B4DYW1_HUMAN B4DYW1_HUMAN ------------------------------------------------------------ A8K0I1_HUMAN A8K0I1_HUMAN GRTLYYAKDSK----------------------SLIFDEVDLSDASVAEASTKNANNSFT B4DZ34_HUMAN B4DZ34_HUMAN ------------------------------------------------------------ DGKH_HUMAN DGKH_HUMAN GRTLYYAKDSK----------------------SLIFDEVDLSDASVAEASTKNANNSFT A0JP53_MOUSE A0JP53_MOUSE ------------------------------------------------------------ DGKH_MESAU DGKH_MESAU GRTLYYAKDSK----------------------SLIFDEVDLSDASVAEASTKNANNSFT MATCH CONSENSUS ????????????????????????????????????????????????????????????

DGKK_HUMAN DGKK_HUMAN V-------------------------------ITPQRKITLAAPNRKDMEEWINIIKTIQ A2AEP1_MOUSE A2AEP1_MOUSE V-------------------------------ITPHRKVSLVAPTRQDMEEWINIIKTVQ Q6DIC8_MOUSE Q6DIC8_MOUSE V-------------------------------ITPHRKVSLVAPTRQDMEEWINIIKTVQ Q4SB53_TETNG Q4SB53_TETNG ------------------------------------------------------------ Q4SB55_TETNG Q4SB55_TETNG VRPRPLPVWVRPSTDAFRAESLTGSNGSQSVFALGYVRLILCADNRKEMEEWMAALRSVQ Q6A0B7_MOUSE Q6A0B7_MOUSE ------------------------------------------------------------ A6QPL5_BOVIN A6QPL5_BOVIN V-------------------------------ITPCRKLILCADNRKEMEDWIAALKTVQ DGKD_HUMAN DGKD_HUMAN V-------------------------------ITPCRKLILCADNRKEMEDWIAALKTVQ Q53SE4_HUMAN Q53SE4_HUMAN V-------------------------------ITPCRKLILCADNRKEMEDWIAALKTVQ Q4T7K6_TETNG Q4T7K6_TETNG V-------------------------------ITPFRKLMLCAESRKEMEDWIGALRSVQ B8JI39_DANRE B8JI39_DANRE V-------------------------------ITPFRKLMLCAESRKEMEDWISALKSVQ B0R0T0_DANRE B0R0T0_DANRE V-------------------------------ITPFRRLILCAENRKEMEDWISSLKSVQ B4DYW1_HUMAN B4DYW1_HUMAN ------------------------------------------------------------ A8K0I1_HUMAN A8K0I1_HUMAN I-------------------------------ITPFRRLMLCAENRKEMEDWISSLKSVQ B4DZ34_HUMAN B4DZ34_HUMAN ---------------------------------------MLCAENRKEMEDWISSLKSVQ DGKH_HUMAN DGKH_HUMAN I-------------------------------ITPFRRLMLCAENRKEMEDWISSLKSVQ A0JP53_MOUSE A0JP53_MOUSE ---------------------------------------MLCAENRKEMEVWISSLKSVQ DGKH_MESAU DGKH_MESAU I-------------------------------ITPFRRLMLCAENRKEMEDWISSLKSVQ MATCH CONSENSUS ????????????????????????????????????????L?A??R??ME?W???????Q

DGKK_HUMAN DGKK_HUMAN QGEIYKIPAAENNPFLVGMHCWYSSYSHRTQHCNVCRESIPALSRDAIICEVCKVKSHRL A2AEP1_MOUSE A2AEP1_MOUSE QGEIRQIPAAENNPFLVGMHYWYSSSNPRSHFCNVCRENIPALSRDAVTCEVCQVKSHKF Q6DIC8_MOUSE Q6DIC8_MOUSE QGEIRQIPAAENNPFLVGMHYWYSSSNPRSHFCNVCRENIPALSRDAVTCEVCQVKSHKF Q4SB53_TETNG Q4SB53_TETNG ------------------------------------------------------------ Q4SB55_TETNG Q4SB55_TETNG NRQNYE-STQYSMDHFSGMHNWYACSHARPTYCNVCREALSGVTSHGLSCEA-------- Q6A0B7_MOUSE Q6A0B7_MOUSE -------------------------------------EVLSGVTSHGLSCEVCKFKAHKR A6QPL5_BOVIN A6QPL5_BOVIN SREHFE-PTQYSMDHFSGTHNWYACSHARPTYCNVCREALSGVTSHGLSCEVCKFKAHKR DGKD_HUMAN DGKD_HUMAN NREHFE-PTQYSMDHFSGMHNWYACSHARPTYCNVCREALSGVTSHGLSCEVCKFKAHKR Q53SE4_HUMAN Q53SE4_HUMAN NREHFE-PTQYSMDHFSGMHNWYACSHARPTYCNVCREALSGVTSHGLSCEVCKFKAHKR Q4T7K6_TETNG Q4T7K6_TETNG KWETYE-ASQFNMEHFSGMHNWYACSHARPTFCNVCREALPGVTSHGLSCEVCKFKAHKR B8JI39_DANRE B8JI39_DANRE KWETYE-ASQFNMEHFSGMHNWYACSHARPTFCNVCREALPGVTSHGLSCEVCKFKAHKR B0R0T0_DANRE B0R0T0_DANRE SREHYE-TAQFNVEHFSGMHNWYACSHARPTFCNVCRDSLSGVTSHGLSCEVCKFKAHKR B4DYW1_HUMAN B4DYW1_HUMAN --------------------MW--------NISQGCTTGTPAPTPDPPSVT--------- A8K0I1_HUMAN A8K0I1_HUMAN TREPYE-VAQFNVEHFSGMHNWYACSHARPTFCNVCRESLSGVTSHGLSCEVCKFKAHKR B4DZ34_HUMAN B4DZ34_HUMAN TREPYE-VAQFNVEHFSGMHNWYACSHARPTFCNVCRESLSGVTSHGLSCEVCKFKAHKR DGKH_HUMAN DGKH_HUMAN TREPYE-VAQFNVEHFSGMHNWYACSHARPTFCNVCRESLSGVTSHGLSCEVCKFKAHKR A0JP53_MOUSE A0JP53_MOUSE SREPYE-VAQFNVEHFSGMHNWYACSHARPTFCNVCRESLSGVTSHGLSCEVCKFKAHKR DGKH_MESAU DGKH_MESAU SREPYE-VAQFNVEHFSGMHNWYACSHARPTFCNVCRESLSGVTSHGLSCEVCKFKAHKR MATCH CONSENSUS ?????????????????G?H?WY?????R???CNVCRE???????????CEVC??K?H??

DGKK_HUMAN DGKK_HUMAN CALRASKDCKWNTL-SITDDLLLPADEVN-------------------------MPHQWV A2AEP1_MOUSE A2AEP1_MOUSE CALRANKDCKWNTL-SVTDDLLLPADEIQT------------------------MPHQWV Q6DIC8_MOUSE Q6DIC8_MOUSE CALRANKDCKWNTL-SVTDDLLLPADEIQT------------------------MPHQWV Q4SB53_TETNG Q4SB53_TETNG ------------------------------------------------------------ Q4SB55_TETNG Q4SB55_TETNG CAVRATNNCKWTTLASIGKDIIEDEDGVS-------------------------MPHQWL Q6A0B7_MOUSE Q6A0B7_MOUSE CAVRATSNCKWTTLASIGKDIIEDEDGIA-------------------------MPHQWL A6QPL5_BOVIN A6QPL5_BOVIN CAVRATSNCKWTTLASIGKDIIEDEDGIA-------------------------MPHQWL DGKD_HUMAN DGKD_HUMAN CAVRATNNCKWTTLASIGKDIIEDADGIA-------------------------MPHQWL Q53SE4_HUMAN Q53SE4_HUMAN CAVRATNNCKWTTLASIGKDIIEDADGIA-------------------------MPHQWL Q4T7K6_TETNG Q4T7K6_TETNG CAVRSTNNCKWTTLASIGGDIMEDEDGVSGEGWGGRGGGGADTCVCVCVCVQVFMPHQWL B8JI39_DANRE B8JI39_DANRE CAVRSTNTCKWTTLASIGNDIIEDEDGVS-------------------------MPHQWL B0R0T0_DANRE B0R0T0_DANRE CAVRATNNCKWTTLASIGKDIIEDEDGIA-------------------------MPHQWL B4DYW1_HUMAN B4DYW1_HUMAN CAER----------------VFLESPPMA------------------------------- A8K0I1_HUMAN A8K0I1_HUMAN CAVRATNNCKWTTLASIGKDIIEDEDGVA-------------------------MPHQWL B4DZ34_HUMAN B4DZ34_HUMAN CAVRATNNCKWTTLASIGKDIIEDEDGVA-------------------------MPHQWL DGKH_HUMAN DGKH_HUMAN CAVRATNNCKWTTLASIGKDIIEDEDGVA-------------------------MPHQWL A0JP53_MOUSE A0JP53_MOUSE CAVRATNNCKWTTLASIGKDIIEDEDGVA-------------------------MPHQWL DGKH_MESAU DGKH_MESAU CAVRATNNCKWTTLASIGKDIIEDEDGVA-------------------------MPHQWL MATCH CONSENSUS CA?R????CKW?TL?S???D?????D????????????????????????????MPHQW?

