Alignment of the gene Family HBG052970 of HOVERGEN

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Threshold: 50% 80% 100%
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Isoforms are ON
GTPB6_XENLA GTPB6_XENLA ---MLLVRASRAVRCCCSYSLHKTVTFQARHSLYSAH----------------------- Q8K372_MOUSE Q8K372_MOUSE ------------------------------------------------------------ GTPB6_MOUSE GTPB6_MOUSE LFLRAAVLPGFWLPRVRRVQLVRSPAVTLPSPVRTVH----------------------- Q8VDE1_MOUSE Q8VDE1_MOUSE ------------------------------------------------------------ A8MVW8_HUMAN A8MVW8_HUMAN ------------------------------------------------------------ GTPB6_HUMAN GTPB6_HUMAN ------------------------------------------------------------ Q4SD89_TETNG Q4SD89_TETNG AAPRALRRCLPLLRRSCPRFGPPTRAFLRARPVAA------------------------- B5X2D9_SALSA B5X2D9_SALSA STIRYCMLGNNIVTRLFPKRTYSWCVQLKHQQLYSAENWLKLPTCYNCHKRSHHVNQSSH Q0D283_DANRE Q0D283_DANRE ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

GTPB6_XENLA GTPB6_XENLA --------------KVHSNGHFHLPLSGIRCFFSGSPYWKAKKHGGEHSKAGNLTAIDDY Q8K372_MOUSE Q8K372_MOUSE ------------------------------------------------------------ GTPB6_MOUSE GTPB6_MOUSE ---------------------------------AGSRVWGSAWAGGGPVRGGGEEDPRE- Q8VDE1_MOUSE Q8VDE1_MOUSE ------------------------------------------------------------ A8MVW8_HUMAN A8MVW8_HUMAN ------------------------------------------------------------ GTPB6_HUMAN GTPB6_HUMAN ------------------------------------------------------------ Q4SD89_TETNG Q4SD89_TETNG ---------------------------------SAGRRTSTDHTAGNGRYPVPSEEEEED B5X2D9_SALSA B5X2D9_SALSA QHISQYGLQHHRDTTLSWQTSIPLQHRGFSLSTYQQKIRDDNHTPGHESLGKEEEDYID- Q0D283_DANRE Q0D283_DANRE ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

GTPB6_XENLA GTPB6_XENLA WLEEVEEELEDLDLSPHTASLLQGAHRVFIVHPDVKWGAKKDQLSTADLQVAEAAALVHS Q8K372_MOUSE Q8K372_MOUSE ------------------------------------------------------------ GTPB6_MOUSE GTPB6_MOUSE -----DEEEEEDELLRAPPLLPLDTQRVCVLHPDVKRPAGKKPRSTAEWQVAEAAALVRA Q8VDE1_MOUSE Q8VDE1_MOUSE --------------------------------------------------------LVRA A8MVW8_HUMAN A8MVW8_HUMAN ------------------------------------------------------------ GTPB6_HUMAN GTPB6_HUMAN -------------------------------------------MTRAEWQVAEATALVHT Q4SD89_TETNG Q4SD89_TETNG EEFVGDSEVEELFQQRGAAGVGQGQQRLVIVHPDVKWGSRKQHLTTAELMLAEAVGLVNT B5X2D9_SALSA B5X2D9_SALSA -----DSEIDELFQHQ-IPMVGEGDHRIFIVHPDVKWGSRKQYLTTANLMMEEAVGLVNT Q0D283_DANRE Q0D283_DANRE ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

