Alignment of the gene Family HBG056372 of HOVERGEN

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Threshold: 50% 80% 100%
Size: Bigger Smaller Normal
Isoforms are ON
Q5VSI7_DANRE Q5VSI7_DANRE -----------------------MESLTLSDVEQKYYSELFLSCD--------------- Q28CL0_XENTR Q28CL0_XENTR ------------------------------------------------------------ Q5GMN1_XENLA Q5GMN1_XENLA ------------------------------------------------------------ Q4S761_TETNG Q4S761_TETNG ------------------------------------------------------------ Q5ZK42_CHICK Q5ZK42_CHICK -----------------------MEGLTLSEAEQRYYCDLFSYCD--------------- REPS1_MOUSE REPS1_MOUSE -----------------------MEGLTLSDAEQKYYSDLFSYCD--------------- A3KMX4_BOVIN A3KMX4_BOVIN ---------------------------------QKYYSDLFSYCD--------------- Q59GG6_HUMAN Q59GG6_HUMAN ------------------------------------------------------------ B2R7D3_HUMAN B2R7D3_HUMAN ------------------------------------------------------------ B7ZBZ8_HUMAN B7ZBZ8_HUMAN -----------------------MEGLTLSDAEQKYYSDLFSYCD--------------- REPS1_HUMAN REPS1_HUMAN -----------------------MEGLTLSDAEQKYYSDLFSYCD--------------- B7ZC00_HUMAN B7ZC00_HUMAN -----------------------MEGLTLSDAEQKYYSDLFSYCD--------------- B7ZBZ9_HUMAN B7ZBZ9_HUMAN -----------------------MEGLTLSDAEQKYYSDLFSYCD--------------- Q5JWJ8_HUMAN Q5JWJ8_HUMAN ------------------------------------------------------------ Q4SZC7_TETNG Q4SZC7_TETNG ------------------------------------------------------------ Q5ZII0_CHICK Q5ZII0_CHICK -------MEQGPAGGPAAAVAAAGVLVPLSESEQQRYSELFSRC---------------- Q3UHE9_MOUSE Q3UHE9_MOUSE ------------------------------------------------------------ B1AV20_MOUSE B1AV20_MOUSE ------------------------------------------------------------ Q3UHF8_MOUSE Q3UHF8_MOUSE ------------------------------------------------------------ REPS2_MOUSE REPS2_MOUSE ------------------------------------------------------------ A2AFI8_MOUSE A2AFI8_MOUSE ------------MEVAAGGGCGAGPPLLLSDSEQQCYSELFARCAGAASGGPGPGPPEAT B9EI38_MOUSE B9EI38_MOUSE ------------MEVAAGGGCGAGPPLLLSDSEQQCYSELFARCAGAASGGPGPGPPEAT Q59H22_HUMAN Q59H22_HUMAN ------------------------------------------------------------ B4DQQ8_HUMAN B4DQQ8_HUMAN ------------------------------------------------------------ A6PWZ6_HUMAN A6PWZ6_HUMAN EAAAAAAAAAAAAAAAGGGCGSGPPPLLLSEGEQQCYSELFARCAGAAGGGPGSGPPEAA REPS2_HUMAN REPS2_HUMAN EAAAAAAAAAAAAAAAGGGCGSGPPPLLLSEGEQQCYSELFARCAGAAGGGPGSGPPEAA Q5JNZ8_HUMAN Q5JNZ8_HUMAN EAAAAAAAAAAAAAAAGGGCGSGPPPLLLSEGEQQCYSELFARCAGAAGGGPGSGPPEAA MATCH CONSENSUS ????????????????????????????????????????????????????????????

Q5VSI7_DANRE Q5VSI7_DANRE -VDNAKKVASNGKVLELFRAAQLSNEVVLQITELCGATRLGHFGRSQFYIALKLIALAQS Q28CL0_XENTR Q28CL0_XENTR ------------------------------------------------------------ Q5GMN1_XENLA Q5GMN1_XENLA ------------------------------------------------------------ Q4S761_TETNG Q4S761_TETNG ------------------------------------------------------------ Q5ZK42_CHICK Q5ZK42_CHICK -TESTKKVASNGRVLELFRAAQLPNDVVMQIMELCGATRLGYFGRSQFYIALKLVAVAQS REPS1_MOUSE REPS1_MOUSE -IESTKKVVVNGRVLELFRAAQLPNDVVLQIMELCGATRLGYFGRSQFYIALKLVAVAQS A3KMX4_BOVIN A3KMX4_BOVIN -IESTKKVSANGRVLELFRAAQLPNDVVLQIMELCGATRLGYFGRSQFYIALKLVAVAQS Q59GG6_HUMAN Q59GG6_HUMAN ------------------------------------------------------------ B2R7D3_HUMAN B2R7D3_HUMAN -------------------------------MELCGATRLGYFGRSQFYIALKLVAVAQS B7ZBZ8_HUMAN B7ZBZ8_HUMAN -IESTKKVVVNGRVLELFRAAQLPNDVVLQIMELCGATRLGYFGRSQFYIALKLVAVAQS REPS1_HUMAN REPS1_HUMAN -IESTKKVVVNGRVLELFRAAQLPNDVVLQIMELCGATRLGYFGRSQFYIALKLVAVAQS B7ZC00_HUMAN B7ZC00_HUMAN -IESTKKVVVNGRVLELFRAAQLPNDVVLQIMELCGATRLGYFGRSQFYIALKLVAVAQS B7ZBZ9_HUMAN B7ZBZ9_HUMAN -IESTKKVVVNGRVLELFRAAQLPNDVVLQIMELCGATRLGYFGRSQFYIALKLVAVAQS Q5JWJ8_HUMAN Q5JWJ8_HUMAN ------------------------------------------------------------ Q4SZC7_TETNG Q4SZC7_TETNG -----------------------------QVTEVCGAKHLGYFGSPQFYVALKLLAAAQS Q5ZII0_CHICK Q5ZII0_CHICK -CPRPEAAAGGSSVGELFRASQLPPDTLHQITEVCGAKRVGYFGPAQFYIALKLIAAAQS Q3UHE9_MOUSE Q3UHE9_MOUSE ------------------------------------------------------------ B1AV20_MOUSE B1AV20_MOUSE -------------------WRERPLNHCIHITELCGAKRVGYFGPTQFYVALKLIAAAQA Q3UHF8_MOUSE Q3UHF8_MOUSE ------------------------------------------------------------ REPS2_MOUSE REPS2_MOUSE ------------------------------------------------------------ A2AFI8_MOUSE A2AFI8_MOUSE RVAPGTATAAAGPVADLFRASQLPPETLHQITELCGAKRVGYFGPTQFYVALKLIAAAQA B9EI38_MOUSE B9EI38_MOUSE RVAPGTATAAAGPVADLFRASQLPPETLHQITELCGAKRVGYFGPTQFYVALKLIAAAQA Q59H22_HUMAN Q59H22_HUMAN --------------------------------ELCGAKRVGYFGPTQFYIALKLIAAAQS B4DQQ8_HUMAN B4DQQ8_HUMAN ------------------------------------------------------------ A6PWZ6_HUMAN A6PWZ6_HUMAN RVAPGTATAAAGPVADLFRASQLPAETLHQITELCGAKRVGYFGPTQFYIALKLIAAAQS REPS2_HUMAN REPS2_HUMAN RVAPGTATAAAGPVADLFRASQLPAETLHQITELCGAKRVGYFGPTQFYIALKLIAAAQS Q5JNZ8_HUMAN Q5JNZ8_HUMAN RVAPGTATAAAGPVADLFRASQLPAETLHQITELCGAKRVGYFGPTQFYIALKLIAAAQS MATCH CONSENSUS ????????????????????????????????????????????????????????????