DGKK_HUMAN DGKK_HUMAN EGNMPVSSQCAVCHESCGSYQRLQDFRCLWCNSTVHDDCRRRFSKECCFRSHRSSVIPPT A2AEP1_MOUSE A2AEP1_MOUSE EGNIPAGSQCVVCHKSCGSHHRLQDFRCLWCGSTVHGACQKRFSKECSFGSRRSSIVPPT Q6DIC8_MOUSE Q6DIC8_MOUSE EGNIPAGSQCVVCHKSCGSHHRLQDFRCLWCGSTVHGACQKRFSKECSFGSRRSSIVPPT Q4SB53_TETNG Q4SB53_TETNG ------------------------------------------------------------ Q4SB55_TETNG Q4SB55_TETNG EGNLPVSAKCHVCDKTCGSVLRLQDWRCLWCKAM-------------------------- Q6A0B7_MOUSE Q6A0B7_MOUSE EGNLPVSAKCIVCDKTCGSVLRLQDWRCLWCKAMVHTSCKESLVMKCPLGLCKVSVIPPT A6QPL5_BOVIN A6QPL5_BOVIN EGNLPVSAKCTVCDKTCGSVLRLQDWRCLWCKAMVHTACKDSLVTKCPLGLCKVSVIPPT DGKD_HUMAN DGKD_HUMAN EGNLPVSAKCTVCDKTCGSVLRLQDWRCLWCKAMVHTSCKESLLTKCPLGLCKVSVIPPT Q53SE4_HUMAN Q53SE4_HUMAN EGNLPVSAKCTVCDKTCGSVLRLQDWRCLWCKAMVHTSCKESLLTKCPLGLCKVSVIPPT Q4T7K6_TETNG Q4T7K6_TETNG EGNLPVSARCVVCDRNCGSVRRLQDWRCLWCKAIVHSSCKDQTGKVCPLGQCRVSIIPPT B8JI39_DANRE B8JI39_DANRE EGNLPVSAKCVVCDRNCGSVRRLQDWRCLWCKAIVHNSCKEQLGKVCPLGQCKVSIIPPT B0R0T0_DANRE B0R0T0_DANRE EGNLPVSAKCAVCDKTCGSVLRLQDWRCLWCKAMVHTACMDLYPRKCPLGQCKVSIIPPT B4DYW1_HUMAN B4DYW1_HUMAN ------------------------------CPAKVHTACKDLYHPICPLGQCKVSIIPPI A8K0I1_HUMAN A8K0I1_HUMAN EGNLPVSAKCAVCDKTCGSVLRLQDWKCLWCKTMVHTACKDLYHPICPLGQCKVSIIPPI B4DZ34_HUMAN B4DZ34_HUMAN EGNLPVSAKCAVCDKTCGSVLRLQDWKCLWCKTMVHTACKDLYHPICPLGQCKVSIIPPI DGKH_HUMAN DGKH_HUMAN EGNLPVSAKCAVCDKTCGSVLRLQDWKCLWCKTMVHTACKDLYHPICPLGQCKVSIIPPI A0JP53_MOUSE A0JP53_MOUSE EGNLPVSAKCAVCDKTCGSVLRLQDWKCLWCKTMVHTACKDVYHPVCPLGQCKVSIIPPI DGKH_MESAU DGKH_MESAU EGNLPVSAKCAVCDKTCGSVLRLQDWKCLWCKAMVHTACKDLYHPVCPLGQCKVSIIPPI MATCH CONSENSUS EGN?P????C?VC???CGS??RLQD??CLWC???VH??C???????C??G????S??PP?

DGKK_HUMAN DGKK_HUMAN ALSDPKGDGQLVVSSDF---WNLDWSSACSCPLLIFINSKSGDHQGIVFLRKFKQYLNPS A2AEP1_MOUSE A2AEP1_MOUSE ALSDPRGDGQLVVSPDF---WNLDWPLTCSCPLLIFINSKSGDHQGIIFLRKFKQYLNPS Q6DIC8_MOUSE Q6DIC8_MOUSE ALSDPRGDGQLVVSPDF---WNLDWPLTCSCPLLIFINSKSGDHQGIIFLRKFKQYLNPS Q4SB53_TETNG Q4SB53_TETNG -----------------------------TSPLLVFVNSKSGDNQGVKFLRRFKQLLNPA Q4SB55_TETNG Q4SB55_TETNG ----------------------------------------SGDNQGVKFLRRFKQLLNPA Q6A0B7_MOUSE Q6A0B7_MOUSE ALNSIDSDG-------F---WKATCPPSCTSPLLVFVNSKSGDNQGVKFLRRFKQLLNPA A6QPL5_BOVIN A6QPL5_BOVIN ALNSIDSDG-------F---WKATCPPSCTSPLLVFVNSKSGDNQGVKFLRRFKQLLNPA DGKD_HUMAN DGKD_HUMAN ALNSIDSDG-------F---WKASCPPSCTSPLLVFVNSKSGDNQGVKFLRRFKQLLNPA Q53SE4_HUMAN Q53SE4_HUMAN ALNSIDSDG-------F---WKASCPPSCTSPLLVFVNSKSGDNQGVKFLRRFKQLLNPA Q4T7K6_TETNG Q4T7K6_TETNG ALNSIDSDASRAPALTFQASGKATS-GSCSSPLLVLVNSKSGDNQGVKFLRKFKQLLNPA B8JI39_DANRE B8JI39_DANRE ALNSIDSDG-------F---WKATS-PSCSSPLLVLVNSKSGDNQGVKFLRRFKQLLNPA B0R0T0_DANRE B0R0T0_DANRE ALNSIDSDG-------F---WKATCPPSCASPLLVFVNSKSGDNQGVKFLRRFKQLLNPA B4DYW1_HUMAN B4DYW1_HUMAN ALNSTDSDG-------F---CRATF-SFCVSPLLVFVSSKSGDNQGVKFLRRFKQLLNPA A8K0I1_HUMAN A8K0I1_HUMAN ALNSTDSDG-------F---CRATF-SFCVSPLLVFVNSKSGDNQGVKFLRRFKQLLNPA B4DZ34_HUMAN B4DZ34_HUMAN ALNSTDSDG-------F---CRATF-SFCVSPLLVFVNSKSGDNQGVKFLRRFKQLLNPA DGKH_HUMAN DGKH_HUMAN ALNSTDSDG-------F---CRATF-SFCVSPLLVFVNSKSGDNQGVKFLRRFKQLLNPA A0JP53_MOUSE A0JP53_MOUSE ALNSTDSDG-------F---CRATF-SFCVSPLLVFVNSKSGDNQGVKFLRRFKQLLNPA DGKH_MESAU DGKH_MESAU ALNSTDSDG-------F---CRATF-SFCVSPLLVFVNSKSGDNQGVKFLRRFKQLLNPA MATCH ***:**: ***:*** ***: CONSENSUS AL?????DG???????F???????????C??PLL?F?NSKSGDNQGVKFLR?FKQLLNPA

DGKK_HUMAN DGKK_HUMAN QVFDLLKGGPEAGLSMFKNFARFRILVCGGDGSVSWVLSLIDAFGLHEK----------- A2AEP1_MOUSE A2AEP1_MOUSE QVFDLAKGGPEAGIAMFKNFARFRVLVCGGDGSVSWVLSTIDAYGLHDR----------- Q6DIC8_MOUSE Q6DIC8_MOUSE QVFDLAKGGPEAGIAMFKNFARFRVLVCGGDGSVSWVLSTIDAYGLHDR----------- Q4SB53_TETNG Q4SB53_TETNG QVFDLMNGGPHLGLRLFQKFDTFRILVCGGDGSVGWVLSEIDALTLHKQVRLCRRADGPP Q4SB55_TETNG Q4SB55_TETNG QVFDLMNGGPHLGLRLFQKFDTFRILVCGGDGSVGWVLSEIDALTLHKQVRLCRRSRRAA Q6A0B7_MOUSE Q6A0B7_MOUSE QVFDLMNGGPHLGLRLFQKFDTFRILVCGGDGSVGWVLSEIDSLNLHKQ----------- A6QPL5_BOVIN A6QPL5_BOVIN QVFDLMNGGPHLGLRLFQKFDTFRILVCGGDGSVGWVLSEIDSLNLHKQ----------- DGKD_HUMAN DGKD_HUMAN QVFDLMNGGPHLGLRLFQKFDTFRILVCGGDGSVGWVLSEIDSLNLHKQ----------- Q53SE4_HUMAN Q53SE4_HUMAN QVFDLMNGGPHLGLRLFQKFDTFRILVCGGDGSVGWVLSEIDSLNLHKQ----------- Q4T7K6_TETNG Q4T7K6_TETNG QVFDLMNGGPELGLRLFQKFVTFRILVCGGDGSVGWVLSELDKLRLHKQ----------- B8JI39_DANRE B8JI39_DANRE QVFDLMNGGPQLGLRLFQKFETFRTLVCGGDGSVGWVLSELDKLSLHKQ----------- B0R0T0_DANRE B0R0T0_DANRE QVFDLVNGGPHLGLRLFQKFDNFRILVCGGDGSVGWVLSEIDKLNLHKQ----------- B4DYW1_HUMAN B4DYW1_HUMAN QVFDLMNGGPHLGLRLFQKFDNFRILVCGGDGSVGWVLSEIDKLNLNKQ----------- A8K0I1_HUMAN A8K0I1_HUMAN QVFDLMNGGPHLGLRLFQKFDNFRILVCGGDGSVGWVLSEIDKLNLNKQ----------- B4DZ34_HUMAN B4DZ34_HUMAN QVFDLMNGGPHLGLRLFQKFDNFRILVCGGDGSVGWVLSEIDKLNLNKQ----------- DGKH_HUMAN DGKH_HUMAN QVFDLMNGGPHLGLRLFQKFDNFRILVCGGDGSVGWVLSEIDKLNLNKQ----------- A0JP53_MOUSE A0JP53_MOUSE QVFDLMNGGPYLGLRLFQKFDNFRILVCGGDGSVGWVLSEIDKLNLHKQ----------- DGKH_MESAU DGKH_MESAU QVFDLMNGGPHLGLRLFQKFDNFRILVCGGDGSVGWVLSEIDKLNLNKQ----------- MATCH ***** :*** *: :*::* ** *********.**** :* *:.: CONSENSUS QVFDL?NGGP?LGLRLFQKF??FRILVCGGDGSVGWVLSEID?L?L?KQ???????????

