Alignment of the gene Family HBG059373 of HOVERGEN

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Threshold: 50% 80% 100%
Size: Bigger Smaller Normal
Isoforms are ON
B5X111_SALSA B5X111_SALSA VKIAFNSALAQKALQGKEAGLVSE------------KDPEAA-VGNLSSSNQG------- Q4RP26_TETNG Q4RP26_TETNG VKIAFNSALAQKALGKDVPVAV--------------KDPELA-SAPTGNEGST------- Q52NJ7_PIG Q52NJ7_PIG VKIAFNTPAA---VQKEEVQQDVEALL---------SHTELQ-VATKEKEGFS------- Q6IBC9_HUMAN Q6IBC9_HUMAN VKIAFNTPTA---VQKEEARQDVEALLSRTVRTQILTGKELR-VATQEKEGSS------- Q53FG2_HUMAN Q53FG2_HUMAN VKIAFNTPTA---VQKEEARQDVEALLSRTVRTQILTGKELR-VATQEKEGSS------- B4E062_HUMAN B4E062_HUMAN VKIAFNTPTA---VQKEEARQDVEALLSRTVR---------------------------- ITM2A_HUMAN ITM2A_HUMAN VKIAFNTPTA---VQKEEARQDVEALLSRTVRTQILTGKELR-VATQEKEGSS------- A2ACA1_MOUSE A2ACA1_MOUSE VKIAFNTPTA---VQKEEARQDVEALVSRTVRAQILTGKELR-VVPQEKDGSS------- ITM2A_MOUSE ITM2A_MOUSE VKIAFNTPTA---VQKEEARQDVEALVSRTVRAQILTGKELR-VVPQEKDGSS------- Q4KLJ2_RAT Q4KLJ2_RAT VKIAFNTPTA---VQKEEARQDVEALVSRTVRAQILTGKELR-VVPQEKDSSS------- B5KFF8_TAEGU B5KFF8_TAEGU VKIAFNSPFALKDEPKKEAAEALA------------ADKDPE-VATHRGENSS------- Q5F3H7_CHICK Q5F3H7_CHICK VKIAFSSPFAQKGEPKKEAS---EALV---------ADKDPE-VVTQGGENSS------- Q6GL76_XENTR Q6GL76_XENTR VKIAFSSPFAGKKPSKD-----VEALV---------AETDTE-VAAQGTENST------- Q6IP70_XENLA Q6IP70_XENLA VKIAFSSPFAAKKPSKD-----VEALV---------AETDTE-VAAQGTENST------- Q7ZXQ1_XENLA Q7ZXQ1_XENLA VKIAFSSPFAGKKPSKDA-----EALV---------AETDTE-FASQGTENST------- ITM2C_RAT ITM2C_RAT VKISFQPAVAGVKAEKADK----AAASGPASASAPA--AEIL-LTPAREERPPRHRSRKG ITM2C_MOUSE ITM2C_MOUSE VKISFQPAVAGIKADKADK----AAASGPASASAPA--AEIL-LTPAREERPPRHRSRKG Q3U0F3_MOUSE Q3U0F3_MOUSE VKISFQPAVAGIKADKADK------AAASGPASASAPAAEIL-LTPAREERPPRHRSRKG B3VSC0_SHEEP B3VSC0_SHEEP VKISFQPAVAGIKGDKANKASASASASAPAPA----PAAEIL-LTPAREERPPYHRYKKG ITM2C_BOVIN ITM2C_BOVIN VKISFQPAVAGIKGDKADKASASASASAPAPT----PAAEIL-LTPAREERPPYQRYKKG B4E028_HUMAN B4E028_HUMAN VKISFQPAVAGIKGDKADK----ASASAPAPA----SATEIL-LTPAREEQPPQHRSKRG ITM2C_PIG ITM2C_PIG VKISFQPAVAGIKGDKADKASASASAPAPAPA------AEIL-LTPAREERPPHHRYKKG ITM2C_MACFA ITM2C_MACFA VKISFQPAVAGVKGDKADK----ASASAPAPA----SATEIL-LTPAREEQPPQHRSKRG B8ZZM6_HUMAN B8ZZM6_HUMAN ------------------------------------------------------------ ITM2C_HUMAN ITM2C_HUMAN VKISFQPAVAGIKGDKADK----ASASAPAPA----SATEIL-LTPAREEQPPQHRSKRG ITM2C_PONAB ITM2C_PONAB VKISFQPAVAGIKGDKADK----ASASAPAPA----SATEIL-LTPAREEQLPQHRSKRG B4DIB1_HUMAN B4DIB1_HUMAN VKISFQPAVAGIKGDKADK----ASASAPAPA----SATEIL-LTPAREEQPPQHRSKRG B3KPG4_HUMAN B3KPG4_HUMAN VKISFQPAVAGIKGDKADK----ASASAPAPA----SATEIL-LTPAR------------ Q6DGT2_DANRE Q6DGT2_DANRE VKISFQP-ITGQKAEKEGGDGDKTQIFIPHSH-----VEEEL-VLPVGRKRSS------- Q7SYK5_DANRE Q7SYK5_DANRE VKISFQQ-VTVQKPEKEN-DGDKEEIQMPYS------HKDEL-VLPVRSKKSP------- Q4RVF1_TETNG Q4RVF1_TETNG VKITFQPVSA----QKPEKDVDGDKIVIP-------QANEQL-VVPAGPKKPF------- Q4RYV9_TETNG Q4RYV9_TETNG VKITFQS-VAGQKVEKEN-DGDKSEILLPHAA-----DEEEL-VLPLRPRKSP------- B5X4A2_SALSA B5X4A2_SALSA VKITFQPISAQK--PEKELDGDKAEILMP-------YEHEEL-VLPLRPKQSH------- B5X2V3_SALSA B5X2V3_SALSA VKITFLS-VAGQKVEKEENDGEKTEILITHPM----EDDEEL-VLPLHSQRSP------- B5X357_SALSA B5X357_SALSA VKITFQS-VAGQKAEKEQNDGDKTDILITHPM----EDEEEL-VLPRRSGRSP------- Q6P3P6_XENTR Q6P3P6_XENTR VKLSFNSTLSQKDGKKEDENN--EVLIIPEA------KEPED-IVPLGQRRAW------- Q8AVF1_XENLA Q8AVF1_XENLA VKLTFNSTLGQKDGKKEDENN--EVLIIPEA------KEPED-VVPLGQRRAW------- ITM2B_PIG ITM2B_PIG VKVTFNSALAQKEAKKXEPKSGEEALIIPPDTXAVDCKDPDE-VVPVGQRRAW------- B3VSB9_SHEEP B3VSB9_SHEEP VKVTFNSALAQKEAKKDESKSGEEALIIPPDAVAVDCKDPDE-VVPVGQRRAW------- ITM2B_BOVIN ITM2B_BOVIN VKVTFNSALAQKEAKKDESKSGEEALIIPPDAVAVDCKDPDE-VVPVGQRRAW------- Q7Z528_HUMAN Q7Z528_HUMAN VKVTFNSALAQKEAKKDEPKSGEEALIIPPEAVAVDCKDPDD-VVRLGQRRAW------- Q96B24_HUMAN Q96B24_HUMAN VKVTFNSALAQKETKKDEPKSGEEALIIPPDAVAVDCKDPDD-VVPVGQRRAW------- Q9NX12_HUMAN Q9NX12_HUMAN VKVTFNSALAQKEAKKDEPKSGEEALIIPPDAVAVDCKDPDD-VVPVGQRRAW------- Q5W0A2_HUMAN Q5W0A2_HUMAN VKVTFNSALAQKEAKKDEPKSGEEALIIPPDAVAVDCKDPDD-VVPVGQRRAW------- ITM2B_HUMAN ITM2B_HUMAN