Alignment of the gene Family HBG052618 of HOVERGEN

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Threshold: 50% 80% 100%
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Isoforms are ON
Q5U4N4_XENLA Q5U4N4_XENLA ------------------------------------------------------------ B7ZWM3_MOUSE B7ZWM3_MOUSE PFAKRIVEPQWLCRQRRPAPGPDEDTSGGSVEPPPPLQPPGRR--EEAEAPEPEEPPRVP B2RXX7_MOUSE B2RXX7_MOUSE PFAKRIVEPQWLCRQRRPAPGPDEDTSGGSVEPPPPLQPPGRR--EEAEAPEPEEPPRVP B1AV60_MOUSE B1AV60_MOUSE PFAKRIVEPQWLCRQRRPAPGPDEDTSGGSVEPPPPLQPPGRR--EEAEAPEPEEPPRVP B9EJX2_MOUSE B9EJX2_MOUSE PFAKRIVEPQWLCRQRRPAPGPDEDTSGGSVEPPPPLQPPGRR--EEAEAPEPEEPPRVP Q5RE45_PONAB Q5RE45_PONAB ------------------------------------------------------------ B7Z7S2_HUMAN B7Z7S2_HUMAN PFAKRIVEPQWLCRQRRPAPGPAVDASGGSAEPPPPLQPPGRRDLDEVEAPGPEEPARAV B7ZVX8_HUMAN B7ZVX8_HUMAN PFAKRIVEPQWLCRQRRPAPGPAVDASGGSAEPPPPLQPPGRRDLDEVEAPGPEEPARAV NHS_HUMAN NHS_HUMAN PFAKRIVEPQWLCRQRRPAPGPAVDASGGSAEPPPPLQPPGRRDLDEVEAPGPEEPARAV MATCH CONSENSUS ????????????????????????????????????????????????????????????

Q5U4N4_XENLA Q5U4N4_XENLA ------------------------------------------------------------ B7ZWM3_MOUSE B7ZWM3_MOUSE PAPLPLPPLPPSLPAPAEQDQQPPSEAREAGEESVAGVSEAASAPGE-TSEASAEAVLLM B2RXX7_MOUSE B2RXX7_MOUSE PAPLPLPPLPPSLPAPAEQDQQPPSEAREAGEESVAGVSEAASAPGE-TSEASAEAVLLM B1AV60_MOUSE B1AV60_MOUSE PAPLPLPPLPPSLPAPAEQDQQPPSEAREAGEESVAGVSEAASAPGE-TSEASAEAVLLM B9EJX2_MOUSE B9EJX2_MOUSE PAPLPLPPLPPSLPAPAEQDQQPPSEAREAGEESVAGVSEAASAPGE-TSEASAEAVLLM Q5RE45_PONAB Q5RE45_PONAB ------------------------------------------------------------ B7Z7S2_HUMAN B7Z7S2_HUMAN PAPSGLPPPPPPLPAPADQTQPPHGEASVAGEESTAGIPEAAPAAGEASSAAAAAAVLLM B7ZVX8_HUMAN B7ZVX8_HUMAN PAPSGLPPPPPPLPAPADQTQPPHGEASVAGEESTAGIPEAAPAAGEASSAAAAAAVLLM NHS_HUMAN NHS_HUMAN PAPSGLPPPPPPLPAPADQTQPPHGEASVAGEESTAGIPEAAPAAGEASSAAAAAAVLLM MATCH CONSENSUS ????????????????????????????????????????????????????????????

Q5U4N4_XENLA Q5U4N4_XENLA ---------------------------------------MQKIYA--------------- B7ZWM3_MOUSE B7ZWM3_MOUSE LDLCAVSNAALARVLRQLSDVARHACSLFQELESDIQLTHRRVWALQGKLGSVQRVLSTL B2RXX7_MOUSE B2RXX7_MOUSE LDLCAVSNAALARVLRQLSDVARHACSLFQELESDIQLTHRRVWALQGKLGSVQRVLSTL B1AV60_MOUSE B1AV60_MOUSE LDLCAVSNAALARVLRQLSDVARHACSLFQELESDIQLTHRRVWALQGKLGSVQRVLSTL B9EJX2_MOUSE B9EJX2_MOUSE LDLCAVSNAALARVLRQLSDVARHACSLFQELESDIQLTHRRVWALQGKLGSVQRVLSTL Q5RE45_PONAB Q5RE45_PONAB ------------------------------------------------------------ B7Z7S2_HUMAN B7Z7S2_HUMAN LDLCAVSNAALARVLRQLSDVARHACSLFQELESDIQLTHRRVWALQGKLGGVQRVLSTL B7ZVX8_HUMAN B7ZVX8_HUMAN LDLCAVSNAALARVLRQLSDVARHACSLFQELESDIQLTHRRVWALQGKLGGVQRVLSTL NHS_HUMAN NHS_HUMAN LDLCAVSNAALARVLRQLSDVARHACSLFQELESDIQLTHRRVWALQGKLGGVQRVLSTL MATCH CONSENSUS ????????????????????????????????????????????A???????????????

Q5U4N4_XENLA Q5U4N4_XENLA -----AKAVSNLDAESKLDVFYKSSWHQQRNIFLPITRPICVEELHRHAKQSLRSMRKEQ B7ZWM3_MOUSE B7ZWM3_MOUSE DPKQEAVPVSNLDIESKLSVYYRAPWHQQRNIFLQATRPPCVEELHRHARQSLQALRREH B2RXX7_MOUSE B2RXX7_MOUSE DPKQEAVPVSNLDIESKLSVYYRAPWHQQRNIFLPATRPPCVEELHRHARQSLQALRREH B1AV60_MOUSE B1AV60_MOUSE DPKQEAVPVSNLDIESKLSVYYRAPWHQQRNIFLPATRPPCVEELHRHARQSLQALRREH B9EJX2_MOUSE B9EJX2_MOUSE DPKQEAVPVSNLDIESKLSVYYRAPWHQQRNIFLPATRPPCVEELHRHARQSLQALRREH Q5RE45_PONAB Q5RE45_PONAB ------------------------------------------------------------ B7Z7S2_HUMAN B7Z7S2_HUMAN DPKQEAVPVSNLDIESKLSVYYRAPWHQQRNIFLPATRPPCVEELHRHARQSLQALRREH B7ZVX8_HUMAN B7ZVX8_HUMAN DPKQEAVPVSNLDIESKLSVYYRAPWHQQRNIFLPATRPPCVEELHRHARQSLQALRREH NHS_HUMAN NHS_HUMAN DPKQEAVPVSNLDIESKLSVYYRAPWHQQRNIFLPATRPPCVEELHRHARQSLQALRREH MATCH CONSENSUS ?????A??VSNLD?ESKL?V?Y???WHQQRNIFL??TRP?CVEELHRHA?QSL???R?E?

