Alignment of the gene Family HBG052488 of HOVERGEN

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Isoforms are ON
PN6BL_HUMAN PN6BL_HUMAN -----------------------MALAMLRDWCRWMGANAERSLLILGIPDDCKEHEFQE PNM6A_HUMAN PNM6A_HUMAN -----------------------MAVTMLQDWCRWMGVNARRGLLILGIPEDCDDAEFQE PNM6B_HUMAN PNM6B_HUMAN -----------------------MAVTMLQDWCRWMGVNARRGLLILGIPEDCDDAEFQE PNMA5_MOUSE PNMA5_MOUSE -----------------------MAVALLDDWCKGMDLDPKKAVLIVGIPVQYTEAAIND B7Z9Y9_HUMAN B7Z9Y9_HUMAN -----------------------MALTLLEDWCKGMDMDPRKALLIVGIPMECSEVEIQD PNMA5_HUMAN PNMA5_HUMAN -----------------------MALTLLEDWCKGMDMDPRKALLIVGIPMECSEVEIQD PNMA3_MOUSE PNMA3_MOUSE -----------------------MPLNLLQDWCRGEHLNTQRSMLILGIPEDCSEDEFEE B2R5S9_HUMAN B2R5S9_HUMAN -----------------------MPLTLLQDWCRGEHLNTRRCMLILGIPEDCGEDEFEE PNMA3_HUMAN PNMA3_HUMAN -----------------------MPLTLLQDWCRGEHLNTRRCMLILGIPEDCGEDEFEE PNMA2_MOUSE PNMA2_MOUSE -----------------------MAVALLEEWCKIMGVDVQKSLLVVDIPVDCGEPEIQT Q5DU13_MOUSE Q5DU13_MOUSE DRAFGPRGFETSWRPSPEAYPGTMAVALLEEWCKIMGVDVQKSLLVVDIPVDCGEPEIQT PNMA2_BOVIN PNMA2_BOVIN -----------------------MALALLEDWCRILSVDDQKSLMVMGIPVDCSEDEIQE PNMA2_MACFA PNMA2_MACFA -----------------------MALALLEDWCRIMSVDEQKSLMVTGIPVDYEEAEIQE PNMA2_PONAB PNMA2_PONAB -----------------------MALALLEDWCRIMSVDEQKSLMVTGIPADYEEAEIQE B3KNY9_HUMAN B3KNY9_HUMAN -----------------------MALALLEDWCRIMSVDEQKSLMVTGIPADFEEAEIQE PNMA2_HUMAN PNMA2_HUMAN -----------------------MALALLEDWCRIMSVDEQKSLMVTGIPADFEEAEIQE Q5U5Z3_HUMAN Q5U5Z3_HUMAN -----------------------MALALLEDWCRIMSVDEQKSLMVTGIPADFEEAEIQE PNMA1_BOVIN PNMA1_BOVIN -----------------------MAMTLLEDWCRGMDVNSQRALLVWGIPVNCDEAEIEE Q6IAP2_HUMAN Q6IAP2_HUMAN -----------------------MAMTLLEDWCRGMDVNSQRALLVWGIPVNCDEAEIEE A8K4L5_HUMAN A8K4L5_HUMAN -----------------------MAMTLLEDWCRGMDVNSQRALLVWGIPVNCDEAEIEE PNMA1_HUMAN PNMA1_HUMAN -----------------------MAMTLLEDWCRGMDVNSQRALLVWGIPVNCDEAEIEE PNMA1_RAT PNMA1_RAT -----------------------MAMTLLEDWCRGMDVNSQRALLVWGIPVNCDETEIEE PNMA1_MOUSE PNMA1_MOUSE -----------------------MAMTLLEDWCRGMDVNSQRALLVWGIPVNCDETEIEE Q3UVU2_MOUSE Q3UVU2_MOUSE -----------------------MAMTLLEDWCRGMDVNSQRALLVWGIPVNCDETEIEE B2RDF6_HUMAN B2RDF6_HUMAN -----------------------MTLRLLEDWCRGMDMNPRKALLIAGISQSCSVAEIEE MOAP1_HUMAN MOAP1_HUMAN -----------------------MTLRLLEDWCRGMDMNPRKALLIAGISQSCSVAEIEE MOAP1_MACFA MOAP1_MACFA -----------------------MTLRLLEDWCRGMDMNPRKALLIAGISQSCSVAEIEE MOAP1_MOUSE MOAP1_MOUSE -----------------------MTLRLLEDWCRGMDMNPRKALLVAGIPPTCGVADIEE Q5BJV6_RAT Q5BJV6_RAT -----------------------MTLRLLEDWCRGMDMNPRKALLVAGIPPTCGVADIEE MATCH *.: :* :**: : .: ::: .*. :: CONSENSUS ???????????????????????M???LL?DWCR?M???????L???GIP??????E??E