DGKK_HUMAN DGKK_HUMAN --------------CQLAVIPLGTGNDLARVLGWGAFWNKSKSP--LDI-----LNRVEQ A2AEP1_MOUSE A2AEP1_MOUSE --------------CQLAIIPLGTGNDLARVLGWGAVWSKGTSP--LDI-----LSRVEQ Q6DIC8_MOUSE Q6DIC8_MOUSE --------------CQLAIIPLGTGNDLARVLGWGAVWSKGTSP--LDI-----LSRVEQ Q4SB53_TETNG Q4SB53_TETNG LPPDGELTGSFVSSVSWGSFLWAPATTWPG--SWAGAPPATTTPSCPRS-----WRSWRE Q4SB55_TETNG Q4SB55_TETNG APARRGADRQLCVQCQLGVLPLGTGNDLARVLGWGSACDDDTQL--PQI-----LEKLER Q6A0B7_MOUSE Q6A0B7_MOUSE --------------CQLGVLPLGTGNDLARVLGWGSACDDDTQL--PQI-----LAKLER A6QPL5_BOVIN A6QPL5_BOVIN --------------CQLGVLPLGTGNDLARVLGWGSACDDDTQL--PQI-----LEKLER DGKD_HUMAN DGKD_HUMAN --------------CQLGVLPLGTGNDLARVLGWGSACDDDTQL--PQI-----LEKLER Q53SE4_HUMAN Q53SE4_HUMAN --------------CQLGVLPLGTGNDLARVLGWGSACDDDTQL--PQI-----LEKLER Q4T7K6_TETNG Q4T7K6_TETNG --------------VGEEEEEEEEDED-----------EDEAEA--VCVCVCVWAVPAGR B8JI39_DANRE B8JI39_DANRE --------------CQLGVLPLGTGNDLARVLGWGGLCDDDAQL--LQI-----LEKLER B0R0T0_DANRE B0R0T0_DANRE --------------CQLGVLPLGTGNDLARVLGWGPSCDDDTQL--PQI-----LEKLER B4DYW1_HUMAN B4DYW1_HUMAN --------------CQLGVLPLGTGNDLARVLGWGGSYDDDTQL--PQI-----LEKLER A8K0I1_HUMAN A8K0I1_HUMAN --------------CQLGVLPLGTGNDLARVLGWGGSYDDDTQL--PQI-----LEKLER B4DZ34_HUMAN B4DZ34_HUMAN --------------CQLGVLPLGTGNDLARVLGWGGSYDDDTQL--PQI-----LEKLER DGKH_HUMAN DGKH_HUMAN --------------CQLGVLPLGTGNDLARVLGWGGSYDDDTQL--PQI-----LEKLER A0JP53_MOUSE A0JP53_MOUSE --------------CQLGVLPLGTGNDLARVLGWGGSYDDDTQL--PQI-----LEKLER DGKH_MESAU DGKH_MESAU --------------CQLGVLPLGTGNDLARVLGWGGSYDDDTQL--PQI-----LEKLER MATCH . CONSENSUS ??????????????CQL???PLGTGNDLARVLGWG??????T??????I?????L???E?

DGKK_HUMAN DGKK_HUMAN ASVRILD------------------------RWSVMI---RETPRQTPLLKGQVEMDVPR A2AEP1_MOUSE A2AEP1_MOUSE AHVRILD------------------------RWSVMI---RETPRQAPLLKGQVAMDIPR Q6DIC8_MOUSE Q6DIC8_MOUSE AHVRILD------------------------RWSVMI---RETPRQAPLLKGQVAMDIPR Q4SB53_TETNG Q4SB53_TETNG PAPRCWTGECRGQDGGRGDGRGQGPDDPPVCRWSIMV-YETKFPRQHSVSTVTEDCSEDS Q4SB55_TETNG Q4SB55_TETNG ASTKMLD------------------------RWSIMV-YETKFPRQHSVSTVTEDCSEDS Q6A0B7_MOUSE Q6A0B7_MOUSE ASTKMLD------------------------RWSVMA-YETKLPRQASSSTVTEDFSEDS A6QPL5_BOVIN A6QPL5_BOVIN ASTKMLD------------------------RWSVMA-YETKLPRPVSSSTVTEDLSEGS DGKD_HUMAN DGKD_HUMAN ASTKMLD------------------------RWSVMA-YEAKLPRQASSSTVTEDFSEDS Q53SE4_HUMAN Q53SE4_HUMAN ASTKMLD------------------------RWSVMA-YEAKLPRQASSSTVTEDFSEDS Q4T7K6_TETNG Q4T7K6_TETNG AAAGHRE------------------------RPGPRAGLGGPLRRRRATAADPGEAGEGH B8JI39_DANRE B8JI39_DANRE ATTKMLD------------------------RWSVMT-YEVPTKQTPAIVKDDDPSDSP- B0R0T0_DANRE B0R0T0_DANRE ASTKMLD------------------------RWSIMT-YEIKIPPKHSCPATPEEAEDGQ B4DYW1_HUMAN B4DYW1_HUMAN ASTKMLD------------------------RWSIMT-YELKLPPKASLLPGPPEASEE- A8K0I1_HUMAN A8K0I1_HUMAN ASTKMLD------------------------RWSIMT-YELKLPPKASLLPGPPEASEE- B4DZ34_HUMAN B4DZ34_HUMAN ASTKMLD------------------------RWSIMT-YELKLPPKASLLPGPPEASEE- DGKH_HUMAN DGKH_HUMAN ASTKMLD------------------------RWSIMT-YELKLPPKASLLPGPPEASEE- A0JP53_MOUSE A0JP53_MOUSE ASTKMLD------------------------RWSIMT-YELKLPAKSSLLPEPVAATEE- DGKH_MESAU DGKH_MESAU ASTKMLD------------------------RWSIMT-YELKLPAKASLLPEPPEASGG- MATCH . * . . CONSENSUS A????LD????????????????????????RWS?M???????P????????????????