GTPB6_XENLA GTPB6_XENLA LPNWSVVNTLIMSTKSPDSKLIFGKGNFQTLTDVIKGHPQITAVFLNVERLSSLTEKEME Q8K372_MOUSE Q8K372_MOUSE ------------------------------------------------------------ GTPB6_MOUSE GTPB6_MOUSE LPGWSVASTLVVPSAAPGSRLVFGKGNFQDVTEKIKGCQDITSVFLNVERMAPPTKKELE Q8VDE1_MOUSE Q8VDE1_MOUSE LPGWSVASTLVVPSAAPGSRLVFGKGNFQDVTEKIKGCQDITSVFLNVERMAPPTKKELE A8MVW8_HUMAN A8MVW8_HUMAN ------------------------------------------------------------ GTPB6_HUMAN GTPB6_HUMAN LDGWSVVQTMVVSTKTPDRKLIFGKGNFEHLTEKIRGSPDVTCVFLNVERMAAPTKKELE Q4SD89_TETNG Q4SD89_TETNG LDNWTVVDTVVLSTKTPEKKRIFGKGNFQSLTEKIRQTAGITAVFVNVEHLSPLSERELE B5X2D9_SALSA B5X2D9_SALSA LQNWSVIDKVILSTKTPEKKMIFGKGNFQTLTERIRRTPGITAVFVNVERLSPASEKEFE Q0D283_DANRE Q0D283_DANRE ---------------------------FQMLTEKIRATHGVTAVFVNVERLSPSSEKDLE MATCH CONSENSUS ????????????????????????????????????????????????????????????

GTPB6_XENLA GTPB6_XENLA EAWGVKVFDRYTVVLNIFRFNAHTKEAKLQIALAELPLLRSSLKNETAHMDQQGGGSRYI Q8K372_MOUSE Q8K372_MOUSE ----------------------------MQLALAEIPLLRSSVNTDSGQQDQQGWGSRYI GTPB6_MOUSE GTPB6_MOUSE SAWGLRVFDRFTLVLHIFRCNARTREARMQLALAEIPLLRSSVNTDSGQQDQQGWGSRYI Q8VDE1_MOUSE Q8VDE1_MOUSE SAWGLRVFDRFTLVLHIFRCNARTREARMQLALAEIPLLRSSVNTDSGQQDQQGWGSRYI A8MVW8_HUMAN A8MVW8_HUMAN ---------------------------------------XSNLKRDVAHL-YRGVGSRYI GTPB6_HUMAN GTPB6_HUMAN AAWGVEVFDRFTVVLHIFRCNARTKEARLQVALAEMPLHRSNLKRDVAHL-YRGVGSRYI Q4SD89_TETNG Q4SD89_TETNG EAWGVKVLDRYSVVLHIFRCNARTKEAKLQISLAEIPLLRSRLKNEIANLDQQGGRSKYI B5X2D9_SALSA B5X2D9_SALSA EAWGVKVFDRYSVVLHIFRCNARTKEAKLQVSLAEIPLLRSRLRNEVANLDQQGGGSRYI Q0D283_DANRE Q0D283_DANRE EAWGVKVLDRYSLVLHIFRCNAKTKEAKLQISLAEIPLFRSRLRNEVANLDQQGGGSRYI MATCH * :. : .: :* *:** CONSENSUS ?????????????????????????????Q??LAE?PL?RS????????????G?GSRYI

GTPB6_XENLA GTPB6_XENLA MGSGETFLEVQQRLLKEREIKIKYALEKVKKKRNLLRTQRRRREFPIISILGYTNSGKTT Q8K372_MOUSE Q8K372_MOUSE MGSGESPTELRARALRDRELRLRRVLERLRDKRRLMRKERVRREFPVVSVVGYTNCGKTT GTPB6_MOUSE GTPB6_MOUSE MGSGESPTELRARALRDRELRLRRVLERLRDKRRLMRKERVRREFPVVSVVGYTNCGKTT Q8VDE1_MOUSE Q8VDE1_MOUSE MGSGESPTELRARALRDRELRLRRVLERLRDKRRLMRKERVRREFPVVSVVGYTNCGKTT A8MVW8_HUMAN A8MVW8_HUMAN MGSGESFMQLQQRLLREKEAKIRKALDRLRKKRHLLRRQRTRREFPVISVVGYTNCGKTT GTPB6_HUMAN GTPB6_HUMAN MGSGESFMQLQQRLLREKEAKIRKALDRLRKKRHLLRRQRTRREFPVISVVGYTNCGKTT Q4SD89_TETNG Q4SD89_TETNG GGSGETLLEVQQRLLKEREMKIRTALEKLRRKRHLLRAQRKQQEFPMVSVLGYTNSGKTT B5X2D9_SALSA B5X2D9_SALSA MGSGETLMEVQQRVLQERKLKICSALEHLRRKRHLLRSQRKHRDFPIISVMGYTNCGKTT Q0D283_DANRE Q0D283_DANRE MGSGETLYEMQQRLLKERELKIRSALKRLRRKRNLLRSQRKHKDFPIISVMGYTNCGKTT MATCH ****: ::: * *:::: :: .*.::: **.*:* :* :::**::*::****.**** CONSENSUS MGSGE???????R?L???E??????L??LR?KR?L?R??R????FP??SV?GYTN?GKTT

