Alignment of the gene Family HBG051499 of HOVERGEN

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Threshold: 50% 80% 100%
Size: Bigger Smaller Normal
Isoforms are ON
P91579_CIOIN P91579_CIOIN GK-PKVKKGKKRKDPEEDPDFYEDEDDFEDDQ--EVQAKAVPAAAGRNIDSNTNTASSAL Q4SZF5_TETNG Q4SZF5_TETNG ---------MRRKTMKM--------------MLGNESQEAVPAAAGKQVDV-----SIIK ERCC3_DANRE ERCC3_DANRE GRKDKSDR--EKKSKKRY---YEDEEEDEE-VIGGESQEAVPAAAGKQVDE-----SSTK ERCC3_CHICK ERCC3_CHICK GRKER----DKKKSKKRH---YEDEEEEEDDAPGKESQEAVPSAAGKQVED-----SGAK ERCC3_BOVIN ERCC3_BOVIN GKRDRADR-EKKKSKKRH---YEDEEDEEDDAPGNDTQEAVPSAAGKQVDE-----SGTK Q53HW5_HUMAN Q53HW5_HUMAN GKRDRADR-DKKKSRKRH---YEDEEDDEEDAPGNDPQEAVPSAAGKQVDE-----SGTK B3KTH1_HUMAN B3KTH1_HUMAN ------------------------------------------------------------ Q4R9E8_MACFA Q4R9E8_MACFA GKRDRADR-DKKKSRKRH---YEDEEDDEEDAPGNDPQEAVPSAAGKQVDE-----SGTK B3KRG2_HUMAN B3KRG2_HUMAN ------------------------------------------------------------ ERCC3_PONAB ERCC3_PONAB GKRDRADR-DKKKSRKRH---YEDEEDDEEDAPGNDPQEAVPSAAGKQVDE-----SGTK ERCC3_MACFA ERCC3_MACFA GKRDRADR-DKKKSRKRH---YEDEEDDEEDAPGNDPQEAVPSAAGKQVDE-----SGTK A8K359_HUMAN A8K359_HUMAN GKRDRADR-DKKKSRKRH---YEDEEDDEEDAPGNDPQEAVPSAAGKQVDE-----SGTK ERCC3_HUMAN ERCC3_HUMAN GKRDRADR-DKKKSRKRH---YEDEEDDEEDAPGNDPQEAVPSAAGKQVDE-----SGTK Q53QM0_HUMAN Q53QM0_HUMAN GKRDRADR-DKKKSRKRH---YEDEEDDEEDAPGNDPQEAVPSAAGKQVDE-----SGTK A0MQ57_CRIGR A0MQ57_CRIGR GKRDRVDR-DKKKSKKRQ---YEEEEEDEDDTPGNDSQEAVPSAAGKQVDE-----SGTK ERCC3_RAT ERCC3_RAT GKRDRVDR-DKKKSKKRQ---YEEEEEDEDDAPGNESQEAVPSAAGKQVDE-----SSTK Q3U3I5_MOUSE Q3U3I5_MOUSE GKRDRVDR-DKKKSKKRQ---YEEEEEDEDDIPGNESQEAVPSAAGKQVDE-----SSTK ERCC3_MOUSE ERCC3_MOUSE GKRDRVDR-DKKKSKKRQ---YEEEEEDEDDIPGNESQEAVPSAAGKQVDE-----SSTK Q3TVD8_MOUSE Q3TVD8_MOUSE ------------------------------------------------------------ B3DLX4_XENTR B3DLX4_XENTR GKRDKADRGDKKKFKRRH---YEEEDEEEEEVPGGEYQEAVPSAAGKQVDE-----AGTK A1L2X9_XENLA A1L2X9_XENLA ------------EVQRRH---YEEEDEEEDELPGGEYQEAVPSAAGKQVDE-----AGTK MATCH CONSENSUS ????????????K????????YE?E???E????G???QEAVP?AAGKQVD?????????K

P91579_CIOIN P91579_CIOIN LDKFGAKDYRSNMEMKKDHASRPLYLAPDGHIFLESFSPVYKHARDFLIAISEPICRPKF Q4SZF5_TETNG Q4SZF5_TETNG QDEYGAKDYRSQMQMKDDHASRPLWVAPDGHIFLEAFSPVYKYAQDFLIAIAEPVCRPTH ERCC3_DANRE ERCC3_DANRE LDEYGAKDYRLQMLLKNDHSSRPLWVAPDGHIFLEAFSPVYKYAQDFLVAISEPVCRPTH ERCC3_CHICK ERCC3_CHICK LDEYGAKDYRLQMPLKADNASRPLWVAPDGHIFLEAFSPVYKYAQDFLVAIAEPVCRPTH ERCC3_BOVIN ERCC3_BOVIN VDEYGAKDYRLQMPLKDDHTSRPLWVAPDGHIFLEAFSPVYKYAQDFLVAIAEPVCRPTH Q53HW5_HUMAN Q53HW5_HUMAN VDEYGAKDYRLQMPLKDDHTSRPLWVAPDGHIFLEAFSPVYKYAQDFLVAIAEPVCRPTH B3KTH1_HUMAN B3KTH1_HUMAN ------------MPLKDDHTSRPLWVAPDGHIFLEAFSPVYKYAQDFLVAIAEPVCRPTH Q4R9E8_MACFA Q4R9E8_MACFA VDEYGAKDYRLQMPLKDDHTSRPLWVAPDGHIFLEAFSPVYKYAQDFLVAIAEPVCRPTH B3KRG2_HUMAN B3KRG2_HUMAN ------------MPLKDDHTSRPLWVAPDGHIFLEAFSPVYKYAQDFLVAIAEPVCRPTH ERCC3_PONAB ERCC3_PONAB VDEYGAKDYRLQMPLKDDHTSRPLWVAPDGHIFLEAFSPVYKYAQDFLVAIAESVCRPTH ERCC3_MACFA ERCC3_MACFA VDEYGAKDYRLQMPLKDDHTSRPLWVAPDGHIFLEAFSPVYKYAQDFLVAIAEPVCRPTH A8K359_HUMAN A8K359_HUMAN VDEYGAKDYRLQMPLKDDHTSRPLWVAPDGHIFLEAFSPVYKYAQDFLVAIAEPVCRPTH ERCC3_HUMAN ERCC3_HUMAN VDEYGAKDYRLQMPLKDDHTSRPLWVAPDGHIFLEAFSPVYKYAQDFLVAIAEPVCRPTH Q53QM0_HUMAN Q53QM0_HUMAN VDEYGAKDYRLQMPLKDDHTSRPLWVAPDGHIFLEAFSPVYKYAQDFLVAIAEPVCRPTH A0MQ57_CRIGR A0MQ57_CRIGR VDEYGAKDYRLQMPLKSDHASRPLWVAPDGHIFLEAFSPVYKYAQDFLVAIAEPVCRPTH ERCC3_RAT ERCC3_RAT VDEYGAKDYRQQMPLKGDHTSRPLWVAPDGHIFLEAFSPVYKYAQDFLVAIAEPVCRPTH Q3U3I5_MOUSE Q3U3I5_MOUSE VDEYGAKDYRQQMPLKGDHTSRPLWVAPDGHIFLEAFSPVYKYAQDFLVAIAEPVCRPTH ERCC3_MOUSE ERCC3_MOUSE VDEYGAKDYRQQMPLKGDHTSRPLWVAPDGHIFLEAFSPVYKYAQDFLVAIAEPVCRPTH Q3TVD8_MOUSE Q3TVD8_MOUSE ------------------------------------------------------------ B3DLX4_XENTR B3DLX4_XENTR QDEYGAKDYRLQMPLKMDHSSRPLWVAPDGHIFLEAFSPVYKYAQDFLVAISEPVCRPSH A1L2X9_XENLA A1L2X9_XENLA QDEYGAKDYRLQMPLKGDHSSRPLWVAPDGHIFLEAFSPVYKYAQDFLVAISEPVCRPSH MATCH CONSENSUS ?DEYGAKDYR?QMPLK?DH?SRPLWVAPDGHIFLEAFSPVYKYAQDFLVAI?EPVCRPTH

