Alignment of the gene Family HBG053554 of HOVERGEN

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Isoforms are ON
Q4SR18_TETNG Q4SR18_TETNG ------------------------------------------------------------ Q6DE42_XENLA Q6DE42_XENLA GFELDRFNGEVDPDFKCNL-CNRVLEDPLTTPCGHVFCAGCVLPWVVQQGSCPVKCQ-RI B7Z5X9_HUMAN B7Z5X9_HUMAN ------------------------------------------------------------ B7ZAG0_HUMAN B7ZAG0_HUMAN ------------------------------------------------------------ B2RWP2_HUMAN B2RWP2_HUMAN GFELDRFDGDVDPDLKCAL-CHKVLEDPLTTPCGHVFCAGCVLPWVVQEGSCPARCRGRL PZRN3_HUMAN PZRN3_HUMAN GFELDRFDGDVDPDLKCAL-CHKVLEDPLTTPCGHVFCAGCVLPWVVQEGSCPARCRGRL B7ZAC9_HUMAN B7ZAC9_HUMAN ------------------------------------------------------------ B7Z2I8_HUMAN B7Z2I8_HUMAN ------------------------------------------------------------ B7Z5Q3_HUMAN B7Z5Q3_HUMAN ------------------------------------------------------------ PZRN3_RAT PZRN3_RAT GFELDRFDGEVDPDLKCAL-CHKVLEDPLTTPCGHVFCAGCVLPWVVQEGSCPSRCRGRL PZRN3_MOUSE PZRN3_MOUSE GFELDRFDGDVDPDLKCAL-CHKVLEDPLTTPCGHVFCAGCVLPWVVQEGSCPARCRGRL Q3UPS8_MOUSE Q3UPS8_MOUSE ------------------------------------------------------------ Q4RSH1_TETNG Q4RSH1_TETNG ------------------------------------------------------------ Q3UXJ7_MOUSE Q3UXJ7_MOUSE ------------------------------------------------------------ B9EKP7_MOUSE B9EKP7_MOUSE GFALERLAEAVDPAFQCQLLCGQVLEEPACTPCGHVFCASCLLPWAAGRRWCPLQCQ-PL Q69Z24_MOUSE Q69Z24_MOUSE ------------------------------------------------------------ B4DGD1_HUMAN B4DGD1_HUMAN ------------------------------------------------------------ PZRN4_HUMAN PZRN4_HUMAN GFALERFAEAVDPALECKL-CGQVLEEPLCTPCGHVFCASCLLPWAVRRRRCPLQCQ-PL B4DG65_HUMAN B4DG65_HUMAN ------------------------------------------------------------ Q4RHM6_TETNG Q4RHM6_TETNG ------------------------------------------------------------ Q5TYS9_DANRE Q5TYS9_DANRE ------------------------------------------------------------ Q5BLD5_DANRE Q5BLD5_DANRE ------------------------------------------------------------ Q4T8B3_TETNG Q4T8B3_TETNG ------------------------------------------------------------ B4F6T6_XENTR B4F6T6_XENTR ------------------------------------------------------------ A2AFG3_MOUSE A2AFG3_MOUSE ------------------------------------------------------------ PDZD4_MOUSE PDZD4_MOUSE ------------------------------------------------------------ B7NZP0_RABIT B7NZP0_RABIT ------------------------------------------------------------ B1MTU2_CALMO B1MTU2_CALMO ------------------------------------------------------------ B3KW03_HUMAN B3KW03_HUMAN ------------------------------------------------------------ B3KVR9_HUMAN B3KVR9_HUMAN ------------------------------------------------------------ B7ZKY3_HUMAN B7ZKY3_HUMAN ------------------------------------------------------------ Q17RL8_HUMAN Q17RL8_HUMAN ------------------------------------------------------------ PDZD4_HUMAN PDZD4_HUMAN ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

Q4SR18_TETNG Q4SR18_TETNG ------------------------------------------------------------ Q6DE42_XENLA Q6DE42_XENLA SAKELNHVLPLKSLILKLDIKCDNYSRGCDKVVKLHSLAEHAEMCDFSPAKCRNKGCSEV B7Z5X9_HUMAN B7Z5X9_HUMAN ------------------------------------------------------------ B7ZAG0_HUMAN B7ZAG0_HUMAN ------------------------------------------------------------ B2RWP2_HUMAN B2RWP2_HUMAN SAKELNHVLPLKRLILKLDIKCAYATRGCGRVVKLQQLPEHLERCDFAPARCRHAGCGQV PZRN3_HUMAN PZRN3_HUMAN SAKELNHVLPLKRLILKLDIKCAYATRGCGRVVKLQQLPEHLERCDFAPARCRHAGCGQV B7ZAC9_HUMAN B7ZAC9_HUMAN ------------------------------------------------------------ B7Z2I8_HUMAN B7Z2I8_HUMAN ------------------------------------------------------------ B7Z5Q3_HUMAN B7Z5Q3_HUMAN ------------------------------------------------------------ PZRN3_RAT PZRN3_RAT SAKELNHVLPLKRLILKLDIKCAHAARGCGRVVKLQDLPEHLERCDFAPARCRHAGCGQL PZRN3_MOUSE PZRN3_MOUSE SAKELNHVLPLKRLILKLDIKCAHAARGCGRVVKLQDLPEHLERCDFAPARCRHAGCGQL Q3UPS8_MOUSE Q3UPS8_MOUSE ------------------------------------------------------------ Q4RSH1_TETNG Q4RSH1_TETNG ------------------------------------------------------------ Q3UXJ7_MOUSE Q3UXJ7_MOUSE ------------------------------------------------------------ B9EKP7_MOUSE B9EKP7_MOUSE APGELYRVLPLRSLVQQLRVQCNYSGQGCGHRG--------------------------- Q69Z24_MOUSE Q69Z24_MOUSE ------------------------------------------------------------ B4DGD1_HUMAN B4DGD1_HUMAN ------------------------------------------------------------ PZRN4_HUMAN PZRN4_HUMAN APGELYRVLPLRSLIQKLRVQCDYRARGCGHSVRLHELEAHVEHCDFGPARR-------- B4DG65_HUMAN B4DG65_HUMAN ------------------------------------------------------------ Q4RHM6_TETNG Q4RHM6_TETNG ------------------------------------------------------------ Q5TYS9_DANRE Q5TYS9_DANRE ------------------------------------------------------------ Q5BLD5_DANRE Q5BLD5_DANRE ------------------------------------------------------------ Q4T8B3_TETNG Q4T8B3_TETNG ------------------------------------------------------------ B4F6T6_XENTR B4F6T6_XENTR ------------------------------------------------------------ A2AFG3_MOUSE A2AFG3_MOUSE ------------------------------------------------------------ PDZD4_MOUSE PDZD4_MOUSE ------------------------------------------------------------ B7NZP0_RABIT B7NZP0_RABIT ------------------------------------------------------------ B1MTU2_CALMO B1MTU2_CALMO ------------------------------------------------------------ B3KW03_HUMAN B3KW03_HUMAN ------------------------------------------------------------ B3KVR9_HUMAN B3KVR9_HUMAN ------------------------------------------------------------ B7ZKY3_HUMAN B7ZKY3_HUMAN ------------------------------------------------------------ Q17RL8_HUMAN Q17RL8_HUMAN ------------------------------------------------------------ PDZD4_HUMAN PDZD4_HUMAN ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

Q4SR18_TETNG Q4SR18_TETNG ------------------------------------------------------------ Q6DE42_XENLA Q6DE42_XENLA LNLRDMDAHMREHCDYRAAGICQKGCGLMITHREHRLGEHCCLKALKGLNSVLQSKISGL B7Z5X9_HUMAN B7Z5X9_HUMAN ------------------------------------------------------------ B7ZAG0_HUMAN B7ZAG0_HUMAN ------------------------------------------------------------ B2RWP2_HUMAN B2RWP2_HUMAN LLRRDVEAHMRDACDARPVGRCQEGCGLPLTHGEQRAGGHCCARALRAHNGALQARLGAL PZRN3_HUMAN PZRN3_HUMAN LLRRDVEAHMRDACDARPVGRCQEGCGLPLTHGEQRAGGHCCARALRAHNGALQARLGAL B7ZAC9_HUMAN B7ZAC9_HUMAN ------------------------------------------------------------ B7Z2I8_HUMAN B7Z2I8_HUMAN ------------------------------------------------------------ B7Z5Q3_HUMAN B7Z5Q3_HUMAN ------------------------------------------------------------ PZRN3_RAT PZRN3_RAT LLRRDVEAHMRDACDARPVGRCQEGCGLPLTHGEQRAGGHCCARALRAHNGALQARLGAL PZRN3_MOUSE PZRN3_MOUSE LLRRDVEAHMRDACDARPVGRCQEGCGLPLTHGEQRAGGHCCARALRAHNGALQARLGAL Q3UPS8_MOUSE Q3UPS8_MOUSE ---------------------------------------DCCARALRAHNGALQARLGAL Q4RSH1_TETNG Q4RSH1_TETNG ------------------------------------------------------------ Q3UXJ7_MOUSE Q3UXJ7_MOUSE ------------------------------------------------------------ B9EKP7_MOUSE B9EKP7_MOUSE ---------------DCGCWQCTSSAAPSALPAAVTATAQAAAEAAGRKSTRRPRPAGVG Q69Z24_MOUSE Q69Z24_MOUSE ------------------------------------------------------------ B4DGD1_HUMAN B4DGD1_HUMAN ------------------------------------------------------------ PZRN4_HUMAN PZRN4_HUMAN ---------------LRSRGGCASGLGGGEVPARGGCGPTPRAGRGGGARGGPPGGRWGR B4DG65_HUMAN B4DG65_HUMAN ------------------------------------------------------------ Q4RHM6_TETNG Q4RHM6_TETNG ------------------------------------------------------------ Q5TYS9_DANRE Q5TYS9_DANRE ------------------------------------------------------------ Q5BLD5_DANRE Q5BLD5_DANRE ------------------------------------------------------------ Q4T8B3_TETNG Q4T8B3_TETNG ------------------------------------------------------------ B4F6T6_XENTR B4F6T6_XENTR ------------------------------------------------------------ A2AFG3_MOUSE A2AFG3_MOUSE ------------------------------------------------------------ PDZD4_MOUSE PDZD4_MOUSE ------------------------------------------------------------ B7NZP0_RABIT B7NZP0_RABIT ------------------------------------------------------------ B1MTU2_CALMO B1MTU2_CALMO ------------------------------------------------------------ B3KW03_HUMAN B3KW03_HUMAN ------------------------------------------------------------ B3KVR9_HUMAN B3KVR9_HUMAN ------------------------------------------------------------ B7ZKY3_HUMAN B7ZKY3_HUMAN ------------------------------------------------------------ Q17RL8_HUMAN Q17RL8_HUMAN ------------------------------------------------------------ PDZD4_HUMAN PDZD4_HUMAN ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

Q4SR18_TETNG Q4SR18_TETNG ------------------------------------------------------------ Q6DE42_XENLA Q6DE42_XENLA ETELKKRALRSGKREKSLLSQLSAVQNELQMTALRYQKKFTEYSTRLDSLTKAVAS---- B7Z5X9_HUMAN B7Z5X9_HUMAN ------------------------------------------------------------ B7ZAG0_HUMAN B7ZAG0_HUMAN ------------------------------------------------------------ B2RWP2_HUMAN B2RWP2_HUMAN HKALKKEALRAGKREKSLVAQLAAAQLELQMTALRYQKKFTEYSARLDSLSRCVAAPPGG PZRN3_HUMAN PZRN3_HUMAN HKALKKEALRAGKREKSLVAQLAAAQLELQMTALRYQKKFTEYSARLDSLSRCVAAPPGG B7ZAC9_HUMAN B7ZAC9_HUMAN ------------------------------------------------------------ B7Z2I8_HUMAN B7Z2I8_HUMAN ------------------------------------------------------------ B7Z5Q3_HUMAN B7Z5Q3_HUMAN ------------------------------------------------------------ PZRN3_RAT PZRN3_RAT HKALKKEALRAGKREKSLLAQLAAAQLELQMTALRYQKKFTEYSARLDSLSRCVAAPPGG PZRN3_MOUSE PZRN3_MOUSE HKALKKEALRAGKREKSLLAQLAAAQLELQMTALRYQKKFTEYSARLDSLSRCVAAPPGG Q3UPS8_MOUSE Q3UPS8_MOUSE HKALKKEALRAGKREKSLVAQLAAAQLELQMTALRYQKKFTEYSARLDSLSRCVAAPPGG Q4RSH1_TETNG Q4RSH1_TETNG ------------------------------------------------------------ Q3UXJ7_MOUSE Q3UXJ7_MOUSE ------------------------------------------------------------ B9EKP7_MOUSE B9EKP7_MOUSE TRVRGHPDLEVGLWLSPAVGVGKTRRAQVSLLQRRYQEKLALYMAHTRNFVGNPGG--RG Q69Z24_MOUSE Q69Z24_MOUSE ------------------------------------------------------------ B4DGD1_HUMAN B4DGD1_HUMAN -------------------------------------------MAHVRNFVGDLGGGHRR PZRN4_HUMAN PZRN4_HUMAN GRGPGPRVLAWRRREKALLAQLWALQGEVQLTARRYQEKFTQYMAHVRNFVGDLGGGHRR B4DG65_HUMAN B4DG65_HUMAN ------------------------------------------------------------ Q4RHM6_TETNG Q4RHM6_TETNG ------------------------------------------------------------ Q5TYS9_DANRE Q5TYS9_DANRE ------------------------------------------------------------ Q5BLD5_DANRE Q5BLD5_DANRE ------------------------------------------------------------ Q4T8B3_TETNG Q4T8B3_TETNG ------------------------------------------------------------ B4F6T6_XENTR B4F6T6_XENTR ------------------------------------------------------------ A2AFG3_MOUSE A2AFG3_MOUSE ------------------------------------------------------------ PDZD4_MOUSE PDZD4_MOUSE ------------------------------------------------------------ B7NZP0_RABIT B7NZP0_RABIT ------------------------------------------------------------ B1MTU2_CALMO B1MTU2_CALMO ------------------------------------------------------------ B3KW03_HUMAN B3KW03_HUMAN ------------------------------------------------------------ B3KVR9_HUMAN B3KVR9_HUMAN ------------------------------------------------------------ B7ZKY3_HUMAN B7ZKY3_HUMAN ------------------------------------------------------------ Q17RL8_HUMAN Q17RL8_HUMAN ------------------------------------------------------------ PDZD4_HUMAN PDZD4_HUMAN ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