DGKK_HUMAN DGKK_HUMAN FE----AAAIQHLESAATELNKILKAKYPTEMIIATRFLCSAVEDFVVDIVKAWGQIKQN A2AEP1_MOUSE A2AEP1_MOUSE FE----AAAIKNVESATTELNKILKAKYPTEMVIATRFLCSAVEDFVEDIVKAWHQIKQN Q6DIC8_MOUSE Q6DIC8_MOUSE FE----AAAIKNVESATTELNKILKAKYPTEMVIATRFLCSAVEDFVEDIVKAWHQIKQN Q4SB53_TETNG Q4SB53_TETNG EV----QQILTYEDSVAAHLSKILTSDQHSVVISSAKVLCETVKDFVARVGKAYEKNTES Q4SB55_TETNG Q4SB55_TETNG EV----QQILTYEDSVAAHLSKILTSDQHSVVISSAKVLCETVKDFVARVGKAYEKNTES Q6A0B7_MOUSE Q6A0B7_MOUSE EV----QQILFYEDSVAAHLSKILTSDQHSVVISSAKVLCETVKDFVARVGKAYEKTTES A6QPL5_BOVIN A6QPL5_BOVIN EV----QQILFYEDSVAAHLSKILTSDQHSVVISSAKVLCETVKDFVARVGKAYEKTTES DGKD_HUMAN DGKD_HUMAN EV----QQILFYEDSVAAHLSKILTSDQHSVVISSAKVLCETVKDFVARVGKAYEKTTES Q53SE4_HUMAN Q53SE4_HUMAN EV----QQILFYEDSVAAHLSKILTSDQHSVVISSAKVLCETVKDFVARVGKAYEKTTES Q4T7K6_TETNG Q4T7K6_TETNG HQDAGPVHISQYADSVASHLAKILDSDQHSDVISSAKFLCGTVNEFVAEVGKAYERATEN B8JI39_DANRE B8JI39_DANRE ------LQITQYADSVATHLTKILDSDKHSDVISSAKFLCGTVNDFVAEVGKAYERATEN B0R0T0_DANRE B0R0T0_DANRE ------LQISAYEDSVAAHLTKILNSDQHSVVISSSKVLCETVKEFVSRVGKCYERGSDS B4DYW1_HUMAN B4DYW1_HUMAN ------FYMTIYEDSVATHLTKILNSDEHAVVISSAKTLCETVKDFVAKVEKTYDKTLEN A8K0I1_HUMAN A8K0I1_HUMAN ------FYMTIYEDSVATHLTKILNSDEHAVVISSAKTLCETVKDFVAKVEKTYDKTLEN B4DZ34_HUMAN B4DZ34_HUMAN ------FYMTIYEDSVATHLTKILNSDEHAVVISSAKTLCETVKDFVAKVEKTYDKTLEN DGKH_HUMAN DGKH_HUMAN ------FYMTIYEDSVATHLTKILNSDEHAVVISSAKTLCETVKDFVAKVEKTYDKTLEN A0JP53_MOUSE A0JP53_MOUSE ------FYMTIYEDSVANHLTKIVNSDEHAVVISSAKILCETVKDFVAKVEKAQDRTLEN DGKH_MESAU DGKH_MESAU ------FYMTIYEDSVANHLTKILNSDEHAVVISSAKILCETVKDFVAKVEKAQDKTLEN MATCH :*.: .* **: :. : :: ::: ** :*::** : * : :. CONSENSUS ???????????Y?DSVA?HL?KIL?SD?H??VISS?K?LC?TV?DFV??V?K????????

DGKK_HUMAN DGKK_HUMAN NTAIVSVILK---------------------------SDLMYDRLSVLIDVLAEEAAATS A2AEP1_MOUSE A2AEP1_MOUSE STAVESVILK---------------------------SDLMYDKLSVLIDLLAEDAVAAS Q6DIC8_MOUSE Q6DIC8_MOUSE STAVESVILK---------------------------SDLMYDKLSVLIDLLAEDAVAAS Q4SB53_TETNG Q4SB53_TETNG SEESEAMAKK---------------------------CGVLKEKLDSLLKTLNEESQASS Q4SB55_TETNG Q4SB55_TETNG SEESEAMAKK---------------------------CGVLKEKLDSLLKTLNEESQASS Q6A0B7_MOUSE Q6A0B7_MOUSE SQESEVMAKK---------------------------CSVLKEKLDSLLKTLDDESQASS A6QPL5_BOVIN A6QPL5_BOVIN SEESEVMAKK---------------------------CSVLKEKLDSLLKTLDDESQASS DGKD_HUMAN DGKD_HUMAN SEESEVMAKK---------------------------CSVLKEKLDSLLKTLDDESQASS Q53SE4_HUMAN Q53SE4_HUMAN SEESEVMAKK---------------------------CSVLKEKLDSLLKTLDDESQASS Q4T7K6_TETNG Q4T7K6_TETNG REEADAMARKVTAGARLRKRLCNRCKNQPNLPCVVAQCALLNEKLDSLVKALSEEAEAQP B8JI39_DANRE B8JI39_DANRE KEEADAMAKK---------------------------CAMLNEKLDSLVKALSEDANAQL B0R0T0_DANRE B0R0T0_DANRE SEESDALALK---------------------------CAMLNEKLESLLQTLNLEAQVLS B4DYW1_HUMAN B4DYW1_HUMAN AVVADAVASK---------------------------CSVLNEKLEQLLQALHTDSQAAP A8K0I1_HUMAN A8K0I1_HUMAN AVVADAVASK---------------------------CSVLNEKLEQLLQALHTDSQAAP B4DZ34_HUMAN B4DZ34_HUMAN AVVADAVASK---------------------------CSVLNEKLEQLLQALHTDSQAAP DGKH_HUMAN DGKH_HUMAN AVVADAVASK---------------------------CSVLNEKLEQLLQALHTDSQAAP A0JP53_MOUSE A0JP53_MOUSE TVVAEAVASK---------------------------CSVLNEKLEQLLQALHADSQASR DGKH_MESAU DGKH_MESAU TVVAEAVANK---------------------------CSVLNEKLEQLLQALHADAQASR MATCH : * . :: ::*. *:. * :: . CONSENSUS ???????A?K???????????????????????????C??L?EKL??L???L?????A??

DGKK_HUMAN DGKK_HUMAN AEKSATEYADSSKADRKP--------------------------FIPQIDHIAKCKLELA A2AEP1_MOUSE A2AEP1_MOUSE AERTATAYGSRSQADGKP--------------------------FVPQLDHIARAKLELA Q6DIC8_MOUSE Q6DIC8_MOUSE AERTATAYGSRSQADGKP--------------------------FVPQLDHIARAKLELA Q4SB53_TETNG Q4SB53_TETNG VPHLAPPPTIAEEQEETEGNTPPSPLPHHPPPPPLPHSCSSRSGASPAAAAIFKPREQLM Q4SB55_TETNG Q4SB55_TETNG VPHLAPPPTIAEEQEETEGNTPPSPLPHHAPPPPLPHSCSSRSGASPAAAAIFKPREQLM Q6A0B7_MOUSE Q6A0B7_MOUSE SLSNPPPTIAEEAEDGDG--------SGNIC--SSTGDHLVGS-ACPSRPQIFRPREQLM A6QPL5_BOVIN A6QPL5_BOVIN SLPTPPPTIAEEAEDGDG--------AGGGCGSGSTGAHAVGS-ACPTRPQIFRPREQLM DGKD_HUMAN DGKD_HUMAN SLPNPPPTIAEEAEDGDG--------SGSIC--GSTGDRLVAS-ACPARPQIFRPREQLM Q53SE4_HUMAN Q53SE4_HUMAN SLPNPPPTIAEEAEDGDG--------SGSIC--GSTGDRLVAS-ACPARPQIFRPREQLM Q4T7K6_TETNG Q4T7K6_TETNG VLQVVPAGSLPGQEGGGP--------------------GGGGGGEAGPEAKAYRSKEQLM B8JI39_DANRE B8JI39_DANRE VPAG---SISPDDSDTDQ-------------------------------SRPFRSREQLM B0R0T0_DANRE B0R0T0_DANRE PTALTTPPIVEEEVEEEELEEEDEDLSEESL--TELKE---NETEKGSAHKLFRPREQLV B4DYW1_HUMAN B4DYW1_HUMAN VLPGLSPLIVEEDAVESS--------SEESL--GESKEQLGDDVTKPSSQKAVKPRE-IM A8K0I1_HUMAN A8K0I1_HUMAN VLPGLSPLIVEEDAVESS--------SEESL--GESKEQLGDDVTKPSSQKAVKPRE-IM B4DZ34_HUMAN B4DZ34_HUMAN VLPGLSPLIVEEDAVESS--------SEESL--GESKEQLGDDVTKPSSQKAVKPRE-IM DGKH_HUMAN DGKH_HUMAN VLPGLSPLIVEEDAVESS--------SEESL--GESKEQLGDDVTKPSSQKAVKPRE-IM A0JP53_MOUSE A0JP53_MOUSE VPPGIGPAIPEEDTVESA--------SDESL--GESKDQLVNDIGKPSSQKAVKPRE-IM DGKH_MESAU DGKH_MESAU VPPGVGPAIPEEDAVESS--------SEESL--GESKDQLVNDIAKPSSQKAVKPRE-IM MATCH : : : CONSENSUS ??????????????????????????????????????????????P?????????E???

