Alignment of the gene Family HBG057112 of HOVERGEN

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Isoforms are ON
B1H369_XENTR B1H369_XENTR ------------------------------------------------------------ Q6GPA7_XENLA Q6GPA7_XENLA ------------------------------------------------------------ Q0VCB2_BOVIN Q0VCB2_BOVIN -----------------------------------------------------MEESEEP A2AWU6_MOUSE A2AWU6_MOUSE -----------------------------------------------------MEMPEEP HDAC8_MOUSE HDAC8_MOUSE -----------------------------------------------------MEMPEEP B1WC68_RAT B1WC68_RAT -----------------------------------------------------MEIPEEP A6ND12_HUMAN A6ND12_HUMAN -----------------------------------------------------MEEPEEP A6NGT0_HUMAN A6NGT0_HUMAN -----------------------------------------------------MEEPEEP A6NMT1_HUMAN A6NMT1_HUMAN -----------------------------------------------------MEEPEEP B4DH31_HUMAN B4DH31_HUMAN -----------------------------------------------------MEEPEEP A6ND61_HUMAN A6ND61_HUMAN -----------------------------------------------------MEEPEEP A6NJR3_HUMAN A6NJR3_HUMAN -----------------------------------------------------MEEPEEP Q86VC8_HUMAN Q86VC8_HUMAN -----------------------------------------------------MEEPEEP A8MQ62_HUMAN A8MQ62_HUMAN -----------------------------------------------------MEEPEEP A6NGJ7_HUMAN A6NGJ7_HUMAN -----------------------------------------------------MEEPEEP B4DKN0_HUMAN B4DKN0_HUMAN -----------------------------------------------------MEEPEEP HDAC8_HUMAN HDAC8_HUMAN -----------------------------------------------------MEEPEEP Q4SY01_TETNG Q4SY01_TETNG ------------------------------------------------------------ Q7SXM0_DANRE Q7SXM0_DANRE ----------------------------------------------------MSEKSDSN HDAC3_XENLA HDAC3_XENLA ------------------------------------------------------------ HDAC3_XENTR HDAC3_XENTR ------------------------------------------------------------ HDAC3_CHICK HDAC3_CHICK ------------------------------------------------------------ Q9JM08_MOUSE Q9JM08_MOUSE ------------------------------------------------------------ Q9JLX5_MOUSE Q9JLX5_MOUSE ------------------------------------------------------------ HDAC3_PONAB HDAC3_PONAB ------------------------------------------------------------ HDAC3_HUMAN HDAC3_HUMAN ------------------------------------------------------------ HDAC3_MOUSE HDAC3_MOUSE ------------------------------------------------------------ HDAC3_RAT HDAC3_RAT ------------------------------------------------------------ Q3UM33_MOUSE Q3UM33_MOUSE ------------------------------------------------------------ B5X1R2_SALSA B5X1R2_SALSA ------------------------------------------------------------ HDAC3_DANRE HDAC3_DANRE ------------------------------------------------------------ HDAC3_TETNG HDAC3_TETNG ------------------------------------------------------------ B5X2P6_SALSA B5X2P6_SALSA --------------------------------------------------------MAYT Q59GB9_HUMAN Q59GB9_HUMAN ------------------------------------------------------------ B4DSK9_HUMAN B4DSK9_HUMAN ----------------------------------------------------------MA B7Z3S4_HUMAN B7Z3S4_HUMAN ------------------------------------------------------------ Q8BQ10_MOUSE Q8BQ10_MOUSE ---------------------------------------------------------MAY Q5R6R9_PONAB Q5R6R9_PONAB --------------------------------------------------------MAYS Q7SYZ5_XENLA Q7SYZ5_XENLA ---------------------------------------------------------MAY Q66J55_XENLA Q66J55_XENLA ---------------------------------------------------------MAY Q28CG8_XENTR Q28CG8_XENTR ---------------------------------------------------------MAY Q6GLI1_XENTR Q6GLI1_XENTR ---------------------------------------------------------MAY HDAC2_CHICK HDAC2_CHICK ---------------------------------------------------------MAY Q0VC01_BOVIN Q0VC01_BOVIN ---------------------------------------------------------MAY HDAC2_MOUSE HDAC2_MOUSE ---------------------------------------------------------MAY B1WBY8_RAT B1WBY8_RAT LRSRALPAPARRPAPGCPCCEGRRARRLPQPSCLAAGPRRARAAGGGAAARRRRPEPMAY HDAC2_HUMAN HDAC2_HUMAN ---------------------------------------------------------MAY B3KUJ5_HUMAN B3KUJ5_HUMAN ------------------------------------------------------------ B3KRS5_HUMAN B3KRS5_HUMAN ------------------------------------------------------------ Q3UXH8_MOUSE Q3UXH8_MOUSE ------------------------------------------------------------ Q5BL48_XENTR Q5BL48_XENTR ----------------------------------------------------------MA HDA1A_XENLA HDA1A_XENLA ----------------------------------------------------------MA HDA1B_XENLA HDA1B_XENLA ----------------------------------------------------------MA Q7ZYT5_XENLA Q7ZYT5_XENLA ----------------------------------------------------------MA Q4T0U0_TETNG Q4T0U0_TETNG --------------------------------------------------------MAYT Q4SIM2_TETNG Q4SIM2_TETNG ----------------------------------------------------------MA Q5RKQ4_DANRE Q5RKQ4_DANRE ---------------------------------------------------------MAL Q8JIY7_DANRE Q8JIY7_DANRE ---------------------------------------------------------MAL Q6P2A8_DANRE Q6P2A8_DANRE ---------------------------------------------------------MAL B5X2E0_SALSA B5X2E0_SALSA ---------------------------------------------------------MAL Q4RNX4_TETNG Q4RNX4_TETNG ---------------------------------------------------------MAL Q5HYD4_HUMAN Q5HYD4_HUMAN ------------------------------------------------------------ HDAC1_CHICK HDAC1_CHICK ----------------------------------------------------------MA B4DRG0_HUMAN B4DRG0_HUMAN ------------------------------------------------------------ HDAC1_RAT HDAC1_RAT ----------------------------------------------------------MA HDAC1_BOVIN HDAC1_BOVIN ----------------------------------------------------------MA HDAC1_MOUSE HDAC1_MOUSE ----------------------------------------------------------MA Q58E49_MOUSE Q58E49_MOUSE ----------------------------------------------------------MA Q99PA2_RAT Q99PA2_RAT ------------------------------------------------------------ Q5TEE2_HUMAN Q5TEE2_HUMAN ----------------------------------------------------------MA B5BU61_HUMAN B5BU61_HUMAN ----------------------------------------------------------MA HDAC1_HUMAN HDAC1_HUMAN ----------------------------------------------------------MA HDAC1_PONAB HDAC1_PONAB ----------------------------------------------------------MA Q6IT96_HUMAN Q6IT96_HUMAN ----------------------------------------------------------MA MATCH CONSENSUS ????????????????????????????????????????????????????????????

B1H369_XENTR B1H369_XENTR --MEESLLPVYIHSAE----YVELCDNVQSKVPRRASMVHSLIEAYGLLKEMRVVKPKVA Q6GPA7_XENLA Q6GPA7_XENLA --------------------------------------------------MSRVVKPKVA Q0VCB2_BOVIN Q0VCB2_BOVIN ADAGQSLPPVYIYSPE----YVSVCDSL-AKVPKRASMVHSLIEAYALHKQMRIVKPKVA A2AWU6_MOUSE A2AWU6_MOUSE ANSGHSLPPVYIYSPE----YVSICDSL-VKVPKRASMVHSLIEAYALHKQMRIVKPKVA HDAC8_MOUSE HDAC8_MOUSE ANSGHSLPPVYIYSPE----YVSICDSL-VKVPKRASMVHSLIEAYALHKQMRIVKPKVA B1WC68_RAT B1WC68_RAT ANSGHSLPPVYIYSPE----YVSICDSL-VKVPKRASMVHSLIEAYALHKQMRIVKPKVA A6ND12_HUMAN A6ND12_HUMAN ADSGQSLVPVYIYSPE----YVSMCDSL-AKIPKRASMVHSLIEAYALHKQMRIVKPKVA A6NGT0_HUMAN A6NGT0_HUMAN ADSGQSLVPVYIYSPE----YVSMCDSL-AKIPKRASMVHSLIEAYALHKQMRIVKPKVA A6NMT1_HUMAN A6NMT1_HUMAN ADSGQSLVPVYIYSPE----YVSMCDSL-AKIPKRASMVHSLIEAYALHKQMRIVKPKVA B4DH31_HUMAN B4DH31_HUMAN ADSGQSLVPVYIYSPE----YVSMCDSL-AKIPKRASMVHSLIEAYALHKQM-------- A6ND61_HUMAN A6ND61_HUMAN ADSGQSLVPVYIYSPE----YVSMCDSL-AKIPKRASMVHSLIEAYALHKQM-------- A6NJR3_HUMAN A6NJR3_HUMAN ADSGQSLVPVYIYSPE----YVSMCDSL-AKIPKRASMVHSLIEAYALHKQMRIVKPKVA Q86VC8_HUMAN Q86VC8_HUMAN ADSGQSLVPVYIYSPE----YVSMCDSP-AKIPKRASMVHSLIEAYALHKQMRIVKPKVA A8MQ62_HUMAN A8MQ62_HUMAN ADSGQSLVPVYIYSPE----YVSMCDSL-AKIPKRASMVHSLIEAYALHKQMRIVKPKVA A6NGJ7_HUMAN A6NGJ7_HUMAN ADSGQSLVPVYIYSPE----YVSMCDSL-AKIPKRASMVHSLIEAYALHKQM-------- B4DKN0_HUMAN B4DKN0_HUMAN ADSGQSLVPVYIYSPE----YVSMCDSL-AKIPKRASMVHSLIEAYALHKQM-------- HDAC8_HUMAN HDAC8_HUMAN ADSGQSLVPVYIYSPE----YVSMCDSL-AKIPKRASMVHSLIEAYALHKQMRIVKPKVA