Q4SR18_TETNG Q4SR18_TETNG ----------------------------------------------MGCSVCTLQKPPEH Q6DE42_XENLA Q6DE42_XENLA ---------------------------PGKDNQDGPSSEGIYVSKIVDSGPAGKEGGLQI B7Z5X9_HUMAN B7Z5X9_HUMAN ----------------------------------------------MGCSLCSLQKQEEQ B7ZAG0_HUMAN B7ZAG0_HUMAN ----------------------------------------------MGCSLCSLQKQEEQ B2RWP2_HUMAN B2RWP2_HUMAN KGEETKSLTLVLHRDSGSLGFNIIGGRPSVDNHDGSSSEGIFVSKIVDSGPAAKEGGLQI PZRN3_HUMAN PZRN3_HUMAN KGEETKSLTLVLHRDSGSLGFNIIGGRPSVDNHDGSSSEGIFVSKIVDSGPAAKEGGLQI B7ZAC9_HUMAN B7ZAC9_HUMAN ----------------------------------MKMEHKRMILLFSKFTLIHKPHGGRW B7Z2I8_HUMAN B7Z2I8_HUMAN ------------------------------------------------------------ B7Z5Q3_HUMAN B7Z5Q3_HUMAN ----------------------------------MKMEHKRMILLFSKFTLIHKPHGGRW PZRN3_RAT PZRN3_RAT -GEETKSLTLVLHRDSGSLGFNIIGGRPCVDNQDGSSSEGIFVSKIVDSGPAAKEGGLQI PZRN3_MOUSE PZRN3_MOUSE KGEETKSLTLVLHRDSGSLGFNIIGGRPCVDNQDGSSSEGIFVSKIVDSGPAAKEGGLQI Q3UPS8_MOUSE Q3UPS8_MOUSE KGEETKSLTLVLHRDSGSLGFNIIGGRPCVDNQDGSSSEGIFVSKIVDSGPAAKEGGLQI Q4RSH1_TETNG Q4RSH1_TETNG ------------------------------------------------------------ Q3UXJ7_MOUSE Q3UXJ7_MOUSE ----------------------------------------------MGCNLCTFQKREEH B9EKP7_MOUSE B9EKP7_MOUSE QDGEQKPFTVVLEREDDTLGFNIIGGRPYQNSQKQSAPEGIYVSKILENGPADRADGLEV Q69Z24_MOUSE Q69Z24_MOUSE ------------------------------------------------------------ B4DGD1_HUMAN B4DGD1_HUMAN DG-EHKPFTIVLERENDTLGFNIIGGRPNQNNQEGTSTEGIYVSKILENGRADRADGLEI PZRN4_HUMAN PZRN4_HUMAN DG-EHKPFTIVLERENDTLGFNIIGGRPNQNNQEGTSTEGIYVSKILENGPADRADGLEI B4DG65_HUMAN B4DG65_HUMAN ----------------------------------------------MGCNLCTFQKREEH Q4RHM6_TETNG Q4RHM6_TETNG ------------------------------------------------------------ Q5TYS9_DANRE Q5TYS9_DANRE ----------------------------------------------MGCNLCTLQKREEH Q5BLD5_DANRE Q5BLD5_DANRE ------------------------------------------------------------ Q4T8B3_TETNG Q4T8B3_TETNG ------------------------------------------------------------ B4F6T6_XENTR B4F6T6_XENTR ----------------------------------------------MGCNMCVVRKPEEH A2AFG3_MOUSE A2AFG3_MOUSE ----------------------------------------------MGCNMCVVQKPEEQ PDZD4_MOUSE PDZD4_MOUSE ----------------------------------------------MGCNMCVVQKPEEQ B7NZP0_RABIT B7NZP0_RABIT -----------------------------------------------GVSLL-------- B1MTU2_CALMO B1MTU2_CALMO ----------------------------------------------MGCNMCVVQKPEEQ B3KW03_HUMAN B3KW03_HUMAN ------------------------------------------------------------ B3KVR9_HUMAN B3KVR9_HUMAN ------------------------------------------------------------ B7ZKY3_HUMAN B7ZKY3_HUMAN ----------------------------------------------MGCNMCVVQKPEEQ Q17RL8_HUMAN Q17RL8_HUMAN ----------------------------------------------MGCNMCVVQKPEEQ PDZD4_HUMAN PDZD4_HUMAN ----------------------------------------------MGCNMCVVQKPEEQ MATCH CONSENSUS ????????????????????????????????????????????????????????????

Q4SR18_TETNG Q4SR18_TETNG YDLLYQLRGDPPPTEGTEAECAGLNKAEAKGFVSGSPPSSSPRVPGNQVNGKDLSKATHD Q6DE42_XENLA Q6DE42_XENLA HDRII------------------------------------------EVNGKDLSRATHD B7Z5X9_HUMAN B7Z5X9_HUMAN YKLLYEV---------------------------------------CQVNGRDLSRATHD B7ZAG0_HUMAN B7ZAG0_HUMAN YKLLYEV---------------------------------------CQVNGRDLSRATHD B2RWP2_HUMAN B2RWP2_HUMAN HDRII------------------------------------------EVNGRDLSRATHD PZRN3_HUMAN PZRN3_HUMAN HDRII------------------------------------------EVNGRDLSRATHD B7ZAC9_HUMAN B7ZAC9_HUMAN Y----------------------------------------------LVNGRDLSRATHD B7Z2I8_HUMAN B7Z2I8_HUMAN ------------------------------------------------------------ B7Z5Q3_HUMAN B7Z5Q3_HUMAN Y----------------------------------------------LVNGRDLSRATHD PZRN3_RAT PZRN3_RAT HDRII------------------------------------------EVNGKDLSRATHD PZRN3_MOUSE PZRN3_MOUSE HDRII------------------------------------------EVNGKDLSRATHD Q3UPS8_MOUSE Q3UPS8_MOUSE HDRII------------------------------------------EVNGKDLSRATHD Q4RSH1_TETNG Q4RSH1_TETNG ------------------------------------------------VNGKELSKSSHE Q3UXJ7_MOUSE Q3UXJ7_MOUSE YKLLYEVS---------------------------------------QVNGRDLSKATHE B9EKP7_MOUSE B9EKP7_MOUSE HDKII------------------------------------------AVNGRDLSKATHE Q69Z24_MOUSE Q69Z24_MOUSE ------------------------------------------------------------ B4DGD1_HUMAN B4DGD1_HUMAN HDKIM------------------------------------------EVNGKDLSKATHE PZRN4_HUMAN PZRN4_HUMAN HDKIM------------------------------------------EVNGKDLSKATHE B4DG65_HUMAN B4DG65_HUMAN YKLLYEVS---------------------------------------QVNGKDLSKATHE Q4RHM6_TETNG Q4RHM6_TETNG ---FL------------------------------------------QVNAREFAKVDHE Q5TYS9_DANRE Q5TYS9_DANRE YKLLYEIA---------------------------------------QVNGREFSKSGHD Q5BLD5_DANRE Q5BLD5_DANRE ------------------------------------------------------------ Q4T8B3_TETNG Q4T8B3_TETNG ------------------------------------------------------------ B4F6T6_XENTR B4F6T6_XENTR YKVML------------------------------------------QVNGKDLSRLSQE A2AFG3_MOUSE A2AFG3_MOUSE YKVML------------------------------------------------------- PDZD4_MOUSE PDZD4_MOUSE YKVML------------------------------------------QVNGKELSKLSQE B7NZP0_RABIT B7NZP0_RABIT -----------------------------------------------QVNGKELSKLSQE B1MTU2_CALMO B1MTU2_CALMO YKVML------------------------------------------QVNGKELSKLSQE B3KW03_HUMAN B3KW03_HUMAN ------------------------------------------------------------ B3KVR9_HUMAN B3KVR9_HUMAN ------------------------------------------------------------ B7ZKY3_HUMAN B7ZKY3_HUMAN YKVML------------------------------------------------------- Q17RL8_HUMAN Q17RL8_HUMAN YKVML------------------------------------------QVNGKELSKLSQE PDZD4_HUMAN PDZD4_HUMAN YKVML------------------------------------------QVNGKELSKLSQE MATCH CONSENSUS ????????????????????????????????????????????????????????????

Q4SR18_TETNG Q4SR18_TETNG QAV-EAFRTAKEPIVVQVLRRAPPPKP-V-DLAADSQVSDVSTQTDITLQHITALTDLPP Q6DE42_XENLA Q6DE42_XENLA QAV-EAFKTAKEPIVVQVLRRTPRTNV-F-NTPTDVQLMDMGTQTEITFEHIAALAKISS B7Z5X9_HUMAN B7Z5X9_HUMAN QAV-EAFKTAKEPIVVQVLRRTPRTKM-F-TPPSESQLVDTGTQTDITFEHIMALTKMSS B7ZAG0_HUMAN B7ZAG0_HUMAN QAV-EAFKTAKEPIVVQVLRRTPRTKM-F-TPPSESQLVDTGTQTDITFEHIMALTKMSS B2RWP2_HUMAN B2RWP2_HUMAN QAV-EAFKTAKEPIVVQVLRRTPRTKM-F-TPPSESQLVDTGTQTDITFEHIMALTKMSS PZRN3_HUMAN PZRN3_HUMAN QAV-EAFKTAKEPIVVQVLRRTPRTKM-F-TPPSESQLVDTGTQTDITFEHIMALTKMSS B7ZAC9_HUMAN B7ZAC9_HUMAN QAV-EAFKTAKEPIVVQVLRRTPRTKM-F-TPPSESQLVDTGTQTDITFEHIMALTKMSS B7Z2I8_HUMAN B7Z2I8_HUMAN --------------------------M-F-TPPSESQLVDTGTQTDITFEHIMALTKMSS B7Z5Q3_HUMAN B7Z5Q3_HUMAN QAV-EAFKTAKEPIVVQVLRRTPRTKM-F-TPPSESQLVDTGTQTDITFEHIMALTKMSS PZRN3_RAT PZRN3_RAT QAV-EAFKTAKEPIVVQVLRRTPRTKM-F-TPASESQLVDTGTQTDITFEHIMALTKISS PZRN3_MOUSE PZRN3_MOUSE QAV-EAFKTAKEPIVVQVLRRTPRTKM-F-TPASESQLVDTGTQTDITFEHIMALTKMSS Q3UPS8_MOUSE Q3UPS8_MOUSE QAV-EAFKTAKEPIVVQVLRRTPRTKM-F-TPASESQLVDTGTQTDITFEHIMALTKMSS Q4RSH1_TETNG Q4RSH1_TETNG EAV-EAFRAAKEPVVVQVIRRTPSGRP-H-GPPQEIQVVDVCTQTDITFEHIMALAKLRP Q3UXJ7_MOUSE Q3UXJ7_MOUSE EAV-EAFRTAKEPIVVQVLRRTPLSRP-TYGMTPEVQLTNASTQTDITFEHIMALAKLRP B9EKP7_MOUSE B9EKP7_MOUSE EAV-EAFRTAKEPIVVQVLRRTPLSRP-TYGMTPEVQLTNASTQTDITFEHIMALAKLRP Q69Z24_MOUSE Q69Z24_MOUSE ------------------------------------------------------------ B4DGD1_HUMAN B4DGD1_HUMAN EAV-EAFRNAKEPIVVQVLRRTPLSRP-AYGMASEVQLMNASTQTDITFEHIMALAKLRP PZRN4_HUMAN PZRN4_HUMAN EAV-EAFRNAKEPIVVQVLRRTPLSRP-AYGMASEVQLMNASTQTDITFEHIMALAKLRP B4DG65_HUMAN B4DG65_HUMAN EAV-EAFRNAKEPIVVQVLRRTPLSRP-AYGMASEVQLMNASTQTDITFEHIMALAKLRP Q4RHM6_TETNG Q4RHM6_TETNG GTVAEAIR--RDPIVVQVLRRPPARAA-AEGTLQDVHVTNVCTQTDITFEHIMALAKLRP Q5TYS9_DANRE Q5TYS9_DANRE GTV-EALR--KEPIVVQVLRRGPSSVT---QSLQEVCVVDVCTQTDITFEHIMALAKMRP Q5BLD5_DANRE Q5BLD5_DANRE --------------------------------------------------------GESS Q4T8B3_TETNG Q4T8B3_TETNG ------------------------------------------------------------ B4F6T6_XENTR B4F6T6_XENTR QTL-ETFRASKDPLLIQVLRRSPRMKGTLMTSSHDLQFVDNGTQTDITFEHIMTMGKPRP A2AFG3_MOUSE A2AFG3_MOUSE ------------------------------------------------------------ PDZD4_MOUSE PDZD4_MOUSE QTL-EALRASKEPLVIQVLRRSPRLRG-D-SSCHDLQLVDSGTQTDITFEHIMALGKLRP B7NZP0_RABIT B7NZP0_RABIT QTL-EALRSSKEPLVIQVLRRSPRLRG-D-SSCHDLQLVDSGTQTDITFEHIMALGKLRP B1MTU2_CALMO B1MTU2_CALMO QTL-QALRSSKEPLVIQVLRRSPRLRG-D-SSCHDLQLVDSGTQTDITFEHIMALGKLRP B3KW03_HUMAN B3KW03_HUMAN ----------------------------------------------------MALGKLRP B3KVR9_HUMAN B3KVR9_HUMAN ------------------------------MTA--------------------------- B7ZKY3_HUMAN B7ZKY3_HUMAN ------------------------------------------------------------ Q17RL8_HUMAN Q17RL8_HUMAN QTL-QALRSSKEPLVIQVLRRSPRLRG-D-SSCHDLQLVDSGTQTDITFEHIMALGKLRP PDZD4_HUMAN PDZD4_HUMAN QTL-QALRSSKEPLVIQVLRRSPRLRG-D-SSCHDLQLVDSGTQTDITFEHIMALGKLRP MATCH CONSENSUS ????????????????????????????????????????????????????????????