P91579_CIOIN P91579_CIOIN IHEFRLTPYSLYAAVSVGLDTEDIIEYLGRLSKTSIPPGIVEFIRLCTQSYGKVKLVLKH Q4SZF5_TETNG Q4SZF5_TETNG IHEYKLTAYSLYAAVSVGLQTSDIVEYLQKLSKTSVPDGIVQFIKLCTVSYGKVKLVLKH ERCC3_DANRE ERCC3_DANRE AHEYKLTAYSLYAAVSVGLQTSDIIEYLQKLSKTSVPDGIVQFIKLCTVSYGKVKLVLKH ERCC3_CHICK ERCC3_CHICK IHEYKLTAYSLYAAVSVGLQTSDITEYLQKLSKTGVPEGIIQFIKLCTVSYGKVKLVLKR ERCC3_BOVIN ERCC3_BOVIN VHEYKLTAYSLYAAVSVGLQTSDITDYLRKLSKTGVPEGIIQFIKLCTVSYGKVKLVLKH Q53HW5_HUMAN Q53HW5_HUMAN VHEYKLTAYSLYAAVSVGLQTSDITEYLRKLSKTGVPDGIMQFIKLCTVSYGKVKLVLKH B3KTH1_HUMAN B3KTH1_HUMAN VHEYKLTAHSLYAAVSVGLQTSDITEYLRKLSKTGVPDGIMQFIKLCTVSYGKVKLVLKH Q4R9E8_MACFA Q4R9E8_MACFA VHEYELTAYSLYAVVSVGLQTSDITEYLRKLSKTGVSDGIMQFIKLCTVSYGKVKLVLKH B3KRG2_HUMAN B3KRG2_HUMAN VHEYKLTAYSLYAAVSVGLQTSDITEYLRKLSKTGVPDGIMQFIKLCTVSYGKVKLVLKH ERCC3_PONAB ERCC3_PONAB VHEYKLTAYSLYAAVSVGLQTSDITEYLRKLSKTGVPDGIMQFIKLCTVSYGKVKLVLKH ERCC3_MACFA ERCC3_MACFA VHEYKLTAYSLYAAVSVGLQTSDITEYLRKLSKTGVPDGIMQFIKLCTVSYGKVKLVLKH A8K359_HUMAN A8K359_HUMAN VHEYKLTAYSLYAAVSVGLQTSDITEYLRKLSKTGVPDGIMQFIKLCTVSYGKVKLVLKH ERCC3_HUMAN ERCC3_HUMAN VHEYKLTAYSLYAAVSVGLQTSDITEYLRKLSKTGVPDGIMQFIKLCTVSYGKVKLVLKH Q53QM0_HUMAN Q53QM0_HUMAN VHEYKLTAYSLYAAVSVGLQTSDITEYLRKLSKTGVPDGIMQFIKLCTVSYGKVKLVLKH A0MQ57_CRIGR A0MQ57_CRIGR VHEYKLTAYSLYAAVSVGLQTSDITEYLKKLSKTGVPDGIMQFIKLCTVSYGKVKLVLKH ERCC3_RAT ERCC3_RAT VHEYKLTAYSLYAAVSVGLQTSDITEYLRKLSKTGVPDGIIQFIKLCTVSYGKVKLVLKH Q3U3I5_MOUSE Q3U3I5_MOUSE VHEYKLTAYSLYAAVSVGLQTSDITEYLRKLSKTGVPDGIIQFIKLCTVSYGKVKLVLKH ERCC3_MOUSE ERCC3_MOUSE VHEYKLTAYSLYAAVSVGLQTSDITEYLRKLSKTGVPDGIIQFIKLCTVSYGKVKLVLKH Q3TVD8_MOUSE Q3TVD8_MOUSE ------------------------------------------------------------ B3DLX4_XENTR B3DLX4_XENTR THEYKLTAYSLYAAVSVGLQTSDIVEYLQKLSKTGVPEGIVQFIKLCTVSYGKVKLVLKH A1L2X9_XENLA A1L2X9_XENLA IHEYKLTAYSLYAAVSVGLQTSDIVEYLQKLSKTGVPEGIVQFIKLCTVSYGKVKLVLKH MATCH CONSENSUS ?HEYKLTAYSLYAAVSVGLQTSDI?EYL?KLSKTGVP?GI?QFIKLCTVSYGKVKLVLKH

P91579_CIOIN P91579_CIOIN NKYYVESSHVDVIQTLLRDYVIASCRKAVTEEENGEATTSGGLQVSTLVSKQGLQVN--K Q4SZF5_TETNG Q4SZF5_TETNG NRYFVESAFPDVIQQLLQDTVIRECRLRTADGADTE------LITEVIHSKSAVYAS--- ERCC3_DANRE ERCC3_DANRE NRYFVESAFPDVIQRLLQDTVIRDCRLRSAEGEETE------LITETISSKSAISKS-QQ ERCC3_CHICK ERCC3_CHICK NRYFVESTHPDVIQQLLQDHVIKDCRLRNAEGEETE------LITETFTSKSAISKS-SE ERCC3_BOVIN ERCC3_BOVIN NRYFVESSHPDVIQHLLQDPVIRECRLRNSEGEATE------LITETFTSKSAIAKS-VE Q53HW5_HUMAN Q53HW5_HUMAN NRYFVESCHPDVIQHLLQDPVIRECRLRNSEGEATE------LITETFTSKSAIPKT-AE B3KTH1_HUMAN B3KTH1_HUMAN NRYFVESCHPDVIQHLLQDPVIRECRLRNSEGEATE------LITETFTSKSAISKT-AE Q4R9E8_MACFA Q4R9E8_MACFA NRYFVESSHPDVIQHLLQDPVIRECRLRNSEGEATE------LITETFTSKSAISKT-AE B3KRG2_HUMAN B3KRG2_HUMAN NRYFVESCHPDVIQHLLQDPVIRECRLRNSEGEATE------LITETFTSKSAISKT-AE ERCC3_PONAB ERCC3_PONAB NRYFVESSHPDVIQHLLQDPVIRECRLRNSEGEATE------LITETFTSKSAISKT-AE ERCC3_MACFA ERCC3_MACFA NRYFVESSHPDVIQHLLQDPVIRECRLRNSEGEATE------LITETFTSKSAISKT-AE A8K359_HUMAN A8K359_HUMAN NRYFVESCHPDVIQHLLQDPVIRECRLRNSEGEATE------LITETFTSKSAISKT-AE ERCC3_HUMAN ERCC3_HUMAN NRYFVESCHPDVIQHLLQDPVIRECRLRNSEGEATE------LITETFTSKSAISKT-AE Q53QM0_HUMAN Q53QM0_HUMAN NRYFVESCHPDVIQHLLQDPVIRECRLRNSEGEATE------LITETFTSKSAISKT-AE A0MQ57_CRIGR A0MQ57_CRIGR NRYFVESSHPDVIQHLLQDPVIRECRLRNAEGEATE------LITETFTSKSAISKT-AE ERCC3_RAT ERCC3_RAT NRYFVESSHPDVIQHLLQDPVIRECRLRNAEGEATE------LITETFTSKSAISKT-VE Q3U3I5_MOUSE Q3U3I5_MOUSE NRYFVESSHPDVIQHLLQDPVIRECRLRNAEGEATE------LITETFTSKSAISKTAAE ERCC3_MOUSE ERCC3_MOUSE NRYFVESSHPDVIQHLLQDPVIRECRLRNAEGEATE------LITETFTSKSAISKTAAE Q3TVD8_MOUSE Q3TVD8_MOUSE ------------------------------------------------------------ B3DLX4_XENTR B3DLX4_XENTR NRYFVESTHPEVIQELLQDSVIRGCRLRDAEGNETD------LITETFLSKSAISKASET A1L2X9_XENLA A1L2X9_XENLA NRYFVESTHPEVIQELLQHTVIRSCRLRDAEGNETE------LITETFTSKSAISKT-SE MATCH CONSENSUS NRYFVES?HPDVIQ?LLQD?VIR?CRLR??EGE?TE??????LITETF?SKSAI?K????