VKVTFNSALAQKEAKKDEPKSGEEALIIPPDAVAVDCKDPDD-VVPVGQRRAW------- ITM2B_MACFA ITM2B_MACFA VKVTFNSALAQKEAKKDEPKSGEEALIIPPDAVAVDCKDPDD-VVPVGQRRAW------- ITM2B_PANTR ITM2B_PANTR VKVTFNSALAQKEAKKDEPKSGEEALIIPPDAVAVDCKDPDD-VVPVGQRRAW------- ITM2B_PONAB ITM2B_PONAB VKVTFNSALAQKEAKKDEPKSGEEALIIPPDAVAVDCKDPDD-VVPVGQRRAW------- Q5W0A3_HUMAN Q5W0A3_HUMAN VKVTFNSALAQKEAKKDEPKSGEEALIIPPDAVAVDCKDPDD-VVPVGQRRAW------- ITM2B_RAT ITM2B_RAT VKVTFNSALAQKEAKKDEPKSSEEALIAPPDAVAVDCKDPDD-VVPVGQRRAW------- Q9D1Q3_MOUSE Q9D1Q3_MOUSE VKVTFNSALAQKEAKKDEPKSSEEALIVPPDAVAVDCKDPGD-VVPVGQRRAW------- Q9JME4_MOUSE Q9JME4_MOUSE ------------------------------------------------------------ Q3UCT9_MOUSE Q3UCT9_MOUSE VKVTFNSALAQKEAKKDEPKSSEEALIVPPDAVAVDCKDPGD-VVPVGQRRAW------- Q3TVJ0_MOUSE Q3TVJ0_MOUSE VKVTFNSALAQKEAKKDEPKSSEEALIVPPDAVAVDCKDPGD-VVPVGQRRAW------- ITM2B_MOUSE ITM2B_MOUSE VKVTFNSALAQKEAKKDEPKSSEEALIVPPDAVAVDCKDPGD-VVPVGQRRAW------- ITM2B_CHICK ITM2B_CHICK VKVSFNSALAHKEAANKEEENS-QVLILPPD-----AKEPEDVVVPAGHKRAW------- B5FZ92_TAEGU B5FZ92_TAEGU VKVSFNSALAQKEAAKKEEENS-QVLILPPDA-----KDPED-AVPVGQRRAW------- B5FZ93_TAEGU B5FZ93_TAEGU VKVSFNSALAQKEAAKKEEENS-QVLILPPD-----AKDPED-AVPVGQRRAW------- A9JSW8_DANRE A9JSW8_DANRE VKVSFNKAFALKDPKKETLINEE-------------QDPEAV-VLVRHQPRVW------- Q7T328_DANRE Q7T328_DANRE VKVSFNKAFALKDPKKETLINEE-------------QDPEAV-VLVRHQSRVW------- Q6NV09_DANRE Q6NV09_DANRE VKLTFNSALGQKDLKKEEKDEA----LIPHD-----LDVEDV-LRVRQQSRAW------- Q803H7_DANRE Q803H7_DANRE VKLTFNSALGQKDLKKEEKDEA----LIPHD-----LDVEDV-LRVRQQSRAW------- B5X150_SALSA B5X150_SALSA VKVTFNSSFGQRDLKKACN----AEALIPEER-----DLEDG-MRVRRQSKVW------- B5X945_SALSA B5X945_SALSA VKVTFNSSFGQRDLKKACN----AEALIPEER-----DLEDG-MRVRRQSKVW------- B5XGZ5_SALSA B5XGZ5_SALSA VKVTFNSSFGQRDLKKACN----AEALIPEER-----DLEDG-MRVRRQSKVW------- B5XED6_SALSA B5XED6_SALSA VKVTFNSSFGQRDLKKACN----AEALIPEER-----DLEDG-MRVRRQSKVW------- B5X1X0_SALSA B5X1X0_SALSA VKVSFNSALGQKDMKKD------SETLIPED------KDPEVALPVRQQSKAW------- B9V3X2_EPICO B9V3X2_EPICO ------------------------------------------------------------ MATCH CONSENSUS VK??F??????????K????????????????????????????????????????????

B5X111_SALSA B5X111_SALSA -STGKCVLTLLALSFILTGAIVGAACLYRY-Y-----TPKRLYHGAMQFSE--VSSGAAV Q4RP26_TETNG Q4RP26_TETNG ---GRCLLTLLGIAFILSGLIVGGACLYRY-F-----TPKRLYHGVMQFN---TSVGRKG Q52NJ7_PIG Q52NJ7_PIG ---GRCMLTLVGLSFILAGLIVGGACIYKY-F----MPKSTIYHGEMCFFDSADPANSLQ Q6IBC9_HUMAN Q6IBC9_HUMAN ---GRCMLTLLGLSFILAGLIVGGACIYKY-F----MPKSTIYRGEMCFFDSEDPANSLR Q53FG2_HUMAN Q53FG2_HUMAN ---GRCMLTLLGLSFILAGLIVGGACIYKY-F----MPKSTIYRGEMCFFDSEDPANSLR B4E062_HUMAN B4E062_HUMAN -------------TQILTG-------------------KSTIYRGEMCFFDSEDPANSLR ITM2A_HUMAN ITM2A_HUMAN ---GRCMLTLLGLSFILAGLIVGGACIYKY-F----MPKSTIYRGEMCFFDSEDPANSLR A2ACA1_MOUSE A2ACA1_MOUSE ---GRCMLTLLGLSFILAGLIVGGACIYKY-F----MPKSTIYHGEMCFFDSEDPVNSIP ITM2A_MOUSE ITM2A_MOUSE ---GRCMLTLLGLSFILAGLIVGGACIYKY-F----MPKSTIYHGEMCFFDSEDPVNSIP Q4KLJ2_RAT Q4KLJ2_RAT ---GRCMLTLLGLSFILAGLIVGGACIYKY-F----MPKSTIYHGEMCFFDSEDAVNSIH B5KFF8_TAEGU B5KFF8_TAEGU ---GRCLLTLLGLAFILAGVVVGGACIYKY-F----MPKHKVYRGEMCYFENEGRERAV- Q5F3H7_CHICK Q5F3H7_CHICK ---GRCLLTLLGLAFILAGVVVGGACIYKY-F----MPKHKVYRGEMCYFENENRDRAV- Q6GL76_XENTR Q6GL76_XENTR ---GRCLLTLLGLAFILAGLIVGGACIYKY-F----MPRRNIYEGVMSYS-EQHDLGE-- Q6IP70_XENLA Q6IP70_XENLA ---GRCLLTLLGLAFILAGLIVGGACIYKY-F----MPRHKLYEGVMSYSEQHDLVEE-- Q7ZXQ1_XENLA Q7ZXQ1_XENLA ---GRCLLTLLGLAFILAGLIVGGACIYKY-F----MPRHKIYEGVMSYSEQQHDLAE-- ITM2C_RAT ITM2C_RAT GSVGGVCYLSMGMVVLLMGLVFASVYIYRY-FFLAQLARDNFFHCGVLYED--------- ITM2C_MOUSE ITM2C_MOUSE GSVGGVCYLSMGMVVLLMGLVFASVYIYRY-FFLAQLARDNFFHCGVLYED--------- Q3U0F3_MOUSE Q3U0F3_MOUSE GSVGGVCYLSMGMVVLLMGLVFASVYIYRY-FFLAQLARDNFFHCGVLYED--------- B3VSC0_SHEEP B3VSC0_SHEEP GSVGGVCYLSMGMVVLLMGLVFASVYIYRY-FFLAQLARDNFFHCGVLYED--------- ITM2C_BOVIN ITM2C_BOVIN GSVGGVCYLSMGMVVLLMGLVFASVYIYRY-FFLAQLARDNFFHCGVLYED--------- B4E028_HUMAN B4E028_HUMAN SSVGGVCYLSMGMVVLLMGLVFASVYIYRY-FFLAQLARDNFFRCGVLYED--------- ITM2C_PIG ITM2C_PIG SSVGGVCYLSMGMVVLLMGLVFASVYIYRY-FFLAQLARDNFFHCGVLYED--------- ITM2C_MACFA ITM2C_MACFA