Q4SR18_TETNG Q4SR18_TETNG SSPQIPELEEYLLPEE----HPSGHAYFDPADFLEGIQQDIER-EEMEYEEVDLYRDNIQ Q6DE42_XENLA Q6DE42_XENLA PSPSVARLDPYLLTEE----HSPAHDYFDPNDFMGGLHPEMDR-DELELEEIDLYRMNSQ B7Z5X9_HUMAN B7Z5X9_HUMAN PSPPV--LDPYLLPEE----HPSAHEYYDPNDYIGDIHQEMDR-EELELEEVDLYRMNSQ B7ZAG0_HUMAN B7ZAG0_HUMAN PSPPV--LDPYLLPEE----HPSAHEYYDPNDYIGDIHQEMDR-EELELEEVDLYRMNSQ B2RWP2_HUMAN B2RWP2_HUMAN PSPPV--LDPYLLPEE----HPSAHEYYDPNDYIGDIHQEMDR-EELELEEVDLYRMNSQ PZRN3_HUMAN PZRN3_HUMAN PSPPV--LDPYLLPEE----HPSAHEYYDPNDYIGDIHQEMDR-EELELEEVDLYRMNSQ B7ZAC9_HUMAN B7ZAC9_HUMAN PSPPV--LDPYLLPEE----HPSAHEYYDPNDYIGDIHQEMDR-EELELEEVDLYRMNSQ B7Z2I8_HUMAN B7Z2I8_HUMAN PSPPV--LDPYLLPEE----HPSAHEYYDPNDYIGDIHQEMDR-EELELEEVDLYRMNSQ B7Z5Q3_HUMAN B7Z5Q3_HUMAN PSPPV--LDPYLLPEE----HPSAHEYYDPNDYIGDIHQEMDR-EELELEEVDLYRMNSQ PZRN3_RAT PZRN3_RAT PSPPV--LGPYLLPEE----HPSSHEYYDPNDYMGDIHQDMDR-EELELEEVGLYRMNSQ PZRN3_MOUSE PZRN3_MOUSE PSPPV--LDPYLLPEE----HPASHDYYDPNDYMGDIHQDMDR-EELELEEVGLYRMNSQ Q3UPS8_MOUSE Q3UPS8_MOUSE PSPPV--LDPYLLPEE----HPASHDYYDPNDYMGDIHQDMDR-EELELEEVGLYRMNSQ Q4RSH1_TETNG Q4RSH1_TETNG STPPVPDVCPFLLSDSCHSLHTMDQDYYEGTDYLSPVPADGERTEEFEYEEVELCRVSSQ Q3UXJ7_MOUSE Q3UXJ7_MOUSE LTPPVPDTCPFLLSDSCHSLHPMEHGFYEDHEYVSSLPADADRADDFEYEEVELCRVSSQ B9EKP7_MOUSE B9EKP7_MOUSE LTPPVPDTCPFLLSDSCHSLHPMDHGFYEDHEYVSSLPADADRADDFEYEEVELCRVSSQ Q69Z24_MOUSE Q69Z24_MOUSE ------------------------------------------------------------ B4DGD1_HUMAN B4DGD1_HUMAN PTPPVPDICPFLLSDSCHSLHPMEHEFYEDNEYISSLPADADRTEDFEYEEVELCRVSSQ PZRN4_HUMAN PZRN4_HUMAN PTPPVPDICPFLLSDSCHSLHPMEHEFYEDNEYISSLPADADRTEDFEYEEVELCRVSSQ B4DG65_HUMAN B4DG65_HUMAN PTPPVPDICPFLLSDSCHSLHPMEHEFYEDNEYISSLPADADRTEDFEYEEVELCRVSSQ Q4RHM6_TETNG Q4RHM6_TETNG ATPPVPDICPFLLSDSCQSIQTMEHEFYECPEYLSNTPAEVERTEEYEYEEVELCRQNSQ Q5TYS9_DANRE Q5TYS9_DANRE STPPVPDICPFLLSDSCHSIQTMEHEYFDCPEYVASTQADVDRAVEFECEEVELCRMNSQ Q5BLD5_DANRE Q5BLD5_DANRE RSPPM------------------------------------------------------- Q4T8B3_TETNG Q4T8B3_TETNG ----------------------------------------------LSYQEVELYKSSQQ B4F6T6_XENTR B4F6T6_XENTR PSPAMVVLEPYVLSEL----PPIGNEFYDQAEYMEGVQPEAERTDELEYEEVELCKSSHQ A2AFG3_MOUSE A2AFG3_MOUSE -------------------------------------------------QEVELCKNSHQ PDZD4_MOUSE PDZD4_MOUSE PTPPMGILEPYVLSEL----PPISHEYYDPAEFMEGGPQEAERMDELEYEEVELCKNSHQ B7NZP0_RABIT B7NZP0_RABIT PTPPLGILEPYVLSEL----PPISHEYYDPAEFMEGGAQEADRMDELEYEEVELYKSSHR B1MTU2_CALMO B1MTU2_CALMO PTPPMVILEPYVLSEL----PPISHEYYDPAEFMEGGPQEADRLDELEYEEVELYKSSHR B3KW03_HUMAN B3KW03_HUMAN PTPPMVILEPYVLSEL----PPISHEYYDPAEFMEGGPQEADRLDELEYEEVELYKSSHR B3KVR9_HUMAN B3KVR9_HUMAN --------------------PPISHEYYDPAEFMEGGPQEADRLDELEYEEVELYKSSHR B7ZKY3_HUMAN B7ZKY3_HUMAN -------------------------------------------------QEVELYKSSHR Q17RL8_HUMAN Q17RL8_HUMAN PTPPMVILEPYVLSEL----PPISHEYYDPAEFMEGGPQEADRLDELEYEEVELYKSSHR PDZD4_HUMAN PDZD4_HUMAN PTPPMVILEP----------PPISHEYYDPAEFMEGGPQEADRLDELEYEEVELYKSSHR MATCH CONSENSUS ??P???????????????????????????????????????R????E?EEV?L??????

Q4SR18_TETNG Q4SR18_TETNG DKLGLTICYRTDDEDEAGIYISE--------------------------IDPNSIAAKDG Q6DE42_XENLA Q6DE42_XENLA DKLGLTVCYRTDDEDDTGIYVSE--------------------------IDPNSIAAKDG B7Z5X9_HUMAN B7Z5X9_HUMAN DKLGLTVCYRTDDEDDIGIYISE--------------------------IDPNSIAAKDG B7ZAG0_HUMAN B7ZAG0_HUMAN DKLGLTVCYRTDDEDDIGIYISE--------------------------IDPNSIAAKDG B2RWP2_HUMAN B2RWP2_HUMAN DKLGLTVCYRTDDEDDIGIYISE--------------------------IDPNSIAAKDG PZRN3_HUMAN PZRN3_HUMAN DKLGLTVCYRTDDEDDIGIYISE--------------------------IDPNSIAAKDG B7ZAC9_HUMAN B7ZAC9_HUMAN DKLGLTVCYRTDDEDDIGIYISE--------------------------IDPNSIAAKDG B7Z2I8_HUMAN B7Z2I8_HUMAN DKLGLTVCYRTDDEDDIGIYISE--------------------------IDPNSIAAKDG B7Z5Q3_HUMAN B7Z5Q3_HUMAN DKLGLTVCYRTDDEDDIGIYISE--------------------------IDPNSIAAKDG PZRN3_RAT PZRN3_RAT DKLGLTVCYRTDDEDDIGIYISE--------------------------IDPNSIAAKDG PZRN3_MOUSE PZRN3_MOUSE DKLGLTVCYRTDDEDDIGIYISE--------------------------IDPNSIAAKDG Q3UPS8_MOUSE Q3UPS8_MOUSE DKLGLTVCYRTDDEDDIGIYISE--------------------------IDPNSIAAKDG Q4RSH1_TETNG Q4RSH1_TETNG EKLGLTLCYRTDEEEDAAIYVSE--------------------------ISPNSIAARDG Q3UXJ7_MOUSE Q3UXJ7_MOUSE EKLGLTVCYRTDDEEDTGIYVSE--------------------------VDPNSIAAKDG B9EKP7_MOUSE B9EKP7_MOUSE EKLGLTVCYRTDDEEDTGIYVSE--------------------------VDPNSIAAKDG Q69Z24_MOUSE Q69Z24_MOUSE ------------------------------------------------------------ B4DGD1_HUMAN B4DGD1_HUMAN EKLGLTVCYRTDDEEDTGIYVSE--------------------------VDPNSIAAKDG PZRN4_HUMAN PZRN4_HUMAN EKLGLTVCYRTDDEEDTGIYVSE--------------------------VDPNSIAAKDG B4DG65_HUMAN B4DG65_HUMAN EKLGLTVCYRTDDEEDTSIYVSE--------------------------VDPNSIAAKDG Q4RHM6_TETNG Q4RHM6_TETNG EKLGLTLCYRTDDEEDTGIYVSQ--------------------------VESNSIAARDG Q5TYS9_DANRE Q5TYS9_DANRE EKLGLTLCYRTDDEEDTAIFVGQ--------------------------VELNSIAARDG Q5BLD5_DANRE Q5BLD5_DANRE --------------------VSE------------------------------------- Q4T8B3_TETNG Q4T8B3_TETNG EKLGLTVCYRTDDEDHLGIYVGEVEHTRPPRMFFESSALKQASHIFTPQVNPNSIAAKNG B4F6T6_XENTR B4F6T6_XENTR DKLGLTVCYRTDDEEDLGIYVGE--------------------------VNPNSIAARDG A2AFG3_MOUSE A2AFG3_MOUSE DKLGLMVCYRTDEEEDLGIYVGE--------------------------VNPNSIAAKDG PDZD4_MOUSE PDZD4_MOUSE DKLGLMVCYRTDEEEDLGIYVGE--------------------------VNPNSIAAKDG B7NZP0_RABIT B7NZP0_RABIT DKLGLMVCYRTDDEDDLGIYVGE--------------------------VNPNSIAAKDG B1MTU2_CALMO B1MTU2_CALMO DKLGLMVCYRTDDEEDLGIYVGE--------------------------VNPNSIAAKDG B3KW03_HUMAN B3KW03_HUMAN DKLGLMVCYRTDDEEDLGIYVGE--------------------------VNPNSIAAKDG B3KVR9_HUMAN B3KVR9_HUMAN DKLGLMVCYRTDDEEDLGIYVGE--------------------------VNPNSIAAKDG B7ZKY3_HUMAN B7ZKY3_HUMAN DKLGLMVCYRTDDEEDLGIYVGE--------------------------VNPNSIAAKDG Q17RL8_HUMAN Q17RL8_HUMAN DKLGLMVCYRTDDEEDLGIYVGE--------------------------VNPNSIAAKDG PDZD4_HUMAN PDZD4_HUMAN DKLGLMVCYRTDDEEDLGIYVGE--------------------------VNPNSIAAKDG MATCH CONSENSUS ?KLGL?VCYRTDDE?D?GIY??E????????????????????????????PNSIAAKDG

Q4SR18_TETNG Q4SR18_TETNG RIREGDKIIQINGVEIQNREDAVALLTREGNQNISLLVARPEIQL-DEGWMDDDRNDFLD Q6DE42_XENLA Q6DE42_XENLA RIREGDRIIQINGIDVNNYEEAVNLLTSEDTKNVFLLVARPELQL-DEGWMDDDRNDFLD B7Z5X9_HUMAN B7Z5X9_HUMAN RIREGDCIIQINGIEVQNREEAVALLTSEENKNFSLLIARPELQL-DEGWMDDDRNDFLD B7ZAG0_HUMAN B7ZAG0_HUMAN RIREGDRIIQINGIEVQNREEAVALLTSEENKNFSLLIARPELQL-DEGWMDDDRNDFLD B2RWP2_HUMAN B2RWP2_HUMAN RIREGDRIIQINGIEVQNREEAVALLTSEENKNFSLLIARPELQL-DEGWMDDDRNDFLD PZRN3_HUMAN PZRN3_HUMAN RIREGDRIIQINGIEVQNREEAVALLTSEENKNFSLLIARPELQL-DEGWMDDDRNDFLD B7ZAC9_HUMAN B7ZAC9_HUMAN RIREGDRIIQINGIEVQNREEAVALLTSEENKNFSLLIARPELQL-DEGWMDDDRNDFLD B7Z2I8_HUMAN B7Z2I8_HUMAN RIREGDRIIQINGIEVQNREEAVALLTSEENKNFSLLIARPELQL-DEGWMDDDRNDFLD B7Z5Q3_HUMAN B7Z5Q3_HUMAN RIREGDRIIQINGIEVQNREEAVALLTSEENKNFSLLIARPELQL-DEGWMDDDRNDFLD PZRN3_RAT PZRN3_RAT RIREGDRIIQINGIEVQNREEAVALLTSEENKNFSLLIARPELQL-DEGWMDDDRNDFLD PZRN3_MOUSE PZRN3_MOUSE RIREGDRIIQINGIEVQNREEAVALLTSEENKNFSLLIARPELQL-DEGWMDDDRNDFLD Q3UPS8_MOUSE Q3UPS8_MOUSE RIREGDRIIQINGIEVQNREEAVALLTSEENKNFSLLIARPELQL-DEGWMDDDRNDFLD Q4RSH1_TETNG Q4RSH1_TETNG RIREGDRILQINGQDVQNRQEAVAALSSDECTSIVLLVARPETQL-EEAWLDDEHSEFLE Q3UXJ7_MOUSE Q3UXJ7_MOUSE RIREGDRILQINGEDIQNREEAVALLSSDECKRIVLLIARPDMQL-DEGWLEDERNEFLE B9EKP7_MOUSE B9EKP7_MOUSE RIREGDRILQINGEDIQNREEAVALLSSDECKRIVLLIARPDMQL-DEGWLEDERNEFLE Q69Z24_MOUSE Q69Z24_MOUSE ------------------------------------------------------------ B4DGD1_HUMAN B4DGD1_HUMAN RIREGDRILQINGEDVQNREEAVALLSNDECKRIVLLVARPEIQL-DEGWLEDERNEFLE PZRN4_HUMAN PZRN4_HUMAN RIREGDRILQINGEDVQNREEAVALLSNDECKRIVLLVARPEIQL-DEGWLEDERNEFLE B4DG65_HUMAN B4DG65_HUMAN RIREGDRILQINGEDVQNREEAVALLSNDECKRIVLLVARPEIQL-DEGWLEDERNEFLE Q4RHM6_TETNG Q4RHM6_TETNG RIKQGDRILQINGCEVQDRGRAVALLSSEDARSIVLLVTRPEIQLEEEAWLDENQEELVE Q5TYS9_DANRE Q5TYS9_DANRE RIREGDRILQINGRDVQNREEAVALLSNENSRSIVLLVTRPEGQM-DGNWLDEDHHDFLE Q5BLD5_DANRE Q5BLD5_DANRE ------------------------------------------------------------ Q4T8B3_TETNG Q4T8B3_TETNG RIREGDRIVQINGVDIQNRDEAVAILTREDSVNFSLLLARPDVE--SENVGEKDIEMSLD B4F6T6_XENTR B4F6T6_XENTR RIREGDRILQINGMDVQNREEAVAILTQEESTNISLLVARPETEM-GRRWKDSDREDFLD A2AFG3_MOUSE A2AFG3_MOUSE RIREGDRIIQINGMDVQNREEAVAILSQEENTNISLLVARPESQL-AKRWKDSDRDDFLD PDZD4_MOUSE PDZD4_MOUSE RIREGDRIIQINGMDVQNREEAVAILSQEENTNISLLVARPESQL-AKRWKDSDRDDFLD B7NZP0_RABIT B7NZP0_RABIT RIREGDRIIQINGVDVQNREEAVAILSQEENTNISLLVARPESQL-AKRWKDSDRDDFLD B1MTU2_CALMO B1MTU2_CALMO RIREGDRIIQINGVDVQNREEAVAILSQEENTNISLLVARPESQL-AKRWKDSDRDDFLD B3KW03_HUMAN B3KW03_HUMAN RIREGDRIIQINGVDVQNREEAVAILSQEENTNISLLVARPESQL-AKRWKDSDRDDFLD B3KVR9_HUMAN B3KVR9_HUMAN RIREGDRIIQINGVDVQNREEAVAILSQEENTNISLLVARPESQL-AKRWKDSDRDDFLD B7ZKY3_HUMAN B7ZKY3_HUMAN RIREGDRIIQINGVDVQNREEAVAILSQEENTNISLLVARPESQL-AKRWKDSDRDDFLD Q17RL8_HUMAN Q17RL8_HUMAN RIREGDRIIQINGVDVQNREEAVAILSQEENTNISLLVARPESQL-AKRWKDSDRDDFLD PDZD4_HUMAN PDZD4_HUMAN RIREGDRIIQINGVDVQNREEAVAILSQEENTNISLLVARPESQL-AKRWKDSDRDDFLD MATCH CONSENSUS RIREGDRI?QING??VQNREEAVA?L?????????LL?ARPE?QL????W????R??FL?

