Alignment of the gene Family HBG062385 of HOVERGEN

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Isoforms are ON
MF2L2_HUMAN MF2L2_HUMAN ------------------------------------------------------------ A2AEU1_MOUSE A2AEU1_MOUSE AEAGPPPARFPPARLPPAGSSRAGLPPTGSPPASTPALASQWLAVKRLPRAAAKAPNLQL Q8BLE2_MOUSE Q8BLE2_MOUSE ------------------------------------------------------------ Q99N72_MOUSE Q99N72_MOUSE ------------------------------------------------------------ Q7TNJ5_MOUSE Q7TNJ5_MOUSE ------------------------------------------------------------ Q8C067_MOUSE Q8C067_MOUSE ------------------------------------------------------------ A2AET8_MOUSE A2AET8_MOUSE ------------------------------------------------------------ B7Z3Y5_HUMAN B7Z3Y5_HUMAN ------------------------------------------------------------ Q5JYJ2_HUMAN Q5JYJ2_HUMAN ------------------------------MAEANPR----------------------- B7Z3Z2_HUMAN B7Z3Z2_HUMAN -------------------------------------MPQAAASAPWTSVSCGRIPGLPQ B2R9S6_HUMAN B2R9S6_HUMAN ------------------------------------------------------------ B7Z869_HUMAN B7Z869_HUMAN ------------------------------------------------------------ B7ZAV1_HUMAN B7ZAV1_HUMAN ------------------------------------------------------------ Q5JYJ7_HUMAN Q5JYJ7_HUMAN ------------------------------MPQAAAS-------APWTSVSCGRIPGLPQ Q5JYJ5_HUMAN Q5JYJ5_HUMAN ------------------------------------------------------------ Q5JYJ6_HUMAN Q5JYJ6_HUMAN ------------------------------------------------------------ Q5JYJ3_HUMAN Q5JYJ3_HUMAN ------------------------------------------------------------ MCF2_HUMAN MCF2_HUMAN ------------------------------------------------------------ Q4S0P7_TETNG Q4S0P7_TETNG ------------------------------------------------------------ B8A4Q6_DANRE B8A4Q6_DANRE ------------------------------------------------------------ MCF2L_RAT MCF2L_RAT ------------------------------------------------------------ Q3UHQ9_MOUSE Q3UHQ9_MOUSE ------------------------------------------------------------ Q6PDM6_MOUSE Q6PDM6_MOUSE ------------------------------------------------------------ Q8C7Z1_MOUSE Q8C7Z1_MOUSE ------------------------------------------------------------ Q80U26_MOUSE Q80U26_MOUSE ------------------------------------------------------------ MCF2L_MOUSE MCF2L_MOUSE ---------------------------------------MSDCWCFIFCKEHVRSNPLSP Q003U3_MOUSE Q003U3_MOUSE ------------------------------------------------------------ B5SNI0_OTOGA B5SNI0_OTOGA -----------------------MRFWLRH----------------------DEMALEEM B3KT13_HUMAN B3KT13_HUMAN ------------------------------------------------------------ A9X169_PAPAN A9X169_PAPAN ------------------------------------------------------------ B1MTD7_CALMO B1MTD7_CALMO ------------------------------------------------------------ Q5REI0_PONAB Q5REI0_PONAB ------------------------------------------------------------ B4DHD6_HUMAN B4DHD6_HUMAN ------------------------------------------------------------ B4DIL6_HUMAN B4DIL6_HUMAN ------------------------------------------------------------ B7Z9K4_HUMAN B7Z9K4_HUMAN ------------------------------------------------------------ MCF2L_HUMAN MCF2L_HUMAN ---------------------------------------MFDCWRFILCKRPGSNSYSSP A8MU87_HUMAN A8MU87_HUMAN ------------------------------------------------------------ B7ZBJ8_HUMAN B7ZBJ8_HUMAN ------------------------------------------------------------ B8A4Q9_DANRE B8A4Q9_DANRE ------------------------------------------------------------ Q4RY59_TETNG Q4RY59_TETNG ------------------------------------------------------------ Q4SVF8_TETNG Q4SVF8_TETNG ------------------------------------------------------------ Q4RP67_TETNG Q4RP67_TETNG ------------------------------------------------------------ Q7ZZ90_DANRE Q7ZZ90_DANRE ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

MF2L2_HUMAN MF2L2_HUMAN ----------MLSCLKEEMPPQELTRRLATVITHVDEIMQQEVRPLMAVEIIEQ------ A2AEU1_MOUSE A2AEU1_MOUSE NQDHCSFVPFTQAVPVQVDMAMALHRVRIAEKYGKNYLCLLQAVFLAETGLLLQLKDINH Q8BLE2_MOUSE Q8BLE2_MOUSE -------------------MAMALHRVRIAEKYGKNYLCLLQAVFLAETGLLLQLKDINH Q99N72_MOUSE Q99N72_MOUSE ------------------------------------------------------------ Q7TNJ5_MOUSE Q7TNJ5_MOUSE ------------------------------------------------------------ Q8C067_MOUSE Q8C067_MOUSE ------------------------------------------------------------ A2AET8_MOUSE A2AET8_MOUSE ------------------------------------------------------------ B7Z3Y5_HUMAN B7Z3Y5_HUMAN ------------------------------------------------------------ Q5JYJ2_HUMAN Q5JYJ2_HUMAN ------------------------------------------------------------ B7Z3Z2_HUMAN B7Z3Z2_HUMAN NPNGCTFMPIAQAIPLQVDMAMALQRVRIAEKYGKNYLCLLQAVFVAETDLLLRIKDISH B2R9S6_HUMAN B2R9S6_HUMAN ------------------------------------------------------------ B7Z869_HUMAN B7Z869_HUMAN ------------------------------------------------------------ B7ZAV1_HUMAN B7ZAV1_HUMAN ------------------------------------------------------------ Q5JYJ7_HUMAN Q5JYJ7_HUMAN NPDGCTFMPIAQAIPLQVDMAMALQRVRIAEKYGKNYLCLLQAVFVAETDLLLRIKDISH Q5JYJ5_HUMAN Q5JYJ5_HUMAN ------------------------------------------------------------ Q5JYJ6_HUMAN Q5JYJ6_HUMAN ------------------------------------------------------------ Q5JYJ3_HUMAN Q5JYJ3_HUMAN ------------------------------------------------------------ MCF2_HUMAN MCF2_HUMAN ------------------------------------------------------------ Q4S0P7_TETNG Q4S0P7_TETNG -----------------------------------DEIMQLDSAPLCAADIAPE------ B8A4Q6_DANRE B8A4Q6_DANRE ------------------------------------------------------------ MCF2L_RAT MCF2L_RAT ------------------------------------------------------------ Q3UHQ9_MOUSE Q3UHQ9_MOUSE ------------------------------------------------------------ Q6PDM6_MOUSE Q6PDM6_MOUSE ------------------MALEEMVQRLNAVSKNTDEIMHQDIVPLCAADIQEQ------ Q8C7Z1_MOUSE Q8C7Z1_MOUSE ---------MRFWLRNEEMALEEMVQRLNAVSKNTDEIMHQDIVPLCAADIQEQ------ Q80U26_MOUSE Q80U26_MOUSE ------------------------------------------------------------ MCF2L_MOUSE MCF2L_MOUSE QHDGASREEADHQVDVSDGIRLVPDKAEATAATASDEIMHQDIVPLCAADIQEQ------ Q003U3_MOUSE Q003U3_MOUSE -------------------------------MRPTDEIMHQDIVPLCAADIQEQ------ B5SNI0_OTOGA B5SNI0_OTOGA VQRLS------------------------AVSTRTDEIMHQDIVPLCAADIQDQ------ B3KT13_HUMAN B3KT13_HUMAN --------------------MWLSQRVLPPLPFPADAWEPSEVLGIFSQHRSHA------ A9X169_PAPAN A9X169_PAPAN -----------MTVSRLSLLCRDLWALWLLLKAGADEIMHQDIVPLCAADIQDQ------ B1MTD7_CALMO B1MTD7_CALMO ------------------------------------------------------------ Q5REI0_PONAB Q5REI0_PONAB ------------------------------------------------------------ B4DHD6_HUMAN B4DHD6_HUMAN -----------MTVRRLSLLCRDLWALWLLLKAGADEIMHQDIVPLCAADIQDQ------ B4DIL6_HUMAN B4DIL6_HUMAN ---------MRFWLRTEEMALEEMVQRLNAVSKHTDEIMHQDIVPLCAADIQDQ------ B7Z9K4_HUMAN B7Z9K4_HUMAN ---------MRFWLRTEEMALEEMVQRLNAVSKHTDEIMHQDIVPLCAADIQDQ------ MCF2L_HUMAN MCF2L_HUMAN QRPNEAKKEETDHQIDVSDVIRLVQDTPEATAMATDEIMHQDIVPLCAADIQDQ------ A8MU87_HUMAN A8MU87_HUMAN ------------------------------------------------------------ B7ZBJ8_HUMAN B7ZBJ8_HUMAN ------------------------------------------------------------ B8A4Q9_DANRE B8A4Q9_DANRE -----------MELNRVSLLCQDITKLWLQLKVLTDEIMQQESSPLCAADISPD------ Q4RY59_TETNG Q4RY59_TETNG -----------MALNRVSQLCHDITRLWLHLKMLTDDIVQQDSGPLCAAQIGSE------ Q4SVF8_TETNG Q4SVF8_TETNG ------------------------------------------------------------ Q4RP67_TETNG Q4RP67_TETNG ----------------------VPVSMKEVGGHIEKQVAYLSGEALVKYFSVNHPFASFF Q7ZZ90_DANRE Q7ZZ90_DANRE ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

MF2L2_HUMAN MF2L2_HUMAN LHRQFAI-LSGGRGEDGAPIITFPEFSGFKHIPDEDFLNVMTYLTSIPSVEAASIGFIVV A2AEU1_MOUSE A2AEU1_MOUSE FLMQDIAFLSGGRGKDNAWIITFPENCNFRCIPEEVIAKVLNYLTSIARQSGSDSRFTII Q8BLE2_MOUSE Q8BLE2_MOUSE FLMQDIAFLSGGRGKDNAWIITFPENCNFRCIPEEVIAKVLNYLTSIARQSGSDSRFTII Q99N72_MOUSE Q99N72_MOUSE ------------------------------------------------------------ Q7TNJ5_MOUSE Q7TNJ5_MOUSE ------------------------------------------------------------ Q8C067_MOUSE Q8C067_MOUSE ------------------------------------------------------------ A2AET8_MOUSE A2AET8_MOUSE ------------------------------------------------------------ B7Z3Y5_HUMAN B7Z3Y5_HUMAN ------------------------------------------------------------ Q5JYJ2_HUMAN Q5JYJ2_HUMAN ------------RG---------------------------------------------- B7Z3Z2_HUMAN B7Z3Z2_HUMAN FLMQDIAFLSGGRGKDNAWIITFPENCNFRCIPEEVIAKVLTYLTSIARQNGSDSRFTII B2R9S6_HUMAN B2R9S6_HUMAN ------------------------------------------------------------ B7Z869_HUMAN B7Z869_HUMAN --MQDIAFLSGGRGKDNAWIITFPENCNFRCIPEEVIAKVLTYLTSIARQNGSDSRFTII B7ZAV1_HUMAN B7ZAV1_HUMAN --MQDIAFLSGGRGKDNAWIITFPENCNFRCIPEEVIAKVLTYLTSIARQNGSDSRFTII Q5JYJ7_HUMAN Q5JYJ7_HUMAN FLMQDIAFLSGGRGKDNAWIITFPENCNFRCIPEEVIAKVLTYLTSIARQNGSDSRFTII Q5JYJ5_HUMAN Q5JYJ5_HUMAN ------------------------------------------------------------ Q5JYJ6_HUMAN Q5JYJ6_HUMAN ------------------------------------------------------------ Q5JYJ3_HUMAN Q5JYJ3_HUMAN ------------------------------------------------------------ MCF2_HUMAN MCF2_HUMAN ------------------------------------------------------------ Q4S0P7_TETNG Q4S0P7_TETNG LMRQFAF-LSGGRGDNGSPIIVFPEFPTFGDITDREFHNVLTYLTSVPSLSSTDVGFIL- B8A4Q6_DANRE B8A4Q6_DANRE ------------------------------------------------------------ MCF2L_RAT MCF2L_RAT --------------------------------------------------QDAGIGFILV Q3UHQ9_MOUSE Q3UHQ9_MOUSE ----MAW-DSGVAGVHGSQVCC--------------QHMLTPSVSPCFSLQDAGIGFILV Q6PDM6_MOUSE Q6PDM6_MOUSE LKKRFAY-LSGGRGQDGSPVITFPDYPAFSEIPDKEFQNVMTYLTSIPSLQDAGIGFILV Q8C7Z1_MOUSE Q8C7Z1_MOUSE LKKRFAY-LSGGRGQDGSPVITFPDYPAFSEIPDKEFQNVMTYLTSIPSLQDAGIGFILV Q80U26_MOUSE Q80U26_MOUSE ------------------------------------------------------------ MCF2L_MOUSE MCF2L_MOUSE LKKRFAY-LSGGRGQDGSPVITFPDYPAFSEIPDKEFQNVMTYLTSIPSLQDAGIGFILV Q003U3_MOUSE Q003U3_MOUSE LKKRFAY-LSGGRGQDGSPVITFPDYPAFSEIPDKEFQNVMTYLTSIPSLQDAGIGFILV B5SNI0_OTOGA B5SNI0_OTOGA LKKRFAY-LSGGRGQDGSPVITFPDYPAFSEIPDKEFQNVMTYLTSVPSLQDAGIGFILV B3KT13_HUMAN B3KT13_HUMAN TTSESLTWTSTGTSDARTGVI----------------------------LQDAGIGFILV A9X169_PAPAN A9X169_PAPAN LKKRFAY-LSGGRGQDGSPVITFPDYPAFSEIPDKEFQNVMTYLTSIPSLQDTGIGFILV B1MTD7_CALMO B1MTD7_CALMO -MKQARA-SGGADATEGDG-------------------------SGGSSLQDAGIGFILV Q5REI0_PONAB Q5REI0_PONAB ----------------------------------------MTYLTSIPSLQDAGIGFILV B4DHD6_HUMAN B4DHD6_HUMAN LKKRFAY-LSGGRGQDGSPVITFPDYPAFSEIPDKEFQNVMTYLTSIPSLQDAGIGFILV B4DIL6_HUMAN B4DIL6_HUMAN LKKRFAY-LSGGRGQDGSPVITFPDYPAFSEIPDKEFQNVMTYLTSIPSLQDAGIGFILV B7Z9K4_HUMAN B7Z9K4_HUMAN LKKRFAY-LSGGRGQDGSPVITFPDYPAFSEIPDKEFQNVMTYLTSIPSLQDAGIGFILV MCF2L_HUMAN MCF2L_HUMAN LKKRFAY-LSGGRGQDGSPVITFPDYPAFSEIPDKEFQNVMTYLTSIPSLQDAGIGFILV A8MU87_HUMAN A8MU87_HUMAN ------------------------------------------------------------ B7ZBJ8_HUMAN B7ZBJ8_HUMAN ------------------------------------------------------------ B8A4Q9_DANRE B8A4Q9_DANRE LRKQFAF-LSGGRGQNGSPIIIFPEYPEFGELEEQEFHNVLTYLTSIPSLSSTGIGFILV Q4RY59_TETNG Q4RY59_TETNG LQKQFAI-LPGGRGINGNPVIIFPEFPAFGDLPQDEIQNVLGYLTSVPSIAASGVGFILV Q4SVF8_TETNG Q4SVF8_TETNG ------------------------------------------------------------ Q4RP67_TETNG Q4RP67_TETNG GHPGFSFPCPGGRGEDSSVIITLPECSAFSDIPEEALAKVFTYLTLIPRTRQPGVKFIII Q7ZZ90_DANRE Q7ZZ90_DANRE -----------GRGEDSSVIITLPECSAFSDIPEEALAKVLSYLTLIPRARQPGVKFIII MATCH CONSENSUS ????????????????????????????????????????????????????????????

MF2L2_HUMAN MF2L2_HUMAN IDRRRDKWSSVKASLTRIAVAFPGNLQLIFILRPSRFIQ-----RTFTDIGIKYYRNEFK A2AEU1_MOUSE A2AEU1_MOUSE LDRRLDTWASLKISLQKISASFPGSLHLVLVLRPTSFLQ-----RTFTDIGFRFSQEDFM Q8BLE2_MOUSE Q8BLE2_MOUSE LDRRLDTWASLKISLQKISASFPGSLHLVLVLRPTSFLQ-----RTFTDIGFRFSQEDFM Q99N72_MOUSE Q99N72_MOUSE --MAVANPPRGKMRFRRNAASFPGSLHLVLVLRPTSFLQ-----RTFTDIGFRFSQEDFM Q7TNJ5_MOUSE Q7TNJ5_MOUSE --MAVANPPRGKMRFRRNAASFPGSLHLVLVLRPTSFLQ-----RTFTDIGFRFSQEDFM Q8C067_MOUSE Q8C067_MOUSE --MAEANPPRGKMRFRRNAASFPGSLHLVLVLRPTSFLQ-----RTFTDIGFRFSQEDFM A2AET8_MOUSE A2AET8_MOUSE --MAEANPPRGKMRFRRNAASFPGSLHLVLVLRPTSFLQ-----RTFTDIGFRFSQEDFM B7Z3Y5_HUMAN B7Z3Y5_HUMAN --MAEANPRRGKMRFRRNAASFPGNLHLVLVLRPTSFLQ-----RTFTDIGFWFSQEDFM Q5JYJ2_HUMAN Q5JYJ2_HUMAN -----------KMRFRRNAASFPGNLHLVLVLRPTSFLQ-----RTFTDIGFWFSQEDFM B7Z3Z2_HUMAN B7Z3Z2_HUMAN LDRRLDTWSSLKISLQKISASFPGNLHLVLVLRPTSFLQ-----RTFTDIGFWFSQEDFM B2R9S6_HUMAN B2R9S6_HUMAN --MAEANPRRGKMRFRRNAASFPGNLHLVLVLRPTSFLQ-----RTFTDIGFWFSQEDFM B7Z869_HUMAN B7Z869_HUMAN LDRRLDTWSSLKISLQKISASFPGNLHLVLVLRPTSFLQ-----RTFTDIGFWFSQEDFM B7ZAV1_HUMAN B7ZAV1_HUMAN LDRRLDTWSSLKISLQKISASFPGNLHLVLVLRPTSFLQ-----RTFTDIGFWFSQEDFM Q5JYJ7_HUMAN Q5JYJ7_HUMAN LDRRLDTWSSLKISLQKISASFPGNLHLVLVLRPTSFLQ-----RTFTDIGFWFSQEDFM Q5JYJ5_HUMAN Q5JYJ5_HUMAN ------------------------------------------------------------ Q5JYJ6_HUMAN Q5JYJ6_HUMAN ------------------------------------------------------------ Q5JYJ3_HUMAN Q5JYJ3_HUMAN --MAEANPRRGKMRFRRNAASFPGNLHLVLVLRPTSFLQ-----RTFTDIGFWFSQEDFM MCF2_HUMAN MCF2_HUMAN --MAEANPRRGKMRFRRNAASFPGNLHLVLVLRPTSFLQ-----RTFTDIGFWFSQEDFM Q4S0P7_TETNG Q4S0P7_TETNG -------------------GSFPGNLELVLVLRPTTLLQ-----RTLSDIFFKFNKDE-- B8A4Q6_DANRE B8A4Q6_DANRE ------------------------------------------------------------ MCF2L_RAT MCF2L_RAT IDRRQDKWTSVKASVLRIAASFPANLQLVLVLRPTGFFQ-----RTLSDIAFKFNRDEFK Q3UHQ9_MOUSE Q3UHQ9_MOUSE IDRRQDKWTSVKASVLRIAASFPANLQLVLVLRPTGFFQ-----RTLSDIAFKFNRDEFK Q6PDM6_MOUSE Q6PDM6_MOUSE IDRRQDKWTSVKASVLRIAASFPANLQLVLVLRPTGFFQ-----RTLSDIAFKFNRDEFK Q8C7Z1_MOUSE Q8C7Z1_MOUSE IDRRQDKWTSVKASVLRIAASFPANLQLVLVLRPTGFFQ-----RTLSDIAFKFNRDEFK Q80U26_MOUSE Q80U26_MOUSE ------------------------------------------------------------ MCF2L_MOUSE MCF2L_MOUSE IDRRQDKWTSVKASVLRIAASFPANLQLVLVLRPTGFFQ-----RTLSDIAFKFNRDEFK Q003U3_MOUSE Q003U3_MOUSE IDRRQDKWTSVKASVLRIAASFPANLQLVLVLRPTGFFQ-----RTLSDIAFKFNRDEFK B5SNI0_OTOGA B5SNI0_OTOGA IDRRRDKWTSVKASVLRIAASFPANLQLVLVLRPTGFFQ-----RTLSDIAFKFNRDDFK B3KT13_HUMAN B3KT13_HUMAN IDRRRDKWTSVKASVLRIAASFPANLQLVLVLRPTGFFQ-----RTLSDIAFKFNRDDFK A9X169_PAPAN A9X169_PAPAN IDRRRDKWTSVKASVLRIAASFPANLQLVLVLRPTGFFQ-----RTLSDIAFKFNRDDFK B1MTD7_CALMO B1MTD7_CALMO IDRRRDKWTSVKASVLRIAASFPANLQLVLVLRPTGFFQ-----RTLSDIAFKFNRDDFK Q5REI0_PONAB Q5REI0_PONAB IDRRRDKWTSVKASVLRIAASFPANLQLVLVLRPTGFFQ-----RTLSDIAFKFNRDDFK B4DHD6_HUMAN B4DHD6_HUMAN IDRRRDKWTSVKASVLRIAASFPANLQLVLVLRPTGFFQ-----RTLSDIAFKFNRDDFK B4DIL6_HUMAN B4DIL6_HUMAN IDRRRDKWTSVKASVLRIAASFPANLQLVLVLRPTGFFQ-----RTLSDIAFKFNRDDFK B7Z9K4_HUMAN B7Z9K4_HUMAN IDRRRDKWTSVKASVLRIAASFPANLQLVLVLRPTGFFQ-----RTLSDIAFKFNRDDFK MCF2L_HUMAN MCF2L_HUMAN IDRRRDKWTSVKASVLRIAASFPANLQLVLVLRPTGFFQ-----RTLSDIAFKFNRDDFK A8MU87_HUMAN A8MU87_HUMAN ------------------------------------------------------------ B7ZBJ8_HUMAN B7ZBJ8_HUMAN ------------------------------------------------------------ B8A4Q9_DANRE B8A4Q9_DANRE IDRRQDRWASVKGTLLRIAGSFPGNLQLVLVLRPTTLFQ-----RTISDILFKFNKDDFK Q4RY59_TETNG Q4RY59_TETNG IDRRQDRWAAVKATLHRIAGSFPGNLHLVLVLRPSTFLQ-----RTLSDVLFK--KDEFK Q4SVF8_TETNG Q4SVF8_TETNG --------------------SFPGNLHLILVLRPSGLSSSAPSPSSSTDLGFRFSQDDFL Q4RP67_TETNG Q4RP67_TETNG LDRRLDTWASIKTALSRIAASFPGNLHLVLVLRPTSFFH-----RTVTDIGFRFSQEDFM Q7ZZ90_DANRE Q7ZZ90_DANRE LDRRLDTWTSIKTALARIAASFPGNLHLVLVLRPTSFFQ-----RTVTDLGFRFSQEDFM MATCH CONSENSUS ???????????K????????SFP??L?LVLVLRP????Q?????RT??D??F?F????F?