DGKK_HUMAN DGKK_HUMAN TKAQSLQKSLKLIIFQVEQALDEESRQTISVKNFSSTF-----------FLEDDPEDINQ A2AEP1_MOUSE A2AEP1_MOUSE ERAQKLQQSLKLIIFQVEQVLDEESRQSLSVKNFTSSL-----------FLGDGDDDDSD Q6DIC8_MOUSE Q6DIC8_MOUSE ERAQKLQQSLKLIIFQVEQVLDEESRQSLSVKNFTSSL-----------FLGDGDDDDSD Q4SB53_TETNG Q4SB53_TETNG LRANSLKKAIRQIIEHTEKV---------------------------------------- Q4SB55_TETNG Q4SB55_TETNG LRANSLKKAIRQIIEHTEKV---------------------------------------- Q6A0B7_MOUSE Q6A0B7_MOUSE LRANSLKKAIRQIIEHTEKAVDEQNAQTQEQQGFVLGLSESEKKDLKTDNRVCTSSVHSE A6QPL5_BOVIN A6QPL5_BOVIN LRANSLKKAIRQIIEHTEKAVDEQNAQTQEQEGFILSLSESEKK----DLKSDDRAGHGE DGKD_HUMAN DGKD_HUMAN LRANSLKKAIRQIIEHTEKAVDEQNAQTQEQEGFVLGLSESEEK---MDHRVCPPLSHSE Q53SE4_HUMAN Q53SE4_HUMAN LRANSLKKAIRQIIEHTEKAVDEQNAQTQEQEGFVLGLSESEEK---MDHRVCPPLSHSE Q4T7K6_TETNG Q4T7K6_TETNG LRANSLKKALRQIIEQAEKVVDEQNRHTQVHRMSSSS-----------SIRRENSEELKE B8JI39_DANRE B8JI39_DANRE LRANSLKKALRQIIDQAEKVVDEQNRHTQVQRMSSTS-----------SIKRGSSEDLKE B0R0T0_DANRE B0R0T0_DANRE LRANSLKKALRQIIEQAER----------------------------------------- B4DYW1_HUMAN B4DYW1_HUMAN LRANSLKKAVRQVIEEAGKVMDDPTVHPCEPANQSSDYDSTETDESKEEAKDDGAKESIT A8K0I1_HUMAN A8K0I1_HUMAN LRANSLKKAVRQVIEEAGKVMDDPTVHPCEPANQSSDYDSTETDESKEEAKDDGAKESIT B4DZ34_HUMAN B4DZ34_HUMAN LRANSLKKAVRQVIEEAGKVMDDPTVHPCEPANQSSDYDSTETDESKEEAKDDGAKESIT DGKH_HUMAN DGKH_HUMAN LRANSLKKAVRQVIEEAGKVMDDPTVHPCEPANQSSDYDSTETDESKEEAKDDGAKESIT A0JP53_MOUSE A0JP53_MOUSE LRANSLKKAVRQVIEEAEKVMDEPAVQPSEPVSPSCDYDT-ETD----EAKEDDAKESLS DGKH_MESAU DGKH_MESAU LRANSLKKAVRQVIEEAGKVMDEQTVQPCEPVSPSCDYDSPEAD----DSKDNDTKESPA MATCH :*:.*::::: :* .. : CONSENSUS LRANSLKKA?RQ?I???????D??????????????????????????????????????

DGKK_HUMAN DGKK_HUMAN T-----SPRRRSRRGTLSSISSLK--------------SEDLDNLNLDHLHFTPESIR-- A2AEP1_MOUSE A2AEP1_MOUSE DY--DQSPRHRSRCDILCSIPSLR--------------NEDLDNLDLEHLHIAPETIR-- Q6DIC8_MOUSE Q6DIC8_MOUSE DY--DQSPRHRSRCDILCSIPSLR--------------NEDLDNLDLEHLHIAPETIR-- Q4SB53_TETNG Q4SB53_TETNG -------------GKTPCEKLMGK---------------GSREGTPLLSTKILYPG---- Q4SB55_TETNG Q4SB55_TETNG -------------GKTPCEKLMGK---------------GSREGTPLLSTKILYPG---- Q6A0B7_MOUSE Q6A0B7_MOUSE SCVIAKGRSQRKASRAPCEKLVSKG-LSLGSSASLPPGTGSRDSLPALNTKILYPSVRAG A6QPL5_BOVIN A6QPL5_BOVIN GHSASKGRSLRRVSKSPCEKLISKGSLSPGGSASLPPQSGSRDGLPALNTKILFPNVRAG DGKD_HUMAN DGKD_HUMAN SFGVPKGRSQRKVSKSPCEKLISKGSLSLGSSASLPPQPGSRDGLPALNTKILYPNVRAG Q53SE4_HUMAN Q53SE4_HUMAN SFGVPKGRSQRKVSKSPCEKLISKGSLSLGSSASLPPQPGSRDGLPALNTKILYPNVRAG Q4T7K6_TETNG Q4T7K6_TETNG AEPRECDLGGGAGSLSPASPIVLE-------------KSEGLAAVTFSEESVLC------ B8JI39_DANRE B8JI39_DANRE AETRQNTLSPTATTPILLEK------------------SESFGTVLFSEESVQC------ B0R0T0_DANRE B0R0T0_DANRE ------------------------------------------------------------ B4DYW1_HUMAN B4DYW1_HUMAN VKTAPRSPDARASYGHSQTDSVPG-----------PAVAASKENLPVLNTRIICPGLRAG A8K0I1_HUMAN A8K0I1_HUMAN VKTAPRSPDARASYGHSQTDSVPG-----------PAVAASKENLPVLNTRIICPGLRAG B4DZ34_HUMAN B4DZ34_HUMAN VKTAPRSPDARASYGHSQTDSVPG-----------PAVAASKENLPVLNTRIICPGLRAG DGKH_HUMAN DGKH_HUMAN VKTAPRSPDARASYGHSQTDSVPG-----------PAVAASKENLPVLNTRIICPGLRAG A0JP53_MOUSE A0JP53_MOUSE AKTTSQSPDAQASCGHPQTDSVAG-----------PAMATTKENLPVLNTRIICPGLRAG DGKH_MESAU DGKH_MESAU AKSTSQAPEAQAIRGHFQTDSVAG-----------SAMATTKENLPVLNTRIICPGLRAG MATCH CONSENSUS ????????????????????????????????????????????????????????????

DGKK_HUMAN DGKK_HUMAN -------------------------------------FKEKCVMNNYFGIGLDAKISLDF A2AEP1_MOUSE A2AEP1_MOUSE -------------------------------------FKEKCVMNNYFGIGLDAKISLEF Q6DIC8_MOUSE Q6DIC8_MOUSE -------------------------------------FKKKCVMNNYFGIGLDAKISLEF Q4SB53_TETNG Q4SB53_TETNG -----------------------------------DCYTEKCVMNNYFGIGLDAKISLDF Q4SB55_TETNG Q4SB55_TETNG ---------------------------------------QSCA----------------- Q6A0B7_MOUSE Q6A0B7_MOUSE MSGSLPGGSVISRLLI-NADPFNAEP------ENLEYYTEKCVMNNYFGIGLDAKISLDF A6QPL5_BOVIN A6QPL5_BOVIN MSGTLPGGSVISRLLI-NADPFNSEP------ENLEYYTEKCVMNNYFGIGLDAKISLDF DGKD_HUMAN DGKD_HUMAN MSGSLPGGSVISRLLI-NADPFNSEP------ETLEYYTEKCVMNNYFGIGLDAKISLDF Q53SE4_HUMAN Q53SE4_HUMAN MSGSLPGGSVISRLLI-NADPFNSEP------ETLEYYTEKCVMNNYFGIGLDAKISLDF Q4T7K6_TETNG Q4T7K6_TETNG --------------------------------------WEKCVMNNYFGIGLDAKISLEF B8JI39_DANRE B8JI39_DANRE --------------------------------------TEKCVMNNYFGIGLDAKISLEF B0R0T0_DANRE B0R0T0_DANRE ------------------------------------------------------------ B4DYW1_HUMAN B4DYW1_HUMAN LAASIAGSSIINKMLLANIDPFGATPFIDPDLDSVDGYSEKCVMNNYFGIGLDAKISLEF A8K0I1_HUMAN A8K0I1_HUMAN LAASIAGSSIINKMLLANIDPFGATPFIDPDLDSVDGYSEKCVMNNYFGIGLDAKISLEF B4DZ34_HUMAN B4DZ34_HUMAN LAASIAGSSIINKMLLANIDPFGATPFIDPDLDSVDGYSEKCVMNNYFGIGLDAKISLEF DGKH_HUMAN DGKH_HUMAN LAASIAGSSIINKMLLANIDPFGATPFIDPDLDSVDGYSEKCVMNNYFGIGLDAKISLEF A0JP53_MOUSE A0JP53_MOUSE LAASIAGSSIINKMLLANIDPFGATPFIDPDLDSLDGYSEKCVMNNYFGIGLDAKISLEF DGKH_MESAU DGKH_MESAU LAASIAGSSIINKMLLANIDPFGATPFIDPDLDSLDGYSEKCVMNNYFGIGLDAKISLEF MATCH CONSENSUS ???????????????????????????????????????EKCVMNNYFGIGLDAKISL?F