GSVGGVCYLSMGMVVLLMGLVFASVYIYRY-FFLAQLARDNFFRCGVLYED--------- B8ZZM6_HUMAN B8ZZM6_HUMAN ------------------------------------------------------------ ITM2C_HUMAN ITM2C_HUMAN GSVGGVCYLSMGMVVLLMGLVFASVYIYRY-FFLAQLARDNFFRCGVLYED--------- ITM2C_PONAB ITM2C_PONAB SSVGGVCYLSMGMVVLLMGLVFASVYIYRY-FFLAQLARDNFFRCGVLYED--------- B4DIB1_HUMAN B4DIB1_HUMAN SSVGGVCYLSMGMVVLLMGLVFASVYIYRY-FFLAQLARDNFFRCGVLYED--------- B3KPG4_HUMAN B3KPG4_HUMAN ------------------------------------LARDNFFRCGVLYED--------- Q6DGT2_DANRE Q6DGT2_DANRE --LSGLCCLTTALIVFTCSLIYASIYIYRY-YIIPQVPDQSQFHCRVVYED--------- Q7SYK5_DANRE Q7SYK5_DANRE --FSGLWCVVLGLVIFLSGLIMASVCLYRY-YFNPQIPEDSFFHCRMMYED--------- Q4RVF1_TETNG Q4RVF1_TETNG --PTGLCCLTFGLVVLTSVLVTASVYIYRYHYISQQIPEDSLFHCRIVYED--------- Q4RYV9_TETNG Q4RYV9_TETNG --LNGLCCLTFGLVVFMASLVLASVYVYRY-YFIPHNPGENLFHCRVLYED--------- B5X4A2_SALSA B5X4A2_SALSA --LNGLCCLTFGLVVFMSGLVLASIYVYRY-YFIQQIPEDSLFHCRVLYED--------- B5X2V3_SALSA B5X2V3_SALSA --LNGLCCLTSGLVVFMSGLVLASIYVYRY-YFIPQIPEESLFHCRVRYED--------- B5X357_SALSA B5X357_SALSA --LNGLCCLTFGLVVFMSGLVLASIYVYRY-YFIPQIPEESLFHCRVRYED--------- Q6P3P6_XENTR Q6P3P6_XENTR -----CWCMCFGLAFMLAGIVLGGAYLYKY-FA---MQR-GVYFCGIRYLEDDAALTE-- Q8AVF1_XENLA Q8AVF1_XENLA -----CWCMCFGLAFMLAGIVLGSAYLYKY-FA---MQR-GVYFCGIRYLEDDAALTE-- ITM2B_PIG ITM2B_PIG -----CWCMCFGLAFMLAGVILGGAYLYKY-FA---LQPDDVYYCGIKYIKDDVILNE-- B3VSB9_SHEEP B3VSB9_SHEEP -----CWCMCFGLAFMLAGVILGGAYLYKY-FA---FQPDDVYYCGIKYIKDDVILNE-- ITM2B_BOVIN ITM2B_BOVIN -----CWCMCFGLAFMLAGVILGGAYLYKY-FA---FQPDDVYYCGIKYIKDDVILNE-- Q7Z528_HUMAN Q7Z528_HUMAN -----CWCMCFGLAFMLAGVILGGAYLYKY-FA---LQPDDVYYCGIKYIKDDVILNE-- Q96B24_HUMAN Q96B24_HUMAN -----CWCMCFGLAFMLAGVILGGAYLYKY-FA---LQPDDVYYCGIKYIKDDVILNE-- Q9NX12_HUMAN Q9NX12_HUMAN -----CWCMCFGLAFMLAGVILGGAYLYKY-FA---LQPDDVYYCGIKYIKDDVILNE-- Q5W0A2_HUMAN Q5W0A2_HUMAN -----CWCMCFGLAFMLAGVILGGAYLYKY-FA---LQ---------------------- ITM2B_HUMAN ITM2B_HUMAN -----CWCMCFGLAFMLAGVILGGAYLYKY-FA---LQPDDVYYCGIKYIKDDVILNE-- ITM2B_MACFA ITM2B_MACFA -----CWCMCFGLAFMLAGVILGGAYLYKY-FA---LQPDDVYYCGIKYIKDDVILNE-- ITM2B_PANTR ITM2B_PANTR -----CWCMCFGLAFMLAGVILGGAYLYKY-FA---LQPDDVYYCGIKYIKDDVILNE-- ITM2B_PONAB ITM2B_PONAB -----CWCMCFGLAFMLAGVILGGAYLYKY-FA---LQPDDVYYCGIKYIKDDVILNE-- Q5W0A3_HUMAN Q5W0A3_HUMAN -----CWCMCFGLAFMLAGVILGGAYLYKY-FA---LQPDDVYYCGIKYIKDDVILNE-- ITM2B_RAT ITM2B_RAT -----CWCMCFGLAFMLAGVILGGAYLYKY-FA---LQPDDVYYCGLKYIKDDVILSE-- Q9D1Q3_MOUSE Q9D1Q3_MOUSE -----CWCMCFGLAFMLAGVILGGAYLYKY-FA---LQPDDVYYCGLKYIKDDVILNE-- Q9JME4_MOUSE Q9JME4_MOUSE --------MCFGLAFMLAGVILGGAYLYKY-FA---LQPDDVYYCGLKYIKDDVILNE-- Q3UCT9_MOUSE Q3UCT9_MOUSE -----CWCMCFGLAFMLAGVILGGAYLYKY-FA---LQPDDVYYCGLKYIKDDVILNE-- Q3TVJ0_MOUSE Q3TVJ0_MOUSE -----CWCMCFGLAFMLAGVILGGAYLYKY-FA---LQPDDVYYCGLKYIKDDVILNE-- ITM2B_MOUSE ITM2B_MOUSE -----CWCMCFGLAFMLAGVILGGAYLYKY-FA---LQPDDVYYCGLKYIKDDVILNE-- ITM2B_CHICK ITM2B_CHICK -----CWCMCFGLAFMLAGVILGGAYLYKY-FA---FQQGGVYFCGIKYIEDGLSLPE-- B5FZ92_TAEGU B5FZ92_TAEGU -----CWCMCFGLAFMLAGVFLGGAYLYKY-FA---FQQGGVYFCGIKYIEDGLSLPE-- B5FZ93_TAEGU B5FZ93_TAEGU -----CWCMCFGLAFMLAGVFLGGAYLYKY-FA---FQQGGVYFCGIKYIEDGLSLPE-- A9JSW8_DANRE A9JSW8_DANRE -----CWCFCLGLTLVLSGVVVAGAYLYRY-YV---LERDQVFICGLKYYEEDYELNE-E Q7T328_DANRE Q7T328_DANRE -----CWCFCLGLTLVLSGVVVAGAYLYRY-YV---LERDQVFICGLKYYEEDYELNE-E Q6NV09_DANRE Q6NV09_DANRE -----CWCMCLGLALILSGVVVGGAYLYRY-YF---IEEERMYFCGVNYREENYKMQDSQ Q803H7_DANRE Q803H7_DANRE -----CWCMCLGLALILSGVVVGGAYLYRY-YF---IEEERMYFCGVNYREENYKMQDSQ B5X150_SALSA B5X150_SALSA -----CWCMCLGLALMLSGVVVGGAYLYKS-YI---LQEDRVYFCGVDYRERDYMVQD-- B5X945_SALSA B5X945_SALSA -----CRYRCLGLALMLSGVVVGGAYLYKT-Y----ILERRVYWCGVDYLEQDYMVQD-- B5XGZ5_SALSA B5XGZ5_SALSA -----CWYRCLGLALMLSGVVVGGAYLYKT-Y----ILERRVYWCGVDYLEQDYMVQD-- B5XED6_SALSA B5XED6_SALSA -----CWYRCLGLALMLSGVVVGGAYLYKT-Y----ILERRVYWCGVDYLEQDYMVQD-- B5X1X0_SALSA B5X1X0_SALSA -----CWCMCLGLALMLSGVVVGGAYLYRY-YI---LEEGQVFVCGVKYREEDMMILE-E B9V3X2_EPICO B9V3X2_EPICO ---------------------VGGAYLYRY-YI---LEEGQVFVCGVNYREEDFMIQE-E MATCH CONSENSUS ???????????G????L?G????????Y?Y??????????????????Y???????????