Q5U4N4_XENLA Q5U4N4_XENLA RIRADNRERRFQGSI-FTAPPLPTYPAVNNLKRQEIKERHVVQFNRTRSHSPTECCHLTP B7ZWM3_MOUSE B7ZWM3_MOUSE RSRSDRREQRAAAPLPIAAPPLPAYPPAHSQRRREAKDRHFLTFNSTRSPSPTECCHMAP B2RXX7_MOUSE B2RXX7_MOUSE RSRSDRREQRAAAPLPIAAPPLPAYPPAHSQRRREAKDRHFLTFNSTRSPSPTECCHMAP B1AV60_MOUSE B1AV60_MOUSE RSRSDRREQRAAAPLPIAAPPLPAYPPAHSQRRREAKDRHFLTFNSTRSPSPTECCHMAP B9EJX2_MOUSE B9EJX2_MOUSE RSRSDRREQRAAAPLPIAAPPLPAYPPAHSQRRREAKDRHFLT----------------- Q5RE45_PONAB Q5RE45_PONAB ---------------------------------------------------------MTP B7Z7S2_HUMAN B7Z7S2_HUMAN RSRSDRREQRAAAPLSIAAPPLPAYPPAHSQRRREFKDRHFLTFNSTRSPSPTECCHMTP B7ZVX8_HUMAN B7ZVX8_HUMAN RSRSDRREQRAAAPLSIAAPPLPAYPPAHSQRRREFKDRHFLTFNSTRSPSPTECCHMTP NHS_HUMAN NHS_HUMAN RSRSDRREQRAAAPLSIAAPPLPAYPPAHSQRRREFKDRHFLT----------------- MATCH CONSENSUS R?R?D?RE?R????????APPLP?YP??????R?E?K?RH????????????????????

Q5U4N4_XENLA Q5U4N4_XENLA WSRKAHAPQEED-DINIGQRPKNPIPNVPSTLDKQTNWNKALPLPTPDEKMKQESQVITS B7ZWM3_MOUSE B7ZWM3_MOUSE WSRKSHSPEDEDTDAMLGQRPKNPIHNVPSTLDKQTNWNKALPLPTPEEKMKQDAQVISS B2RXX7_MOUSE B2RXX7_MOUSE WSRKSHSPEDEDTDAMLGQRPKNPIHNVPSTLDKQTNWNKALPLPTPEEKMKQDAQVISS B1AV60_MOUSE B1AV60_MOUSE WSRKSHSPEDEDTDAMLGQRPKNPIHNVPSTLDKQTNWNKALPLPTPEEKMKQDAQVISS B9EJX2_MOUSE B9EJX2_MOUSE ----SHSPEDEDTDAMLGQRPKNPIHNVPSTLDKQTNWNKALPLPTPEEKMKQDAQVISS Q5RE45_PONAB Q5RE45_PONAB WSRKSHPPEDEDTDVMLGQRPKNPIHNIPSTLDKQTNWSKALPLPTPEEKMKQDAQVISS B7Z7S2_HUMAN B7Z7S2_HUMAN WSRKSHPPEDEDTDVMLGQRPKNPIHNIPSTLDKQTNWSKALPLPTPEEKMKQDAQVISS B7ZVX8_HUMAN B7ZVX8_HUMAN WSRKSHPPEDEDTDVMLGQRPKNPIHNIPSTLDKQTNWSKALPLPTPEEKMKQDAQVISS NHS_HUMAN NHS_HUMAN ----SHPPEDEDTDVMLGQRPKNPIHNIPSTLDKQTNWSKALPLPTPEEKMKQDAQVISS MATCH :*.*::** * :******** *:**********.********:*****::***:* CONSENSUS ????SH?PEDEDTD?MLGQRPKNPIHN?PSTLDKQTNW?KALPLPTPEEKMKQDAQVISS

Q5U4N4_XENLA Q5U4N4_XENLA CIIPINVSGVGFDREASIRCSLVHSQSVLQRRRKLRRRKTISGIPRRVQQEIDSDESPVA B7ZWM3_MOUSE B7ZWM3_MOUSE CIIPINVTGVGFDREASIRCSLVHSQSVLQRRRKLRRRKTISGIPRRVQQEIDSDESPVA B2RXX7_MOUSE B2RXX7_MOUSE CIIPINVTGVGFDREASIRCSLVHSQSVLQRRRKLRRRKTISGIPRRVQQEIDSDESPVA B1AV60_MOUSE B1AV60_MOUSE CIIPINVTGVGFDREASIRCSLVHSQSVLQRRRKLRRRKTISGIPRRVQQEIDSDESPVA B9EJX2_MOUSE B9EJX2_MOUSE CIIPINVTGVGFDREASIRCSLVHSQSVLQRRRKLRRRKTISGIPRRVQQEIDSDESPVA Q5RE45_PONAB Q5RE45_PONAB CIIPINVTGVGFDREASIRCSLVHSQSVLQRRRKLRRRKTISGIPRRVQQEIDSDESPVA B7Z7S2_HUMAN B7Z7S2_HUMAN CIIPINVTGVGFDREASIRCSLVHSQSVLQRRRKLRRRKTISGIPRRVQQEIDSDESPVA B7ZVX8_HUMAN B7ZVX8_HUMAN CIIPINVTGVGFDREASIRCSLVHSQSVLQRRRKLRRRKTISGIPRRVQQEIDSDESPVA NHS_HUMAN NHS_HUMAN CIIPINVTGVGFDREASIRCSLVHSQSVLQRRRKLRRRKTISGIPRRVQQEIDSDESPVA MATCH *******:**************************************************** CONSENSUS CIIPINVTGVGFDREASIRCSLVHSQSVLQRRRKLRRRKTISGIPRRVQQEIDSDESPVA