MF2L2_HUMAN MF2L2_HUMAN TKVP-------------------------------------------------------- A2AEU1_MOUSE A2AEU1_MOUSE LKLP-------------------------------------------------------- Q8BLE2_MOUSE Q8BLE2_MOUSE LKLP-------------------------------------------------------- Q99N72_MOUSE Q99N72_MOUSE LKLP-------------------------------------------------------- Q7TNJ5_MOUSE Q7TNJ5_MOUSE LKLP-------------------------------------------------------- Q8C067_MOUSE Q8C067_MOUSE LKLP-------------------------------------------------------- A2AET8_MOUSE A2AET8_MOUSE LKLP-------------------------------------------------------- B7Z3Y5_HUMAN B7Z3Y5_HUMAN LKLP-------------------------------------------------------- Q5JYJ2_HUMAN Q5JYJ2_HUMAN LKLP-------------------------------------------------------- B7Z3Z2_HUMAN B7Z3Z2_HUMAN LKLP-------------------------------------------------------- B2R9S6_HUMAN B2R9S6_HUMAN LKLP-------------------------------------------------------- B7Z869_HUMAN B7Z869_HUMAN LKLP-------------------------------------------------------- B7ZAV1_HUMAN B7ZAV1_HUMAN LKLP-------------------------------------------------------- Q5JYJ7_HUMAN Q5JYJ7_HUMAN LKLP-------------------------------------------------------- Q5JYJ5_HUMAN Q5JYJ5_HUMAN ------------------------------------------------------------ Q5JYJ6_HUMAN Q5JYJ6_HUMAN ------------------------------------------------------------ Q5JYJ3_HUMAN Q5JYJ3_HUMAN LKLP-------------------------------------------------------- MCF2_HUMAN MCF2_HUMAN LKLP-------------------------------------------------------- Q4S0P7_TETNG Q4S0P7_TETNG ------------------------------------------------------------ B8A4Q6_DANRE B8A4Q6_DANRE ------------------------------------------------------------ MCF2L_RAT MCF2L_RAT MKVP-------------------------------------------------------- Q3UHQ9_MOUSE Q3UHQ9_MOUSE MKVP-------------------------------------------------------- Q6PDM6_MOUSE Q6PDM6_MOUSE MKVP-------------------------------------------------------- Q8C7Z1_MOUSE Q8C7Z1_MOUSE MKVP-------------------------------------------------------- Q80U26_MOUSE Q80U26_MOUSE ------------------------------------------------------------ MCF2L_MOUSE MCF2L_MOUSE MKVP-------------------------------------------------------- Q003U3_MOUSE Q003U3_MOUSE MKVP-------------------------------------------------------- B5SNI0_OTOGA B5SNI0_OTOGA MKVP-------------------------------------------------------- B3KT13_HUMAN B3KT13_HUMAN MKVP-------------------------------------------------------- A9X169_PAPAN A9X169_PAPAN MKVP-------------------------------------------------------- B1MTD7_CALMO B1MTD7_CALMO MKVP-------------------------------------------------------- Q5REI0_PONAB Q5REI0_PONAB MKVP-------------------------------------------------------- B4DHD6_HUMAN B4DHD6_HUMAN MKVP-------------------------------------------------------- B4DIL6_HUMAN B4DIL6_HUMAN MKVP-------------------------------------------------------- B7Z9K4_HUMAN B7Z9K4_HUMAN MKVP-------------------------------------------------------- MCF2L_HUMAN MCF2L_HUMAN MKVP-------------------------------------------------------- A8MU87_HUMAN A8MU87_HUMAN ------------------------------------------------------------ B7ZBJ8_HUMAN B7ZBJ8_HUMAN ------------------------------------------------------------ B8A4Q9_DANRE B8A4Q9_DANRE MKVP-------------------------------------------------------- Q4RY59_TETNG Q4RY59_TETNG MK---------------------------------------------------------- Q4SVF8_TETNG Q4SVF8_TETNG LKMP-------------------------------------------------------- Q4RP67_TETNG Q4RP67_TETNG LKMPVRKLPLKRHTCPPSQQGTRPHSISELTEEHRPDIAANIIIKVTSYCMSEVMIGFYP Q7ZZ90_DANRE Q7ZZ90_DANRE LKMP-------------------------------------------------------- MATCH CONSENSUS ?K?P????????????????????????????????????????????????????????

MF2L2_HUMAN MF2L2_HUMAN ---------------------------IIMVNSVSDLHGYIDKSQLTRELGGTLEYRHGQ A2AEU1_MOUSE A2AEU1_MOUSE ---------------------------VVMLSSVSDLLTYIDDKQLTPELGGTLQYCHSE Q8BLE2_MOUSE Q8BLE2_MOUSE ---------------------------VVMLSSVSDLLTYIDDKQLTPELGGTLQYCHSE Q99N72_MOUSE Q99N72_MOUSE ---------------------------VVMLSSVSDLLTYIDDKQLTPELGGTLQYCHSE Q7TNJ5_MOUSE Q7TNJ5_MOUSE ---------------------------VVMLSSVSDLLTYIDDKQLTPELGGTLQYCHSE Q8C067_MOUSE Q8C067_MOUSE ---------------------------VVMLSSVSDLLTYIDDKQLTPELGGTLQYCHSE A2AET8_MOUSE A2AET8_MOUSE ---------------------------VVMLSSVSDLLTYIDDKQLTPELGGTLQYCHSE B7Z3Y5_HUMAN B7Z3Y5_HUMAN ------------------------------------------------------------ Q5JYJ2_HUMAN Q5JYJ2_HUMAN ---------------------------VVMLSSVSDLLTYIDDKQLTPELGGTLQYCHSE B7Z3Z2_HUMAN B7Z3Z2_HUMAN ---------------------------VVMLSSVSDLLTYIDDKQLTPELGGTLQYCHSE B2R9S6_HUMAN B2R9S6_HUMAN ---------------------------VVMLSSVSDLLTYIDDKQLTPELGGTLQYCHSE B7Z869_HUMAN B7Z869_HUMAN ---------------------------VVMLSSVSDLLTYIDDKQLTPELGGTLQYCHSE B7ZAV1_HUMAN B7ZAV1_HUMAN ---------------------------VVMLSSVSDLLTYIDDKQLTPELGGTLQYCHSE Q5JYJ7_HUMAN Q5JYJ7_HUMAN ---------------------------VVMLSSVSDLLTYIDDKQLTPELGGTLQYCHSE Q5JYJ5_HUMAN Q5JYJ5_HUMAN ------------------------------------------------------------ Q5JYJ6_HUMAN Q5JYJ6_HUMAN ------------------------------------------------------------ Q5JYJ3_HUMAN Q5JYJ3_HUMAN ---------------------------VVMLSSVSDLLTYIDDKQLTPELGGTLQYCHSE MCF2_HUMAN MCF2_HUMAN ---------------------------VVMLSSVSDLLTYIDDKQLTPELGGTLQYCHSE Q4S0P7_TETNG Q4S0P7_TETNG ---------------------------VIMLSSIAELHSYIDRTQLTEDLGGTQEYCHDK B8A4Q6_DANRE B8A4Q6_DANRE ------------------------------------------------------------ MCF2L_RAT MCF2L_RAT ---------------------------VMMLSSVPELHGYIDKSQLTEDLGGTLDYCHSR Q3UHQ9_MOUSE Q3UHQ9_MOUSE ---------------------------VMMLSSVPELHGYIDKSQLTEDLGGTLDYCHSR Q6PDM6_MOUSE Q6PDM6_MOUSE ---------------------------VMMLSSVPELHGYIDKSQLTEDLGGTLDYCHSR Q8C7Z1_MOUSE Q8C7Z1_MOUSE ---------------------------VMMLSSVPELHGYIDKSQLTEDLGGTLDYCHSR Q80U26_MOUSE Q80U26_MOUSE ------------------------------------------------------------ MCF2L_MOUSE MCF2L_MOUSE ---------------------------VMMLSSVPELHGYIDKSQLTEDLGGTLDYCHSR Q003U3_MOUSE Q003U3_MOUSE ---------------------------VMMLSSVPELHGYIDKSQLTEDLGGTLDYCHSR B5SNI0_OTOGA B5SNI0_OTOGA ---------------------------VIMLSSVPDLHGYIDKSQLTEDLGGTLDYCHTR B3KT13_HUMAN B3KT13_HUMAN ---------------------------VIMLSSVPDLHGYIDKSQLTEDLGGTLDYCHSR A9X169_PAPAN A9X169_PAPAN ---------------------------VIMLSSVPDLHGYIDKSQLTEDLGGTLDYCHSR B1MTD7_CALMO B1MTD7_CALMO ---------------------------VIMLSSVPDLHSYIDKSQLTEDLGGTLDYCHSR Q5REI0_PONAB Q5REI0_PONAB ---------------------------VIMLSSVPDLHGYIDKSQLTEDLGGTLDYCHSR B4DHD6_HUMAN B4DHD6_HUMAN ---------------------------VIMLSSVPDLHGYIDKSQLTEDLGGTLDYCHSR B4DIL6_HUMAN B4DIL6_HUMAN ---------------------------VIMLSSVPDLHGYIDKSQLTEDLGGTLDYCHSR B7Z9K4_HUMAN B7Z9K4_HUMAN ---------------------------VIMLSSVPDLHGYIDKSQLTEDLGGTLDYCHSR MCF2L_HUMAN MCF2L_HUMAN ---------------------------VIMLSSVPDLHGYIDKSQLTEDLGGTLDYCHSR A8MU87_HUMAN A8MU87_HUMAN ------------------------------------------------------------ B7ZBJ8_HUMAN B7ZBJ8_HUMAN ------------------------------------------------------------ B8A4Q9_DANRE B8A4Q9_DANRE ---------------------------VIMLSSVTELHSYIDRSQLTQELGGTQEYCHEK Q4RY59_TETNG Q4RY59_TETNG ---------------------------VVMLSSVTELHAYIDPGQLTREVGGTQEYCHES Q4SVF8_TETNG Q4SVF8_TETNG ----------------------------------------VRKSAGASDFRAKVEYCQSD Q4RP67_TETNG Q4RP67_TETNG GNHHHHHYKIKIRRQILTLDAFCLPLQVVMLSSVTDLLRYIDENQLTSEFGGTLDYCHSD Q7ZZ90_DANRE Q7ZZ90_DANRE ---------------------------VVMLSSVTDLLRYIDENQLTSEFGGTLDYCHSD MATCH CONSENSUS ?????????????????????????????M??S???L??YID??QLT???GGT??YCH??

MF2L2_HUMAN MF2L2_HUMAN WVNHRTAIENFALTLKTTAQMLQTFGSCLATAELPRSMLSTEDLLMSHTRQRDKLQ---D A2AEU1_MOUSE A2AEU1_MOUSE WIIFRNAIEKFAVTVKEMAQMLQSFGTELAETELPQDILSIEEILAGRAERYHLLK---N Q8BLE2_MOUSE Q8BLE2_MOUSE WIIFRNAIEKFAVTVKEMAQMLQSFGTELAETELPQDILSIEEILAGRAERYHLLK---N Q99N72_MOUSE Q99N72_MOUSE WIIFRNAIEKFAVTVKEMAQMLQSFGTELAETELPQDILSIEEILAGRAERYHLLK---N Q7TNJ5_MOUSE Q7TNJ5_MOUSE WIIFRNAIEKFAVTVKEMAQMLQSFGTELAETELPQDILSIEEILAGRAERYHLLK---N Q8C067_MOUSE Q8C067_MOUSE WIIFRNAIEKFAVTVKEMAQMLQSFGTELAETELPQDILSIEEILAGRAERYHLLK---N A2AET8_MOUSE A2AET8_MOUSE WIIFRNAIEKFAVTVKEMAQMLQSFGTELAETELPQDILSIEEILAGRAERYHLLK---N B7Z3Y5_HUMAN B7Z3Y5_HUMAN ------AIENFALTVKEMAQMLQSFGTELAETELPDDIPSIEEILAIRAERYHLLK---N Q5JYJ2_HUMAN Q5JYJ2_HUMAN WIIFRNAIENFALTVKEMAQMLQSFGTELAETELPDDIPSIEEILAIRAERYHLLK---N B7Z3Z2_HUMAN B7Z3Z2_HUMAN WIIFRNAIENFALTVKEMAQMLQSFGTELAETELPDDIPSIEEILAIRAERYHLLK---N B2R9S6_HUMAN B2R9S6_HUMAN WIIFRNAIENFALTVKEMAQMLQSFGTELAETELPDDIPSIEEILAIRAERYHLLK---N B7Z869_HUMAN B7Z869_HUMAN WIIFRNAIENFALTVKEMAQMLQSFGTELAETELPDDIPSIEEILAIRAERYHLLK---N B7ZAV1_HUMAN B7ZAV1_HUMAN WIIFRNAIENFALTVKEMAQMLQSFGTELAETELPDDIPSIEEILAIRAERYHLLK---N Q5JYJ7_HUMAN Q5JYJ7_HUMAN WIIFRNAIENFALTVKEMAQMLQSFGTELAETELPDDIPSIEEILAIRAERYHLLK---N Q5JYJ5_HUMAN Q5JYJ5_HUMAN ------------------------------------------------------------ Q5JYJ6_HUMAN Q5JYJ6_HUMAN ------------------------------------------------------------ Q5JYJ3_HUMAN Q5JYJ3_HUMAN WIIFRNAIENFALTVKEMAQMLQSFGTELAETELPDDIPSIEEILAIRAERYHLLK---N MCF2_HUMAN MCF2_HUMAN WIIFRNAIENFALTVKEMAQMLQSFGTELAETELPDDIPSIEEILAIRAERYHLLK---N Q4S0P7_TETNG Q4S0P7_TETNG WISHRTAIEGFALMVKKTAQTLQSFGTELAETELPSEVQATTNLLSTHTDKKDQMK---E B8A4Q6_DANRE B8A4Q6_DANRE ------------------------------------------------------------ MCF2L_RAT MCF2L_RAT WLCHRTAIESFALMVKQTAQMLQAFGTELAETELPNDVQSTSLVLSAHTEKKAKVK---E Q3UHQ9_MOUSE Q3UHQ9_MOUSE WLCHRTAIESFALMVKQTAQMLQAFGTELAETELPNDVQSTSLVLSAHTEKKAKVK---E Q6PDM6_MOUSE Q6PDM6_MOUSE WLCHRTAIESFALMVKQTAQMLQAFGTELAETELPNDVQSTSLVLSAHTEKKAKVK---E Q8C7Z1_MOUSE Q8C7Z1_MOUSE WLCHRTAIESFALMVKQTAQMLQAFGTELAETELPNDVQSTSLVLSAHTEKKAKVK---E Q80U26_MOUSE Q80U26_MOUSE ------------------------------------------------------------ MCF2L_MOUSE MCF2L_MOUSE WLCHRTAIESFALMVKQTAQMLQAFGTELAETELPNDVQSTSLVLSAHTEKKAKVK---E Q003U3_MOUSE Q003U3_MOUSE WLCHRTAIESFALMVKQTAQMLQAFGTELAETELPNDVQSTSLVLSAHTEKKAKVK---E B5SNI0_OTOGA B5SNI0_OTOGA WLCHRTAIESFALMVKQTAQMLQSFGTELAETELPNDIQSTSSVLCAHTEKKDKVK---E B3KT13_HUMAN B3KT13_HUMAN WLCQRTAIESFALMVKQTAQMLQSFGTELAETELPNDVQSTSSVLCAHTEKKDKAK---E A9X169_PAPAN A9X169_PAPAN WLCQRTAIESFALMVKQTAQMLQSFGTELAETELPNDVQSTSSVLCAHTEKKDKAK---E B1MTD7_CALMO B1MTD7_CALMO WLCQRTAIESFALMVKQTAQMLQSFGTELAETELPNDVQSTSSVLCAHTEKKDKAK---E Q5REI0_PONAB Q5REI0_PONAB WLCQRTAIESFALMVKQTAQMLQSFGTELAETELPNDVQSTSSVLCAHTEKKDKAK---E B4DHD6_HUMAN B4DHD6_HUMAN WLCQRTAIESFALMVKQTAQMLQSFGTELAETELPNDVQSTSSVLCAHTEKKDKAK---E B4DIL6_HUMAN B4DIL6_HUMAN WLCQRTAIESFALMVKQTAQMLQSFGTELAETELPNDVQSTSSVLCAHTEKKDKAK---E B7Z9K4_HUMAN B7Z9K4_HUMAN WLCQRTAIESFALMVKQTAQMLQSFGTELAETELPNDVQSTSSVLCAHTEKKDKAK---E MCF2L_HUMAN MCF2L_HUMAN WLCQRTAIESFALMVKQTAQMLQSFGTELAETELPNDVQSTSSVLCAHTEKKDKAK---E A8MU87_HUMAN A8MU87_HUMAN ------------------------------------------------------------ B7ZBJ8_HUMAN B7ZBJ8_HUMAN ------------------------------------------------------------ B8A4Q9_DANRE B8A4Q9_DANRE WISHRTAIEGFALMVKKTAQTLQSFGTELAETELPNDVEATSNLLTVHTEKKDKMK---E Q4RY59_TETNG Q4RY59_TETNG WISHRTAIEAFALMVKTTAQTLQAFGTELAETELPNDAEATTNLLHTHTQKKEKMK---E Q4SVF8_TETNG Q4SVF8_TETNG WILLRTAIETFAVTVKETAQVLQAFGSELSDTELPDEANAIEFLLHSHSHRYRQMKVCPS Q4RP67_TETNG Q4RP67_TETNG WMFLRTAIESFAVTVKDIAQMLQSFGTELAETELPDDGRDTEHLLETHTAKYRKLK---D Q7ZZ90_DANRE Q7ZZ90_DANRE WIVLRTAIESFAVMVKDIAQMLQAFGTELAETQLSEECSAIEFLLLSHTEKYRRLK---D MATCH CONSENSUS W???R?AIE?FA??VK??AQ?LQ?FGTELAETELP?????????L??????????K????