PN6BL_HUMAN PN6BL_HUMAN AVRAALSPLGRYRVLTKHFRKELGAKAALVEFAEYLNRSLIPHQIPGNGGPWKVIFLPQV PNM6A_HUMAN PNM6A_HUMAN SLEAALRPMGHFTVLGKAFREEDNATAALVELDREVNYALVPREIPGTGGPWNVVFVPRC PNM6B_HUMAN PNM6B_HUMAN SLEAALRPMGHFTVLGKVFREEDNATAALVELDREVNYALVPREIPGTGGPWNVVFVPRC PNMA5_MOUSE PNMA5_MOUSE ALKEGLPPLCAYKVIGRMFRREDEAKAVLIELPEVVDYTMMPTHIPAEGGAWEVVVKPRS B7Z9Y9_HUMAN B7Z9Y9_HUMAN TVKAGLQPLCAYRVLGRMFRREDNAKAVFIELADTVNYTTLPSHIPGKGGSWEVVVKPRN PNMA5_HUMAN PNMA5_HUMAN TVKAGLQPLCAYRVLGRMFRREDNAKAVFIELADTVNYTTLPSHIPGKGGSWEVVVKPRN PNMA3_MOUSE PNMA3_MOUSE TLHEALKHLGRYRIIGRMFRREENAQAFLVELARDFDYALVPREIEGKGGPWEVVVKPPH B2R5S9_HUMAN B2R5S9_HUMAN TLQEACRHLGRYRVIGRMFRREENAQAILLELAQDIDYALLPREIPGKGGPWEVIVKPRN PNMA3_HUMAN PNMA3_HUMAN TLQEACRHLGRYRVIGRMFRREENAQAILLELAQDIDYALLPREIPGKGGPWEVIVKPRN PNMA2_MOUSE PNMA2_MOUSE VLQEALKCVGSYRLLGKIFQKQDNTSVVLVELMEDTDMSVVPSEVQGKGGVWKVIFKTPN Q5DU13_MOUSE Q5DU13_MOUSE VLQEALKCVGSYRLLGKIFQKQDNTSVVLVELMEDTDMSVVPSEVQGKGGVWKVIFKTPN PNMA2_BOVIN PNMA2_BOVIN VLQEILKPLGRYKLLGKIFRKQENANAVLLELLEDPEVSVIPSKVQGKGGIWKVIFKTPN PNMA2_MACFA PNMA2_MACFA VLQETLKSLGSYRLLGKIFRKQENANAVLLELLEDTDVSAIPSEVQGKGGVWKVVFKTPN PNMA2_PONAB PNMA2_PONAB VLQETLKSLGRYRLLGKIFRKQENANAVLLELLEDTDISAIPSEVQGKGGVWKVIFKTPN B3KNY9_HUMAN B3KNY9_HUMAN VLQETLKSLGRYRLLGKIFRKQENANAVLLELLEDTDVSAIPSEVQGKGGVWKVIFKTPN PNMA2_HUMAN PNMA2_HUMAN VLQETLKSLGRYRLLGKIFRKQENANAVLLELLEDTDVSAIPSEVQGKGGVWKVIFKTPN Q5U5Z3_HUMAN Q5U5Z3_HUMAN VLQETLKSLGRYRLLGKIFRKQENANAVLLELLEDTDVSAIPSEVQGKGGVWKVIFKTPN PNMA1_BOVIN PNMA1_BOVIN TLQAAM-PQVHYRVLGRMFWREENAKAALLELTGTVDYAAIPREMPGKGGVWKVVFKPPT Q6IAP2_HUMAN Q6IAP2_HUMAN TLQAAM-PQVSYRMLGRMFWREENAKAALLELTGAVDYAAIPREMPGKGGVWKVLFKPPT A8K4L5_HUMAN A8K4L5_HUMAN TLQAAM-PQVSYRMLGRMFWREENAKAALLELTGAVDYAAIPREMPGKGGVWKVLFKPPT PNMA1_HUMAN PNMA1_HUMAN TLQAAM-PQVSYRMLGRMFWREENAKAALLELTGAVDYAAIPREMPGKGGVWKVLFKPPT PNMA1_RAT PNMA1_RAT TLQAAM-PQVSYRVLGRMFWREENAKAALLELTGTVDYSLIPREMPGKGGLWKVVFKPPT PNMA1_MOUSE PNMA1_MOUSE TLQAAM-PQVSYRVLGRMFWREENAKAALLELTGAVDYSLIPREMPGKGGLWKVVFKPPT Q3UVU2_MOUSE Q3UVU2_MOUSE TLQAAM-PQVSYRVLGRMFWREENAKAALLELTGAVDYSLIPREMPGKGGLWKVVFKPPT B2RDF6_HUMAN B2RDF6_HUMAN ALQAGLAPLGEYRLLGRMFRRDENRKVALVGLTAETSHALVPKEIPGKGGIWRVIFKPPD MOAP1_HUMAN MOAP1_HUMAN ALQAGLAPLGEYRLLGRMFRRDENRKVALVGLTAETSHALVPKEIPGKGGIWRVIFKPPD MOAP1_MACFA MOAP1_MACFA ALQAGLAPLGEYRLLGRMFRRDENRKVALVGLTAETSHALVPKEIPGKGGIWRVIFKPPD MOAP1_MOUSE MOAP1_MOUSE ALQAGLAPLGEHRLLGRMFRRDENKNVALIGLTVETGSALVPKEIPAKGGVWRVIFKPPD Q5BJV6_RAT Q5BJV6_RAT ALQVGLAPLGEHRLLGRMFRRDENKNVALVGLTVETGSALVPKEIPAKGGVWRVIFKPPD MATCH :. . :: : * .: . :: : : :* .: . ** *.*:. . CONSENSUS ?L?????????YR?LG??F????N????L?EL?????????P?E??GKGG?W?V??K???