DGKK_HUMAN DGKK_HUMAN NTRRDEHPGQYNSRLKNKMWYGLLGTKELLQRSYRKLEERVHLECDG--------ETISL A2AEP1_MOUSE A2AEP1_MOUSE NSRREEHPEQYNSRLKNKIWYGLLGSKELLQRSYRKLEERIHLECDG--------EAVSL Q6DIC8_MOUSE Q6DIC8_MOUSE NSRREEHPEQYNSRLKNKIWYGLLGSKELLQRSYRKLEERIHLECDG--------EAVSL Q4SB53_TETNG Q4SB53_TETNG NNKRDEHPEKCRSRTKNMMWYGVLGTKELLHRTYKNLEQRVLLEVSGGGSSRDVPACLDV Q4SB55_TETNG Q4SB55_TETNG -----QHP---------------------------------------------------- Q6A0B7_MOUSE Q6A0B7_MOUSE NNKRDEHPEKCRSRTKNMMWYGVLGTKELLHRTYRNLEQKVLLECDG--------RPIPL A6QPL5_BOVIN A6QPL5_BOVIN NNKRDEHPEKCRSRTKNMMWYGVLGTRELLHRTYKNLEQKVLLECDG--------RPIPL DGKD_HUMAN DGKD_HUMAN NNKRDEHPEKCRSRTKNMMWYGVLGTKELLHRTYKNLEQKVLLECDG--------RPIPL Q53SE4_HUMAN Q53SE4_HUMAN NNKRDEHPEKCRSRTKNMMWYGVLGTKELLHRTYKNLEQKVLLECDG--------RPIPL Q4T7K6_TETNG Q4T7K6_TETNG NNKRDEHPRKCSSRTKNMMWYGVLGTKELVQKTYKNLEQRVQLECDG--------VAVPL B8JI39_DANRE B8JI39_DANRE NNKRDENPKKCSSRTKNMMWYGVLGTKELVQKTYKNLEQRVQLECDG--------VSMSL B0R0T0_DANRE B0R0T0_DANRE ------------------------------------------------------------ B4DYW1_HUMAN B4DYW1_HUMAN NNKREEHPEKCRSRTKNLMWYGVLGTRELLQRSYKNLEQRVQLECDG--------QYIPL A8K0I1_HUMAN A8K0I1_HUMAN NNKREEHPEKCRSRTKNLMWYGVLGTRELLQRSYKNLEQRVQLECDG--------QYIPL B4DZ34_HUMAN B4DZ34_HUMAN NNKREEHPEKCRSRTKNLMWYGVLGTRELLQRSYKNLEQRVQLECDG--------QYIPL DGKH_HUMAN DGKH_HUMAN NNKREEHPEKCRSRTKNLMWYGVLGTRELLQRSYKNLEQRVQLECDG--------QYIPL A0JP53_MOUSE A0JP53_MOUSE NNKREEHPEKCRSRTKNLMWYGVLGTRELLQRSYKNLEQRVQLECDG--------QYIPL DGKH_MESAU DGKH_MESAU NNKREEHPEKCRSRTKNLMWYGVLGTRELLQRSYKNLEQRVQLECDG--------QYIPL MATCH CONSENSUS N??R?EHP????SR?KN??WYG?LG??EL????Y??LE????LECDG????????????L

DGKK_HUMAN DGKK_HUMAN PNLQGIV--VLNITSYAGGINFWGSNTATTEYEAPAIDDG-------KLEVVAIFGSVQM A2AEP1_MOUSE A2AEP1_MOUSE PNLQGIV--VLNITSYAGGVNFWGRNRATTEYDVPAINDG-------KLEVVAIFGSVQM Q6DIC8_MOUSE Q6DIC8_MOUSE PNLQGIV--VLNITSYAGGVNFWGRNRATTEYDVPAINDG-------KLEVVAIFGSVQM Q4SB53_TETNG Q4SB53_TETNG PASLDVPAELCSVSSVTGGPSICPACRASLCSTSPATQEEPTSGAGLKKTIPSLLPPLTI Q4SB55_TETNG Q4SB55_TETNG --------------HYAGGTNFWGGTKEDDTFTAPSFDDK-------ILEVVAVFGSMQM Q6A0B7_MOUSE Q6A0B7_MOUSE PSLQGIA--VLNIPSYAGGTNFWGGTKEDDTFAAPSFDDK-------ILEVVAVFGSMQM A6QPL5_BOVIN A6QPL5_BOVIN PSLQGIA--VLNIPSYAGGTNFWGGTKEDDTFTAPSFDDK-------ILEVVAVFGSMQM DGKD_HUMAN DGKD_HUMAN PSLQGIA--VLNIPSYAGGTNFWGGTKEDDTFAAPSFDDK-------ILEVVAVFGSMQM Q53SE4_HUMAN Q53SE4_HUMAN PSLQGIA--VLNIPSYAGGTNFWGGTKEDDTFAAPSFDDK-------ILEVVAVFGSMQM Q4T7K6_TETNG Q4T7K6_TETNG PSLQGLA--VLNIPSYAGGINFWGGTKEDNNFGAPSFDDR-------KLEVVAVFGSMQM B8JI39_DANRE B8JI39_DANRE PSLQGLA--VLNIPSYAGGINFWGGTKEDNNFGAPSFDDK-------KLEVVAVFGSMQM B0R0T0_DANRE B0R0T0_DANRE ------------------------------------------------------------ B4DYW1_HUMAN B4DYW1_HUMAN PSLQGIA--VLNIPSYAGGTNFWGGTKEDDIFAAPSFDDK-------ILEVVAIFDSMQM A8K0I1_HUMAN A8K0I1_HUMAN PSLQGIA--VLNIPSYAGGTNFWGGTKEDDIFAAPSFDDK-------ILEVVAIFDSMQM B4DZ34_HUMAN B4DZ34_HUMAN PSLQGIA--VLNIPSYAGGTNFWGGTKEDDIFAAPSFDDK-------ILEVVAIFDSMQM DGKH_HUMAN DGKH_HUMAN PSLQGIA--VLNIPSYAGGTNFWGGTKEDDIFAAPSFDDK-------ILEVVAIFDSMQM A0JP53_MOUSE A0JP53_MOUSE PSLQGIA--VLNIPSYAGGTNFWGGTKEDDIFAAPSFDDK-------ILEVVAVFDSVQM DGKH_MESAU DGKH_MESAU PSLQGIA--VLNIPSYAGGTNFWGGTKEDDIFAAPSFDDK-------ILEVVAVFDSVQM MATCH CONSENSUS P?LQG????VLNI?SYAGG?NFWG??????????P???D?????????LEVVA?F?S?QM

DGKK_HUMAN DGKK_HUMAN --------------------AMSRIINLHHHR-----------------------IAQCH A2AEP1_MOUSE A2AEP1_MOUSE --------------------AMSRIVNLQQHR-----------------------IAQCH Q6DIC8_MOUSE Q6DIC8_MOUSE --------------------AMSRIVNLQQHR-----------------------IAQCH Q4SB53_TETNG Q4SB53_TETNG RSWRWWPCSAACRWWCLASSTCSTTVSLRCRR-----PPASVRPPVRPPACLTSSVHQCR Q4SB55_TETNG Q4SB55_TETNG --------------------VVSRVINLQHHRIAQVPPPASVRPSARPPACLTSSVHQCR Q6A0B7_MOUSE Q6A0B7_MOUSE --------------------AVSRVIKLQHHR-----------------------IAQCR A6QPL5_BOVIN A6QPL5_BOVIN --------------------AVSRVIKLQHHR-----------------------IAQCR DGKD_HUMAN DGKD_HUMAN --------------------AVSRVIRLQHHR-----------------------IAQCR Q53SE4_HUMAN Q53SE4_HUMAN --------------------AVSRVIRLQHHR-----------------------IAQCR Q4T7K6_TETNG Q4T7K6_TETNG --------------------AVSRVINLQHHR-----------------------IAQCR B8JI39_DANRE B8JI39_DANRE --------------------AMSRVINIQHHR-----------------------IAQCR B0R0T0_DANRE B0R0T0_DANRE ------------------------------------------------------------ B4DYW1_HUMAN B4DYW1_HUMAN --------------------AVSRVIKLQHHR-----------------------IAQCR A8K0I1_HUMAN A8K0I1_HUMAN --------------------AVSRVIKLQHHR-----------------------IAQCR B4DZ34_HUMAN B4DZ34_HUMAN --------------------AVSRVIKLQHHR-----------------------IAQCR DGKH_HUMAN DGKH_HUMAN --------------------AVSRVIKLQHHR-----------------------IAQCR A0JP53_MOUSE A0JP53_MOUSE --------------------AVSRVIKLQHHR-----------------------IAQCR DGKH_MESAU DGKH_MESAU --------------------AVSRVIKLQHHR-----------------------IAQCR MATCH CONSENSUS ????????????????????A?SR???LQ?HR???????????????????????IAQC?

