Alignment of the gene Family HBG052226 of HOVERGEN
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Threshold:
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80%
100%
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Smaller
Normal
Isoforms are
ON
Q8AWZ9_XENLA
Q8AWZ9_XENLA
PGL
N
T
T
AAS
S
L
L
LTYTNT
H
TPMSMNSTA-
-
-
-
---IKS
F
DEM
E
V
V
Y
I
L
L
L
L
G
F
F
G
F
F
T
F
G
A7LFK5_RABIT
A7LFK5_RABIT
IPP
N
A
T
AVM
P
F
L
TTLGEE
T
AHLQGSSATS
L
A
R
RGPLGD
D
GQM
E
A
L
Y
I
L
M
V
L
G
F
F
G
F
F
T
L
G
KCNE1_RABIT
KCNE1_RABIT
IPP
N
A
T
AVM
P
F
L
TTLGEE
T
AHLQGSSATS
L
A
R
RGPLGD
D
GQM
E
A
L
Y
I
L
M
V
L
G
F
F
G
F
F
T
L
G
Q2KHV0_BOVIN
Q2KHV0_BOVIN
ILS
N
A
T
AVT
P
V
L
TKLWQG
T
VQQGSNMTG-
L
A
R
RFPGHE
D
GKL
A
A
L
Y
I
L
M
V
L
G
F
F
G
F
F
T
L
G
KCNE1_MOUSE
KCNE1_MOUSE
SLP
N
S
T
TVL
P
F
L
ARLWQE
T
AEQGGNVSG-
L
A
R
KSQLRD
D
SKL
E
A
L
Y
I
L
M
V
L
G
F
F
G
F
F
T
L
G
Q545H6_MOUSE
Q545H6_MOUSE
SLP
N
S
T
TVL
P
F
L
ARLWQE
T
AEQGGNVSG-
L
A
R
KSQLRD
D
SKL
E
A
L
Y
I
L
M
V
L
G
F
F
G
F
F
T
L
G
KCNE1_PIG
KCNE1_PIG
ALS
N
S
T
TVL
P
F
L
ASLWQE
T
DEPGGNMSAD
L
A
R
RSQLRD
D
SKL
E
A
L
Y
I
L
M
V
L
G
F
F
G
F
F
T
L
G
KCNE1_RAT
KCNE1_RAT
ALS
N
S
T
TVL
P
F
L
ASLWQE
T
DEPGGNMSAD
L
A
R
RSQLRD
D
SKL
E
A
L
Y
I
L
M
V
L
G
F
F
G
F
F
T
L
G
KCNE1_FELCA
KCNE1_FELCA
ILP
N
T
T
ATT
P
F
L
NALWQG
T
AHQGGNTSG-
L
A
R
RSPGGD
D
SQL
E
A
L
Y
I
L
M
V
L
G
F
F
G
F
F
T
L
G
KCNE1_CAVPO
KCNE1_CAVPO
ILP
N
S
T
AVM
P
F
L
TTVWQG
T
VQPSSNASG-
L
A
R
RSPLRD
D
GKL
E
A
L
Y
I
L
M
V
L
G
F
F
G
F
F
T
L
G
KCNE1_PONAB
KCNE1_PONAB
ILS
N
T
T
AVT
P
F
L
TKLWQE
T
VQQGGNVSG-
L
A
R
RSPRSD
D
GKL
E
A
L
Y
V
L
M
V
L
G
F
F
G
F
F
T
L
G
B4E2L9_HUMAN
B4E2L9_HUMAN
---
-
-
-
---
-
-
-
------
-
------MSG-
L
A
R
RSPRSS
D
GKL
E
A
L
Y
V
L
M
V
L
G
F
F
G
F
F
T
L
G
KCNE1_HUMAN
KCNE1_HUMAN
ILS
N
T
T
AVT
P
F
L
TKLWQE
T
VQQGGNMSG-
L
A
R
RSPRSS
D
GKL
E
A
L
Y
V
L
M
V
L
G
F
F
G
F
F
T
L
G
Q6FHJ6_HUMAN
Q6FHJ6_HUMAN
ILS
N
T
T
AVT
P
F
L
TKLWQE
T
VQQGGNMSG-
L
A
R
RSPRSG
D
GKL
E
A
L
Y
V
L
M
V
L
G
F
F
G
F
F
T
L
G
MATCH
: .:: .:*:*::********:*
CONSENSUS
???N?T???P?L??????T??????????LAR??????D???EALY?LMVLGFFGFFTLG
Q8AWZ9_XENLA
Q8AWZ9_XENLA
I
M
F
S
Y
I
R
S
K
K
R
E
H
S
G
D
P
Y
N
T
Y
I
A
Q
D
C
-
-
E
K
A
K
-
--
K
A
S
V
M
K
R
P
K
PT
C
F
L
V
E
N
KF
A
V
E
Q
P
T
A7LFK5_RABIT
A7LFK5_RABIT
I
M
L
S
Y
I
R
S
Q
K
L
E
H
S
H
D
P
F
N
V
Y
I
E
A
N
D
W
Q
E
K
D
R
A
YF
Q
A
R
V
L
E
S
C
R
-G
C
Y
V
L
E
N
QL
A
V
E
H
P
D
KCNE1_RABIT
KCNE1_RABIT
I
M
L
S
Y
I
R
S
Q
K
L
E
H
S
H
D
P
F
N
V
Y
I
E
A
N
D
W
Q
E
K
D
R
A
YF
Q
A
R
V
L
E
S
C
R
-G
C
Y
V
L
E
N
QL
A
V
E
H
P
D