Q4SR18_TETNG Q4SR18_TETNG ----------DLHMDMLEQQHHQAMQFTA----SMLQQKKHEE-DGG---------TTDT Q6DE42_XENLA Q6DE42_XENLA ----------DLHMDMLEEQHHQAMQFTA----SMLQQKKLEE-DGG---------TTDT B7Z5X9_HUMAN B7Z5X9_HUMAN ----------DLHMDMLEEQHHQAMQFTA----SVLQQKKHDE-DGG---------TTDT B7ZAG0_HUMAN B7ZAG0_HUMAN ----------DLHMDMLEEQHHQAMQFTA----SVLQQKKHDE-DGG---------TTDT B2RWP2_HUMAN B2RWP2_HUMAN ----------DLHMDMLEEQHHQAMQFTA----SVLQQKKHDE-DGG---------TTDT PZRN3_HUMAN PZRN3_HUMAN ----------DLHMDMLEEQHHQAMQFTA----SVLQQKKHDE-DGG---------TTDT B7ZAC9_HUMAN B7ZAC9_HUMAN ----------DLHMDMLEEQHHQAMQFTA----SVLQQKKHDE-DGG---------TTDT B7Z2I8_HUMAN B7Z2I8_HUMAN ----------DLHMDMLEEQHHQAMQFTA----SVLQQKKHDE-DGG---------TTDT B7Z5Q3_HUMAN B7Z5Q3_HUMAN ----------DLHMDMLEEQHHQAMQFTA----SVLQQKKHDE-DGG---------TTDT PZRN3_RAT PZRN3_RAT ----------DLHMDMLEEQHHQAMQFTA----SVLQQKKHEE-DGG---------TTDT PZRN3_MOUSE PZRN3_MOUSE ----------DLHMDMLEEQHHQAMQFTA----SVLQQKKHEE-DGG---------TTDT Q3UPS8_MOUSE Q3UPS8_MOUSE ----------DLHMDMLEEQHHQAMQFTA----SVLQQKKHEE-DGG---------TTDT Q4RSH1_TETNG Q4RSH1_TETNG ----------QLKMEMLEEQQREEMELAA---------------------------LQEA Q3UXJ7_MOUSE Q3UXJ7_MOUSE ----------ELNSELLEEDHNEGAQRTA----SELQQPKKQEEEEG---------TTDT B9EKP7_MOUSE B9EKP7_MOUSE ----------ELNSELLEEDHNEGAQRTA----SELQQPKKQEEEEG---------TTDT Q69Z24_MOUSE Q69Z24_MOUSE --------------------------------------------EEG---------TTDT B4DGD1_HUMAN B4DGD1_HUMAN ----------ELNLEMLEEEHNEAMQPTA----NEVEQPKKQEEEEG---------TTDT PZRN4_HUMAN PZRN4_HUMAN ----------ELNLEMLEEEHNEAMQPTA----NEVEQPKKQEEEEG---------TTDT B4DG65_HUMAN B4DG65_HUMAN ----------ELNLEMLEEEHNEAMQPTA----NEVEQPKKQEEEEG---------TTDT Q4RHM6_TETNG Q4RHM6_TETNG ----------ELKMEILEERRNKVEKHRS----R---ENEHQAEEEI---------TTDS Q5TYS9_DANRE Q5TYS9_DANRE ----------ELKMEILEEQKKEGILQTA----GCMKLSTRQE--DA---------STDT Q5BLD5_DANRE Q5BLD5_DANRE ---------------------------------HRLPVSQQDE-------------STSP Q4T8B3_TETNG Q4T8B3_TETNG GGGESACSRNSSHLSGYYRLYQEARQRDSAGGHADMEEEEEEEEEEGERGEHEDRPVPLP B4F6T6_XENTR B4F6T6_XENTR ----------DLVSDNEEEL--QAQRLNS----PPQQQAENEDAEAS---------PKSP A2AFG3_MOUSE A2AFG3_MOUSE ----------DFGSENEGDL--RARKLKS----PPVQQIGNDE--KG---------APDG PDZD4_MOUSE PDZD4_MOUSE ----------DFGSENEGDL--RARKLKS----PPVQQIGNDE--KG---------APDG B7NZP0_RABIT B7NZP0_RABIT ----------DFGSENEGDL--RARKLKS----PPAQQPGNEE-EKG---------APDG B1MTU2_CALMO B1MTU2_CALMO ----------DFGSENEGEL--RARKLKS----PPAQQLGNEE-EKG---------APDA B3KW03_HUMAN B3KW03_HUMAN ----------DFGSENEGEL--RARKLKS----PPAQQPGNEE-EKG---------APDA B3KVR9_HUMAN B3KVR9_HUMAN ----------DFGSENEGEL--RARKLKS----PPAQQPGNEE-EKG---------APDA B7ZKY3_HUMAN B7ZKY3_HUMAN ----------DFGSENEGEL--RARKLKS----PPAQQPGNEE-EKG---------APDA Q17RL8_HUMAN Q17RL8_HUMAN ----------DFGSENEGEL--RARKLKS----PPAQQPGNEE-EKG---------APDA PDZD4_HUMAN PDZD4_HUMAN ----------DFGSENEGEL--RARKLKS----PPAQQPGNEE-EKG---------APDA MATCH CONSENSUS ?????????????????????????????????????Q????E???G???????????D?

Q4SR18_TETNG Q4SR18_TETNG -----ATLLSNHHEKDSGVGRTDES----TRNDESSEQENLGDDQTT----ASNTLGSCR Q6DE42_XENLA Q6DE42_XENLA -----ATLLSNHLEKDSGIGRTDES----TRNDESSEQENLADDHTT--------LGSHK B7Z5X9_HUMAN B7Z5X9_HUMAN -----ATILSNQHEKDSGVGRTDES----TRNDESSEQENNGDDATA----SSNPLAGQR B7ZAG0_HUMAN B7ZAG0_HUMAN -----ATILSNQHEKDSGVGRTDES----TRNDESSEQENNGDDATA----SSNPLAGQR B2RWP2_HUMAN B2RWP2_HUMAN -----ATILSNQHEKDSGVGRTDES----TRNDESSDQENNGDDATA----SSNPLAGQR PZRN3_HUMAN PZRN3_HUMAN -----ATILSNQHEKDSGVGRTDES----TRNDESSEQENNGDDATA----SSNPLAGQR B7ZAC9_HUMAN B7ZAC9_HUMAN -----ATILSNQHEKDSGVGRTDES----TRNDESSEQENNGDDATA----SSNPLAGQR B7Z2I8_HUMAN B7Z2I8_HUMAN -----ATILSNQHEKDSGVGRTDES----TRNDESSEQENNGDDATA----SSNPLAGQR B7Z5Q3_HUMAN B7Z5Q3_HUMAN -----ATILSNQHEKDSGVGRTDES----TRNDESSEQENNGDDATA----SSNPLAGQR PZRN3_RAT PZRN3_RAT -----ATILSNQHEKDSGVGRTDES----TRNDESSEQENNGEDATA----SSNPLAGQR PZRN3_MOUSE PZRN3_MOUSE -----ATILSNQHEKDSGVGRTDES----TRNDESSEQENNGEDATA----SANPLAGQR Q3UPS8_MOUSE Q3UPS8_MOUSE -----ATILSNQHEKDSGVGRTDES----TRNDESSEQENNGEDATA----SANPLAGQR Q4RSH1_TETNG Q4RSH1_TETNG ------------------------------------------------------------ Q3UXJ7_MOUSE Q3UXJ7_MOUSE -----ATSSSNNQEKDSGVGRTDES----LRNDESSEQENAVEEP------HSTTLKSKR B9EKP7_MOUSE B9EKP7_MOUSE -----ATSSSNNQEKDSGVGRTDES----LRNDESSEQENAVEEP------HSTTLKSKR Q69Z24_MOUSE Q69Z24_MOUSE -----ATSSSNNQEKDSGVGRTDES----LRNDESSEQENAVEEP------HSTTLKSKR B4DGD1_HUMAN B4DGD1_HUMAN -----ATSSSNNHEKDSGVGRTDES----LRNDESSEQENAAEDP------NSTSLKSKR PZRN4_HUMAN PZRN4_HUMAN -----ATSSSNNHEKDSGVGRTDES----LRNDESSEQENAAEDP------NSTSLKSKR B4DG65_HUMAN B4DG65_HUMAN -----ATSSSNNHEKDSGVGRTDES----LRNDESSEQENAAEDP------NSTSLKSKR Q4RHM6_TETNG Q4RHM6_TETNG -----ATCSSNNQDKDSGFGHSPEHQPLLVRASQAKPAHLLRDRW------RAEHPQMRR Q5TYS9_DANRE Q5TYS9_DANRE -----ATCSSSILEKDSGMKCSF---------EESSEHEFL------------SYPRTQK Q5BLD5_DANRE Q5BLD5_DANRE -----LPSRHRDRPMWSERGRASLN--------------------------STYSPSSYK Q4T8B3_TETNG Q4T8B3_TETNG PLLSLAPLLCNSQDLDSGVGRTDDS----TRYEESSEHDLLGDQTSAPNTNTTNTPGSTR B4F6T6_XENTR B4F6T6_XENTR RPFPHPAGLSRSQELDSGVGRTDES----TRNDESSEHDLLGDDQTS----SANTPGSQR A2AFG3_MOUSE A2AFG3_MOUSE -----GPGLNNSQDLDSGVGRTDES----TRNEESSEHDLLGDEPPS----TTNTPGSLR PDZD4_MOUSE PDZD4_MOUSE -----GPGLNNSQDLDSGVGRTDES----TRNEESSEHDLLGDEPPS----TTNTPGSLR B7NZP0_RABIT B7NZP0_RABIT -----GPGLSNSQELDSGVGRTDES----TRNEESSEHDLLGDEPPS----STNTPGSLR B1MTU2_CALMO B1MTU2_CALMO -----GPGLSNSQELDSGVGRTDES----TRNEESSEHDLLGDEPPS----STNTPGSLR B3KW03_HUMAN B3KW03_HUMAN -----GPGLSNSQELDSGVGRTDES----TRNEESSEHDLLGDEPPS----STNTPGSLR B3KVR9_HUMAN B3KVR9_HUMAN -----GPGLSNSQELDSGVGRTDES----TRNEESSEHDLLGDEPPS----STNTPGSLR B7ZKY3_HUMAN B7ZKY3_HUMAN -----GPGLSNSQELDSGVGRTDES----TRNEESSEHDLLGDEPPS----STNTPGSLR Q17RL8_HUMAN Q17RL8_HUMAN -----GPGLSNSQELDSGVGRTDES----TRNEESSEHDLLGDEPPS----STNTPGSLR PDZD4_HUMAN PDZD4_HUMAN -----GPGLSNSQELDSGVGRTDES----TRNEESSEHDLLGDEPPS----STNTPGSLR MATCH CONSENSUS ?????????SN??E?DSGVGRTDES?????RN?ESSE??????????????????????R