Q5VSI7_DANRE Q5VSI7_DANRE GLPLRLESLNTVRDLPLPRFVMGKNEQETRHMVMFT-DAENQGPF-------LPRPPGRV Q28CL0_XENTR Q28CL0_XENTR ------------------------------------------------------------ Q5GMN1_XENLA Q5GMN1_XENLA ------------------------------------------------------------ Q4S761_TETNG Q4S761_TETNG -----------VKDLPLPRFVVGKNEAEARHAALYP-DTDAQGLYPSSGPAVIPRPPGRG Q5ZK42_CHICK Q5ZK42_CHICK GLPLRVESLNTVKDLPLPRFVVSKNEQESRHAALYSSDADNPASY----SGVIPPPPGRI REPS1_MOUSE REPS1_MOUSE GFPLRVESINTVKDLPLPRFVASKNEQESRLAASYSSDSENQGSY----SGVIPPPPGRG A3KMX4_BOVIN A3KMX4_BOVIN GFPLRVESINTVKDLPLPRFVASKNEQESRHPTSYSSDSENQGSY----SGVIPPPPGRG Q59GG6_HUMAN Q59GG6_HUMAN ------------------------------------------------------------ B2R7D3_HUMAN B2R7D3_HUMAN GFPLRVESINTVKDLPLPRFVASKNEQESRHAASYSSDSENQGSY----SGVIPPPPGRG B7ZBZ8_HUMAN B7ZBZ8_HUMAN GFPLRVESINTVKDLPLPRFVASKNEQESRHAASYSSDSENQGSY----SGVIPPPPGRG REPS1_HUMAN REPS1_HUMAN GFPLRVESINTVKDLPLPRFVASKNEQESRHAASYSSDSENQGSY----SGVIPPPPGRG B7ZC00_HUMAN B7ZC00_HUMAN GFPLRVESINTVKDLPLPRFVASKNEQESRHAASYSSDSENQGSY----SGVIPPPPGRG B7ZBZ9_HUMAN B7ZBZ9_HUMAN GFPLRVESINTVKDLPLPRFVASKNEQESRHAASYSSDSENQGSY----SGVIPPPPGRG Q5JWJ8_HUMAN Q5JWJ8_HUMAN ------------------------------------------------------------ Q4SZC7_TETNG Q4SZC7_TETNG GLPIHLESLTA--NLPLPRFVGLKGDSEARFSSG---PAGGDGQLAACGTSSVSWTPA-- Q5ZII0_CHICK Q5ZII0_CHICK GFPVRIESIKN--ELPLPRFMALKDDSEVRYGT----PAELHGV-----KFQAPHATL-- Q3UHE9_MOUSE Q3UHE9_MOUSE ------------------------------------------------------------ B1AV20_MOUSE B1AV20_MOUSE GLPVRTESIKC--ELPLPRFVMSKNDGEIRFGN----PAELHGP-----KVQIPYLTT-- Q3UHF8_MOUSE Q3UHF8_MOUSE ---------------------MSKNDGEIRFGN----PAELHGP-----KVQIPYLTT-- REPS2_MOUSE REPS2_MOUSE ---------------------MSKNDGEIRFGN----PAELHGP-----KVQIPYLTT-- A2AFI8_MOUSE A2AFI8_MOUSE GLPVRTESIKC--ELPLPRFVMSKNDGEIRFGN----PAELHGP-----KVQIPYLTT-- B9EI38_MOUSE B9EI38_MOUSE GLPVRTESIKC--ELPLPRFVMSKNDGEIRFGN----PAELHGP-----KVQIPYLTT-- Q59H22_HUMAN Q59H22_HUMAN GLPVRIESIKC--ELPLPRFMMSKNDGEIRFGN----PAELHGT-----KVQIPYLTT-- B4DQQ8_HUMAN B4DQQ8_HUMAN --------------------MMSKNDGEIRFGN----PAELHGT-----KVQIPYLTT-- A6PWZ6_HUMAN A6PWZ6_HUMAN GLPVRIESIKC--ELPLPRFMMSKNDGEIRFGN----PAELHGT-----KVQIPYLTT-- REPS2_HUMAN REPS2_HUMAN GLPVRIESIKC--ELPLPRFMMSKNDGEIRFGN----PAELHGT-----KVQIPYLTT-- Q5JNZ8_HUMAN Q5JNZ8_HUMAN GLPVRIESIKC--ELPLPRFMMSKNDGEIRFGN----PAELHGT-----KVQIPYLTT-- MATCH CONSENSUS ???????????????????????K???E?R??????????????????????????????

Q5VSI7_DANRE Q5VSI7_DANRE QAKKVS-A-------HEMIQPCVPTADPQPDTTSPVVSPHQSPPTS--PLAWRKHKRQAS Q28CL0_XENTR Q28CL0_XENTR ------------------------------------------------------------ Q5GMN1_XENLA Q5GMN1_XENLA ------------------------------------------------------------ Q4S761_TETNG Q4S761_TETNG FQNKKGPASSTALPVHEVIQPLAASIEPQAEPTSPVVSPHQSPPTS--PHSWRKHKRQHS Q5ZK42_CHICK Q5ZK42_CHICK QVKKGSVS-------HDAVQQR-TSTDQ-QESTSPVVSPQQSPPTS--PHTWRKHNRHPS REPS1_MOUSE REPS1_MOUSE QVKKGPGS-------HDAVQPR-PSAEQ-QEPVSPVVSPQQSPPTS--PHTWRKHSRHPS A3KMX4_BOVIN A3KMX4_BOVIN QVKKGSTS-------HDTVQPR-ASVDQ-QEPVSPVVSPQQSPPAS--PHTWRKHNRHPS Q59GG6_HUMAN Q59GG6_HUMAN ------------------------------------------------------------ B2R7D3_HUMAN B2R7D3_HUMAN QVKKGSVS-------HDTVQPR-TSADA-QEPASPVVSPQQSPPTS--PHTWRKHSRHPS B7ZBZ8_HUMAN B7ZBZ8_HUMAN QVKKGSVS-------HDTVQPR-TSADA-QEPASPVVSPQQSPPTS--PHTWRKHSRHPS REPS1_HUMAN REPS1_HUMAN QVKKGSVS-------HDTVQPR-TSADA-QEPASPVVSPQQSPPTS--PHTWRKHSRHPS B7ZC00_HUMAN B7ZC00_HUMAN QVKKGSVS-------HDTVQPR-TSADA-QEPASPVVSPQQSPPTS--PHTWRKHSRHPS B7ZBZ9_HUMAN B7ZBZ9_HUMAN QVKKGSVS-------HDTVQPR-TSADA-QEPASPVVSPQQSPPTS--PHTWRKHSRHPS Q5JWJ8_HUMAN Q5JWJ8_HUMAN ------------------------------------------------------------ Q4SZC7_TETNG Q4SZC7_TETNG -------D-------RSAFPQLEASAKKARAGVKSASSPFQLCPVCLFNPEFVSAPLESV Q5ZII0_CHICK Q5ZII0_CHICK -------E-------KNSYKRT-DEGDK-QEPKSPPMSPICSPPAS--PSTYQRIPLTYG Q3UHE9_MOUSE Q3UHE9_MOUSE ----------------------------------------------------ERVSLSHG B1AV20_MOUSE B1AV20_MOUSE -------E-------KNSFKRM-DNEDK-QETQSPTMSPLASPPSS--PPHYQRVSLSHG Q3UHF8_MOUSE Q3UHF8_MOUSE -------E-------KNSFKRM-DNEDK-QETQSPTMSPLASPPSS--PPHYQRVSLSHG REPS2_MOUSE REPS2_MOUSE -------E-------KNSFKRM-DNEDKQQETQSPTMSPLASPPSS--PPHYQRVSLSHG A2AFI8_MOUSE A2AFI8_MOUSE -------E-------KNSFKRM-DNEDK-QETQSPTMSPLASPPSS--PPHYQRVSLSHG B9EI38_MOUSE B9EI38_MOUSE -------E-------KNSFKRM-DNEDKQQETQSPTMSPLASPPSS--PPHYQRVSLSHG Q59H22_HUMAN Q59H22_HUMAN -------E-------KNSFKRM-DDEDKQQETQSPTMSPLASPPSS--PPHYQRVPLSHG B4DQQ8_HUMAN B4DQQ8_HUMAN -------E-------KNSFKRM-DDEDK-QETQSPTMSPLASPPSS--PPHYQRVPLSHG A6PWZ6_HUMAN A6PWZ6_HUMAN -------E-------KNSFKRM-DDEDKQQETQSPTMSPLASPPSS--PPHYQRVPLSHG REPS2_HUMAN REPS2_HUMAN -------E-------KNSFKRM-DDEDKQQETQSPTMSPLASPPSS--PPHYQRVPLSHG Q5JNZ8_HUMAN Q5JNZ8_HUMAN -------E-------KNSFKRM-DDEDK-QETQSPTMSPLASPPSS--PPHYQRVPLSHG MATCH CONSENSUS ?????????????????????????????????????SP????P????????????????