Q4SY01_TETNG Q4SY01_TETNG ---------------------------------MKNSPVSKAVVFFTLFS---VVKPELA Q7SXM0_DANRE Q7SXM0_DANRE DDKSRTRSVVYVYSPE----YIQTCDSL-SKVPNRASMVHSLIEAYGLLKYMRVVKPHVA HDAC3_XENLA HDAC3_XENLA ----MAKTVAYFYDPDVGNFHYGTGHPM---KPHRLSLTHSLVLHYGLYKKMIVFKPYQA HDAC3_XENTR HDAC3_XENTR ----MAKTVAYFYDPDVGNFHYGTGHPM---KPHRLSLTHSLVLHYGLYKKMIVFKPYQA HDAC3_CHICK HDAC3_CHICK ----MAKTVAYFYDPDVGNFHYGAGHPM---KPHRLALTHSLVLHYGLYKKMIVFKPYQA Q9JM08_MOUSE Q9JM08_MOUSE ----MAKTVAYFYDPDVGNFHYGAGHPM---KPHRLALTHSLVLHYGLYKKMIVFKPYQA Q9JLX5_MOUSE Q9JLX5_MOUSE ----MAKTVAYFYDPDVGNFHYGAGHPM---KPHRLALTHSLVLHYGLYKKMIVFKPYQA HDAC3_PONAB HDAC3_PONAB ----MAKTVAYFYDPDVGNFHYGAGHPM---KPHRLALTHSLVLHYGLYKKMIVFKPYQA HDAC3_HUMAN HDAC3_HUMAN ----MAKTVAYFYDPDVGNFHYGAGHPM---KPHRLALTHSLVLHYGLYKKMIVFKPYQA HDAC3_MOUSE HDAC3_MOUSE ----MAKTVAYFYDPDVGNFHYGAGHPM---KPHRLALTHSLVLHYGLYKKMIVFKPYQA HDAC3_RAT HDAC3_RAT ----MAKTVAYFYDPDVGNFHYGAGHPM---KPHRLALTHSLVLHYGLYKKMIVFKPYQA Q3UM33_MOUSE Q3UM33_MOUSE ----MAKTVAYFYDPDVGNFHYGAGHPM---KPHRLALTHSLVLHYGLYKKMIVFKPYQA B5X1R2_SALSA B5X1R2_SALSA ----MSNRTAYFYDPDVGNFHYGAGHPM---KPHRLSLTHSLVLHYGLYKKMQVFKPYKA HDAC3_DANRE HDAC3_DANRE ----MTNRTAYFYDPDVGNFHYGAGHPM---KPHRLSLTHSLVLHYGLYKKMMVFKPYKA HDAC3_TETNG HDAC3_TETNG ----MTNRTSYFYDPDVGNFHYGAGHPM---KPHRLSLTHSLVLHYGLYKKMMVFKPYKA B5X2P6_SALSA B5X2P6_SALSA VAGGTKKKVCYYYDGDIGNYYYGQGHPM---KPHRIRMTHNLLLNYGLYRKMEIYRPHKA Q59GB9_HUMAN Q59GB9_HUMAN -------------------------------------VTFALII---------------- B4DSK9_HUMAN B4DSK9_HUMAN QTQGTRRKVCYYYDGDVGNYYYGQGHPM---KPHRIRMTHNLLLNYGLYRKMEIYRPHKA B7Z3S4_HUMAN B7Z3S4_HUMAN ------------------------------------------------------------ Q8BQ10_MOUSE Q8BQ10_MOUSE SQGGGKKKVCYYYDGDIGNYYYGQGHPM---KPHRIRMTHNLLLNYGLYRKMEIYRPHKA Q5R6R9_PONAB Q5R6R9_PONAB -QGGGKKKVCYYYDGDIGNYYYGQGHPM---KPHRIRMTHNLLLNYGLYRKMEIYRPHKA Q7SYZ5_XENLA Q7SYZ5_XENLA TQGGAKKKVCYYYDGDIGNYYYGQGHPM---KPHRIRMTHNLLLNYGLYRKMEIYRPHKA Q66J55_XENLA Q66J55_XENLA TQGGAKKKVCYYYDGDIGNYYYGQGHPM---KPHRIRMTHNLLLNYGLYRKMEIYRPHKA Q28CG8_XENTR Q28CG8_XENTR TQGGAKKKVCYYYDGDIGNYYYGQGHPM---KPHRIRMTHNLLLNYGLYRKMEIYRPHKA Q6GLI1_XENTR Q6GLI1_XENTR TQGGAKKKVCYYYDGDIGNYYYGQGHPM---KPHRIRMTHNLLLNYGLYRKMEIYRPHKA HDAC2_CHICK HDAC2_CHICK SQGGGKKKVCYYYDGDIGNYYYGQGHPM---KPHRIRMTHNLLLNYGLYRKMEIYRPHKA Q0VC01_BOVIN Q0VC01_BOVIN SQGGGKKKVCYYYDGDIGNYYYGQGHPM---KPHRIRMTHNLLLNYGLYRKMEIYRPHKA HDAC2_MOUSE HDAC2_MOUSE SQGGGKKKVCYYYDGDIGNYYYGQGHPM---KPHRIRMTHNLLLNYGLYRKMEIYRPHKA B1WBY8_RAT B1WBY8_RAT SQGGGKKKVCYYYDGDIGNYYYGQGHPM---KPHRIRMTHNLLLNYGLYRKMEIYRPHKA HDAC2_HUMAN HDAC2_HUMAN SQGGGKKKVCYYYDGDIGNYYYGQGHPM---KPHRIRMTHNLLLNYGLYRKMEIYRPHKA B3KUJ5_HUMAN B3KUJ5_HUMAN ---------------------------M---KPHRIRMTHNLLLNHGLYRKMEIYRPHKA B3KRS5_HUMAN B3KRS5_HUMAN ---------------------------M---KPHRIRMTHNLLLNYGLYRKMEIYRPHKA Q3UXH8_MOUSE Q3UXH8_MOUSE ------------------------------------------------------------ Q5BL48_XENTR Q5BL48_XENTR LSQGTKKKVCYYYDGDVGNYYYGQGHPI---KPHRIRMTHNLLLNYGLYRKMEIYRPHKA HDA1A_XENLA HDA1A_XENLA LTLGTKKKVCYYYDGDVGNYYYGQGHPM---KPHRIRMTHNLLLNYGLYRKMEIFRPHKA HDA1B_XENLA HDA1B_XENLA LSQGTKKKVCYYYDGDVGNYYYGQGHPM---KPHRIRMTHNLLLNYGLYRKMEIYRPHKA Q7ZYT5_XENLA Q7ZYT5_XENLA LSQGTKKKVCYYYDGDVGNYYYGQGHPM---KPHRIRMTHNLLLNYGLYRKMEIYRPHKA Q4T0U0_TETNG Q4T0U0_TETNG TATGTKKKVCYYYDGDIGNYYYGQGHPM---KPHRIRMTHNLLLNYGLYRKMEIYRPHKA Q4SIM2_TETNG Q4SIM2_TETNG LSQGTKKKVCYYYDGDVGNYYYGQGHPM---KPHRIRMTHNLLLNYGLYRRMEIYRPHKA Q5RKQ4_DANRE Q5RKQ4_DANRE SSQGTKKKVCYYYDGDVGNYYYGQGHPM---KPHRIRMTHNLLLNYGLYRKMEIYRPHKA Q8JIY7_DANRE Q8JIY7_DANRE SSQGTKKKVCYYYDGDVGNYYYGQGHPM---KPHRIRMTHNLLLNYGLYRKMEIYRPHKA Q6P2A8_DANRE Q6P2A8_DANRE SSQGTKKKVCYYYDGDVGNYYYGQGHPM---KPHRIRMTHNLLLNYGLYRKMEIYRPHKA B5X2E0_SALSA B5X2E0_SALSA SSQGTKKKVCYYYDGDVGNYYYGQGHPM---KPHRIRMTHNLLLNYGLYRKMEIYRPHKA Q4RNX4_TETNG Q4RNX4_TETNG TSQGTKKKVCYYYDGDVGNYYYGQGHPM---KPHRIRMTHNLLLNYGLYRKMEIYRPHKA Q5HYD4_HUMAN Q5HYD4_HUMAN ------------------------------------------------------------ HDAC1_CHICK HDAC1_CHICK LTQGTKRKVCYYYDGDVGNYYYGQGHPM---KPHRIRMTHNLLLNYGLYRKMEIYRPHKA B4DRG0_HUMAN B4DRG0_HUMAN ------------------------------------------------------------ HDAC1_RAT HDAC1_RAT QTQGTKRKVCYYYDGDVGNYYYGQGHPM---KPHRIRMTHNLLLNYGLYRKMEIYRPHKA HDAC1_BOVIN HDAC1_BOVIN QTQGTKRKVCYYYDGDVGNYYYGQGHPM---KPHRIRMTHNLLLNYGLYRKMEIYRPHKA HDAC1_MOUSE HDAC1_MOUSE QTQGTKRKVCYYYDGDVGNYYYGQGHPM---KPHRIRMTHNLLLNYGLYRKMEIYRPHKA Q58E49_MOUSE Q58E49_MOUSE QTQGTKRKVCYYYDGDVGNYYYGQGHPM---KPHRIRMTHNLLLNYGLYRKMEIYRPHKA Q99PA2_RAT Q99PA2_RAT ------------------------------------------------------------ Q5TEE2_HUMAN Q5TEE2_HUMAN QTQGTRRKVCYYYDGDVGNYYYGQGHPM---KPHRIRMTHNLLLNYGLYRKMEIYRPHKA B5BU61_HUMAN B5BU61_HUMAN QTQGTRRKVCYYYDGDVGNYYYGQGHPM---KPHRIRMTHNLLLNYGLYRKMEIYRPHKA HDAC1_HUMAN HDAC1_HUMAN QTQGTRRKVCYYYDGDVGNYYYGQGHPM---KPHRIRMTHNLLLNYGLYRKMEIYRPHKA HDAC1_PONAB HDAC1_PONAB QTQGTRRKVCYYYDGDVGNYYYGQGHPM---KPHRIRMTHNLLLNYGLYRKMEIYRPHKA Q6IT96_HUMAN Q6IT96_HUMAN QTQGTRRKVCYYYDGDVGNYYYGQGHPM---KPHRIRMTHNLLLNYGLYRKMEIYRPHKA MATCH CONSENSUS ??????????Y?Y???????????????????P?R????H?L???Y?L???M????P??A

B1H369_XENTR B1H369_XENTR SMEEMAAFHTDSYLQHLHKVSEEGDNDDPETLE-YGLGYDCPITEGIYDYAAAVGGATLT Q6GPA7_XENLA Q6GPA7_XENLA SMEEMAAFHTDAYLQHLHKVSEEGDNDDPETLE-YGLGYDCPITEGIYDYAAAVGGATLT Q0VCB2_BOVIN Q0VCB2_BOVIN SMEEMASFHTDAYLQHLQKVSEDGDDDHPDSIE-YGLGYDCPATEGIFDYAAAVGGATIT A2AWU6_MOUSE A2AWU6_MOUSE SMEEMATFHTDAYLQHLQKVSQEGDEDHPDSIE-YGLGYDCPATEGIFDYAAAIGGGTIT HDAC8_MOUSE HDAC8_MOUSE SMEEMATFHTDAYLQHLQKVSQEGDEDHPDSIE-YGLGYDCPATEGIFDYAAAIGGGTIT B1WC68_RAT B1WC68_RAT SMEEMATFHTDAYLQHLQKVSQEGDEDHPDSIE-YGLGYDCPATEGIFDYAAAIGGGTIT A6ND12_HUMAN A6ND12_HUMAN SMEEMATFHTDAYLQHLQKVSQEGDDDHPDSIE-YGLGYDCPATEGIFDYAAAIGGATIT A6NGT0_HUMAN A6NGT0_HUMAN SMEEMATFHTDAYLQHLQKVSQEGDDDHPDSIE-YGLGYDCPATEGIFDYAAAIGGATIT A6NMT1_HUMAN A6NMT1_HUMAN SMEEMATFHTDAYLQHLQKVSQEGDDDHPDSIE-YGLGYDCPATEGIFDYAAAIGGATIT B4DH31_HUMAN B4DH31_HUMAN ------------------------------------------------------------ A6ND61_HUMAN A6ND61_HUMAN ------------------------------------------------------------ A6NJR3_HUMAN A6NJR3_HUMAN SMEEMATFHTDAYLQHLQKVSQEGDDDHPDSIE-YGLGYDCPATEGIFDYAAAIGGATIT Q86VC8_HUMAN Q86VC8_HUMAN SMEEMATFHTDAYLQHLQKVSQEGDDDHPDSIE-YGLGYDCPATEGIFDYAAAIGGATIT A8MQ62_HUMAN A8MQ62_HUMAN SMEEMATFHTDAYLQHLQKVSQEGDDDHPDSIE-YGLGYDCPATEGIFDYAAAIGGATIT A6NGJ7_HUMAN A6NGJ7_HUMAN ------------------------------------------------------------ B4DKN0_HUMAN B4DKN0_HUMAN ------------------------------------------------------------ HDAC8_HUMAN HDAC8_HUMAN SMEEMATFHTDAYLQHLQKVSQEGDDDHPDSIE-YGLGYDCPATEGIFDYAAAIGGATIT Q4SY01_TETNG Q4SY01_TETNG TIEQMAKFHTDSYLEHLHKISQDGDNDDPQSGD-YGLGYDCPVVEGIFDYAAAVGGATLT Q7SXM0_DANRE Q7SXM0_DANRE SIEEMAVFHTDSYLQHLHKISQDGDNDDPQSAD-FGLGYDCPVVEGIFDYAAAVGGATLT HDAC3_XENLA HDAC3_XENLA SQHDMCRFHSEDYIDFLQRVSPNNMQGFTKSLNAFNVGDDCPVFPGLFEFCSRYTGASLQ HDAC3_XENTR HDAC3_XENTR SQHDMCRFHSEDYIDFLQRVSPNNMQGFTKSLNAFNVGDDCPVFPGLFEFCSRYTGASLQ HDAC3_CHICK HDAC3_CHICK SQHDMCRFHSEDYIDFLQRVSPNNMQGFTKSLNAFNVGDDCPVFPGLFEFCSRYTGASLQ Q9JM08_MOUSE Q9JM08_MOUSE SQHDMCRFHSEDYIDFLQRVSPTNMQGFTKSLDAFNVGDDCPVFPGLFEFCSRYTGASLQ Q9JLX5_MOUSE Q9JLX5_MOUSE SQHDMCRFHSEDYIDFLQRVSPTNMQGFTKSLNAFNVGDDCPVFPGLFEFCSRYTGASLQ HDAC3_PONAB HDAC3_PONAB SQHDMCRFHSEDYIDFLQRVSPTNMQGFTKSLNAFNVGDDCPVFPGLFEFCSRYTGASLQ HDAC3_HUMAN HDAC3_HUMAN SQHDMCRFHSEDYIDFLQRVSPTNMQGFTKSLNAFNVGDDCPVFPGLFEFCSRYTGASLQ HDAC3_MOUSE HDAC3_MOUSE SQHDMCRFHSEDYIDFLQRVSPTNMQGFTKSLNAFNVGDDCPVFPGLFEFCSRYTGASLQ HDAC3_RAT HDAC3_RAT SQHDMCRFHSEDYIDFLQRVSPTNMQGFTKSLNAFNVGDDCPVFPGLFEFCSRYTGASLQ Q3UM33_MOUSE Q3UM33_MOUSE SQHDMCRFHSEDYIDFLQRVSPTNMQGFTKSLNAFNVGDDCPVFPGLFEFCSRYTGASLQ B5X1R2_SALSA B5X1R2_SALSA SQHDMCRFHSEDYIDFLQKVSPNNMQGFTKSLNTFNVGDDCPVFPGLFEFCSRYTGASLQ HDAC3_DANRE HDAC3_DANRE SQHDMCRFHSEDYIDFLQKVSPNNMQGFTKSLNTFNVGGDCPVFPGLFEFCSRYTGASLQ HDAC3_TETNG HDAC3_TETNG SQHDMCRFHSEDYIDFLQKVSPNNMQGFTKSLNTFNVGDDCPVFPGLFEFCSRYTGASLQ B5X2P6_SALSA B5X2P6_SALSA TAEEITKYHSDDYIQFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSAA Q59GB9_HUMAN Q59GB9_HUMAN ------------FLKFI-----------------FRTVAVC-------RFC--------- B4DSK9_HUMAN B4DSK9_HUMAN NAEEMTKYHSDDYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVA B7Z3S4_HUMAN