Q4SR18_TETNG Q4SR18_TETNG KL----NYSQDTLGSSDLP--FSGESFI--SVDYADADF--------------------- Q6DE42_XENLA Q6DE42_XENLA KL----MYSQDTLGSGDMQ--FSNESFI--SADCTDADF--------------------- B7Z5X9_HUMAN B7Z5X9_HUMAN KL----TCSQDTLGSGDLP--FSNESFI--SADCTDADY--------------------- B7ZAG0_HUMAN B7ZAG0_HUMAN KL----TCSQDTLGSGDLP--FSNESFI--SADCTDADY--------------------- B2RWP2_HUMAN B2RWP2_HUMAN KL----TCSQDTLGSGDLP--FSNESFI--SADCTDADY--------------------- PZRN3_HUMAN PZRN3_HUMAN KL----TCSQDTLGSGDLP--FSNESFI--SADCTDADY--------------------- B7ZAC9_HUMAN B7ZAC9_HUMAN KL----TCSQDTLGSGDLP--FSNESFI--SADCTDADY--------------------- B7Z2I8_HUMAN B7Z2I8_HUMAN KL----TCSQDTLGSGDLP--FSNESFI--SADCTDADY--------------------- B7Z5Q3_HUMAN B7Z5Q3_HUMAN KL----TCSQDTLGSGDLP--FSNESFI--SADCTDADY--------------------- PZRN3_RAT PZRN3_RAT KL----TCSQDTLGSGDLP--FSNESFI--SADCTDVDY--------------------- PZRN3_MOUSE PZRN3_MOUSE KL----TCSQDTLGSGDLP--FSNESFI--SADCTDVDY--------------------- Q3UPS8_MOUSE Q3UPS8_MOUSE KL----TCSQDTLGSGDLP--FSNESFI--SADCTDVDY--------------------- Q4RSH1_TETNG Q4RSH1_TETNG ------------------------------------------------------------ Q3UXJ7_MOUSE Q3UXJ7_MOUSE EL----GKSQDTLGSLEHQ---CSESCA--GGECLDSDC--------------------- B9EKP7_MOUSE B9EKP7_MOUSE EL----GKSQDTLGSLEHQ---CSESCA--GGECLDSDC--------------------- Q69Z24_MOUSE Q69Z24_MOUSE EL----GKSQDTLGSLEHQ---CSESCA--GGECLDSDC--------------------- B4DGD1_HUMAN B4DGD1_HUMAN DL----GQSQDTLGSVELQ--Y-NESLV--SGEYIDSDC--------------------- PZRN4_HUMAN PZRN4_HUMAN DL----GQSQDTLGSVELQ---YNESLV--SGEYIDSDC--------------------- B4DG65_HUMAN B4DG65_HUMAN DL----GQSQDTLGSVELQ--Y-NESLV--SGEYIDSDC--------------------- Q4RHM6_TETNG Q4RHM6_TETNG SL----SVAQDTHGQRTLSKGQGHEGVI--SIRNSGGGI--------------------- Q5TYS9_DANRE Q5TYS9_DANRE QL----R---DRWEASSHL--VPMDTM---QEKKGQDNR--------------------- Q5BLD5_DANRE Q5BLD5_DANRE KF--------QTITPMNQK--FCSLSREGTVRRMPD------------------------ Q4T8B3_TETNG Q4T8B3_TETNG KF-----RVGASPSQRELQ--PSYDSLSGMDWAAGGGAYSPLHHHQLKHHLRLHQPMLMM B4F6T6_XENTR B4F6T6_XENTR RLRFLRGDSQHPLQCREFH--HSLDSLLAADGSVPYNEV------------------LPP A2AFG3_MOUSE A2AFG3_MOUSE KF----GLQGDALQSRDFH--FSMDSLLAEGAGLGGADL--------------------- PDZD4_MOUSE PDZD4_MOUSE KF----GLQGDALQSRDFH--FSMDSLLAEGAGLGGADL--------------------- B7NZP0_RABIT B7NZP0_RABIT KF----GLQGDMLQSRDFH--FSMDSLLAEGAGLAGGDV--------------------- B1MTU2_CALMO B1MTU2_CALMO KF----GLQGDALQSRDFH--FSMDSLLAEGAGLGGSDV--------------------- B3KW03_HUMAN B3KW03_HUMAN KF----GLQGDALQSRDFH--FSMDSLLAEGAGLGGGDV--------------------- B3KVR9_HUMAN B3KVR9_HUMAN KF----GLQGDALQSRDFH--FSMDSLLAEGAGLGGGDV--------------------- B7ZKY3_HUMAN B7ZKY3_HUMAN KF----GLQGDALQSRDFH--FSMDSLLAEGAGLGGGDV--------------------- Q17RL8_HUMAN Q17RL8_HUMAN KF----GLQGDALQSRDFH--FSMDSLLAEGAGLGGGDV--------------------- PDZD4_HUMAN PDZD4_HUMAN KF----GLQGDALQSRDFH--FSMDSLLAEGAGLGGGDV--------------------- MATCH CONSENSUS ??????????D?L?S??????????S???????????D??????????????????????

Q4SR18_TETNG Q4SR18_TETNG -LGITADECERFRELLELKCQMRNGGAQS----LCCQ-----------GAGQ-----DQE Q6DE42_XENLA Q6DE42_XENLA -LGIPMDECERFRELLELKCQVQSSNQQS----RYYQ-----SSTME-TNRS-----DQE B7Z5X9_HUMAN B7Z5X9_HUMAN -LGIPVDECERFRELLELKCQVKSATPYG----LYYP-----SGPLD-AGKS-----DPE B7ZAG0_HUMAN B7ZAG0_HUMAN -LGIPVDECERFRELLELKCQVKSATPYG----LYYP-----SGPLD-AGKS-----DPE B2RWP2_HUMAN B2RWP2_HUMAN -LGIPVDECERFRELLELKCQVKSATPYG----LYYP-----SGPLD-AGKS-----DPE PZRN3_HUMAN PZRN3_HUMAN -LGIPVDECERFRELLELKCQVKSATPYG----LYYP-----SGPLD-AGKS-----DPE B7ZAC9_HUMAN B7ZAC9_HUMAN -LGITVDECERFRELLELKCQVKSATPYG----LYYP-----SGPLD-AGKS-----DPE B7Z2I8_HUMAN B7Z2I8_HUMAN -LGIPVDECERFRELLELKCQVKSATPYG----LYYP-----SGPLD-AGKS-----DPE B7Z5Q3_HUMAN B7Z5Q3_HUMAN -LGIPVDECERFRELLELKCQVKSATPYG----LYYP-----SGPLD-AGKS-----DPE PZRN3_RAT PZRN3_RAT -LGIPEDECERFRELLELKCQVQSTSPYS----LYYP-----SSPLDAAGKG-----DPE PZRN3_MOUSE PZRN3_MOUSE -LGIPEDECERFRELLELKCQVQSASPYS----LYYP-----SSPLDAAGKS-----DPE Q3UPS8_MOUSE Q3UPS8_MOUSE -LGIPEDECERFRELLELKCQVQSASPYS----LYYP-----SSPLDAAGKS-----DPE Q4RSH1_TETNG Q4RSH1_TETNG ------QEYE--QQLLELKCQIRNSGEYD----LFYS-----RSTIE-CSVG-----EQD Q3UXJ7_MOUSE Q3UXJ7_MOUSE --ASNQEVCEGFQQLLELK--IRNHGDYD----LYYS-----SSTIE-CNRG-----EQD B9EKP7_MOUSE B9EKP7_MOUSE --ASNQEVCEGFQQLLELK--IRNHGDYD----LYYS-----SSTIE-CNRG-----EQD Q69Z24_MOUSE Q69Z24_MOUSE --ASNQEVCEGFQQLLELK--IRNHGDYD----LYYS-----SSTIE-CNRG-----EQD B4DGD1_HUMAN B4DGD1_HUMAN -IGNPDEDCERFRQLLELKCKIRNHGEYD----LYYS-----SSTIE-CNQG-----EQE PZRN4_HUMAN PZRN4_HUMAN -IGNPDEDCERFRQLLELKCKIRNHGEYD----LYYS-----SSTIE-CNQG-----EQE B4DG65_HUMAN B4DG65_HUMAN -IGNPDEDCERFRQLLELKCKIRNHGEYD----LYYS-----SSTIE-CNQG-----EQE Q4RHM6_TETNG Q4RHM6_TETNG -LGL--ENC--FQQLLELKCQIRNGGECG----VYSIRHSIECSLSEQGGKDRNDVEDVG Q5TYS9_DANRE Q5TYS9_DANRE -LSENGVECDHFQQLLELKCQIRNGGECG----LVYRR----SSTIE-CSLT-----EQG Q5BLD5_DANRE Q5BLD5_DANRE --GMAQNSSSR------VNNHTRNGGRSAESS-PYFT----------------------- Q4T8B3_TETNG Q4T8B3_TETNG MPGLTEEEFQRYEELLDIRCQYERHKQQSQATKISLDDRKVQEGDEE-EGRGMAREEEEA B4F6T6_XENTR B4F6T6_XENTR AAGLTDEEYERYRELLEITCHLENGNGPA----FLYA---SRQGGLD-VNRN-------E A2AFG3_MOUSE A2AFG3_MOUSE -PGLTDEEYERYRELLEIKCHLENGNQLG----IFFSRASSGNSALD-VNRN-------E PDZD4_MOUSE PDZD4_MOUSE -PGLTDEEYERYRELLEIKCHLENGNQLG----IFFSRASSGNSALD-VNRN-------E B7NZP0_RABIT B7NZP0_RABIT -PGLTDEEYERYRELLEIKCHLENGNPLG----LLFPRASGGNSALD-VNRN-------E B1MTU2_CALMO B1MTU2_CALMO -PGLTDEEYERYRELLEIKCHLENGNQLG----LLFPRASAGNSALD-VNRN-------E B3KW03_HUMAN B3KW03_HUMAN -PGLTDEEYERYRELLEIKCHLENGNQLG----LLFPRASGGNSALD-VNRN-------E B3KVR9_HUMAN B3KVR9_HUMAN -PGLTDEEYERYRELLEIKCHLENGNQLG----LLFPRASGGNSALD-VNRN-------E B7ZKY3_HUMAN B7ZKY3_HUMAN -PGLTDEEYERYRELLEIKCHLENGNQLG----LLFPRASGGNSALD-VNRN-------E Q17RL8_HUMAN Q17RL8_HUMAN -PGLTDEEYERYRELLEIKCHLENGNQLG----LLFPRASGGNSALD-VNRN-------E PDZD4_HUMAN PDZD4_HUMAN -PGLTDEEYERYRELLEIKCHLENGNQLG----LLFPRASGGNSALD-VNRN-------E MATCH : . CONSENSUS ??G??????ER???LLE?KC????????????????????????????????????????

Q4SR18_TETNG Q4SR18_TETNG ---GV-----------DKELELLNEELRTIELECLNIVRAHKMQLLKEQ------CRESW Q6DE42_XENLA Q6DE42_XENLA ---SV-----------DRELEMLNEELHSIELECLNIVRAHKMQQLKDQ------YRDSW B7Z5X9_HUMAN B7Z5X9_HUMAN ---SV-----------DKELELLNEELRSIELECLSIVRAHKMQQLKEQ------YRESW B7ZAG0_HUMAN B7ZAG0_HUMAN ---SV-----------DKELELLNEELRSIELECLSIVRAHKMQQLKEQ------YRESW B2RWP2_HUMAN B2RWP2_HUMAN ---SV-----------DKELELLNEELRSIELECLSIVRAHKMQQLKEQ------YRESW PZRN3_HUMAN PZRN3_HUMAN ---SV-----------DKELELLNEELRSIELECLSIVRAHKMQQLKEQ------YRESW B7ZAC9_HUMAN B7ZAC9_HUMAN ---SV-----------DKELELLNEELRSIELECLSIVRAHKMQQLKEQ------YRESW B7Z2I8_HUMAN B7Z2I8_HUMAN ---SV-----------DKELELLNEELRSIELECLSIVRAHKMQQLKEQ------YRESW B7Z5Q3_HUMAN B7Z5Q3_HUMAN ---SV-----------DKELELLNEELRSIELECLSIVRAHKMQQLKEQ------YRESW PZRN3_RAT PZRN3_RAT ---SV-----------DKELELLNEELRSIELECLSIVRAHKMQQLKEQ------YRESW PZRN3_MOUSE PZRN3_MOUSE ---SV-----------DKELELLNEELRSIELECLSIVRAHKMQQLKEQ------YRESW Q3UPS8_MOUSE Q3UPS8_MOUSE ---SV-----------DKELELLNEELRSIELECLSIVRAHKMQQLKEQ------YRESW Q4RSH1_TETNG Q4RSH1_TETNG ---SV-----------QHELRMLNEELRSI------------------------------ Q3UXJ7_MOUSE Q3UXJ7_MOUSE ---GV-----------EHELQLLNEELRNIELECQNIMQAHRLQKVTDQ------YGDIW B9EKP7_MOUSE B9EKP7_MOUSE ---GV-----------EHELQLLNEELRNIELECQNIMQAHRLQKVTDQ------YGDIW Q69Z24_MOUSE Q69Z24_MOUSE ---GV-----------EHELQLLNEELRNIELECQNIMQAHRLQKVTDQ------YGDIW B4DGD1_HUMAN B4DGD1_HUMAN ---GV-----------EHELQLLNEELRNIELECQNIMQAHRLQKVTDQ------YGDIW PZRN4_HUMAN PZRN4_HUMAN ---GV-----------EHELQLLNEELRNIELECQNIMQAHRLQKVTDQ------YGDIW B4DG65_HUMAN B4DG65_HUMAN ---GV-----------EHELQLLNEELRNIELECQNIMQAHRLQKVTDQ------YGDIW Q4RHM6_TETNG Q4RHM6_TETNG EGSGV-----------EQELKMLNEELRNIELECQSIMQAHQLRKSHQRDYIDPLSSPGW Q5TYS9_DANRE Q5TYS9_DANRE GS-GV-----------ARELHMLNEELRSIELECQSIMQAHQLRRSK--------HDSPR Q5BLD5_DANRE Q5BLD5_DANRE ---------------------------RRRHSNCFT----------PER------YQSCM Q4T8B3_TETNG Q4T8B3_TETNG LLSSTAADVNCNTTVSEHEMALIDEELRHLEFKCRNILRAQKMQQLRER------CLKAW B4F6T6_XENTR B4F6T6_XENTR ---SV-----------LREMAVLEEELRHLEFKFRNVLRAQKMQQLRER------CMKAW A2AFG3_MOUSE A2AFG3_MOUSE ---SL-----------GHEMAMLEEELRHLEFKCRNILRAQKMQQLRER------CMKAW PDZD4_MOUSE PDZD4_MOUSE ---SL-----------GHEMAMLEEELRHLEFKCRNILRAQKMQQLRER------CMKAW B7NZP0_RABIT B7NZP0_RABIT ---SL-----------GHEMAMLEEELRHLEFKCRNILRAQKMQQLRER------CMKAW B1MTU2_CALMO B1MTU2_CALMO ---SL-----------GHEMAMLEEELRHLEFKCRNILRAQKMQQLRER------CMKAW B3KW03_HUMAN B3KW03_HUMAN ---SL-----------GHEMAMLEEELRHLEFKCRNILRAQKMQQLRER------CMKAW B3KVR9_HUMAN B3KVR9_HUMAN ---SL-----------GHEMAMLEEELRHLEFKCRNILRAQKMQQLRER------CMKAW B7ZKY3_HUMAN B7ZKY3_HUMAN ---SL-----------GHEMAMLEEELRHLEFKCRNILRAQKMQQLRER------CMKAW Q17RL8_HUMAN Q17RL8_HUMAN ---SL-----------GHEMAMLEEELRHLEFKCRNILRAQKMQQLRER------CMKAW PDZD4_HUMAN PDZD4_HUMAN ---SL-----------GHEMAMLEEELRHLEFKCRNILRAQKMQQLRER------CMKAW MATCH : CONSENSUS ??????????????????E???L?EELR??E??C??I??A???Q???????????????W