Q5U4N4_XENLA Q5U4N4_XENLA RDRNVIVHANPELASSANRRSGTRDTECQTDDILIAAPSRRRIRAQRGQGIAASLSHSAG B7ZWM3_MOUSE B7ZWM3_MOUSE RERNVIVHTNPDPSNTVNRRSGTRDSECQTEDILIAAPSRRRIRAQRGQSIAASLSHSAG B2RXX7_MOUSE B2RXX7_MOUSE RERNVIVHTNPDPSNTVNRRSGTRDSECQTEDILIAAPSRRRIRAQRGQSIAASLSHSAG B1AV60_MOUSE B1AV60_MOUSE RERNVIVHTNPDPSNTVNRRSGTRDSECQTEDILIAAPSRRRIRAQRGQSIAASLSHSAG B9EJX2_MOUSE B9EJX2_MOUSE RERNVIVHTNPDPSNTVNRRSGTRDSECQTEDILIAAPSRRRIRAQRGQSIAASLSHSAG Q5RE45_PONAB Q5RE45_PONAB RERNVIVHTNPDPSNTVNRISGTRDSECQTEDILIAAPSRRRIRAQRGQSIAASLSHSAG B7Z7S2_HUMAN B7Z7S2_HUMAN RERNVIVHTNPDPSNTVNRISGTRDSECQTEDILIAAPSRRRIRAQRGQSIAASLSHSAG B7ZVX8_HUMAN B7ZVX8_HUMAN RERNVIVHTNPDPSNTVNRISGTRDSECQTEDILIAAPSRRRIRAQRGQSIAASLSHSAG NHS_HUMAN NHS_HUMAN RERNVIVHTNPDPSNTVNRISGTRDSECQTEDILIAAPSRRRIRAQRGQSIAASLSHSAG MATCH *:******:**: :.:.** *****:****:******************.********** CONSENSUS RERNVIVHTNPDPSNTVNR?SGTRDSECQTEDILIAAPSRRRIRAQRGQSIAASLSHSAG

Q5U4N4_XENLA Q5U4N4_XENLA NIAALTESGDQMFKNTVSSRIRSRSLPRESARESN-DHDCSAQSSTYEE-DCYMPCTERI B7ZWM3_MOUSE B7ZWM3_MOUSE NISALADKGDTMFTPVVSSRTRSRSLPREGNRGGDAEPKVGAKPSAFEEGERFVGDHERT B2RXX7_MOUSE B2RXX7_MOUSE NISALADKGDTMFTPVVSSRTRSRSLPREGNRGGDAEPKVGAKPSAFEEGERFVGDHERT B1AV60_MOUSE B1AV60_MOUSE NISALADKGDTMFTPVVSSRTRSRSLPREGNRGGDAEPKVGAKPSAFEEGERFVGDHERT B9EJX2_MOUSE B9EJX2_MOUSE NISALADKGDTMFTPVVSSRTRSRSLPREGNRGGDAEPKVGAKPSAFEEGERFVGDHERT Q5RE45_PONAB Q5RE45_PONAB NISALADKGDTMFTPAVSSRTRSRSLPREGNRGGDAEPKVGAKPSAYEEGESFVGDHERT B7Z7S2_HUMAN B7Z7S2_HUMAN NISALADKGDTMFTPAVSSRTRSRSLPREGNRGGDAEPKVGAKPSAYEEGESFVGDHERT B7ZVX8_HUMAN B7ZVX8_HUMAN NISALADKGDTMFTPAVSSRTRSRSLPREGNRGGDAEPKVGAKPSAYEEGESFVGDHERT NHS_HUMAN NHS_HUMAN NISALADKGDTMFTPAVSSRTRSRSLPREGNRGGDAEPKVGAKPSAYEEGESFVGDHERT MATCH **:**::.** **. .**** ********. * .: : . .*:.*::** : :: ** CONSENSUS NISALADKGDTMFTP?VSSRTRSRSLPREGNRGGDAEPKVGAKPSA?EEGE?FVGDHERT

Q5U4N4_XENLA Q5U4N4_XENLA LKKDKDSLTSQESPDHQP-LGLTYSQHRHSPQLHLNERGRSRLSRM-ADSGSCDISSNSD B7ZWM3_MOUSE B7ZWM3_MOUSE PNDCSEAPSSPSTQEHQPALGLACSQHLHSPQQKLSERGRSRLSRMAADSGSCDISSNSD B2RXX7_MOUSE B2RXX7_MOUSE PNDCSEAPSSPSTQEHQPALGLACSQHLHSPQQKLSERGRSRLSRMAADSGSCDISSNSD B1AV60_MOUSE B1AV60_MOUSE PNDCSEAPSSPSTQEHQPALGLACSQHLHSPQQKLSERGRSRLSRMAADSGSCDISSNSD B9EJX2_MOUSE B9EJX2_MOUSE PNDCSEAPSSPSTQEHQPALGLACSQHLHSPQQKLSERGRSRLSRMAADSGSCDISSNSD Q5RE45_PONAB Q5RE45_PONAB PNDFSEAPSSPSAQDHQPTLGLACSQHLHSPQHKLSERGRSRLSRMAADSGSCDISSNSD B7Z7S2_HUMAN B7Z7S2_HUMAN PNDFSEAPSSPSAQDHQPTLGLACSQHLHSPQHKLSERGRSRLSRMAADSGSCDISSNSD B7ZVX8_HUMAN B7ZVX8_HUMAN PNDFSEAPSSPSAQDHQPTLGLACSQHLHSPQHKLSERGRSRLSRMAADSGSCDISSNSD NHS_HUMAN NHS_HUMAN PNDFSEAPSSPSAQDHQPTLGLACSQHLHSPQHKLSERGRSRLSRMAADSGSCDISSNSD MATCH :. .:: :* .: :*** ***: *** **** :*.********** ************* CONSENSUS PND?SEAPSSPS?Q?HQP?LGLACSQHLHSPQ?KLSERGRSRLSRMAADSGSCDISSNSD