Q5VSI7_DANRE Q5VSI7_DANRE GGNVDRQ--PSVPGVVW--PHFREAQ-PGPVPGDGMWSAHSPPPVQESWVSF-TDTPPSS Q28CL0_XENTR Q28CL0_XENTR ------------------------------------------------------------ Q5GMN1_XENLA Q5GMN1_XENLA ------------------------------------------------------------ Q4S761_TETNG Q4S761_TETNG GGNADRQPVVAAGGATW--TQFREPQ-TGVVPGEGMWSSHSPPLNQESWVSFTADTPPSS Q5ZK42_CHICK Q5ZK42_CHICK GGNNERP--LAGPGPFW--APFSEAQPGSSTSSDPIWSGHSPPPHQENWVSF-ADTPPTS REPS1_MOUSE REPS1_MOUSE GGNSERP--LTGPGPFW--SPFGDAQ-AGSSAGDAVWSGQSPPPPQDNWVSF-ADTPPTS A3KMX4_BOVIN A3KMX4_BOVIN GGNSERP--LAGPGPFW--SPFGEAQ-SGSSAGDAVWSGHSPPPPQENWVSF-ADTPPTS Q59GG6_HUMAN Q59GG6_HUMAN ------------------------------------------------------------ B2R7D3_HUMAN B2R7D3_HUMAN GGYSERP--LAGPGPFW--SPFGEAQ-SGSSAGDAVWSGHSPPPPQENWVSF-ADTPPTS B7ZBZ8_HUMAN B7ZBZ8_HUMAN GGNSERP--LAGPGPFW--SPFGEAQ-SGSSAGDAVWSGHSPPPPQENWVSF-ADTPPTS REPS1_HUMAN REPS1_HUMAN GGNSERP--LAGPGPFW--SPFGEAQ-SGSSAGDAVWSGHSPPPPQENWVSF-ADTPPTS B7ZC00_HUMAN B7ZC00_HUMAN GGNSERP--LAGPGPFW--SPFGEAQ-SGSSAGDAVWSGHSPPPPQENWVSF-ADTPPTS B7ZBZ9_HUMAN B7ZBZ9_HUMAN GGNSERP--LAGPGPFW--SPFGEAQ-SGSSAGDAVWSGHSPPPPQENWVSF-ADTPPTS Q5JWJ8_HUMAN Q5JWJ8_HUMAN ------------------------------------------------------------ Q4SZC7_TETNG Q4SZC7_TETNG FFMGLTLSLFFVFVFFFCAPAYESKHSSPSRYG--------------------------- Q5ZII0_CHICK Q5ZII0_CHICK YGKSRSGLEQQHGAPYEVRHSTHQQD-GSSSGN--------------------------- Q3UHE9_MOUSE Q3UHE9_MOUSE YSKLRSGTEQMHPAPHE-RQPIGQPE-GPSSEG--------------------------- B1AV20_MOUSE B1AV20_MOUSE YSKLRSGTEQMHPAPYE-RQPIGQPE-GPSSEG--------------------------- Q3UHF8_MOUSE Q3UHF8_MOUSE YSKLRSGTEQMHPAPYE-RQPIGQPE-GPSSEG--------------------------- REPS2_MOUSE REPS2_MOUSE YSKLRSGTEQMHPAPYE-RQPIGQPE-GPSSEG--------------------------- A2AFI8_MOUSE A2AFI8_MOUSE YSKLRSGTEQMHPAPYE-RQPIGQPE-GPSSEG--------------------------- B9EI38_MOUSE B9EI38_MOUSE YSKLRSGTEQMHPAPYE-RQPIGQPE-GPSSEG--------------------------- Q59H22_HUMAN Q59H22_HUMAN YSKLRSSAEQMHPAPYEARQPLVQPE-GSSSGG--------------------------- B4DQQ8_HUMAN B4DQQ8_HUMAN YSKLRSSAEQMHPAPYEARQPLVQPE-GSSSGG--------------------------- A6PWZ6_HUMAN A6PWZ6_HUMAN YSKLRSSAEQMHPAPYEARQPLVQPE-GSSSGG--------------------------- REPS2_HUMAN REPS2_HUMAN YSKLRSSAEQMHPAPYEARQPLVQPE-GSSSGG--------------------------- Q5JNZ8_HUMAN Q5JNZ8_HUMAN YSKLRSSAEQMHPAPYEARQPLVQPE-GSSSGG--------------------------- MATCH CONSENSUS ????????????????????????????????????????????????????????????

Q5VSI7_DANRE Q5VSI7_DANRE TLPMHPPSAQTESSTVRTVPSAMTTNEIQRQTSGYDD--PWKITDEQRQYYINQFKTIQA Q28CL0_XENTR Q28CL0_XENTR -------MSTTDQTTVRTVASSTTTNEIRRQSSSYDD--PWKITDEQRQYYINQFKNIQP Q5GMN1_XENLA Q5GMN1_XENLA ---------------------------------------EFGTRDEQRQYYINQFKNIQP Q4S761_TETNG Q4S761_TETNG TLPAVHPSSAQENTTVRTVASAATTNEIQRQSSGYDD--PWKITDEQRQYYINQFKTIQP Q5ZK42_CHICK Q5ZK42_CHICK ALLAMHPASVQDQTTVRTVASATTTNEIRRQSSSYDD--PWKITDEQRQYYVNQFKTIQP REPS1_MOUSE REPS1_MOUSE ALLTMHPASVQDQTTVRTVASAATANEIRRQSSSYED--PWKITDEQRQYYVNQFKTIQP A3KMX4_BOVIN A3KMX4_BOVIN TLLTMHPASVQDQTTVRTVASATTANEIRRQSSSYDD--PWKITDEQRQYYVNQFKTIQP Q59GG6_HUMAN Q59GG6_HUMAN ------------------------------------------------------------ B2R7D3_HUMAN B2R7D3_HUMAN TLLTMHPASVQDQTTVRTVASATTAIEIRRQSSSYDD--PWKITDEQRQYYVNQFKTIQP B7ZBZ8_HUMAN B7ZBZ8_HUMAN TLLTMHPASVQDQTTVRTVASATTAIEIRRQSSSYDD--PWKITDEQRQYYVNQFKTIQP REPS1_HUMAN REPS1_HUMAN TLLTMHPASVQDQTTVRTVASATTAIEIRRQSSSYDD--PWKITDEQRQYYVNQFKTIQP B7ZC00_HUMAN B7ZC00_HUMAN TLLTMHPASVQDQTTVRTVASATTAIEIRRQSSSYDD--PWKITDEQRQYYVNQFKTIQP B7ZBZ9_HUMAN B7ZBZ9_HUMAN TLLTMHPASVQDQTTVRTVASATTAIEIRRQSSSYDD--PWKITDEQRQYYVNQFKTIQP Q5JWJ8_HUMAN Q5JWJ8_HUMAN ---------------------------------------------------VNQFKTIQP Q4SZC7_TETNG Q4SZC7_TETNG --------PKPAAERASMARTCSSERLDPQTAADHPDSDPWRITEEQLEYYTNQFKSLQP Q5ZII0_CHICK Q5ZII0_CHICK ------YGAKPALACSTLSRSLSVEREQPDSSAHYSD-DPWRITEEQRDYYVNQFKSLQP Q3UHE9_MOUSE Q3UHE9_MOUSE ------PGAKPFRRQASLIRSFSVEREPQENNSNYPD-EPWRITEEQREYYVNQFRSLQP B1AV20_MOUSE B1AV20_MOUSE ------PGAKPFRRQASLIRSFSVEREPQENNSNYPD-EPWRITEEQREYYVNQFRSLQP Q3UHF8_MOUSE Q3UHF8_MOUSE ------PGAKPFRRQASLIRSFSVEREPQENNSNYPD-EPWRITEEQREYYVNQFRSLQP REPS2_MOUSE REPS2_MOUSE ------PGAKPFRRQASLIRSFSVEREPQENNSNYPD-EPWRITEEQREYYVNQFRSLQP A2AFI8_MOUSE A2AFI8_MOUSE ------PGAKPFRRQASLIRSFSVEREPQENNSNYPD-EPWRITEEQREYYVNQFRSLQP B9EI38_MOUSE B9EI38_MOUSE ------PGAKPFRRQASLIRSFSVEREPQENNSNYPD-EPWRITEEQREYYVNQFRSLQP Q59H22_HUMAN Q59H22_HUMAN ------PGTKPLRHQASLIRSFSVERELQ-DNSSYPD-EPWRITEEQREYYVNQFRSLQP B4DQQ8_HUMAN B4DQQ8_HUMAN ------PGTKPLRHQASLIRSFSVERELQ-DNSSYPD-EPWRITEEQREYYVNQFRSLQP A6PWZ6_HUMAN A6PWZ6_HUMAN ------PGTKPLRHQASLIRSFSVERELQ-DNSSYPD-EPWRITEEQREYYVNQFRSLQP REPS2_HUMAN REPS2_HUMAN ------PGTKPLRHQASLIRSFSVERELQ-DNSSYPD-EPWRITEEQREYYVNQFRSLQP Q5JNZ8_HUMAN Q5JNZ8_HUMAN ------PGTKPLRHQASLIRSFSVERELQ-DNSSYPD-EPWRITEEQREYYVNQFRSLQP MATCH CONSENSUS ????????????????????S?????E?????S?Y?D??PW?IT?EQR?YY?NQF???QP