Q4SR18_TETNG Q4SR18_TETNG MLHDS-GFR-NYN--TSIDARRHELSDITELPEKS------DKDSSSAYNT-GESCRSTP Q6DE42_XENLA Q6DE42_XENLA MLHNS-GFH-NYN--TSIDVRRHELSDITELPEKS------DKDSSSAYNT-GESCRSTP B7Z5X9_HUMAN B7Z5X9_HUMAN MLHNS-GFR-NYN--TSIDVRRRELSDITELPEKS------DKDSSSAYNT-GESCRSTP B7ZAG0_HUMAN B7ZAG0_HUMAN MLHNS-GFR-NYN--TSIDVRRHELSDITELPEKS------DKDSSSAYNT-GESCRSTP B2RWP2_HUMAN B2RWP2_HUMAN MLHNS-GFR-NYN--TSIDVRRHELSDITELPEKS------DKDSSSAYNT-GESCRSTP PZRN3_HUMAN PZRN3_HUMAN MLHNS-GFR-NYN--TSIDVRRHELSDITELPEKS------DKDSSSAYNT-GESCRSTP B7ZAC9_HUMAN B7ZAC9_HUMAN MLHNS-GFR-NYN--TSIDVRRHELSDITELPEKS------DKDSSSAYNT-GESCRSTP B7Z2I8_HUMAN B7Z2I8_HUMAN MLHNS-GFR-NYN--TSIDVRRHELSDITELPEKS------DKDSSSAYNT-GESCRSTP B7Z5Q3_HUMAN B7Z5Q3_HUMAN MLHNS-GFR-NYN--TSIDVRRHELSDITELPEKS------DKDSSSAYNT-GESCRSTP PZRN3_RAT PZRN3_RAT MLHHS-GFR-NYN--TSVDVRRHELSDITELPEKS------DKDSSSAYNT-GESCRSTP PZRN3_MOUSE PZRN3_MOUSE MLHHS-GFR-NYN--TSVDVRRHELSDITELPEKS------DKDSSSAYNT-GESCRSTP Q3UPS8_MOUSE Q3UPS8_MOUSE MLHHS-GFR-NYN--TSVDVRRHELSDITELPEKS------DKDSSSAYNT-GESCRSTP Q4RSH1_TETNG Q4RSH1_TETNG ------GAG------VSQRGETTKLTDTNDRLEKS------DKDSSSAYNT-AESSRSTP Q3UXJ7_MOUSE Q3UXJ7_MOUSE ALHDG-GFR-NYN--TSLDVQRGKLDDIMEHPEKS------DKDSSSAYNT-AESCRSTP B9EKP7_MOUSE B9EKP7_MOUSE ALHDG-GFR-NYN--TSLDVQRGKLDDIMEHPEKS------DKDSSSAYNT-AESCRSTP Q69Z24_MOUSE Q69Z24_MOUSE ALHDG-GFR-NYN--TSLDVQRGKLDDIMEHPEKS------DKDSSSAYNT-AESCRSTP B4DGD1_HUMAN B4DGD1_HUMAN TLHDG-GFR-NYN--TSIDMQRGKLDDIMEHPEKS------DKDSSSAYNT-AESCRSTP PZRN4_HUMAN PZRN4_HUMAN TLHDG-GFR-NYN--TSIDMQRGKLDDIMEHPEKS------DKDSSSAYNT-AESCRSTP B4DG65_HUMAN B4DG65_HUMAN TLHDG-GFR-NYN--TSIDMQRGKLDDIMEHPEKS------DKDSSSAYNT-AESCRSTP Q4RHM6_TETNG Q4RHM6_TETNG SPKES-------------HKQHGRLADIHEYPERSDGDKVREKDSSSAYNT-AESARSTP Q5TYS9_DANRE Q5TYS9_DANRE MDKEN-------------RLRRGKLADINEHPERLQSEKLRDKDSSSAYNT-AESSRSTP Q5BLD5_DANRE Q5BLD5_DANRE HLGSS-------------------------HSESS-----------------G------- Q4T8B3_TETNG Q4T8B3_TETNG MMEESMTAQAGLDNDDEDDPHHHELSAINELPERSD-----DKDTSSAYNTGGESCWSTP B4F6T6_XENTR B4F6T6_XENTR LMEEEDSLY-DFGGGTANNEASTKLPDITELPERS------DKDSTSAYNT-GESCRSTP A2AFG3_MOUSE A2AFG3_MOUSE LLEEE-SLY-DL---AASEPKKHELSDISELPEKS------DKDSTSAYNT-GESCRSTP PDZD4_MOUSE PDZD4_MOUSE LLEEE-SLY-DL---AASEPKKHELSDISELPEKS------DKDSTSAYNT-GESCRSTP B7NZP0_RABIT B7NZP0_RABIT LLEEE-SLY-DL---AACEPKKRELPDISELPEKS------DKDSTSAYNT-GESCRSTP B1MTU2_CALMO B1MTU2_CALMO LLEEE-SLY-DL---AASEPKKHELSDISELPEKS------DKDSTSAYNT-GESCRSTP B3KW03_HUMAN B3KW03_HUMAN LLEEE-SLY-DL---AASEPKKHELSDISELPEKS------DKDSTSTYNT-GESCRSTP B3KVR9_HUMAN B3KVR9_HUMAN LLEEE-SLY-DL---AASEPKKHELSDISELPEKS------DKDSTSAYNT-GESCRSTP B7ZKY3_HUMAN B7ZKY3_HUMAN LLEEE-SLY-DL---AASEPKKHELSDISELPEKS------DKDSTSAYNT-GESCRSTP Q17RL8_HUMAN Q17RL8_HUMAN LLEEE-SLY-DL---AASEPKKHELSDISELPEKS------DKDSTSAYNT-GESCRSTP PDZD4_HUMAN PDZD4_HUMAN LLEEE-SLY-DL---AASEPKKHELSDISELPEKS------DKDSTSAYNT-GESCRSTP MATCH * . CONSENSUS ?L??????????????????????L?DI?E?PEKS??????DKDS?SAYNT??ESCRSTP

Q4SR18_TETNG Q4SR18_TETNG LTLE--LSPDN----SLRRA-----TE-NPAPTGAPASGGG------------------- Q6DE42_XENLA Q6DE42_XENLA LTLE--ISPDN----SLRRM-----ADIINSPNAEGAVGNAAC----------------- B7Z5X9_HUMAN B7Z5X9_HUMAN LTLE--ISPDN----SLRRA-----AEGISCPSSEGAVGTTEAY---------------- B7ZAG0_HUMAN B7ZAG0_HUMAN LTLE--ISPDN----SLRRA-----AEGISCPSSEGAVGTTEA-----Y----------- B2RWP2_HUMAN B2RWP2_HUMAN LTLE--ISPDN----SLRRA-----AEGISCPSSEGAVGTTEAY---------------- PZRN3_HUMAN PZRN3_HUMAN LTLE--ISPDN----SLRRA-----AEGISCPSSEGAVGTTEAY---------------- B7ZAC9_HUMAN B7ZAC9_HUMAN LTLE--ISPDN----SLRRA-----AEGISCPSSEGAVGTTEA-----Y----------- B7Z2I8_HUMAN B7Z2I8_HUMAN LTLE--ISPDN----SLRRA-----VEGISCPSSEGAVGTTEA-----Y----------- B7Z5Q3_HUMAN B7Z5Q3_HUMAN LTLE--ISPDN----SLRRA-----VEGISCPSSEGAVGTTEA-----Y----------- PZRN3_RAT PZRN3_RAT LTLE--ISPDN----SLRRV-----AEGSS----EGATANMEAY---------------- PZRN3_MOUSE PZRN3_MOUSE LTLE--ISPDN----SLRRV-----AEGSS----EGATANIEA-----Y----------- Q3UPS8_MOUSE Q3UPS8_MOUSE LTLE--ISPDN----SLRRV-----AEGSS----EGATANIEA-----Y----------- Q4RSH1_TETNG Q4RSH1_TETNG LAMD--RSPEH----SLQRM-----VSLTNQRNLRT------------------------ Q3UXJ7_MOUSE Q3UXJ7_MOUSE LTVD--RSPDS----SLPRM-----INLTNKKNLRS------------------------ B9EKP7_MOUSE B9EKP7_MOUSE LTVD--RSPDS----SLPRM-----INLTNKKNLRS------------------------ Q69Z24_MOUSE Q69Z24_MOUSE LTVD--RSPDS----SLPRM-----INLTNKKNLRS------------------------ B4DGD1_HUMAN B4DGD1_HUMAN LTVD--RSPDS----SLPRV-----INLTNKKNLRS------------------------ PZRN4_HUMAN PZRN4_HUMAN LTVD--RSPDS----SLPRV-----INLTNKKNLRS------------------------ B4DG65_HUMAN B4DG65_HUMAN LTVD--RSPDS----SLPRV-----INLTNKKNLRS------------------------ Q4RHM6_TETNG Q4RHM6_TETNG LGVE--RSPDH----SLQRH-----ISITNQKNLTLASST-------------------- Q5TYS9_DANRE Q5TYS9_DANRE LGTE--GSPDH----SLQRR-----IHLTNQRNLRSMQSPYSSPILSLPSQSSSTCSRAH Q5BLD5_DANRE Q5BLD5_DANRE ---------------PLDRA-----VEGESE----------------------------- Q4T8B3_TETNG Q4T8B3_TETNG LVSTDHLPPEEERVLSLPLG-----SLPSISLPLTPQSHRQDRDRERRHSNLSCNFSPST B4F6T6_XENTR B4F6T6_XENTR LMMEPPLPLES----PIRRINDPSTASGAFCQPTEGHCS--------------------- A2AFG3_MOUSE A2AFG3_MOUSE LLVE--PLPES----PLKRS-----GAGNSNLNRTP------------------------ PDZD4_MOUSE PDZD4_MOUSE LLVE--PLPES----PLKRS-----GAGNSNLNRTP------------------------ B7NZP0_RABIT B7NZP0_RABIT LLAE--PLPES----PLRRA-----TAGNSNLNRTP------------------------ B1MTU2_CALMO B1MTU2_CALMO LLVE--PLPES----PLRRA-----AAGNSNLNRTP------------------------ B3KW03_HUMAN B3KW03_HUMAN LLVE--PLPES----PLRRA-----TAGNSNLNRTP------------------------ B3KVR9_HUMAN B3KVR9_HUMAN LLVE--PLPES----PLRRA-----MAGNSNLNRTP------------------------ B7ZKY3_HUMAN B7ZKY3_HUMAN LLVE--PLPES----PLRRA-----MAGNSNLNRTP------------------------ Q17RL8_HUMAN Q17RL8_HUMAN LLVE--PLPES----PLRRA-----MAGNSNLNRTP------------------------ PDZD4_HUMAN PDZD4_HUMAN LLVE--PLPES----PLRRA-----MAGNSNLNRTP------------------------ MATCH .: CONSENSUS L???????P???????L?R?????????????????????????????????????????

Q4SR18_TETNG Q4SR18_TETNG ---GSSGRMLKPLSFPLPEASGPSR-SRVSSKDPAGGLQVDSK--------DRKL-GESS Q6DE42_XENLA Q6DE42_XENLA ----SAPQKTSQSNGD-SRESSPAR-YHLPPKDTDSSQQTETK--------ERKT-SDTD B7Z5X9_HUMAN B7Z5X9_HUMAN ---GPASKNLLSITED-PEVGTPTY-SPSLKELDPNQ-PLESK--------ERRA-SDGS B7ZAG0_HUMAN B7ZAG0_HUMAN ---GPASKNLLSITED-PEVGTPTY-SPSLKELDPNQ-PLESK--------ERRA-SDGS B2RWP2_HUMAN B2RWP2_HUMAN ---GPASKNLLSITED-PEVGTPTY-SPSLKELDPNQ-PLESK--------ERRA-SDGS PZRN3_HUMAN PZRN3_HUMAN ---GPASKNLLSITED-PEVGTPTY-SPSLKELDPNQ-PLESK--------ERRA-SDGS B7ZAC9_HUMAN B7ZAC9_HUMAN ---GPASKNLLSITED-PEVGTPTY-SPSLKELDPNQ-PLESK--------ERRA-SDGS B7Z2I8_HUMAN B7Z2I8_HUMAN ---GPASKNLLSITED-PEVGTPTY-SPSLKELDPNQ-PLESK--------ERRA-SDGS B7Z5Q3_HUMAN B7Z5Q3_HUMAN ---GPASKNLLSITED-PEVGTPTY-SPSLKELDPNQ-PLESK--------ERRA-SDGS PZRN3_RAT PZRN3_RAT ---RPSPKNLLAITED-PEVSTPNY-NPGAKELDPSQ-ALEIK--------ERRV-SDGS PZRN3_MOUSE PZRN3_MOUSE ---RPSPKNLLAITED-PEVSTPSY-NPSAKELDPSQ-ALEIK--------ERRG-SDGS Q3UPS8_MOUSE Q3UPS8_MOUSE ---RPSPKNLLAITED-PEVSTPSY-NPSAKELDPSQ-ALEIK--------ERRG-SDGS Q4RSH1_TETNG Q4RSH1_TETNG -----GIAAAHSLSPS-PVPACRAA-APNKSSSPELSQTPQPE--------EESG-RN-- Q3UXJ7_MOUSE Q3UXJ7_MOUSE --------MMTAHQSP-PRQSTREY-TSTKVKATDEG-CSVES--------LEKG-LESS B9EKP7_MOUSE B9EKP7_MOUSE --------MMTAHQSP-PRQSTREY-TSTKVKATDEG-CSVES--------LEKG-LESS Q69Z24_MOUSE Q69Z24_MOUSE --------MMTAHQSP-PRQSTREY-TSTKVKATDEG-CSVES--------LEKG-LESS B4DGD1_HUMAN B4DGD1_HUMAN --------TMAATQSS-SGQSSKES-TSTKAKTTEQG-CSAES--------KEKV-LEGS PZRN4_HUMAN PZRN4_HUMAN --------TMAATQSS-SGQSSKES-TSTKAKTTEQG-CSAES--------KEKV-LEGS B4DG65_HUMAN B4DG65_HUMAN --------TMAATQSS-SGQSSKES-TSTKAKTTEQG-CSAES--------KEKV-LEGS Q4RHM6_TETNG Q4RHM6_TETNG ----SSSPIPIPKSQSTPSRSRPADPGPVISSSPDQSNPSRSESDPALPADDERC-DKKG Q5TYS9_DANRE Q5TYS9_DANRE TYTSSTPPLQTPITSP-GSQGPSQA-FSSSLEQSPSN-PSESD--------PALP-ADDE Q5BLD5_DANRE Q5BLD5_DANRE -----------------APIGGSDQ--------------------------EGHC----- Q4T8B3_TETNG Q4T8B3_TETNG YRKHEATSGNWTHGSS-STPTTPSK-FRSLNREVASP--------------SRRGVAEGC B4F6T6_XENTR B4F6T6_XENTR ----NANMNRLQAKNVTPYPGSPEP-VPSKFRSLCRE-GRHPT--------EERL-RRGT A2AFG3_MOUSE A2AFG3_MOUSE ----SGPPVTTHLKGA-PSPGSPAK-FRSLSRDPEVG-RRQHT--------EERV-RRST PDZD4_MOUSE PDZD4_MOUSE ----SGPPVTTHLKGA-PSPGSPAK-FRSLSRDPEVG-RRQHT--------EERV-RRST B7NZP0_RABIT B7NZP0_RABIT ----PGPPGPAPTKAA-PPQGSPAK-FRSLSRDAEAG-RRQHA--------DERV-RRNP B1MTU2_CALMO B1MTU2_CALMO ----PGPPVATPAKAA-PPQGSPAK-FRSLSRDPEAS-RRQHA--------EERG-RRNP B3KW03_HUMAN B3KW03_HUMAN ----PGPAVATPAKAA-PPPGSPAK-FRSLSRDPEAG-RRQHA--------EERG-RRNP B3KVR9_HUMAN B3KVR9_HUMAN ----PGPAVATPAKAA-PPPGSPAK-FRSLSRDPEAG-RRQHA--------EERG-RRNP B7ZKY3_HUMAN B7ZKY3_HUMAN ----PGPAVATPAKAA-PPPGSPAK-FRSLSRDPEAG-RRQHA--------EERG-RRNP Q17RL8_HUMAN Q17RL8_HUMAN ----PGPAVATPAKAA-PPPGSPAK-FRSLSRDPEAG-RRQHA--------EERG-RRNP PDZD4_HUMAN PDZD4_HUMAN ----PGPAVATPAKAA-PPPGSPAK-FRSLSRDPEAG-RRQHA--------EERG-RRNP MATCH CONSENSUS ????????????????????????????????????????????????????????????