B5X111_SALSA B5X111_SALSA ERQPYYLPR-------VEEEVEI--SDNMATIKVPPPRFAQGDPAYILHDFQKKLTAYLD Q4RP26_TETNG Q4RP26_TETNG ESQPYYLPQ-------VEEEVEI--SDNTAVISVPPPRFRPGDPAYILHDFNRKLTAYLD Q52NJ7_PIG Q52NJ7_PIG GGEPYFLP--------VMEEADIREDDNIAIIDVPVPSFSDSDPAAIIHDFEKGMTAYLD Q6IBC9_HUMAN Q6IBC9_HUMAN GGEPNFLP--------VTEEADIREDDNIAIIDVPVPSFSDSDPAAIIHDFEKGMTAYLD Q53FG2_HUMAN Q53FG2_HUMAN GGEPNFLP--------VTEEADIREDDNIAIIDVPVPSFSDSDPAAIIHDFEKGMTAYLD B4E062_HUMAN B4E062_HUMAN GGEPNFLP--------VTEEADIREDDNIAIIDVPVPSFSDSDPAAIIHDFEKGMTAYLD ITM2A_HUMAN ITM2A_HUMAN GGEPNFLP--------VTEEADIREDDNIAIIDVPVPSFSDSDPAAIIHDFEKGMTAYLD A2ACA1_MOUSE A2ACA1_MOUSE GGEPYFLP--------VTEEADIREDDNIAIIDVPVPSFSDSDPAAIIHDFEKGMTAYLD ITM2A_MOUSE ITM2A_MOUSE GGEPYFLP--------VTEEADIREDDNIAIIDVPVPSFSDSDPAAIIHDFEKGMTAYLD Q4KLJ2_RAT Q4KLJ2_RAT GGQPYFLP--------VTEEADIREDDNIAIIDVPVPSFSDSDPAAIIHDFEKGMTAYLD B5KFF8_TAEGU B5KFF8_TAEGU --EPYFLP--------IAEEADIREDDNIAIIDVPVPKFSDSDPAAIVHDFDRLLTAYLD Q5F3H7_CHICK Q5F3H7_CHICK --EPYFLP--------IAEEADIREDDNIAIIDVPVPKFSDSDPAAIVHDFDRLLTAYLD Q6GL76_XENTR Q6GL76_XENTR --EPYYLP--------VSEEADIREDDNVALITVPVPSFSESDPAAILHDFDRLLTAYLD Q6IP70_XENLA Q6IP70_XENLA ---PYYLP--------VSEEADIREDDNIALITVPVPNFAESDPAAILHDFDKLLTAYLD Q7ZXQ1_XENLA Q7ZXQ1_XENLA --EPYYLP--------VSEEADIREEDNVALITVPVPNFSDSDPAAILHDFDRLLTAYLD ITM2C_RAT ITM2C_RAT ---SLSSQIRTRLE--LEEDVKIYLEENYERINVPVPQFGGGDPADIIHDFQRGLTAYHD ITM2C_MOUSE ITM2C_MOUSE ---SLSSQIRTRLE--LEEDVKIYLEENYERINVPVPQFGGGDPADIIHDFQRGLTAYHD Q3U0F3_MOUSE Q3U0F3_MOUSE ---SLSSQIRTRLE--LEEDVKIYLEENYERINVPVPQFGGGDPADIIHDFQRGLTAYHD B3VSC0_SHEEP B3VSC0_SHEEP ---SLSSQAHTRME--LEEDVKIYLEENYERINVPVPQFGGGDPADIIHDFQRGLTAYHD ITM2C_BOVIN ITM2C_BOVIN ---SLSSQAHTRME--LEEDVKIYLEENYERINVPVPQFGGGDPADIIHDFQRGLTAYHD B4E028_HUMAN B4E028_HUMAN ---SLSSQVRTQME--LEEDVKIYLDE-HQRACAPV------------------------ ITM2C_PIG ITM2C_PIG ---SLSSQARTRME--LEEDVKIYLEENYERINVPVPQFGGGDPADIIHDFQRGLTAYHD ITM2C_MACFA ITM2C_MACFA ---SLSSQVRTQME--LEEDVKIYLDENYERINVPVPQFGGGDPADIIHDFQRGLTAYHD B8ZZM6_HUMAN B8ZZM6_HUMAN ------------ME--LEEDVKIYLDENYERINVPVPQFGGGDPADIIHDFQRGLTAYHD ITM2C_HUMAN ITM2C_HUMAN ---SLSSQVRTQME--LEEDVKIYLDENYERINVPVPQFGGGDPADIIHDFQRGLTAYHD ITM2C_PONAB ITM2C_PONAB ---SLSSQVRTQME--LEEDVKIYLDENYERINVPVPQFGGGDPADIIHDFQRGLTAYHD B4DIB1_HUMAN B4DIB1_HUMAN ---SLSSQVRTQME--LEEDVKIYLDENYE------------------------------ B3KPG4_HUMAN B3KPG4_HUMAN ---SLSSQVRTQME--LEEDVKIYLDENYERINVPVPQFGGGDPADIIHDFQRGLTAYHD Q6DGT2_DANRE Q6DGT2_DANRE ---SVAAPLRGSHE--VEENVGIYLKENYEQISVPVPDFSNTDPADIIHDFHRGLTAYHD Q7SYK5_DANRE Q7SYK5_DANRE ---PVFAPLLGRQE--LEEKVGIYLDDNYEQISVPVPDFGSGDPADIIHDFHRGLTAYYD Q4RVF1_TETNG Q4RVF1_TETNG ---SIYAPLRGRQE--LEENVGIYLDDNYEQISVPVPHFGGSDPADIIHDFQRGLTAYYD Q4RYV9_TETNG Q4RYV9_TETNG ---SSYAPLRGRQE--LEENVGIYLEDNYEKISVPVPHFGGSDPADIIHDFHRGLTAYHD B5X4A2_SALSA B5X4A2_SALSA ---SVYAPLHGRQE--LEENVGIYLDDNYEQISVPVPHFGGSDPADIIHDFQRGLTVYHD B5X2V3_SALSA B5X2V3_SALSA ---SVYAPLRGRQE--LEENVGIYLEDNYEQISVPVPHFGGSDPADIIHDFHRGLTAYHD B5X357_SALSA B5X357_SALSA ---SVYAPLRGRQE--LEENVGIYLEDNYEQISVPVPHFGGSDPADIIHDFHRGLTAYHD Q6P3P6_XENTR Q6P3P6_XENTR --PYAETP-VRYHS--FKESIQILEEEDVELINVPVPEFADNDPVDIVHDFHRKLTAYLD Q8AVF1_XENLA Q8AVF1_XENLA --PYAETP-VRYHS--FRESIQILEEEEVELINVPVPEFADSDPVDIVHDFHRKLTAYLD ITM2B_PIG ITM2B_PIG --PPANAPAARYQT--IEENIKIFEEDGVEFISVPVPEFADSDPANIVHDFNKKLTAYLD B3VSB9_SHEEP B3VSB9_SHEEP --PSADAPASRYQT--IEENIKIFEEDEVEFISVPVPEFADSDPANIVHDFNKKLTAYLD ITM2B_BOVIN ITM2B_BOVIN --PSADAPASRYQT--IEENIKIFEEDEVEFISVPVPEFADSDPANIVHDFNKKLTAYLD Q7Z528_HUMAN Q7Z528_HUMAN --PSADAPAALYQT--IEENIKIFEEEEVEFISVPVPEFADSDPANIVHDFNKKLTAYLD