Q5VSI7_DANRE Q5VSI7_DANRE DLTGLIPGSAAKEFFTKSKLPILELSHIWELSDFDKDGALTLDEFCAAFHLVVARKNGYD Q28CL0_XENTR Q28CL0_XENTR DLNGFIPGSSAKEFFTKSKLPIPELSHIWELSDFDKDGALTLDEFCAAFHLVVARKNGYD Q5GMN1_XENLA Q5GMN1_XENLA DLNGFIPGSAAKEFFTKSKLPIPELSHIWELSDFDKDGALTLDEFCAAFHLVVARKNGYD Q4S761_TETNG Q4S761_TETNG DLNGFIPGSAAKEFFTKSKLPILELSHIWELSDFDKDGALTLDEFCAAFHLVVARKNGYD Q5ZK42_CHICK Q5ZK42_CHICK DLNGFIPGSAAKEFFTKSKLPILELSHIWELSDFDKDGALTLDEFCAAFHLVVARKNGYD REPS1_MOUSE REPS1_MOUSE DLNGFIPGSAAKEFFTKSKLPILELSHIWELSDFDKDGALTLDEFCAAFHLVVARKNGYD A3KMX4_BOVIN A3KMX4_BOVIN DLNGFIPGSAAKEFFTKSKLPILELSHIWELSDFDKDGALTLDEFCAAFHLVVARKNGYD Q59GG6_HUMAN Q59GG6_HUMAN -----------------------DISHL--------------------------SADGYS B2R7D3_HUMAN B2R7D3_HUMAN DLNGFIPGSAAKEFFTKSKLPILELSHIWELSDFDKDGALTLDEFCAAFHLVVARKNGYD B7ZBZ8_HUMAN B7ZBZ8_HUMAN DLNGFIPGSAAKEFFTKSKLPILELSHIWELSDFDKDGALTLDEFCAAFHLVVARKNGYD REPS1_HUMAN REPS1_HUMAN DLNGFIPGSAAKEFFTKSKLPILELSHIWELSDFDKDGALTLDEFCAAFHLVVARKNGYD B7ZC00_HUMAN B7ZC00_HUMAN DLNGFIPGSAAKEFFTKSKLPILELSHIWELSDFDKDGALTLDEFCAAFHLVVARKNGYD B7ZBZ9_HUMAN B7ZBZ9_HUMAN DLNGFIPGSAAKEFFTKSKLPILELSHIWELSDFDKDGALTLDEFCAAFHLVVARKNGYD Q5JWJ8_HUMAN Q5JWJ8_HUMAN DLNGFIPGSAAKEFFTKSKLPILELSHIWELSDFDKDGALTLDEFCAAFHLVVARKNGYD Q4SZC7_TETNG Q4SZC7_TETNG DLGALILGSIAKNFFTKSKLPIPELSHIWELSDVDRDGALTFSEFCTAFHLIVARKNGYP Q5ZII0_CHICK Q5ZII0_CHICK DLNAFISGSVAKNFFTKSKLPIPELSHIWELSDVDCDGALTLPEFCAAFHLVVARKNGYQ Q3UHE9_MOUSE Q3UHE9_MOUSE DPSSFISGSVAKNFFTKSKLSIPELSYIWELSDADCDGALTLSEFCAAFHLIVARKNGYP B1AV20_MOUSE B1AV20_MOUSE DPSSFISGSVAKNFFTKSKLSIPELSYIWELSDADCDGALTLSEFCAAFHLIVARKNGYP Q3UHF8_MOUSE Q3UHF8_MOUSE DPSSFISGSVAKNFFTKSKLSIPELSYIWELSDADCDGALTLSEFCAAFHLIVARKNGYP REPS2_MOUSE REPS2_MOUSE DPSSFISGSVAKNFFTKSKLSIPELSYIWELSDADCDGALTLSEFCAAFHLIVARKNGYP A2AFI8_MOUSE A2AFI8_MOUSE DPSSFISGSVAKNFFTKSKLSIPELSYIWELSDADCDGALTLSEFCAAFHLIVARKNGYP B9EI38_MOUSE B9EI38_MOUSE DPSSFISGSVAKNFFTKSKLSIPELSYIWELSDADCDGALTLSEFCAAFHLIVARKNGYP Q59H22_HUMAN Q59H22_HUMAN DPSSFISGSVAKNFFTKSKLSIPELSYIWELSDADCDGALTLPEFCAAFHLIVARKNGYP B4DQQ8_HUMAN B4DQQ8_HUMAN DPSSFISGSVAKNFFTKSKLSIPELSYIWELSDADCDGALTLPEFCAAFHLIVARKNGYP A6PWZ6_HUMAN A6PWZ6_HUMAN DPSSFISGSVAKNFFTKSKLSIPELSYIWELSDADCDGALTLPEFCAAFHLIVARKNGYP REPS2_HUMAN REPS2_HUMAN DPSSFISGSVAKNFFTKSKLSIPELSYIWELSDADCDGALTLPEFCAAFHLIVARKNGYP Q5JNZ8_HUMAN Q5JNZ8_HUMAN DPSSFISGSVAKNFFTKSKLSIPELSYIWELSDADCDGALTLPEFCAAFHLIVARKNGYP MATCH ::*:: :** CONSENSUS D???FI?GS?AK?FFTKSKL?I?ELS?IWELSD?D?DGALTL?EFCAAFHL?VARKNGY?

Q5VSI7_DANRE Q5VSI7_DANRE LPEKLPESLMPKLIDLDDSA-GVPEPAPEVGFSASPVEVTPNKSPSMPSLNQNWPELNQS Q28CL0_XENTR Q28CL0_XENTR LPEKLPESLMPKLID-LDDG-TAGDQTTDVGFTSSPAEAPPSKSPSMPSLNQTWPEMNQS Q5GMN1_XENLA Q5GMN1_XENLA LPEKLPESLMPKLIDLDDGT--AGDQTTEVGFISSPAEAPPSKSPSMPSLNQTWPEMNQS Q4S761_TETNG Q4S761_TETNG LPEKLPESLMPKLIDLDDSA-DIPEQAPDVGYSGSPVEVTPNKSPSMPSLNQAWPEMNQS Q5ZK42_CHICK Q5ZK42_CHICK LPEKLPESLMPKLIDLEDST-EVGEQTGEVGYSSSPAEAPPSKSPSMPSLNQTWPELNQS REPS1_MOUSE REPS1_MOUSE LPEKLPESLMPKLIDLEDSA-DVGEQPGEVGYSGSPAEAPPSKSPSMPSLNQTWPELNQS A3KMX4_BOVIN A3KMX4_BOVIN LPEKLPESLMPKLIDLEDSA-DVGDQPGEVGYSGSPAEAPPSKSPSMPSLNQTWPELNQS Q59GG6_HUMAN Q59GG6_HUMAN ------------------------------------------------------------ B2R7D3_HUMAN B2R7D3_HUMAN LPEKLPESLMPKLIDLEDSA-DVGDQPGEVGYSGSPAEAPPSKSPSMPSLNQTWPELNQS B7ZBZ8_HUMAN B7ZBZ8_HUMAN LPEKLPESLMPKLIDLEDSA-DVGDQPGEVGYSGSPAEAPPSKSPSMPSLNQTWPELNQS REPS1_HUMAN REPS1_HUMAN LPEKLPESLMPKLIDLEDSA-DVGDQPGEVGYSGSPAEAPPSKSPSMPSLNQTWPELNQS B7ZC00_HUMAN B7ZC00_HUMAN LPEKLPESLMPKLIDLEDSA-DVGDQPGEVGYSGSPAEAPPSKSPSMPSLNQTWPELNQS B7ZBZ9_HUMAN B7ZBZ9_HUMAN LPEKLPESLMPKLIDLEDSA-DVGDQPGEVGYSGSPAEAPPSKSPSMPSLNQTWPELNQS Q5JWJ8_HUMAN Q5JWJ8_HUMAN LPEKLPESLMPKLIDLEDSA-DVGDQPGEVGYSGSPAEAPPSKSPSMPSLNQTWPELNQS Q4SZC7_TETNG Q4SZC7_TETNG LPESLPPTLRAGFVQQNDEAPETPESPKPLIVFE--------DAEPRPSQKVGHGSSSSA Q5ZII0_CHICK Q5ZII0_CHICK LPETLPETLLPDYLQ----A-ASLKPLHECALFDSYSEPLPSGQPTRDFSRMEKTSTEEV Q3UHE9_MOUSE Q3UHE9_MOUSE LPEGLPPTLQPEYLQ----A-AFPKSKWECAIFDSYSESMPANQQSCDLNRMEKTSVKDV B1AV20_MOUSE B1AV20_MOUSE LPEGLPPTLQPEYLQ----A-AFPKSKWECAIFDSYSESMPANQQSCDLNRME-TSVKDV Q3UHF8_MOUSE Q3UHF8_MOUSE LPEGLPPTLQPEYLQ----A-AFPKSKWECAIFDSYSESMPANQQSCDLNRME-TSVKDV REPS2_MOUSE REPS2_MOUSE LPEGLPPTLQPEYLQ----A-AFPKSKWECAIFDSYSESMPANQQSCDLNRMEKTSVKDV A2AFI8_MOUSE A2AFI8_MOUSE LPEGLPPTLQPEYLQ----A-AFPKSKWECAIFDSYSESMPANQQSCDLNRMEKTSVKDV B9EI38_MOUSE B9EI38_MOUSE LPEGLPPTLQPEYLQ----A-AFPKSKWECAIFDSYSESMPANQQSCDLNRMEKTSVKDV Q59H22_HUMAN Q59H22_HUMAN LPEGLPPTLQPEYLQ----A-AFPKPKWDCQLFDSYSESLPANQQPRDLNRMEKTSVKDM B4DQQ8_HUMAN B4DQQ8_HUMAN LPEGLPPTLQPEYLQ----A-AFPKPKWDCQLFDSYSESLPANQQPRDLNRMEKTSVKDM A6PWZ6_HUMAN A6PWZ6_HUMAN LPEGLPPTLQPEYLQ----A-AFPKPKWDCQLFDSYSESLPANQQPRDLNRMEKTSVKDM REPS2_HUMAN REPS2_HUMAN LPEGLPPTLQPEYLQ----A-AFPKPKWDCQLFDSYSESLPANQQPRDLNRMEKTSVKDM Q5JNZ8_HUMAN Q5JNZ8_HUMAN LPEGLPPTLQPEYLQ----A-AFPKPKWDCQLFDSYSESLPANQQPRDLNRMEKTSVKDM MATCH CONSENSUS LPE?LP??L?P????????A??????????????S??E??P???????????????????