Q5U4N4_XENLA Q5U4N4_XENLA TFGSPVHSISAAGVLLSTHIDQKDDHQSSSGNWSGSSSTCPSQTSETIPPAASPPLTGSS B7ZWM3_MOUSE B7ZWM3_MOUSE TFGSPIHCISTASVLLSSHMDQKEDHQSSSGNWSGSSSTCPSQTSETIPPAASPPLTGSS B2RXX7_MOUSE B2RXX7_MOUSE TFGSPVHCISTASVLLSSHMDQKEDHQSSSGNWSGSSSTCPSQTSETIPPAASPPLTGSS B1AV60_MOUSE B1AV60_MOUSE TFGSPVHCISTASVLLSSHMDQKEDHQSSSGNWSGSSSTCPSQTSETIPPAASPPLTGSS B9EJX2_MOUSE B9EJX2_MOUSE TFGSPVHCISTASVLLSSHMDQKEDHQSSSGNWSGSSSTCPSQTSETIPPAASPPLTGSS Q5RE45_PONAB Q5RE45_PONAB TFGSPIHCISTAGVLLSSHMDQKDDHQSSSGNWSGSSSTCPSQTSETIPPAASPPLTGSS B7Z7S2_HUMAN B7Z7S2_HUMAN TFGSPIHCISTAGVLLSSHMDQKDGHQSSSGNWSGSSSTCPSQTSETIPPAASPPLTGSS B7ZVX8_HUMAN B7ZVX8_HUMAN TFGSPIHCISTAGVLLSSHMDQKDDHQSSSGNWSGSSSTCPSQTSETIPPAASPPLTGSS NHS_HUMAN NHS_HUMAN TFGSPIHCISTAGVLLSSHMDQKDDHQSSSGNWSGSSSTCPSQTSETIPPAASPPLTGSS MATCH *****:*.**:*.****:*:***:.*********************************** CONSENSUS TFGSP?HCISTA?VLLSSHMDQK?DHQSSSGNWSGSSSTCPSQTSETIPPAASPPLTGSS

Q5U4N4_XENLA Q5U4N4_XENLA HCDSELSLNTAPNAGEDSNVFITEQYSDDHIDSIRGHRASSFTSTVADLLDDP-NSNTSD B7ZWM3_MOUSE B7ZWM3_MOUSE HCDSELSLNTAPNANEDASVFVTEQY-NDHLDKVRGHRTNSFTSTVADLLDDPNNSNTSD B2RXX7_MOUSE B2RXX7_MOUSE HCDSELSLNTAPNANEDASVFVTEQY-NDHLDKVRGHRTNSFTSTVADLLDDPNNSNTSD B1AV60_MOUSE B1AV60_MOUSE HCDSELSLNTAPNANEDASVFVTEQY-NDHLDKVRGHRTNSFTSTVADLLDDPNNSNTSD B9EJX2_MOUSE B9EJX2_MOUSE HCDSELSLNTAPNANEDASVFVTEQY-NDHLDKVRGHRTNSFTSTVADLLDDPNNSNTSD Q5RE45_PONAB Q5RE45_PONAB HCDSELSLNTAPHANEDASVFVTEQY-NDHLDKVRGHRANSFTSTVADLLDDPNNSNTSD B7Z7S2_HUMAN B7Z7S2_HUMAN HCDSELSLNTAPHANEDASVFVTEQY-NDHLDKVRGHRANSFTSTVADLLDDPNNSNTSD B7ZVX8_HUMAN B7ZVX8_HUMAN HCDSELSLNTAPHANEDASVFVTEQY-NDHLDKVRGHRANSFTSTVADLLDDPNNSNTSD NHS_HUMAN NHS_HUMAN HCDSELSLNTAPHANEDASVFVTEQY-NDHLDKVRGHRANSFTSTVADLLDDPNNSNTSD MATCH ************:*.**:.**:**** :**:*.:****:.************* ****** CONSENSUS HCDSELSLNTAP?ANEDASVFVTEQY?NDHLDKVRGHR?NSFTSTVADLLDDPNNSNTSD

Q5U4N4_XENLA Q5U4N4_XENLA SEWNYLHHHHDASCHQDFSPQHLKTDRLACPSFTSMGTYDSFLEKPASEKADTGSHFSVD B7ZWM3_MOUSE B7ZWM3_MOUSE SEWNYLHHHHDASCRQDFSPERPKADSLGCPSFTSMGTYDSFLEKSPSDKADTSSHFSVD B2RXX7_MOUSE B2RXX7_MOUSE SEWNYLHHHHDASCRQDFSPERPKADSLGCPSFTSMGTYDSFLEKSPSDKADTSSHFSVD B1AV60_MOUSE B1AV60_MOUSE SEWNYLHHHHDASCRQDFSPERPKADSLGCPSFTSMGTYDSFLEKSPSDKADTSSHFSVD B9EJX2_MOUSE B9EJX2_MOUSE SEWNYLHHHHDASCRQDFSPERPKADSLGCPSFTSMGTYDSFLEKSPSDKADTSSHFSVD Q5RE45_PONAB Q5RE45_PONAB SEWNYLHHHHDASCRQDFSPERPKADSLGCPSFTSMATYDSFLEKSPSDKADTSSHFSVD B7Z7S2_HUMAN B7Z7S2_HUMAN SEWNYLHHHHDASCRQDFSPERPKADSLGCPSFTSMATYDSFLEKSPSDKADTSSHFSVD B7ZVX8_HUMAN B7ZVX8_HUMAN SEWNYLHHHHDASCRQDFSPERPKADSLGCPSFTSMATYDSFLEKSPSDKADTSSHFSVD NHS_HUMAN NHS_HUMAN SEWNYLHHHHDASCRQDFSPERPKADSLGCPSFTSMATYDSFLEKSPSDKADTSSHFSVD MATCH **************:*****:: *:* *.*******.********..*:****.****** CONSENSUS SEWNYLHHHHDASCRQDFSPERPKADSLGCPSFTSM?TYDSFLEKSPSDKADTSSHFSVD