MF2L2_HUMAN MF2L2_HUMAN ELKLLGKQGTTLLSCI------QEPATKCPNSK---LNLNQLE----------------- A2AEU1_MOUSE A2AEU1_MOUSE DLTAVTKEGKVLLMNL------QVPATEETVSSSLECTQHING----------------- Q8BLE2_MOUSE Q8BLE2_MOUSE DLTAVTKEGKVLLMNL------QVPATEETVSSSLECTQHING----------------- Q99N72_MOUSE Q99N72_MOUSE DLTAVTKEGKVLLMNL------QVPATEETVSSSLECTQHING----------------- Q7TNJ5_MOUSE Q7TNJ5_MOUSE DLTAVTKEGKVLLMNL------QVPATEETVSSSLECTQHING----------------- Q8C067_MOUSE Q8C067_MOUSE DLTAVTKEGKVLLMNL------QVPATEETVSSSLECTQHING----------------- A2AET8_MOUSE A2AET8_MOUSE DLTAVTKEGKVLLMNL------QVPATEETVSSSLECTQHING----------------- B7Z3Y5_HUMAN B7Z3Y5_HUMAN DITAVTKEGKILLTNL------EVPDTEGAVSSRLESHRQISG----------------- Q5JYJ2_HUMAN Q5JYJ2_HUMAN DITAVTKEGKILLTNL------EVPDTEGAVSSRLECHRQISG----------------- B7Z3Z2_HUMAN B7Z3Z2_HUMAN DITAVTKEGKILLTNL------EVPDTEGAVSSRLECHRQISG----------------- B2R9S6_HUMAN B2R9S6_HUMAN DITAVTKEGKILLTNL------EVPDTEGAVSSRLECHRQISG----------------- B7Z869_HUMAN B7Z869_HUMAN DITAVTKEGKILLTNL------EVPDTEGAVSSRLECHRQISG----------------- B7ZAV1_HUMAN B7ZAV1_HUMAN DITAVTKEGKILLTNL------EVPDTEGAVSSRLECHRQISG----------------- Q5JYJ7_HUMAN Q5JYJ7_HUMAN DITAVTKEGKILLTNL------EVPDTEGAVSSRLECHRQISG----------------- Q5JYJ5_HUMAN Q5JYJ5_HUMAN ------------------------------------------------------------ Q5JYJ6_HUMAN Q5JYJ6_HUMAN ------------------------------------------------------------ Q5JYJ3_HUMAN Q5JYJ3_HUMAN DITAVTKEGKILLTNL------EVPDTEGAVSSRLECHRQISG----------------- MCF2_HUMAN MCF2_HUMAN DITAVTKEGKILLTNL------EVPDTEGAVSSRLECHRQISG----------------- Q4S0P7_TETNG Q4S0P7_TETNG DLLVALGQGSRLLESI------NEPVVRDPDHN---MNQDELE----------------- B8A4Q6_DANRE B8A4Q6_DANRE ------------------------------------------------------------ MCF2L_RAT MCF2L_RAT DLQLALTEGNSILESL------REPLAESIVHS---VNQDQLD----------------- Q3UHQ9_MOUSE Q3UHQ9_MOUSE DLQLALKEGNSILESL------REPLAESAAHS---VNQDQLD----------------- Q6PDM6_MOUSE Q6PDM6_MOUSE DLQLALKEGNSILESL------REPLAESAAHS---VNQDQLD----------------- Q8C7Z1_MOUSE Q8C7Z1_MOUSE DLQLALKEGNSILESL------REPLAESAAHS---VNQDQLD----------------- Q80U26_MOUSE Q80U26_MOUSE ------------------------------------------------------------ MCF2L_MOUSE MCF2L_MOUSE DLQLALKEGNSILESL------REPLAESAAHS---VNQDQLD----------------- Q003U3_MOUSE Q003U3_MOUSE DLQLALKEGNSILESL------REPLAESAAHS---VNQDQLD----------------- B5SNI0_OTOGA B5SNI0_OTOGA DLRLALEEGRSVLESL------RTPLAEGLEHS---VNQDQLD----------------- B3KT13_HUMAN B3KT13_HUMAN DLRLALKEGHSVLESL------RELQAEGSEPS---VNQDQLD----------------- A9X169_PAPAN A9X169_PAPAN DLRLALKEGHSVLESL------GELQAEGSEPG---VNQDQLD----------------- B1MTD7_CALMO B1MTD7_CALMO DLRLALKEGRSILESL------KEPQAEGSEPG---VNQDQLD----------------- Q5REI0_PONAB Q5REI0_PONAB DLRLALKEGHSVLESL------RELQAEGSESS---VNQDQLD----------------- B4DHD6_HUMAN B4DHD6_HUMAN DLRLALKEGHSVLESL------RELQAEGSEPS---VNQDQLD----------------- B4DIL6_HUMAN B4DIL6_HUMAN DLRLALKEGHSVLESL------RELQAEGSEPS---VNQDQLD----------------- B7Z9K4_HUMAN B7Z9K4_HUMAN DLRLALKEGHSVLESL------RELQAEGSEPS---VNQDQLD----------------- MCF2L_HUMAN MCF2L_HUMAN DLRLALKEGHSVLESL------RELQAEGSEPS---VNQDQLD----------------- A8MU87_HUMAN A8MU87_HUMAN ------------------------------------------------------------ B7ZBJ8_HUMAN B7ZBJ8_HUMAN ------------------------------------------------------------ B8A4Q9_DANRE B8A4Q9_DANRE DLRIALCQGGRLLESI------NEPLVKDPDYS---MNHDELE----------------- Q4RY59_TETNG Q4RY59_TETNG DLQVALSQGGRLLDCI------KEPLRTDPEYN---MTHDEVE----------------- Q4SVF8_TETNG Q4SVF8_TETNG SCSPVSAAGPHLFFLFVCFFSGRHPEGAERRSPAAHQPGDRQGFQEGRGGGEGPAGRHGH Q4RP67_TETNG Q4RP67_TETNG AIISVSKDGHHLLLSL------ETSGKEEDAQWDVRM----------------------- Q7ZZ90_DANRE Q7ZZ90_DANRE AIRSVMREGRQLLSNL------ETSRKEGDVDT----RWDITQ----------------- MATCH CONSENSUS ????????G???L???????????????????????????????????????????????

MF2L2_HUMAN MF2L2_HUMAN ------------NVTTM-----ERLLVQLDETEKAFSHFWSEHHLKLNQCLQLQHFEHDF A2AEU1_MOUSE A2AEU1_MOUSE ------------DWQTI-----KKLLAQVHDMETAFDGFWEKHQLKMEQYLQLWKFEQDF Q8BLE2_MOUSE Q8BLE2_MOUSE ------------DWQTI-----KKLLAQVHDMETAFDGFWEKHQLKMEQYLQLWKFEQDF Q99N72_MOUSE Q99N72_MOUSE ------------DWQTI-----KKLLAQVHDMETAFDGFWEKHQLKMEQYLQLWKFEQDF Q7TNJ5_MOUSE Q7TNJ5_MOUSE ------------DWQTI-----KKLLAQVHDMETAFDGFWEKHQLKMEQYLQLWKFEQDF Q8C067_MOUSE Q8C067_MOUSE ------------DWQTI-----KKLLAQVHDMETAFDGFWEKHQLKMEQYLQLWKFEQDF A2AET8_MOUSE A2AET8_MOUSE ------------DWQTI-----KKLLAQVHDMETAFDGFWEKHQLKMEQYLQLWKFEQDF B7Z3Y5_HUMAN B7Z3Y5_HUMAN ------------DWQTI-----NKLLTQVHDMETAFDGFWEKHQLKMEQYLQLWKFEQDF Q5JYJ2_HUMAN Q5JYJ2_HUMAN ------------DWQTI-----NKLLTQVHDMETAFDGFWEKHQLKMEQYLQLWKFEQDF B7Z3Z2_HUMAN B7Z3Z2_HUMAN ------------DWQTI-----NKLLTQVHDMETAFDGFWEKHQLKMEQYLQLWKFEQDF B2R9S6_HUMAN B2R9S6_HUMAN ------------DWQTI-----NKLLTQVHDMETAFDGFWEKHQLKMEQYLQLWKFEQDF B7Z869_HUMAN B7Z869_HUMAN ------------DWQTI-----NKLLTQVHDMETAFDGFWEKHQLKMEQYLQLWKFEQDF B7ZAV1_HUMAN B7ZAV1_HUMAN ------------DWQTI-----NKLLTQVHDMETAFDGFWEKHQLKMEQYLQLWKFEQDF Q5JYJ7_HUMAN Q5JYJ7_HUMAN ------------DWQTI-----NKLLTQVHDMETAFDGFWEKHQLKMEQYLQLWKFEQDF Q5JYJ5_HUMAN Q5JYJ5_HUMAN ------------------------------------------------------------ Q5JYJ6_HUMAN Q5JYJ6_HUMAN ------------------------------------------------------------ Q5JYJ3_HUMAN Q5JYJ3_HUMAN ------------DWQTI-----NKLLTQVHDMETAFDGFWEKHQLKMEQYLQLWKFEQDF MCF2_HUMAN MCF2_HUMAN ------------DWQTI-----NKLLTQVHDMETAFDGFWEKHQLKMEQYLQLWKFEQDF Q4S0P7_TETNG Q4S0P7_TETNG ------------NMATV-----QRLLSQLDETERAFDEFWVRHQTKLEQCLQLRHFEHNY B8A4Q6_DANRE B8A4Q6_DANRE ------------------------------------------------------------ MCF2L_RAT MCF2L_RAT ------------NQATV-----KRLLTQLNETEAAFDEFWAKHQQKLEQCLQLRHFEQGF Q3UHQ9_MOUSE Q3UHQ9_MOUSE ------------NQATV-----QRLLAQLNETEAAFDEFWAKHQQKLEQCLQLRHFEQGF Q6PDM6_MOUSE Q6PDM6_MOUSE ------------NQATV-----QRLLAQLNETEAAFDEFWAKHQQKLEQCLQLRHFEQGF Q8C7Z1_MOUSE Q8C7Z1_MOUSE ------------NQATV-----QRLLAQLNETEAAFDEFWAKHQQKLEQCLQLRHFEQGF Q80U26_MOUSE Q80U26_MOUSE ------------------------------------------------------------ MCF2L_MOUSE MCF2L_MOUSE ------------NQATV-----QRLLAQLNETEAAFDEFWAKHQQKLEQCLQLRHFEQGF Q003U3_MOUSE Q003U3_MOUSE ------------NQATV-----QRLLAQLNETEAAFDEFWAKHQQKLEQCLQLRHFEQGF B5SNI0_OTOGA B5SNI0_OTOGA ------------NQTTV-----QRLLAQLNETEAAFDEFWAKHQQKLQQCLQLRHFEQGF B3KT13_HUMAN B3KT13_HUMAN ------------NQATV-----QRLLAQLNETEAAFDEFWAKHQQKLEQCLLLRHFEQGF A9X169_PAPAN A9X169_PAPAN ------------NRATV-----QRLLAQLNETEAAFDEFWAKHQQKLEQCLQLRHFEQGF B1MTD7_CALMO B1MTD7_CALMO ------------NQATV-----QRLLAQLNETEAAFDEFWAKHQQKLEQCLQLRHFEQGF Q5REI0_PONAB Q5REI0_PONAB ------------NQATV-----QRLLAQLNETEAAFDEFWAKHQQKLEQCLQLRHFEQGF B4DHD6_HUMAN B4DHD6_HUMAN ------------NQATV-----QRLLAQLNETEAAFDEFWAKHQQKLEQCLQLRHFEQGF B4DIL6_HUMAN B4DIL6_HUMAN ------------NQATV-----QRLLAQLNETEAAFDEFWAKHQQKLEQCLQLRHFEQGF B7Z9K4_HUMAN B7Z9K4_HUMAN ------------NQATV-----QRLLAQLNETEAAFDEFWAKHQQKLEQCLQLRHFEQGF MCF2L_HUMAN MCF2L_HUMAN ------------NQATV-----QRLLAQLNETEAAFDEFWAKHQQKLEQCLQLRHFEQGF A8MU87_HUMAN A8MU87_HUMAN ------------------------------------------------------------ B7ZBJ8_HUMAN B7ZBJ8_HUMAN ------------------------------------------------------------ B8A4Q9_DANRE B8A4Q9_DANRE ------------NLATV-----QRLLGQLDETETAFDDFWDKHQTKLEQCLQLRHFEQNF Q4RY59_TETNG Q4RY59_TETNG ------------NLATV-----QRLLGQLDETETAFDDFWERHCTKLEQCLQLRYFELQF Q4SVF8_TETNG Q4SVF8_TETNG RPKVPFDPSRRLTWERVSRSASSRLLGQLRDMEEAFDGFFEKHHLKLQQYLQLLQYEISF Q4RP67_TETNG Q4RP67_TETNG ------------DWETV-----QRLYTQLRDMELAFDGFFEKHRLKFHQYLQLLRYEQRF Q7ZZ90_DANRE Q7ZZ90_DANRE ------------DWDTM-----QRLLAQLTDMEIAFDGFFDKHHLKLQQYLQLLRYEHSF MATCH CONSENSUS ???????????????T????????LL?Q????E?AFD?F???H??K??Q?LQL???E??F

MF2L2_HUMAN MF2L2_HUMAN CKAKLALDNLLEEQAEFTGIGDSVMHVEQILKEHKKLEEKSQEPLEKAQLLALVGDQLIQ A2AEU1_MOUSE A2AEU1_MOUSE QEAVTQVEFLLSQQRELGDITGNLAQVKQRLKKLEILDDKSQELLTKARIVILRGHKLAS Q8BLE2_MOUSE Q8BLE2_MOUSE QEAVTQVEFLLSQQRELGDITGNLAQVKQRLKKLEILDDKSQELLTKARIVILRGHKLAS Q99N72_MOUSE Q99N72_MOUSE QEAVTQVEFLLSQQRELGDITGNLAQVKQRLKKLEILDDKSQELLTKARIVILRGHKLAS Q7TNJ5_MOUSE Q7TNJ5_MOUSE QEAVTQVEFLLSQQRELGDITGNLAQVKQRLKKLEILDDKSQELLTKARIVILRGHKLAS Q8C067_MOUSE Q8C067_MOUSE QEAVTQVEFLLSQQRELGDITGNLAQVKQRLKKLEILDDKSQELLTKARIVILRGHKLAS A2AET8_MOUSE A2AET8_MOUSE QEAVTQVEFLLSQQRELGDITGNLAQVKQRLKKLEILDDKSQELLTKARIVILRGHKLAS B7Z3Y5_HUMAN B7Z3Y5_HUMAN QQLVTEVEFLLNQQAELADVTGTIAQVKQKIKKLENLDENSQELLSKAQFVILHGHKLAA Q5JYJ2_HUMAN Q5JYJ2_HUMAN QQLVTEVEFLLNQQAELADVTGTIAQVKQKIKKLENLDENSQELLSKAQFVILHGHKLAA B7Z3Z2_HUMAN B7Z3Z2_HUMAN QQLVTEVEFLLNQQAELADVTGTIAQVKQKIKKLENLDENSQELLSKAQFVILHGHKLAA B2R9S6_HUMAN B2R9S6_HUMAN QQLVTEVEFLLNQQAELADVTGTIAQVKQKIKKLENLDENSQELLSKAQFVILHGHKLAA B7Z869_HUMAN B7Z869_HUMAN QQLVTEVEFLLNQQAELADVTGTIAQVKQKIKKLENLDENSQELLSKAQFVILHGHKLAA B7ZAV1_HUMAN B7ZAV1_HUMAN QQLVTEVEFLLNQQAELADVTGTIAQVKQKIKKLENLDENSQELLSKAQFVILHGHKLAA Q5JYJ7_HUMAN Q5JYJ7_HUMAN QQLVTEVEFLLNQQAELADVTGTIAQVKQKIKKLENLDENSQELLSKAQFVILHGHKLAA Q5JYJ5_HUMAN Q5JYJ5_HUMAN ------------------------------------------------------------ Q5JYJ6_HUMAN Q5JYJ6_HUMAN ------------------------------------------------------------ Q5JYJ3_HUMAN Q5JYJ3_HUMAN QQLVTEVEFLLNQQAELADVTGTIAQVKQKIKKLENLDENSQELLSKAQFVILHGHKLAA MCF2_HUMAN MCF2_HUMAN QQLVTEVEFLLNQQAELADVTGTIAQVKQKIKKLENLDENSQELLSKAQFVILHGHKLAA Q4S0P7_TETNG Q4S0P7_TETNG SEVRTQLEQVSEKLLTFSEVGISPAHADHIFAEHTAYEERVNELLDRAASLAQEGEDLVQ B8A4Q6_DANRE B8A4Q6_DANRE ------------------------------------------------------------ MCF2L_RAT MCF2L_RAT REVKTALDSMSQKIAAFTDVGNSLAHVQHLLKDLTTFEEKSSVAVT-SQSPVLEGQQLIE Q3UHQ9_MOUSE Q3UHQ9_MOUSE REVKTTLDSMSQKIAAFTDVGNSLAHVQHLLKDLTAFEEKSSVAVDKARALSLEGQQLIE Q6PDM6_MOUSE Q6PDM6_MOUSE REVKTTLDSMSQKIAAFTDVGNSLAHVQHLLKDLTAFEEKSSVAVDKARALSLEGQQLIE Q8C7Z1_MOUSE Q8C7Z1_MOUSE REVKTTLDSMSQKIAAFTDVGNSLAHVQHLLKDLTAFEEKSSVAVDKARALSLEGQQLIE Q80U26_MOUSE Q80U26_MOUSE --------SMSQKIAAFTDVGNSLAHVQHLLKDLTAFEEKSSVAVDKARALSLEGQQLIE MCF2L_MOUSE MCF2L_MOUSE REVKTTLDSMSQKIAAFTDVGNSLAHVQHLLKDLTAFEEKSSVAVDKARALSLEGQQLIE Q003U3_MOUSE Q003U3_MOUSE REVKTTLDSMSQKIAAFTDVGNSLAHVQHLLKDLTAFEEKSSVAVDKARALSLEGQQLIE B5SNI0_OTOGA B5SNI0_OTOGA REVKAALDVVSQKIATFTDVGNSLAHVEHLLKDLSSFEEKSSVAMGRARALCLDGEQLIE B3KT13_HUMAN B3KT13_HUMAN REVKAILDAASQKIATFTDIGNSLAHVEHLLRDLASFEEKSGVAVERARALSLDGEQLIG A9X169_PAPAN A9X169_PAPAN REVKAVLDTVCQKIATFTDIGNSLAHVEHLLRDLASFEEKSGVSVERARALSLDGEQLIE B1MTD7_CALMO B1MTD7_CALMO REVKAVLDAVSQKMATFSDVGNSLAHVEHLLRDLASFEEKSSVAVERARALSLDGEQLIE Q5REI0_PONAB Q5REI0_PONAB REVKAILDAVSRKIATFTDIGNSLAHVEHLLRDLAGFEEKSGVAMERARALSLDGEQLIE B4DHD6_HUMAN B4DHD6_HUMAN REVKAILDAASQKIATFTDIGNSLAHVEHLLRDLASFEEKSGVAVERARALSLDGEQLIG B4DIL6_HUMAN B4DIL6_HUMAN REVKAILDAASQKIATFTDIGNSLAHVEHLLRDLASFEEKSGVAVERARALSLDGEQLIG B7Z9K4_HUMAN B7Z9K4_HUMAN REVKAILDAASQKIATFTDIGNSLAHVEHLLRDLASFEEKSGVAVERARALSLDGEQLIG MCF2L_HUMAN MCF2L_HUMAN REVKAILDAASQKIATFTDIGNSLAHVEHLLRDLASFEEKSGVAVERARALSLDGEQLIG A8MU87_HUMAN A8MU87_HUMAN ---------XSQKIATFTDIGNSLAHVEHLLRDLASFEEKSGVAVERARALSLDGEQLIG B7ZBJ8_HUMAN B7ZBJ8_HUMAN ----------SQKIATFTDIGNSLAHVEHLLRDLASFEEKSGVAVERARALSLDGEQLIG B8A4Q9_DANRE B8A4Q9_DANRE REVRAHLDLVYDRLSGFSEVGISPAHAEHILKELTNHEERASEVMDQALSLASDADQLIE Q4RY59_TETNG Q4RY59_TETNG REVRAQLDATSERLSGFSEVSVSPAHADHVLRELSGHEGKACDVLDRALSLAGEGDRLIE Q4SVF8_TETNG Q4SVF8_TETNG QQMEEVLRRLGEQEKAVAPVGTTVVQAEQLLRDLELLDTQAQEEMARAQMVILHGHQLAA Q4RP67_TETNG Q4RP67_TETNG QEMETRLQDLISEERELLVSASSLAQTEQVLKRFDSLESNAQEVMSQTQIIVLHGHQLSA Q7ZZ90_DANRE Q7ZZ90_DANRE QEMECSLEKLRAQERKISIIGESLNQTEQSVRELDGLDKRAQEEMSRAQVLILHGHQLAA MATCH CONSENSUS ????????????????????????A????????L?????????????A????L?G??L??