Q5VSI7_DANRE Q5VSI7_DANRE NE----------------------------------------QWETFSERSSSSQTLTQF Q28CL0_XENTR Q28CL0_XENTR SE----------------------------------------QWETFSERSSSSQTLTQF Q5GMN1_XENLA Q5GMN1_XENLA TE----------------------------------------QWETFSERSSSSQTLTQF Q4S761_TETNG Q4S761_TETNG NEVSAHTSHSLLPAFFASICFHPTVVSPGCSVHFMATSSPSWQWETFSERSSSSQTLTQF Q5ZK42_CHICK Q5ZK42_CHICK SE---------------------------------------------------------- REPS1_MOUSE REPS1_MOUSE SE----------------------------------------QWETFSERSSSSQTLTQF A3KMX4_BOVIN A3KMX4_BOVIN SE---------------------------------------------------------- Q59GG6_HUMAN Q59GG6_HUMAN ------------------------------------------------------------ B2R7D3_HUMAN B2R7D3_HUMAN SE----------------------------------------QWETFSERSSSSQTLTQF B7ZBZ8_HUMAN B7ZBZ8_HUMAN SE----------------------------------------QWETFSERSSSSQTLTQF REPS1_HUMAN REPS1_HUMAN SE----------------------------------------QWETFSERSSSSQTLTQF B7ZC00_HUMAN B7ZC00_HUMAN SE----------------------------------------QWETFSERSSSSQTLTQF B7ZBZ9_HUMAN B7ZBZ9_HUMAN SE---------------------------------------------------------- Q5JWJ8_HUMAN Q5JWJ8_HUMAN SE---------------------------------------------------------- Q4SZC7_TETNG Q4SZC7_TETNG QD---------------------------------------------------------- Q5ZII0_CHICK Q5ZII0_CHICK PD---------------------------------------------------------- Q3UHE9_MOUSE Q3UHE9_MOUSE AD---------------------------------------------------------- B1AV20_MOUSE B1AV20_MOUSE AD---------------------------------------------------------- Q3UHF8_MOUSE Q3UHF8_MOUSE AD---------------------------------------------------------- REPS2_MOUSE REPS2_MOUSE AD---------------------------------------------------------- A2AFI8_MOUSE A2AFI8_MOUSE AD---------------------------------------------------------- B9EI38_MOUSE B9EI38_MOUSE AD---------------------------------------------------------- Q59H22_HUMAN Q59H22_HUMAN AD---------------------------------------------------------- B4DQQ8_HUMAN B4DQQ8_HUMAN AD---------------------------------------------------------- A6PWZ6_HUMAN A6PWZ6_HUMAN AD---------------------------------------------------------- REPS2_HUMAN REPS2_HUMAN AD---------------------------------------------------------- Q5JNZ8_HUMAN Q5JNZ8_HUMAN AD---------------------------------------------------------- MATCH CONSENSUS ????????????????????????????????????????????????????????????

Q5VSI7_DANRE Q5VSI7_DANRE DSNIAPADPDTAIVHPVPIRMTPSKIHMQEMELKRTGSDHTHPTSPLMTKPPELSDETKL Q28CL0_XENTR Q28CL0_XENTR DSNIAPADPDTAIVHPVPIRMTPSKIHMQEMELKRTASDPANSKSPLHMKPQELSEESTL Q5GMN1_XENLA Q5GMN1_XENLA DSNIAPADPDTAIVHPVPIRMTPSKIHMQEMELKRTASDPANPTSPLHMKQQELSDESNL Q4S761_TETNG Q4S761_TETNG DSNIAPADPDTAIVHPVPIRMTPSKIHMQEMELKRTGSDHNHPTSPLLAKPPELAEEVKL Q5ZK42_CHICK Q5ZK42_CHICK ---------DTAIVHPVPIRMTPSKIHMQEMELKRTGSDHTNPTSPLLVKPPDLPEENKM REPS1_MOUSE REPS1_MOUSE DSNIAPADPDTAIVHPVPIRMTPSKIHMQEMELKRTSSDHTNPTSPLLVKPSDLSEENKI A3KMX4_BOVIN A3KMX4_BOVIN ---------DTAIVHPVPIRMTPSKIHMQEMELKRTGSDHTNPTSPLLVKTSDLSEENKI Q59GG6_HUMAN Q59GG6_HUMAN ------------------------------------------------------------ B2R7D3_HUMAN B2R7D3_HUMAN DSNIAPADPDTAIVHPVPIRMTPSKIHMQEMELKRTGSDHTNPTSPLLVKPSDLLEENKI B7ZBZ8_HUMAN B7ZBZ8_HUMAN DSNIAPADPDTAIVHPVPIRMTPSKIHMQEMELKRTGSDHTNPTSPLLVKPSDLLEENKI REPS1_HUMAN REPS1_HUMAN DSNIAPADPDTAIVHPVPIRMTPSKIHMQEMELKRTGSDHTNPTSPLLVKPSDLLEENKI B7ZC00_HUMAN B7ZC00_HUMAN DSNIAPADPDTAIVHPVPIRMTPSKIHMQEMELKRTGSDHTNPTSPLLVKPSDLLEENKI B7ZBZ9_HUMAN B7ZBZ9_HUMAN ---------DTAIVHPVPIRMTPSKIHMQEMELKRTGSDHTNPTSPLLVKPSDLLEENKI Q5JWJ8_HUMAN Q5JWJ8_HUMAN ---------DTAIVHPVPIRMTPSKIHMQEMELKRTGSDHTNPTSPLLVKPSDLLEENKI Q4SZC7_TETNG Q4SZC7_TETNG --------------RVIEKLESNLRGDKQELKKEKCSKDVMKRVLTSEEKPQRP------ Q5ZII0_CHICK Q5ZII0_CHICK --------------NSALIKD-TSKDDKQALKVSTTVK----------AIPKEF------ Q3UHE9_MOUSE Q3UHE9_MOUSE --------------FPVPTQDVTTADDKQALKSTVNES-----------LPKDV------ B1AV20_MOUSE B1AV20_MOUSE --------------FPVPTQDVTTADDKQALKSTVNES-----------LPKDV------ Q3UHF8_MOUSE Q3UHF8_MOUSE --------------FPVPTQDVTTADDKQALKSTVNES-----------LPKDV------ REPS2_MOUSE REPS2_MOUSE --------------FPVPTQDVTTADDKQALKSTVNES-----------LPKDV------ A2AFI8_MOUSE A2AFI8_MOUSE --------------FPVPTQDVTTADDKQALKSTVNES-----------LPKDV------ B9EI38_MOUSE B9EI38_MOUSE --------------FPVPTQDVTTADDKQALKSTVNES-----------LPKDV------ Q59H22_HUMAN Q59H22_HUMAN --------------LPVPNQDVTS-DDKQALKSTINEA-----------LPKDV------ B4DQQ8_HUMAN B4DQQ8_HUMAN --------------LPVPNQDVTS-DDKQALKSTINEA-----------LPKDV------ A6PWZ6_HUMAN A6PWZ6_HUMAN --------------LPVPNQDVTS-DDKQALKSTINEA-----------LPKDV------ REPS2_HUMAN REPS2_HUMAN --------------LPVPNQDVTS-DDKQALKSTINEA-----------LPKDV------ Q5JNZ8_HUMAN Q5JNZ8_HUMAN --------------LPVPNQDVTS-DDKQALKSTINEA-----------LPKDV------ MATCH CONSENSUS ???????????????PVP??????????Q?????????????????????P?????????