PN6BL_HUMAN PN6BL_HUMAN PVIEF--QDMPSFPAQPQGQAVAKAAGAAGEAGAVGEAGGT-NVTKAWVQPWRCTL---- PNM6A_HUMAN PNM6A_HUMAN SGEEFLGLGRVFHFPEQEGQMVESVAGALGVGLR--RV--C------WLRSIGQAV---- PNM6B_HUMAN PNM6B_HUMAN SGEEFLGLGRVFHFPEQEGQMVESVAGALG----VGLRRVC------WLRSIGQAV---- PNMA5_MOUSE PNMA5_MOUSE PDDEF--MNKLIYFLRDEGRRIVDVAKALGFSTVPTGKIEL--------KNLDQDKPKGL B7Z9Y9_HUMAN B7Z9Y9_HUMAN PDDEF--LSRLNYFLKDEGRSMTDVARALG---CCSLPAES-----LDAEVMPQVRSPPL PNMA5_HUMAN PNMA5_HUMAN PDDEF--LSRLNYFLKDEGRSMTDVARALG---CCSLPAES-----LDAEVMPQVRSPPL PNMA3_MOUSE PNMA3_MOUSE SDDEF--LNRLNHFLEEERRTVSDMNRVLGTHSNHSPTKTT-ISADFWV--WAQTLGAVM B2R5S9_HUMAN B2R5S9_HUMAN SDGEF--LNRLNRFLEEERRTVSDMNRVLGSDTNCSAPRVT-ISPEFWT--WAQTLGAAV PNMA3_HUMAN PNMA3_HUMAN SDGEF--LNRLNRFLEEERRTVSDMNRVLGSDTNCSAPRVT-ISPEFWT--WAQTLGAAV PNMA2_MOUSE PNMA2_MOUSE QDTEF--LQRLNLFLEKEGQTVAGMFRALKHEGVSPATPPC-TSPELLAHLTGQAMVHGQ Q5DU13_MOUSE Q5DU13_MOUSE QDTEF--LQRLNLFLEKEGQTVAGMFRALKHEGVSPATPPC-TSPELLAHLTGQAMVHGQ PNMA2_BOVIN PNMA2_BOVIN QDTEF--LERLNLFLEKEGQTVSGMFRALGHQGLSPAAMPC-ISPELLAHVLGQVIAHPP PNMA2_MACFA PNMA2_MACFA QDTEF--LERLNLFLEKEGQTVSGMFRALGHEGMSPATVPC-ISPELLAHLLGQAMAHAP PNMA2_PONAB PNMA2_PONAB QDTEF--LERLNLFLEKEGQTVSGMFRALGHEGVSSATVPC-ISPELLAHLLGQAMAHAP B3KNY9_HUMAN B3KNY9_HUMAN QDTEF--LERLNLFLEKEGQTVSGMFRALGQEGVSPATVPC-ISPELLAHLLGQAMAHAP PNMA2_HUMAN PNMA2_HUMAN QDTEF--LERLNLFLEKEGQTVSGMFRALGQEGVSPATVPC-ISPELLAHLLGQAMAHAP Q5U5Z3_HUMAN Q5U5Z3_HUMAN QDTEF--LERLNLFLEKEGQTVSGMFRALGQEGVSPATVPC-ISPELLAHLLGQAMAHAP PNMA1_BOVIN PNMA1_BOVIN SDAEF--LERLHLFLAREGWTVQDVARVLGFEN--SSPAPG---PDMPAEMLNYILDNVI Q6IAP2_HUMAN Q6IAP2_HUMAN SDAEF--LERLHLFLAREGWTVQDVARVLGFQN--PTPTPG---PEMPAEMLNYILDNVI A8K4L5_HUMAN A8K4L5_HUMAN SDAEF--LERLHLFLAREGWTVQDVARVLGFQN--PTPTPG---PEMPAEMLNYILDNVI PNMA1_HUMAN PNMA1_HUMAN SDAEF--LERLHLFLAREGWTVQDVARVLGFQN--PTPTPG---PEMPAEMLNYILDNVI PNMA1_RAT PNMA1_RAT SDAEF--LERLHLFLAREGWTVQDVARVLGFQN--PAPAPG---PEMPAEMLNYILDNVI PNMA1_MOUSE PNMA1_MOUSE SDAVF--LERLHLFLAREGWTVQDVARVLGFQN--PAPAPG---PETPAEMLNYILDNVI Q3UVU2_MOUSE Q3UVU2_MOUSE SDAVF--LERLHLFLAREGWTVQDVARVLGFQN--PAPAPG---PEMPAEMLNYILDNVI B2RDF6_HUMAN B2RDF6_HUMAN PDNTF--LSRLNEFLAGEGMTVGELSRALGHENGSLDPEQG-MIPEMWAPMLAQAL-EAL MOAP1_HUMAN MOAP1_HUMAN PDNTF--LSRLNEFLAGEGMTVGELSRALGHENGSLDPEQG-MIPEMWAPMLAQAL-EAL MOAP1_MACFA MOAP1_MACFA SDNTF--LSRLNEFLAGEGMTVGELTRALAHENGSLDLEQG-MIPEMWAPMLAQAL-EAL MOAP1_MOUSE MOAP1_MOUSE TDSDF--LCRLNEFLKGEGMTMGELTRVLGNRNDPLGLDPGIMIPEIRAPMLAQALNEAL Q5BJV6_RAT Q5BJV6_RAT ADSDF--LCRLNEFLKGEGMTMGELTRVLGNRNDPLCLDQNVMIPEIRAPMLAQALDEAL MATCH * : : . CONSENSUS ?D??F??L?RL??FL??EG??V????R?LG??????????????????????????????

PN6BL_HUMAN PN6BL_HUMAN QPVLENRA-YRELRPFSRREQPGCEEESFESWVEHAKDMLQLWCHASEREKKRWLLESLG PNM6A_HUMAN PNM6A_HUMAN QPWVEAVR-CQSLGVFSGRDQPAPGEESFEVWLDHTTEMLHVWQGVSERERRRRLLEGLR PNM6B_HUMAN PNM6B_HUMAN QPWVEAVR-YQSLGVFSGRDQPAPGEESFEVWLDHTTEMLHVWQGVSERERRRRLLEGLR PNMA5_MOUSE PNMA5_MOUSE KSLCNNSTCYKKLKVFSGSPFPGPGEESFETWLEEVTELMQLWQ-VSEREKKQCLLESLR B7Z9Y9_HUMAN B7Z9Y9_HUMAN EPPKESMW-YRKLKVFSGTASPSPGEETFEDWLEQVTEIMPIWQ-VSEVEKRRRLLESLR PNMA5_HUMAN PNMA5_HUMAN EPPKESMW-YRKLKVFSGTASPSPGEETFEDWLEQVTEIMPIWQ-VSEVEKRRRLLESLR PNMA3_MOUSE PNMA3_MOUSE QPLLEQML-YRELRVFSGNTISIPGLLAFDSWLEHTTEMLQMWQ-VPEVEKRRRLMECLR B2R5S9_HUMAN B2R5S9_HUMAN QPLLEQML-YRELRVFSGNTISIPGALAFDAWLEHTTEMLQMWQ-VPEGEKRRRLMECLR