MF2L2_HUMAN MF2L2_HUMAN SHHYAADAIRPRCVELRHLCDDFINGNKKKWDILGKSLEFHRQLDKVSQWCEAGIYLLAS A2AEU1_MOUSE A2AEU1_MOUSE NHHYALDLICQRCNELRYLSDILVNEIRTKRVQLSRTFKVHRLLQQARQCCDQGECLLAS Q8BLE2_MOUSE Q8BLE2_MOUSE NHHYALDLICQRCNELRYLSDILVNEIRTKRVQLSRTFKVHRLLQQARQCCDQGECLLAS Q99N72_MOUSE Q99N72_MOUSE NHHYALDLICQRCNELRYLSDILVNEIRTKRVQLSRTFKVHRLLQQARQCCDQGECLLAS Q7TNJ5_MOUSE Q7TNJ5_MOUSE NHHYALDLICQRCNELRYLSDILVNEIRTKRVQLSRTFKVHRLLQQARQCCDQGECLLAS Q8C067_MOUSE Q8C067_MOUSE NHHYALDLICQRCNELRYLSDILVNEIRTKRVQLSRTFKVHRLLQQARQCCDQGECLLAS A2AET8_MOUSE A2AET8_MOUSE NHHYALDLICQRCNELRYLSDILVNEIRTKRVQLSRTFKVHRLLQQARQCCDQGECLLAS B7Z3Y5_HUMAN B7Z3Y5_HUMAN NHHYALDLICQRCNELRYLSDILVNEIKAKRIQLSRTFKMHKLLQQARQCCDEGECLLAN Q5JYJ2_HUMAN Q5JYJ2_HUMAN NHHYALDLICQRCNELRYLSDILVNEIKAKRIQLSRTFKMHKLLQQARQCCDEGECLLAN B7Z3Z2_HUMAN B7Z3Z2_HUMAN NHHYALDLICQRCNELRYLSDILVNEIKAKRIQLSRTFKMHKLLQQARQCCDEGECLLAN B2R9S6_HUMAN B2R9S6_HUMAN NHHYALDLICQRCNELRYLSDILVNEIKAKRIQLSRTFKMHKLLQQARQCCDEGECLLAN B7Z869_HUMAN B7Z869_HUMAN NHHYALDLICQRCNELRYLSDILVNEIKAKRIQLSRTFKMHKLLQQARQCCDEGECLLAN B7ZAV1_HUMAN B7ZAV1_HUMAN NHHYALDLICQRCNELRYLSDILVNEIKAKRIQLSRTFKMHKFLQQARQCCDEGECLLAN Q5JYJ7_HUMAN Q5JYJ7_HUMAN NHHYALDLICQRCNELRYLSDILVNEIKAKRIQLSRTFKMHKLLQQARQCCDEGECLLAN Q5JYJ5_HUMAN Q5JYJ5_HUMAN ------------------------------------------------------------ Q5JYJ6_HUMAN Q5JYJ6_HUMAN ------------------------------------------------------------ Q5JYJ3_HUMAN Q5JYJ3_HUMAN NHHYALDLICQRCNELRYLSDILVNEIKAKRIQLSRTFKMHKLLQQARQCCDEGECLLAN MCF2_HUMAN MCF2_HUMAN NHHYALDLICQRCNELRYLSDILVNEIKAKRIQLSRTFKMHKLLQQARQCCDEGECLLAN Q4S0P7_TETNG Q4S0P7_TETNG KSHYAQDSIQLKCTEISTISEDVRAGLKARREQLLKAMKLHHALERASKWVDDGIYLLAS B8A4Q6_DANRE B8A4Q6_DANRE ------------------------------------------------------------ MCF2L_RAT MCF2L_RAT NRHYAVDSIHPKCEELQHLCDHFASEVTRRRDLLSKSLELHSLLETSMKWSDEGIFLLAS Q3UHQ9_MOUSE Q3UHQ9_MOUSE NRHYAVDSIHPKCEELQHLCDHFASEVTRRRGLLSKSLELHSLLETSMKWSDEGIFLLAS Q6PDM6_MOUSE Q6PDM6_MOUSE NRHYAVDSIHPKCEELQHLCDHFASEVTRRRGLLSKSLELHSLLETSMKWSDEGIFLLAS Q8C7Z1_MOUSE Q8C7Z1_MOUSE NRHYAVDSIHPKCEELQHLCDHFASEVTRRRGLLSKSLELHSLLETSMKWSDEGIFLLAS Q80U26_MOUSE Q80U26_MOUSE NRHYAVDSIHPKCEELQHLCDHFASEVTRRRGLLSKSLELHSLLETSMKWSDEGIFLLAS MCF2L_MOUSE MCF2L_MOUSE NRHYAVDSIHPKCEELQHLCDHFASEVTRRRGLLSKSLELHSLLETSMKWSDEGIFLLAS Q003U3_MOUSE Q003U3_MOUSE NRHYAVDSIHPKCEELQHLCDHFASEVTRRRGLLSKSLELHSLLETSMKWSDEGIFLLAS B5SNI0_OTOGA B5SNI0_OTOGA NKHYAIDSIRPKCEELRHLCDQFTAEVGRRRGLLTKALGLHSLLETSMKWCDQGIYLLAS B3KT13_HUMAN B3KT13_HUMAN NKHYAVDSIRPKCQELRHLCDQFSAEIARRRGLLSKSLELHRRLETSMKWCDERIYLLAS A9X169_PAPAN A9X169_PAPAN NKHYAVDSIRPKCQELRHLCDQFSAEIVRRRGLLGKSLELHRRLETSLKWCDEGIYLLAS B1MTD7_CALMO B1MTD7_CALMO NKHYAVDSIRPKCQELRHLCDQFSAEIAGRRGLLSKSLELHRRLETSMKWCDEGIYLLAS Q5REI0_PONAB Q5REI0_PONAB NKHYAVDSIRPKCQELRHLCDQFSAEITRRRGLLNKSLELHRRLETSMKWCDEGIYLLAS B4DHD6_HUMAN B4DHD6_HUMAN NKHYAVDSIRPKCQELRHLCDQFSAEIARRRGLLSKSLELHRRLETSMKWCDEGIYLLAS B4DIL6_HUMAN B4DIL6_HUMAN NKHYAVDSIRPKCQELRHLCDQFSAEIARRRGLLSKSLELHRRLETSMKWCDEGIYLLAS B7Z9K4_HUMAN B7Z9K4_HUMAN NKHYAVDSIRPKCQELRHLCDQFSAEIARRRGLLSKSLELHRRLETSMKWCDEGIYLLAS MCF2L_HUMAN MCF2L_HUMAN NKHYAVDSIRPKCQELRHLCDQFSAEIARRRGLLSKSLELHRRLETSMKWCDEGIYLLAS A8MU87_HUMAN A8MU87_HUMAN NKHYAVDSIRPKCQELRHLCDQFSAEIARRRGLLSKSLELHRRLETSMKWCDEGIYLLAS B7ZBJ8_HUMAN B7ZBJ8_HUMAN NKHYAVDSIRPKCQELRHLCDQFSAEIARRRGLLSKSLELHRRLETSMKWCDEGIYLLAS B8A4Q9_DANRE B8A4Q9_DANRE ASHYAVDSILPKCSELRSVCEEISTILRAKKAYLFKSVELHQCLEKATKWYDDGIYLLAS Q4RY59_TETNG Q4RY59_TETNG NSHYAEDSIRPKCSELRSVCEEINSTLRSKKSLLLRAMELHHALEKALRWCEEGIFLLAS Q4SVF8_TETNG Q4SVF8_TETNG NHHYALALIVQRCNELRHLCDVVTA--------------------AALRWCDEGAYLLAS Q4RP67_TETNG Q4RP67_TETNG GHHYAVALIMQRCNELRHYCDTLDAALKAKRAHLLQTHQLLLCLGQAQTWCDDGAYLLAN Q7ZZ90_DANRE Q7ZZ90_DANRE GHHYAMALIIQRCNELRHQCDTLTSALSTKRSSLTQAQTLLHRLEEAQRWCDDGAYLLAN MATCH CONSENSUS N?HYA?D?I???C?EL??L?D?????????R??L??????H??L???????D?G??LLA?

MF2L2_HUMAN MF2L2_HUMAN QAVDKCQSREGVDIALNDIATFLGTVKEYPLLSPKEFYNEFELLLTLD------------ A2AEU1_MOUSE A2AEU1_MOUSE QGMDKFQTKEDAQKALQDVDNFLQMAMPFINYDIESLQYEFDVLLSPE------------ Q8BLE2_MOUSE Q8BLE2_MOUSE QGMDKFQTKEDAQKALQDVDNFLQMAMPFINYDIESLQYEFDVLLSPE------------ Q99N72_MOUSE Q99N72_MOUSE QGMDKFQTKEDAQKALQDVDNFLQMAMPFINYDIESLQYEFDVLLSPE------------ Q7TNJ5_MOUSE Q7TNJ5_MOUSE QGMDKFQTKEDAQKALQDVDNFLQMAMPFINYDIESLQYEFDVLLSPE------------ Q8C067_MOUSE Q8C067_MOUSE QGMDKFQTKEDAQKALQDVDNFLQMAMPFINYDIESLQYEFDVLLSPE------------ A2AET8_MOUSE A2AET8_MOUSE QGMDKFQTKEDAQKALQDVDNFLQMAMPFINYDIESLQYEFDVLLSPE------------ B7Z3Y5_HUMAN B7Z3Y5_HUMAN QEIDKFQSKEYAQKALQDIENFLEMALPFINYEPETLQYEFDVILSPE------------ Q5JYJ2_HUMAN Q5JYJ2_HUMAN QEIDKFQSKEDAQKALQDIENFLEMALPFINYEPETLQYEFDVILSPE------------ B7Z3Z2_HUMAN B7Z3Z2_HUMAN QEIDKFQSKEDAQKALQDIENFLEMVLPFINYEPETLQYEFDVILSPE------------ B2R9S6_HUMAN B2R9S6_HUMAN QEIDKFQSKEDAQKALQDIENFLEMALPFINYEPETLQYEFDVILSPE------------ B7Z869_HUMAN B7Z869_HUMAN QEIDKFQSKEDAQKALQDIENFLEMALPFINYEPETLQYEFDVILSPE------------ B7ZAV1_HUMAN B7ZAV1_HUMAN QEIDKFQSKEDAQKALQDIENFLEMALPFINYEPETLQYEFDVILSPE------------ Q5JYJ7_HUMAN Q5JYJ7_HUMAN QEIDKFQSKEDAQKALQDIENFLEMALPFINYEPETLQYEFDVILSPE------------ Q5JYJ5_HUMAN Q5JYJ5_HUMAN ------------------------------------------------------------ Q5JYJ6_HUMAN Q5JYJ6_HUMAN ------------------------------------------------------------ Q5JYJ3_HUMAN Q5JYJ3_HUMAN QEIDKFQSKEDAQKALQDIENFLEMALPFINYEPETLQYEFDVILSPE------------ MCF2_HUMAN MCF2_HUMAN QEIDKFQSKEDAQKALQDIENFLEMALPFINYEPETLQYEFDVILSPE------------ Q4S0P7_TETNG Q4S0P7_TETNG QPVDKCLSHEGAELALQELEGYLNNAQQNQLSDPSTIWTEYEAVLNPQ------------ B8A4Q6_DANRE B8A4Q6_DANRE ------------------------------------------------------------ MCF2L_RAT MCF2L_RAT QPVDKCQSQDGAEAALQEIEKFLETGAENKIQELNKIYKEYECILNQD------------ Q3UHQ9_MOUSE Q3UHQ9_MOUSE QPVDKCQSQDGAEAALQEIEKFLETGAENKIQELNEIYKEYECILNQD------------ Q6PDM6_MOUSE Q6PDM6_MOUSE QPVDKCQSQDGAEAALQEIEKFLETGAENKIQELNEIYKEYECILNQD------------ Q8C7Z1_MOUSE Q8C7Z1_MOUSE QPVDKCQSQDGAEAALQEIEKFLETGA--------------------------------- Q80U26_MOUSE Q80U26_MOUSE QPVDKCQSQDGAEAALQEIEKFLETGAENKIQELNEIYKEYECILNQD------------ MCF2L_MOUSE MCF2L_MOUSE QPVDKCQSQDGAEASFQEIEKFLETGAENKIQELNEIYKEYECILNQD------------ Q003U3_MOUSE Q003U3_MOUSE QPVDKCQSQDGAEASFQEIEKFLETGAENKIQELNEIYKEYECILNQD------------ B5SNI0_OTOGA B5SNI0_OTOGA QPVDKCQSQDGAEAALQEIEKFLETGAENKIQELSNIYKEYESILNQD------------ B3KT13_HUMAN B3KT13_HUMAN QPVDKCQSQDGAEAALQEIEKFLETGAENKIQELNAIYKEYESILNQD------------ A9X169_PAPAN A9X169_PAPAN QPVDKCQSQDGAEAALQEIEKFLETSAENKIQELNTIYKEYESILNQD------------ B1MTD7_CALMO B1MTD7_CALMO QPVDKCQSQDGAEAALQEIEKFLETGTENKIQELSVIYKEYESILNQD------------ Q5REI0_PONAB Q5REI0_PONAB QPVDKCQSQDGAEAALQEIEKFLETGAENKIQELNTIYKEYESILNQD------------ B4DHD6_HUMAN B4DHD6_HUMAN QPVDKCQSQDGAEAALQEIEKFLETGAENKIQELNAIYKEYESILNQD------------ B4DIL6_HUMAN B4DIL6_HUMAN QPVDKCQSQDGAEAALQEIEKFLETGAENKIQELNAIYKEYESILNQD------------ B7Z9K4_HUMAN B7Z9K4_HUMAN QPVDKCQSQDGAEAALQEIEKFLETGAENKIQELNAIYKEYESILNQD------------ MCF2L_HUMAN MCF2L_HUMAN QPVDKCQSQDGAEAALQEIEKFLETGAENKIQELNAIYKEYESILNQD------------ A8MU87_HUMAN A8MU87_HUMAN QPVDKCQSQDGAEAALQEIEKFLETGAENKIQELNAIYKEYESILNQD------------ B7ZBJ8_HUMAN B7ZBJ8_HUMAN QPVDKCQSQDGAEAALQEIEKFLETGAENKIQELNAIYKEYESILNQD------------ B8A4Q9_DANRE B8A4Q9_DANRE QPVDKCQSQDGAESALQEIERYLDTANQHKLTDLNGIWRDYDSVLTQD------------ Q4RY59_TETNG Q4RY59_TETNG QPVDRCQSQDGAEAALQELERYLDTAPLHTLADRSTVCCQYEAILTAQ------------ Q4SVF8_TETNG Q4SVF8_TETNG QMVDRFQTKEGAQEALQSLSTHQERAPSALRNSQGILSLEFEAILTPQLQVLLSPRRRRL Q4RP67_TETNG Q4RP67_TETNG QLVDKLQSKEGAQAALQDIEKFLEEAPSMLSSGPDVLAAEYEGVITPE------------ Q7ZZ90_DANRE Q7ZZ90_DANRE QQVEKCQCKEGAQTALRDIEKFQEAAPPLLTAGADVLFLEYESVLTPY------------ MATCH CONSENSUS Q??DK?Q????A??ALQ????FL????????????????E????L???????????????