Q4SR18_TETNG Q4SR18_TETNG KSGRS-------------FPQPHSPYKHAHIPAHAQHYQSYMQL---------IQQK--S Q6DE42_XENLA Q6DE42_XENLA KNHIS--QDKVSG--SYAPPYRHSPYKHAHIPAHAQHYQSYMQL---------IQQK--S B7Z5X9_HUMAN B7Z5X9_HUMAN RSPTP--SQKLGS--AYLPSYHHSPYKHAHIPAHAQHYQSYMQL---------IQQK--S B7ZAG0_HUMAN B7ZAG0_HUMAN RSPTP--SQKLGS--AYLPSYHHSPYKHAHIPAHAQHYQSYMQL---------IQQK--S B2RWP2_HUMAN B2RWP2_HUMAN RSPTP--SQKLGS--AYLPSYHHSPYKHAHIPAHAQHYQSYMQL---------IQQK--S PZRN3_HUMAN PZRN3_HUMAN RSPTP--SQKLGS--AYLPSYHHSPYKHAHIPAHAQHYQSYMQL---------IQQK--S B7ZAC9_HUMAN B7ZAC9_HUMAN RSPTP--SQKLGS--AYLPSYHHSPYKHAHIPAHAQHYQSYMQL---------IQQK--S B7Z2I8_HUMAN B7Z2I8_HUMAN RSPTP--SQKLGS--AYLPSYHHSPYKHAHIPAHAQHYQSYMQL---------IQQK--S B7Z5Q3_HUMAN B7Z5Q3_HUMAN RSPTP--SQKLGS--AYLPSYHHSPYKHAHIPAHAQHYQSYMQL---------IQQK--S PZRN3_RAT PZRN3_RAT RSPTA--SPKLGS--AYLPSYHHSPYKHAHIPAHAQHYQSYMHL---------IQQK--S PZRN3_MOUSE PZRN3_MOUSE RSPTA--SPKLGN--AYLPSYHHSPYKHAHIPAHAQHYQSYMHL---------IQQK--S Q3UPS8_MOUSE Q3UPS8_MOUSE RSPTA--SPKLGN--AYLPSYHHSPYKHAHIPAHAQHYQSYMHL---------IQQK--S Q4RSH1_TETNG Q4RSH1_TETNG -------LKSYASPNPYFSPSHSSQQRQ-------------------------EPQR--- Q3UXJ7_MOUSE Q3UXJ7_MOUSE QLLDQ--EHTVSEHPPYLSPYHSSSYRYANIPAHARHYQSYMQL---------IQQK--S B9EKP7_MOUSE B9EKP7_MOUSE QLLDQ--EHTVSEHPPYLSPYHSSSYRYANIPAHARHYQSYMQL---------IQQK--S Q69Z24_MOUSE Q69Z24_MOUSE QLLDQ--EHTVSEHPPYLSPYHSSSYRYANIPAHARHYQSYMQL---------IQQK--S B4DGD1_HUMAN B4DGD1_HUMAN KLPDQ--EKAVSEHIPYLSPYHSSSYRYANIPAHARHYQSYMQL---------IQQK--S PZRN4_HUMAN PZRN4_HUMAN KLPDQ--EKAVSEHIPYLSPYHSSSYRYANIPAHARHYQSYMQL---------IQQK--S B4DG65_HUMAN B4DG65_HUMAN KLPDQ--EKAVSEHTPYLSPYHSSSYRYANIPAHARHYQSYMQL---------IQQK--S Q4RHM6_TETNG Q4RHM6_TETNG RTRES--RRGL----PYASSYLTSPYQSQG---GSRQLQSYMQL---------LQQH--S Q5TYS9_DANRE Q5TYS9_DANRE RCEKERNRNRLAAARQYHSPYHTSTTT--TQPPSTRHYQSYLQL---------LQQHSSS Q5BLD5_DANRE Q5BLD5_DANRE -------EKTLGS----------------------------------------LPHP--S Q4T8B3_TETNG Q4T8B3_TETNG RAGGA--TNRPGGVSAESSPYLSR--RRHNHHQAQERYQSCMTLPSDGLVEHLEQVRDRV B4F6T6_XENTR B4F6T6_XENTR KPVTE--LDRGS---RESSPYLGR----RQRSQSGERYRSCLQL---------AQPR--S A2AFG3_MOUSE A2AFG3_MOUSE KTSVT--LERVG---PEGSPYLSR----RHRGQEIEQYHSCVQL---------APPR--T PDZD4_MOUSE PDZD4_MOUSE KTSVT--LERVG---PEGSPYLSR----RHRGQEIEQYHSCVQL---------APPR--T B7NZP0_RABIT B7NZP0_RABIT KMGVT--LERVG---PEGSPYLSR--RHRGQGQESEQYHSCVQL---------APTR--G B1MTU2_CALMO B1MTU2_CALMO KTGLA--LERMG---PEGSPYLSR--RHRGQGQEGEHYHSCMQL---------APTR--G B3KW03_HUMAN B3KW03_HUMAN KTGLT--LERVG---PESSPYLSR--RHRGQGQEGEHYHSCVQL---------APTR--G B3KVR9_HUMAN B3KVR9_HUMAN KTGLT--LERVG---PESSPYLSR--RHRGQGQEGEHYHSCVQL---------APTR--G B7ZKY3_HUMAN B7ZKY3_HUMAN KTGLT--LERVG---PESSPYLSR--RHRGQGQEGEHYHSCVQL---------APTR--G Q17RL8_HUMAN Q17RL8_HUMAN KTGLT--LERVG---PESSPYLSR--RHRGQGQEGEHYHSCVQL---------APTR--G PDZD4_HUMAN PDZD4_HUMAN KTGLT--LERVG---PESSPYLSR--RHRGQGQEGEHYHSCVQL---------APTR--G MATCH CONSENSUS ????????????????????Y????????????????Y?S??QL????????????????

Q4SR18_TETNG Q4SR18_TETNG AVEYA---------------------------QSQMSLVSMCRDP---VSPTDLEP-KME Q6DE42_XENLA Q6DE42_XENLA AVEYA---------------------------QSQMSLVSMCKDL-----SNSMEP-RME B7Z5X9_HUMAN B7Z5X9_HUMAN AVEYA---------------------------QSQMSLVSMCKDL---SSPTPSEP-RME B7ZAG0_HUMAN B7ZAG0_HUMAN AVEYA---------------------------QSQMSLVSMCKDL---SSPTPSEP-RME B2RWP2_HUMAN B2RWP2_HUMAN AVEYA---------------------------QSQMSLVSMCKDL---SSPTPSEP-RME PZRN3_HUMAN PZRN3_HUMAN AVEYA---------------------------QSQMSLVSMCKDL---SSPTPSEP-RME B7ZAC9_HUMAN B7ZAC9_HUMAN AVEYA---------------------------QSQMSLVSMCKDL---SSPTPSEP-RME B7Z2I8_HUMAN B7Z2I8_HUMAN AVEYA---------------------------QSQMSLVSMCKDL---SSPTPSEP-RME B7Z5Q3_HUMAN B7Z5Q3_HUMAN AVEYA---------------------------QSQMSLVSMCKDL---SSPTPSEP-RME PZRN3_RAT PZRN3_RAT AVEYA---------------------------QSQMSLVSMCKDL---NSSNSAEP-RME PZRN3_MOUSE PZRN3_MOUSE AVEYA---------------------------QSQMSLVSMCKDL---NSSNSVEP-RME Q3UPS8_MOUSE Q3UPS8_MOUSE AVEYA---------------------------QSQMSLVSMCKDL---NSSNSVEP-RME Q4RSH1_TETNG Q4RSH1_TETNG ---------------------------------------------------PVSEP-KME Q3UXJ7_MOUSE Q3UXJ7_MOUSE AVEYA---------------------------QSQLSLVSMCK-----ESQRGSEP-KME B9EKP7_MOUSE B9EKP7_MOUSE AVEYA---------------------------QSQLSLVSMCK-----ESQRGSEP-KME Q69Z24_MOUSE Q69Z24_MOUSE AVEYA---------------------------QSQLSLVSMCK-----ESQRGSEP-KME B4DGD1_HUMAN B4DGD1_HUMAN AVEYA---------------------------QSQLSLVSMCK-----ESQKCSEP-KME PZRN4_HUMAN PZRN4_HUMAN AVEYA---------------------------QSQLSLVSMCK-----ESQKCSEP-KME B4DG65_HUMAN B4DG65_HUMAN AVEYA---------------------------QSQLSLVSMCK-----ESQKCSEP-KME Q4RHM6_TETNG Q4RHM6_TETNG SLEYS---------------------------QSQLSLLSLCRDQVQQSGR-PGEP-HLE Q5TYS9_DANRE Q5TYS9_DANRE SLEYS---------------------------QSQLSLLSLR------GRPGPSQAGRLE Q5BLD5_DANRE Q5BLD5_DANRE PVKLS--------------------------LALPLPLS-------------PASP-RME Q4T8B3_TETNG Q4T8B3_TETNG RVEVGERAVATGSSGPASPRSINSAPCGLEDHQVSVPHLGLALPLGMAHSSPTASPQRME B4F6T6_XENTR B4F6T6_XENTR LDELD---------------------------ADP---TCGKSIGASPGTQSQAEP-RME A2AFG3_MOUSE A2AFG3_MOUSE LEDLG---------------------------HGSLSLASGPRVGGV-AAAAVEAP-RME PDZD4_MOUSE PDZD4_MOUSE LEDLG---------------------------HGSLSLASGPRVGGV-AAAAVEAP-RME B7NZP0_RABIT B7NZP0_RABIT LEELG---------------------------HSSLGLAGGPRVGGV-AAAAPEAP-RME B1MTU2_CALMO B1MTU2_CALMO LEELG---------------------------HGPLSLAGGPRVGGG-AAAATEAP-RME B3KW03_HUMAN B3KW03_HUMAN LEELG---------------------------HGPLSLAGGPRVGGV-AAAATEAP-RME B3KVR9_HUMAN B3KVR9_HUMAN LEELG---------------------------HGPLSLAGGPRVGGV-AAAATEAP-RME B7ZKY3_HUMAN B7ZKY3_HUMAN LEELG---------------------------HGPLSLAGGPRVGGV-AAAATEAP-RME Q17RL8_HUMAN Q17RL8_HUMAN LEELG---------------------------HGPLSLAGGPRVGGV-AAAATEAP-RME PDZD4_HUMAN PDZD4_HUMAN LEELG---------------------------HGPLSLAGGPRVGGV-AAAATEAP-RME MATCH . ::* CONSENSUS ??E?????????????????????????????????SL?????????????????P??ME