B7Z3S4_HUMAN ----MTKYHSDDYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVA Q8BQ10_MOUSE Q8BQ10_MOUSE TAEEMTKYHSDEYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVA Q5R6R9_PONAB Q5R6R9_PONAB TAEEMTKYHSDEYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVA Q7SYZ5_XENLA Q7SYZ5_XENLA TAEEMTKYHSDEYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVA Q66J55_XENLA Q66J55_XENLA TAEEMTKYHSDEYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVA Q28CG8_XENTR Q28CG8_XENTR TAEEMTKYHSDEYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVA Q6GLI1_XENTR Q6GLI1_XENTR TAEEMTKYHSDEYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVA HDAC2_CHICK HDAC2_CHICK TAEEMTKYHSDEYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVA Q0VC01_BOVIN Q0VC01_BOVIN TAEEMTKYHSDEYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVA HDAC2_MOUSE HDAC2_MOUSE TAEEMTKYHSDEYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVA B1WBY8_RAT B1WBY8_RAT TAEEMTKYHSDEYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVA HDAC2_HUMAN HDAC2_HUMAN TAEEMTKYHSDEYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVA B3KUJ5_HUMAN B3KUJ5_HUMAN TAEEMTKYHSDEYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVA B3KRS5_HUMAN B3KRS5_HUMAN TAEEMTKYHSDEYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVA Q3UXH8_MOUSE Q3UXH8_MOUSE ------------------------------------------------------------ Q5BL48_XENTR Q5BL48_XENTR SAEEMTKYHSDDYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVA HDA1A_XENLA HDA1A_XENLA SAEDMTKYHSDDYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSAGGSVA HDA1B_XENLA HDA1B_XENLA SAEEMTKYHSDDYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVA Q7ZYT5_XENLA Q7ZYT5_XENLA SAEEMTKYHSDDYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVA Q4T0U0_TETNG Q4T0U0_TETNG TAEEMTKYHSDDYIKFLRSIRPDNMSEFSKQMQRFNVGEDCPVFDGLFEFCQLSAGGSAA Q4SIM2_TETNG Q4SIM2_TETNG SGEEMTKYHSDDYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVA Q5RKQ4_DANRE Q5RKQ4_DANRE NAEEMTKYHSDDYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSAGGSVA Q8JIY7_DANRE Q8JIY7_DANRE NAEEMTKYHSDDYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVA Q6P2A8_DANRE Q6P2A8_DANRE NAEEMTKYHSDDYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVA B5X2E0_SALSA B5X2E0_SALSA NGEEMTKYHSDDYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVA Q4RNX4_TETNG Q4RNX4_TETNG NGEEMTKYHSDDYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSVGGSVA Q5HYD4_HUMAN Q5HYD4_HUMAN ------------------------------------------------------------ HDAC1_CHICK HDAC1_CHICK NAEEMTKYHSDDYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSAGGSVA B4DRG0_HUMAN B4DRG0_HUMAN ------------------------------------------------------------ HDAC1_RAT HDAC1_RAT NAEEMTKYHSDDYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVA HDAC1_BOVIN HDAC1_BOVIN NAEEMTKYHSDDYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVA HDAC1_MOUSE HDAC1_MOUSE NAEEMTKYHSDDYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVA Q58E49_MOUSE Q58E49_MOUSE NAEEMTKYHSDDYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVA Q99PA2_RAT Q99PA2_RAT ------------------------------------------------------------ Q5TEE2_HUMAN Q5TEE2_HUMAN NAEEMTKYHSDDYIKFLRSIRPDNMSEYSKQMQR-------------------------S B5BU61_HUMAN B5BU61_HUMAN NAEEMTKYHSDDYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVA HDAC1_HUMAN HDAC1_HUMAN NAEEMTKYHSDDYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVA HDAC1_PONAB HDAC1_PONAB NAEEMTKYHSDDYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVA Q6IT96_HUMAN Q6IT96_HUMAN NAEEMTKYHSDDYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVA MATCH CONSENSUS ????M???H???Y???L????????????????????G?DCP???G?F???????G????

B1H369_XENTR B1H369_XENTR AAEQLMAGKTRIAINWPGGWHHAKKDEASGFCYLNDAVLGILKLREKFDRVLYVDMDLHH Q6GPA7_XENLA Q6GPA7_XENLA AAEQLIEGKTRIAVNWPGGWHHAKKDEASGFCYLNDAVLGILKLREKFDRVLYVDMDLHH Q0VCB2_BOVIN Q0VCB2_BOVIN AAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFDRILYVDLDLHH A2AWU6_MOUSE A2AWU6_MOUSE AAQCLIDGKCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFDRILYVDLDLHH HDAC8_MOUSE HDAC8_MOUSE AAQCLIDGKCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFDRILYVDLDLHH B1WC68_RAT B1WC68_RAT AAQCLIDGKCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFDRILYVDLDLHH A6ND12_HUMAN A6ND12_HUMAN AAQCLIDGMCKVAINWSGGWHHAKKE---------------------------------- A6NGT0_HUMAN A6NGT0_HUMAN AAQCLIDGMCKVAINWSGGWHHAKKYEPP------------------------------- A6NMT1_HUMAN A6NMT1_HUMAN AAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLHH B4DH31_HUMAN B4DH31_HUMAN ------------------------RDEASGFCYLNDAVLGILRLRRKFERILYVDLDLHH A6ND61_HUMAN A6ND61_HUMAN ------------------------RDEASGFCYLNDAVLGILRLRRKFERILYVDLDLHH A6NJR3_HUMAN A6NJR3_HUMAN AAQCLIDGMCKVAINWSGGWHHAKK----------------------------------- Q86VC8_HUMAN Q86VC8_HUMAN AAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLHH A8MQ62_HUMAN A8MQ62_HUMAN AAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLHH A6NGJ7_HUMAN A6NGJ7_HUMAN ------------------------RDEASGFCYLNDAVLGILRLRRKFERILYVDLDLHH B4DKN0_HUMAN B4DKN0_HUMAN ------------------------RDEASGFCYLNDAVLGILRLRRKFERILYVDLDLHH HDAC8_HUMAN HDAC8_HUMAN AAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLHH Q4SY01_TETNG Q4SY01_TETNG AAQCLLDQKCDVAINWAGGWHHAKKDEASGFCYVNDAVLGILRLRERYERVLYVDVDLHH Q7SXM0_DANRE Q7SXM0_DANRE AAQNLLDGKCDVAINWAGGWHHAKKDEASGSCYVNDAVLGILKLREKYDRVLYVDVDLHH HDAC3_XENLA HDAC3_XENLA GATLLNNKNCDIAINWAGGLHHAKKFEASGFCYVNDIVIGILELLKYHPRVLYIDIDIHH HDAC3_XENTR HDAC3_XENTR GATQLNNKICDIAINWAGGLHHAKKFEASGFCYVNDIVIGILELLKYHPRVLYVDIDIHH HDAC3_CHICK HDAC3_CHICK GATQLNNKICDIAINWAGGLHHAKKFEASGFCYVNDIVIGILELLKYHPRVLYIDIDIHH Q9JM08_MOUSE Q9JM08_MOUSE GATQLNNKICDIAINWARGLHHAKKFEASGFCYVNDIVIGILELLKYHPRVLYIDIDIHH Q9JLX5_MOUSE Q9JLX5_MOUSE GATQLNNKICDIAINWAGGLHHAKKFEASGFCYVNDIVIGILEPLKYHPRVLYIDIDIHH HDAC3_PONAB HDAC3_PONAB GATQLNNKICDIAINWAGGLHHAKKFEASGFCYVNDIVIGILELLKYHPRVLYIDIDIHH HDAC3_HUMAN HDAC3_HUMAN GATQLNNKICDIAINWAGGLHHAKKFEASGFCYVNDIVIGILELLKYHPRVLYIDIDIHH HDAC3_MOUSE HDAC3_MOUSE GATQLNNKICDIAINWAGGLHHAKKFEASGFCYVNDIVIGILELLKYHPRVLYIDIDIHH HDAC3_RAT HDAC3_RAT GATQLNNKICDIAINWAGGLHHAKKFEASGFCYVNDIVIGILELLKYHPRVLYIDIDIHH Q3UM33_MOUSE Q3UM33_MOUSE GATQLNNKICDIAINWAGGLHHAKKFEASGFCYVNDIVIGILELLKYHPRVLYIDIDIHH B5X1R2_SALSA B5X1R2_SALSA GATQLNHKICDIAINWAGGLHHAKKFEASGFCYVNDIVISILELLKYHPRVLYIDIDIHH HDAC3_DANRE HDAC3_DANRE GATQLNHKICDIAINWAGGLHHAKKFEASGFCYVNDIVISILELLKYHPRVLYIDIDIHH HDAC3_TETNG HDAC3_TETNG GATQLNHKICDIAINWAGGLHHAKKFEASGFCYVNDIVISILELLKYHPRVLYIDIDIHH B5X2P6_SALSA B5X2P6_SALSA GSVKLNRQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHH Q59GB9_HUMAN Q59GB9_HUMAN -------------------------------CYPNLLVL--------------------- B4DSK9_HUMAN B4DSK9_HUMAN SAVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHH B7Z3S4_HUMAN B7Z3S4_HUMAN SAVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHH Q8BQ10_MOUSE Q8BQ10_MOUSE GAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHH Q5R6R9_PONAB Q5R6R9_PONAB GAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHH Q7SYZ5_XENLA Q7SYZ5_XENLA GAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLGILELLKYHQRVLYIDIDIHH Q66J55_XENLA Q66J55_XENLA GAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLGILELLKYHQRVLYIDIDIHH Q28CG8_XENTR Q28CG8_XENTR GAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHH Q6GLI1_XENTR Q6GLI1_XENTR GAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHH HDAC2_CHICK HDAC2_CHICK GAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHH Q0VC01_BOVIN Q0VC01_BOVIN GAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHH HDAC2_MOUSE HDAC2_MOUSE GAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHH B1WBY8_RAT B1WBY8_RAT GAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAVLELLKYHQRVLYIDIDIHH HDAC2_HUMAN HDAC2_HUMAN GAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHH B3KUJ5_HUMAN B3KUJ5_HUMAN GAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHH B3KRS5_HUMAN B3KRS5_HUMAN GAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHH Q3UXH8_MOUSE Q3UXH8_MOUSE ------------------------------------------KLLKYHQRVLYIDIDIHH Q5BL48_XENTR Q5BL48_XENTR SSVKLNKQQTDISVNWSGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHH HDA1A_XENLA HDA1A_XENLA SAVKLNKQQTDISVNWSGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVVYIDIDIHH HDA1B_XENLA HDA1B_XENLA SAVKLNKQQTDISVNWSGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVVYIDIDIHH Q7ZYT5_XENLA Q7ZYT5_XENLA SAVKLNKQQTDISVNWSGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVVYIDIDIHH Q4T0U0_TETNG Q4T0U0_TETNG GSVKLNRQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHH Q4SIM2_TETNG Q4SIM2_TETNG GAVKLNKQQTDIAINWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHH Q5RKQ4_DANRE Q5RKQ4_DANRE GAVKLNKQQTDIAINWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHH Q8JIY7_DANRE Q8JIY7_DANRE GAVKLNKQQTDIAINWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHH Q6P2A8_DANRE Q6P2A8_DANRE GAVKLNKQQTDIAINWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHH B5X2E0_SALSA B5X2E0_SALSA GAVKLNKQQTDIAINWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHH Q4RNX4_TETNG Q4RNX4_TETNG GAVKLNKQQTDIAINWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHH Q5HYD4_HUMAN Q5HYD4_HUMAN ------------------------------------------------------------ HDAC1_CHICK HDAC1_CHICK SAVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHH B4DRG0_HUMAN B4DRG0_HUMAN ------------------------------------------------------------ HDAC1_RAT HDAC1_RAT SAVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHH HDAC1_BOVIN HDAC1_BOVIN SAVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHH HDAC1_MOUSE HDAC1_MOUSE SAVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHH Q58E49_MOUSE Q58E49_MOUSE SAVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHH Q99PA2_RAT Q99PA2_RAT ------------------------------------------------------------ Q5TEE2_HUMAN Q5TEE2_HUMAN SAVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHH B5BU61_HUMAN B5BU61_HUMAN SAVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHH HDAC1_HUMAN HDAC1_HUMAN SAVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHH HDAC1_PONAB HDAC1_PONAB SAVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHH Q6IT96_HUMAN Q6IT96_HUMAN SAVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHH MATCH CONSENSUS ?A??L???????A?NW?GG?HHAKK?EASGFCY?ND?V??IL?L?????R?LY?D?D?HH

B1H369_XENTR B1H369_XENTR GDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDIGLGKGRYYSVNVPLQDGIQDEKYY Q6GPA7_XENLA Q6GPA7_XENLA GDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDIGLGKGRYYSINVPLQDGIQDDKYY Q0VCB2_BOVIN Q0VCB2_BOVIN GDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDCIQDERYY A2AWU6_MOUSE A2AWU6_MOUSE GDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDMSDVGLGKGRYYSVNVPIQDGIQDEKYY HDAC8_MOUSE HDAC8_MOUSE GDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDMSDVGLGKGRYYSVNVPIQDGIQDEKYY B1WC68_RAT B1WC68_RAT GDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDMSDVGLGKGRYYSVNVPIQDGIQDEKYY A6ND12_HUMAN A6ND12_HUMAN ------------------------------------------------------------ A6NGT0_HUMAN A6NGT0_HUMAN --------------------------APNPG----------------------------- A6NMT1_HUMAN A6NMT1_HUMAN GDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKYY B4DH31_HUMAN B4DH31_HUMAN GDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKYY A6ND61_HUMAN A6ND61_HUMAN GD--------------------------GTGDVSDVGLGKGRYYSVNVPIQDGIQDEKYY A6NJR3_HUMAN A6NJR3_HUMAN ------------------------------------------------------------ Q86VC8_HUMAN Q86VC8_HUMAN GDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKYY A8MQ62_HUMAN A8MQ62_HUMAN GDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKYY A6NGJ7_HUMAN A6NGJ7_HUMAN GDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKYY B4DKN0_HUMAN B4DKN0_HUMAN GDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKYY HDAC8_HUMAN HDAC8_HUMAN GDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKYY Q4SY01_TETNG Q4SY01_TETNG GDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDLCDTGLGKGRWYAVNVPLEDGIKDDRYY Q7SXM0_DANRE Q7SXM0_DANRE GDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVTDTGLGKGRWYAVNVPFEDGVRDDRYC HDAC3_XENLA HDAC3_XENLA GDGVQEAFYLTDRVMTVSFHKYGNYFFPGTGDMYEVGAESGRYYCLNVPLRDGIDDQSYR HDAC3_XENTR HDAC3_XENTR GDGVQEAFYLTDRVMTVSFHKYGNYFFPGTGDMYEVGAESGRYYCLNVPLRDGIDDQSYR HDAC3_CHICK HDAC3_CHICK GDGVQEAFYLTDRVMTVSFHKYGNYFFPGTGDMYEVGAESGRYYALNVPLRDGIDDQSYK Q9JM08_MOUSE Q9JM08_MOUSE GDGVQEAFYLTDRVMTVSFHKYGNYFFPGAGDMYEVGAESGRYYCLNVPLRDGIDDQSYK Q9JLX5_MOUSE Q9JLX5_MOUSE GDGVQEAFYLTDRVMTVSFHKYGNYFFPGTGDMYEVGAESGRYYCLNVPLRDGIDDQSYK HDAC3_PONAB HDAC3_PONAB GDGVQEAFYLTDRVMTVSFHKYGNYFFPGTGDMYEVGAESGRYYCLNVPLRDGIDDQSYK HDAC3_HUMAN HDAC3_HUMAN GDGVQEAFYLTDRVMTVSFHKYGNYFFPGTGDMYEVGAESGRYYCLNVPLRDGIDDQSYK HDAC3_MOUSE HDAC3_MOUSE GDGVQEAFYLTDRVMTVSFHKYGNYFFPGTGDMYEVGAESGRYYCLNVPLRDGIDDQSYK HDAC3_RAT HDAC3_RAT GDGVQEAFYLTDRVMTVSFHKYGNYFFPGTGDMYEVGAESGRYYCLNVPLRDGIDDQSYK Q3UM33_MOUSE Q3UM33_MOUSE GDGVQEAFYLTDRVMTVSFHKYGNYFFPGTGDMYEVGAESGRYYCLNVPLRDGIDDQSYK B5X1R2_SALSA B5X1R2_SALSA GDGVQEAFYLTDRVMTVSFHKYGNYFFPGTGDMYEVGAESGRYYCLNVPLRDGIDDQSYR HDAC3_DANRE HDAC3_DANRE GDGVQEAFYLTDRVMTVSFHKYGNYFFPGTGDMYEVGAESGRYYCLNVPLRDGIDDQSYR HDAC3_TETNG HDAC3_TETNG GDGVQEAFYLTDRVMTVSFHKYGNYFFPGTGDMYEVGAESGRYYCLNVPLRDGIDDQSYR B5X2P6_SALSA B5X2P6_SALSA GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNFPLRDGVDDESYE Q59GB9_HUMAN Q59GB9_HUMAN ------------------------------------------------------------ B4DSK9_HUMAN B4DSK9_HUMAN GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLR-----------VRTPFR---SQPAYP B7Z3S4_HUMAN B7Z3S4_HUMAN GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLR-----------VRTPFR---SQPAYP Q8BQ10_MOUSE Q8BQ10_MOUSE GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYG Q5R6R9_PONAB Q5R6R9_PONAB GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLR-------------------------- Q7SYZ5_XENLA Q7SYZ5_XENLA GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYG Q66J55_XENLA Q66J55_XENLA GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYG Q28CG8_XENTR Q28CG8_XENTR GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYG Q6GLI1_XENTR Q6GLI1_XENTR GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYG HDAC2_CHICK HDAC2_CHICK GDGVEEAFYTTDRVMTVSEVSMVNN-FPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYG Q0VC01_BOVIN Q0VC01_BOVIN GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYG HDAC2_MOUSE HDAC2_MOUSE GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYG B1WBY8_RAT B1WBY8_RAT GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYG HDAC2_HUMAN HDAC2_HUMAN GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYG B3KUJ5_HUMAN B3KUJ5_HUMAN GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYG B3KRS5_HUMAN B3KRS5_HUMAN GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYG Q3UXH8_MOUSE Q3UXH8_MOUSE GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYG Q5BL48_XENTR Q5BL48_XENTR GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYE HDA1A_XENLA HDA1A_XENLA GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNYALRDGIDDESYE HDA1B_XENLA HDA1B_XENLA GDGVEEAFYTTDRVMSVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYE Q7ZYT5_XENLA Q7ZYT5_XENLA GDGVEEAFYTTDRVMSVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYE Q4T0U0_TETNG Q4T0U0_TETNG GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNFPLRDGIDDESYE Q4SIM2_TETNG Q4SIM2_TETNG GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYE Q5RKQ4_DANRE Q5RKQ4_DANRE GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYE Q8JIY7_DANRE Q8JIY7_DANRE GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYE Q6P2A8_DANRE Q6P2A8_DANRE GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYE B5X2E0_SALSA B5X2E0_SALSA GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYE Q4RNX4_TETNG Q4RNX4_TETNG GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYE Q5HYD4_HUMAN Q5HYD4_HUMAN ------------------------------------------------------------ HDAC1_CHICK HDAC1_CHICK GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYE B4DRG0_HUMAN B4DRG0_HUMAN --------------MTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYE HDAC1_RAT HDAC1_RAT GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYE HDAC1_BOVIN HDAC1_BOVIN GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYE HDAC1_MOUSE HDAC1_MOUSE GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYE Q58E49_MOUSE Q58E49_MOUSE GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYE Q99PA2_RAT Q99PA2_RAT ----------------------------------------------NYPLRDGIDDESYE Q5TEE2_HUMAN Q5TEE2_HUMAN GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNYPLRDGIDDES-- B5BU61_HUMAN B5BU61_HUMAN GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYE HDAC1_HUMAN HDAC1_HUMAN GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYE HDAC1_PONAB HDAC1_PONAB GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYE Q6IT96_HUMAN Q6IT96_HUMAN GDGVEEAFYTTDRVMTVSFHKYGEY-FPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYE MATCH CONSENSUS GDGV??AF??T??VMTVS?HK?????FPGTGD????G???G?YY??N?P??DGI?D??Y?