MF2L2_HUMAN MF2L2_HUMAN --------------AKAKAQKVLQRLDDVQEIFHKRQVSLMKLAAKQTRPVQPVAPHPES A2AEU1_MOUSE A2AEU1_MOUSE --------------LKAQMQNIQLKLENIRSAFQNQQAGCKSLKEVPEGAFQNLVPASE- Q8BLE2_MOUSE Q8BLE2_MOUSE --------------LKAQMQNIQLKLENIRSAFQNQQAGCKSLKEVPEGAFQNLVPASE- Q99N72_MOUSE Q99N72_MOUSE --------------LKAQMQNIQLKLENIRSAFQNQQAGCKSLKEVPEGAFQNLVPASE- Q7TNJ5_MOUSE Q7TNJ5_MOUSE --------------LKAQMQNIQLKLENIRSAFQNQQAGCKSLKEVPEGAFQNLVPASE- Q8C067_MOUSE Q8C067_MOUSE --------------LKAQMQNIQLKLENIRSAFQNQQAGCKSLKEVPEGAFQNLVPASE- A2AET8_MOUSE A2AET8_MOUSE --------------LKAQMQNIQLKLENIRSAFQNQQAGCKSLKEVPEGAFQNLVPASE- B7Z3Y5_HUMAN B7Z3Y5_HUMAN --------------LKVQMKTIQLKLENIRSIFENQQAGFRNLADKHVRPIQFVVPTPE- Q5JYJ2_HUMAN Q5JYJ2_HUMAN --------------LKVQMKTIQLKLENIRSIFENQQAGFRNLADKHVRPIQFVVPTPE- B7Z3Z2_HUMAN B7Z3Z2_HUMAN --------------LKVQMKTIQLKLENIRSIFENQQAGFRNLADKHVRPIQFVVPTPE- B2R9S6_HUMAN B2R9S6_HUMAN --------------LKVQMKTIQLKLENIRSIFENQQAGFRNLADKHVRPIQFVVPTPE- B7Z869_HUMAN B7Z869_HUMAN --------------LKVQMKTIQLKLENIRSIFENQQAGFRNLADKHVRPIQFVVPTPE- B7ZAV1_HUMAN B7ZAV1_HUMAN --------------LKVQMKTIQLKLENIRSIFENQQAGFRNLADKHVRPIQFVVPTPE- Q5JYJ7_HUMAN Q5JYJ7_HUMAN --------------LKVQMKTIQLKLENIRSIFENQQAGFRNLADKHVRPIQFVVPTPE- Q5JYJ5_HUMAN Q5JYJ5_HUMAN ----------------VQMKTIQLKLENIRSIFENQQAGFRNLADKHVRPIQFVVPTPE- Q5JYJ6_HUMAN Q5JYJ6_HUMAN ------------------------------------------------------------ Q5JYJ3_HUMAN Q5JYJ3_HUMAN --------------LKVQMKTIQLKLENIRSIFENQQAGFRNLADKHVRPIQFVVPTPE- MCF2_HUMAN MCF2_HUMAN --------------LKVQMKTIQLKLENIRSIFENQQAGFRNLADKHVRPIQFVVPTPE- Q4S0P7_TETNG Q4S0P7_TETNG --------------FKDQVEKVFQKQLSMQDMFDKRRVSLKKLATKQTRPVQPVAPRPE- B8A4Q6_DANRE B8A4Q6_DANRE ------------------------------------------------------------ MCF2L_RAT MCF2L_RAT --------------LLEHVQKVFQKQESTEEMFHRRQASLKKLAAKQTRPVQPVAPRPE- Q3UHQ9_MOUSE Q3UHQ9_MOUSE --------------LLEHVQKVFQKQESTEEMFHRRQASLKKLAAKQTRPVQPVAPRPE- Q6PDM6_MOUSE Q6PDM6_MOUSE --------------LLEHVQKVFQKQESTEEMFHRRQASLKKLAAKQTRPVQPVAPRPE- Q8C7Z1_MOUSE Q8C7Z1_MOUSE ------------------------------------------------------------ Q80U26_MOUSE Q80U26_MOUSE --------------LLEHVQKVFQKQESTEEMFHRRQASLKKLAAKQTRPVQPVAPRPE- MCF2L_MOUSE MCF2L_MOUSE --------------LLEHVQKVFQKQESTEEMFHRRQASLKKLAAKQTRPVQPVAPRPE- Q003U3_MOUSE Q003U3_MOUSE --------------LLEHVQKVFQKQESTEEMFHRRQASLKKLAAKQTRPVQPVAPRPE- B5SNI0_OTOGA B5SNI0_OTOGA --------------LMEHVRKVFQKQESMEEMFHRRQASLKKLAAKQTRPVQPVAPRPE- B3KT13_HUMAN B3KT13_HUMAN --------------LMEHVRKVFQKQASMEEVFHRRQASLKKLAARQTRPVQPVAPRPE- A9X169_PAPAN A9X169_PAPAN --------------LMEHVRKVFQKQASMEEVFHRRQASLKKLAARQTRPVQPVAPRPE- B1MTD7_CALMO B1MTD7_CALMO --------------LMEHVRKVFQKQASMEEVFHRRQASLKKLAARQTRPVQPVAPRPE- Q5REI0_PONAB Q5REI0_PONAB --------------LMEHVRKVFQKQASMEEVFHRRQASLKKLAARQTRPVQPVAPRPE- B4DHD6_HUMAN B4DHD6_HUMAN --------------LMEHVRKVFQKQASMEEVFHRRQASLKKLAARQTRPVQPVAPRPE- B4DIL6_HUMAN B4DIL6_HUMAN --------------LMEHVRKVFQKQASMEEVFHRRQASLKKLAARQTRPVQPVAPRPE- B7Z9K4_HUMAN B7Z9K4_HUMAN --------------LMEHVRKVFQKQASMEEVFHRRQASLKKLAARQTRPVQPVAPRPE- MCF2L_HUMAN MCF2L_HUMAN --------------LMEHVRKVFQKQASMEEVFHRRQASLKKLAARQTRPVQPVAPRPE- A8MU87_HUMAN A8MU87_HUMAN --------------LMEHVRKVFQKQASMEEVFHRRQASLKKLAARQTRPVQPVAPRPE- B7ZBJ8_HUMAN B7ZBJ8_HUMAN --------------LMEHVRKVFQKQASMEEVFHRRQASLKKLAARQTRPVQPVAPRPE- B8A4Q9_DANRE B8A4Q9_DANRE --------------FRDQVDKVFQKQLSMQEMFEKRRVSLKKLAAKQTRPVQPVAPRPE- Q4RY59_TETNG Q4RY59_TETNG --------------LMDQIERVFQKQSSVQEMFEKRRVSLKKLAAKQTRPVQPVAPRPE- Q4SVF8_TETNG Q4SVF8_TETNG KQPLVLGLLLFLLPLQSQISAVSEKLNMVQSMIRNRELCLRKLADVQVRPVQLVAPRPEL Q4RP67_TETNG Q4RP67_TETNG --------------LQTQIGETFEKHVAVQQMIQNRQACLRKLADKQVRPVQLVAPRPE- Q7ZZ90_DANRE Q7ZZ90_DANRE --------------LQSHIEKTFQKYSSVQALIQSRQICLKKMADKHIRPIQLVAPRPE- MATCH CONSENSUS ??????????????L?????????K???????F???Q?????L????????Q???P??E?

MF2L2_HUMAN MF2L2_HUMAN SPKWVSSKTSQ-------------------------PSTSV-PLARPLRTSEEPYTETEL A2AEU1_MOUSE A2AEU1_MOUSE --NVMRSRMIF-------------------------FSPKH----------------VKK Q8BLE2_MOUSE Q8BLE2_MOUSE --NVMRSRMIF-------------------------FSPKH----------------VKK Q99N72_MOUSE Q99N72_MOUSE --NVMRSRMIF-------------------------FSPKH----------------VKK Q7TNJ5_MOUSE Q7TNJ5_MOUSE --NVMRSRMIF-------------------------FSPKHVGIGYSFFQACRIFLKVKK Q8C067_MOUSE Q8C067_MOUSE --NVMRSRMIF-------------------------FSPKH----------------VKK A2AET8_MOUSE A2AET8_MOUSE --NVMRSRMIF-------------------------FSPKHVGIGYSFFQACRIFLKVKK B7Z3Y5_HUMAN B7Z3Y5_HUMAN --NLVTSGTPF-------------------------FSSKQ----------------GKK Q5JYJ2_HUMAN Q5JYJ2_HUMAN --NLVTSGTPF-------------------------FSSKQ----------------GKK B7Z3Z2_HUMAN B7Z3Z2_HUMAN --NLVTSGTPF-------------------------FSSKQ----------------GKK B2R9S6_HUMAN B2R9S6_HUMAN --NLVTSGTPF-------------------------FSSKQ----------------GKK B7Z869_HUMAN B7Z869_HUMAN --NLVTSGTPF-------------------------FSSKQVGVGYSFFQACKLFSKGKK B7ZAV1_HUMAN B7ZAV1_HUMAN --NLVTSGTPF-------------------------FSSKQVGVGYSFFQACKLFSKGKK Q5JYJ7_HUMAN Q5JYJ7_HUMAN --NLVTSGTPF-------------------------FSSKQ----------------GKK Q5JYJ5_HUMAN Q5JYJ5_HUMAN --NLVTSGTPF-------------------------FSSKQ----------------GKK Q5JYJ6_HUMAN Q5JYJ6_HUMAN ------------------------------------------------------------ Q5JYJ3_HUMAN Q5JYJ3_HUMAN --NLVTSGTPF-------------------------FSSKQVGVGYSFFQACKLFSKGKK MCF2_HUMAN MCF2_HUMAN --NLVTSGTPF-------------------------FSSKQ----------------GKK Q4S0P7_TETNG Q4S0P7_TETNG --AFIKSPLSS-------------------------PG---QPSHSS----------TNT B8A4Q6_DANRE B8A4Q6_DANRE ------------------------------------------------------------ MCF2L_RAT MCF2L_RAT --ALTKSPSPS-------------------------PGSWRSSENSS----------SEG Q3UHQ9_MOUSE Q3UHQ9_MOUSE --ALTKSPSPS-------------------------PGSWRSSENSS----------SEG Q6PDM6_MOUSE Q6PDM6_MOUSE --ALTKSPSPS-------------------------PGSWRSSENSS----------SEG Q8C7Z1_MOUSE Q8C7Z1_MOUSE ------------------------------------------------------------ Q80U26_MOUSE Q80U26_MOUSE --ALTKSPSPS-------------------------PGSWRSSENSS----------SEG MCF2L_MOUSE MCF2L_MOUSE --ALTKSPSPS-------------------------PGSWRSSENSS----------SEG Q003U3_MOUSE Q003U3_MOUSE --ALTKSPSPS-------------------------PGSWRSSENSS----------SEG B5SNI0_OTOGA B5SNI0_OTOGA --ALTKSPCPS-------------------------PGMRRGSENSS----------SEG B3KT13_HUMAN B3KT13_HUMAN --TLAKSPCPS-------------------------PGIRRGSENSS----------SEG A9X169_PAPAN A9X169_PAPAN --ALAKSPCPS-------------------------PGIRRGSENSS----------SEG B1MTD7_CALMO B1MTD7_CALMO --ALAKSPCPS-------------------------PGIRRGSENSS----------SEG Q5REI0_PONAB Q5REI0_PONAB --ALAKSPCPS-------------------------PGIRRGSENSS----------SEG B4DHD6_HUMAN B4DHD6_HUMAN --ALAKSPSPS-------------------------PGIRRGSENSS----------SEG B4DIL6_HUMAN B4DIL6_HUMAN --ALAKSPCPS-------------------------PGIRRGSENSS----------SEG B7Z9K4_HUMAN B7Z9K4_HUMAN --ALAKSPCPS-------------------------PGIRRGSENSS----------SEG MCF2L_HUMAN MCF2L_HUMAN --ALAKSPCPS-------------------------PGIRRGSENSS----------SEG A8MU87_HUMAN A8MU87_HUMAN --ALAKSPCPS-------------------------PGIRRGSENSS----------SEG B7ZBJ8_HUMAN B7ZBJ8_HUMAN --ALAKSPCPS-------------------------PGIRRGSENSS----------SEG B8A4Q9_DANRE B8A4Q9_DANRE --AIIKTPVSS-------------------------P----------------------- Q4RY59_TETNG Q4RY59_TETNG ----GDSPIPN-------------------------GGTRHASL---------------- Q4SVF8_TETNG Q4SVF8_TETNG DQTSQRCKSPL-------------------------FSPKH---DFNILNSKFSFDLLPG Q4RP67_TETNG Q4RP67_TETNG --NPPRSKSPFSPKHGDGLKFTFDLPLPGKRVSRKSPNPRKVRTETILVNIRVTFS-CQR Q7ZZ90_DANRE Q7ZZ90_DANRE --NPPRSKSPL-------------------------FSPKH------------------- MATCH CONSENSUS ??????S?????????????????????????????????????????????????????

MF2L2_HUMAN MF2L2_HUMAN NSRGKEDDETK----------FEVKSEEIFESHHER--------GNPELEQQARLGDLSP A2AEU1_MOUSE A2AEU1_MOUSE SWR-QIHAQSN----------VKV---EAVEDSQEK-NSD----QSPKLD--NSLDIL-- Q8BLE2_MOUSE Q8BLE2_MOUSE SWR-QIHAQSN----------VKV---EAVEDSQEK-NSD----QSPKLD--NSLDIL-- Q99N72_MOUSE Q99N72_MOUSE SWR-QIRAQSN----------VKV---EAVEDSQEK-NSD----QSPKLD--NSLDIL-- Q7TNJ5_MOUSE Q7TNJ5_MOUSE SWR-QIRAQSN----------VKV---EAVEDSQEK-NSD----QSPKLD--NSLDIL-- Q8C067_MOUSE Q8C067_MOUSE SWR-QIHAQSN----------VKV---EAVEDSQEK-NSD----QSPKLD--NSLDIL-- A2AET8_MOUSE A2AET8_MOUSE SWR-QIHAQSN----------VKV---EAVEDSQEK-NSD----QSPKLD--NSLDIL-- B7Z3Y5_HUMAN B7Z3Y5_HUMAN TWR-Q--NQSN----------LKI---EVVPDCQEKRSSG----PSSSLDNGNSLDVL-- Q5JYJ2_HUMAN Q5JYJ2_HUMAN TWR-Q--NQSN----------LKI---EVVPDCQEKRSSG----PSSSLDNGNSLDVL-- B7Z3Z2_HUMAN B7Z3Z2_HUMAN TWR---QNQSN----------LKI---EVVPDCQEKRSSG----PSSSLDNGNSLDVL-- B2R9S6_HUMAN B2R9S6_HUMAN TWR-Q--NQSN----------LKI---EVVPDCQEKRSSG----PSSSLDNGNSLDVL-- B7Z869_HUMAN B7Z869_HUMAN TWR-Q--NQSN----------LKI---EVVPDCQEKRSSG----PSSSLDNGNSLDVL-- B7ZAV1_HUMAN B7ZAV1_HUMAN TWR-Q--NQSN----------LKI---EVVPDCQEKRSSG----PSSSLDNGNSLDVL-- Q5JYJ7_HUMAN Q5JYJ7_HUMAN TWR-Q--NQSN----------LKI---EVVPDCQEKRSSG----PSSSLDNGNSLDVL-- Q5JYJ5_HUMAN Q5JYJ5_HUMAN TWR-Q--NQSN----------LKI---EVVPDCQEKRSSG----PSSSLDNGNSLDVL-- Q5JYJ6_HUMAN Q5JYJ6_HUMAN ------------------------------------------------------------ Q5JYJ3_HUMAN Q5JYJ3_HUMAN TWR-Q--NQSN----------LKI---EVVPDCQEKRSSG----PSSSLDNGNSLDVL-- MCF2_HUMAN MCF2_HUMAN TWR---QNQSN----------LKI---EVVPDCQEKRSSG----PSSSLDNGNSLDVL-- Q4S0P7_TETNG Q4S0P7_TETNG GWA-RRTRQRR----------VLS---LAVTKEHNRHASL----SEEE----ENLAVL-- B8A4Q6_DANRE B8A4Q6_DANRE ------------------------------------------------------------ MCF2L_RAT MCF2L_RAT NAL-RRGPYRR----------AKS---EMSEPRQGRTSST----GEEE----ESLAIL-- Q3UHQ9_MOUSE Q3UHQ9_MOUSE NAL-RRGPYRR----------AKS---EMSEPRQGRTSST----GEEE----ESLAIL-- Q6PDM6_MOUSE Q6PDM6_MOUSE NAL-RRGPYRR----------AKS---EMSEPRQGRTSST----GEEE----ESLAIL-- Q8C7Z1_MOUSE Q8C7Z1_MOUSE ------------------------------------------------------------ Q80U26_MOUSE Q80U26_MOUSE NAL-RRGPYRR----------AKS---EMSEPRQGRTSST----GEEE----ESLAIL-- MCF2L_MOUSE MCF2L_MOUSE NAL-RRGPYRR----------AKS---EMSEPRQGRTSST----GEEE----ESLAIL-- Q003U3_MOUSE Q003U3_MOUSE NAL-RRGPYRR----------AKS---EMSEPRQGRTSST----GEEE----ESLAIL-- B5SNI0_OTOGA B5SNI0_OTOGA STL-RRGPYRR----------VKS---EMSGSRQGRSSSA----GDEE----ESLAVL-- B3KT13_HUMAN B3KT13_HUMAN GAL-RRGPYRR----------AKS---EMSESRQGR-GSA----GEEE----ESLAIL-- A9X169_PAPAN A9X169_PAPAN GAL-RRGPYRR----------AKS---EMSESRQGR-GSA----GEEE----ESLAIL-- B1MTD7_CALMO B1MTD7_CALMO SAL-RRGPYRR----------AKS---EMSESRQSR-GSA----GEE-----ESLAIL-- Q5REI0_PONAB Q5REI0_PONAB SAL-RRGPYRR----------AKS---EMSESRQGR-SSA----GEEE----ESLAIL-- B4DHD6_HUMAN B4DHD6_HUMAN GAL-RRGPYRR----------AKS---EMSESRQGR-GSA----GEEE----ESLAIL-- B4DIL6_HUMAN B4DIL6_HUMAN GAL-RRGPYRR----------AKS---EMSESRQGR-GSA----GEEE----ESLAIL-- B7Z9K4_HUMAN B7Z9K4_HUMAN GAL-RRGPYRR----------AKS---EMSESRQGR-GSA----GEEE----ESLAIL-- MCF2L_HUMAN MCF2L_HUMAN GAL-RRGPYRR----------AKS---EMSESRQGR-GSA----GEEE----ESLAIL-- A8MU87_HUMAN A8MU87_HUMAN GAL-RRGPYRR----------AKS---EMSESRQGR-GSA----GEEE----ESLAIL-- B7ZBJ8_HUMAN B7ZBJ8_HUMAN GAL-RRGPYRR----------AKS---EMSESRQGR-GSA----GEEE----ESLAIL-- B8A4Q9_DANRE B8A4Q9_DANRE ------------------------------------------------------------ Q4RY59_TETNG Q4RY59_TETNG --------------------------------------------SEEE----ENLAVL-- Q4SVF8_TETNG Q4SVF8_TETNG KRA-ARRNNCQ----------PKI---EVMHDFQGGRGCAYGPLPETDSETEDSPEQV-- Q4RP67_TETNG Q4RP67_TETNG VWQHDLFCNCKRNSRFRQFWCVQI---EVIHDYQESRSCV-----SYGLEGEDSPDLL-- Q7ZZ90_DANRE Q7ZZ90_DANRE ---------------------------EVIHDYQRSSS------LPYSIDGEDSSDLL-- MATCH CONSENSUS ???????????????????????????E?????Q???????????????????SL??L??