PNMA3_HUMAN PNMA3_HUMAN QPLLEQML-YRELRVFSGNTISIPGALAFDAWLEHTTEMLQMWQ-VPEGEKRRRLMECLR PNMA2_MOUSE PNMA2_MOUSE RPLLP-VK-YCKMRIFSGSTAAAPEEEPFEVWLEQATEIAKEWP-IPEAEKKRWVAESLR Q5DU13_MOUSE Q5DU13_MOUSE RPLLP-VK-YCKMRIFSGSTAAAPEEEPFEVWLEQATEIAKEWP-IPEAEKKRWVAESLR PNMA2_BOVIN PNMA2_BOVIN QPLLP-MR-YRKLRVFSGSAVPAPEEEPFEVWLEQATEIVKEWP-VAEAEKKRWLMESLR PNMA2_MACFA PNMA2_MACFA QPLLP-MR-YRKLRVFSGSAVPAPEEEPFEVWLEQATEIVKEWP-VTEAEKKRWLAESLR PNMA2_PONAB PNMA2_PONAB QPLLP-MR-YRKLRVFSGSAVPAPEEEPFEVWLEQATEIVKEWP-VTEAEKKRWLAESLR B3KNY9_HUMAN B3KNY9_HUMAN QPLLP-MR-YRKLRVFSGSAVPAPEEESFEVWLEQATEIVKEWP-VTEAEKKRWLAESLR PNMA2_HUMAN PNMA2_HUMAN QPLLP-MR-YRKLRVFSGSAVPAPEEESFEVWLEQATEIVKEWP-VTEAEKKRWLAESLR Q5U5Z3_HUMAN Q5U5Z3_HUMAN QPLLP-MR-YRKLRVFSGSAVPAPEEESFEVWLEQATEIVKEWP-VTEAEKKRWLAESLR PNMA1_BOVIN PNMA1_BOVIN KPLIESIW-YKKLTLFSGRDIPGPGEETFEPWLEHANEVIEEWQ-VSDIEKRRRLMESLR Q6IAP2_HUMAN Q6IAP2_HUMAN QPLVESIW-YKRLTLFSGRDIPGPGEETFDPWLEHTNEVLEEWQ-VSDVEKRRGLMESLR A8K4L5_HUMAN A8K4L5_HUMAN QPLVESIW-YKRLTLFSGRDIPGPGEETFDPWLEHTNEVLEEWQ-VSDVEKRRRLMESLR PNMA1_HUMAN PNMA1_HUMAN QPLVESIW-YKRLTLFSGRDIPGPGEETFDPWLEHTNEVLEEWQ-VSDVEKRRRLMESLR PNMA1_RAT PNMA1_RAT QPLVESIW-YKKLTLFSGRDIPGPGEETFDSWLEHSNEVIEEWQ-VSDIEKRRRLMESLR PNMA1_MOUSE PNMA1_MOUSE QPLVESIW-YKKLTLFSGKDIPGPGEETFDSWLEHSNEIIEEWQ-VSDIEKRRRLMESLR Q3UVU2_MOUSE Q3UVU2_MOUSE QPLVESIW-YKKLTLFSGKDIPGPGEETFDSWLEHSNEIIEEWQ-VSDIEKRRRLMESLR B2RDF6_HUMAN B2RDF6_HUMAN QPALQCLK-YKKLRVFSGRESPEPGEEEFGRWMFHTTQMIKAWQ-VPDVEKRRRLLESLR MOAP1_HUMAN MOAP1_HUMAN QPALQCLK-YKKLRVFSGRESPEPGEEEFGRWMFHTTQMIKAWQ-VPDVEKRRRLLESLR MOAP1_MACFA MOAP1_MACFA QPALQCLK-YKKLRVFSGREPPEPGEEEFGRWMFHTTQMIKAWQ-VPDVEKRRRLLESLR MOAP1_MOUSE MOAP1_MOUSE KPTLQYLR-YKKLSVFSGRDPPGPGEEEFESWMFHTSQVMKTWQ-VSDVEKRRRLIESLR Q5BJV6_RAT Q5BJV6_RAT KPTLQYLR-YKKLSVFSGRDPPGPGEEEFESWMFHTSQVMKTWQ-VSDVEKRRRLMESLR MATCH .. : ** . * *: . .:: * .: *::: : * * CONSENSUS ?P???????Y??L??FSG???P?P?EE?F??W??????????W??V???EK?R?L?ESLR

PN6BL_HUMAN PN6BL_HUMAN GPALEVVSGLLEEDTNLSALDCLAALGQVFRNQDTRMTSRLKFLTCTQGPQEGLFAFVVR PNM6A_HUMAN PNM6A_HUMAN GTALQLVHALLAENPARTAQDCLAALAQVFGDNESQATIRVKCLTAQQQSGERLSAFVLR PNM6B_HUMAN PNM6B_HUMAN GTALQLVHALLAENPARTAQDCLAALAQVFGDNESQATIRVKCLTAQQQSGERLSAFVLR PNMA5_MOUSE PNMA5_MOUSE GSALSIMQALWTSNDSLTVEQCLKALKHIFGNKEDSKVLQFRFLQSSQKPAEKVSDYLLR B7Z9Y9_HUMAN B7Z9Y9_HUMAN GPALSIMRVLQANNDSITVEQCLDALKQIFGDKEDFRASQFRFLQTSPKIGEKVSTFLLR PNMA5_HUMAN PNMA5_HUMAN GPALSIMRVLQANNDSITVEQCLDALKQIFGDKEDFRASQFRFLQTSPKIGEKVSTFLLR PNMA3_MOUSE PNMA3_MOUSE GPALQVVNVLRANNAAITVKECLEALRQVFGSVDNRKIAQLKFCKAYQEPGEKVSSFVVR B2R5S9_HUMAN B2R5S9_HUMAN GPALQVVSGLRASNASITVEECLAALQQVFGPVESHKIAQVKLCKAYQEAGEKVSSFVLR PNMA3_HUMAN PNMA3_HUMAN GPALQVVSGLRASNASITVEECLAALQQVFGPVESHKIAQVKLCKAYQEAGEKVSSFVLR PNMA2_MOUSE PNMA2_MOUSE GPALDLMHIVQADNPSISVGECLEAFKQVFGSTESRRTSQVKYLRTYQQEGEKISAYVLR Q5DU13_MOUSE Q5DU13_MOUSE GPALDLMHIVQADNPSISVGECLEAFKQVFGSTESRRTSQVKYLRTYQQEGEKISAYVLR PNMA2_BOVIN PNMA2_BOVIN GPALDLMHIVQADNPSISVEECLEAFKQVFGNLESRRTSQVKYLKTYQEEGEKVSAYVLR PNMA2_MACFA PNMA2_MACFA GPALDLMHIVQADNPSISVEECLEAFKQVFGSLESRRTAQVRYLKTYQEEGEKVSAYVLR PNMA2_PONAB PNMA2_PONAB GPALDLMHIVQADNPSISVEECLEAFKQVFGSLESRRAAQVRYLKTYQEEGEKVSAYVLR B3KNY9_HUMAN B3KNY9_HUMAN GPALDLMHIVQADNPSISVEECLEAFKQVFGSLESRRTAQVRYLKTYQEEGEKVSAYVLR PNMA2_HUMAN