P91579_CIOIN P91579_CIOIN PSNNAGEGQTAEDQ-NESAVPKDIYDFYEQIDKD-------------------------- Q4SZF5_TETNG Q4SZF5_TETNG -----TSQQSSDSQMSSQQVPEDIFSYYEQMDKDXXXXXXXXXXXXXXXXXXXXXXXXXX ERCC3_DANRE ERCC3_DANRE DNGGPSSSQPADGQRSGTQVPEDIFSYYEQMDKE-------------------------- ERCC3_CHICK ERCC3_CHICK SGFGPSTSQEADVQ-NKPDVPADLYEFYEQMDKD-------------------------- ERCC3_BOVIN ERCC3_BOVIN GSGGPSTSRVTDPQ-GKSDIPTDLFDFYEQMDKD-------------------------- Q53HW5_HUMAN Q53HW5_HUMAN SSGGPSTSRVTDPQ-GKSDIPMDLFDFYEQMDKD-------------------------- B3KTH1_HUMAN B3KTH1_HUMAN SSGGPSTSRVTDPQ-GKSDIPMDLFDFYEQMDKD-------------------------- Q4R9E8_MACFA Q4R9E8_MACFA GSGGPSTSRVTDPQ-GKSDIPMDLFDFYEQMDKD-------------------------- B3KRG2_HUMAN B3KRG2_HUMAN SSGGPSTSRVTDPQ-GKSDIPMDLFDFYEQMDKD-------------------------- ERCC3_PONAB ERCC3_PONAB SSGGPSTSRVTDPQ-GKSDIPMDLFDFYEQMDKD-------------------------- ERCC3_MACFA ERCC3_MACFA GSGGPSTSRVTDPQ-GKSDIPMDLFDFYEQMDKD-------------------------- A8K359_HUMAN A8K359_HUMAN SSGGPSTSRVTDPQ-GKSDIPMDLFDFYEQMDKD-------------------------- ERCC3_HUMAN ERCC3_HUMAN SSGGPSTSRVTDPQ-GKSDIPMDLFDFYEQMDKD-------------------------- Q53QM0_HUMAN Q53QM0_HUMAN SSGGPSTSRVTDPQ-GKSDIPMDLFDFYEQMDKD-------------------------- A0MQ57_CRIGR A0MQ57_CRIGR GSGGPSTSQVVDPQ-AKSDIPKDLFEFYEQMDKD-------------------------- ERCC3_RAT ERCC3_RAT GSGGASTSQGVDAQ-AKSDIPKDLFDFYEQMDKD-------------------------- Q3U3I5_MOUSE Q3U3I5_MOUSE GSGGPSTSQGVDAQ-ATSDIPKDLFDFYEQMDKD-------------------------- ERCC3_MOUSE ERCC3_MOUSE GSGGPSTSQGVDAQ-ATSDIPKDLFDFYEQMDKD-------------------------- Q3TVD8_MOUSE Q3TVD8_MOUSE ------------------------------------------------------------ B3DLX4_XENTR B3DLX4_XENTR AASGPSTSQVPEGQ-DKTNVPADLFEFYEQMDKE-------------------------- A1L2X9_XENLA A1L2X9_XENLA TASGPSTSQVPEGQ-DKTNVPADLYEFYEQMDKE-------------------------- MATCH CONSENSUS ???GPSTS???D?Q??????P?DLF?FYEQMDKD??????????????????????????

P91579_CIOIN P91579_CIOIN ---------------------------------------------------------DEN Q4SZF5_TETNG Q4SZF5_TETNG XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX ERCC3_DANRE ERCC3_DANRE ----------------------------------------------------------EE ERCC3_CHICK ERCC3_CHICK ----------------------------------------------------------EE ERCC3_BOVIN ERCC3_BOVIN ----------------------------------------------------------EE Q53HW5_HUMAN Q53HW5_HUMAN ----------------------------------------------------------EE B3KTH1_HUMAN B3KTH1_HUMAN ----------------------------------------------------------EE Q4R9E8_MACFA Q4R9E8_MACFA ----------------------------------------------------------EE B3KRG2_HUMAN B3KRG2_HUMAN ----------------------------------------------------------EE ERCC3_PONAB ERCC3_PONAB ----------------------------------------------------------EE ERCC3_MACFA ERCC3_MACFA ----------------------------------------------------------EE A8K359_HUMAN A8K359_HUMAN ----------------------------------------------------------EE ERCC3_HUMAN ERCC3_HUMAN ----------------------------------------------------------EE Q53QM0_HUMAN Q53QM0_HUMAN ----------------------------------------------------------EE A0MQ57_CRIGR A0MQ57_CRIGR ----------------------------------------------------------EE ERCC3_RAT ERCC3_RAT ----------------------------------------------------------EE Q3U3I5_MOUSE Q3U3I5_MOUSE ----------------------------------------------------------EE ERCC3_MOUSE ERCC3_MOUSE ----------------------------------------------------------EE Q3TVD8_MOUSE Q3TVD8_MOUSE ------------------------------------------------------------ B3DLX4_XENTR B3DLX4_XENTR ----------------------------------------------------------EE A1L2X9_XENLA A1L2X9_XENLA ----------------------------------------------------------EE MATCH CONSENSUS ??????????????????????????????????????????????????????????EE