MF2L2_HUMAN MF2L2_HUMAN RRRIIRDLLETEEIYIKEIKSIID------------------------------GYITPM A2AEU1_MOUSE A2AEU1_MOUSE KNHVLNELIQTERAYVRELFTVLL------------------------------GYRSEM Q8BLE2_MOUSE Q8BLE2_MOUSE KNHVLNELIQTERAYVRELFTVLL------------------------------GYRSEM Q99N72_MOUSE Q99N72_MOUSE KNHVLDELIQTERAYVRELFTVLL------------------------------GYRSEM Q7TNJ5_MOUSE Q7TNJ5_MOUSE KNHVLDELIQTERAYVRELFTVLL------------------------------GYRSEM Q8C067_MOUSE Q8C067_MOUSE KNHVLNELIQTERAYVRELFTVLL------------------------------GYRSEM A2AET8_MOUSE A2AET8_MOUSE KNHVLNELIQTERAYVRELFTVLL------------------------------GYRSEM B7Z3Y5_HUMAN B7Z3Y5_HUMAN KNHVLNELIQTERVYVRELYTVLL------------------------------GYRAEM Q5JYJ2_HUMAN Q5JYJ2_HUMAN KNHVLNELIQTERVYVRELYTVLL------------------------------GYRAEM B7Z3Z2_HUMAN B7Z3Z2_HUMAN KNHVLNELIQTERVYVRELYTVLL------------------------------GYRAEM B2R9S6_HUMAN B2R9S6_HUMAN KNHVLNELIQTERVYVRELYTVLL------------------------------GYRAEM B7Z869_HUMAN B7Z869_HUMAN KNHVLNELIQTERVYVRELYTVLL------------------------------GYRAEM B7ZAV1_HUMAN B7ZAV1_HUMAN KNHVLNELIQTERVYVRELYTVLL------------------------------GYRAEM Q5JYJ7_HUMAN Q5JYJ7_HUMAN KNHVLNELIQTERVYVRELYTVLL------------------------------GYRAEM Q5JYJ5_HUMAN Q5JYJ5_HUMAN KNHVLNELIQTERVYVRELYTVLL------------------------------GYRAEM Q5JYJ6_HUMAN Q5JYJ6_HUMAN --HVLNELIQTERVYVRELYTVLL------------------------------GYRAEM Q5JYJ3_HUMAN Q5JYJ3_HUMAN KNHVLNELIQTERVYVRELYTVLL------------------------------GYRAEM MCF2_HUMAN MCF2_HUMAN KNHVLNELIQTERVYVRELYTVLL------------------------------GYRAEM Q4S0P7_TETNG Q4S0P7_TETNG RRHVMNELLETERAYVEELLCVLQ------------------------------GYASEM B8A4Q6_DANRE B8A4Q6_DANRE --HVMNELLETERAYVEELLCVLE------------------------------GYAAEM MCF2L_RAT MCF2L_RAT RRHVMNELLDTERAYVEELLCVLE------------------------------GYAAEM Q3UHQ9_MOUSE Q3UHQ9_MOUSE RRHVMNELLDTERAYVEELLCVLE------------------------------GYAAEM Q6PDM6_MOUSE Q6PDM6_MOUSE RRHVMNELLDTERAYVEELLCVLE------------------------------GYAAEM Q8C7Z1_MOUSE Q8C7Z1_MOUSE ------------------------------------------------------------ Q80U26_MOUSE Q80U26_MOUSE RRHVMNELLDTERAYVEELLCVLE------------------------------GYAAEM MCF2L_MOUSE MCF2L_MOUSE RRHVMNELLDTERAYVEELLCVLE------------------------------GYAAEM Q003U3_MOUSE Q003U3_MOUSE RRHVMNELLDTERAYVEELLCVLE------------------------------GYAAEM B5SNI0_OTOGA B5SNI0_OTOGA RRHVMNELLDTERAYVEELLCVLE------------------------------GYAAEM B3KT13_HUMAN B3KT13_HUMAN RRHVMSELLDTERAYVEELLCVLE------------------------------GYAAEM A9X169_PAPAN A9X169_PAPAN RRHVMSELLDTERAYVEELLCVLE------------------------------------ B1MTD7_CALMO B1MTD7_CALMO RRHVMSELLDTERAYVEELLCVLE------------------------------GYAAEM Q5REI0_PONAB Q5REI0_PONAB RRHVMSELLDTERAYVEELLCVLE------------------------------GYAAEM B4DHD6_HUMAN B4DHD6_HUMAN RRHVMSELLDTERAYVEELLCVLE------------------------------GYAAGM B4DIL6_HUMAN B4DIL6_HUMAN RRHVMSELLDTERAYVEELLCVLE------------------------------GYAAEM B7Z9K4_HUMAN B7Z9K4_HUMAN RRHVMSELLDTERAYVEELLCVLE------------------------------GYAAEM MCF2L_HUMAN MCF2L_HUMAN RRHVMSELLDTERAYVEELLCVLE------------------------------GYAAEM A8MU87_HUMAN A8MU87_HUMAN RRHVMSELLDTERAYVEELLCVLE------------------------------GYAAEM B7ZBJ8_HUMAN B7ZBJ8_HUMAN RRHVMSELLDTERAYVEELLCVLE------------------------------GYAAEM B8A4Q9_DANRE B8A4Q9_DANRE ------------------------------------------------------------ Q4RY59_TETNG Q4RY59_TETNG RRHVMNELLETERAYVEELLCVLE------------------------------GYAAEM Q4SVF8_TETNG Q4SVF8_TETNG TRHIMKELIATERIYVDELLSVLL------------------------------GYRAEM Q4RP67_TETNG Q4RP67_TETNG KRHVMKELFDTERIYVEELLSVLLVRAEIKQILLYIKQIYSYSVDINDSFPSLKGYRAEM Q7ZZ90_DANRE Q7ZZ90_DANRE KRHVMKELIETERIYVEELLAVLL------------------------------GYRAEM MATCH CONSENSUS ??HV??EL??TER?YV?EL??VL???????????????????????????????GY??EM

MF2L2_HUMAN MF2L2_HUMAN DFIWLKHLIPDVLQNNKDFLFGNIRELYEFHNRTFLKELEKCAENPELLAHCFLKR---- A2AEU1_MOUSE A2AEU1_MOUSE DNPQMFDLMPPLLRNKKDVLFGNMAEIYEFHNNIFMSRLEDCSDAPERVGPCFLER---- Q8BLE2_MOUSE Q8BLE2_MOUSE DNPQMFDLMPPLLRNKKDVLFGNMAEIYEFHNNIFMSRLEDCSDAPERVGPCFLER---- Q99N72_MOUSE Q99N72_MOUSE DNPQMFDLMPPLLRNKKDVLFGNMAEIYEFHNNIFMSRLEDCSDAPERVGPCFLER---- Q7TNJ5_MOUSE Q7TNJ5_MOUSE DNPQMFDLMPPLLRNKKDVLFGNMAEIYEFHNNIFMSRLEDCSDAPERVGPCFLER---- Q8C067_MOUSE Q8C067_MOUSE DNPQMFDLMPPLLRNKKDVLFGNMAEIYEFHNNIFMSRLEDCSDAPERVGPCFLER---- A2AET8_MOUSE A2AET8_MOUSE DNPQMFDLMPPLLRNKKDVLFGNMAEIYEFHNNIFMSRLEDCSDAPERVGPCFLER---- B7Z3Y5_HUMAN B7Z3Y5_HUMAN DNPEMFDLMPPLLRNKKDILFGNMAEIYEFHNDIFLSSLENCAHAPERVGPCFLER---- Q5JYJ2_HUMAN Q5JYJ2_HUMAN DNPEMFDLMPPLLRNKKDILFGNMAEIYEFHNDIFLSSLENCAHAPERVGPCFLER---- B7Z3Z2_HUMAN B7Z3Z2_HUMAN DNPEMFDLMPPLLRNKKDILFGNMAEIYGFHNDIFLSSLENCAHAPERVGPCFLER---- B2R9S6_HUMAN B2R9S6_HUMAN DNPEMFDLMPPLLRNKKDILFGNMAEIYEFHNDIFLSSLENCAHAPERVGPCFLER---- B7Z869_HUMAN B7Z869_HUMAN DNPEMFDLMPPLLRNKKDILFGNMAEIYEFHNDIFLSSLENCAHAPERVGPCFLER---- B7ZAV1_HUMAN B7ZAV1_HUMAN DNPEMFDLMPPLLRNKKDILFGNMAEIYEFHNDIFLSSLENCAHAPERVGPCFLER---- Q5JYJ7_HUMAN Q5JYJ7_HUMAN DNPEMFDLMPPLLRNKKDILFGNMAEIYEFHNDIFLSSLENCAHAPERVGPCFLER---- Q5JYJ5_HUMAN Q5JYJ5_HUMAN DNPEMFDLMPPLLRNKKDILFGNMAEIYEFHNDIFLSSLENCAHAPERVGPCFLER---- Q5JYJ6_HUMAN Q5JYJ6_HUMAN DNPEMFDLMPPLLRNKKDILFGNMAEIYEFHNDIFLSSLENCAHAPERVGPCFLER---- Q5JYJ3_HUMAN Q5JYJ3_HUMAN DNPEMFDLMPPLLRNKKDILFGNMAEIYEFHNDIFLSSLENCAHAPERVGPCFLER---- MCF2_HUMAN MCF2_HUMAN DNPEMFDLMPPLLRNKKDILFGNMAEIYEFHNDIFLSSLENCAHAPERVGPCFLER---- Q4S0P7_TETNG Q4S0P7_TETNG DNPAMLPLIPAPLQNKKEVLFGNMSEIYHFHKRTFLRELEQYTDCPELVGRCFLQR---- B8A4Q6_DANRE B8A4Q6_DANRE DNPAMSHLIPNTLLHKKDILFGNMSEIYQFHKKTFLRELEAYTDYPELVGQCFLER---- MCF2L_RAT MCF2L_RAT DNPLMAHLISTGLQNKKNILFGNMEEIYHFHNRIFLRELESCIDCPELVGRCFLER---- Q3UHQ9_MOUSE Q3UHQ9_MOUSE DNPLMAHLISTGLQNKKNILFGNMEEIYHFHNRIFLRELESCIDCPELVGRCFLER---- Q6PDM6_MOUSE Q6PDM6_MOUSE DNPLMAHLISTGLQNKKNILFGNMEEIYHFHNRIFLRELESCIDCPELVGRCFLER---- Q8C7Z1_MOUSE Q8C7Z1_MOUSE ------------------------------------------------------------ Q80U26_MOUSE Q80U26_MOUSE DNPLMAHLISTGLQNKKNILFGNMEEIYHFHNRIFLRELESCIDCPELVGRCFLER---- MCF2L_MOUSE MCF2L_MOUSE DNPLMAHLISTGLQNKKNILFGNMEEIYHFHNRNIPAGVESCIDCPELVGRCFLER---- Q003U3_MOUSE Q003U3_MOUSE DNPLMAHLISTGLQNKKNILFGNMEEIYHFHNRNIPAGVESCIDCPELVGRCFLER---- B5SNI0_OTOGA B5SNI0_OTOGA DNPLMTHLISTDLHNKKDILFGNMEEIYHFHNRIFLRELEGYVDCPELVGRCFLER---- B3KT13_HUMAN B3KT13_HUMAN DNPLMAHLLSTGLHNKKDVLFGNMEEIYHFHNRIFLRELENYTDCPELVGRCFLER---- A9X169_PAPAN A9X169_PAPAN -------------------------------------------DIPQGAGK--LHR---- B1MTD7_CALMO B1MTD7_CALMO DNPLMAHLLSTGLHNKKDVLFGNMEEIYHFHNRIFLRELENYIDCPELVGRCFLER---- Q5REI0_PONAB Q5REI0_PONAB DNPLMAHLLSTGLHNKKDVLFGNMEEIYHFHNRIFLRELENYTDCPELVGRCFLER---- B4DHD6_HUMAN B4DHD6_HUMAN DNPLMAHLLSTGLHNKKDVLFGNMEEIYHFHNRIFLRELENYTDCPELVGRCFLER---- B4DIL6_HUMAN B4DIL6_HUMAN DNPLMAHLLSTGLHNKKDVLFGNMEEIYHFHNRIFLRELENYTDCPELVGRCFLER---- B7Z9K4_HUMAN B7Z9K4_HUMAN DNPLMAHLLSTGLHNKKDVLFGNMEEIYHFHNRIFLRELENYTDCPELVGRCFLER---- MCF2L_HUMAN MCF2L_HUMAN DNPLMAHLLSTGLHNKKDVLFGNMEEIYHFHNRIFLRELENYTDCPELVGRCFLER---- A8MU87_HUMAN A8MU87_HUMAN DNPLMAHLLSTGLHNKKDVLFGNMEEIYHFHNRIFLRELENYTDCPELVGRCFLER---- B7ZBJ8_HUMAN B7ZBJ8_HUMAN DNPLMAHLLSTGLHNKKDVLFGNMEEIYHFHNRIFLRELENYTDCPELVGRCFLER---- B8A4Q9_DANRE B8A4Q9_DANRE ------------------------------------------------------------ Q4RY59_TETNG Q4RY59_TETNG DNPAMAHLIPNSLQNKKDILFGNMSEIYQFHKRTFLKELEAYTDCPELVGRCFLER---- Q4SVF8_TETNG Q4SVF8_TETNG EDPSLSDLLPSALHSQKDLLFGNMPEIYQ----VFLQDLQGCLETPERVGSCFLQR---- Q4RP67_TETNG Q4RP67_TETNG ENPALSSLLPPILHSKQDILFGNMPEIYNFHSRIFLQDLEGCLETPESVGACFLERVRQR Q7ZZ90_DANRE Q7ZZ90_DANRE DNPSLAPLLPTSLRNKRDVLFGNLPDIYNFHS---------------------------- MATCH CONSENSUS DNP?M??L????L?NKK??LFGNM?EIY?FH???F???LE?????PE?VG?CFLER????

MF2L2_HUMAN MF2L2_HUMAN ---------------------------------------KEDLQIYFKYHKNLPRARAIW A2AEU1_MOUSE A2AEU1_MOUSE ---------------------------------------KDDFQMYAKYCQNKPRSELIW Q8BLE2_MOUSE Q8BLE2_MOUSE ---------------------------------------KDDFQMYAKYCQNKPRSELIW Q99N72_MOUSE Q99N72_MOUSE ---------------------------------------KDDFQMYAKYCQNKPRSELIW Q7TNJ5_MOUSE Q7TNJ5_MOUSE ---------------------------------------KDDFQMYAKYCQNKPRSELIW Q8C067_MOUSE Q8C067_MOUSE ---------------------------------------KDDFQMYAKYCQNKPRSELIW A2AET8_MOUSE A2AET8_MOUSE ---------------------------------------KDDFQMYAKYCQNKPRSELIW B7Z3Y5_HUMAN B7Z3Y5_HUMAN ---------------------------------------KDDFQMYAKYCQNKPRSETIW Q5JYJ2_HUMAN Q5JYJ2_HUMAN ---------------------------------------KDDFQMYAKYCQNKPRSETIW B7Z3Z2_HUMAN B7Z3Z2_HUMAN ---------------------------------------KDDFQMYAKYCQNKPRSETIW B2R9S6_HUMAN B2R9S6_HUMAN ---------------------------------------KDDFQMYAKYCQNKPRSETIW B7Z869_HUMAN B7Z869_HUMAN ---------------------------------------KDDFQMYAKYCQNKPRSETIW B7ZAV1_HUMAN B7ZAV1_HUMAN ---------------------------------------KDDFQMYAKYCQNKPRSETIW Q5JYJ7_HUMAN Q5JYJ7_HUMAN ---------------------------------------KDDFQMYAKYCQNKPRSETIW Q5JYJ5_HUMAN Q5JYJ5_HUMAN ---------------------------------------KDDFQMYAKYCQNKPRSETIW Q5JYJ6_HUMAN Q5JYJ6_HUMAN ---------------------------------------KDDFQMYAKYCQNKPRSETIW Q5JYJ3_HUMAN Q5JYJ3_HUMAN ---------------------------------------KDDFQMYAKYCQNKPRSETIW MCF2_HUMAN MCF2_HUMAN ---------------------------------------KDDFQMYAKYCQNKPRSETIW Q4S0P7_TETNG Q4S0P7_TETNG ---------------------------------------MTDLQIYEKYCHNKPRSESLW B8A4Q6_DANRE B8A4Q6_DANRE ---------------------------------------MTDLQIYEKYCQNKPRSESLW MCF2L_RAT MCF2L_RAT ---------------------------------------MEEFQIYEKYCQNKPRSESLW Q3UHQ9_MOUSE Q3UHQ9_MOUSE ---------------------------------------MEEFQIYEKYCQNKPRSESLW Q6PDM6_MOUSE Q6PDM6_MOUSE ---------------------------------------MEEFQIYEKYCQNKPRSESLW Q8C7Z1_MOUSE Q8C7Z1_MOUSE ------------------------------------------------------------ Q80U26_MOUSE Q80U26_MOUSE ---------------------------------------MEEFQIYEKYCQNKPRSESLW MCF2L_MOUSE MCF2L_MOUSE ---------------------------------------MEEFQIYEKYCQNKPRSESLW Q003U3_MOUSE Q003U3_MOUSE ---------------------------------------MEEFQIYEKYCQNKPRSESLW B5SNI0_OTOGA B5SNI0_OTOGA ---------------------------------------MEDFQIYEKYCQNKPRSESLW B3KT13_HUMAN B3KT13_HUMAN ---------------------------------------MEDFQIYEKYCQNKPRSESLW A9X169_PAPAN A9X169_PAPAN ----------------------------------------------------LPRTG--W B1MTD7_CALMO B1MTD7_CALMO ---------------------------------------MEDFQIYEKYCQNKPRSESLW Q5REI0_PONAB Q5REI0_PONAB ---------------------------------------MEDFQIYEKYCQNKPRSESLW B4DHD6_HUMAN B4DHD6_HUMAN ---------------------------------------MEDFQIYEKYCQNKPRSESLW B4DIL6_HUMAN B4DIL6_HUMAN ---------------------------------------MEDLQIYEKYCQNKPRSESLW B7Z9K4_HUMAN B7Z9K4_HUMAN ---------------------------------------MEDFQIYEKYCQNKPRSESLW MCF2L_HUMAN MCF2L_HUMAN ---------------------------------------MEDFQIYEKYCQNKPRSESLW A8MU87_HUMAN A8MU87_HUMAN ---------------------------------------MEDFQIYEKYCQNKPRSESLW B7ZBJ8_HUMAN B7ZBJ8_HUMAN ---------------------------------------MEDFQIYEKYCQNKPRSESLW B8A4Q9_DANRE B8A4Q9_DANRE ------------------------------------------------------------ Q4RY59_TETNG Q4RY59_TETNG ---------------------------------------MKDLQIYEAYCQNKPRSESLW Q4SVF8_TETNG Q4SVF8_TETNG ---------------------------------------KEKFQVYERYCQNKPRSELLW Q4RP67_TETNG Q4RP67_TETNG KLFVNSQTFCLFACLFFFYFVLFKKVPFYTYSPPFESPQKESFQMYECYCQNKPRSDALW Q7ZZ90_DANRE Q7ZZ90_DANRE ------------------------------------------------------------ MATCH CONSENSUS ???????????????????????????????????????????Q?Y?KYCQNKPRSE??W