Q96B24_HUMAN Q96B24_HUMAN --PSADAPAALYQT--IEENIKIFEEEEVEFISVPVPEFADSDPANIVHDFNKKLTAYLD Q9NX12_HUMAN Q9NX12_HUMAN --PSADAPAALYQT--IEENIKIFEEEEVEFISVPVPEFADSDPANIVHDFNKKLTAYLD Q5W0A2_HUMAN Q5W0A2_HUMAN ------------------------------------------------------------ ITM2B_HUMAN ITM2B_HUMAN --PSADAPAALYQT--IEENIKIFEEEEVEFISVPVPEFADSDPANIVHDFNKKLTAYLD ITM2B_MACFA ITM2B_MACFA --PSADAPAALYQT--IEENIKIFEEEEVEFISVPVPEFADSDPANIVHDFNKKLTAYLD ITM2B_PANTR ITM2B_PANTR --PSADAPAALYQT--IEENIKIFEEEEVEFISVPVPEFADSDPANIVHDFNKKLTAYLD ITM2B_PONAB ITM2B_PONAB --PSADAPAALYQT--IEENIKIFEEEEVEFISVPVPEFADSDPANIVHDFNKKLTAYLD Q5W0A3_HUMAN Q5W0A3_HUMAN --PSADAPAALYQT--IEENIKIFEEEEVEFISVPVPEFADSDPANIVHDFNKKLTAYLD ITM2B_RAT ITM2B_RAT --PSADAPAARYQT--IEENIKIFEEDAVEFISVPVPEFADSDPANIVHDFNKKLTAYLD Q9D1Q3_MOUSE Q9D1Q3_MOUSE --PSADAPAARYQT--IEENIKIFEEDAVEFISVPVPEFADSDPPNIVHDFNKKLTAYLD Q9JME4_MOUSE Q9JME4_MOUSE --PSADAPAARYQT--IEENIKIFEEDAVEFISVPVPEFADSDPANIVHDFNKKLTAYLD Q3UCT9_MOUSE Q3UCT9_MOUSE --PSADAPAARYQT--IEENIKIFEEDAVEFISVPVPEFADSDPANIVHDFNKKLTAYLD Q3TVJ0_MOUSE Q3TVJ0_MOUSE --PSADAPAARYQT--IEENIKIFEEDAVEFISVPVPEFADSDPANIVHDFNKKLTAYLD ITM2B_MOUSE ITM2B_MOUSE --PSADAPAARYQT--IEENIKIFEEDAVEFISVPVPEFADSDPANIVHDFNKKLTAYLD ITM2B_CHICK ITM2B_CHICK --SGAQLKSARYHT--IEQNIQILEEEDVEFISVPVPEFADSDPADIVHDFHRRLTAYLD B5FZ92_TAEGU B5FZ92_TAEGU --PGAEAQTARYHT--IEQNIQILEEEDVEFISVPVPEFADSDPADIVHDFHRRLTAYLD B5FZ93_TAEGU B5FZ93_TAEGU --PGAEAQTARYHT--IEQNIQILEEEDVEFISVPVPEFADSDPADIVHDFHRRLTAYLD A9JSW8_DANRE A9JSW8_DANRE VDPEIGAPLRL-----IEENVSFFEDDEVELISVPVPEFKDSDP---------------- Q7T328_DANRE Q7T328_DANRE VDPEIGAPLRL-----IEENVSFFEDDEVELISVPVPEFKDSDPAGILHDFTMKLTAYLD Q6NV09_DANRE Q6NV09_DANRE EDTDMDLP-AAYKR--IEEKVRVLEDEGVELINIPVPKFSDSDPADIVHDFNRRLTAYLD Q803H7_DANRE Q803H7_DANRE EDTDMDLP-AAYKR--IEEKVRVLEDEGVELINIPVPKFSDSDPADIVHDFNRRLTAYLD B5X150_SALSA B5X150_SALSA -EDEVALPSALRH---IQESVRVLEE--VELINVPVPEFSDSDPADIVHDFKSRLTAYLD B5X945_SALSA B5X945_SALSA -EDEVALPSALRH---IQESIRVLEE--VALINVPVPEFSDSDPADIVHDFKNRLTAYLD B5XGZ5_SALSA B5XGZ5_SALSA -EDEVALPSALRH---IQESIRVLEE--VALINVPVPEFSDSDPADIVHDFKNRLTAYLD B5XED6_SALSA B5XED6_SALSA -EDEVALPSALRH---IQESIRVLEE--VALINVPVPEFSDSDPADIVHDFKNRLTAYLD B5X1X0_SALSA B5X1X0_SALSA EDVEVDLPSRFKM---IQENIRVLEDQEVALINVPVPEFDDSDPADIVHDFQRRLTAYLD B9V3X2_EPICO B9V3X2_EPICO DELEVELP-NQFQLRQLEERIRVLEREQVELINVPVPEFGDGDPADIVHDFQRRLTAYLD MATCH CONSENSUS ??????????????????E???I????????I?VPVP?F???DPA?I?HDF???LTAY?D

B5X111_SALSA B5X111_SALSA LTLRTCFVIPLNTSVVLPPQDLMDLFMQLM--SGSF--RSYLVQEDLVVTERVDDVTEMG Q4RP26_TETNG Q4RP26_TETNG LTLRTCFVIPLNTSVVLPPQDLIDLFSQLA------------------------------ Q52NJ7_PIG Q52NJ7_PIG LLLGNCYLMPLNTSIVMPPKYLLELFGKLA--RGKYLPHTYVVHEDLVAVEEIRDVSNLG Q6IBC9_HUMAN Q6IBC9_HUMAN LLLGNCYLMPLNTSIVMPPKNLVELFGKLA--SGRYLPQTYVVREDLVAVEEIRDVSNLG Q53FG2_HUMAN Q53FG2_HUMAN LLLGNCYLMPLNTSIVMPPKNLVELFGKLA--SGRYLPQTYVVREDLVAVEEIRDVSNLG B4E062_HUMAN B4E062_HUMAN LLLGNCYLMPLNTSIVMPPKNLVELFGKLA--SGRYLPQTYVVREDLVAVEEIRDVSNLG ITM2A_HUMAN ITM2A_HUMAN LLLGNCYLMPLNTSIVMPPKNLVELFGKLA--SGRYLPQTYVVREDLVAVEEIRDVSNLG A2ACA1_MOUSE A2ACA1_MOUSE LLLGNCYLMPLNTSIVMTPKNLVELFGKLA--SGKYLPHTYVVREDLVAVEEIRDVSNLG ITM2A_MOUSE ITM2A_MOUSE LLLGNCYLMPLNTSIVMTPKNLVELFGKLA--SGKYLPHTYVVREDLVAVEEIRDVSNLG Q4KLJ2_RAT Q4KLJ2_RAT LLLGNCYLMPLNTSIVMTPKNLVELFGKLA--SGKYLPHTYVVREDLVAVEEIRDVSNLG B5KFF8_TAEGU B5KFF8_TAEGU LQLGNCYVIPLNTSIVMPPRNLMDLFAQLA--TGSYLPQTYLVREEMVVTEEIDNVSDLG Q5F3H7_CHICK Q5F3H7_CHICK LQLGKCYVIPLNTSIVMPPRNLMDLFAKLA--TGSYLPQTYLVREEMVVTEEIDNVSDLG Q6GL76_XENTR Q6GL76_XENTR LQLQKCYVIDLNTSIVMPPRNLLDLFIKLA--DGSFLPQTYLVQEDLIVSEKIDDLSELG