P91579_CIOIN P91579_CIOIN ATEETQVVSFEVNQEMVETLQKRCIELEYPLLAEYDFRNDTINKDLKIDLKPTTVLRPYQ Q4SZF5_TETNG Q4SZF5_TETNG XXXXXXXXXXXXXXXXXEELQKRCIHLEYPLLAEYDFRNDSVNPDINIDLKPTAVLRPYQ ERCC3_DANRE ERCC3_DANRE EEEETQTVSFEIRQEMIEELQKRCIQLEYPLLAEYDFRNDTVNPDINMDLKPTAVLRPYQ ERCC3_CHICK ERCC3_CHICK EEEETQTVSFEVKQEMIEELQKRCIHLDYPLLAEYDFRNDSVNPDINIDLKPTAVLRPYQ ERCC3_BOVIN ERCC3_BOVIN EEEETQTVSFEVKQEMIEELQKRCIHLEYPLLAEYDFRNDSVNPDINIDLKPTAVLRPYQ Q53HW5_HUMAN Q53HW5_HUMAN EEEETQTVSFEVKQEMIEELQKRCIHLEYPLLAEYDFRNDSVNPDINIDLKPTAVLRPYQ B3KTH1_HUMAN B3KTH1_HUMAN EEEETQTVSFEVKQEMIGELQKRCIHLEYPLLAEYDFRNDSVNPDINIDLKPTAVLRPYQ Q4R9E8_MACFA Q4R9E8_MACFA EEEETQTVSFEVKQEMIEELQKRCIHLEYPLLAEYDFRNDSVNPDINIDLKPTAVLRPYQ B3KRG2_HUMAN B3KRG2_HUMAN EEEETQTVSFEVKQEMIEELQKRCIHLEYPLLAEYDFRNDSVNPDINIDLKPTAVLRPYQ ERCC3_PONAB ERCC3_PONAB EEEETQTVSFEVKQEMIEELQKRCIHLEYPLLAEYDFRNDSVNPDINIDLKPTAVLRPYQ ERCC3_MACFA ERCC3_MACFA EEEETQTVSFEVKQEMIEELQKRCIHLEYPLLAEYDFRNDSVNPDINIDLKPTAVLRPYQ A8K359_HUMAN A8K359_HUMAN EEEETQTVSFEVKQEMIEELQKRCIHLEYPLLAEYDFRNDSVNPDINIDLKPTAVLRPYQ ERCC3_HUMAN ERCC3_HUMAN EEEETQTVSFEVKQEMIEELQKRCIHLEYPLLAEYDFRNDSVNPDINIDLKPTAVLRPYQ Q53QM0_HUMAN Q53QM0_HUMAN EEEETQTVSFEVKQEMIEELQKRCIHLEYPLLAEYDFRNDSVNPDINIDLKPTAVLRPYQ A0MQ57_CRIGR A0MQ57_CRIGR EEEETQTVSFEVKQEMIEELQKRCIYLEYPLLAEYDFRNDSLNPDINIDLKPTAVLRPYQ ERCC3_RAT ERCC3_RAT EEEETQTVSFEVKQEMIEELQKRCICLEYPLLAEYDFRNDSLNPDINIDLKPTAVLRPYQ Q3U3I5_MOUSE Q3U3I5_MOUSE EEEETQTVSFEVKQEMIEELQKRCICLEYPLLAEYDFRNDTLNPDINIDLKPTAVLRPYQ ERCC3_MOUSE ERCC3_MOUSE EEEETQTVSFEVKQEMIEELQKRCICLEYPLLAEYDFRNDTLNPDINIDLKPTAVLRPYQ Q3TVD8_MOUSE Q3TVD8_MOUSE -----------------EELQKRCICLEYPLLAEYDFRNDTLNPDINIDLKPTAVLRPYQ B3DLX4_XENTR B3DLX4_XENTR EEEETQTVSFEVKQDNIEELQKQCIHLEYPLLAEYDFRNDTMNPDINIDLKPTAVLRPYQ A1L2X9_XENLA A1L2X9_XENLA EEEETQTVSFEVKQEKIEELQKQCIQLEYPLLAEYDFRNDTMNPDINIDLKPTAVLRPYQ MATCH ***:** *:************::* *:::*****:****** CONSENSUS EEEETQTVSFEVKQEMIEELQKRCI?LEYPLLAEYDFRND??NPDINIDLKPTAVLRPYQ

P91579_CIOIN P91579_CIOIN EKSLRKMFGNGRARSGVIVLPCGAGKTLVGVTAACTVRKRCMVLCTSGVAVEQWRSQFKM Q4SZF5_TETNG Q4SZF5_TETNG EKSLRKMFGNGRARSGVIVLPCGAGKSLVGVTAACTVRKRCLVLGNSSVSVEQWKAQFKM ERCC3_DANRE ERCC3_DANRE EKSLRKMFGNGRARSGVIVLPCGAGKSLVGVTAACTVRKRCLVLGNSSVSVEQWKAQFKM ERCC3_CHICK ERCC3_CHICK EKSLRKMFGNGRARSGVIVLPCGAGKSLVGVTAACTVRKRCLVLGNSAVSVEQWKAQFKM ERCC3_BOVIN ERCC3_BOVIN EKSLRKMFGNGRARSGVIVLPCGAGKSLVGVTAACTVRKRCLVLGNSAVSVEQWKAQFKM Q53HW5_HUMAN Q53HW5_HUMAN EKSLRKMFGNGRARSGVIVLPCGAGKSLVGVTAACTVRKRCLVLGNSAVSVEQWKAQFKM B3KTH1_HUMAN B3KTH1_HUMAN EKSLRKMFGNGRARSGVIVLPCGAGKSLVGVTAACTVRKRCLVLGNSAVSVEQWKAQFKM Q4R9E8_MACFA Q4R9E8_MACFA EKSLRKMFGNGRARSGVIVLPCGAGKSLVGVTAACTVRKRCLVLGNSAVSVEQWKAQFKM B3KRG2_HUMAN B3KRG2_HUMAN EKSLRKMFGNGRARSGVIVLPCGAGKSLVGVTAVCTVRKRCLVLGNSAVSVEQWKAQFKM ERCC3_PONAB ERCC3_PONAB EKSLRKMFGNGRARSGVIVLPCGAGKSLVGVTAACTVRKRCLVLGNSAVSVEQWKAQFKM ERCC3_MACFA ERCC3_MACFA EKSLRKMFGNGRARSGVIVLPCGAGKSLVGVTAACTVRKRCLVLGNSAVSVEQWKAQFKM A8K359_HUMAN A8K359_HUMAN EKSLRKMFGNGRARSGVIVLPCGAGKSLVGVTAACTVRKRCLVLGNSAVSVEQWKAQFKM ERCC3_HUMAN ERCC3_HUMAN EKSLRKMFGNGRARSGVIVLPCGAGKSLVGVTAACTVRKRCLVLGNSAVSVEQWKAQFKM Q53QM0_HUMAN Q53QM0_HUMAN EKSLRKMFGNGRARSGVIVLPCGAGKSLVGVTAACTVRKRCLVLGNSAVSVEQWKAQFKM A0MQ57_CRIGR A0MQ57_CRIGR EKSLRKMFGNGRARSGVIVLPCGAGKSLVGVTAACTVRKRCLVLGNSAVSVEQWKAQFKM ERCC3_RAT ERCC3_RAT EKSLRKMFGNGRARSGVIVLPCGAGKSLVGVTAACTVRKRCLVLGNSAVSVEQWKAQFKM Q3U3I5_MOUSE Q3U3I5_MOUSE EKSLRKMFGNGRARSGVIVLPCGAGKSLVGVTAACTVRKRCLVLGNSAVSVEQWKAQFKM ERCC3_MOUSE ERCC3_MOUSE EKSLRKMFGNGRARSGVIVLPCGAGKSLVGVTAACTVRKRCLVLGNSAVSVEQWKAQFKM Q3TVD8_MOUSE Q3TVD8_MOUSE EKSLRKMFGNGRARSGVIVLPCGAGKSLVGVTAACTVRKRCLVLGNSAVSVEQWKAQFKM B3DLX4_XENTR B3DLX4_XENTR EKSLRKMFGNGRARSGVIVLPCGAGKSLVGVTAACTVRKRCLVLGNSAVSVEQWKAQFKM A1L2X9_XENLA A1L2X9_XENLA EKSLRKMFGNGRARSGVIVLPCGAGKSLVGVTAACTVRKRCLVLGNSAVSVEQWKSQFKM MATCH **************************:******.*******:** .*.*:****::**** CONSENSUS EKSLRKMFGNGRARSGVIVLPCGAGKSLVGVTAACTVRKRCLVLGNSAVSVEQWKAQFKM