Q2KHV0_BOVIN
Q2KHV0_BOVIN
I
M
L
S
Y
I
R
S
K
K
L
E
H
S
H
D
P
Y
N
V
Y
I
E
S
D
T
W
Q
E
Q
D
K
A
YF
Q
A
R
I
L
E
S
C
R
-A
C
Y
V
I
E
N
QL
A
V
E
R
P
S
KCNE1_MOUSE
KCNE1_MOUSE
I
M
L
S
Y
I
R
S
K
K
L
E
H
S
H
D
P
F
N
V
Y
I
E
S
D
A
W
Q
E
K
G
K
A
VF
Q
A
R
V
L
E
S
F
R
-A
C
Y
V
I
E
N
QA
A
V
E
Q
P
A
Q545H6_MOUSE
Q545H6_MOUSE
I
M
L
S
Y
I
R
S
K
K
L
E
H
S
H
D
P
F
N
V
Y
I
E
S
D
A
W
Q
E
K
G
K
A
VF
Q
A
R
V
L
E
S
F
R
-A
C
Y
V
I
E
N
QA
A
V
E
Q
P
A
KCNE1_PIG
KCNE1_PIG
I
M
L
S
Y
I
R
S
K
K
L
E
H
S
H
D
P
F
N
V
Y
I
E
S
D
A
W
Q
E
K
G
K
A
LF
Q
A
R
V
L
E
S
F
R
-A
C
Y
A
I
E
N
QA
A
V
E
Q
P
A
KCNE1_RAT
KCNE1_RAT
I
M
L
S
Y
I
R
S
K
K
L
E
H
S
H
D
P
F
N
V
Y
I
E
S
D
A
W
Q
E
K
G
K
A
LF
Q
A
R
V
L
E
S
F
R
-A
C
Y
V
I
E
N
QA
A
V
E
Q
P
A
KCNE1_FELCA
KCNE1_FELCA
I
M
L
S
Y
I
R
S
K
K
L
E
H
S
H
D
P
F
N
V
Y
I
E
S
D
T
W
Q
E
K
D
K
A
YL
Q
A
R
V
L
E
S
Y
K
-A
C
Y
V
I
E
N
QL
A
V
E
R
P
N
KCNE1_CAVPO
KCNE1_CAVPO
I
M
L
S
Y
I
R
S
K
K
L
E
H
S
H
D
P
F
N
V
Y
I
E
S
D
T
W
Q
E
K
D
K
A
FF
Q
A
R
V
L
E
N
C
R
-S
C
C
V
I
E
N
QL
T
V
E
Q
P
N
KCNE1_PONAB
KCNE1_PONAB
I
M
L
S
Y
I
R
S
K
K
L
E
H
S
N
D
P
F
N
V
Y
I
E
S
D
A
W
Q
E
K
D
K
A
YV
Q
A
R
V
L
K
S
Y
R
-A
C
Y
V
V
E
N
HL
A
V
E
Q
P
N
B4E2L9_HUMAN
B4E2L9_HUMAN
I
M
L
S
Y
I
R
S
K
K
L
E
H
S
N
D
P
F
N
V
Y
I
E
S
D
A
W
Q
E
K
D
K
A
YV
Q
A
R
V
L
E
S
Y
R
-S
C
Y
V
V
E
N
HL
A
I
E
Q
P
N
KCNE1_HUMAN
KCNE1_HUMAN
I
M
L
S
Y
I
R
S
K
K
L
E
H
S
N
D
P
F
N
V
Y
I
E
S
D
A
W
Q
E
K
D
K
A
YV
Q
A
R
V
L
E
S
Y
R
-S
C
Y
V
V
E
N
HL
A
I
E
Q
P
N
Q6FHJ6_HUMAN
Q6FHJ6_HUMAN
I
M
L
S
Y
I
R
S
K
K
L
E
H
S
N
D
P
F
N
V
Y
I
E
S
D
A
W
Q
E
K
D
K
A
YV
Q
A
R
V
L
E
S
Y
R
-S
C
Y
V
V
E
N
HL
A
I
E
Q
P
N
MATCH
**:*****:* *** **:*.** : *: : :* ::: : * :**: ::*:*
CONSENSUS
IMLSYIRSKKLEHS?DPFNVYIE?D?WQEK?KA??QARVLES?R??CYV?EN??A?E?P?
Q8AWZ9_XENLA
Q8AWZ9_XENLA
QY
I
P
S
S
-
P
SN
A7LFK5_RABIT
A7LFK5_RABIT
TH
L
P
E
L
K
P
SL
KCNE1_RABIT
KCNE1_RABIT
TH
L
P
E
L
K
P
SL
Q2KHV0_BOVIN
Q2KHV0_BOVIN
AY
L
P
E
M
K
R
SS
KCNE1_MOUSE
KCNE1_MOUSE
TH
L
P
E
L
K
P
LS
Q545H6_MOUSE
Q545H6_MOUSE
TH
L
P
E
L
K
P
LS
KCNE1_PIG
KCNE1_PIG
TH
L
P
E
L
K
P
LS
KCNE1_RAT
KCNE1_RAT
TH
L
P
E
L
K
P
LS
KCNE1_FELCA
KCNE1_FELCA
AH
L
P
E
I
K
P
LS
KCNE1_CAVPO
KCNE1_CAVPO
TY
L
P
E
L
-
-
--
KCNE1_PONAB
KCNE1_PONAB
TH
L
P
G
T
K
P
SP
B4E2L9_HUMAN
B4E2L9_HUMAN
TH
L
P
E
T
K
P
SP
KCNE1_HUMAN
KCNE1_HUMAN
TH
L
P
E
T
K
P
SP
Q6FHJ6_HUMAN
Q6FHJ6_HUMAN
TH
L
P
E
T
K
P
SP
MATCH
::*
CONSENSUS
??LPE?KP??
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.
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.
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