Q5VSI7_DANRE Q5VSI7_DANRE AAAIKFP-GTAVGDGYSSSDSFTSDQEPISSAV-NRQRSHSGTSPEGLKVVA--PPPPPP Q28CL0_XENTR Q28CL0_XENTR NSSVKFISGNSVADGYNSSDSFNSEPEEIENVA-TRQRSHSSTSPDNTA-----PPPPPP Q5GMN1_XENLA Q5GMN1_XENLA NSSVKFVSGNSGADGYNSSDSFNSEPEDVENVA-ARQRSHSSTSPDNTAPP---PPPPPP Q4S761_TETNG Q4S761_TETNG PPSMKFVAANTVGDGYSSSDSFTSDQEPI-----ARQRSQSGTSPDALKVVA--PPPPPP Q5ZK42_CHICK Q5ZK42_CHICK SSSVKYTSGNTVTDGYSSSDSYTSDPEQIGSAV-TRQRSHSGTSPDNTA-----PPPPPP REPS1_MOUSE REPS1_MOUSE NSSVKFPSGNTV-DGYSSSDSFPSDPEQIGSSV-TRQRSHSGTSPDNTA-----PPPPPP A3KMX4_BOVIN A3KMX4_BOVIN NSSVKFASGNTVADGYSSSDSFTSDPEQIGNNV-TRQRSHSGTSPENTA-----PPPPPP Q59GG6_HUMAN Q59GG6_HUMAN -----------------SSDSFTSDPEQIGSNV-TRQRSHSGTSPDNTA-----PPPPPP B2R7D3_HUMAN B2R7D3_HUMAN NSSVKFASGNTVADGYSSSDSFTSDPEQIGSNV-TRQRSHSGTSPDNTA-----PPPPPP B7ZBZ8_HUMAN B7ZBZ8_HUMAN NSSVKFASGNTVADGYSSSDSFTSDPEQIGSNV-TRQRSHSGTSPDNTA-----PPPPPP REPS1_HUMAN REPS1_HUMAN NSSVKFASGNTVADGYSSSDSFTSDPEQIGSNV-TRQRSHSGTSPDNTA-----PPPPPP B7ZC00_HUMAN B7ZC00_HUMAN NSSVKFASGNTV-DGYSSSDSFTSDPEQIGSNV-TRQRSHSGTSPDNTA-----PPPPPP B7ZBZ9_HUMAN B7ZBZ9_HUMAN NSSVKFASGN-------------------------------------------------- Q5JWJ8_HUMAN Q5JWJ8_HUMAN NSSVKFASGNTVADGYSSSDSFTSDPEQIGSNV-TRQRSHSGTSPDNTA-----PPPPPP Q4SZC7_TETNG Q4SZC7_TETNG ----------------GAPDILHPGVAAWLHGVSPDSRSYSSTSFEDAVKKAEEPPTPPP Q5ZII0_CHICK Q5ZII0_CHICK --------------QHLTVKTAAQEP-HALKAR-PRSRSYSSTSIEDAMKKGEEPPTPPP Q3UHE9_MOUSE Q3UHE9_MOUSE -----------------SEDTATSKDYNSLKAR-PRSRSYSSTSIEEAMKRGEDPPTPPP B1AV20_MOUSE B1AV20_MOUSE -----------------SEDT--------------------------------------- Q3UHF8_MOUSE Q3UHF8_MOUSE -----------------SEDT--------------------------------------- REPS2_MOUSE REPS2_MOUSE -----------------SEDTATSKDYNSLKAR-PRSRSYSSTSIEEAMKRGEDPPTPPP A2AFI8_MOUSE A2AFI8_MOUSE -----------------SEDTATSKDYNSLKAR-PRSRSYSSTSIEEAMKRGEDPPTPPP B9EI38_MOUSE B9EI38_MOUSE -----------------SEDTATSKDYNSLKAR-PRSRSYSSTSIEEAMKRGEDPPTPPP Q59H22_HUMAN Q59H22_HUMAN -----------------SEDPATPKDSNSLKAR-PRSRSYSSTSIEEAMKRGEDPPTPPP B4DQQ8_HUMAN B4DQQ8_HUMAN -----------------SED---------------------------------------- A6PWZ6_HUMAN A6PWZ6_HUMAN -----------------SEDPATPKDSNSLKAR-PRSRSYSSTSIEEAMKRGEDPPTPPP REPS2_HUMAN REPS2_HUMAN -----------------SEDPATPKDSNSLKAR-PRSRSYSSTSIEEAMKRGEDPPTPPP Q5JNZ8_HUMAN Q5JNZ8_HUMAN -----------------SEDPATPKDSNSLKAR-PRSRSYSSTSIEEAMKRGEDPPTPPP MATCH CONSENSUS ?????????????????S?D???????????????R?RS?S?TS??????????PP?PPP

Q5VSI7_DANRE Q5VSI7_DANRE RPHASHSRSSSLDMNRNFAAVPAGSQ-QAGVVAFP-PAVPPRPLPTQTSVPHGHRSVEGD Q28CL0_XENTR Q28CL0_XENTR RPHASHSRSSSLDMNRTFAVTTAGQQ-QATTVVQP-PAVPPRPLPTQTSGSHMHRSVESE Q5GMN1_XENLA Q5GMN1_XENLA RPQASHSRSSSLDMNRTFSITTAGQQ-QATTVVHP-PAVPPRPLPTQTSGSHMHRSMESE Q4S761_TETNG Q4S761_TETNG RPHPSHSRSSSLDMNRTFAASSTPGQPQSSTTAYP-PAVPPRPLPTQ------------- Q5ZK42_CHICK Q5ZK42_CHICK RPHPSHSRSSSLDMNRSFSV-TPGQQ-QAAVVAYP-PAVPPRPQPSQGAGPHVHRPVDAD REPS1_MOUSE REPS1_MOUSE RPQPSHSRSSSLDMNRTFAV-TTGQQ-QAGVVAHP-PAVPPRPQPSQAPGPSVHRPVDAD A3KMX4_BOVIN A3KMX4_BOVIN RPQPSHSRSSSLDMNRTFSV-TTGQQ-QAGVVAQP-PAVPPRPQPSQAPGPVVHRPVDAD Q59GG6_HUMAN Q59GG6_HUMAN RPQPSHSRSSSLDMNRTFTV-TTGQQ-QAGVVAHP-PAVPPRPQPSQAPGPAVHRPVDAD B2R7D3_HUMAN B2R7D3_HUMAN RPQPSHSRSSSLDMNRTFTV-TTGQQ-QAGVVAHP-PAVPPRPQPSQAPGPAEHRPVDAD B7ZBZ8_HUMAN B7ZBZ8_HUMAN RPQPSHSRSSSLDMNRTFTV-TTGQQ-QAGVVAHP-PAVPPRPQPSQAPGPAVHRPVDAD REPS1_HUMAN REPS1_HUMAN RPQPSHSRSSSLDMNRTFTV-TTGQQ-QAGVVAHP-PAVPPRPQPSQAPGPAVHRPVDAD B7ZC00_HUMAN B7ZC00_HUMAN RPQPSHSRSSSLDMNRTFTV-TTGQQ-QAGVVAHP-PAVPPRPQPSQAPGPAVHRPVDAD B7ZBZ9_HUMAN B7ZBZ9_HUMAN ---------------------TVGQQ-QAGVVAHP-PAVPPRPQPSQAPGPAVHRPVDAD Q5JWJ8_HUMAN Q5JWJ8_HUMAN RPQPSHSRSSSLDMNRTFTV-TTGQQ-QAGVVAHP-PAVPPRPQPSQ------------- Q4SZC7_TETNG Q4SZC7_TETNG RPQKSHSRASSLDLNKLFQQ-GAPGV-KSGWLPPP-PALPPRPSTSQVGSAHARLPLDQS Q5ZII0_CHICK Q5ZII0_CHICK RPQKSHSRASSLDLNKIFQQ-NTQAV-RSGWLPPPLPALPPRPSVSQT------EQVSEV Q3UHE9_MOUSE Q3UHE9_MOUSE RPQKTHSRASSLDLNKVFLP-SAPAA-NSGLLPPP-PALPPRPCPTQS------EPVSEA B1AV20_MOUSE B1AV20_MOUSE ------------------------AA-NSGLLPPP-PALPPRPCPTQS------EPVSEA Q3UHF8_MOUSE Q3UHF8_MOUSE ------------------------AA-NSGLLPPP-PALPPRPCPTQS------EPVSEA REPS2_MOUSE REPS2_MOUSE RPQKTHSRASSLDLNKVFLP-SAPAA-NSGLLPPP-PALPPRPCPTQS------EPVSEA A2AFI8_MOUSE A2AFI8_MOUSE RPQKTHSRASSLDLNKVFLP-SAPAA-NSGLLPPP-PALPPRPCPTQS------EPVSEA B9EI38_MOUSE B9EI38_MOUSE RPQKTHSRASSLDLNKVFLP-SAPAA-NSGLLPPP-PALPPRPCPTQS------EPVSEA Q59H22_HUMAN Q59H22_HUMAN RPQKTHSRASSLDLNKVFQP-SVPAT-KSGLLPPP-PALPPRPCPSQS------EQVSEA B4DQQ8_HUMAN B4DQQ8_HUMAN -----------------------PAT-KSGLLPPP-PALPPRPCPSQS------EQVSEA A6PWZ6_HUMAN A6PWZ6_HUMAN RPQKTHSRASSLDLNKVFQP-SVPAT-KSGLLPPP-PALPPRPCPSQS------EQVSEA REPS2_HUMAN REPS2_HUMAN RPQKTHSRASSLDLNKVFQP-SVPAT-KSGLLPPP-PALPPRPCPSQS------EQVSEA Q5JNZ8_HUMAN Q5JNZ8_HUMAN RPQKTHSRASSLDLNKVFQP-SVPAT-KSGLLPPP-PALPPRPCPSQS------EQVSEA MATCH .: * **:**** :* CONSENSUS RP???HSR?SSLD?N??F???????????G????P?PA?PPRP?P?Q?????????V???