Q5U4N4_XENLA Q5U4N4_XENLA TEGYYTSMHFDCGLNTGRSYIYNYAPTGSERDQGRGISSMNTDNAWQCYMDQENEGNQNI B7ZWM3_MOUSE B7ZWM3_MOUSE TEGYYTSMHFDCGLKGNKTYVCHYAGLGPENGQGVGVPPALPDCAWQEYLDHRRQGRPSI B2RXX7_MOUSE B2RXX7_MOUSE TEGYYTSMHFDCGLKGNKTYVCHYAGLGPENGQGVGVPPALPDCAWQEYLDHRRQGRPSI B1AV60_MOUSE B1AV60_MOUSE TEGYYTSMHFDCGLKGNKTYVCHYAGLGPENGQGVGVPPALPDCAWQEYLDHRRQGRPSI B9EJX2_MOUSE B9EJX2_MOUSE TEGYYTSMHFDCGLKGNKTYVCHYAGLGPENGQGVGVPPALPDCAWQEYLDHRRQGRPSI Q5RE45_PONAB Q5RE45_PONAB TEGYYTSMHFDCGLKGNKSYVCHYAALGPENGQGVGASPGLPDCAWQDYLDHKRQGRPSI B7Z7S2_HUMAN B7Z7S2_HUMAN TEGYYTSMHFDCGLKGNKSYVCHYAALGPENGQGVGASPGLPDCAWQDYLDHKRQGRPSI B7ZVX8_HUMAN B7ZVX8_HUMAN TEGYYTSMHFDCGLKGNKSYVCHYAALGPENGQGVGASPGLPDCAWQDYLDHKRQGRPSI NHS_HUMAN NHS_HUMAN TEGYYTSMHFDCGLKGNKSYVCHYAALGPENGQGVGASPGLPDCAWQDYLDHKRQGRPSI MATCH **************: .::*: :** *.*..** * .. .* *** *:*:..:*. .* CONSENSUS TEGYYTSMHFDCGLKGNK?YVCHYA?LGPENGQGVG??P?LPDCAWQ?YLDH?RQGRPSI

Q5U4N4_XENLA Q5U4N4_XENLA SFKKPKARPTPPKRSSSLRKSDNNTDILEKKEPKIVCGQQQVIHSSREMKLPLEMSNIPS B7ZWM3_MOUSE B7ZWM3_MOUSE SFRKPKAKPTPPKRSSSLRKSDGNADISEKKEPKISSGQHLP-HSSREMKLPLDFSNTPS B2RXX7_MOUSE B2RXX7_MOUSE SFRKPKAKPTPPKRSSSLRKSDGNADISEKKEPKISSGQHLP-HSSREMKLPLDFSNTPS B1AV60_MOUSE B1AV60_MOUSE SFRKPKAKPTPPKRSSSLRKSDGNADISEKKEPKISSGQHLP-HSSREMKLPLDFSNTPS B9EJX2_MOUSE B9EJX2_MOUSE SFRKPKAKPTPPKRSSSLRKSDGNADISEKKEPKISSGQHLP-HSSREMKLPLDFSNTPS Q5RE45_PONAB Q5RE45_PONAB SFRKPKAKPTPPKRSSSLRKSDGNADISEKKESKISSGQHLP-HSSREMKLPLDFANTPS B7Z7S2_HUMAN B7Z7S2_HUMAN SFRKPKAKPTPPKRSSSLRKSDGDADISEKKEPKISSGQHLP-HSSREMKLPLDFANTPS B7ZVX8_HUMAN B7ZVX8_HUMAN SFRKPKAKPTPPKRSSSLRKSDGNADISEKKEPKISSGQHLP-HSSREMKLPLDFANTPS NHS_HUMAN NHS_HUMAN SFRKPKAKPTPPKRSSSLRKSDGNADISEKKEPKISSGQHLP-HSSREMKLPLDFANTPS MATCH **:****:**************.::** ****.** .**: **********:::* ** CONSENSUS SFRKPKAKPTPPKRSSSLRKSDGNADISEKKEPKISSGQHLP?HSSREMKLPLDF?NTPS

Q5U4N4_XENLA Q5U4N4_XENLA RVENFATPNQQEIPWVNQDDNDLKSTQFLTTDVPSFKYESGEQSHYADLWLVNDLKTSDP B7ZWM3_MOUSE B7ZWM3_MOUSE RVENANLPAKLDSSWINQSEHAIKEPQLDTPDISPFKDEGAESTHYADLWLLNDLKTNDP B2RXX7_MOUSE B2RXX7_MOUSE RVENANLPAKLDSSWINQSEHAIKEPQLDTPDISPFKDEGAESTHYADLWLLNDLKTNDP B1AV60_MOUSE B1AV60_MOUSE RVENANLPAKLDSSWINQSEHAIKEPQLDTPDISPFKDEGAESTHYADLWLLNDLKTNDP B9EJX2_MOUSE B9EJX2_MOUSE RVENANLPAKLDSSWINQSEHAIKEPQLDTPDISPFKDEGAESTHYADLWLLNDLKTNDP Q5RE45_PONAB Q5RE45_PONAB RMENANLPTKQEPSWINQSEHGIKEPQLDASDIPPFKDEVAESTHYADLWLLNDLKTNDP B7Z7S2_HUMAN B7Z7S2_HUMAN RMENASLPTKQEPSWINQSEQGIKEPQLDASDIPPFKDEVAESTHYADLWLLNDLKTNDP B7ZVX8_HUMAN B7ZVX8_HUMAN RMENANLPTKQEPSWINQSEQGIKEPQLDASDIPPFKDEVAESTHYADLWLLNDLKTNDP NHS_HUMAN NHS_HUMAN RMENANLPTKQEPSWINQSEQGIKEPQLDASDIPPFKDEVAESTHYADLWLLNDLKTNDP MATCH *:** * : : .*:**.:: :*..*: :.*:..** * .*.:*******:*****.** CONSENSUS R?ENA?LP?K???SWINQSE??IKEPQLD??DI?PFKDE?AESTHYADLWLLNDLKTNDP

Q5U4N4_XENLA Q5U4N4_XENLA YRSLSNSSTATGTTVIECIKSPESSESQMSQSESRATSPSLPSVENEFKLSSPEKLAGLA B7ZWM3_MOUSE B7ZWM3_MOUSE YRSLSNSSTATGTTVIECIKSPESSESQTSQSESRATTPSLPSVDNEYKLASPEKLAGLA B2RXX7_MOUSE B2RXX7_MOUSE YRSLSNSSTATGTTVIECIKSPESSESQTSQSESRATTPSLPSVDNEYKLASPEKLAGLA B1AV60_MOUSE B1AV60_MOUSE YRSLSNSSTATGTTVIECIKSPESSESQTSQSESRATTPSLPSVDNEYKLASPEKLAGLA B9EJX2_MOUSE B9EJX2_MOUSE YRSLSNSSTATGTTVIECIKSPESSESQTSQSESRATTPSLPSVDNEYKLASPEKLAGLA Q5RE45_PONAB Q5RE45_PONAB YRSLSNSSTATGTTVIECIKSPESSESQTSQSESRATTPSLPSVDNEFKLASPEKLAGLA B7Z7S2_HUMAN B7Z7S2_HUMAN YRSLSNSSTDTGTTVIECIKSPESSESQTSQSESRATTPSLPSVDNEFKLASPEKLAGLA B7ZVX8_HUMAN B7ZVX8_HUMAN YRSLSNSSTATGTTVIECIKSPESSESQTSQSESRATTPSLPSVDNEFKLASPEKLAGLA NHS_HUMAN NHS_HUMAN YRSLSNSSTATGTTVIECIKSPESSESQTSQSESRATTPSLPSVDNEFKLASPEKLAGLA MATCH ********* ****************** ********:******:**:**:********* CONSENSUS YRSLSNSSTATGTTVIECIKSPESSESQTSQSESRATTPSLPSVDNE?KLASPEKLAGLA