DGKK_HUMAN DGKK_HUMAN EVMITIDGEEGIPVQVDGEAWIQRPGLIKIRYKNAAQMLTRDRDFENSMKMWEYKHTEIQ A2AEP1_MOUSE A2AEP1_MOUSE EVVITIDGEDGVPVQVDGEAWIQKPGLIKIKYKNVAQMLMRDRDFENSMKTWESKHTEIQ Q6DIC8_MOUSE Q6DIC8_MOUSE EVVITIDGEDGVPVQVDGEAWIQKPGLIKIKYKNVAQMLMRDRDFENSMKTWESKHTEIQ Q4SB53_TETNG Q4SB53_TETNG TVKITILGDEGVPVQVDGEAWVQPPGYIKIIHKNRTQTLTRDR----------------- Q4SB55_TETNG Q4SB55_TETNG TVKITILGDEGVPVQVDGEAWVQPPGYIKIIHKNRTQTLTRDR----------------- Q6A0B7_MOUSE Q6A0B7_MOUSE TVKISILGDEGVPVQVDGEAWIQPPGYIRIVHKNRAQTLTRDRAFENTLKSWEDKQKCEL A6QPL5_BOVIN A6QPL5_BOVIN TVKISILGDEGVPVQVDGEAWVQPPGYIRIVHKNRAQTLTRDRAFENTLKSWEDKQKCEL DGKD_HUMAN DGKD_HUMAN TVKISILGDEGVPVQVDGEAWVQPPGYIRIVHKNRAQTLTRDRAFESTLKSWEDKQKCEL Q53SE4_HUMAN Q53SE4_HUMAN TVKISILGDEGVPVQVDGEAWVQPPGYIRIVHKNRAQTLTRDRAFESTLKSWEDKQKCEL Q4T7K6_TETNG Q4T7K6_TETNG QVKITILGEEGVPVQVDGEAWVQPPGIVRIVHKNRAQMLTRDRAFESTLKSWEDKRKGES B8JI39_DANRE B8JI39_DANRE QVKITILGDEGVPVQVDGEAWIQPPGIVQIVHKNRAQMLTRDRAFESTLKSWEDKRKGDS B0R0T0_DANRE B0R0T0_DANRE ------------------------------------------------------------ B4DYW1_HUMAN B4DYW1_HUMAN TVKITIFGDEGVPVQVDGEAWVQPPGIIKIVHKNRAQMLTRDRAFESTLKSWEDKQKCDS A8K0I1_HUMAN A8K0I1_HUMAN TVKITIFGDEGVPVQVDGEAWVQPPGIIKIVHKNRAQMLTRDRAFESTLKSWEDKQKCDS B4DZ34_HUMAN B4DZ34_HUMAN TVKITIFGDEGVPVQVDGEAWVQPPGIIKIVHKNRAQMLTRDRAFESTLKSWEDKQKCDS DGKH_HUMAN DGKH_HUMAN TVKITIFGDEGVPVQVDGEAWVQPPGIIKIVHKNRAQMLTRDRAFESTLKSWEDKQKCDS A0JP53_MOUSE A0JP53_MOUSE TVKITIFGDEGVPVQVDGEAWVQPPGIIKIVHKNRAQMLTRDRAFESTLKSWEDKQKCDS DGKH_MESAU DGKH_MESAU TVKITIFGDEGVPVQVDGEAWVQPPGIIKIVHKNRAQMLTRDRAFESTLKSWEDKQKCDS MATCH CONSENSUS ?V?I?I?G?EGVPVQVDGEAW?Q?PG?I?I??KN?AQ?LTRDR?FE???K?WE?K?????

DGKK_HUMAN DGKK_HUMAN AAPQ-PQLDFQDSQESLSDEEYAQMQHLARLAENLISKLNDLSKIHQHVSV-LMGSVNAS A2AEP1_MOUSE A2AEP1_MOUSE AVQP-PHLDFQESQDSLSDGEYAQMQHLARLAENLISRLTDLSKVHQHVSV-LMDSVNAS Q6DIC8_MOUSE Q6DIC8_MOUSE AVQP-PHLDFQESQDSLSDGEYAQMQHLARLAENLISRLTDLSKVHQHVSV-LMDSVNAS Q4SB53_TETNG Q4SB53_TETNG -------------PEIVSEEEASLISEFGQAAGALIHSIREVAQCHHSLEQELAHAVNAS Q4SB55_TETNG Q4SB55_TETNG -------------PEIVSEEEASLISEFGQAAGALIHSIREVAQCHHSLEQELAHAVNAS Q6A0B7_MOUSE Q6A0B7_MOUSE SRPP----SFSLHPEILSEEEATQMDQFGQAAGGLIHSIREIAQSHRAMEQELAHAVNAS A6QPL5_BOVIN A6QPL5_BOVIN PRAP----SFSLHPEILSEEEATQMDQFGQAAGALIHSIRELAQSHQDVEQELAHAVNAS DGKD_HUMAN DGKD_HUMAN PRPP----SCSLHPEMLSEEEATQMDQFGQAAGVLIHSIREIAQSHRDMEQELAHAVNAS Q53SE4_HUMAN Q53SE4_HUMAN PRPP----SCSLHPEMLSEEEATQMDQFGQAAGVLIHSIREIAQSHRDMEQELAHAVNAS Q4T7K6_TETNG Q4T7K6_TETNG YRASRPRLNSQQSMEYLTEEECAQAQQLGLVADTLINRIREVAKSHKLVEQELAHAVNAT B8JI39_DANRE B8JI39_DANRE -RPSRPRLNSQQSMEYLTEEECAQVQQLGLVADTLISRIREVAKTHKVVEQELAHAVNAS B0R0T0_DANRE B0R0T0_DANRE ------------------------------------------------------------ B4DYW1_HUMAN B4DYW1_HUMAN GKPVLRTHLYIHHAIDLATEEVSQMQLCSQAAEELITRICDAATIHCLLEQELAHAVNAC A8K0I1_HUMAN A8K0I1_HUMAN GKPVLRTHLYTHHAIDLATEEVSQMQLCSQAAEELITRICDAATIHCLLEQELAHAVNAC B4DZ34_HUMAN B4DZ34_HUMAN GKPVLRTHLYIHHAIDLATEEVSQMQLCSQAAEELITRICDAATIHCLLEQELAHAVNAC DGKH_HUMAN DGKH_HUMAN GKPVLRTHLYIHHAIDLATEEVSQMQLCSQAAEELITRICDAATIHCLLEQELAHAVNAC A0JP53_MOUSE A0JP53_MOUSE GKPVLRTNLYIHPAPDLATEEVSQMRLCSQAAEELITRICDAATIHCLLEQELAHAVNAC DGKH_MESAU DGKH_MESAU GKPVLRTNLYIHPAADLATEEVSQMRLCSQAAEELITRICDAATIHCLLGAGTGSSVNAC MATCH CONSENSUS ????????????????L??EE??Q???????A??LI?????????H??????L???VNA?

DGKK_HUMAN DGKK_HUMAN ANILNDIFYGQDSGNEMGAASCIPIETLSRNDAVDVTFSLKGLYDDTTAFLDEK--LLRS A2AEP1_MOUSE A2AEP1_MOUSE ANILNDVFYSQDSGNEAGAASCIPIETLSRTDAVDVTFSLKGLYDDTKAFLDEN--LLRD Q6DIC8_MOUSE Q6DIC8_MOUSE ANILNDVFYSQDSGNEAGAASCIPIETLSRTDAVDVTFSLKGLYDDTKAFLDEN--LLRD Q4SB53_TETNG Q4SB53_TETNG SKAMDLV-YANSKGS----------GTLGCGLVLQMVVNVKVLLRETELLLAGKMSM--- Q4SB55_TETNG Q4SB55_TETNG SKAMDLV-YANSKGS----------GTLGCGLVLQMVFNVKVLLRETELLLAGKMSM--- Q6A0B7_MOUSE Q6A0B7_MOUSE SKAMERV-YGKPRTA----------EGLNCSFVLEMVNNIRALRSETELLLAGKMALQLD A6QPL5_BOVIN A6QPL5_BOVIN SKSMDRV-YGKPRAT----------EGLSCSLVLEMVNNVRALRSETELLLAGRLALQLD DGKD_HUMAN DGKD_HUMAN SKSMDRV-YGKPRTT----------EGLNCSFVLEMVNNFRALRSETELLLSGKMALQLD Q53SE4_HUMAN Q53SE4_HUMAN SKSMDRV-YGKPRTT----------EGLNCSFVLEMVNNFRALRSETELLLSGKMALQLD Q4T7K6_TETNG Q4T7K6_TETNG ALVLTEAKLSSPEHG--------------------------------------------G B8JI39_DANRE B8JI39_DANRE AAVLSEAFPSKPSSP----------EGLSRSTAVDIVNSSTVLQQETKMLLEGKL-LQLE B0R0T0_DANRE B0R0T0_DANRE ------------------------------------------------------------ B4DYW1_HUMAN B4DYW1_HUMAN SHALNKA---NPRCP----------ESLTRDTATEIAINVKALYNETESLLVGRVPLQLE A8K0I1_HUMAN A8K0I1_HUMAN SHALNKA---NPRCP----------ESLTRDTATEIAINVKALYNETESLLVGRVPLQLE B4DZ34_HUMAN B4DZ34_HUMAN SHALNKA---NPRCP----------ESLTRDTATEIAINVKALYNETESLLVGRVPLQLE DGKH_HUMAN DGKH_HUMAN SHALNKA---NPRCP----------ESLTRDTATEIAINVKALYNETESLLVGRVPLQLE A0JP53_MOUSE A0JP53_MOUSE SHALNKA---NPRFP----------ESLTRDTATEIAINVKALYNETEALLVGRVPLHLE DGKH_MESAU DGKH_MESAU SHALNKA---NPRFP----------ESLTRDTATEIAINVKALYNETESLLVGRVPLQLE MATCH CONSENSUS ???????????????????????????L??????????????L???T???L?????????