P91579_CIOIN P91579_CIOIN WSTADDSMICRFTSDAKDRPHGCSIAISTYSMMGHSMKRSYESEKVMEWIRSQEWGLIVL Q4SZF5_TETNG Q4SZF5_TETNG WSTIDDSQICRFTSDAKDKPIGCSVAISTYSMLGHTTKRSWEAERVMEWMRSQEWGLMIL ERCC3_DANRE ERCC3_DANRE WSTIDDSQICRFTSDAKDKPIGCSVAISTYSMLGHTTKRSWEAERVMEWMKSQEWGLIIL ERCC3_CHICK ERCC3_CHICK WSTIDDSQICRFTSDAKDKPIDCSIAISTYSMLGHTTKRSWEAERVMEWLKSREWGLMIL ERCC3_BOVIN ERCC3_BOVIN WSTIDDSQICRFTSDAKDKPIGCSIAISTYSMLGHTTKRSWEAERVMEWLKTQEWGLMIL Q53HW5_HUMAN Q53HW5_HUMAN WSTIDDSQICRFTSDAKDKPIGCSVAISTYSMLGHTTKRSWEAERVMEWLKTQVWGLMIL B3KTH1_HUMAN B3KTH1_HUMAN WSTIDDSQICRFTSDAKDKPIGCSVAISTYSMLGHTTKRSWEAERVMEWLKTQEWGLMIL Q4R9E8_MACFA Q4R9E8_MACFA WSTIDDSQICRFTSDAKDKPIGCSVAISTYSMLGHTTKRSWEAERVMEWLKTQEWGLMIL B3KRG2_HUMAN B3KRG2_HUMAN WSTIDDSQICRFTSDAKDKPIGCSVAISTYSMLGHTTKRSWEAERVMEWLKTQEWGLMIL ERCC3_PONAB ERCC3_PONAB WSTIDDSQICRFTSDAKDKPIGCSVAISTYSMLGHTTKRSWEAERVMEWLKTQEWGLMIL ERCC3_MACFA ERCC3_MACFA WSTIDDSQICRFTSDAKDKPIGCSVAISTYSMLGHTTKRSWEAERVMEWLKTQEWGLMIL A8K359_HUMAN A8K359_HUMAN WSTIDDSQICRFTSDAKDKPIGCSVAISTYPMLGHTTKRSWEAERVMEWLKTQEWGLMIL ERCC3_HUMAN ERCC3_HUMAN WSTIDDSQICRFTSDAKDKPIGCSVAISTYSMLGHTTKRSWEAERVMEWLKTQEWGLMIL Q53QM0_HUMAN Q53QM0_HUMAN WSTIDDSQICRFTSDAKDKPIGCSVAISTYSMLGHTTKRSWEAERVMEWLKTQEWGLMIL A0MQ57_CRIGR A0MQ57_CRIGR WSTIDDSQICRFTSDAKDKPIGCSIAISTYSMLGHTTKRSWEAERVMEWLKTQEWGLMIL ERCC3_RAT ERCC3_RAT WSTIDDSQICRFTSDAKDKPIGCSIAISTYSMLGHTTKRSWEAERVMEWLKTQEWGLMIL Q3U3I5_MOUSE Q3U3I5_MOUSE WSTIDDSQICRFTSDAKDKPIGCSVAISTYSMLGHTTKRSWEAERVMEWLKTQEWGLMIL ERCC3_MOUSE ERCC3_MOUSE WSTIDDSQICRFTSDAKDKPIGCSVAISTYSMLGHTTKRSWEAERVMEWLKTQEWGLMIL Q3TVD8_MOUSE Q3TVD8_MOUSE WSTIDDSQICRFTSDAKDKPIGCSVAISTYSMLGHTTKRSWEAERVMEWLKTQEWGLMIL B3DLX4_XENTR B3DLX4_XENTR WSTIDDSQICRFTSDAKDKPIGCSIAISTYSMLGHTTKRSWEAERVMEWLKSQEWGLMIL A1L2X9_XENLA A1L2X9_XENLA WSTIDDSQICRFTSDAKDKPIGCSIAISTYSMLGHTTKRSWEAERVMEWLKSQEWGLMIL MATCH *** *** **********:* .**:*****.*:**: ***:*:*:****:::: ***::* CONSENSUS WSTIDDSQICRFTSDAKDKPIGCS?AISTYSMLGHTTKRSWEAERVMEWLK?QEWGLMIL

P91579_CIOIN P91579_CIOIN DEVHTIPAKQFRRVLTVVQSHCKLGLTATLVREDDKISDLNFLIGPKLYEANWMELQNGG Q4SZF5_TETNG Q4SZF5_TETNG DEVHTIPAKMFRRVLTIVQAHCKLGLTATLVREDDKIVDLNFLIGPKLFEANWMELQNNG ERCC3_DANRE ERCC3_DANRE DEVHTIPAKMFRRVLTIVQAHCKLGLTATLVREDDKIVDLNFLIGPKLYEANWMELQNNG ERCC3_CHICK ERCC3_CHICK DEVHTIPAKMFRRVLTIVQAHCKLELTATLVREDDKIVDLNFLIGPKLYEANWMELQNSG ERCC3_BOVIN ERCC3_BOVIN DEVHTIPAKMFRRVLTIVQAHCKLGLTATLVREDDKIVDLNFLIGPKLYEANWMELQNSG Q53HW5_HUMAN Q53HW5_HUMAN DEVHTIPAKMFRRVLTIVQAHCKLGLTATLVREDDKIVDLNFLIGPKLYEANWMELQNNG B3KTH1_HUMAN B3KTH1_HUMAN DEVHTIPAKMFRRVLTIVQAHCKLGLTATLVREDDKIVDLNFLIGPKLYEANWMELQNNG Q4R9E8_MACFA Q4R9E8_MACFA DEVHTIPAKMFRRVLTIVQAHCKLGLTATLVREDDKIVDLNFLIGPKLYEANWMELQNNG B3KRG2_HUMAN B3KRG2_HUMAN DEVHTIPAKMFRRVLTIVQAHCKLGLTATLVREDDKIVDLNFLIGPKLYEANWMELQNNG ERCC3_PONAB ERCC3_PONAB DEVHTIPAKMFRRVLTIVQAHCKLGLTATLVREDDKIVDLNFLIGPKLYEANWMELQNNG ERCC3_MACFA ERCC3_MACFA DEVHTIPAKMFRRVLTIVQAHCKLGLTATLVREDDKIVDLNFLIGPKLYEANWMELQNNG A8K359_HUMAN A8K359_HUMAN DEVHTIPAKMFRRVLTIVQAHCKLGLTATLVREDDKIVDLNFLIGPKLYEANWMELQNNG ERCC3_HUMAN ERCC3_HUMAN DEVHTIPAKMFRRVLTIVQAHCKLGLTATLVREDDKIVDLNFLIGPKLYEANWMELQNNG Q53QM0_HUMAN Q53QM0_HUMAN DEVHTIPAKMFRRVLTIVQAHCKLGLTATLVREDDKIVDLNFLIGPKLYEANWMELQNNG A0MQ57_CRIGR A0MQ57_CRIGR DEVHTIPAKMFRRVLTIVQAHCKLGLTATLVREDDKIVDLNFLIGPKLYEANWMELQNNG ERCC3_RAT ERCC3_RAT DEVHTIPAKMFRRVLTIVQAHCKLGLTATLVREDDKIVDLNFLIGPKLYEANWMELQNNG Q3U3I5_MOUSE Q3U3I5_MOUSE DEVHTIPARMFRRVLTIVQAHCKLGLTATLVREDDKIVDLNFLIGPKLYEANWMELQNNG ERCC3_MOUSE ERCC3_MOUSE DEVHTIPARMFRRVLTIVQAHCKLGLTATLVREDDKIVDLNFLIGPKLYEANWMELQNNG Q3TVD8_MOUSE Q3TVD8_MOUSE DEVHTIPARMFRRVLTIVQAHCKLGLTATLVREDDKIVDLNFLIGPKLYEANWMELQNNG B3DLX4_XENTR B3DLX4_XENTR DEVHTIPAKMFRRVLTIVQAHCKLGLTATLVREDDKIVDLNFLIGPKLYEANWMELQNNG A1L2X9_XENLA A1L2X9_XENLA DEVHTIPAKMFRRVLTIVQAHCKLGLTATLVREDDKIVDLNFLIGPKLYEANWMELQNNG MATCH ********: ******:**:**** ************ **********:*********.* CONSENSUS DEVHTIPAKMFRRVLTIVQAHCKLGLTATLVREDDKIVDLNFLIGPKLYEANWMELQNNG