Q5VSI7_DANRE Q5VSI7_DANRE --GLPAHTSTSPQQMPEQPNFADFSQFKAF----AVDQPADDGENPSDGGQAERLPEAAG Q28CL0_XENTR Q28CL0_XENTR --GVMSHPSTSPQQMPEQPNFADFSQFEAFSC--VTEQSSDDSEKHTEVASVEKSS--SD Q5GMN1_XENLA Q5GMN1_XENLA --SVMSHSSTSPQQMPEQPNFADFSQFEAFASC-VTEQSSDDSENHTEVAQVEKSS--SD Q4S761_TETNG Q4S761_TETNG ------------------------------------------------------------ Q5ZK42_CHICK Q5ZK42_CHICK --GLISHTSTSPQQIPEQPNFADFSQFEAFAASGVNKEEDDEIETHSEALQ--------- REPS1_MOUSE REPS1_MOUSE --GLITHTSTSPQQIPEQPNFADFSQFEVFAASNVSEEQDSEAEKHPEVLPAEKASDPSS A3KMX4_BOVIN A3KMX4_BOVIN --GLITHTSTSPQQIPEQPNFADFSQFEVFAASNVNEEQDDEAEKHPEVLPVEKSSDPAS Q59GG6_HUMAN Q59GG6_HUMAN --GLITHTSTSPQQIPEQPNFADFSQFEVFAASNVNDEQDDEAEKHPEVLPAEKASDPAS B2R7D3_HUMAN B2R7D3_HUMAN --GLITHTSTSPQQIPEQPNFADFSQFEVFAASNVNDEQDDEAEKHPEVLPAEKASDPAS B7ZBZ8_HUMAN B7ZBZ8_HUMAN --GLITHTSTSPQQIPEQPNFADFSQFEVFAASNVNDEQDDEAEKHPEVLPAEKASDPAS REPS1_HUMAN REPS1_HUMAN --GLITHTSTSPQQIPEQPNFADFSQFEVFAASNVNDEQDDEAEKHPEVLPAEKASDPAS B7ZC00_HUMAN B7ZC00_HUMAN --GLITHTSTSPQQIPEQPNFADFSQFEVFAASNVNDEQDDEAEKHPEVLPAEKASDPAS B7ZBZ9_HUMAN B7ZBZ9_HUMAN --GLITHTSTSPQQIPEQPNFADFSQFEVFAASNVNDEQDDEAEKHPEVLPAEKASDPAS Q5JWJ8_HUMAN Q5JWJ8_HUMAN ------------------------------------------------------------ Q4SZC7_TETNG Q4SZC7_TETNG SKGRVVPLNSTIFSFCQR-----------------------FGDDAPEKGAAAQLCRLQP Q5ZII0_CHICK Q5ZII0_CHICK --ELHPQMNRPPSQ---------------------------AEENSS------------- Q3UHE9_MOUSE Q3UHE9_MOUSE --DLHSQLNRAPSQ---------------------------AAESSP------------- B1AV20_MOUSE B1AV20_MOUSE --DLHSQLNRAPSQ---------------------------AAESSP------------- Q3UHF8_MOUSE Q3UHF8_MOUSE --DLHSQLNRAPSQ---------------------------AAESSP------------- REPS2_MOUSE REPS2_MOUSE --DLHSQLNRAPSQ---------------------------AAESSP------------- A2AFI8_MOUSE A2AFI8_MOUSE --DLHSQLNRAPSQ---------------------------AAESSP------------- B9EI38_MOUSE B9EI38_MOUSE --DLHSQLNRAPSQ---------------------------AAESSP------------- Q59H22_HUMAN Q59H22_HUMAN --ELLPQLSRAPSQ---------------------------AAESSP------------- B4DQQ8_HUMAN B4DQQ8_HUMAN --ELLPQLSRAPSQ---------------------------AAESSP------------- A6PWZ6_HUMAN A6PWZ6_HUMAN --ELLPQLSRAPSQ---------------------------AAESSP------------- REPS2_HUMAN REPS2_HUMAN --ELLPQLSRAPSQ---------------------------AAESSP------------- Q5JNZ8_HUMAN Q5JNZ8_HUMAN --ELLPQLSRAPSQ---------------------------AAESSP------------- MATCH CONSENSUS ???L???????P?Q?????????????????????????????E????????????????

Q5VSI7_DANRE Q5VSI7_DANRE TMRTAKNDVQAEERNATTV--NSAKVSTPLA-PPPKPVRRRLKSEDE--LRPDVDDLPQK Q28CL0_XENTR Q28CL0_XENTR SVRASKLNGLVEEKSVTAVSVNSGKIGTPLA-PPPKPVRRRLKSEDE--LRSEAEEHNQK Q5GMN1_XENLA Q5GMN1_XENLA TIGVSKLNGLVEEKSVTAVSVNSSKIGTPLA-PPPKPVRRRLKSEDE--LRPEAEEHDQK Q4S761_TETNG Q4S761_TETNG ------------------------------------------------------------ Q5ZK42_CHICK Q5ZK42_CHICK -----------------------GKGTTPLA-PPPKPIRRRLKSEDE--LRPEAEEHTQK REPS1_MOUSE REPS1_MOUSE SLRAAQADSKAEEKTATNVPANVSKGTTPLA-PPPKPVRRRLKSEDE--LRPDVDEHTQK A3KMX4_BOVIN A3KMX4_BOVIN S-RVAKTDSKIEEKTAASAPANVSKGTTPLA-PPPKPVRRRLKSEDE--LRPEVDEHTQK Q59GG6_HUMAN Q59GG6_HUMAN SLRVAKTDSKTEEKTAASAPANVSKGTTPLA-PPPKPVRRRLKSEDE--LRPEIDEHTQK B2R7D3_HUMAN B2R7D3_HUMAN SLRVAKTDSKTEEKTAASAPANVSKGTTPLA-PPPKPVRRRLKSEDE--LRPEVDEHTQK B7ZBZ8_HUMAN B7ZBZ8_HUMAN SLRVAKTDSKTEEKTAASAPANVSKGTTPLA-PPPKPVRRRLKSEDE--LRPEVDEHTQK REPS1_HUMAN REPS1_HUMAN SLRVAKTDSKTEEKTAASAPANVSKGTTPLA-PPPKPVRRRLKSEDE--LRPEVDEHTQK B7ZC00_HUMAN B7ZC00_HUMAN SLRVAKTDSKTEEKTAASAPANVSKGTTPLA-PPPKPVRRRLKSEDE--LRPEVDEHTQK B7ZBZ9_HUMAN B7ZBZ9_HUMAN SLRVAKTDSKTEEKTAASAPANVSKGTTPLA-PPPKPVRRRLKSEDE--LRPEVDEHTQK Q5JWJ8_HUMAN Q5JWJ8_HUMAN ------------------------------------------------------------ Q4SZC7_TETNG Q4SZC7_TETNG LQ---------------------RGVGVSHSYAPQKPARRRYQAENQ--SVEAVPP---- Q5ZII0_CHICK Q5ZII0_CHICK -----------------------AKKEVVLAQQPSKPARRKLRTEVQGLETPELSPTVNV Q3UHE9_MOUSE Q3UHE9_MOUSE -----------------------TKMDAPHAQPPSKPIRRKFRPENQ--TTESQEPAAAV B1AV20_MOUSE B1AV20_MOUSE -----------------------TKMDAPHAQPPSKPIRRKFRPENQ--TTESQEPAAAV Q3UHF8_MOUSE Q3UHF8_MOUSE -----------------------TKMDAPHAQPPSKPIRRKFRPENQ--TTESQEPAAAV REPS2_MOUSE REPS2_MOUSE -----------------------TKMDAPHAQPPSKPIRRKFRPENQ--TTESQEPAAAV A2AFI8_MOUSE A2AFI8_MOUSE -----------------------TKMDAPHAQPPSKPIRRKFRPENQ--TTESQEPAAAV B9EI38_MOUSE B9EI38_MOUSE -----------------------TKMDAPHAQPPSKPIRRKFRPENQ--TTESQEPAAAV Q59H22_HUMAN Q59H22_HUMAN -----------------------AKKDVLYSQPPSKPIRRKFRP---------------- B4DQQ8_HUMAN B4DQQ8_HUMAN -----------------------AKKDVLYSQPPSKPIRRKFRPENQ--ATENQEPSTAA A6PWZ6_HUMAN A6PWZ6_HUMAN -----------------------AKKDVLYSQPPSKPIRRKFRPENQ--ATENQEPSTAA REPS2_HUMAN REPS2_HUMAN -----------------------AKKDVLYSQPPSKPIRRKFRPENQ--ATENQEPSTAA Q5JNZ8_HUMAN Q5JNZ8_HUMAN -----------------------AKKDVLYSQPPSKPIRRKFRPENQ--ATENQEPSTAA MATCH CONSENSUS ????????????????????????K???????PP?KP?RR????E???????????????