GTPB6_XENLA GTPB6_XENLA LIKALTGDEGLQPRDQLFATLDVTSHAGLLPCHMPVIYVDTIGFLSQLPHNLIESFSATL Q8K372_MOUSE Q8K372_MOUSE LIQALTGEAALQPRDQPFATLDVTVHAGLLPSRLRILYVDTIGFLSQLPHSLIHAFSATL GTPB6_MOUSE GTPB6_MOUSE LIQALTGEAALQPRDQPFATLDVTVHAGLLPSRLRILYVDTIGFLSQLPHNLIHAFSATL Q8VDE1_MOUSE Q8VDE1_MOUSE LIQALTGEAALQPRDQPFATLDVTVHAGLLPSRLRILYVDTIGFLSQLPHSLIHAFSATL A8MVW8_HUMAN A8MVW8_HUMAN LIKALTGDAAIQPRDQLFATLDVTAHAGTLPSRMTVLYVDTIGFLSQLPHGLIESFSATL GTPB6_HUMAN GTPB6_HUMAN LIKALTGDAAIQPRDQLFATLDVTAHAGTLPSRMTVLYVDTIGFLSQLPHGLIESFSATL Q4SD89_TETNG Q4SD89_TETNG LIKSLTGDSGLQPKNQLFATLDVTVHAGQLPNHMTVLYVDTIGFLSQLPHRLIDSFSATL B5X2D9_SALSA B5X2D9_SALSA LIKALTGDAALQPRDQLFATLDVTVHAGTLPSHMSVLYVDTIGFLSQLPHQLIDSFSATL Q0D283_DANRE Q0D283_DANRE LIKALTGDDGLQPKDQLFATLDVTVHAGQLPCHMTVLYVDTIGFLSQLPHQLIDSFSATL MATCH **::***: .:**::* ******* *** ** :: ::************* **.:***** CONSENSUS LI?ALTG????QP?DQ?FATLDVT?HAG?LP?????LYVDTIGFLSQLPH?LI??FSATL

GTPB6_XENLA GTPB6_XENLA EDVVHSDLLIHVRDISHPETTKQKASVLSVLKNLGLPQQLLDTMIEVQNKIDLIDMPENT Q8K372_MOUSE Q8K372_MOUSE EDVAYSDVLVHVTDVSHPDAELQKATVLSTLRGLHLPPALLESALEVHSKVDLVPGYTPP GTPB6_MOUSE GTPB6_MOUSE EDVAYSDVLVHVTDVSHPDAELQKATVLSTLRGLHLPPALLESALEVHSKVDLVPGYTPP Q8VDE1_MOUSE Q8VDE1_MOUSE EDVAYSDVLVHVTDVSHPDAELQKATVLSTLRGLHLPPALLESALEVHSKVDLVPGYTPP A8MVW8_HUMAN A8MVW8_HUMAN EDVAHSDLILHVRDVSHPEAELQKCSVLSTLRGLQLPAPLLDSMVEVHNKVDLVPGYSPT GTPB6_HUMAN GTPB6_HUMAN EDVAHSDLILHVRDVSHPEAELQKCSVLSTLRGLQLPAPLLDSMVEVHNKVDLVPGYSPT Q4SD89_TETNG Q4SD89_TETNG EDIKHSDLLLHVRDVSHPETLNQKANVLNVLKNLQIPDRLIGSMIEVHNKIDLVDSYQFT B5X2D9_SALSA B5X2D9_SALSA EDVTHSDLIVHVRDISHPETVNQKENVLNVLRNLQIPDRLLSSIVEVHNKIDLVDSYEPS Q0D283_DANRE Q0D283_DANRE EDVIHSDLIIHVRDISHPETVSQKVNVLNVLNNLQIPERLLTSIIEVHNKIDLIEGYESS MATCH **: :**:::** *:***:: ** .**..*..* :* *: : :**:.*:**: . CONSENSUS EDV??SD???HV?D?SHP????QK??VL??L??L??P??LL?S??EVH?K?DL???Y???