P91579_CIOIN P91579_CIOIN FIARVQCAEVWCPMTPEFYREYLSIRSRKRLLLYVMNPNKFRACQFLVRFHERRNDKIVV Q4SZF5_TETNG Q4SZF5_TETNG YIAKVQCAEVWCPMTPEFYREYVAIKTKKRILLYTMNPNKFRACQFLIRFHERRNDKIIV ERCC3_DANRE ERCC3_DANRE YIAKVQCAEVWCPMSPEFYREYVAIKTKKRILLYTMNPNKFRACQFLIRFHERRNDKIIV ERCC3_CHICK ERCC3_CHICK YIAKVQCAEVWCPMSPEFYREYVAIKTKKRILLYTMNPNKFRACQFLIKFHERRNDKIIV ERCC3_BOVIN ERCC3_BOVIN YIAKVQCAEVWCPMSPEFYREYVAIKTKKRILLYTMNPNKFRACQFLIKFHERRNDKIIV Q53HW5_HUMAN Q53HW5_HUMAN YIAKVQCAEVWCPMSPEFYREYVAIKTKKRILLYTMNPNKFRACQFLIKFHERRNDKIIV B3KTH1_HUMAN B3KTH1_HUMAN YIAKVQCAEVWCPMSPEFYREYVAIKTKKRILLYTMNPNKFRACQFLIKFHERRNDKIIV Q4R9E8_MACFA Q4R9E8_MACFA YIAKVQCAEVWCPMSPEFYREYVAIKTKKRILLYTMNPNKFRACQFLIKFHERRNDKIIV B3KRG2_HUMAN B3KRG2_HUMAN YIAKVQCAEVWCPMSPEFYREYVAIKTKKRILLYTMNPNKFRACQFLIKFHERRNDKIIV ERCC3_PONAB ERCC3_PONAB YIAKVQCAEVWCPMSPEFYREYVAIKTKKRILLYTMNPNKFRACQFLIKFHERRNDKIIV ERCC3_MACFA ERCC3_MACFA YIAKVQCAEVWCPMSPEFYREYVAIKTKKRILLYTMNPNKFRACQFLIKFHERRNDKIIV A8K359_HUMAN A8K359_HUMAN YIAKVQCAEVWCPMSPEFYREYVAIKTKKRILLYTMNPNKFRACQFLIKFHERRNDKIIV ERCC3_HUMAN ERCC3_HUMAN YIAKVQCAEVWCPMSPEFYREYVAIKTKKRILLYTMNPNKFRACQFLIKFHERRNDKIIV Q53QM0_HUMAN Q53QM0_HUMAN YIAKVQCAEVWCPMSPEFYREYVAIKTKKRILLYTMNPNKFRACQFLIKFHERRNDKIIV A0MQ57_CRIGR A0MQ57_CRIGR YIAKVQCAEVWCPMSPEFYREYVAIKTKKRILLYTMNPNKFRACQFLIKFHERRNDKIIV ERCC3_RAT ERCC3_RAT YIAKVQCAEVWCPMSPEFYREYVAIKTKKRILLYTMNPNKFRACQFLIKFHERRNDKIIV Q3U3I5_MOUSE Q3U3I5_MOUSE YIAKVQCAEVWCPMSPEFYREYVAIKTKKRILLYTMNPNKFRACQFLIKFHERRNDKIIV ERCC3_MOUSE ERCC3_MOUSE YIAKVQCAEVWCPMSPEFYREYVAIKTKKRILLYTMNPNKFRACQFLIKFHERRNDKIIV Q3TVD8_MOUSE Q3TVD8_MOUSE YIAKVQCAEVWCPMSPEFYREYVAIKTKKRILLYTMNPNKFRACQFLIKFHERRNDKIIV B3DLX4_XENTR B3DLX4_XENTR YIAKVQCAEVWCPMSPEFYREYVAIKTKKRILLYTMNPNKFRACQFLIKFHERRNDKIIV A1L2X9_XENLA A1L2X9_XENLA YIAKVQCAEVWCPMSPEFYREYVAIKTKKRILLYTMNPNKFRACQFLIKFHERRNDKIIV MATCH :**:**********:*******::*:::**:***.************::*********:* CONSENSUS YIAKVQCAEVWCPMSPEFYREYVAIKTKKRILLYTMNPNKFRACQFLIKFHERRNDKIIV