MF2L2_HUMAN MF2L2_HUMAN QECQDCAYFGVCQRQLDHNLPLFKYLKGPSQRLIKYQMLLKGLLDFESPEDMEIDPGELG A2AEU1_MOUSE A2AEU1_MOUSE RKYSECAFFQECQRKLKHRLGLDSYLLKPVQRITKYQLLLKELLKY-------------- Q8BLE2_MOUSE Q8BLE2_MOUSE RKYSECAFFQECQRKLKHRLGLDSYLLKPVQRITKYQLLLKELLKY-------------- Q99N72_MOUSE Q99N72_MOUSE RKYSECAFFQECQRKLKHRLGLDSYLLKPVQRITKYQLLLKELLKY-------------- Q7TNJ5_MOUSE Q7TNJ5_MOUSE RKYSECAFFQECQRKLKHRLGLDSYLLKPVQRITKYQLLLKELLKY-------------- Q8C067_MOUSE Q8C067_MOUSE RKYSECAFFQECQRKLKHRLGLDSYLLKPVQRITKYQLLLKELLKY-------------- A2AET8_MOUSE A2AET8_MOUSE RKYSECAFFQECQRKLKHRLGLDSYLLKPVQRITKYQLLLKELLKY-------------- B7Z3Y5_HUMAN B7Z3Y5_HUMAN RKYSECAFFQECQRKLKHRLRLDSYLLKPVQRITKYQLLLKELLKY-------------- Q5JYJ2_HUMAN Q5JYJ2_HUMAN RKYSECAFFQECQRKLKHRLRLDSYLLKPVQRITKYQLLLKELLKY-------------- B7Z3Z2_HUMAN B7Z3Z2_HUMAN RKYSECAFFQECQRKLKHRLRLDSYLLKPVQRITKYQLLLKELLKY-------------- B2R9S6_HUMAN B2R9S6_HUMAN RKYSECAFFQECQRKLKHRLRLDSYLLKPGQRITKYQLLLKELLKY-------------- B7Z869_HUMAN B7Z869_HUMAN RKYSECAFFQECQRKLKHRLRLDSYLLKPVQRITKYQLLLKELLKY-------------- B7ZAV1_HUMAN B7ZAV1_HUMAN RKYSECAFFQECQRKLKHRLRLDSYLLKPVQRITKYQLLLKELLKY-------------- Q5JYJ7_HUMAN Q5JYJ7_HUMAN RKYSECAFFQECQRKLKHRLRLDSYLLKPVQRITKYQLLLKELLKY-------------- Q5JYJ5_HUMAN Q5JYJ5_HUMAN RKYSECAFFQECQRKLKHRLRLDSYLLKPVQRITKYQLLLKELLKY-------------- Q5JYJ6_HUMAN Q5JYJ6_HUMAN RKYSECAFFQECQRKLKHRLRLDSYLLKPVQRITKYQLLLKELLKY-------------- Q5JYJ3_HUMAN Q5JYJ3_HUMAN RKYSECAFFQECQRKLKHRLRLDSYLLKPVQRITKYQLLLKELLKY-------------- MCF2_HUMAN MCF2_HUMAN RKYSECAFFQECQRKLKHRLRLDSYLLKPVQRITKYQLLLKELLKY-------------- Q4S0P7_TETNG Q4S0P7_TETNG RQCSDCAFFQECQKKLEHKLGLDSYLLKPVQRITKYQLLLKEMLKY-------------- B8A4Q6_DANRE B8A4Q6_DANRE RQCSDCAFFQECQKKLEHKLGLDSYLLKPVQRITKYQLLLKELLKY-------------- MCF2L_RAT MCF2L_RAT RQCSDCPFFQECQKKLDHKLSLDSYLLKPVQRITKYQLLLKEMLKY-------------- Q3UHQ9_MOUSE Q3UHQ9_MOUSE RQCSDCPFFQECQKKLDHKLSLDSYLLKPVQRITKYQLLLKEMLKY-------------- Q6PDM6_MOUSE Q6PDM6_MOUSE RQCSDCPFFQECQKKLDHKLSLDSYLLKPVQRITKYQLLLKEMLKY-------------- Q8C7Z1_MOUSE Q8C7Z1_MOUSE ------------------------------------------------------------ Q80U26_MOUSE Q80U26_MOUSE RQCSDCPFFQECQKKLDHKLSLDSYLLKPVQRITKYQLLLKEMLKY-------------- MCF2L_MOUSE MCF2L_MOUSE RQCSDCPFFQECQKKLDHKLSLDSYLLKPVQRITKYQLLLKEMLKY-------------- Q003U3_MOUSE Q003U3_MOUSE RQCSDCPFFQECQKKLDHKLSLDSYLLKPVQRITKYQLLLKEMLKY-------------- B5SNI0_OTOGA B5SNI0_OTOGA RQCSDCPFFQECQRKLDHKLSLDSYLLKPVQRITKYQLLLKEMLKY-------------- B3KT13_HUMAN B3KT13_HUMAN RQCSDCPFFQECQRKLDHKLSLDSYLLKPVQRITKYQLLLKEMLKY-------------- A9X169_PAPAN A9X169_PAPAN KMLS-------------------------------------------------------- B1MTD7_CALMO B1MTD7_CALMO RQCSDCPFFQECQRKLDHKLSLDSYLLKPVQRVTKYQLLLKEMLKY-------------- Q5REI0_PONAB Q5REI0_PONAB RQCSDCPFFQECQRKLDHKLSLDSYLLKPVQRITKYQLLLKEMLKY-------------- B4DHD6_HUMAN B4DHD6_HUMAN RQCSDCPFFQECQRKLDHKLSLDSYLLKPVQRITKYQLLLKEMLKY-------------- B4DIL6_HUMAN B4DIL6_HUMAN RQCSDCPFFQECQRKLDHKLSLDSYLLKPVQRITKYQLLLKEMLKY-------------- B7Z9K4_HUMAN B7Z9K4_HUMAN RQCSDCPFFQECQRKLDHKLSLDSYLLKPVQRITKYQLLLKEMLKY-------------- MCF2L_HUMAN MCF2L_HUMAN RQCSDCPFFQECQRKLDHKLSLDSYLLKPVQRITKYQLLLKEMLKY-------------- A8MU87_HUMAN A8MU87_HUMAN RQCSDCPFFQECQRKLDHKLSLDSYLLKPVQRITKYQLLLKEMLKY-------------- B7ZBJ8_HUMAN B7ZBJ8_HUMAN RQCSDCPFFQECQRKLDHKLSLDSYLLKPVQRITKYQLLLKEMLKY-------------- B8A4Q9_DANRE B8A4Q9_DANRE ------------------------------------------------------------ Q4RY59_TETNG Q4RY59_TETNG RQCSDCAFFQECQKKLEHKLGLDSYLLKPVQRITKYQLLLKELLKY-------------- Q4SVF8_TETNG Q4SVF8_TETNG RQCCDSPFFQECQKKLEHKLGLDSYLLKPVQRLTKYQLLLKELLKH-------------- Q4RP67_TETNG Q4RP67_TETNG RQFSDCHFFQECQKNLEHKLGLDSYLLKPVQRLTKYQLLLKELLKY-------------- Q7ZZ90_DANRE Q7ZZ90_DANRE ------------------------------------------------------------ MATCH CONSENSUS R??S?C?FFQECQ?KL?H?L?LDSYLLKPVQRITKYQLLLKE?LKY??????????????

MF2L2_HUMAN MF2L2_HUMAN GSAKDGPKRTKDSAFSTELQQALAVIEDLIKSCELAVDLAAVTECP-------------- A2AEU1_MOUSE A2AEU1_MOUSE ---------SKEGEGTTKLKEALDSMLELLKSVNDSMHQTAINGYV-------------- Q8BLE2_MOUSE Q8BLE2_MOUSE ---------SKEGEGTTKLKEALDSMLELLKSVNDSMHQTAINGYV-------------- Q99N72_MOUSE Q99N72_MOUSE ---------SKEGEGTTKLKEALDSMLELLKSVNDSMHQTAINAYV-------------- Q7TNJ5_MOUSE Q7TNJ5_MOUSE ---------SKEGEGTTKLKEALDSMLELLKSVNDSMHQTAINAYV-------------- Q8C067_MOUSE Q8C067_MOUSE ---------SKEGEGTTKLKEALDSMLELLKSVNDSMHQTAINGYV-------------- A2AET8_MOUSE A2AET8_MOUSE ---------SKEGEGTTKLKEALDSMLELLKSVNDSMHQTAINGYV-------------- B7Z3Y5_HUMAN B7Z3Y5_HUMAN ---------SKDCEGSALLKKALDAMLDLLKSVNDSMHQIAINGYI-------------- Q5JYJ2_HUMAN Q5JYJ2_HUMAN ---------SKDCEGSALLKKALDAMLDLLKSVNDSMHQIAINGYI-------------- B7Z3Z2_HUMAN B7Z3Z2_HUMAN ---------SKDCEGSALLKKALDAMLDLLKSVNDSMHQIAINGYI-------------- B2R9S6_HUMAN B2R9S6_HUMAN ---------SKDCEGSALLKKALDAMLDLLKSVNDSMHQIAINGYI-------------- B7Z869_HUMAN B7Z869_HUMAN ---------SKDCEGSALLKKALDAMLDLLKSVNDSMHQIAINGYI-------------- B7ZAV1_HUMAN B7ZAV1_HUMAN ---------SKDCEGSALLKKALDAMLDLLKSVNDSMHQIAINGYI-------------- Q5JYJ7_HUMAN Q5JYJ7_HUMAN ---------SKDCEGSALLKKALDAMLDLLKSVNDSMHQIAINGYI-------------- Q5JYJ5_HUMAN Q5JYJ5_HUMAN ---------SKDCEGSALLKKALDAMLDLLKSVNDSMHQIAINGYI-------------- Q5JYJ6_HUMAN Q5JYJ6_HUMAN ---------SKDCEGSALLKKALDAMLDLLKSVNDSMHQIAINGYI-------------- Q5JYJ3_HUMAN Q5JYJ3_HUMAN ---------SKDCEGSALLKKALDAMLDLLKSVNDSMHQIAINGYI-------------- MCF2_HUMAN MCF2_HUMAN ---------SKDCEGSALLKKALDAMLDLLKSVNDSMHQIAINGYI-------------- Q4S0P7_TETNG Q4S0P7_TETNG ---------SKTCEGADDLQEALASILGILKAVNDSMHLIAITGYE-------------- B8A4Q6_DANRE B8A4Q6_DANRE ---------SKGCEGEEDLQEALSSILGILKAVNDSMHLIAITGYE-------------- MCF2L_RAT MCF2L_RAT ---------SKHCEGAEDLQEALSSILGILKAVNDSMHLIAITGYD-------------- Q3UHQ9_MOUSE Q3UHQ9_MOUSE ---------SKHCEGAEDLQEALSSILGILKAVNDSMHLIAITGYD-------------- Q6PDM6_MOUSE Q6PDM6_MOUSE ---------SKHCEGAEDLQEALSSILGILKAVNDSMHLIAITGYD-------------- Q8C7Z1_MOUSE Q8C7Z1_MOUSE ------------------------------------------------------------ Q80U26_MOUSE Q80U26_MOUSE ---------SKHCEGAEDLQEALSSILGILKAVNDSMHLIAITGYD-------------- MCF2L_MOUSE MCF2L_MOUSE ---------SKHCEGAEDLQEALSSILGILKAVNDSMHLIAITGYD-------------- Q003U3_MOUSE Q003U3_MOUSE ---------SKHCEGAEDLQEALSSILGILKAVNDSMHLIAITGYD-------------- B5SNI0_OTOGA B5SNI0_OTOGA ---------SKSCEGAEGLQEALSSILGILKAVNDSMHLIAITGYD-------------- B3KT13_HUMAN B3KT13_HUMAN ---------SRNCEGAEDLQEALSSILGILKAVNDSMHLIAITGYD-------------- A9X169_PAPAN A9X169_PAPAN ------------------------------------------------------------ B1MTD7_CALMO B1MTD7_CALMO ---------SKNCEGAEDLQEALSSILGILKAVNDSMHLIAITGYD-------------- Q5REI0_PONAB Q5REI0_PONAB ---------SKNCEGAEDLQEALSSILGILKAVNDSMHLIAITGYD-------------- B4DHD6_HUMAN B4DHD6_HUMAN ---------SRNCEGAEDLQEALSSILGILKAVNDSMHLIAITGYD-------------- B4DIL6_HUMAN B4DIL6_HUMAN ---------SRNCEGAEDLQEALSSILGILKAVNDSMHLIAITGYD-------------- B7Z9K4_HUMAN B7Z9K4_HUMAN ---------SRNCEGAEDLQEALSSILGILKAVNDSMHLIAITGYD-------------- MCF2L_HUMAN MCF2L_HUMAN ---------SRNCEGAEDLQEALSSILGILKAVNDSMHLIAITGYD-------------- A8MU87_HUMAN A8MU87_HUMAN ---------SRNCEGAEDLQEALSSILGILKAVNDSMHLIAITGYD-------------- B7ZBJ8_HUMAN B7ZBJ8_HUMAN ---------SRNCEGAEDLQEALSSILGILKAVNDSMHLIAITGYD-------------- B8A4Q9_DANRE B8A4Q9_DANRE ------------------------------------------------------------ Q4RY59_TETNG Q4RY59_TETNG ---------SRGCEGCDDLQEALTSILGILKAVNDSMHLIAITGYEVRSGLVLACSGAHE Q4SVF8_TETNG Q4SVF8_TETNG ---------CREERYRQQLQEALDSMLELLKSVNDSMHQIAITGYQ-------------- Q4RP67_TETNG Q4RP67_TETNG ---------STDCKGTSELQGALTAMLDLLKSVNDSMHQIAITGYE-------------- Q7ZZ90_DANRE Q7ZZ90_DANRE ------------------------------------------------------------ MATCH CONSENSUS ?????????S???EG???L??AL???L??LK?VNDSMH??AI?GY???????????????

MF2L2_HUMAN MF2L2_HUMAN ------------------------DDIGKLGKLLLHGPFSVWTIHKDRY-KMKDLIRFKP A2AEU1_MOUSE A2AEU1_MOUSE ------------------------GNINELGKMVLQGSFNVWLGHRKGATKMKDFARFKP Q8BLE2_MOUSE Q8BLE2_MOUSE ------------------------GNINELGKMVLQGSFNVWLGHRKGATKMKDFARFKP Q99N72_MOUSE Q99N72_MOUSE ------------------------GNINELGKMVLQGSFNVWLGHRKGATKMKDFARFKP Q7TNJ5_MOUSE Q7TNJ5_MOUSE ------------------------GNINELGKMVLQGSFNVWLGHRKGATKMKDFARFKP Q8C067_MOUSE Q8C067_MOUSE ------------------------GNINELGKMVLQGSFNVWLGHRKGATKMKDFARFKP A2AET8_MOUSE A2AET8_MOUSE ------------------------GNINELGKMVLQGSFNVWLGHRKGATKMKDFARFKP B7Z3Y5_HUMAN B7Z3Y5_HUMAN ------------------------GNLNELGKMIMQGGFSVWIGHKKGATKMKDLARFKP Q5JYJ2_HUMAN Q5JYJ2_HUMAN ------------------------GNLNELGKMIMQGGFSVWIGHKKGATKMKDLARFKP B7Z3Z2_HUMAN B7Z3Z2_HUMAN ------------------------GNLNELGKMIMQGGFSVWIGHKKGATKMKDLARFKP B2R9S6_HUMAN B2R9S6_HUMAN ------------------------GNLNELGKMIMQGGFSVWIGHKKGATKMKDLARFKP B7Z869_HUMAN B7Z869_HUMAN ------------------------GNLNELGKMIMQGGFSVWIGHKKGATKMKDLARFKP B7ZAV1_HUMAN B7ZAV1_HUMAN ------------------------GILNELGKMIMQGGFSVWIGHKKGATKMKDLARFKP Q5JYJ7_HUMAN Q5JYJ7_HUMAN ------------------------GNLNELGKMIMQGGFSVWIGHKKGATKMKDLARFKP Q5JYJ5_HUMAN Q5JYJ5_HUMAN ------------------------GNLNELGKMIMQGGFSVWIGHKKGATKMKDLARFKP Q5JYJ6_HUMAN Q5JYJ6_HUMAN ------------------------GNLNELGKMIMQGGFSVWIGHKKGATKMKDLARFKP Q5JYJ3_HUMAN Q5JYJ3_HUMAN ------------------------GNLNELGKMIMQGGFSVWIGHKKGATKMKDLARFKP MCF2_HUMAN MCF2_HUMAN ------------------------GNLNELGKMIMQGGFSVWIGHKKGATKMKDLARFKP Q4S0P7_TETNG Q4S0P7_TETNG ------------------------GNLSELGKLLMQGSFSVWTEHKKGHAKVKDLARFKP B8A4Q6_DANRE B8A4Q6_DANRE ------------------------GNLSDLGRLMMQGSFSVWTEHKKGHAKVKDLARFKP MCF2L_RAT MCF2L_RAT ------------------------GNLGDLGKLLMQGSFSVWTDHKKGHTKVKELARFKP Q3UHQ9_MOUSE Q3UHQ9_MOUSE ------------------------GNLGDLGKLLMQGSFSVWTDHKKGHTKVKELARFKP Q6PDM6_MOUSE Q6PDM6_MOUSE ------------------------GNLGDLGKLLMQGSFSVWTDHKKGHTKVKELARFKP Q8C7Z1_MOUSE Q8C7Z1_MOUSE ------------------------------------------------------------ Q80U26_MOUSE Q80U26_MOUSE ------------------------GNLGDLGKLLMQGSFSVWTDHKKGHTKVKELARFKP MCF2L_MOUSE MCF2L_MOUSE ------------------------GNLGDLGKLLMQGSFSVWTDHKKGHTKVKELARFKP Q003U3_MOUSE Q003U3_MOUSE ------------------------GNLGDLGKLLMQGSFSVWTDHKKGHTKVKELARFKP B5SNI0_OTOGA B5SNI0_OTOGA ------------------------GNLGDLGRLLMQGSFSVWTDHKRGHTKVKELARFKP B3KT13_HUMAN B3KT13_HUMAN ------------------------GNLGDLGKLLMQGSFSVWTDHKRGHTKVKELARFKP A9X169_PAPAN A9X169_PAPAN ------------------------------------------------------------ B1MTD7_CALMO B1MTD7_CALMO ------------------------GNLGDLGKLLMQGSFSVWTDHKRGHTKVKELARFKP Q5REI0_PONAB Q5REI0_PONAB ------------------------GNLGDLGKLLMQGSFSVWTDHKRGHTKVKELARFKP B4DHD6_HUMAN B4DHD6_HUMAN ------------------------GNLGDLGKLLMQGSFSVWTDHKRGHTKVKELARFKP B4DIL6_HUMAN B4DIL6_HUMAN ------------------------GNLGDLGKLLMQGSFSVWTDHKRGHTKVKELARFKP B7Z9K4_HUMAN B7Z9K4_HUMAN ------------------------GNLGDLGKLLMQGSFSVWTDHKRGHTKVKELARFKP MCF2L_HUMAN MCF2L_HUMAN ------------------------GNLGDLGKLLMQGSFSVWTDHKRGHTKVKELARFKP A8MU87_HUMAN A8MU87_HUMAN ------------------------GNLGDLGKLLMQGSFSVWTDHKRGHTKVKELARFKP B7ZBJ8_HUMAN B7ZBJ8_HUMAN ------------------------GNLGDLGKLLMQGSFSVWTDHKRGHTKVKELARFKP B8A4Q9_DANRE B8A4Q9_DANRE ------------------------------------------------------------ Q4RY59_TETNG Q4RY59_TETNG VATGWASVNLQKVDCKTSLLFLFQGNLSELGRLLMQGSFSVWTEHKKGHAKVKDLARFKP Q4SVF8_TETNG Q4SVF8_TETNG ------------------------GDLSQLGRVVLQGGFSVWISHKRAAVRMKEMARFKP Q4RP67_TETNG Q4RP67_TETNG ------------------------GDICELGRVLMQGSFSVWISHKRGPTRMKELARFKP Q7ZZ90_DANRE Q7ZZ90_DANRE ---------------------------------------------RQGHTQ--------- MATCH CONSENSUS ????????????????????????GN???LG????QG?F?VW??H??G?TK?K??ARFKP