B1H369_XENTR B1H369_XENTR QICEGVLKEVFTTFNP-----------EAVVLQLG-----ADTIAGDPMCSFNMTPQGIG Q6GPA7_XENLA Q6GPA7_XENLA QICEGVLKEVFTTFNP-----------EAVVLQLG-----ADTIAGDPMCSFNMTPEGIG Q0VCB2_BOVIN Q0VCB2_BOVIN HICESVLKEVYIAFNP-----------KAVVLQLG-----ADTIAGDPMCSFNMTPVGIG A2AWU6_MOUSE A2AWU6_MOUSE HICESVLKEVYQAFNP-----------KAVVLQLG-----ADTIAGDPMCSFNMTPVGIG HDAC8_MOUSE HDAC8_MOUSE HICESVLKEVYQAFNP-----------KAVVLQLG-----ADTIAGDPMCSFNMTPVGIG B1WC68_RAT B1WC68_RAT HICESVLKEVYQAFNP-----------KAVVLQLG-----ADTIAGDPMCSFNMTPVGIG A6ND12_HUMAN A6ND12_HUMAN ---------------------------TCV------------------------------ A6NGT0_HUMAN A6NGT0_HUMAN ------------------------------------------------------------ A6NMT1_HUMAN A6NMT1_HUMAN QICE-------------------------------------------------------- B4DH31_HUMAN B4DH31_HUMAN QICESVLKEVYQAFNP-----------KAVVLQLG-----ADTIAGDPMCSFNMTPVGIG A6ND61_HUMAN A6ND61_HUMAN QI---------------------------------------------------------- A6NJR3_HUMAN A6NJR3_HUMAN ------------------------------------------------------------ Q86VC8_HUMAN Q86VC8_HUMAN QICESVLKEVYQAFNP-----------KAVVLQLG-----ADTIAGDPMCSFNMTPVGIG A8MQ62_HUMAN A8MQ62_HUMAN QICESVLKEVYQAFNP-----------KAVVLQLG-----ADTIAGDPMCSFNMTPVGIG A6NGJ7_HUMAN A6NGJ7_HUMAN QICESVLKEVYQAFNP-----------KAVVLQLG-----ADTIAGDPMCSFNMTPVGIG B4DKN0_HUMAN B4DKN0_HUMAN QICESVLKEVYQAFNP-----------KAVVLQLG-----ADTIAGDPMCSFNMTPVGIG HDAC8_HUMAN HDAC8_HUMAN QICESVLKEVYQAFNP-----------KAVVLQLG-----ADTIAGDPMCSFNMTPVGIG Q4SY01_TETNG Q4SY01_TETNG QIFTSVMQEVYAHFSP-----------EAVVMQLG-----ADTMAGDPMCSFNMTPVGVG Q7SXM0_DANRE Q7SXM0_DANRE QTFTSVMQEVKALFNP-----------EAVVMQLG-----ADTMAGDPMCSFNMTPVGVA HDAC3_XENLA HDAC3_XENLA HLFQPVIKQVIDFYQP-----------TCIVLQCG-----ADSLGCDRLGCFNLSIRGHG HDAC3_XENTR HDAC3_XENTR HLFQPVIKQVIDFYQP-----------TCIVLQCG-----ADSLGCDRLGCFNLSIRGHG HDAC3_CHICK HDAC3_CHICK HLFQPVINQVVDYYQP-----------TCIVLQCG-----ADSLGRDRLGCFNLSIRGHG Q9JM08_MOUSE Q9JM08_MOUSE HLFQPVISQVVDFYQP-----------TCIVLQCG-----ADSLGCDRLGCFNLSIRGHG Q9JLX5_MOUSE Q9JLX5_MOUSE HLFQPVISQVVDFYQP-----------TCIVLQCG-----ADSLGCDRLGCFNLSIRGHG HDAC3_PONAB HDAC3_PONAB HLFQPVINQVVDFYQP-----------TCIVLQCG-----ADSLGCDRLGCFNLSIRGHG HDAC3_HUMAN HDAC3_HUMAN HLFQPVINQVVDFYQP-----------TCIVLQCG-----ADSLGCDRLGCFNLSIRGHG HDAC3_MOUSE HDAC3_MOUSE HLFQPVISQVVDFYQP-----------TCIVLQCG-----ADSLGCDRLGCFNLSIRGHG HDAC3_RAT HDAC3_RAT HLFQPVISQVVDFYQP-----------TCIVLQCG-----ADSLGCDRLGCFNLSIRGHG Q3UM33_MOUSE Q3UM33_MOUSE HLFQPVISQVVDFYQP-----------TCIVLQCG-----ADSLGCDRLGCFNLSIRGHG B5X1R2_SALSA B5X1R2_SALSA QLFQPVIKQVVDFYQP-----------TCIVLQCG-----ADSLGCDRLGCFNLSIRGHG HDAC3_DANRE HDAC3_DANRE QLFQPVIKQVVDFYQP-----------TCIVLQCG-----ADSLGCDRLGCFNLSIRGHG HDAC3_TETNG HDAC3_TETNG QLFQPVIKQVVDFYQP-----------TCIVLQCG-----ADSLGCDRLGCFNLSIRGHG B5X2P6_SALSA B5X2P6_SALSA LIFKPVMAKVMEMYQP-----------SAVVLQCG-----ADSLSGDRLGCFNLTIRGHA Q59GB9_HUMAN Q59GB9_HUMAN ---------------------------------------------------------GHA B4DSK9_HUMAN B4DSK9_HUMAN QL-------------------------AALLL--------------SPISCH-------- B7Z3S4_HUMAN B7Z3S4_HUMAN QLAALLLSPI---------------------------------------SCH-------- Q8BQ10_MOUSE Q8BQ10_MOUSE QIFKPIISKVMEMYQP-----------SAVVLQCG-----ADSLSGDRLGCFNLTVKG-- Q5R6R9_PONAB Q5R6R9_PONAB ----------------------------------------------VRLNSV-------- Q7SYZ5_XENLA Q7SYZ5_XENLA QIFKPIISKVMEMYQP-----------SAVVLQCG-----PDSLSGDRLGCFNLTVKGHA Q66J55_XENLA Q66J55_XENLA QIFKPIISKVMEMYQP-----------SAVVLQCG-----ADSLSGDRLGCFNLTVKGHA Q28CG8_XENTR Q28CG8_XENTR QIFKPIISKVMEMYQP-----------SAVVLQCG-----ADSLSGDRLGCFNLTVKGHA Q6GLI1_XENTR Q6GLI1_XENTR QIFKPIISKVMEMYQP-----------SAVVLQCG-----ADSLSGDRLGCFNLTVKGHA HDAC2_CHICK HDAC2_CHICK QIFKPIISKVMEMYQP-----------SAVVLQCG-----ADSLSGDRLGCFNLTVKGHA Q0VC01_BOVIN Q0VC01_BOVIN QIFKPIISKVMEMYQP-----------SAVVLQCG-----ADSLSGDRLGCFNLTVKGHA HDAC2_MOUSE HDAC2_MOUSE QIFKPIISKVMEMYQP-----------SAVVLQCG-----ADSLSGDRLGCFNLTVKGHA B1WBY8_RAT B1WBY8_RAT QIFKPIISKVMEMYQP-----------SAVVLQCG-----ADSLSGDRLGCFNLTVKGHA HDAC2_HUMAN HDAC2_HUMAN QIFKPIISKVMEMYQP-----------SAVVLQCG-----ADSLSGDRLGCFNLTVKGHA B3KUJ5_HUMAN B3KUJ5_HUMAN QIFKPIISKVMEMYQP-----------SAVVLQCG-----ADSLSGDRLGCFNLTVKGHA B3KRS5_HUMAN B3KRS5_HUMAN QIFKPIISKVMEMYQP-----------SAVVLQCG-----ADSLSGDRLGCFNLTVKGHA Q3UXH8_MOUSE Q3UXH8_MOUSE QIFKPIISKVMEMYQP-----------SAVVLQCG-----ADSLSGDRLGCFNLTVKGHA Q5BL48_XENTR Q5BL48_XENTR AIFKPVMSKVMEMYQP-----------SAVVLQCG-----ADSLSGDRLGCFNLTIKGHA HDA1A_XENLA HDA1A_XENLA AIFKPVMSKVMEMFQP-----------SAVVLQCG-----ADSLSGDRLGCFNLTIKGHA HDA1B_XENLA HDA1B_XENLA AIFKPVMTKVMEMFQP-----------SAVVLQCG-----ADSLSGDRLGCFNLTIKGHA Q7ZYT5_XENLA Q7ZYT5_XENLA AIFKPVMTKVMEMFQP-----------SAVVLQCG-----ADSLSGDRLGCFNLTIKGHA Q4T0U0_TETNG Q4T0U0_TETNG HIFKPVMAKVMEMYQP-----------SAVVLQCG-----ADSLSGDRLGCFNLTIRGHA Q4SIM2_TETNG Q4SIM2_TETNG AIFKPVMAKVMEMYQP-----------SAIVLQCG-----ADSLSGDRLGCFNLTIKGTS Q5RKQ4_DANRE Q5RKQ4_DANRE AIFKPIMSKVMEMYQP-----------SAVVLQCG-----ADSLSGDRLGCFNLTIKGHA Q8JIY7_DANRE Q8JIY7_DANRE AIFKPIMSKVMEMYQP-----------SAVVLQCG-----ADSLSGDRLGCFNLTIKGHA Q6P2A8_DANRE Q6P2A8_DANRE AIFKPIMSKVMEMYQP-----------SAVVLQCG-----ADSLSGDRLGCFNLTIKGHA B5X2E0_SALSA B5X2E0_SALSA AIFKPIMTKVMEMYQP-----------SAVVLQCG-----ADSLSGDRLGCFNLTIKGHA Q4RNX4_TETNG Q4RNX4_TETNG AIFKPARARLLLSVTEVVPRADNGQGDGDVPAQCGGSPVRSDSLSGDRLGCFNLTIKGHA Q5HYD4_HUMAN Q5HYD4_HUMAN -----VMSKVMEMFQP-----------SAVVLQCG-----SDSLSGDRLGCFNLTIKGHA HDAC1_CHICK HDAC1_CHICK AIFKPVISKVMETFQP-----------SAVVLQCG-----SDSLSGDRLGCFNLTIKGHA B4DRG0_HUMAN B4DRG0_HUMAN AIFKPVMSKVMEMFQP-----------SAVVLQCG-----SDSLSGDRLGCFNLTIKGHA HDAC1_RAT HDAC1_RAT AIFKPVMSKVMEMFQP-----------SAVVLQCG-----SDSLSGDRLGCFNLTIKGHA HDAC1_BOVIN HDAC1_BOVIN AIFKPVMSKVMEMFQP-----------SAVVLQCG-----SDSLSGDRLGCFNLTIKGHA HDAC1_MOUSE HDAC1_MOUSE AIFKPVMSKVMEMFQP-----------SAVVLQCG-----SDSLSGDRLGCFNLTIKGHA Q58E49_MOUSE Q58E49_MOUSE AIFKPVMSKVMEMFQP-----------SAVVLQCG-----SDSLSGDRLGCFNLTIKGHA Q99PA2_RAT Q99PA2_RAT AIFKPVMSKVMEMFQP-----------SAVVLQCG-----SDSLSGDRLGCFNLTIKGHA Q5TEE2_HUMAN Q5TEE2_HUMAN ------------------------------------------------------------ B5BU61_HUMAN B5BU61_HUMAN AIFKPVMSKVMEMFQP-----------SAVVLQCG-----SDSLSGDRLGCFNLTIKGHA HDAC1_HUMAN HDAC1_HUMAN AIFKPVMSKVMEMFQP-----------SAVVLQCG-----SDSLSGDRLGCFNLTIKGHA HDAC1_PONAB HDAC1_PONAB AIFKPVMSKVMEMFQP-----------SAVVLQCG-----SDSLSGDRLGCFNLTIKGHA Q6IT96_HUMAN Q6IT96_HUMAN AIFKPVMSKVMEMFQP-----------SAVVLQCG-----SDSLSGDRLGCFNLTIKGHA MATCH CONSENSUS ?????????V?????P??????????????VLQ?G??????D????D????FN????G??