GTPB6_XENLA GTPB6_XENLA EDSVLSVSALHGHGLEDLKQQVETAVMKSTGRNVVTIKVNLESPQLSWLYKEASVQEVKV Q8K372_MOUSE Q8K372_MOUSE CSGALAVSAISGRGLDELKAALEASVLRATGRQVLTLCVRLGGPQLGWLYKEAVVQQVQE GTPB6_MOUSE GTPB6_MOUSE CSGALAVSAISGRGLDELKAALEASVLRATGRQVLTLCVRLGGPQLGWLYKEAVVQQVQE Q8VDE1_MOUSE Q8VDE1_MOUSE CSGALAVSAISGRGLDELKAALEASVLRATGRQVLTLCVRLGGPQLGWLYKEAVVQQVQE A8MVW8_HUMAN A8MVW8_HUMAN EPNVVPVSALRGHGLQELKAELDAAVLKATGRQILTLRVRLAGAQLSWLYKEATVQEVDV GTPB6_HUMAN GTPB6_HUMAN EPNVVPVSALRGHGLQELKAELDAAVLKATGRQILTLRVRLAGAQLSWLYKEATVQEVDV Q4SD89_TETNG Q4SD89_TETNG DPRALPVSALGGRGLDRLKEAVEAEIVAATGKHTLALPVDLSSPQLSWLYKEAAVQDLEV B5X2D9_SALSA B5X2D9_SALSA EPNNLPISALRGQGLEELKIVVEEAIVRSTGKQVLTLPVDLSSSQLSWLYKEATVQEVDV Q0D283_DANRE Q0D283_DANRE DPEVIPISALKQRGLEALKEKIEEAVLKCTGKQMMTLKVQLNTSQLSWLYKEATVQAVDD MATCH :.:**: :**: ** :: :: .**:: ::: * * .**.****** ** :. CONSENSUS ???????SA??G?GL??LK??????????TG????TL?V?L???QL?WLYKEA?VQ?V??

GTPB6_XENLA GTPB6_XENLA LPEDGTARVRVIITNSAYGKYRKLFCK------------ Q8K372_MOUSE Q8K372_MOUSE LPEGDAAHVTVVITQAAYGRFRKLFPIDAPSALPH---- GTPB6_MOUSE GTPB6_MOUSE LPEGDAAHVTVVITQAAYGRFRKLFPIDAPSALPH---- Q8VDE1_MOUSE Q8VDE1_MOUSE LPEGDAAHVTVVITQAAYGRFRKLFPIDAPSALPH---- A8MVW8_HUMAN A8MVW8_HUMAN IPEDGAADVRVIISNSAYGKFRKLFPG------------ GTPB6_HUMAN GTPB6_HUMAN IPEDGAADVRVIISNSAYGKFRKLFPG------------ Q4SD89_TETNG Q4SD89_TETNG NADDGSAVVKVVISAAAYGRYKKLFSG------------ B5X2D9_SALSA B5X2D9_SALSA NPDEGSAVVKVIISAAAYGRYRKMFQLGVVS-------- Q0D283_DANRE Q0D283_DANRE VGDDCTANVKVIISQAAYGRYRKLFQGTAWSEKCSSVHR MATCH : :* * *:*: :***:::*:* CONSENSUS ??????A?V?V?I???AYG??RKLF??????????????


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