P91579_CIOIN P91579_CIOIN FSDNVFALKEYAVRMGKPYIYGPTTQGERLQILQNFIHNPKVNTIFISKVGDNSIDLPAA Q4SZF5_TETNG Q4SZF5_TETNG FADNVFALKEYAIRLNKPYIYGPTSQGERMQILQNFKHNPKINTIFISKVGDTSFDLPEA ERCC3_DANRE ERCC3_DANRE FADNVFALKEYAIRLNKPYIYGPTSQGERMQILQNFKHNPKINTIFISKVGDTSFDLPEA ERCC3_CHICK ERCC3_CHICK FADNVFALKEYAIRLGKPYIYGPTAQGERMQILQNFKHNPKINTIFISKVGDTSFDLPEA ERCC3_BOVIN ERCC3_BOVIN FADNVFALKEYAIRLNKPYIYGPTSQGERMQILQNFKHNPKINTIFISKVGDTSFDLPEA Q53HW5_HUMAN Q53HW5_HUMAN FADNVFALKEYAIRLNKSYIYGPTSQGERMQILQNFKHNPKINTIFISKVGDTSFDLPEA B3KTH1_HUMAN B3KTH1_HUMAN FADNVFALKEYAIRLNKPYIYGPTSQGERMQILQNFKHNPKINTIFISKVGDTSFDLPEA Q4R9E8_MACFA Q4R9E8_MACFA FADNVFALKEYAIRLNKPYIYGPTSQGERMQILQNFKHNPKINTIFISKVGDTSFDLPEA B3KRG2_HUMAN B3KRG2_HUMAN FADNVFALKEYAIRLNKPYIYGPTSQGERMQILQNFKHNPKINTIFISKVGDTSFDLPEA ERCC3_PONAB ERCC3_PONAB FADNVFALKEYAIRLNKPYIYGPTSQGERMQILQNFKHNPKINTIFISKVGDTSFDLPEA ERCC3_MACFA ERCC3_MACFA FADNVFALKEYAIRLNKPYIYGPTSQGERMQILQNFKHNPKINTIFISKVGDTSFDLPEA A8K359_HUMAN A8K359_HUMAN FADNVFALKEYAIRLNKPYIYGPTSQGERMQILQNFKHNPKINTIFISKVGDTSFDLPEA ERCC3_HUMAN ERCC3_HUMAN FADNVFALKEYAIRLNKPYIYGPTSQGERMQILQNFKHNPKINTIFISKVGDTSFDLPEA Q53QM0_HUMAN Q53QM0_HUMAN FADNVFALKEYAIRLNKPYIYGPTSQGERMQILQNFKHNPKINTIFISKVGDTSFDLPEA A0MQ57_CRIGR A0MQ57_CRIGR FADNVFALKEYAIRLNKPYIYGPTSQGERMQILQNFKHNPKINTIFISKVGDTSFDLPEA ERCC3_RAT ERCC3_RAT FADNVFALKEYAIRLNKPYIYGPTSQGERMQILQNFKHNPKINTIFISKVGDTSFDLPEA Q3U3I5_MOUSE Q3U3I5_MOUSE FADNVFALKEYAIRLNKPYIYGPTSQGERMQILQNFKHNPKINTIFISKVGDTSFDLPEA ERCC3_MOUSE ERCC3_MOUSE FADNVFALKEYAIRLNKPYIYGPTSQGERMQILQNFKHNPKINTIFISKVGDTSFDLPEA Q3TVD8_MOUSE Q3TVD8_MOUSE FADNVFALKEYAIRLNKPYIYGPTSQGERMQILQNFKHNPKINTIFISKVGDTSFDLPEA B3DLX4_XENTR B3DLX4_XENTR FADNVFALKEYAIRLSKPYIYGPTSQGERMHILQNFKHNPKINTIFISKVGDTSFDLPEA A1L2X9_XENLA A1L2X9_XENLA FADNVFALKEYAIRLCKPYIYGPTSQGERMQILQNFKHNPKINTIFISKVGDTSFDLPEA MATCH *:**********:*: *.******:****::***** ****:**********.*:*** * CONSENSUS FADNVFALKEYAIRLNKPYIYGPTSQGERMQILQNFKHNPKINTIFISKVGDTSFDLPEA

P91579_CIOIN P91579_CIOIN NVLIQVSSHGGSRRQEAQRLGRILRAKKGSLAEEYNAFFYSLVSQDTVEVAYSTKRQRFL Q4SZF5_TETNG Q4SZF5_TETNG NVLIQISSHGGSRRQEAQRLGRVLRAKKGMVAEEYNAYFYSLVSQDTQEMAYSTKRQRFL ERCC3_DANRE ERCC3_DANRE NVLIQISSHGGSRRQEAQRLGRVLRAKKGMVAEEYNAYFYSLVSQDTQEMAYSTKRQRFL ERCC3_CHICK ERCC3_CHICK NVLIQISSHGGSRRQEAQRLGRVLRAKKGMVAEEYNAFFYSLVSQDTQEMAYSTKRQRFL ERCC3_BOVIN ERCC3_BOVIN NVLIQISSHGGSRRQEAQRLGRVLRAKKGMVAEEYNAFFYSLVSQDTQEMAYSTKRQRFL Q53HW5_HUMAN Q53HW5_HUMAN NVLIQISSHGGSRRQEAQRLGRVLRAKKGMVAEEYNAFFYSLVSQDTQEMAYSTKRQGFL B3KTH1_HUMAN B3KTH1_HUMAN NVLIQISSHGGSRRQEAQRLGRVLRAKKGMVAEEYNAFFYSLVSQDTQEMAYSTKRQRFL Q4R9E8_MACFA Q4R9E8_MACFA NVLIQISSHGGSRRQEAQRLGRVLRAKKGMVAEEYNAFFYSLVSQDTQEMAYSTKRQRFL B3KRG2_HUMAN B3KRG2_HUMAN NVLIQISSHGGSRRQEAQRLGRVLRAKKGMVAEEYNAFFYSLVSQDTQEMAYSTKRQRFL ERCC3_PONAB ERCC3_PONAB NVLIQISSHGGSRRQEAQRLGRVLRAKKGMVAEEYNAFFYSLVSQDTQEMAYSTKRQRFL ERCC3_MACFA ERCC3_MACFA NVLIQISSHGGSRRQEAQRLGRVLRAKKGMVAEEYNAFFYSLVSQDTQEMAYSTKRQRFL A8K359_HUMAN A8K359_HUMAN NVLIQISSHGGSRRQEAQRLGRVLRAKKGMVAEEYNAFFYSLVSQDTQEMAYSTKRQRFL ERCC3_HUMAN ERCC3_HUMAN NVLIQISSHGGSRRQEAQRLGRVLRAKKGMVAEEYNAFFYSLVSQDTQEMAYSTKRQRFL Q53QM0_HUMAN Q53QM0_HUMAN NVLIQISSHGGSRRQEAQRLGRVLRAKKGMVAEEYNAFFYSLVSQDTQEMAYSTKRQRFL A0MQ57_CRIGR A0MQ57_CRIGR NVLIQISSHGGSRRQEAQRLGRVLRAKKGMVAEEYNAFFYSLVSQDTQEMAYSTKRQRFL ERCC3_RAT ERCC3_RAT NVLIQISSHGGSRRQEAQRLGRVLRAKKGMVAEEYNAFFYSLVSQDTQEMAYSTKRQRFL Q3U3I5_MOUSE Q3U3I5_MOUSE NVLIQISSHGGSRRQEAQRLGRVLRAKKGMVAEEYNAFFYSLVSQDTQEMAYSTKRQRFL ERCC3_MOUSE ERCC3_MOUSE NVLIQISSHGGSRRQEAQRLGRVLRAKKGMVAEEYNAFFYSLVSQDTQEMAYSTKRQRFL Q3TVD8_MOUSE Q3TVD8_MOUSE NVLIQISSHGGSRRQEAQRLGRVLRAKKGMVAEEYNAFFYSLVSQDTQEMAYSTKRQRFL B3DLX4_XENTR B3DLX4_XENTR NVLIQISSHGGSRRQEAQRLGRVLRAKKGMVAEEYNAFFYSLVSQDTQEMAYSTKRQRFL A1L2X9_XENLA A1L2X9_XENLA NVLIQISSHGGSRRQEAQRLGRVLRAKKGMVAEEYNAFFYSLVSQDTQEMAYSTKRQRFL MATCH *****:****************:****** :******:********* *:******* ** CONSENSUS NVLIQISSHGGSRRQEAQRLGRVLRAKKGMVAEEYNAFFYSLVSQDTQEMAYSTKRQRFL