B1H369_XENTR B1H369_XENTR K--CLKYVLQWQLPTLILGGGGYHLPNTARCWTYLTALIVGRTLSSEIPDHEFFTEYGPD Q6GPA7_XENLA Q6GPA7_XENLA K--CLKYVLQWQLPTLILGGGGYHLPNTARCWTYLTALIVGRTLSSEIPDHEFFTEYGPD Q0VCB2_BOVIN Q0VCB2_BOVIN K--CLKYILQWELATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPD A2AWU6_MOUSE A2AWU6_MOUSE K--CLKYVLQWQLATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPD HDAC8_MOUSE HDAC8_MOUSE K--CLKYVLQWQLATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPD B1WC68_RAT B1WC68_RAT K--CLKYVLQWQLATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPD A6ND12_HUMAN A6ND12_HUMAN ---YVALYKAF------------------------------------------------- A6NGT0_HUMAN A6NGT0_HUMAN ------------------------------------------------------------ A6NMT1_HUMAN A6NMT1_HUMAN ------RALFIRTP---------------------------------------------- B4DH31_HUMAN B4DH31_HUMAN K--CLKYILQWQLATLILGGGEYKGR---------------------LPE---FVDLPPH A6ND61_HUMAN A6ND61_HUMAN ---CERYEPPAPNPGL-------------------------------------------- A6NJR3_HUMAN A6NJR3_HUMAN ------------------------------------------------------------ Q86VC8_HUMAN Q86VC8_HUMAN K--CLKYILQWQLATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPD A8MQ62_HUMAN A8MQ62_HUMAN K--CLKYILQWQLATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPD A6NGJ7_HUMAN A6NGJ7_HUMAN K--CLKYILQWQLATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTA---- B4DKN0_HUMAN B4DKN0_HUMAN K--CLKYILQWQLATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPD HDAC8_HUMAN HDAC8_HUMAN K--CLKYILQWQLATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPD Q4SY01_TETNG Q4SY01_TETNG K--CLQYVLRWRLPTLLLGGGGYNLANTARCWTYLTAAVLGKALSSEIPDHEFFTEYGPD Q7SXM0_DANRE Q7SXM0_DANRE K--CLTYILGWELPTLLLGGGGYNLANTARCWTYLTGTVLGQTLSSEIPDHEFFTEYGPD HDAC3_XENLA HDAC3_XENLA E--CVQYVKSFNIPLLVLGGGGYTVRNVARCWTYETSLLVDETISEELPYSEYFEYFAPD HDAC3_XENTR HDAC3_XENTR E--CVQYVKSFNIPLLVLGGGGYTVRNVARCWTYETSLLVDETISEELPYSEYFEYFAPD HDAC3_CHICK HDAC3_CHICK E--CVEYVKSFNIPLLVLGGGGYTVRNVARCWTYETSLLVDEAISEELPYSEYFEYFAPD Q9JM08_MOUSE Q9JM08_MOUSE E--CVEYVKSFNIPLLVLGGGGYTVRNVARCWTYETSLLVEEAISEELPYSEYFEYFAPD Q9JLX5_MOUSE Q9JLX5_MOUSE E--CVEYVKSFNIPLLVLGGGGYTVRNVARCWTYETSLLVEEAISEELPYSEYFEYFAPD HDAC3_PONAB HDAC3_PONAB E--CVEYVKSFNIPLLVLGGGGYTVRNVARCWTYETSLLVEEAISEELPYSEYFEYFAPD HDAC3_HUMAN HDAC3_HUMAN E--CVEYVKSFNIPLLVLGGGGYTVRNVARCWTYETSLLVEEAISEELPYSEYFEYFAPD HDAC3_MOUSE HDAC3_MOUSE E--CVEYVKSFNIPLLVLGGGGYTVRNVARCWTYETSLLVEEAISEELPYSEYFEYFAPD HDAC3_RAT HDAC3_RAT E--CVEYVKSFNIPLLVLGGGGYTVRNVARCWTYETSLLVEEAISEELPYSEYFEYFAPD Q3UM33_MOUSE Q3UM33_MOUSE E--CVEYVKSFNIPLLVLGGGGYTVRNVARCWTYETSLLVEEAISEELPYSEYFEYFAPD B5X1R2_SALSA B5X1R2_SALSA E--CVEFVKSFRIPLLVLGGGGYTVRNVARCWTYETSLLVDEPISDELPYSEYFEYFAPD HDAC3_DANRE HDAC3_DANRE E--CVEFVKGFKIPLLVLGGGGYTVRNVARCWTFETSLLVEESISDELPYSEYFEYFAPD HDAC3_TETNG HDAC3_TETNG E--CVEFVKSFKIPLLVLGGGGYTVRNVARCWTFETSLLLEESISDELPYSEYFEYFAPD B5X2P6_SALSA B5X2P6_SALSA K--CVEYIKSFNLPLLMLGGGGYTIRNVARCWTYETAVALDTEIPDELPYNDYFEYFGPD Q59GB9_HUMAN Q59GB9_HUMAN K--CVEVVKTFNLPLLMLGGGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPD B4DSK9_HUMAN B4DSK9_HUMAN ------------------------------------------------------------ B7Z3S4_HUMAN B7Z3S4_HUMAN ------------------------------------------------------------ Q8BQ10_MOUSE Q8BQ10_MOUSE --------KQFTFPLV---------------WCF-------------------------- Q5R6R9_PONAB Q5R6R9_PONAB ------------------------------------------------------------ Q7SYZ5_XENLA Q7SYZ5_XENLA K--CVEVVKTFNLPLLMLGGGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPD Q66J55_XENLA Q66J55_XENLA K--CVEVVKTFNLPLLMLGGGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPD Q28CG8_XENTR Q28CG8_XENTR K--CVEVVKTFNLPLLMLGGGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPD Q6GLI1_XENTR Q6GLI1_XENTR K--CVEVVKTFNLPLLMLGGGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPD HDAC2_CHICK HDAC2_CHICK K--CVEVVKTFNLPLLMLGGGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPD Q0VC01_BOVIN Q0VC01_BOVIN K--CVEVVKTFNLPLLMLGGGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPD HDAC2_MOUSE HDAC2_MOUSE K--CVEVAKTFNLPLLMLGGGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPD B1WBY8_RAT B1WBY8_RAT K--CVEVVKTFNLPLLMLGGGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPD HDAC2_HUMAN HDAC2_HUMAN K--CVEVVKTFNLPLLMLGGGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPD B3KUJ5_HUMAN B3KUJ5_HUMAN K--CVEVVKTFNLPLLMLGGGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPD B3KRS5_HUMAN B3KRS5_HUMAN K--CVEVVKTFNLPLLMLGGGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPD Q3UXH8_MOUSE Q3UXH8_MOUSE K--CVEVVKTFNLPLLMLGGGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPD Q5BL48_XENTR Q5BL48_XENTR K--CVEFIKTFNLPLLMLGGGGYTIRNVARCWTYETAVALDSEIPNELPYNDYFEYFGPD HDA1A_XENLA HDA1A_XENLA K--CVEFIKTFNLPLLMLGGGGYTIRNVARCWTYETAVALDSEIPNELPYNDYFEYFGPD HDA1B_XENLA HDA1B_XENLA K--CVEFIKTFNLPMLMLGGGGYTIRNVARCWTYETAVALDSEIPNELPYNDYFEYFGPD Q7ZYT5_XENLA Q7ZYT5_XENLA K--CVEFIKTFNLPMLMLGGGGYTIRNVARCWTYETAVALDSEIPNELPYNDYFEYFGPD Q4T0U0_TETNG Q4T0U0_TETNG K--CVEYMKSFNLPLLMLGGGGYTIRNVARCWTYETAVALDTDIPDELPYNDYFEYFGPD Q4SIM2_TETNG Q4SIM2_TETNG GWVCGTEQRC----------SGGSANGVAVCARSRQMCGVHEKFQPAPADAGRRGLHHPQ Q5RKQ4_DANRE Q5RKQ4_DANRE K--CVEYMKSFNLPLLMLGGGGYTIRNVARCWTFETAVALDSTIPNELPYSDYFEYFGPD Q8JIY7_DANRE Q8JIY7_DANRE K--CVEYMKSFNLPLLMLGGGGYTIKNVARCWTFETAVALDSTIPNELPYNDYFEYFGPD Q6P2A8_DANRE Q6P2A8_DANRE K--CVEYMKSFNLPLLMLGGGGYTIRNVARCWTFETAVALDSTIPNELPYNDYFEYFGPD B5X2E0_SALSA B5X2E0_SALSA K--CVEYMKSFNLPLLMLGGGGYTIRNVARCWTYETAVALDSSIPNELPYNDYFEYFGPD Q4RNX4_TETNG Q4RNX4_TETNG K--CVEYMKSFNLPLLMLGGGGYTIRNVARCWTYETAVALDASIPNELPYNDYFEYFGPD Q5HYD4_HUMAN Q5HYD4_HUMAN K--CVEFVKSFNLPMLMLGGGGYTIRNVARCWTYETAVALDTEIPNELPYNDYLNTWTR- HDAC1_CHICK HDAC1_CHICK K--CVEFVKSFNLPMLMLGGGGYTIRNVARCWTYETAVALDTEIPNELPYNDYFEYFGPD B4DRG0_HUMAN B4DRG0_HUMAN K--CVEFVKSFNLPMLMLGGGGYTIRNVARCWTYETAVALDTEIPNELPYNDYFEYFGPD HDAC1_RAT HDAC1_RAT K--CVEFVKSFNLPMLMLGGGGYTIRNVARCWTYETAVALDTEIPNELPYNDYFEYFGPD HDAC1_BOVIN HDAC1_BOVIN K--CVEFVKSFNLPMLMLGGGGYTIRNVARCWTYETAVALDTEIPNELPYNDYFEYFGPD HDAC1_MOUSE HDAC1_MOUSE K--CVEFVKSFNLPMLMLGGGGYTIRNVARCWTYETAVALDTEIPNELPYNDYFEYFGPD Q58E49_MOUSE Q58E49_MOUSE K--CVEFVKSFNLPMLMLGGGGYTIRNVARCWTYETAVALDTEIPNELPYNDYFEYFGPD Q99PA2_RAT Q99PA2_RAT K--CVEFVKSFNLPMLMLGGDGYTIHNVARCWTYETAVALDTEIPNELPYNDYFEYFGPD Q5TEE2_HUMAN Q5TEE2_HUMAN ------------------------------------------------------------ B5BU61_HUMAN B5BU61_HUMAN K--CVEFVKSFNLPMLMLGGGGYTIRNVARCWTYETAVALDTEIPNELPYNDYFEYFGPD HDAC1_HUMAN HDAC1_HUMAN K--CVEFVKSFNLPMLMLGGGGYTIRNVARCWTYETAVALDTEIPNELPYNDYFEYFGPD HDAC1_PONAB HDAC1_PONAB K--CVEFVKSFNLPMLMLGGGGYTIRNVARCWTYETAVALDTEIPNELPYNDYFEYFGPD Q6IT96_HUMAN Q6IT96_HUMAN K--CVEFVKSFNLPMLMLGGGGYTIRNVARCWTYETAVALDTEIPNELPYNDYFEYFGPD MATCH CONSENSUS ???C???????????L?LGGGGY???N?ARCWT??T??????????E?P????F????PD

B1H369_XENTR B1H369_XENTR YV-LEVT-PSCRPDRNDSQKVQEILQSIK-GHLKQVV----------------------- Q6GPA7_XENLA Q6GPA7_XENLA YV-LEIT-PSCRPDRNDTQKVQEILQSIK-GNLKRVV----------------------- Q0VCB2_BOVIN Q0VCB2_BOVIN YV-LEIT-PSCRPDRNEPHRVQQILNYIK-GNLKHVV----------------------- A2AWU6_MOUSE A2AWU6_MOUSE YV-LEIT-PSCRPDRNEPHRIQQILNYIK-GNLKHVV----------------------- HDAC8_MOUSE HDAC8_MOUSE YV-LEIT-PSCRPDRNEPHRIQQILNYIK-GNLKHVV----------------------- B1WC68_RAT B1WC68_RAT YV-LEIT-PSCRPDRNEPHRIQQILNYIK-GNLKHVV----------------------- A6ND12_HUMAN A6ND12_HUMAN ------------------------------------------------------------ A6NGT0_HUMAN A6NGT0_HUMAN ---L-------------------------------------------------------- A6NMT1_HUMAN A6NMT1_HUMAN ------------------------------------------------------------ B4DH31_HUMAN B4DH31_HUMAN FVHWH------------------------------------------------------- A6ND61_HUMAN A6ND61_HUMAN ------------------------------------------------------------ A6NJR3_HUMAN A6NJR3_HUMAN ------------------------------------------------------------ Q86VC8_HUMAN Q86VC8_HUMAN YV-LEIT-PSCRPDRNEPHRIQQILNYIK-GNLKHVV----------------------- A8MQ62_HUMAN A8MQ62_HUMAN YV-LEIT-PSCRPDRNEPHRIQQILNYIK-ENLK-------------------------- A6NGJ7_HUMAN A6NGJ7_HUMAN ------------------------------------------------------------ B4DKN0_HUMAN B4DKN0_HUMAN YV-LEIT-PSCRPDRNEPHRIQQILNYIK-GNLKHVV----------------------- HDAC8_HUMAN HDAC8_HUMAN YV-LEIT-PSCRPDRNEPHRIQQILNYIK-GNLKHVV----------------------- Q4SY01_TETNG Q4SY01_TETNG YS-LEIS-PSCRPDRNDLKHLDQVAHYKKGGNLKNVV----------------------- Q7SXM0_DANRE Q7SXM0_DANRE YS-LEIS-PSCRPDRNESQHLERVISTIK-GNLKNVV----------------------- HDAC3_XENLA HDAC3_XENLA FT-LHPDVSTRIENQNSRQYLDQIRQTVF-ESLKMLNHAPSVQIHDVPSDILNYERTDE- HDAC3_XENTR HDAC3_XENTR FT-LHPDVSTRIENQNSRQYLDQIRQTIF-ENLKMLNHAPSVQIHDVPSDILSYERTDE- HDAC3_CHICK HDAC3_CHICK FT-LHPDVSTRIENQNSRQYLDQIRQTIF-ENLKMLNHAPSVQIHDVPSDLLSYDRTDE- Q9JM08_MOUSE