Q6IP70_XENLA Q6IP70_XENLA LQLQKCYVIDLNTSIVMLPRNLMDLFIGLA--DGSFLPQTYLVREDLVVSEKIDDLSELG Q7ZXQ1_XENLA Q7ZXQ1_XENLA LQLQKCYVIDLNTSIVMPPRNLLDLFIKLA--DGSFLPQTYLVREDLVVSEKIDDLSELG ITM2C_RAT ITM2C_RAT ISLDKCYVIELNTTIVLPPRNFWELLMNVK--RGTYLPQTYIIQEEMVVTEHVRDKEALG ITM2C_MOUSE ITM2C_MOUSE ISLDKCYVIELNTTIVLPPRNFWELLMNVK--RGTYLPQTYIIQEEMVVTEHVRDKEALG Q3U0F3_MOUSE Q3U0F3_MOUSE ISLDKCYVIELNTTIVLPPRNFWELLMNVK--RGTYLPQTYIIREEMVVTEHVRDKEALG B3VSC0_SHEEP B3VSC0_SHEEP ISLDKCYVIELNTTIVLPPRNFWELLMNVK--RGTYLPQTYIIQEEMVVTEHVSDKEALG ITM2C_BOVIN ITM2C_BOVIN ISLDKCYVIELNTTIVLPPRNFWELLMNVK--RGTYLPQTYIIQEEMVVTEHVSDKEALG B4E028_HUMAN B4E028_HUMAN ----------------------W------------------------------------- ITM2C_PIG ITM2C_PIG ISLDKCYVIELNTTIVLPPRNFWELLMNVK--RGTYLPQTYIIQEEMVVTEHVSDKEALG ITM2C_MACFA ITM2C_MACFA ISLDKCYVIELNTTIVLPPRNFWELLMNVK--RGTYLPQTYIIQEEMVDTEHVSDKEALG B8ZZM6_HUMAN B8ZZM6_HUMAN ISLDKCYVIELNTTIVLPPRNFWELLMNVK--RGTYLPQTYIIQEEMVVTEHVSDKEALG ITM2C_HUMAN ITM2C_HUMAN ISLDKCYVIELNTTIVLPPRNFWELLMNVK--RGTYLPQTYIIQEEMVVTEHVSDKEALG ITM2C_PONAB ITM2C_PONAB ISLDKCYVIELNTTIVLPPRNFWELLMNVK--RGTYLPQTYIIQEEMVVTEHVSDKEALG B4DIB1_HUMAN B4DIB1_HUMAN -------------------RNFWELLMNVK--RGTYLPQTYIIQEEMVVTEHVSDKEALG B3KPG4_HUMAN B3KPG4_HUMAN ISLDKCYVIELNTTIVLPPRNFWELLMNVK--RGTYLPQTYIIQEEMVVTEHVSDKEALG Q6DGT2_DANRE Q6DGT2_DANRE IALDKCYVTELNTTVVMPPRNLWELLINVK--KGTYLPQTYIVQEEMVVTGRVNNMHQLG Q7SYK5_DANRE Q7SYK5_DANRE IALDKCYVIELNTTIVMPPRNLWELLVNVK--RGTYLPQTYMIQEEMVVTGRVRNLRQLG Q4RVF1_TETNG Q4RVF1_TETNG IALDKCYITELNTTMVMPPRNLWELLVNVK--RGTYLPQTYIIQEEMMVTGRVRNMRQLG Q4RYV9_TETNG Q4RYV9_TETNG IALDKCYITELNTTVVMPPRNLWELLINVKVQGNPYLPQTYIIHEEMVVTGKVHNLRQLG B5X4A2_SALSA B5X4A2_SALSA IALDKCYVIELNTTLVMPPRNLWELLVNVK--KGTYLPQTYIIQEEMVVTGRVRNMRPLG B5X2V3_SALSA B5X2V3_SALSA IALDKCYVIELNTTIVMPPRNLWELLVNVK--KGTYLPQTYIIQEEMVVTGKVHNMRQLG B5X357_SALSA B5X357_SALSA IALDKCYVIELNTTIVMPPRNLWELLVNVK--KGTYLPQTYIIQEEMFVTGKVHNMRQLG Q6P3P6_XENTR Q6P3P6_XENTR LNLNKCYVIPLNTSIVMPPKNFLELLLNIK--AGTYLPQSYLVHEQMIVTDRIENVDQLG Q8AVF1_XENLA Q8AVF1_XENLA LNLNKCYVIPLNTSIVMPPKNFLELLLNIK--AGTYLPQSYLVHEQMIVTDRIENVDQLG ITM2B_PIG ITM2B_PIG LNLDKCYVIPLNTSIVMPPRNLLELLINIK--AGTYLPQSYLIHEHMVITDRIENIDHLG B3VSB9_SHEEP B3VSB9_SHEEP LNLDKCYVIPLNTSIVMPPKNLLELLINIK--AGTYLPQSYLIHEHMVITDRIENIDHLG ITM2B_BOVIN ITM2B_BOVIN LNLDKCYVIPLNTSIVMPPKNLLELLINIK--AGTYLPQSYLIHEHMVITDRIENIDHLG Q7Z528_HUMAN Q7Z528_HUMAN LNLDKCYVIPLNTSIVMPPRNLLELLINIK--AGTYLPQSYLIHEHMVITDRIENIDHLG Q96B24_HUMAN Q96B24_HUMAN LNLDKCYVIPLNTSIVMPPRNLLELLINIK--AGTYLPQSYLIHEHMVITDRIENIDHLG Q9NX12_HUMAN Q9NX12_HUMAN LNLDKCYVIPLNTSIVMPPRNLLELLINIK--AGTYLPQSYLIHEHMVITDRIENIDHLG Q5W0A2_HUMAN Q5W0A2_HUMAN --------------------------------AGTYLPQSYLIHEHMVITDRIENIDHLG ITM2B_HUMAN ITM2B_HUMAN LNLDKCYVIPLNTSIVMPPRNLLELLINIK--AGTYLPQSYLIHEHMVITDRIENIDHLG ITM2B_MACFA ITM2B_MACFA LNLDKCYVIPLNTSIVMPPRNLLELLINIK--AGTYLPQSYLIHEHMVITDRIENIDHLG ITM2B_PANTR ITM2B_PANTR LNLDKCYVIPLNTSIVMPPRNLLELLINIK--AGTYLPQSYLIHEHMVITDRIENIDHLG ITM2B_PONAB ITM2B_PONAB LNLDKCYVIPLNTSIVMPPRNLLELLINIK--AGTYLPQSYLIHEHMVITDRIENIDHLG Q5W0A3_HUMAN Q5W0A3_HUMAN LNLDKCYVIPLNTSIVMPPRNLLELLINIK--AGTYLPQSYLIHEHMVITDRIENIDHLG ITM2B_RAT ITM2B_RAT LNLDKCYVIPLNTSIVMPPRNLLELLINIK--AGTYLPQSYLIHEHMVITDRIENVDHLG Q9D1Q3_MOUSE Q9D1Q3_MOUSE LNLDKCYVFPLNTSIVMPPKNLLELLINIK--AGTYLPQSYLIHEHMVITDRIENVDNLG Q9JME4_MOUSE Q9JME4_MOUSE LNLDKCYVIPLNTSIVMPPKNLLELLINIK--AGTYLPQSYLIHEHMVITDRIENVDNLG Q3UCT9_MOUSE Q3UCT9_MOUSE LNLDKCYVIPLNTSIVMPPKNLLELLINIK--AGTYLPQSYLIHEHMVITDRIENVDNLG Q3TVJ0_MOUSE Q3TVJ0_MOUSE LNLDKCYVIPLNTSIVMPPKNLLELLINIK--AGTYLPQSYLIHEHMVITDRIENVDNLG ITM2B_MOUSE