Q5U4N4_XENLA Q5U4N4_XENLA SPSSGYSSQSETPTSSFPTPFFSGPLSPGGSKRKPKVPERKSSLQHPSAKCCNVLGGKEL B7ZWM3_MOUSE B7ZWM3_MOUSE SPSSGYSSQSETPTSSFPTAFFSGPLSPGGSKRKPKVPERKSSLQQPSLKDGALSLSKDF B2RXX7_MOUSE B2RXX7_MOUSE SPSSGYSSQSETPTSSFPTAFFSGPLSPGGSKRKPKVPERKSSLQQPSLKDGALSLSKDF B1AV60_MOUSE B1AV60_MOUSE SPSSGYSSQSETPTSSFPTAFFSGPLSPGGSKRKPKVPERKSSLQQPSLKDGALSLSKDF B9EJX2_MOUSE B9EJX2_MOUSE SPSSGYSSQSETPTSSFPTAFFSGPLSPGGSKRKPKVPERKSSLQQPSLKDGALSLSKDF Q5RE45_PONAB Q5RE45_PONAB SPSSGYSSQSETPTSSFPTAFFSGPLSPGGSKRKPKVPERKSSLQQPSLKDGTISLGKDL B7Z7S2_HUMAN B7Z7S2_HUMAN SPSSGYSSQSETPTSSFPTAFFSGPLSPGGSKRKPKVPERKSSLQQPSLKDGTISLSKDL B7ZVX8_HUMAN B7ZVX8_HUMAN SPSSGYSSQSETPTSSFPTAFFSGPLSPGGSKRKPKVPERKSSLQQPSLKDGTISLSKDL NHS_HUMAN NHS_HUMAN SPSSGYSSQSETPTSSFPTAFFSGPLSPGGSKRKPKVPERKSSLQQPSLKDGTISLSKDL MATCH *******************.*************************:** * : .*:: CONSENSUS SPSSGYSSQSETPTSSFPTAFFSGPLSPGGSKRKPKVPERKSSLQQPSLKDG??SL?KD?

Q5U4N4_XENLA Q5U4N4_XENLA ELPTIPPTNLDLSALH-VLHKPLPYRPHIHAFSHNNQNMSEDQFDSNSSTALAITPSVLK B7ZWM3_MOUSE B7ZWM3_MOUSE ELPIIPPSHLDLSALH-VLNKPFHHRHPLHVFTH-KQNTVGDMPRSNPAPSLAITPTVLK B2RXX7_MOUSE B2RXX7_MOUSE ELPIIPPSHLDLSALH-VLNKPFHHRHPLHVFTH-KQNTVGDMPRSNPAPSLAITPTVLK B1AV60_MOUSE B1AV60_MOUSE ELPIIPPSHLDLSALH-VLNKPFHHRHPLHVFTH-KQNTVGDMPRSNPAPSLAITPTVLK B9EJX2_MOUSE B9EJX2_MOUSE ELPIIPPSHLDLSALH-VLNKPFHHRHPLHVFTH-KQNTVGDMPRSNPAPSLAITPTVLK Q5RE45_PONAB Q5RE45_PONAB ELPIIPPTHLDLSALHNVLNKPFHHRHPLHVFTHNKQNTVGETLRSNPPPSLAITPTILK B7Z7S2_HUMAN B7Z7S2_HUMAN ELPIIPPTHLDLSALHNVLNKPFHHRHPLHVFTHNKQNTVGETLRSNPPPSLAITPTILK B7ZVX8_HUMAN B7ZVX8_HUMAN ELPIIPPTHLDLSALHNVLNKPFHHRHPLHVFTHNKQNTVGETLRSNPPPSLAITPTILK NHS_HUMAN NHS_HUMAN ELPIIPPTHLDLSALHNVLNKPFHHRHPLHVFTHNKQNTVGETLRSNPPPSLAITPTILK MATCH *** ***::******* **:**: :* :*.*:* :** : **...:*****::** CONSENSUS ELPIIPP?HLDLSALH?VLNKPFHHRHPLHVFTH?KQNTVG???RSNP?PSLAITPT?LK

Q5U4N4_XENLA Q5U4N4_XENLA SVQLRSVNKQHK-KSKQRETCNIVCSQDPTIT---VDTYTTEKTIVTSARKSILRQFSTE B7ZWM3_MOUSE B7ZWM3_MOUSE SVNLRSISKSEEVRQKEGNNTDLPYLEENAATAASVASLSPSKARPHTAKKSISRQYSAE B2RXX7_MOUSE B2RXX7_MOUSE SVNLRSISKSEEVRQKEGNNTDLPYLEENAATAASVASLSPSKARPHTAKKSISRQYSAE B1AV60_MOUSE B1AV60_MOUSE SVNLRSISKSEEVRQKEGNNTDLPYLEENAATAASVASLSPSKARPHTAKKSISRQYSAE B9EJX2_MOUSE B9EJX2_MOUSE SVNLRSISKSEEVRQKEGNNTDLPYLEENAATAASVASLSPSKARPHTAKKSISRQYSAE Q5RE45_PONAB Q5RE45_PONAB SVNLRSINKSEEAKQ--------------------------------------------- B7Z7S2_HUMAN B7Z7S2_HUMAN SVNLRSINKSEEVK---------------------------------------------- B7ZVX8_HUMAN B7ZVX8_HUMAN SVNLRSINKSEEVKQKEENNTDLPYLEESTLT---TAALSPSKIRPHTANKSVSRQYSTE NHS_HUMAN NHS_HUMAN SVNLRSINKSEEVKQKEENNTDLPYLEESTLT---TAALSPSKIRPHTANKSVSRQYSTE MATCH **:***:.*..: : CONSENSUS SVNLRSI?KSEE????????????????????????????????????????????????