DGKK_HUMAN DGKK_HUMAN AEDETALQSALDAMNKEFKKLSEIDWMNPIFVPEEKS----SDTDSRSLR-LKIKFPKLG A2AEP1_MOUSE A2AEP1_MOUSE AEDRAMLQTALDAMNTELRRILAIGWLSQIFFPEEQA----SDTRSLSRR-FRIKFPKLG Q6DIC8_MOUSE Q6DIC8_MOUSE AEDRAMLQTALDAMNTELRRILAIGWLSQIFFPEEQA----SDTRSLSRR-FRIKFPKLG Q4SB53_TETNG Q4SB53_TETNG -----------------------------------------GPLTDFSKR---------- Q4SB55_TETNG Q4SB55_TETNG -----------------------------------------GPLTDFSKR---------- Q6A0B7_MOUSE Q6A0B7_MOUSE PPQKERLGAALIEMDQQLRKLTDTPWLCQPLEPGEEESLQQNVMLDLTKR-SRSGKFRLV A6QPL5_BOVIN A6QPL5_BOVIN PPQKERLTAALAEMDQQLRKLADTPWLCQPMEPGDEE----NVMLDLSKR-SRSGKFRLV DGKD_HUMAN DGKD_HUMAN PPQKEQLGSALAEMDRQLRRLADTPWLCQSAEPGDEE----SVMLDLAKR-SRSGKFRLV Q53SE4_HUMAN Q53SE4_HUMAN PPQKEQLGSALAEMDRQLRRLADTPWLCQSAEPGDEE----SVMLDLAKR-SRSGKFRLV Q4T7K6_TETNG Q4T7K6_TETNG GDRQQQQGAAGRDQDAAGREAAGEPPLAASQEPGARR----GASASLCPAGGVPGGGGAG B8JI39_DANRE B8JI39_DANRE SSQKEELLSTVENLSAELQKLEDIHWICPSMHCSEEE--------SSRVSGKSSMKLKIM B0R0T0_DANRE B0R0T0_DANRE ------------------------------------------------------------ B4DYW1_HUMAN B4DYW1_HUMAN SPHEERVSNALHSVEVELRKLTEIPWLYYILHPNEDE----EPPMDCTKRNNRSTVFRIV A8K0I1_HUMAN A8K0I1_HUMAN SPHEERVSNALHSVEVELQKLTEIPWLYYILHPNEDE----EPPMDCTKRNNRSTVFRIV B4DZ34_HUMAN B4DZ34_HUMAN SPHEERVSNALHSVEVELQKLTEIPWLYYILHPNEDE----EPPMDCTKRNNRSTVFRIV DGKH_HUMAN DGKH_HUMAN SPHEERVSNALHSVEVELQKLTEIPWLYYILHPNEDE----EPPMDCTKRNNRSTVFRIV A0JP53_MOUSE A0JP53_MOUSE SPHEERVSSALHSVEMELQKLTEIPWLYYILRPSEDE----EPPLDCTKRNNKSTVFRIV DGKH_MESAU DGKH_MESAU SPHEERVSSALHSVEVELQKLTEIPWLYYILRPNEDE----EPPMDCTKRNSKSTVFRIV MATCH CONSENSUS ?????????????????????????????????????????????????R??????????

DGKK_HUMAN DGKK_HUMAN KK-KVEEERKPKSGQSVQSFIGNLWHRRHRED---------------------------- A2AEP1_MOUSE A2AEP1_MOUSE KKKQREEGEKPKSSQRFPGFLGKFWRRRNRSN---------------------------- Q6DIC8_MOUSE Q6DIC8_MOUSE KKKQREEGEKPKSSQRFPGFLGKFWRRRNRSN---------------------------- Q4SB53_TETNG Q4SB53_TETNG -------------------SRIHQWGTEEVGAWLDFLCLTEYKDIFTGHDVRGAELLHLE Q4SB55_TETNG Q4SB55_TETNG -------------------SRIHQWGTEEVGAWLDFLCLTEYKDIFTGHDVRGAELLHLE Q6A0B7_MOUSE Q6A0B7_MOUSE TKFKKEKNNKNKEVHSNLGGPVHLWGTEEVAAWLEHLSLCEYKDIFTRHDIRGSELLHLE A6QPL5_BOVIN A6QPL5_BOVIN TKFKKEKNNKNRAARCSLGAPVHLWGTEEVAAWLEHLSLCEYKDIFTRHDIRGSELLHLE DGKD_HUMAN DGKD_HUMAN TKFKKEKNNKNKEAHSSLGAPVHLWGTEEVAAWLEHLSLCEYKDIFTRHDIRGSELLHLE Q53SE4_HUMAN Q53SE4_HUMAN TKFKKEKNNKNKEAHSSLGAPVHLWGTEEVAAWLEHLSLCEYKDIFTRHDIRGSELLHLE Q4T7K6_TETNG Q4T7K6_TETNG TDPEQPERRAAEAGGHPLDLPADA-GPRGGGA---------------------------- B8JI39_DANRE B8JI39_DANRE PKGKKEKERLHKQRSSS--SLSGSWDIKASVC---------------------------- B0R0T0_DANRE B0R0T0_DANRE ------------------------------------------------------------ B4DYW1_HUMAN B4DYW1_HUMAN PKFKKEKVQKQKTSS----QP----GSGDTES---------------------------- A8K0I1_HUMAN A8K0I1_HUMAN PKFKKEKVQKQKTSS----QP----GSGDTES---------------------------- B4DZ34_HUMAN B4DZ34_HUMAN PKFKKEKVQKQKTSS----QPVQKWGTEEVAAWLDLLNLGEYKDIFIRHDIRGAELLHLE DGKH_HUMAN DGKH_HUMAN PKFKKEKVQKQKTSS----QPVQKWGTEEVAAWLDLLNLGEYKDIFIRHDIRGAELLHLE A0JP53_MOUSE A0JP53_MOUSE PKFKKEKAQKQKTSS----QPVQNWGTEEVAAWLDLLNLGEYKEIFIRHDVRGAELLHLE DGKH_MESAU DGKH_MESAU PKFKMEKAQKQKTSS----QP----GPGDTES-------GSY------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

DGKK_HUMAN DGKK_HUMAN --------------------------------------------------------EAEG A2AEP1_MOUSE A2AEP1_MOUSE --------------------------------------------------------RAKA Q6DIC8_MOUSE Q6DIC8_MOUSE --------------------------------------------------------RAKA Q4SB53_TETNG Q4SB53_TETNG RRDLKVPTPRLLPQWNLHFLSLEPGPSRRLGGAGLTVSLLLQDLGVTKVGHMKRILQGIR Q4SB55_TETNG Q4SB55_TETNG RRDLKVPTPRLLPQWNLHFLSLEPGPSRRLGGAGLTVSLLLQDLGVTKVGHMKRILQGIR Q6A0B7_MOUSE Q6A0B7_MOUSE RRDLK-------------------------------------DLGVTKVGHMKRILCGIK A6QPL5_BOVIN A6QPL5_BOVIN RRDLK-------------------------------------DLGVTKVGHMKRILCGIK DGKD_HUMAN DGKD_HUMAN RRDLK-------------------------------------DLGVTKVGHMKRILCGIK Q53SE4_HUMAN Q53SE4_HUMAN RRDLK-------------------------------------DLGVTKVGHMKRILCGIK Q4T7K6_TETNG Q4T7K6_TETNG ------------------------------------------------------------ B8JI39_DANRE B8JI39_DANRE ------------------------------------------------------------ B0R0T0_DANRE B0R0T0_DANRE ------------------------------------------------------------ B4DYW1_HUMAN B4DYW1_HUMAN -------------------------------------------------GSCE------- A8K0I1_HUMAN A8K0I1_HUMAN -------------------------------------------------GSCE------- B4DZ34_HUMAN B4DZ34_HUMAN RRDLK-------------------------------------DLGIPKVGHVKRILQGIK DGKH_HUMAN DGKH_HUMAN RRDLK-------------------------------------DLGIPKVGHVKRILQGIK A0JP53_MOUSE A0JP53_MOUSE RRDLK-------------------------------------DLGIPKVGHMKRILQGIK DGKH_MESAU DGKH_MESAU ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

DGKK_HUMAN DGKK_HUMAN DDPLTPSRSQL A2AEP1_MOUSE A2AEP1_MOUSE DDPPTPSSSQL Q6DIC8_MOUSE Q6DIC8_MOUSE DDPPTPSSSQL Q4SB53_TETNG Q4SB53_TETNG ELNRSSSASEA Q4SB55_TETNG Q4SB55_TETNG ELNRSSSASEA Q6A0B7_MOUSE Q6A0B7_MOUSE ELSRSSPAAEA A6QPL5_BOVIN A6QPL5_BOVIN ELSRGAAAAEA DGKD_HUMAN DGKD_HUMAN ELSRSAPAVEA Q53SE4_HUMAN Q53SE4_HUMAN ELSRSAPAVEA Q4T7K6_TETNG Q4T7K6_TETNG ---PGGRRHGP B8JI39_DANRE B8JI39_DANRE --DVDPAGN-- B0R0T0_DANRE B0R0T0_DANRE ----------- B4DYW1_HUMAN B4DYW1_HUMAN ---ANSPGN-- A8K0I1_HUMAN A8K0I1_HUMAN ---ANSPGN-- B4DZ34_HUMAN B4DZ34_HUMAN ELGRSTPQSEV DGKH_HUMAN DGKH_HUMAN ELGRSTPQSEV A0JP53_MOUSE A0JP53_MOUSE ELERNPPNLV- DGKH_MESAU DGKH_MESAU --EANSPGN-- MATCH CONSENSUS ???????????


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