ITM2B_MOUSE LNLDKCYVIPLNTSIVMPPKNLLELLINIK--AGTYLPQSYLIHEHMVITDRIENVDNLG ITM2B_CHICK ITM2B_CHICK LSLDKCYVIPLNTSVVMPPKNFLELLINIK--AGTYLPQSYLIHEQMIVTDRIENVDQLG B5FZ92_TAEGU B5FZ92_TAEGU LSLDKCYVIPLNTSVVMPPKKF----------PGA--AHQY------------------- B5FZ93_TAEGU B5FZ93_TAEGU LSLDKCYVIPLNTSVVMPPKK--------------------------------------- A9JSW8_DANRE A9JSW8_DANRE -------------------RDFQEFLVNIK--EGMYLPQTYLIHEEMMVTEKLDDTSDLG Q7T328_DANRE Q7T328_DANRE LNLDKCYIITLNTSVVMPPRDFQEFLVNIK--EGMYLPQTYLIHEEMMVTEKLDDTSDLG Q6NV09_DANRE Q6NV09_DANRE LRLNKCYVIPLNTSVVMPPKDFLELLVNIK--AGTYLPQSYLVRDQMMVTGKVEHVDQLG Q803H7_DANRE Q803H7_DANRE LRLNKCYVIPLNTSVVMPPKDFLELLVNIK--AGTYLPQSYLVREQMMVTGKVEHVDQLG B5X150_SALSA B5X150_SALSA LSLNKCYVIPLNTSIVMPPKDLLELLINIK--AGTYLPQSYLVHEQMMVTERLENVDQLG B5X945_SALSA B5X945_SALSA LSLNKCYVIPLNTSIVMPPKDLLELLINIK--AGTYLPQSYLVHEQMMVTERLENVDQLG B5XGZ5_SALSA B5XGZ5_SALSA LSLNKCYVIPLNTSIVMPPKDLPELLINIK--AGTYLPQSYLVHEQMMVTERLENVDQLG B5XED6_SALSA B5XED6_SALSA LSLNKCYVIPLNTSIVMPPKDLLELLINIK--AGTYLPQSYLVHEQMMVTERLENVDQLG B5X1X0_SALSA B5X1X0_SALSA LFLNKCYVIPLNTSIVMPPKDFLELLVNIK--AGTYLPQSYLVHEEMMVTERLEDVEQLG B9V3X2_EPICO B9V3X2_EPICO LSLNKCYVIPLNTSIVMPPRDFLELLVNVK--AGTYLPQSYLLHEEMIVTERLQHVDQLG MATCH CONSENSUS ??L??CY???LNT??V?PP????EL????????G?YLPQ?Y???E?????????????LG

B5X111_SALSA B5X111_SALSA FYIRRLCEGKDTYRM-QRRSDLTGGGIHKRSVEECFTIRHFENTFVTETKICKA--- Q4RP26_TETNG Q4RP26_TETNG ----------------------V---------------------------------- Q52NJ7_PIG Q52NJ7_PIG IFIYQLCNNRKSFRL-RRRDLLL--GFNKRAIDKCWKIRHFPNEFIVETKICQE--- Q6IBC9_HUMAN Q6IBC9_HUMAN IFIYQLCNNRKSFRL-RRRDLLL--GFNKRAIDKCWKIRHFPNEFIVETKICQD--- Q53FG2_HUMAN Q53FG2_HUMAN IFIYQLCNNRKSFRL-RRRDLLL--GFNKRAIDKCWKIRHFLNEFIVETKICQE--- B4E062_HUMAN B4E062_HUMAN IFIYQLCNNRKSFRL-RRRDLLL--GFNKRAIDKCWKIRHFPNEFIVETKICQE--- ITM2A_HUMAN ITM2A_HUMAN IFIYQLCNNRKSFRL-RRRDLLL--GFNKRAIDKCWKIRHFPNEFIVETKICQE--- A2ACA1_MOUSE A2ACA1_MOUSE IFIYQLCNNRKSFRL-RRRDLLL--GFNKRAIDKCWKIRHFPNEFIVETKICQE--- ITM2A_MOUSE ITM2A_MOUSE IFIYQLCNNRKSFRL-RRRDLLL--GFNKRAIDKCWKIRHFPNEFIVETKICQE--- Q4KLJ2_RAT Q4KLJ2_RAT IFIYQLCNNRKSFRL-RRRDLLL--GFNKRAIDKCWKIRHFPNEFIVETKICQE--- B5KFF8_TAEGU B5KFF8_TAEGU IFIYQLCVGKETFRL-QRRDQIL--GVQKRAAENCHSIRHFENSFVVETKICQQ--- Q5F3H7_CHICK Q5F3H7_CHICK IFIYQLCVGKETFKL-QRRDQIM--GLQKRSVENCHSIRHFENSFVVETKICQQ--- Q6GL76_XENTR Q6GL76_XENTR IFIYQHCVGRETYRL-VRRDQII--GLQKRSVQDCFTINHFENNFVTSTKICKN--- Q6IP70_XENLA Q6IP70_XENLA IFIYQHCFGRETYRL-VRREQII--GLQKRSVENCITINHFENDFVTSTRICT---- Q7ZXQ1_XENLA Q7ZXQ1_XENLA IFIYQHCFRRETYRL-VRREQII--GLQKRSVEDCITIHHFENDFVTSTRICN---- ITM2C_RAT ITM2C_RAT SFIYHLCNGKDTYRL-RRRATRR--RINKRGAKNCNAIRHFENTFVVETLICGVV-- ITM2C_MOUSE ITM2C_MOUSE SFIYHLCNGKDTYRL-RRRSTRR--RINKRGGKNCNAIRHFENTFVVETLICGVV-- Q3U0F3_MOUSE Q3U0F3_MOUSE SFIYHLCNGKDTYRL-RRRSTRR--RINKRGGKNCNAIRHFENTFVVETLICGVV-- B3VSC0_SHEEP B3VSC0_SHEEP SFIYHLCSGKDTYRL-RRRATRR--RINKREAKNCNAIRHFENTFVVETVICGVV-- ITM2C_BOVIN ITM2C_BOVIN SFIYHLCSGKDTYRL-RRRATRR--RINKREAKNCNAIRHFENTFVVETLICGVV-- B4E028_HUMAN B4E028_HUMAN ----------------------R--R------------------------------- ITM2C_PIG ITM2C_PIG SFIYHLCNGKDTYRL-RRRATRR--RINKRGAKNCNAIRHFENTFVVETLICGVV-- ITM2C_MACFA ITM2C_MACFA SFIYHLCNGKDTYRL-RRRATRR--RINKRGAKNCNAIRHFENTFVVETLICGVV-- B8ZZM6_HUMAN B8ZZM6_HUMAN SFIYHLCNGKDTYRL-RRRATRR--RINKRGAKNCNAIRHFENTFVVETLICGVV-- ITM2C_HUMAN ITM2C_HUMAN SFIYHLCNGKDTYRL-RRRATRR--RINKRGAKNCNAIRHFENTFVVETLICGVV-- ITM2C_PONAB ITM2C_PONAB SFIYHLCNGKDTYRL-RRRATRR--RINKRGAKNCNAIRHFENTFVVETLICGVV-- B4DIB1_HUMAN B4DIB1_HUMAN SFIYHLCNGKDTYRL-RRRATRR--RINKRGAKNCNAIRHFENTFVVETLICGVV-- B3KPG4_HUMAN