Q5U4N4_XENLA Q5U4N4_XENLA EVILPYIDSSPVDTSPQSMFFDKCELFTGHGMYRQDKGTNI------FGVTKEPWT--HE B7ZWM3_MOUSE B7ZWM3_MOUSE DTLLPFLDSSVAEMGPEK-HLEKNPNFDGKSHGDPETATSASSNLPDSNVMKEQIQMESE B2RXX7_MOUSE B2RXX7_MOUSE DTLLPFLDSSVAEMGPEK-HLEKNPNFDGKSHGDPETATSASSNLPDSNVMKEQIQMESE B1AV60_MOUSE B1AV60_MOUSE DTLLPFLDSSVAEMGPEK-HLEKNPNFDGKSHGDPETATSASSNLPDSNVMKEQIQMESE B9EJX2_MOUSE B9EJX2_MOUSE DTLLPFLDSSVAEMGPEK-HLEKNPNFDGKSHGDPETATSASSNLPDSNVMKEQIQMESE Q5RE45_PONAB Q5RE45_PONAB ------------------------------------------------------------ B7Z7S2_HUMAN B7Z7S2_HUMAN ------------------------------------------------------------ B7ZVX8_HUMAN B7ZVX8_HUMAN DTILSFLDSSAVEMGPDKLHLEKNSTFDVKNRCDPETITSAGSSLLDSNVTKDQVRTETE NHS_HUMAN NHS_HUMAN DTILSFLDSSAVEMGPDKLHLEKNSTFDVKNRCDPETITSAGSSLLDSNVTKDQVRTETE MATCH CONSENSUS ????????????????????????????????????????????????????????????

Q5U4N4_XENLA Q5U4N4_XENLA IVQETVFLAQPETTTTTFQEYYEKKNCN-EIAVEQCGHVQEDNQLKLTPDIHIQDDVMTI B7ZWM3_MOUSE B7ZWM3_MOUSE LISENILSKNCGFST-GFQRVSASRPSDLGSKMIQYGASPDGTVQQGQKAPSGVREEGGK B2RXX7_MOUSE B2RXX7_MOUSE LISENILRKNCGFST-GFQRVSASRPSDLGSKMIQYGASPDGTVQQGQKAPSGVREEGGK B1AV60_MOUSE B1AV60_MOUSE LISENILSKNCGFST-GFQRVSASRPSDLGSKMIQYGASPDGTVQQGQKAPSGVREEGGK B9EJX2_MOUSE B9EJX2_MOUSE LISENILSKNCGFST-GFQRVSASRPSDLGSKMIQYGASPDGTVQQGQKAPSGVREEGGK Q5RE45_PONAB Q5RE45_PONAB ------------------------------------------------------------ B7Z7S2_HUMAN B7Z7S2_HUMAN ------------------------------------------------------------ B7ZVX8_HUMAN B7ZVX8_HUMAN PIPENTPTKNCAFPTEGFQRVSAARPNDLDGKIIQYGPGPDETLEQVQKAPSAGLEEVAQ NHS_HUMAN NHS_HUMAN PIPENTPTKNCAFPTEGFQRVSAARPNDLDGKIIQYGPGPDETLEQVQKAPSAGLEEVAQ MATCH CONSENSUS ????????????????????????????????????????????????????????????

Q5U4N4_XENLA Q5U4N4_XENLA PEPIKEITTEFALQDNAAEKFLSHDNEPDLS-NNDKVPGNTLSFESELSTVYSLSDECPE B7ZWM3_MOUSE B7ZWM3_MOUSE PESVDGITLQANSSTRVTDISSQYKHQRVISRHHDKVPV-TIRHESEMSTVNSFPEKCSE B2RXX7_MOUSE B2RXX7_MOUSE PESVDGITLQANSSTRVTDISSQYKHQRVISRHHDKVPV-TIRHESEMSTVNSFPEKCSE B1AV60_MOUSE B1AV60_MOUSE PESVDGITLQANSSTRVTDISSQYKHQRVISRHHDKVPV-TIRHESEMSTVNSFPEKCSE B9EJX2_MOUSE B9EJX2_MOUSE PESVDGITLQANSSTRVTDISSQYKHQRVISRHHDKVPV-TIRHESEMSTVNSFPEKCSE Q5RE45_PONAB Q5RE45_PONAB ------------------------------------------------------------ B7Z7S2_HUMAN B7Z7S2_HUMAN ------------------------------------------------------------ B7ZVX8_HUMAN B7ZVX8_HUMAN PESVDVITSQSDSPTRATDVSNQFKHQFVMSRHHDKVPG-TISYESEITSVNSFPEKCSK NHS_HUMAN NHS_HUMAN PESVDVITSQSDSPTRATDVSNQFKHQFVMSRHHDKVPG-TISYESEITSVNSFPEKCSK MATCH CONSENSUS ????????????????????????????????????????????????????????????

Q5U4N4_XENLA Q5U4N4_XENLA QESEFVSGIPTKSASEDNRSYDPSENMEDTSEKESSQSEDYLISPMSEDSQADTDDVFVS B7ZWM3_MOUSE B7ZWM3_MOUSE QEN-IASGISPQSASDNSRAEETQGSMDETSLKESSPSDDSITSPLSEDSQAGAEGVFVS B2RXX7_MOUSE B2RXX7_MOUSE QEN-IASGISPQSASDNSRAEETQGSMDETSLKESSPSDDSITSPLSEDSQAGAEGVFVS B1AV60_MOUSE B1AV60_MOUSE QEN-IASGISPQSASDNSRAEETQGSMDETSLKESSPSDDSITSPLSEDSQAGAEGVFVS B9EJX2_MOUSE B9EJX2_MOUSE QEN-IASGISPQSASDNSRAEETQGSMDETSLKESSPSDDSITSPLSEDSQAGAEGVFVS Q5RE45_PONAB Q5RE45_PONAB ------------------------------------------------------------ B7Z7S2_HUMAN B7Z7S2_HUMAN ------------------------------------------------------------ B7ZVX8_HUMAN B7ZVX8_HUMAN QEN-IASGISAKSASDNSKAEETQGNVDEASLKESSPSDDSIISPLSEDSQAEAEGVFVS NHS_HUMAN NHS_HUMAN QEN-IASGISAKSASDNSKAEETQGNVDEASLKESSPSDDSIISPLSEDSQAEAEGVFVS MATCH CONSENSUS ????????????????????????????????????????????????????????????