PNMA2_HUMAN GPALDLMHIVQADNPSISVEECLEAFKQVFGSLESRRTAQVRYLKTYQEEGEKVSAYVLR Q5U5Z3_HUMAN Q5U5Z3_HUMAN GPALDLMHIVQADNPSISVEECLEAFKQVFGSLESRRTAQVRYLKTYQEEGEKVSAYVLR PNMA1_BOVIN PNMA1_BOVIN GPAADVIRILKTNNPDITTAECLKALEQVFGSVESSRDVQVRFLNTYQNPGEKLSAYVIR Q6IAP2_HUMAN Q6IAP2_HUMAN GPAADVIRILKSNNPAITTAECLKALEQVFGSVESSRDAQIKFLNTYQNPGEKLSAYVIR A8K4L5_HUMAN A8K4L5_HUMAN GPAADVIRILKSNNPAITTAECLKALEQVFGSVESSRDAQIKFLNTYQNPGEKLSAYVIR PNMA1_HUMAN PNMA1_HUMAN GPAADVIRILKSNNPAITTAECLKALEQVFGSVESSRDAQIKFLNTYQNPGEKLSAYVIR PNMA1_RAT PNMA1_RAT GPAADVIRILKTNNPAITTAECLKALEQVFGSVESSRDAQVRFLNTYQNPGEKLSSYVIR PNMA1_MOUSE PNMA1_MOUSE GPAADVIRILKTNNAAITTAECLKALEQVFGSVESSRDAQVRFLNTYQNPGEKLSSYVIR Q3UVU2_MOUSE Q3UVU2_MOUSE GPAADVIRILKTNNAAITTAECLKALEQVFGSVESSRDAQVRFLNTYQNPGEKLSSYVIR B2RDF6_HUMAN B2RDF6_HUMAN GPALDVIRVLKINNPLITVDECLQALEEVFGVTDNPRELQVKYLTTYQKDEEKLSAYVLR MOAP1_HUMAN MOAP1_HUMAN GPALDVIRVLKINNPLITVDECLQALEEVFGVTDNPRELQVKYLTTYQKDEEKLSAYVLR MOAP1_MACFA MOAP1_MACFA GPALDVIRVLKINNPLITVDECLQALEEVFGVTDNPRELQVKYLTTYQKDEEKLSAYVLR MOAP1_MOUSE MOAP1_MOUSE GPAFEIIRVLKINNPFITVAECLKTLETIFGIIDNPRALQVKYLTTYQKTDEKLSAYVLR Q5BJV6_RAT Q5BJV6_RAT GPAFEIIRVLKINNPFITVAECLKTLETIFGIIDNPRALQVRYLTTYQKSGEKLSAYVLR MATCH *.* .:: : .: :. :** :: :* : :.: * : :::* CONSENSUS GPA??????????N??I????CL?A???VFG????????Q???L???Q???EK?S??V?R

PN6BL_HUMAN PN6BL_HUMAN LEGLLQRAVEKGAVCPALANYLRLQQVLSWA----RPSEALQDTLRGMQLEKRPPGFLGL PNM6A_HUMAN PNM6A_HUMAN LEVLLQKAMEKEALARASADRVRLRQMLTRA----HLTEPLDEALRKLRMAGRSPSFLEM PNM6B_HUMAN PNM6B_HUMAN LEVLLQKAMEKEALARASADRVRLRQMLTRA----HLTEPLDEALRKLRMAGRSPSFLEM PNMA5_MOUSE PNMA5_MOUSE LEPLLQKAVQQSPLSAHSADSIRLKHVLSQV----SMTTGLRGKLSLLDQQGCPPTFLEL B7Z9Y9_HUMAN B7Z9Y9_HUMAN LEPLLQKAVHKSPLSVRSTDMIRLKHLLARV----AMTPALRGKLELLDQRGCPPNFLEL PNMA5_HUMAN PNMA5_HUMAN LEPLLQKAVHKSPLSVRSTDMIRLKHLLARV----AMTPALRGKLELLDQRGCPPNFLEL PNMA3_MOUSE PNMA3_MOUSE LETLLQKALEKNAISRKNVNQTRLKRILGGA----ILSAKLREKLKMLKQRRRPPGFLAL B2R5S9_HUMAN B2R5S9_HUMAN LEPLLQRAVENNVVSRRNVNQTRLKRVLSGA----TLPDKLRDKLKLMKQRRKPPGFLAL PNMA3_HUMAN PNMA3_HUMAN LEPLLQRAVENNVVSRRNVNQTRLKRVLSGA----TLPDKLRDKLKLMKQRRKPPGFLAL PNMA2_MOUSE PNMA2_MOUSE LETLLRRAVEKRAIPRNIADQVRLEQVMAGA----NLGNVLWCRLQELKDQGPLPTFLQL Q5DU13_MOUSE Q5DU13_MOUSE LETLLRRAVEKRAIPRNIADQVRLEQVMAGA----NLGNVLWCRLQELKDQGPLPTFLQL PNMA2_BOVIN PNMA2_BOVIN LETLLRRAVEKRAIPRNIADQIRLEQVMAGA----SLSEVLWCRLRELKDQGRPPSFLQL PNMA2_MACFA PNMA2_MACFA LETLLRRAVEKRAIPRRIADQVRLEQVMAGA----TLNQMLWCRLRELKDQGPPPNFLEL PNMA2_PONAB PNMA2_PONAB LETLLRRAVEKRAIPRRIADQVRLEQVMAGA----TLNQMLWCRLRELKDQGPPPSFLEL B3KNY9_HUMAN B3KNY9_HUMAN LETLLRRAVEKRAIPRRIADQVRLEQVMAGA----TLNQMLWCRLRELKDQGPPPSFLEL PNMA2_HUMAN PNMA2_HUMAN LETLLRRAVEKRAIPRRIADQVRLEQVMAGA----TLNQMLWCRLRELKDQGPPPSFLEL Q5U5Z3_HUMAN Q5U5Z3_HUMAN LETLLRRAVEKRAIPRRIADQVSLEQVMAGA----TLNQMLWCRLRELKDQGPPPSFLEL PNMA1_BOVIN PNMA1_BOVIN LEPLLQKVVEKGAIDKENVNQARLEQVIAGANHSGAIRRQLW---LTGAAEGPAPNLFQL Q6IAP2_HUMAN Q6IAP2_HUMAN LEPLLQKVVEKGAIDKDNVNQARLEQVIAGANHSGAIRRQLW---LTGAGEGPAPNLFQL A8K4L5_HUMAN A8K4L5_HUMAN LEPLLQKVVEKGAIDKDNVNQARLEQVIAGANHSGAIRRQLW---LTGAGEGPAPNLFQL PNMA1_HUMAN PNMA1_HUMAN LEPLLQKVVEKGAIDKDNVNQARLEQVIAGANHSGAIRRQLW---LTGAGEGPAPNLFQL PNMA1_RAT PNMA1_RAT LEPLLQKVVDKGAIDKDNVNQARLEQVIAGANHSGALRRQLW---LTGATEGPAPNLFQL PNMA1_MOUSE PNMA1_MOUSE