Q5VSI7_DANRE Q5VSI7_DANRE SNVI-ATVLATQPSIPRSLGKDKKAIQASIRRNKETNTVLARLNSELQQQLKDLLEERIS Q28CL0_XENTR Q28CL0_XENTR TSTA-PTAIAPQPSIPRSAGKDKKAIQASIRRNKETNTVLARLNSELQQQLKDVLEERIS Q5GMN1_XENLA Q5GMN1_XENLA SSTA-CTTITPQPSIPRSAGKDKKAIQASIRRNKETNTVLARLNSELQQQLKDVLEERIS Q4S761_TETNG Q4S761_TETNG ------------------------------------------------------------ Q5ZK42_CHICK Q5ZK42_CHICK TGVI-AAVLASQPSIPRSIGKDKKAIQASIRRNKETNTVLARLNSELQQQLKDVLEERIS REPS1_MOUSE REPS1_MOUSE TGVL-AAVLTSQPSIPRSVGKDKKAIQASIRRNKETNTVLARLNSELQQQLKDVLEERIS A3KMX4_BOVIN A3KMX4_BOVIN TGVL-AAVLASQPSIPRSVGKDKKAIQASIRRNKETNTVLARLNSELQQQLKDVLEERIS Q59GG6_HUMAN Q59GG6_HUMAN TGVL-AAVLASQPSIPRSVGKDKKAIQASIRRNKETNTVLARLNSELQQQLKDVLEERIS B2R7D3_HUMAN B2R7D3_HUMAN TGVL-AAVLASQPSIPRSVGKDKKAIQASIRRNKETNTVLARLNSELQQQLKDVLEERIS B7ZBZ8_HUMAN B7ZBZ8_HUMAN TGVL-AAVLASQPSIPRSVGKDKKAIQASIRRNKETNTVLARLNSELQQQLKDVLEERIS REPS1_HUMAN REPS1_HUMAN TGVL-AAVLASQPSIPRSVGKDKKAIQASIRRNKETNTVLARLNSELQQQLKDVLEERIS B7ZC00_HUMAN B7ZC00_HUMAN TGVL-AAVLASQPSIPRSVGKDKKAIQASIRRNKETNTVLARLNSELQQQLKDVLEERIS B7ZBZ9_HUMAN B7ZBZ9_HUMAN TGVL-AAVLASQPSIPRSVGKDKKAIQASIRRNKETNTVLARLNSELQQQLKDVLEERIS Q5JWJ8_HUMAN Q5JWJ8_HUMAN ------------------------------------------------------------ Q4SZC7_TETNG Q4SZC7_TETNG -----PSTSFPTKSAQKLQPRQRREIQMAIRKNKETNAVLTRLNSELQQQLKAALCKGCT Q5ZII0_CHICK Q5ZII0_CHICK TSSLPAA--KPHLPVQKQSSKQKRAIQTAIRKNKEANAVLTRLNSELQQQLKEVHKERIA Q3UHE9_MOUSE Q3UHE9_MOUSE GGAVSAAMVKPHPTVQKQSSKQKKAIQTAIRKNKEANAVLARLNSELQQQLKEVHQERIA B1AV20_MOUSE B1AV20_MOUSE GGAVSAAMVKPHPTVQKQSSKQKKAIQTAIRKNKEANAVLARLNSELQQQLKEVHQERIA Q3UHF8_MOUSE Q3UHF8_MOUSE GGAVSAAMVKPHPTVQKQSSKQKKAIQTAIRKNKEANAVLARLNSELQQQLKEVHQERIA REPS2_MOUSE REPS2_MOUSE GGAVSAAMVKPHPTVQKQSSKQKKAIQTAIRKNKEANAVLARLNSELQQQLKEVHQERIA A2AFI8_MOUSE A2AFI8_MOUSE GGAVSAAMVKPHPTVQKQSSKQKKAIQTAIRKNKEANAVLARLNSELQQQLKEVHQERIA B9EI38_MOUSE B9EI38_MOUSE GGAVSAAMVKPHPTVQKQSSKQKKAIQTAIRKNKEANAVLARLNSELQQQLKEVHQERIA Q59H22_HUMAN Q59H22_HUMAN ---------------------------------------ICGIQPLISIELRAFRTSRHL B4DQQ8_HUMAN B4DQQ8_HUMAN SGPASAATMKPHPTVQKQSSKQKKAIQTAIRKNKEANAVLARLNSELQQQLKEVHQERIA A6PWZ6_HUMAN A6PWZ6_HUMAN SGPASAATMKPHPTVQKQSSKQKKAIQTAIRKNKEANAVLARLNSELQQQLKEVHQERIA REPS2_HUMAN REPS2_HUMAN SGPASAATMKPHPTVQKQSSKQKKAIQTAIRKNKEANAVLARLNSELQQQLKEVHQERIA Q5JNZ8_HUMAN Q5JNZ8_HUMAN SGPASAATMKPHPTVQKQSSKQKKAIQTAIRKNKEANAVLARLNSELQQQLKEVHQERIA MATCH CONSENSUS ????????????P???????K?KKAIQ??IR?NKE?N?VLARLNSELQQQLK?V??ERI?

Q5VSI7_DANRE Q5VSI7_DANRE LEVQLEQLRPFSHL----------------------------------- Q28CL0_XENTR Q28CL0_XENTR LEVQLEQLRPFSHL----------------------------------- Q5GMN1_XENLA Q5GMN1_XENLA LEVQLEQLRPFSHL----------------------------------- Q4S761_TETNG Q4S761_TETNG ------------------------------------------------- Q5ZK42_CHICK Q5ZK42_CHICK LEVQLEQLRPFSHLKPTAVNCEFTNFERGIGFKAYLKIHASSSVHSILH REPS1_MOUSE REPS1_MOUSE LEVQLEQLRPFSHL----------------------------------- A3KMX4_BOVIN A3KMX4_BOVIN LEVQLEQLRPFSHL----------------------------------- Q59GG6_HUMAN Q59GG6_HUMAN LEVQLEQLRPFSHL----------------------------------- B2R7D3_HUMAN B2R7D3_HUMAN LEVQLEQLRPFSHL----------------------------------- B7ZBZ8_HUMAN B7ZBZ8_HUMAN LEVQLEQLRPFSHL----------------------------------- REPS1_HUMAN REPS1_HUMAN LEVQLEQLRPFSHL----------------------------------- B7ZC00_HUMAN B7ZC00_HUMAN LEVQLEQLRPFSHL----------------------------------- B7ZBZ9_HUMAN B7ZBZ9_HUMAN LEVQLEQLRPFSHL----------------------------------- Q5JWJ8_HUMAN Q5JWJ8_HUMAN ------------------------------------------------- Q4SZC7_TETNG Q4SZC7_TETNG SAVDIRQQEGL-------------------------------------- Q5ZII0_CHICK Q5ZII0_CHICK LETQLEQLRPVTIL----------------------------------- Q3UHE9_MOUSE Q3UHE9_MOUSE LENQLEQLRPVTVL----------------------------------- B1AV20_MOUSE B1AV20_MOUSE LENQLEQLRPVTVL----------------------------------- Q3UHF8_MOUSE Q3UHF8_MOUSE LENQLEQLRPVTVL----------------------------------- REPS2_MOUSE REPS2_MOUSE LENQLEQLRPVTVL----------------------------------- A2AFI8_MOUSE A2AFI8_MOUSE LENQLEQLRPVTVL----------------------------------- B9EI38_MOUSE B9EI38_MOUSE LENQLEQLRPVTVL----------------------------------- Q59H22_HUMAN Q59H22_HUMAN FNVSLVHWQALSIA----------------------------------- B4DQQ8_HUMAN B4DQQ8_HUMAN LENQLEQLRPVTVL----------------------------------- A6PWZ6_HUMAN A6PWZ6_HUMAN LENQLEQLRPVTVL----------------------------------- REPS2_HUMAN REPS2_HUMAN LENQLEQLRPVTVL----------------------------------- Q5JNZ8_HUMAN Q5JNZ8_HUMAN LENQLEQLRPVTVL----------------------------------- MATCH CONSENSUS LE?QLEQLRP???L???????????????????????????????????


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