B3KPG4_HUMAN SFIYHLCNGKDTYRL-RRRATRR--RINKRGAKNCNAIRHFENTFVVETLICGVV-- Q6DGT2_DANRE Q6DGT2_DANRE RFIYRLCNGKDTYRL-RRRTSRR--RISKRDAQNCHRIRHFENTFVVETVICETP-- Q7SYK5_DANRE Q7SYK5_DANRE PFIHRLCYAKETYRL-RRRSGQR--RIDKRETKNCHTIRHFENTFAVETKICERLLL Q4RVF1_TETNG Q4RVF1_TETNG PFIHRLCYGKETYRL-RRRSQRR--RIDRRETKKCHSIRHFENTFVVETVIC----- Q4RYV9_TETNG Q4RYV9_TETNG PFIYHLCHGKDTYRL-SRRVSHR--RISKRETKDCHHIRHFENTFVVETMICD---- B5X4A2_SALSA B5X4A2_SALSA PFIHRLCYGKDTYRLKRRRDARR--RIDKREARNCHSIRHFENTFVVETVICDRV-- B5X2V3_SALSA B5X2V3_SALSA PFIYRLCNGKDTYRL-KRH-ARR--RINKREAANCHRIRHFENTFVVETVICDGA-- B5X357_SALSA B5X357_SALSA PFIFRLCNGKDTYRL-TRR-ARR--RINKREVANCHRIRHFENTFVVETVICDGV-- Q6P3P6_XENTR Q6P3P6_XENTR FFIYRLCRDKETYKL-QRKETIR--GFQKREAENCHTIRHFANRFAVETQICEH--- Q8AVF1_XENLA Q8AVF1_XENLA FFIYRLCRDKDTYKL-QRKETIR--GFHKREAENCHTIRHFANKFPVETQICEH--- ITM2B_PIG ITM2B_PIG FYIYRLCHDKETYKL-QRKETVK--GIQKREASNCATIRHFENKFAVETLICS---- B3VSB9_SHEEP B3VSB9_SHEEP FYIYRLCHDKETYKL-QRRDTIK--GIQKRAASTCVTIRHFENKFAVETLICS---- ITM2B_BOVIN ITM2B_BOVIN FYIYRLCHDKETYKL-QRRETIK--GIQKRSADVCVTIRHFENRFAVETLICP---- Q7Z528_HUMAN Q7Z528_HUMAN FFIYRLCHDKETYKL-QRRETIK--GIQKREASNCFAIRHFENKFAVETLICS---- Q96B24_HUMAN Q96B24_HUMAN FFIYRLCHDKETYKL-QRRETIK--GIQKREASNCFAIRHFENKFAVETLICS---- Q9NX12_HUMAN Q9NX12_HUMAN FFIYRLCHDKETHKL-QRRETIK--GIQKREASNCFAIRHFENKFAVETLICS---- Q5W0A2_HUMAN Q5W0A2_HUMAN FFIYRLCHDKETYKL-QRRETIK--GIQKREASNCFAIRHFENKFAVETLICS---- ITM2B_HUMAN ITM2B_HUMAN FFIYRLCHDKETYKL-QRRETIK--GIQKREASNCFAIRHFENKFAVETLICS---- ITM2B_MACFA ITM2B_MACFA FFIYRLCHDKETYKL-QRRETIK--GIQKREASNCFAIRHFENKFAVETLICS---- ITM2B_PANTR ITM2B_PANTR FFIYRLCHDKETYKL-QRRETIK--GIQKREASNCFAIRHFENKFAVETLICS---- ITM2B_PONAB ITM2B_PONAB FFIYRLCHDKETYKL-QRRETIK--GIQKREASNCFAIRHFENKFAVETLICS---- Q5W0A3_HUMAN Q5W0A3_HUMAN FFIYRLCHDKETYKL-QRRETIK--GIQKREASNCFAIRHFENKFAVETLICS---- ITM2B_RAT ITM2B_RAT FFIYRLCHDKETYKL-QRRETIR--GIQKREASNCFTIRHFENKFAVETLICS---- Q9D1Q3_MOUSE Q9D1Q3_MOUSE FFIYRLCHDKETYKL-QRRETIR--GIQKREASNCFTIRHFENKFAVETLICS---- Q9JME4_MOUSE Q9JME4_MOUSE FFIYRLCHDKETYKL-QRRETIR--GIQKREASNCFTIRHFENKFAVETLICS---- Q3UCT9_MOUSE Q3UCT9_MOUSE FFIYRLCHDKETYKL-QRRETIR--GIQKRETSNCFTIRHFENKFAVETLICS---- Q3TVJ0_MOUSE Q3TVJ0_MOUSE FFIYRLCHDKETYKL-QRRETIR--GIQKREASNCFTIRHFENKFDVETLICS---- ITM2B_MOUSE ITM2B_MOUSE FFIYRLCHDKETYKL-QRRETIR--GIQKREASNCFTIRHFENKFAVETLICS---- ITM2B_CHICK ITM2B_CHICK FFIYRLCRGKETYKL-QRKEAMK--GIQKREAVNCRKIRHFENRFAMETLICEQ--- B5FZ92_TAEGU B5FZ92_TAEGU --------------------------------------------------------- B5FZ93_TAEGU B5FZ93_TAEGU ----------------KKK-------------------------------------- A9JSW8_DANRE A9JSW8_DANRE YYINNLCKDKDTYRL-QRRDTIL--GMQKREALNCHKIRHFENKFVVETLICEP--- Q7T328_DANRE Q7T328_DANRE YYINNLCKDKDTYRL-QRRDTIL--GMQKREALNCHKIRHFENKFVVETLICEP--- Q6NV09_DANRE Q6NV09_DANRE YFIYGLCRGRDTYKL-ERRETVL--GIQKREALNCHKILHFENKFVVETLICEQ--- Q803H7_DANRE Q803H7_DANRE YFIYGLCRGRDTYKL-ERRETVL--GIQKREALNCHKILHFENKFVVETLICEQ--- B5X150_SALSA B5X150_SALSA YFIYSLCKGRDTYKL-ERRDTIL--GREKREALNCRTIRHFENKFVVETVICEP--- B5X945_SALSA B5X945_SALSA YFIYSLCKGRDTYKL-ERRETIL--GREKREALNCRTIRHFENKFVVETLICGP--- B5XGZ5_SALSA B5XGZ5_SALSA YFIYSLCKGRDTYKL-ERRETIL--GREKREALNCRTIRHFENKFVVETLIYEP--- B5XED6_SALSA B5XED6_SALSA YFIYSLCKGRDTYKL-ERRETIL--GREKREALNCRTIRHFENKFVVETLICEP--- B5X1X0_SALSA B5X1X0_SALSA YFINNLCQGKDTYKL-ERRDRIL--GMQKREALNCHKIRHFENKFVVETLICEP--- B9V3X2_EPICO B9V3X2_EPICO YFIYNLCRGKDTYKL-QRRDRIL--GMQKREALNCHKIRHFESNVVVETLICEP--- MATCH CONSENSUS ?FIY?LC????T??L??RR?????????KR????C??IRHF?N?F?VET?IC?????


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