LEPLLQKVVDKGVIDKDNVNQARLEQVIAGANHSGALRRQLW---LAGAEEGPAPNLFQL Q3UVU2_MOUSE Q3UVU2_MOUSE LEPLLQKVVDKGVIDKDNVNQARLEQVIAGANHSGALRRQLW---LAGAEEGPAPNLFQL B2RDF6_HUMAN B2RDF6_HUMAN LEPLLQKLVQRGAIERDAVNQARLDQVIAGAVHK-TIRREL-----NLPEDGPAPGFLQL MOAP1_HUMAN MOAP1_HUMAN LEPLLQKLVQRGAIERDAVNQARLDQVIAGAVHK-TIRREL-----NLPEDGPAPGFLQL MOAP1_MACFA MOAP1_MACFA LEPLLQKLVQRGAIERDAVNQARLDQVIAGAVHK-TIRREL-----NLPEDGPAPGFLQL MOAP1_MOUSE MOAP1_MOUSE LEPLLQKLVQKGAIEKEVVNQARLDQVIAGAVHK-SVRREL-----GLPEGSPAPGLLQL Q5BJV6_RAT Q5BJV6_RAT LEPLLQKLVQKGAIEKEVVNQARLDQVIAGAIHK-SVRREL-----GLPEGSPAPGLLQL MATCH ** **:: :.. : .: * ::: . * * :: : CONSENSUS LE?LL???V?????????????RL??V???A?????????L?????????????P????L

PN6BL_HUMAN PN6BL_HUMAN LRLIREMEA--------------------------------------------------- PNM6A_HUMAN PNM6A_HUMAN LGLVRESEAWE-ASLARSVRAQTQEGAGARAGAQAVARASTKVEAVPGGPGREPEGLLQA PNM6B_HUMAN PNM6B_HUMAN LGLVRESEAWE-ASLARSVRAQTQEGAGARAGAQAVARASTKVEAVPGGPGREPEGLRQA PNMA5_MOUSE PNMA5_MOUSE MKLTRDEEEWESTVVVEEQEQVRRDSSACEAANEVVTQAEDSREVSTQTTGEEMTSVKRR B7Z9Y9_HUMAN B7Z9Y9_HUMAN MKLTRDEEEWENTEAVMKNKEKPSGRGRGASGRQARAGASVSAPQATVQARSFSDSSPQT PNMA5_HUMAN PNMA5_HUMAN MKLIRDEEEWENTEAVMKNKEKPSGRGRGASGRQARAEASVSAPQATVQARSFSDSSPQT PNMA3_MOUSE PNMA3_MOUSE VKLFREEEEEWEATRGSERSCYEGLELGPSPSNIGSEERELFVPAFGSVLEERPYQGSRR B2R5S9_HUMAN B2R5S9_HUMAN VKLLREEEEWE-ATLGPDRESLEGLEVAPRPPARITGVGAVPLPASGNSFDARPSQGYRR PNMA3_HUMAN PNMA3_HUMAN VKLLREEEEWE-ATLGPDRESLEGLEVAPRPPARITGVGAVPLPASGNSFDARPSQGYRR PNMA2_MOUSE PNMA2_MOUSE MKVIREEEEEEDAYFEQE------------------------------------------ Q5DU13_MOUSE Q5DU13_MOUSE MKVIREEEEEEDAYFEQE------------------------------------------ PNMA2_BOVIN PNMA2_BOVIN MKVIREEEEEE-ATFENE------------------------------------------ PNMA2_MACFA PNMA2_MACFA MKVIREEEEEE-ASFENE------------------------------------------ PNMA2_PONAB PNMA2_PONAB MKVIREEEEEE-ASFENE------------------------------------------ B3KNY9_HUMAN B3KNY9_HUMAN MKVIREEEEEE-ASFENE------------------------------------------ PNMA2_HUMAN PNMA2_HUMAN MKVIREEEEEE-ASFENE------------------------------------------ Q5U5Z3_HUMAN Q5U5Z3_HUMAN MKVIREEEEEE-ASFENE------------------------------------------ PNMA1_BOVIN PNMA1_BOVIN LVQIREEEAKE------------------------------------------------- Q6IAP2_HUMAN Q6IAP2_HUMAN LVQIREEEAKE------------------------------------------------- A8K4L5_HUMAN A8K4L5_HUMAN LVQIREEEAKE------------------------------------------------- PNMA1_HUMAN PNMA1_HUMAN LVQIREEEAKE------------------------------------------------- PNMA1_RAT PNMA1_RAT LVQIREEEAKE------------------------------------------------- PNMA1_MOUSE PNMA1_MOUSE LVQIREEEAKK------------------------------------------------- Q3UVU2_MOUSE Q3UVU2_MOUSE LVQIREEEAKK------------------------------------------------- B2RDF6_HUMAN B2RDF6_HUMAN LVLIKDYEAAE------------------------------------------------- MOAP1_HUMAN MOAP1_HUMAN LVLIKDYEAAE------------------------------------------------- MOAP1_MACFA MOAP1_MACFA LVLIKDYEAAE------------------------------------------------- MOAP1_MOUSE MOAP1_MOUSE LTLIKDKEAEE------------------------------------------------- Q5BJV6_RAT Q5BJV6_RAT LTLIKDKEAAE------------------------------------------------- MATCH : :: * CONSENSUS ????R??E??E?????????????????????????????????????????????????