Q5U4N4_XENLA Q5U4N4_XENLA PNKPRTTDDLFAAIHRSKRKVLGRKDSGDSTVKNKSRPLTGSSGASA------------- B7ZWM3_MOUSE B7ZWM3_MOUSE PNKPRTTEDLFAVIHRSKRKVLGRKDSGDMSVRSKSRVPLGSSSSSANSVTSPSSNVTAG B2RXX7_MOUSE B2RXX7_MOUSE PNKPRTTEDLFAVIHRSKRKVLGRKDSGDMSVRSKSRVPLGSSSSSANSVTSPSSNVTAG B1AV60_MOUSE B1AV60_MOUSE PNKPRTTEDLFAVIHRSKRKVLGRKDSGDMSVRSKSRVPLGSSSSSANSVTSPSSNVTAG B9EJX2_MOUSE B9EJX2_MOUSE PNKPRTTEDLFAVIHRSKRKVLGRKDSGDMSVRSKSRVPLGSSSSSANSVTSPSSNVTAG Q5RE45_PONAB Q5RE45_PONAB ------------------------------------------------------------ B7Z7S2_HUMAN B7Z7S2_HUMAN ------------------------------------------------------------ B7ZVX8_HUMAN B7ZVX8_HUMAN PNKPRTTEDLFAVIHRSKRKVLGRKDSGDMSVRSKSRAPLSSSSSSASSITSPSSNVTTP NHS_HUMAN NHS_HUMAN PNKPRTTEDLFAVIHRSKRKVLGRKDSGDMSVRSKSRAPLSSSSSSASSITSPSSNVTTP MATCH CONSENSUS ????????????????????????????????????????????????????????????

Q5U4N4_XENLA Q5U4N4_XENLA ASQRSPGLIYRSAKKSNTSNEEFKLLLLKKGSRSETSYRMSATEILKSPVTPKSLVDLAL B7ZWM3_MOUSE B7ZWM3_MOUSE TSQRSPGLIYRNAKKSNTSNEEFKLLLLKKGSRSDSSYRMSATEILKSPVLPKPPGEFTA B2RXX7_MOUSE B2RXX7_MOUSE TSQRSPGLIYRNAKKSNTSNEEFKLLLLKKGSRSDSSYRMSATEILKSPVLPKPPGEFTA B1AV60_MOUSE B1AV60_MOUSE TSQRSPGLIYRNAKKSNTSNEEFKLLLLKKGSRSDSSYRMSATEILKSPVLPKPPGEFTA B9EJX2_MOUSE B9EJX2_MOUSE TSQRSPGLIYRNAKKSNTSNEEFKLLLLKKGSRSDSSYRMSATEILKSPVLPKPPGEFTA Q5RE45_PONAB Q5RE45_PONAB ------------------------------------------------------------ B7Z7S2_HUMAN B7Z7S2_HUMAN ------------------------------------------------------------ B7ZVX8_HUMAN B7ZVX8_HUMAN NSQRSPGLIYRNAKKSNTSNEEFKLLLLKKGSRSDSSYRMSATEILKSPILPKPPGELTA NHS_HUMAN NHS_HUMAN NSQRSPGLIYRNAKKSNTSNEEFKLLLLKKGSRSDSSYRMSATEILKSPILPKPPGELTA MATCH CONSENSUS ????????????????????????????????????????????????????????????

Q5U4N4_XENLA Q5U4N4_XENLA DSSSSSEDGSQLSPGSDAFSPISPCSPRVISEGFSAKSGTMSAASRVGRSRVPPAASSSR B7ZWM3_MOUSE B7ZWM3_MOUSE ESPQSPDDTHQGTPGTEALSPLSPCSPRVNAEGFSSKNFATSASARVGRSRVPPVASSSR B2RXX7_MOUSE B2RXX7_MOUSE ESPQSPDDTHQGTPGTEALSPLSPCSPRVNAEGFSSKNFATSASARVGRSRVPPVASSSR B1AV60_MOUSE B1AV60_MOUSE ESPQSPDDTHQGTPGTEALSPLSPCSPRVNAEGFSSKNFATSASARVGRSRVPPVASSSR B9EJX2_MOUSE B9EJX2_MOUSE ESPQSPDDTHQGTPGTEALSPLSPCSPRVNAEGFSSKNFATSASARVGRSRVPPVASSSR Q5RE45_PONAB Q5RE45_PONAB ------------------------------------------------------------ B7Z7S2_HUMAN B7Z7S2_HUMAN ------------------------------------------------------------ B7ZVX8_HUMAN B7ZVX8_HUMAN ESPQSTDDAHQGSQGAEALSPLSPCSPRVNAEGFSSKSFATSASARVGRSRAPPAASSSR NHS_HUMAN NHS_HUMAN ESPQSTDDAHQGSQGAEALSPLSPCSPRVNAEGFSSKSFATSASARVGRSRAPPAASSSR MATCH CONSENSUS ????????????????????????????????????????????????????????????

Q5U4N4_XENLA Q5U4N4_XENLA YSVRCRFYNAPMQAISEGETENSDGSPHDDRSSQSSM B7ZWM3_MOUSE B7ZWM3_MOUSE YSVRCRLYNTPMQAISEGETENSDGSPHDDRSSQSST B2RXX7_MOUSE B2RXX7_MOUSE YSVRCRLYNTPMQAISEGETENSDGSPHDDRSSQSST B1AV60_MOUSE B1AV60_MOUSE YSVRCRLYNTPMQAISEGETENSDGSPHDDRSSQSST B9EJX2_MOUSE B9EJX2_MOUSE YSVRCRLYNTPMQAISEGETENSDGSPHDDRSSQSST Q5RE45_PONAB Q5RE45_PONAB ------------------------------------- B7Z7S2_HUMAN B7Z7S2_HUMAN ------------------------------------- B7ZVX8_HUMAN B7ZVX8_HUMAN YSVRCRLYNTPMQAISEGETENSDGSPHDDRSSQSST NHS_HUMAN NHS_HUMAN YSVRCRLYNTPMQAISEGETENSDGSPHDDRSSQSST MATCH CONSENSUS ?????????????????????????????????????


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