P91579_CIOIN P91579_CIOIN VDQGYSFKAITHLTGIDEEEQLAFTTKDEQHALLQKVLAASDLDAEEEMVPGEFGVGDKG Q4SZF5_TETNG Q4SZF5_TETNG VDQGYSFKVITKLAGMEEED-LMLSSRDEQQQLLQKVLAASDLDAEEEVVAGEVG-ARP- ERCC3_DANRE ERCC3_DANRE VDQGYSFKVITKLAGMEEED-LMFSTRDEQQQLLQKVLAASDLDAEEEVVMGEVG-GKP- ERCC3_CHICK ERCC3_CHICK VDQGYSFKVITKLAGMEEEE-LSFSSKEEQQQLLQKVLQASDLDAEEEVVAGEYG-SKSV ERCC3_BOVIN ERCC3_BOVIN VDQGYSFKVITKLAGMEEED-LAFSTKEEQQQLLQKVLAATDLDAEEEVVAGEFG-SKSS Q53HW5_HUMAN Q53HW5_HUMAN VDQGYSFKVITKLAGMEEED-LAFSTKEEQQQLLQKVLAATDLDAEEEVVAGEFG-SRSS B3KTH1_HUMAN B3KTH1_HUMAN VDQGYSFKVITKLAGMEEED-LAFSTKEEQQQLLQKVLAATDLDAEEEVVAGEFG-SRSS Q4R9E8_MACFA Q4R9E8_MACFA VDQGYSFKVITKLAGMEEED-LAFSTKEEQQQLLQKVLAATDLDAEEEVVAGEFG-SRSS B3KRG2_HUMAN B3KRG2_HUMAN VDQGYSFKVITKLAGMEEED-LAFSTKEEQQQLLQKVLAATDLDAEEEVVAGEFG-SRSS ERCC3_PONAB ERCC3_PONAB VDQGYSFKVITKLAGMEEED-LAFSTKEEQQQLLQKVLAATDLDAEEEVVAGEFG-SRSS ERCC3_MACFA ERCC3_MACFA VDQGYSFKVITKLAGMEEED-LAFSTKEEQQQLLQKVLAATDLDAEEEVVAGEFG-SRSS A8K359_HUMAN A8K359_HUMAN VDQGYSFKVITKLAGMEEED-LAFSTKEEQQQLLQKVLAATDLDAEEEVVAGEFG-SRSS ERCC3_HUMAN ERCC3_HUMAN VDQGYSFKVITKLAGMEEED-LAFSTKEEQQQLLQKVLAATDLDAEEEVVAGEFG-SRSS Q53QM0_HUMAN Q53QM0_HUMAN VDQGYSFKVITKLAGMEEED-LAFSTKEEQQQLLQKVLAATDLDAEEEVVAGEFG-SRSS A0MQ57_CRIGR A0MQ57_CRIGR VDQGYSFKVITKLAGMEEEE-LAFSTKEEQQQLLQKVLAATDLDAEEEVVAGEFG-SRSG ERCC3_RAT ERCC3_RAT VDQGYSFKVITKLAGMEEEE-LAFSTKEEQQQLLQKVLAATDLDAEEEVVAGEFG-SRSG Q3U3I5_MOUSE Q3U3I5_MOUSE VDQGYSFKVITKLAGMEEEE-LSFSTKEEQQQLLQKVLAATDLDAEEEVVAGEFG-SRSG ERCC3_MOUSE ERCC3_MOUSE VDQGYSFKVITKLAGMEEEE-LAFSTKEEQQQLLQKVLAATDLDAEEEVVAGEFG-SRSG Q3TVD8_MOUSE Q3TVD8_MOUSE VDQGYSFKVITKLAGMEEEE-LAFSTKEEQQQLLQKVLAATDLDAEEEVVAGEFG-SRSG B3DLX4_XENTR B3DLX4_XENTR VDQGYSFKVITKLAGMEEEH-LAFSNKEDQQQLLQKVLAASDLDAEEEVVVGEFG-SRST A1L2X9_XENLA A1L2X9_XENLA VDQGYSFKVITKLAGMEEED-LAFSTKEDQHQLLQKVLAASDLDAEEEIVAGEFG-SRSS MATCH ********.**:*:*::**. * ::.:::*: ****** *:*******:* ** * . CONSENSUS VDQGYSFKVITKLAGMEEE??LAFSTKEEQQQLLQKVLAA?DLDAEEEVVAGEFG?SRS?

P91579_CIOIN P91579_CIOIN KGGFRRAGAMSSMSGADDSVYMEYRKTKQR-----KGVHDLFKQFR--------- Q4SZF5_TETNG Q4SZF5_TETNG -QFSRRTGTMSSMSGADDTVYMEYQSRGSKAAAAHKNIHPLFKRFRK-------- ERCC3_DANRE ERCC3_DANRE -QFSRRAGTMSSMSGADDALYMEYQMPRGSKASVGKNIHPLFKRFRK-------- ERCC3_CHICK ERCC3_CHICK -QMSRRTGTMSSMSGADDAVYMEYHSSRSKASSN-KHIHPLLSASGNDVLHVCVL ERCC3_BOVIN ERCC3_BOVIN -QVSRRFGTMSSMSGADDTVYMEYHSSRSK-TST-KHVHPLFKRFRK-------- Q53HW5_HUMAN Q53HW5_HUMAN -QASRRFGTMSSMSGADDTVYMEYHSSRSK-APS-KHVHPLFKRFRK-------- B3KTH1_HUMAN B3KTH1_HUMAN -QASRRFGTMSSMSGADDTVYMEYHSSRSK-APS-KHVHPLFKRFRK-------- Q4R9E8_MACFA Q4R9E8_MACFA -QASRRFGTMSSMSGADDTVYMEYHSSRSK-APS-KHVHPLFKRFRK-------- B3KRG2_HUMAN B3KRG2_HUMAN -QASRRFGTMSSMSGADDTVYMEYHSSRSK-APS-KHVHPLFKRFRK-------- ERCC3_PONAB ERCC3_PONAB -QASRRFGTMSSMSGADDTVYMEYHSSRSK-APS-KHVHPLFKRFRK-------- ERCC3_MACFA ERCC3_MACFA -QASRRFGTMSSMSGADDTVYMEYHSSRSK-APS-KHVHPLFKRFRK-------- A8K359_HUMAN A8K359_HUMAN -QASRRFGTMSSMSGADDTVYMEYHSSRSK-APS-KHVHPLFKRFRK-------- ERCC3_HUMAN ERCC3_HUMAN -QASRRFGTMSSMSGADDTVYMEYHSSRSK-APS-KHVHPLFKRFRK-------- Q53QM0_HUMAN Q53QM0_HUMAN -QASRRFGTMSSMSGADDTVYMEYHSSRSK-APS-KHVHPLFKRFRK-------- A0MQ57_CRIGR A0MQ57_CRIGR -QASRRFGTMSSMSGADDTVYMEYHSSRNK-AST-KHVHPLFKRFRK-------- ERCC3_RAT ERCC3_RAT -QASRRFGTMSSLSGADDTVYMEYHSSRNK-AST-KHVHPLFKRFRK-------- Q3U3I5_MOUSE Q3U3I5_MOUSE -QASRRCGTMSSLSGADDTVYMEYHSSRSK-ASS-KHVHPLFKRFRK-------- ERCC3_MOUSE ERCC3_MOUSE -QASRRCGTMSSLSGADDTVYMEYHSSRSK-ASS-KHVHPLFKRFRK-------- Q3TVD8_MOUSE Q3TVD8_MOUSE -QASRRCGTMSSLSGADDTVYMEYHSSRSK-ASS-KHVHPLFKRFRK-------- B3DLX4_XENTR B3DLX4_XENTR MQVSRRVGTMSSMSGADDAVYMEYHTSRNRGASN-KHVHPLFKRFRK-------- A1L2X9_XENLA A1L2X9_XENLA MQVSRRIGTMSSMSGADDAVYMEYHTPRNKGASN-KHVHPLFKRFRK-------- MATCH ** *:***:*****::****: * :* *:. CONSENSUS ?Q?SRR?GTMSSMSGADD?VYMEYHSSR?K?A???KHVHPLFKRFRK????????


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