Q9JM08_MOUSE FT-LHPDVSTRIENQNSRQYLDQIRQTIF-ENLKMLNHAPSVQIHDVPADLLTYDRTDE- Q9JLX5_MOUSE Q9JLX5_MOUSE FT-LHPDVSTRIENQNSRQYLDQICQTIF-ENLKMLNHAPSVQIHDVPADLLTYDRTDE- HDAC3_PONAB HDAC3_PONAB FT-LHPDVSTRIENQNSRQYLDQIRQTIF-ENLKMLNHAPSVQIRDVPAGLLTYDRTDE- HDAC3_HUMAN HDAC3_HUMAN FT-LHPDVSTRIENQNSRQYLDQIRQTIF-ENLKMLNHAPSVQIHDVPADLLTYDRTDE- HDAC3_MOUSE HDAC3_MOUSE FT-LHPDVSTRIENQNSRQYLDQIRQTIF-ENLKMLNHAPSVQIHDVPADLLTYDRTDE- HDAC3_RAT HDAC3_RAT FT-LHPDVSTRIENQNSRQYLDQIRQTIF-ENLKMLNHAPSVQIHDVPADLLTYDRTDE- Q3UM33_MOUSE Q3UM33_MOUSE FT-LHPDVSTRIENQNSRQYLDQIRQTIF-ENLKMLNHAPSVQIHDVPADLLTYDRTDE- B5X1R2_SALSA B5X1R2_SALSA FT-LHPDVSTRIENQNSRQYLEQIRSTVF-ENLKMLNHSPSVQIHDVPSDILSYERTDE- HDAC3_DANRE HDAC3_DANRE FT-LHPDVSTRIENQNSRQYLEQIRQTVF-ENLKMLNHAPSVQIRDVPSDLLSYERPDE- HDAC3_TETNG HDAC3_TETNG FT-LHPDVSTRIENQNSRQYLEQIRQTVF-ENLKMLNHAPSVQIHDVPSDMLNYERNDE- B5X2P6_SALSA B5X2P6_SALSA FK-LHIS-PSNMTNQNTLEYMDKIKQRLF-ENLRMLPHAPGVQMQTVPEDAITDDTVDED Q59GB9_HUMAN Q59GB9_HUMAN FK-LHIS-PSNMTNQNTPEYMEKIKQRLF-ENLRMLPHAPGVQMQAIPEDAVHEDSGDED B4DSK9_HUMAN B4DSK9_HUMAN ------------------------------------------------------------ B7Z3S4_HUMAN B7Z3S4_HUMAN ------------------------------------------------------------ Q8BQ10_MOUSE Q8BQ10_MOUSE --------SSPRTSHKSFHC---------------------------------------- Q5R6R9_PONAB Q5R6R9_PONAB ------------------------------------------------------------ Q7SYZ5_XENLA Q7SYZ5_XENLA FK-LHIS-PSNMTNQNTPEYMEKIKQRLF-ENLRMLPHAPGVQMQAIPEDAVQEDSGDEE Q66J55_XENLA Q66J55_XENLA FK-LHIS-PSNMTNQNTPEYMEKIKQRLF-ENLRMLPHAPGVQMQAIPEDAVQEDSGDEE Q28CG8_XENTR Q28CG8_XENTR FK-LHIS-PSNMTNQNTPEYMEKIKQRLF-ENLRMLPHAPGVQMQAIPEDAVQEDSGDEE Q6GLI1_XENTR Q6GLI1_XENTR FK-LHIS-PSNMTNQNTPEYMEKIKQRLF-ENLRMLPHAPGVQMQAIPEDAVQEDSGDEE HDAC2_CHICK HDAC2_CHICK FK-LHIS-PSNMTNQNTPEYMEKIKQRLF-ENLRMLPHAPGVQMQAIPEDAVHEDSGDED Q0VC01_BOVIN Q0VC01_BOVIN FK-LHIS-PSNMTNQNTPEYMEKIKQRLF-ENLRMLPHAPGVQMQAIPEDAVHEDSGDED HDAC2_MOUSE HDAC2_MOUSE FK-LHIS-PSNMTNQNTPEYMEKIKQRLF-ENLRMLPHAPGVQMQAIPEDAVHEDSGDED B1WBY8_RAT B1WBY8_RAT FK-LHIS-PSNMTNQNTPEYMEKIKQRLF-ENLRMLPHAPGVQMQAIPEDAVHEDSGDED HDAC2_HUMAN HDAC2_HUMAN FK-LHIS-PSNMTNQNTPEYMEKIKQRLF-ENLRMLPHAPGVQMQAIPEDAVHEDSGDED B3KUJ5_HUMAN B3KUJ5_HUMAN FK-LHIS-PSNMTNQNTPEYMEKIKQRLF-ENLRMLPHAPGVQMQAIPEDAVHEDSGDED B3KRS5_HUMAN B3KRS5_HUMAN FK-LHIS-PSNMTNQNTPEYMEKIKQRLF-ENLRMLPHAPGVQMQAIPEDAVHEDSGDED Q3UXH8_MOUSE Q3UXH8_MOUSE FK-LHIS-PSNMTNQNTPEYMEKIKQRLF-ENLRMLPHAPGVQMQAIPEDAVHEDSGDED Q5BL48_XENTR Q5BL48_XENTR FK-LHIS-PSNMTNQNTNEYLEKIKQRLF-ENLRMLPHAPGVQMQAIPEDSVHDDSGEED HDA1A_XENLA HDA1A_XENLA FK-LHIS-PSNMTNQNTNEYLEKIKQRLF-ENLRMLPHAPGVQMQAVAEDSIHDDSGEED HDA1B_XENLA HDA1B_XENLA FK-LHIS-PSNMTNQNTNEYLEKIKQRLF-ENLRMLPHAPGVQMQAIPEDSVHDDSGEED Q7ZYT5_XENLA Q7ZYT5_XENLA FK-LHIS-PSNMTNQNTNEYLEKIKQRLF-ENLRMLPHAPGVQMQAIPEDSVHDDSGEED Q4T0U0_TETNG Q4T0U0_TETNG FKAAHSV-HRNMTNQNTQEYMDKIKQRLF-ENLRMLPHAPGVQMQAIPEDAVPDDNVDED Q4SIM2_TETNG Q4SIM2_TETNG RG-PLL----DVRDGGGLGLLHPQRAALQ-RLLRVLR----ARLQAAHQPV--------Q Q5RKQ4_DANRE Q5RKQ4_DANRE FK-LHIS-PSNMTNQNTNDYLEKIKQRLF-ENLRMLPHAPGVQMQAIPEDAVQEDSGDE- Q8JIY7_DANRE Q8JIY7_DANRE FK-LHIS-PFNMTNQNTNDYLEKIKQRLF-ENLRMLPHAPGVQMQAIPEDAVQEDSGDE- Q6P2A8_DANRE Q6P2A8_DANRE FK-LHIS-PSNMTNQ----------------------------MQAIPEDAVQEDSGDE- B5X2E0_SALSA B5X2E0_SALSA FK-LHIS-PSNMTNQNTNDYLEKIKQRLF-ENLRMLPHAPGVQMQAIPEDAVQEDSGDEE Q4RNX4_TETNG Q4RNX4_TETNG FK-LHIS-PSNMTNQNTNDYLEKIKQRLF-ENLRMLPHAPGVQMQAIPEDAVQEDSGDEE Q5HYD4_HUMAN Q5HYD4_HUMAN FK-LHIS-PSNMTNQNTNEYLEKIKQRLF-ETLRMLPHAPGVQMQAIPEDAIPEESGDED HDAC1_CHICK HDAC1_CHICK FK-LHIS-PSNMTNQNTNEYLEKIKQRLF-ENLRMLPHAPGVQMQPIPEDAVQEDSGDEE B4DRG0_HUMAN B4DRG0_HUMAN FK-LLIS-PSNMTNQNTNEYLEKIKQRLF-ENLRMLPHAPGVQMQAIPEDAIPEESGDED HDAC1_RAT HDAC1_RAT FK-LHIS-PSNMTNQNTNEYLEKIKQRLF-ENLRMLPHAPGVQMQAIPEDAIPEESGDED HDAC1_BOVIN HDAC1_BOVIN FK-LHIS-PSNMTNQNTNEYLEKIKQRLF-ENLRMLPHAPGVQMQAIPEDAIPEESGDED HDAC1_MOUSE HDAC1_MOUSE FK-LHIS-PSNMTNQNTNEYLEKIKQRLF-ENLRMLPHAPGVQMQAIPEDAIPEESGDED Q58E49_MOUSE Q58E49_MOUSE FK-LHIS-PSNMTNQNTNEYLEKIKQRLF-ENLRMLPHAPGVQMQAIPEDAIPEESGDED Q99PA2_RAT Q99PA2_RAT FK-LHIS-PSNMTNQNTNEYLEKIKQRLF-ENLRMLPHTPGVQMQAIPEDAIPEESGDED Q5TEE2_HUMAN Q5TEE2_HUMAN ------------------------------------------------------------ B5BU61_HUMAN B5BU61_HUMAN FK-LHIS-PSNMTSQNTNEYLEKIKQRLF-ENLRMLPHAPGVQMQAIPEDAIPEESGDED HDAC1_HUMAN HDAC1_HUMAN FK-LHIS-PSNMTNQNTNEYLEKIKQRLF-ENLRMLPHAPGVQMQAIPEDAIPEESGDED HDAC1_PONAB HDAC1_PONAB FK-LHIS-PSNMTNQNTNEYLEKIKQRLF-ENLRMLPHAPGVQMQAIPEDAIPEESGDED Q6IT96_HUMAN Q6IT96_HUMAN FK-LHIS-PSNMTNQNTNEYLEKIKQRLF-ENLRMLPHAPGVQMQAIPEDAIPEESGDED MATCH CONSENSUS ???L???????????N????????????????L???????????????????????????

B1H369_XENTR B1H369_XENTR ------------------------------------------------------------ Q6GPA7_XENLA Q6GPA7_XENLA ------------------------------------------------------------ Q0VCB2_BOVIN Q0VCB2_BOVIN ------------------------------------------------------------ A2AWU6_MOUSE A2AWU6_MOUSE ------------------------------------------------------------ HDAC8_MOUSE HDAC8_MOUSE ------------------------------------------------------------ B1WC68_RAT B1WC68_RAT ------------------------------------------------------------ A6ND12_HUMAN A6ND12_HUMAN ------------------------------------------------------------ A6NGT0_HUMAN A6NGT0_HUMAN ------------------------------------------------------------ A6NMT1_HUMAN A6NMT1_HUMAN ------------------------------------------------------------ B4DH31_HUMAN B4DH31_HUMAN ------------------------------------------------------------ A6ND61_HUMAN A6ND61_HUMAN ------------------------------------------------------------ A6NJR3_HUMAN A6NJR3_HUMAN ------------------------------------------------------------ Q86VC8_HUMAN Q86VC8_HUMAN ------------------------------------------------------------ A8MQ62_HUMAN A8MQ62_HUMAN ------------------------------------------------------------ A6NGJ7_HUMAN A6NGJ7_HUMAN ------------------------------------------------------------ B4DKN0_HUMAN B4DKN0_HUMAN ------------------------------------------------------------ HDAC8_HUMAN HDAC8_HUMAN ------------------------------------------------------------ Q4SY01_TETNG Q4SY01_TETNG ------------------------------------------------------------ Q7SXM0_DANRE Q7SXM0_DANRE ------------------------------------------------------------ HDAC3_XENLA HDAC3_XENLA -PDPEERGGEDNYSRPEASNEFY-----DGD-------------------HDNDKESDV- HDAC3_XENTR HDAC3_XENTR -PDPEERGSEDNYSRPEASNEFY-----DGD-------------------HDNDKESDV- HDAC3_CHICK HDAC3_CHICK -PDPEERGSEENYSRPEAANEFY-----DGD-------------------HDNDKESDV- Q9JM08_MOUSE Q9JM08_MOUSE -ADAEERGPEENYSRPEAPNEFY-----DGD-------------------HDNDKESDV- Q9JLX5_MOUSE Q9JLX5_MOUSE -ADGEERGPEENYSRPEAPNEFY-----DGD-------------------HDNDKESDV- HDAC3_PONAB HDAC3_PONAB -ADAEERGPEENYSRPEAPNEFY-----DGD-------------------HDNDKESDV- HDAC3_HUMAN HDAC3_HUMAN -ADAEERGPEENYSRPEAPNEFY-----DGD-------------------HDNDKESDV- HDAC3_MOUSE HDAC3_MOUSE -ADAEERGPEENYSRPEAPNEFY-----DGD-------------------HDNDKES--- HDAC3_RAT HDAC3_RAT -ADAEERGPEENYSRPEAPNEFY-----DGD-------------------HDNDKESDV- Q3UM33_MOUSE Q3UM33_MOUSE -ADAEERGPEENYSRPEAPNEFY-----DGD-------------------HDNDKESDV- B5X1R2_SALSA B5X1R2_SALSA -GDPDERGSEDNYSRPEAANEFY-----DGD-------------------HDNDKESDV- HDAC3_DANRE HDAC3_DANRE -ADPEERGSEENFSRPEAANEFY-----DGD-------------------HDHDKESDV- HDAC3_TETNG HDAC3_TETNG -PDPDERGAEENYTRPEAANEFY-----DGD-------------------HDNDKESDV- B5X2P6_SALSA B5X2P6_SALSA AEDPDKRMSIRASDKRIACDEEFSDSEDEGE---GGRRNEANHKKGTKRTRVEEGDK--- Q59GB9_HUMAN Q59GB9_HUMAN GEDPDKRISIRASDKRIACDEEFSDSEDEGE---GGRRNVADHKKGAKKARIEEDKKETE B4DSK9_HUMAN B4DSK9_HUMAN ------------------------------------------------------------ B7Z3S4_HUMAN B7Z3S4_HUMAN ------------------------------------------------------------ Q8BQ10_MOUSE Q8BQ10_MOUSE ------------------------------------------------------------ Q5R6R9_PONAB Q5R6R9_PONAB ------------------------------------------------------------ Q7SYZ5_XENLA Q7SYZ5_XENLA GEDPDKRISIRASDKRIACDEEFSDSEDEGE---GGRRNVADHKKKKKKKKK-------- Q66J55_XENLA Q66J55_XENLA GEDPDKRISIRASDKRIACDEEFSDSEDEGE---GGRRNVADHKKGAKKARLEEDKKETD Q28CG8_XENTR Q28CG8_XENTR