PN6BL_HUMAN PN6BL_HUMAN ------------------------------------------------------------ PNM6A_HUMAN PNM6A_HUMAN GG---------------------------------------------------------- PNM6B_HUMAN PNM6B_HUMAN GG---------------------------------------------------------- PNMA5_MOUSE PNMA5_MOUSE RLLWRHSAGEEGQRKESGFWAESEPDEQKPYVRAQESGNERGAWAVSHPNPKEIEAQDSQ B7Z9Y9_HUMAN B7Z9Y9_HUMAN IQ---------GG----------------------------------------------- PNMA5_HUMAN PNMA5_HUMAN IQ---------GG----------------------------------------------- PNMA3_MOUSE PNMA3_MOUSE RRHRRRGQHRKGG----------------------------------------------- B2R5S9_HUMAN B2R5S9_HUMAN RR--GRGQHRRGG----------------------------------------------- PNMA3_HUMAN PNMA3_HUMAN RR--GRGQHRRGG----------------------------------------------- PNMA2_MOUSE PNMA2_MOUSE ------------------------------------------------------------ Q5DU13_MOUSE Q5DU13_MOUSE ------------------------------------------------------------ PNMA2_BOVIN PNMA2_BOVIN ------------------------------------------------------------ PNMA2_MACFA PNMA2_MACFA ------------------------------------------------------------ PNMA2_PONAB PNMA2_PONAB ------------------------------------------------------------ B3KNY9_HUMAN B3KNY9_HUMAN ------------------------------------------------------------ PNMA2_HUMAN PNMA2_HUMAN ------------------------------------------------------------ Q5U5Z3_HUMAN Q5U5Z3_HUMAN ------------------------------------------------------------ PNMA1_BOVIN PNMA1_BOVIN ------------------------------------------------------------ Q6IAP2_HUMAN Q6IAP2_HUMAN ------------------------------------------------------------ A8K4L5_HUMAN A8K4L5_HUMAN ------------------------------------------------------------ PNMA1_HUMAN PNMA1_HUMAN ------------------------------------------------------------ PNMA1_RAT PNMA1_RAT ------------------------------------------------------------ PNMA1_MOUSE PNMA1_MOUSE ------------------------------------------------------------ Q3UVU2_MOUSE Q3UVU2_MOUSE ------------------------------------------------------------ B2RDF6_HUMAN B2RDF6_HUMAN ------------------------------------------------------------ MOAP1_HUMAN MOAP1_HUMAN ------------------------------------------------------------ MOAP1_MACFA MOAP1_MACFA ------------------------------------------------------------ MOAP1_MOUSE MOAP1_MOUSE ------------------------------------------------------------ Q5BJV6_RAT Q5BJV6_RAT ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

PN6BL_HUMAN PN6BL_HUMAN ------------------------------------------------------------ PNM6A_HUMAN PNM6A_HUMAN -------------------------------------------QEAEELLQEGL------ PNM6B_HUMAN PNM6B_HUMAN -------------------------------------------QEAEELLQEGL------ PNMA5_MOUSE PNMA5_MOUSE EFLPVAGNRDTLTKSWGSPDKGTGDMSVAEGQQGQGKAPNFLLARNDPNKQEQIPHSSVT B7Z9Y9_HUMAN B7Z9Y9_HUMAN --LPPLVKRRRLLGSESTRGEDHGQATYPKAENQTPGREGPQAAGEELGNEAGA------ PNMA5_HUMAN PNMA5_HUMAN --LPPLVKRRRLLGSESTRGEDHGQATYPKAENQTPGREGPQAAGEELGNEAGA------ PNMA3_MOUSE PNMA3_MOUSE --VPRDDSQGTRKQNYDTFCYSCGEDGHIRVHCFNPSNRTLVKQKRQAAMEKGN------ B2R5S9_HUMAN B2R5S9_HUMAN --VARAGSRGSRKRKRHTLCYSCGEDGHIRVQCINPSNLLLVKQKKQAAVESGN------ PNMA3_HUMAN PNMA3_HUMAN --VARAGSRGSRKRKRHTFCYSCGEDGHIRVQCINPSNLLLVKQKKQAAVESGN------ PNMA2_MOUSE PNMA2_MOUSE -------------------------------------------SREEPGEREGS------ Q5DU13_MOUSE Q5DU13_MOUSE -------------------------------------------SREEPGEREGS------ PNMA2_BOVIN PNMA2_BOVIN -------------------------------------------NTEEPEGGDGY------ PNMA2_MACFA PNMA2_MACFA -------------------------------------------SIEEPEEGDGY------ PNMA2_PONAB PNMA2_PONAB -------------------------------------------SIEEPEEGDGY------ B3KNY9_HUMAN B3KNY9_HUMAN -------------------------------------------SIEEPEERDGY------ PNMA2_HUMAN PNMA2_HUMAN -------------------------------------------SIEEPEERDGY------ Q5U5Z3_HUMAN Q5U5Z3_HUMAN -------------------------------------------SIEEPEERDGY------ PNMA1_BOVIN PNMA1_BOVIN ---------------------------------------------EEAAAEAAL------ Q6IAP2_HUMAN Q6IAP2_HUMAN ---------------------------------------------EEEEAEATL------ A8K4L5_HUMAN A8K4L5_HUMAN ---------------------------------------------EEEEAEATL------ PNMA1_HUMAN PNMA1_HUMAN ---------------------------------------------EEEEAEATL------ PNMA1_RAT PNMA1_RAT ---------------------------------------------EEEEAEAAL------ PNMA1_MOUSE PNMA1_MOUSE ---------------------------------------------EEEEAEAAL------ Q3UVU2_MOUSE Q3UVU2_MOUSE ---------------------------------------------EEEEAEAAL------ B2RDF6_HUMAN B2RDF6_HUMAN -------------------------------------------------EEEAL------ MOAP1_HUMAN MOAP1_HUMAN -------------------------------------------------EEEAL------ MOAP1_MACFA MOAP1_MACFA -------------------------------------------------EEEAL------ MOAP1_MOUSE MOAP1_MOUSE --------------------------------------------------EEVL------ Q5BJV6_RAT Q5BJV6_RAT --------------------------------------------------EEVL------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