Q4SR18_TETNG Q4SR18_TETNG WKVKIRSDGTRYITKRPIRDKLLRERALRIHEE-RSGMTTDDDALSELKMGRYWSKEERK Q6DE42_XENLA Q6DE42_XENLA WKVKVRSDGSRYITKRPVRDKLLKERAIKIKEE-RSGMTTDDDAISEMKMGRYWSKEERK B7Z5X9_HUMAN B7Z5X9_HUMAN WKVKIRSDGTRYITKRPVRDRLLRERALKIREE-RSGMTTDDDAVSEMKMGRYWSKEERK B7ZAG0_HUMAN B7ZAG0_HUMAN WKVKIRSDGTRYITKRPVRDRLLRERALKIREE-RSGMTTDDDAVSEMKMGRYWSKEERK B2RWP2_HUMAN B2RWP2_HUMAN WKVKIRSDGTRYITKRPVRDRLLRERALKIREE-RSGMTTDDDAVSEMKMGRYWSKEERK PZRN3_HUMAN PZRN3_HUMAN WKVKIRSDGTRYITKRPVRDRLLRERALKIREE-RSGMTTDDDAVSEMKMGRYWSKEERK B7ZAC9_HUMAN B7ZAC9_HUMAN WKVKIRSDGTRYITKRPVRDRLLRERALKIREE-RSGMTTDDDAVSEMKMGRYWSKEERK B7Z2I8_HUMAN B7Z2I8_HUMAN WKVKIRSDGTRYITKRPVRDRLLRERALKIREE-RSGMTTDDDAVSEMKMGRYWSKEERK B7Z5Q3_HUMAN B7Z5Q3_HUMAN WKVKIRSDGTRYITKRPVRDRLLRERALKIREE-RSGMTTDDDAVSEMKMGRYWSKEERK PZRN3_RAT PZRN3_RAT WKVKIRSDGTRYITKRPVRDRLLRERALKIREE-RSGLTTDDDAMSEMKMGRYWSKEERK PZRN3_MOUSE PZRN3_MOUSE WKVKIRSDGTRYITKRPVRDRLLRERALKIREE-RSGLTTDDDAMSEMKMGRYWSKEERK Q3UPS8_MOUSE Q3UPS8_MOUSE WKVKIRSDGTRYITKRPVRDRLLRERALKIREE-RSGLTTDDDAMSEMKMGRYWSKEERK Q4RSH1_TETNG Q4RSH1_TETNG WKVKIRSDGTRYITKRPVRDKILRERALKIKEERRTGMTTDDDAMSEMKMGRYWSKEERK Q3UXJ7_MOUSE Q3UXJ7_MOUSE WKVKIRSDGTRYITKRPVRDRLLKERALKIKEE-RSGMTTDDDTMSEMKMGRYWSKEERK B9EKP7_MOUSE B9EKP7_MOUSE WKVKIRSDGTRYITKRPVRDRLLKERALKIKEE-RSGMTTDDDTMSEMKMGRYWSKEERK Q69Z24_MOUSE Q69Z24_MOUSE WKVKIRSDGTRYITKRPVRDRLLKERALKIKEE-RSGMTTDDDTMSEMKMGRYWSKEERK B4DGD1_HUMAN B4DGD1_HUMAN WKVKIRSDGTRYITKRPVRDRILKERALKIKEE-RSGMTTDDDTMSEMKMGRYWSKEERK PZRN4_HUMAN PZRN4_HUMAN WKVKIRSDGTRYITKRPVRDRILKERALKIKEE-RSGMTTDDDTMSEMKMGRYWSKEERK B4DG65_HUMAN B4DG65_HUMAN WKVKIRSDGTRYITKRPVRDRILKERALKIKEE-RSGMTTDDDTMSEMKMGRYWSKEERK Q4RHM6_TETNG Q4RHM6_TETNG WKVKVRADGTRYVARRPARDRILRERALRIREERSGGMTTDDDAMSEMKMGRYWSKEERK Q5TYS9_DANRE Q5TYS9_DANRE WKVKVRADGTRYVARRPARDRILRERALRIREERSGGMTTDDDAVSELKMGRYWSKEERK Q5BLD5_DANRE Q5BLD5_DANRE WKVKIRSDGTRYVAKRPVRDRLLKARAMKIREE-RSGMTTDDDAVSEMKMGRYWSKEERK Q4T8B3_TETNG Q4T8B3_TETNG WKVKIRSDGTRYVTKRPVRDRLLKARAMKIKEE-RSGMTTDDDAASEMKQGRYWSKEERK B4F6T6_XENTR B4F6T6_XENTR WKVKIRSDGTRYVTKRPVRDRLLKARAMKIKEE-RSGMTTDDDAVSEMKMGRYWSKEDRK A2AFG3_MOUSE A2AFG3_MOUSE WKVKVRSDGTRYVAKRPVRDRLLKARALKIREE-RSGMTTDDDAVSEMKMGRYWSKEERK PDZD4_MOUSE PDZD4_MOUSE WKVKVRSDGTRYVAKRPVRDRLLKARALKIREE-RSGMTTDDDAVSEMKMGRYWSKEERK B7NZP0_RABIT B7NZP0_RABIT WKVKVRSDGTRYVAKRPVRDRLLKARALKIREE-RSGMTTDDDAVSEMKMGRYWSKEERK B1MTU2_CALMO B1MTU2_CALMO WKVKVRSDGTRYVAKRPVRDRLLKARALKIREE-RSGMTTDDDAVSEMKMGRYWSKEERK B3KW03_HUMAN B3KW03_HUMAN WKVKVRSDGTRYVAKRPVRDRLLKARALKIREE-RSGMTTDDDAVSEMKMGRYWSKEERK B3KVR9_HUMAN B3KVR9_HUMAN WKVKVRSDGTRYVAKRPVRDRLLKARALKIREE-RSGMTTDDDAVSEMKMGRYWSKEERK B7ZKY3_HUMAN B7ZKY3_HUMAN WKVKVRSDGTRYVAKRPVRDRLLKARALKIREE-RSGMTTDDDAVSEMKMGRYWSKEERK Q17RL8_HUMAN Q17RL8_HUMAN WKVKVRSDGTRYVAKRPVRDRLLKARALKIREE-RSGMTTDDDAVSEMKMGRYWSKEERK PDZD4_HUMAN PDZD4_HUMAN WKVKVRSDGTRYVAKRPVRDRLLKARALKIREE-RSGMTTDDDAVSEMKMGRYWSKEERK MATCH ****:*:**:**:::** **::*: **::*:** *:*****: **:* *******:** CONSENSUS WKVK?RSDGTRY??KRPVRDRLL??RALKI?EE?RSGMTTDDDA?SEMKMGRYWSKEERK

Q4SR18_TETNG Q4SR18_TETNG QHAVRAKEQRQRREFMKQSRADCLKE--------QSSAEDKKEPN----IIELSHKKMMK Q6DE42_XENLA Q6DE42_XENLA QHVRRANEQKRRREYMMQSRLDCLKE--------KQSTEDNKEVS----IIDLSHKKMMK B7Z5X9_HUMAN B7Z5X9_HUMAN QHLVKAKEQRRRREFMMQSRLDCLKE--------QQAADDRKEMN----ILELSHKKMMK B7ZAG0_HUMAN B7ZAG0_HUMAN QHLVKAKEQRRRREFMMQSRLDCLKE--------QQAADDRKEMN----ILELSHKKMMK B2RWP2_HUMAN B2RWP2_HUMAN QHLVKAKEQRRRREFMMQSRLDCLKE--------QQAADDRKEMN----ILELSHKKMMK PZRN3_HUMAN PZRN3_HUMAN QHLVKAKEQRRRREFMMQSRLDCLKE--------QQAADDRKEMN----ILELSHKKMMK B7ZAC9_HUMAN B7ZAC9_HUMAN QHLVKAKEQRRRREFMMQSRLDCLKE--------QQAADDRKEMN----ILELSHKKMMK B7Z2I8_HUMAN B7Z2I8_HUMAN QHLVKAKEQRRRREFMMQSRLDCLKE--------QQAADDRKEMN----ILELSHKKMMK B7Z5Q3_HUMAN B7Z5Q3_HUMAN QHLVKAKEQRRRREFMMQSRLDCLKE--------QQAADDRKEMN----ILELSHKKMMK PZRN3_RAT PZRN3_RAT QHLVKAKEQRRRREFMMQSRLDCLKE--------QQASDDRKEMN----ILELSHKKMMK PZRN3_MOUSE PZRN3_MOUSE QHLVKAKEQRRRREFMMQSRLDCLKE--------QQASDDRKEMN----ILELSHKKMMK Q3UPS8_MOUSE Q3UPS8_MOUSE QHLVKAKEQRRRREFMMQSRLDCLKE--------QQASDDRKEMN----ILELSHKKMT- Q4RSH1_TETNG Q4RSH1_TETNG QHLVRAKEQRKRREFMQRSRLESLRE------NPQSSSESRREVS----IIELSHKKMMK Q3UXJ7_MOUSE Q3UXJ7_MOUSE QHLVRAKEQRRRREFMMRSRLESLKE------SPQSSGEGKKELS----IIELSHKKMT- B9EKP7_MOUSE B9EKP7_MOUSE QHLVRAKEQRRRREFMMRSRLESLKE------SPQSSGEGKKELS----IIELSHKKMMK Q69Z24_MOUSE Q69Z24_MOUSE QHLVRAKEQRRRREFMMRSRLESLKE------SPQSSGEGKKELS----IIELSHKKMMK B4DGD1_HUMAN B4DGD1_HUMAN QHLVRAKEQRRRREFMMRSRLECLKE------SPQSGSEGKKEIN----IIELSHKKMMK PZRN4_HUMAN PZRN4_HUMAN QHLVRAKEQRRRREFMMRSRLECLKE------SPQSGSEGKKEIN----IIELSHKKMMK B4DG65_HUMAN B4DG65_HUMAN QHLVRAKEQRRRREFMMRSRLECLKE------SPQSGSEGKKEIN----IIELSHKKMMK Q4RHM6_TETNG Q4RHM6_TETNG QHLARAREQRKRREFMQKSRLDCLRE------GPGSGVEGRKEIN----ILELSHKKMLK Q5TYS9_DANRE Q5TYS9_DANRE QQLARAREQRRRREFMQKSRLECLRE---------TMGTASGEVS----ILELSHKKMLK Q5BLD5_DANRE Q5BLD5_DANRE QQLLKAREQRRRREFMIQSRLDYLRDHGLDVGKDSQSESGQNSAS----ILELSQKKSSK Q4T8B3_TETNG Q4T8B3_TETNG QQLLRAREHRRRRELMMQSRLDYLRG--DRDSSSPPGGCDHPQPHSGSTILSLSQRKTTK B4F6T6_XENTR B4F6T6_XENTR RHLMRAREQRKRREFMMQSRLDCLRE---QQQQQQQGLEGKGEMS----IIALSHRKTMK A2AFG3_MOUSE A2AFG3_MOUSE QHLIRAREQRKRREFMMQSRLECLRE--------QQNGDSKPELN----IIALSHRKTMK PDZD4_MOUSE PDZD4_MOUSE QHLIRAREQRKRREFMMQSRLECLRE--------QQNGDSKPELN----IIALSHRKTMK B7NZP0_RABIT B7NZP0_RABIT QHLIRAREQRKRREFMMQSRLECLRE---------QSGDGKTELN----IIALSHRKTMK B1MTU2_CALMO B1MTU2_CALMO QHLIRAREQRKRREFMMQSRLECLRE--------QQNGDSKPELN----IIALSHRKTMK B3KW03_HUMAN B3KW03_HUMAN QHLIRAREQRKRREFMMQSRLECLRE--------QQNGDSKPELN----IIALSHRKTMK B3KVR9_HUMAN B3KVR9_HUMAN QHLIRAREQRKRREFMMQSRLECLRE--------QQNGDSKPELN----IIALSHRKTMK B7ZKY3_HUMAN B7ZKY3_HUMAN QHLIRAREQRKRREFMMQSRLECLRE--------QQNGDSKPELN----IIALSHRKTMK Q17RL8_HUMAN Q17RL8_HUMAN QHLIRAREQRKRREFMMQSRLECLRE--------QQNGDSKPELN----IIALSHRKTMK PDZD4_HUMAN PDZD4_HUMAN QHLIRAREQRKRREFMMQSRLECLRE--------QQNGDSKPELN----IIALSHRKTMK MATCH :: :*.*:::*** * :** : *: . *: **::* CONSENSUS QHL??A?EQR?RREFMM?SRL?CL?E????????Q???????E??????I??LSH?K?MK

Q4SR18_TETNG Q4SR18_TETNG KRSKKIFDNWMTIQELLTHGTKSPEGTRVYNSLLSVTTV Q6DE42_XENLA Q6DE42_XENLA KRNKKVFDNWMTIQELLTHGTKSPDGTRVYNSLLSVTTV B7Z5X9_HUMAN B7Z5X9_HUMAN KRNKKIFDNWMTIQELLTHGTKSPDGTRVYNSFLSVTTV B7ZAG0_HUMAN B7ZAG0_HUMAN KRNKKIFDNWMTIQELLTHGTKSPDGTRVYNSFLSVTTV B2RWP2_HUMAN B2RWP2_HUMAN KRNKKIFDNWMTIQELLTHGTKSPDGTRVYNSFLSVTTV PZRN3_HUMAN PZRN3_HUMAN KRNKKIFDNWMTIQELLTHGTKSPDGTRVYNSFLSVTTV B7ZAC9_HUMAN B7ZAC9_HUMAN KRNKKIFDNWMTIQELLTHGTKSPDGTRVYNSFLSVTTV B7Z2I8_HUMAN B7Z2I8_HUMAN KRNKKIFDNWMTIQELLTHGTKSPDGTRVYNSFLSVTTV B7Z5Q3_HUMAN B7Z5Q3_HUMAN KRNKKIFDNWMTIQELLTHGTKSPDGTRVYNSFLSVTTV PZRN3_RAT PZRN3_RAT KRNKKIFDNWMTIQELLTHGTKSPDGTRVYNSFLSVTTV PZRN3_MOUSE PZRN3_MOUSE KRNKKIFDNWMTIQELLTHGTKSPDGTRVYNSFLSVTTV Q3UPS8_MOUSE Q3UPS8_MOUSE --------------------------------------- Q4RSH1_TETNG Q4RSH1_TETNG KRNKKILDNWMTIQELMTHGAKAPEGAKVHNAFLSVTTV Q3UXJ7_MOUSE Q3UXJ7_MOUSE --------------------------------------- B9EKP7_MOUSE B9EKP7_MOUSE KRNKKILDNWMTIQELMTHGAKSPDGTRVHNAFLSVTTV Q69Z24_MOUSE Q69Z24_MOUSE KRNKKILDNWMTIQELMTHGAKSPDGTRVHNAFLSVTTV B4DGD1_HUMAN B4DGD1_HUMAN KRNKKILDNWMTIQELMTHGAKSPDGTRVHNAFLSVTTV PZRN4_HUMAN PZRN4_HUMAN KRNKKILDNWMTIQELMTHGAKSPDGTRVHNAFLSVTTV B4DG65_HUMAN B4DG65_HUMAN KRNKKILDNWMTIQELMTHGAKSPDGTRVHNAFLSVTTV Q4RHM6_TETNG Q4RHM6_TETNG KRNKKILDNWMTIQELMSHGARVPEDSKVHNAFLSVTTV Q5TYS9_DANRE Q5TYS9_DANRE KRNKKILDNWMTIQELMSHGARAPEGTKVHNAFLSVTTV Q5BLD5_DANRE Q5BLD5_DANRE KRNRRILDNWITIQELLAHGSRSPDGTKVYNPLLSVTTV Q4T8B3_TETNG Q4T8B3_TETNG KRNRRILDNWITIQELLAHGSKSPDGKKIFNPLLSVTTV B4F6T6_XENTR B4F6T6_XENTR KRNKKILDNWITIQEMLAHGTRSADGKRVYNPLLSVTTV A2AFG3_MOUSE A2AFG3_MOUSE KRNKKILDNWITIQEMLAHGARSADGKRIYNPLLSVTTV PDZD4_MOUSE PDZD4_MOUSE KRNKKILDNWITIQEMLAHGARSADGKRIYNPLLSVTTV B7NZP0_RABIT B7NZP0_RABIT KRNKKILDNWITIQEMLAHGARSADGKRVYNPLLSVTTV B1MTU2_CALMO B1MTU2_CALMO KRNKKILDNWITIQEMLAHGARSADGKRVYNPLLSVTTV B3KW03_HUMAN B3KW03_HUMAN KRNKKILDNWITIQEMLAHGARSADGKRVYNPLLSVTTV B3KVR9_HUMAN B3KVR9_HUMAN KRNKKILDNWITIQEMLAHGARSADGKRVYNPLLSVTTV B7ZKY3_HUMAN B7ZKY3_HUMAN KRNKKILDNWITIQEMLAHGARSADGKRVYNPLLSVTTV Q17RL8_HUMAN Q17RL8_HUMAN KRNKKILDNWITIQEMLAHGARSADGKRVYNPLLSVTTV PDZD4_HUMAN PDZD4_HUMAN KRNKKILDNWITIQEMLAHGARSADGKRVYNPLLSVTTV MATCH CONSENSUS KRNKKI?DNW?TIQE???HG??S?DG??V?N??LSVTTV


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