GEDPDKRISIRASDKRIACDEEFSDSEDEGE---GGRRNVADHKKGAKKARLEEDKKETD Q6GLI1_XENTR Q6GLI1_XENTR GEDPDKRISIRASDKRIACDEEFSDSEDEGE---GGRRNVADHKKGAKKARLEEEKKETD HDAC2_CHICK HDAC2_CHICK GEDPDKRISIRASDKRIACDEEFSDSEDEGE---GGRRNVADHKKGAKKARIEEDKKETE Q0VC01_BOVIN Q0VC01_BOVIN GEDPDKRISIRASDKRIACDEEFSDSEDEGE---GGRRNVTDHKKGAKKARIEEDKKETE HDAC2_MOUSE HDAC2_MOUSE GEDPDKRISIRASDKRIACDEEFSDSEDEGE---GGRRNVADHKKGAKKARIEEDKKETE B1WBY8_RAT B1WBY8_RAT GEDPDKRISIRASDKRIACDEEFSDSEDEGE---GGRRNVADHKKGAKKARIEEDKKEAE HDAC2_HUMAN HDAC2_HUMAN GEDPDKRISIRASDKRIACDEEFSDSEDEGE---GGRRNVADHKKGAKKARIEEDKKETE B3KUJ5_HUMAN B3KUJ5_HUMAN GEDPDKRISIRASDKRIACDEEFSDSEDEGE---GGRRNVADHKKGAKKARIEEDKKETE B3KRS5_HUMAN B3KRS5_HUMAN GEDPDKRISIRASDKRIACDEEFSDSEDEGE---GGRRNVADHKKGAKKARIEEDKKETE Q3UXH8_MOUSE Q3UXH8_MOUSE GEDPDKRISIRASDKRIACDEEFSDSEDEGE---GGRRNVADHKKGAKKARI-------- Q5BL48_XENTR Q5BL48_XENTR EEDPDKRISIRSSDKRIACDEEFSDSEDEGE---GGRRNVASFKKVKRVKTEEEKDG--E HDA1A_XENLA HDA1A_XENLA EDDPDKRISIRSSDKRIACDEEFSDSEDEGE---GGRKNVANFKKVKRVKTEEEKEG--E HDA1B_XENLA HDA1B_XENLA EEDPDKRISIRSSDKRIACDEEFSDSEDEGE---GGRKNVANFKKVKRVKTEEEKEG--E Q7ZYT5_XENLA Q7ZYT5_XENLA EEDPDKRISIRSSDKRIACDEEFSDSEDEGE---GGRRNMASFKKLKRVKTEEEKEA--D Q4T0U0_TETNG Q4T0U0_TETNG TEDPDKRLSIRATDKRIACDEEFSDSEDEGE---GGRKNVANHKKGAKRPRVDEDKKDGE Q4SIM2_TETNG Q4SIM2_TETNG HDQPEH--------QRIPGED-------QAA---PVREPAHVASRARRADAGDPRGRAPP Q5RKQ4_DANRE Q5RKQ4_DANRE EDDPDKRISIRAHDKRIACDEEFSDSEDEGQ---GGRRNAANYKKPKRVKTEEEKDG--E Q8JIY7_DANRE Q8JIY7_DANRE EDDPDKRISIRAHDKRIACDEEFSDSEDEGQ---GGRRNAANYKKPKRVKTEEEKDG--E Q6P2A8_DANRE Q6P2A8_DANRE EDDPDKRISIRAHDKRIACDEEFSDSEDEGQ---GGRRNAANYKKPKRVKTEEEKDGEEK B5X2E0_SALSA B5X2E0_SALSA EEDPNKRISIRAHDKRIACDEEFSDSEDEAEGQGGGRRNAASFKKAKRTKTEEDKEKEGE Q4RNX4_TETNG Q4RNX4_TETNG EEDPNKRISIRAHDKRIACEEEFSDSEDEGE---GGRRNSASFKKAKRAKTEGDKEGEEK Q5HYD4_HUMAN Q5HYD4_HUMAN EDDPDKRISICSSDKRIACEEEFSDSEEEGE---GGRKNSSNFKKAKRVKTEDEKEKDPE HDAC1_CHICK HDAC1_CHICK EEDPEKRISIRNSDKRISCDEEFSDSEDEGE---GGRKNVANFKKAKRVKTEEEKEE--E B4DRG0_HUMAN B4DRG0_HUMAN EDDPDKRISICSSDKRIACEEEFSDSEEEGE---GGRKNSSNFKKAKRVKTEDEKEKDPE HDAC1_RAT HDAC1_RAT EEDPDKRISICSSDKRIACEEEFSDSDEEGE---GGRKNSSNFKKAKRVKTEDEKEKDPE HDAC1_BOVIN HDAC1_BOVIN EEDPDKRISICSSDKRIACEEEFSDSDEEGE---GGRKNSSNFKKAKRVKTEDEKEKDPE HDAC1_MOUSE HDAC1_MOUSE EEDPDKRISICSSDKRIACEEEFSDSDEEGE---GGRKNSSNFKKAKRVKTEDEKEKDPE Q58E49_MOUSE Q58E49_MOUSE EEDPDKRISICSSDKRIACEEEFSDSDEEGE---GGRKNSSNFKKAKRVKTEDEKEKDPE Q99PA2_RAT Q99PA2_RAT EEDPDKPISICSSDKCIACEEEFPDSDEEGE---GGRENSSNFKKAKRVKTEDEKEKDPE Q5TEE2_HUMAN Q5TEE2_HUMAN ------------------------------------------------------------ B5BU61_HUMAN B5BU61_HUMAN EDDPDKRISICSSDKRIACEEEFSDSEEEGE---GGRKNSSNFKKAKRVKTEDEKEKDPE HDAC1_HUMAN HDAC1_HUMAN EDDPDKRISICSSDKRIACEEEFSDSEEEGE---GGRKNSSNFKKAKRVKTEDEKEKDPE HDAC1_PONAB HDAC1_PONAB EDDPDKRISICSSDKRIACEEEFSDSEEEGE---GGRKNSSNFKKAKRVKTEDEKEKDPE Q6IT96_HUMAN Q6IT96_HUMAN EDDPDKRISICSSDKRIACEEEFSDSEEEGE---GGRKNSSNFKKAKRVKTEDEKEKDPE MATCH CONSENSUS ????????????????????????????????????????????????????????????

B1H369_XENTR B1H369_XENTR ----------------------------------------- Q6GPA7_XENLA Q6GPA7_XENLA ----------------------------------------- Q0VCB2_BOVIN Q0VCB2_BOVIN ----------------------------------------- A2AWU6_MOUSE A2AWU6_MOUSE ----------------------------------------- HDAC8_MOUSE HDAC8_MOUSE ----------------------------------------- B1WC68_RAT B1WC68_RAT ----------------------------------------- A6ND12_HUMAN A6ND12_HUMAN ----------------------------------------- A6NGT0_HUMAN A6NGT0_HUMAN ----------------------------------------- A6NMT1_HUMAN A6NMT1_HUMAN ----------------------------------------- B4DH31_HUMAN B4DH31_HUMAN ----------------------------------------- A6ND61_HUMAN A6ND61_HUMAN ----------------------------------------- A6NJR3_HUMAN A6NJR3_HUMAN ----------------------------------------- Q86VC8_HUMAN Q86VC8_HUMAN ----------------------------------------- A8MQ62_HUMAN A8MQ62_HUMAN ----------------------------------------- A6NGJ7_HUMAN A6NGJ7_HUMAN ----------------------------------------- B4DKN0_HUMAN B4DKN0_HUMAN ----------------------------------------- HDAC8_HUMAN HDAC8_HUMAN ----------------------------------------- Q4SY01_TETNG Q4SY01_TETNG ----------------------------------------- Q7SXM0_DANRE Q7SXM0_DANRE ----------------------------------------- HDAC3_XENLA HDAC3_XENLA ------EI--------------------------------- HDAC3_XENTR HDAC3_XENTR ------EI--------------------------------- HDAC3_CHICK HDAC3_CHICK ------EI--------------------------------- Q9JM08_MOUSE Q9JM08_MOUSE ------EI--------------------------------- Q9JLX5_MOUSE Q9JLX5_MOUSE ------EI--------------------------------- HDAC3_PONAB HDAC3_PONAB ------EI--------------------------------- HDAC3_HUMAN HDAC3_HUMAN ------EI--------------------------------- HDAC3_MOUSE HDAC3_MOUSE ----------------------------------------- HDAC3_RAT HDAC3_RAT ------EI--------------------------------- Q3UM33_MOUSE Q3UM33_MOUSE ------EI--------------------------------- B5X1R2_SALSA B5X1R2_SALSA ------EI--------------------------------- HDAC3_DANRE HDAC3_DANRE ------EI--------------------------------- HDAC3_TETNG HDAC3_TETNG ------EI--------------------------------- B5X2P6_SALSA B5X2P6_SALSA ------EKVEVEKSKETSTEN-------------------- Q59GB9_HUMAN Q59GB9_HUMAN DKK--TDVKEEDKSKDNSGEKTD------TKGTKSEQLSNP B4DSK9_HUMAN B4DSK9_HUMAN ----------------------------------------- B7Z3S4_HUMAN B7Z3S4_HUMAN ----------------------------------------- Q8BQ10_MOUSE Q8BQ10_MOUSE ----------------------------------------- Q5R6R9_PONAB Q5R6R9_PONAB ----------------------------------------- Q7SYZ5_XENLA Q7SYZ5_XENLA ----------------------------------------- Q66J55_XENLA Q66J55_XENLA DKKS--DVKEEDKSKDNIAEKMD------TKGVKSEQPINP Q28CG8_XENTR Q28CG8_XENTR DKKS--DVKEEDKSKDNIAEKMD------TKGVKSEQPSNP Q6GLI1_XENTR Q6GLI1_XENTR DKKS--DVKEEDKSKDNIAEKMD------TKGVKSEQPSNP HDAC2_CHICK HDAC2_CHICK DKKA--DVKEEDKSKDNSGEKTD------TKGAKSEQLSNP Q0VC01_BOVIN Q0VC01_BOVIN DKKA--DVKEEDKSKDNSGEKTD------TKGAKSEQLSNP HDAC2_MOUSE HDAC2_MOUSE DKKT--DVKEEDKSKDNSGEKTD------PKGAKSEQLSNP B1WBY8_RAT B1WBY8_RAT DKRT--DVKEEDKSKDNSGEKTD------TKGAKSEQLNNP HDAC2_HUMAN HDAC2_HUMAN DKKT--DVKEEDKSKDNSGEKTD------TKGTKSEQLSNP B3KUJ5_HUMAN B3KUJ5_HUMAN DKKT--DVKEEDKSKDNSGEKTD------TKGTKSEQLSNP B3KRS5_HUMAN B3KRS5_HUMAN DKKT--DVKEEDKSKDNSGEKTD------TKGTKSEQLSNP Q3UXH8_MOUSE Q3UXH8_MOUSE ----------------------------------------- Q5BL48_XENTR Q5BL48_XENTR EKK---DVKEEEKPKD---EKTD------SKRVKEETKSA- HDA1A_XENLA HDA1A_XENLA DKK---DVKEEEKAKD---EKTD------SKRVKEETKSV- HDA1B_XENLA HDA1B_XENLA DKK---DVKEEEKAKD---EKTD------SKRVKEETKSV- Q7ZYT5_XENLA Q7ZYT5_XENLA DKK---DVKEEEKLKD---DKTD------SKRVKEETKSA- Q4T0U0_TETNG Q4T0U0_TETNG EKK--IEIKEEENTKDISAEKTD------SKSVKTEQTTSA Q4SIM2_TETNG Q4SIM2_TETNG RQR-----GRGRGGPR---QARL------HPGPRQEDSL-- Q5RKQ4_DANRE Q5RKQ4_DANRE EKK---DVKEEEKASE---EKMD------TKGPKEELKTV- Q8JIY7_DANRE Q8JIY7_DANRE EKK---DVKEEEKASE---EKMD------TKGPKEELKTV- Q6P2A8_DANRE Q6P2A8_DANRE KGEPT-DVKEEEKASE---EKMD------TKGPKEELKTV- B5X2E0_SALSA B5X2E0_SALSA EKKAGDEKKADDKKEVKEEKVPEEEKMDTTKGPKEESKTP- Q4RNX4_TETNG Q4RNX4_TETNG EKK---EVKEEEKVPE---EE-------------------- Q5HYD4_HUMAN Q5HYD4_HUMAN EKK---EVTEEEKTKE---EKPE------AKGVKEEVKLA- HDAC1_CHICK HDAC1_CHICK EKK---DEKEEEKAKE---EKAE------PKGVKEETKST- B4DRG0_HUMAN B4DRG0_HUMAN EKK---EVTEEEKTKE---EKPE------AKGVKEEVKLA- HDAC1_RAT HDAC1_RAT EKK---EVTEEEKTKE---EKPE------AKGVKEEVKMA- HDAC1_BOVIN HDAC1_BOVIN EKK---EVTEEEKTKE---EKQE------AKGVKEEVKLA- HDAC1_MOUSE HDAC1_MOUSE EKK---EVTEEEKTKE---EKPE------AKGVKEEVKLA- Q58E49_MOUSE Q58E49_MOUSE EKK---EVTEEEKTKE---EKPE------AKGVKEEVKLA- Q99PA2_RAT Q99PA2_RAT EKK---EVTEEEKTKE---EKPE------AKGVKEEVK--- Q5TEE2_HUMAN Q5TEE2_HUMAN ----------------------------------------- B5BU61_HUMAN B5BU61_HUMAN EKK---EVTEEEKTKE---EKPE------AKGVKEEVKLA- HDAC1_HUMAN HDAC1_HUMAN EKK---EVTEEEKTKE---EKPE------AKGVKEEVKLA- HDAC1_PONAB HDAC1_PONAB EKK---EVTEEEKTKE---EKPE------AKGVKEEVKLA- Q6IT96_HUMAN Q6IT96_HUMAN EKK---EVTEEEKTKE---EKPE------AKGVKEEVKLA- MATCH CONSENSUS ?????????????????????????????????????????


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