PN6BL_HUMAN PN6BL_HUMAN ------------------------------------------------------------ PNM6A_HUMAN PNM6A_HUMAN -----------KPVL--------------------------------------------- PNM6B_HUMAN PNM6B_HUMAN -----------KPVL--------------------------------------------- PNMA5_MOUSE PNMA5_MOUSE TKWQDRGECQRLKWGASMITRPQGNPDRSWDTSGSQDGEDGCSELRMPTGTEAAQGVEEP B7Z9Y9_HUMAN B7Z9Y9_HUMAN -----------GAMS--------------------------------------------- PNMA5_HUMAN PNMA5_HUMAN -----------GAMS--------------------------------------------- PNMA3_MOUSE PNMA3_MOUSE -----------RSWA--------------------------------------------- B2R5S9_HUMAN B2R5S9_HUMAN -----------GNWA--------------------------------------------- PNMA3_HUMAN PNMA3_HUMAN -----------GNWA--------------------------------------------- PNMA2_MOUSE PNMA2_MOUSE -----------GCWN--------------------------------------------- Q5DU13_MOUSE Q5DU13_MOUSE -----------GCWN--------------------------------------------- PNMA2_BOVIN PNMA2_BOVIN -----------GHWG--------------------------------------------- PNMA2_MACFA PNMA2_MACFA -----------GGWN--------------------------------------------- PNMA2_PONAB PNMA2_PONAB -----------GRWN--------------------------------------------- B3KNY9_HUMAN B3KNY9_HUMAN -----------GRWN--------------------------------------------- PNMA2_HUMAN PNMA2_HUMAN -----------GRWN--------------------------------------------- Q5U5Z3_HUMAN Q5U5Z3_HUMAN -----------GRWN--------------------------------------------- PNMA1_BOVIN PNMA1_BOVIN -----------LQLG--------------------------------------------- Q6IAP2_HUMAN Q6IAP2_HUMAN -----------LQLG--------------------------------------------- A8K4L5_HUMAN A8K4L5_HUMAN -----------LQLG--------------------------------------------- PNMA1_HUMAN PNMA1_HUMAN -----------LQLG--------------------------------------------- PNMA1_RAT PNMA1_RAT -----------LQLG--------------------------------------------- PNMA1_MOUSE PNMA1_MOUSE -----------LQLG--------------------------------------------- Q3UVU2_MOUSE Q3UVU2_MOUSE -----------LQLG--------------------------------------------- B2RDF6_HUMAN B2RDF6_HUMAN -----------LQAI--------------------------------------------- MOAP1_HUMAN MOAP1_HUMAN -----------LQAI--------------------------------------------- MOAP1_MACFA MOAP1_MACFA -----------LQEV--------------------------------------------- MOAP1_MOUSE MOAP1_MOUSE -----------LQAE--------------------------------------------- Q5BJV6_RAT Q5BJV6_RAT -----------LQAE--------------------------------------------- MATCH CONSENSUS ????????????????????????????????????????????????????????????

PN6BL_HUMAN PN6BL_HUMAN -------------------------------------------------------- PNM6A_HUMAN PNM6A_HUMAN ---------------------------------------------EECDN------ PNM6B_HUMAN PNM6B_HUMAN ---------------------------------------------EECDN------ PNMA5_MOUSE PNMA5_MOUSE ATGLSWAEDTSAWEQARLGRETVPRRGGRRIQPVFRIIYTALGEPHEGSTLESFRE B7Z9Y9_HUMAN B7Z9Y9_HUMAN ---------------------------------------------HPKPWET---- PNMA5_HUMAN PNMA5_HUMAN ---------------------------------------------HPKPWET---- PNMA3_MOUSE PNMA3_MOUSE ---------------------------------------------WEKSHPKPKTK B2R5S9_HUMAN B2R5S9_HUMAN ---------------------------------------------WDKSHPKSKAK PNMA3_HUMAN PNMA3_HUMAN ---------------------------------------------WDKSHPKSKAK PNMA2_MOUSE PNMA2_MOUSE ---------------------------------------------NSRNN------ Q5DU13_MOUSE Q5DU13_MOUSE ---------------------------------------------NSRNN------ PNMA2_BOVIN PNMA2_BOVIN ---------------------------------------------NEAND------ PNMA2_MACFA PNMA2_MACFA ---------------------------------------------HEGDD------ PNMA2_PONAB PNMA2_PONAB ---------------------------------------------HEGDD------ B3KNY9_HUMAN B3KNY9_HUMAN ---------------------------------------------HEGDD------ PNMA2_HUMAN PNMA2_HUMAN ---------------------------------------------HEGDD------ Q5U5Z3_HUMAN Q5U5Z3_HUMAN ---------------------------------------------HEGDD------ PNMA1_BOVIN PNMA1_BOVIN ---------------------------------------------LEGHF------ Q6IAP2_HUMAN Q6IAP2_HUMAN ---------------------------------------------LEGHF------ A8K4L5_HUMAN A8K4L5_HUMAN ---------------------------------------------LEGHF------ PNMA1_HUMAN PNMA1_HUMAN ---------------------------------------------LEGHF------ PNMA1_RAT PNMA1_RAT ---------------------------------------------LEGHF------ PNMA1_MOUSE PNMA1_MOUSE ---------------------------------------------LEGHF------ Q3UVU2_MOUSE Q3UVU2_MOUSE ---------------------------------------------LEGHF------ B2RDF6_HUMAN B2RDF6_HUMAN ---------------------------------------------LEGNFT----- MOAP1_HUMAN MOAP1_HUMAN ---------------------------------------------LEGNFT----- MOAP1_MACFA MOAP1_MACFA ---------------------------------------------LEGHFT----- MOAP1_MOUSE MOAP1_MOUSE ---------------------------------------------LEGYCT----- Q5BJV6_RAT Q5BJV6_RAT ---------------------------------------------LEGHFT----- MATCH CONSENSUS ????????????????????????????????????????????????????????


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