MF2L2_HUMAN MF2L2_HUMAN SQRQIYLFERGIVFCKIRMEPGD-QGLSPHYSFKKAMKLMTLSIRQLGRGSHRKFEIASR A2AEU1_MOUSE A2AEU1_MOUSE MQRHLFLYEKAVMFCKRRFESGEGADRYPSYSFKHCLKMEDVGITEHVKGDNRKFEIRYS Q8BLE2_MOUSE Q8BLE2_MOUSE MQRHLFLYEKAVMFCKRRFESGEGADRYPSYSFKHCLKMEDVGITEHVKGDNRKFEIRYS Q99N72_MOUSE Q99N72_MOUSE MQRHLFLYEKAVMFCKRRFESGEGADRYPSYSFKHCLKMEDVGITEHVKGDNRKFEIRYS Q7TNJ5_MOUSE Q7TNJ5_MOUSE MQRHLFLYEKAVMFCKRRFESGEGADRYPSYSFKHCLKMEDVGITEHVKGDNRKFEIRYS Q8C067_MOUSE Q8C067_MOUSE MQRHLFLYEKAVMFCKRRFESGEGADRYPSYSFKHCLKMEDVGITEHVKGDNRKFEIRYS A2AET8_MOUSE A2AET8_MOUSE MQRHLFLYEKAVMFCKRRFESGEGADRYPSYSFKHCLKMEDVGITEHVKGDNRKFEIRYS B7Z3Y5_HUMAN B7Z3Y5_HUMAN MQRHLFLYEKAIVFCKRRVESGEGSDRYPSYSFKHCWKMDEVGITEYVKGDNRKFEIWYG Q5JYJ2_HUMAN Q5JYJ2_HUMAN MQRHLFLYEKAIVFCKRRVESGEGSDRYPSYSFKHCWKMDEVGITEYVKGDNRKFEIWYG B7Z3Z2_HUMAN B7Z3Z2_HUMAN MQRHLFLYEKAIVFCKRRVESGEGSDRYPSYSFKHCWKMDEVGITEYVKGDNRKFEIWYG B2R9S6_HUMAN B2R9S6_HUMAN MQRHLFLYEKAIVFCKRRVESGEGSDRYPSYSFKHCWKMDEVGITEYVKGDNRKFEIWYG B7Z869_HUMAN B7Z869_HUMAN MQRHLFLYEKAIVFCKRRVESGEGSDRYPSYSFKHCWKMDEVGITEYVKGDNRKFEIWYG B7ZAV1_HUMAN B7ZAV1_HUMAN MQRHLFLYEKAIVFCKRRVESGEGSDRYPSYSFKHCWKMDEVGITEYVKGDNRKFEIWYG Q5JYJ7_HUMAN Q5JYJ7_HUMAN MQRHLFLYEKAIVFCKRRVESGEGSDRYPSYSFKHCWKMDEVGITEYVKGDNRKFEIWYG Q5JYJ5_HUMAN Q5JYJ5_HUMAN MQRHLFLYEKAIVFCKRRVESGEGSDRYPSYSFKHCWKMDEVGITEYVKGDNRKFEIWYG Q5JYJ6_HUMAN Q5JYJ6_HUMAN MQRHLFLYEKAIVFCKRRVESGEGSDRYPSYSFKHCWKMDEVGITEYVKGDNRKFEIWYG Q5JYJ3_HUMAN Q5JYJ3_HUMAN MQRHLFLYEKAIVFCKRRVESGEGSDRYPSYSFKHCWKMDEVGITEYVKGDNRKFEIWYG MCF2_HUMAN MCF2_HUMAN MQRHLFLYEKAIVFCKRRVESGEGSDRYPSYSFKHCWKMDEVGITEYVKGDNRKFEIWYG Q4S0P7_TETNG Q4S0P7_TETNG MQRHLFLHEKALLFCKRREENGEGYEKAPSYSFKHSLSMSAVGITENAKGDNKKFEIWCK B8A4Q6_DANRE B8A4Q6_DANRE MQRHLFLHEKALLFCKKREENGEGYEKAPSYSFKHSLSMSAVGITENAKGDNKKFEIWCN MCF2L_RAT MCF2L_RAT MQRHLFLHEKAVLFCKKREENGEGYEKAPSYSYKQSLNMTAVGITENVKGDTKKFEIWYN Q3UHQ9_MOUSE Q3UHQ9_MOUSE MQRHLFLHEKAVLFCKKREENGEGYEKAPSYSYKQSLNMTAVGITENVKGDTKKFETWYN Q6PDM6_MOUSE Q6PDM6_MOUSE MQRHLFLHEKAVLFCKKREENGEGYEKAPSYSYKQSLNMTAVGITENVKGDTKKFEIWYN Q8C7Z1_MOUSE Q8C7Z1_MOUSE ------------------------------------------------------------ Q80U26_MOUSE Q80U26_MOUSE MQRHLFLHEKAVLFCKKREENGEGYEKAPSYSYKQSLNMTAVGITENVKGDTKKFEIWYN MCF2L_MOUSE MCF2L_MOUSE MQRHLFLHEKAVLFCKKREENGEGYEKAPSYSYKQSLNMTAVGITENVKGDTKKFEIWYN Q003U3_MOUSE Q003U3_MOUSE MQRHLFLHEKAVLFCKKREENGEGYEKAPSYSYKQSLNMTAVGITENVKGDTKKFEIWYN B5SNI0_OTOGA B5SNI0_OTOGA MQRHLFLHEKAVLFCKKREENGEGYEKAPSYSYKQSLDMTAVGITENVKGDAKKFEIWYN B3KT13_HUMAN B3KT13_HUMAN MQRHLFLHEKAVLFCKKREEDG---GLGPKKLVPTQPPVEPTRGCTFLRGDSPH------ A9X169_PAPAN A9X169_PAPAN ------------------------------------------------------------ B1MTD7_CALMO B1MTD7_CALMO MQRHLFLHEKAVLFCKKREENGEGYEKAPSYSYKQSLNMAAVGITENVKGDAKKFEIWYN Q5REI0_PONAB Q5REI0_PONAB MQRHLFLHEKAVLFCKKREENGEGYEKAPSYSYKQSLNMAAVGITENVKGDAKKFEIWYN B4DHD6_HUMAN B4DHD6_HUMAN MQRHLFLHEKAVLFCKKREENGEGYEKAPSYSYKQSLNMAAVGITENVKGDAKKFEIWYN B4DIL6_HUMAN B4DIL6_HUMAN MQRHLFLHEKAVLFCKKREENGEGYEKAPSYSYKQSLNMAAVGITENVKGDAKKFEIWYN B7Z9K4_HUMAN B7Z9K4_HUMAN MQRHLFLHEKAVLFCKKREENGEGYEKAPSYSYKQSLNMAAVGITENVKGDAKKFEIWYN MCF2L_HUMAN MCF2L_HUMAN MQRHLFLHEKAVLFCKKREENGEGYEKAPSYSYKQSLNMAAVGITENVKGDAKKFEIWYN A8MU87_HUMAN A8MU87_HUMAN MQRHLFLHEKAVLFCKKREENGEGYEKAPSYSYKQSLNMAAVGITENVKGDAKKFEIWYN B7ZBJ8_HUMAN B7ZBJ8_HUMAN MQRHLFLHEKAVLFCKKREENGEGYEKAPSYSYKQSLNMAAVGITENVKGDAKKFEIWYN B8A4Q9_DANRE B8A4Q9_DANRE ------------------------------------------------------------ Q4RY59_TETNG Q4RY59_TETNG MQRHLFLHEKALLFCKRREENGEGYEKAPSYSFKHSLSMSAVGITENAKGDNKKFEIWCN Q4SVF8_TETNG Q4SVF8_TETNG MQRHLFLYEHAVLFCKRRDE--DSPDRTPFYSFKSCLRLSAVGVTESVKGDVRKFEICYS Q4RP67_TETNG Q4RP67_TETNG MQRHLFLYERALLFCKRREEHGDGGDKTPSYSFKHCLKMTAVGITENVKGDQKKFEIWYS Q7ZZ90_DANRE Q7ZZ90_DANRE ------------------------------------------------------------ MATCH CONSENSUS MQRHLFL?EKA??FCK?R?E?GEG????PSYS?K????M??VGITE??KGD??KFEI???

MF2L2_HUMAN MF2L2_HUMAN NGLEKYILQAASK-EIRDCWFSEISKLLMEQ--QNNIKDQG-NPQFEMSTSKGSG----- A2AEU1_MOUSE A2AEU1_MOUSE EKEEIYIVQAPNV-DVKMLWLKEIRKILVQQ--KELMTAK--TQQDQALDQDQL--FPQQ Q8BLE2_MOUSE Q8BLE2_MOUSE EKEEIYIVQAPNV-DVKMLWLKEIRKILVQQ--KELMTAK--TQQDQALDQDQL--FPQQ Q99N72_MOUSE Q99N72_MOUSE EKEEIYIVQAPNV-DVKMLWLKEIRKILVQQ--KELMTAK--TQQDQALDQDQL--FPQQ Q7TNJ5_MOUSE Q7TNJ5_MOUSE EKEEIYIVQAPNV-DVKMLWLKEIRKILVQQ--KELMTAK--TQQDQALDQDQL--FPQQ Q8C067_MOUSE Q8C067_MOUSE EKEEIYIVQAPNV-DVKMLWLKEIRKILVQQ--KELMTAK--TQQDQALDQDQL--FPQQ A2AET8_MOUSE A2AET8_MOUSE EKEEIYIVQAPNV-DVKMLWLKEIRKILVQQ--KELMTAK--TQQDQALDQDQL--FPQQ B7Z3Y5_HUMAN B7Z3Y5_HUMAN EKEEVYIVQASNV-DVKMTWLKEIRNILLKQ--QELLTVKKRKQQDQLTERDKF--QISL Q5JYJ2_HUMAN Q5JYJ2_HUMAN EKEEVYIVQASNV-DVKMTWLKEIRNILLKQ--QELLTVKKRKQQDQLTERDKFQISLQQ B7Z3Z2_HUMAN B7Z3Z2_HUMAN EKEEVYIVQASNV-DVKMTWLKEIRNILLKQ--QELLTVKKRKQQDQLTERDKFQISLQQ B2R9S6_HUMAN B2R9S6_HUMAN EKEEVYIVQASNV-DVKMTWLKEIRNILLKQ--QELLTVKKRKQQDQLTERDKF--QISL B7Z869_HUMAN B7Z869_HUMAN EKEEVYIVQASNV-DVKMTWLKEIRNILLKQ--QELLTVKKRKQQDQLTERDKF--QISL B7ZAV1_HUMAN B7ZAV1_HUMAN EKEEVYIVQASNV-DVKMTWLKEIRNILLKQ--QELLTVKKRKQQDQLTERDKF--QISL Q5JYJ7_HUMAN Q5JYJ7_HUMAN EKEEVYIVQASNV-DVKMTWLKEIRNILLKQ--QELLTVKKRKQQDQLTERDKF--QISL Q5JYJ5_HUMAN Q5JYJ5_HUMAN EKEEVYIVQASNV-DVKMTWLKEIRNILLKQ--QELLTVKKRKQQDQLTERDKF--QISL Q5JYJ6_HUMAN Q5JYJ6_HUMAN EKEEVYIVQASNV-DVKMTWLKEIRNILLKQ--QELLTVKKRKQQDQLTERDKF--QISL Q5JYJ3_HUMAN Q5JYJ3_HUMAN EKEEVYIVQASNV-DVKMTWLKEIRNILLKQ--QELLTVKKRKQQDQLTERDKF--QISL MCF2_HUMAN MCF2_HUMAN EKEEVYIVQASNV-DVKMTWLKEIRNILLKQ--QELLTVKKRKQQDQLTERDKF--QISL Q4S0P7_TETNG Q4S0P7_TETNG SREEVYIVQAPTA-DVKTTWVNEIRKVLTTQ----LEACRG-IQREHLVKHSNKMSLEAF B8A4Q6_DANRE B8A4Q6_DANRE SREEVYIVQASTP-EIKTAWVNEIRKVLTRQ----LKACREASQQKSSDQISPLTPSSTG MCF2L_RAT MCF2L_RAT AREEVYIIQAPTP-EIKAAWVNEIRKVLTSQ----LQACRE-ASQHRALEQSHSLPLPTP Q3UHQ9_MOUSE Q3UHQ9_MOUSE AREEVYIIQAPTP-EIKAAWVNEIRKVLTSQ----LQACRE-ASQHRALEQSHSLPLPTP Q6PDM6_MOUSE Q6PDM6_MOUSE AREEVYIIQAPTP-EIKAAWVNEIRKVLTSQ----LQACRE-ASQHRALEQSHSLPLPTP Q8C7Z1_MOUSE Q8C7Z1_MOUSE ------------------------------------------------------------ Q80U26_MOUSE Q80U26_MOUSE AREEVYIIQAPTP-EIKAAWVNEIRKVLTSQ----LQACRE-ASQHRALEQSHSLPLPTP MCF2L_MOUSE MCF2L_MOUSE AREEVYIIQAPTP-EIKAAWVNEIRKVLTSQ----LQACRE-ASQHRALEQSHSLPLPTP Q003U3_MOUSE Q003U3_MOUSE AREEVYIIQAPTP-EIKAAWVNEIRKVLTSQ----LQACRE-ASQHRALEQSHSLPLPTP B5SNI0_OTOGA B5SNI0_OTOGA AREEVYIIQAPTP-EIKAAWVNEIRKVLTSQ----LQACRE-ASQHRALEQSQSLPLPAS B3KT13_HUMAN B3KT13_HUMAN -PPTLYVIE--------------------------------------------------- A9X169_PAPAN A9X169_PAPAN ------------------------------------------------------------ B1MTD7_CALMO B1MTD7_CALMO AREEVYIVQAPTL-EIKAAWVNEIRKVLTSQ----LQACRE-ASQHRALEQSHSLPLPAP Q5REI0_PONAB Q5REI0_PONAB AREEVYIVQAPTP-EIKAAWVNEIRKVLTGQ----LQACRE-ASQHRALEQSQSLPLPAQ B4DHD6_HUMAN B4DHD6_HUMAN AREEVYIVQAPTP-EIKAAWVNEIRKVLTSQ----LQACRE-ASQHRALEQSQSLPLPAP B4DIL6_HUMAN B4DIL6_HUMAN AREEVYIVQAPTP-EIKAAWVNEIRKVLTSQ----LQACRE-ASQHRALEQSQSLPLPAP B7Z9K4_HUMAN B7Z9K4_HUMAN AREEVYIVQAPTP-EIKAAWVNEIRKVLTSQ----LQACRE-ASQHRALEQSQSLPLPAP MCF2L_HUMAN MCF2L_HUMAN AREEVYIVQAPTP-EIKAAWVNEIRKVLTSQ----LQACRE-ASQHRALEQSQSLPLPAP A8MU87_HUMAN A8MU87_HUMAN AREEVYIVQAPTP-EIKAAWVNEIRKVLTSQ----LQACRE-ASQHRALEQSQSLPLPAP B7ZBJ8_HUMAN B7ZBJ8_HUMAN AREEVYIVQAPTP-EIKAAWVNEIRKVLTSQ----LQACRE-ASQHRALEQSQSLPLPAP B8A4Q9_DANRE B8A4Q9_DANRE ------------------------------------------------------------ Q4RY59_TETNG Q4RY59_TETNG SRDEVFIVQAPTT-EIKSAWVNEIRKVLTQQ----LQACRD-ASQQKNSEPVSSSPTSNH Q4SVF8_TETNG Q4SVF8_TETNG GREVVYIVQMRLPLSPTTAWPVAAHSVAICEGLEDWGAATDFSNISDSDEDDQP------ Q4RP67_TETNG Q4RP67_TETNG GREEVYVVQGRAA---------------IQRGTQGLPATA--GLSPAVNQRLSLPAFPNK Q7ZZ90_DANRE Q7ZZ90_DANRE -------------------------RILEQQ----------------------------- MATCH CONSENSUS ??EE?YI?QA??????K??W??EIR??L??Q????L????????Q???????????????

MF2L2_HUMAN MF2L2_HUMAN ------------------------AGSGPWIKNMERATTSKEDPASSTGGIKG-CSSREF A2AEU1_MOUSE A2AEU1_MOUSE QN----------------------------------AELCKSSPFC----VCE-ETLFNA Q8BLE2_MOUSE Q8BLE2_MOUSE QN----------------------------------AELCKSSPFC----VCE-ETLFNA Q99N72_MOUSE Q99N72_MOUSE QN----------------------------------AELCKSSPFC----VCE-ETLFNA Q7TNJ5_MOUSE Q7TNJ5_MOUSE QN----------------------------------AELCKSSPFC----VCE-ETLFNA Q8C067_MOUSE Q8C067_MOUSE QN----------------------------------AELCKSSPFC----VCE-ETLFNA A2AET8_MOUSE A2AET8_MOUSE QN----------------------------------AELCKSSPFC----VCE-ETLFNA B7Z3Y5_HUMAN B7Z3Y5_HUMAN QQ----------------------------------NDE--------------------- Q5JYJ2_HUMAN Q5JYJ2_HUMAN ND----------------------------------EDLCRR------------------ B7Z3Z2_HUMAN B7Z3Z2_HUMAN ND----------------------------------EDLCRR------------------ B2R9S6_HUMAN B2R9S6_HUMAN QQ----------------------------------NDEKQQGAFI----STE-ET---- B7Z869_HUMAN B7Z869_HUMAN QQ----------------------------------NDEKQQGAFI----STE-ET---- B7ZAV1_HUMAN B7ZAV1_HUMAN QQ----------------------------------NDEKQQGAFI----STE-ET---- Q5JYJ7_HUMAN Q5JYJ7_HUMAN QQ----------------------------------NDEKQQGAFI----STE-ET---- Q5JYJ5_HUMAN Q5JYJ5_HUMAN QQ----------------------------------NDEKQQGAFI----STE-ET---- Q5JYJ6_HUMAN Q5JYJ6_HUMAN QQ----------------------------------NDEKQQGAFI----STE-ET---- Q5JYJ3_HUMAN Q5JYJ3_HUMAN QQ----------------------------------NDEKQQGAFI----STE-ET---- MCF2_HUMAN MCF2_HUMAN QQ----------------------------------NDEKQQGAFI----STE-ET---- Q4S0P7_TETNG Q4S0P7_TETNG GTLPKTNIVLQKPASRGQRSQDFLPPFKSGQRSFKKPEEKKAEPGSTDAMSSF-SPKPTG B8A4Q6_DANRE B8A4Q6_DANRE LT---------------------LSPFKTNPKSLKKGDEKKTEPTTTDPSS---AALFKN MCF2L_RAT MCF2L_RAT AS---------------------TSPTKGSTRNVKKLEDRKTDPLCLEG-CVS-SSLPKP Q3UHQ9_MOUSE Q3UHQ9_MOUSE SS---------------------TSPTKGNTRNVKKLEDRKTDPLSLEGYVSS-S-LPKP Q6PDM6_MOUSE Q6PDM6_MOUSE SS---------------------TSPTKGNTRNVKKLEDRKTDPLSLEGYVS--SSLPKP Q8C7Z1_MOUSE Q8C7Z1_MOUSE ------------------------------------------------------------ Q80U26_MOUSE Q80U26_MOUSE SS---------------------TSPTKGNTRNVKKLEDRKTDPLSLEGYVS--SSLPKP MCF2L_MOUSE MCF2L_MOUSE SS---------------------TSPTKGNTRNVKKLEDRKTDPLSLEGYVS--SSLPKP Q003U3_MOUSE Q003U3_MOUSE SS---------------------TSPTKGNTRNVKKLEDRKTDPLSLEGYVS--SSLPKP B5SNI0_OTOGA B5SNI0_OTOGA SN---------------------TSPLQGNTRNIKKLEERKTDPLSLEGYVSP-APLPKP B3KT13_HUMAN B3KT13_HUMAN --------------------------------------------------CCH------- A9X169_PAPAN A9X169_PAPAN ------------------------------------------------------------ B1MTD7_CALMO B1MTD7_CALMO TG---------------------TSPSRGNSRNIKKLEERKTDPLSLEGYGSS-APLSKP Q5REI0_PONAB Q5REI0_PONAB TS---------------------------------------TSPSR-------------- B4DHD6_HUMAN B4DHD6_HUMAN TS---------------------TSPSRGNSRNIKKLEERKTDPLSLEGYVSS-APLTKP B4DIL6_HUMAN B4DIL6_HUMAN TS---------------------TSPSRGNSRNIKKLEERKTDPLSLEGYVSS-APLTKP B7Z9K4_HUMAN B7Z9K4_HUMAN TS---------------------------------------TSPSR-------------- MCF2L_HUMAN MCF2L_HUMAN TS---------------------TSPSRGNSRNIKKLEERKTDPLSLEGYVSS-APLTKP A8MU87_HUMAN A8MU87_HUMAN TS---------------------TSPSRGNSRNIKKLEERKTDPLSLEGYVSS-APLTKP B7ZBJ8_HUMAN B7ZBJ8_HUMAN TS---------------------TSPSRGNSRNIKKLEERKTDPLSLEGYVSS-APLTKP B8A4Q9_DANRE B8A4Q9_DANRE ------------------------------------------------------------ Q4RY59_TETNG Q4RY59_TETNG SS------------------GSPSPFRSNVQKNQKKPEEKKLESNT----ISEVNSLASP Q4SVF8_TETNG Q4SVF8_TETNG ------------------------------------APLVRVPGQC------------GP Q4RP67_TETNG Q4RP67_TETNG QQ--------------------------RVSVSSEDTESGRSSP----------DPQAQS Q7ZZ90_DANRE Q7ZZ90_DANRE ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

MF2L2_HUMAN MF2L2_HUMAN SSMD---------------------------------------TFEDCEGAEDMEKESSA A2AEU1_MOUSE A2AEU1_MOUSE TEAG-------------------------------AEVEQAGALIKVREAAVLAQAEASS Q8BLE2_MOUSE Q8BLE2_MOUSE TEAG-------------------------------AEVEQAGALIKVREAAVLAQAEASS Q99N72_MOUSE Q99N72_MOUSE TEAG-------------------------------AEVEQAGALIKVREAAVLAQAEASS Q7TNJ5_MOUSE Q7TNJ5_MOUSE TEAG-------------------------------AEVEQAGALIKVREAAVLAQAEASS Q8C067_MOUSE Q8C067_MOUSE TEAG-------------------------------AEVEQAGALIKVREAAVLAQAEASS A2AET8_MOUSE A2AET8_MOUSE TEAG-------------------------------AEVEQAGALIKVREAAVLAQAEASS B7Z3Y5_HUMAN B7Z3Y5_HUMAN ---------------------------------------------DLCRR---------- Q5JYJ2_HUMAN Q5JYJ2_HUMAN ------------------------------------------------------------ B7Z3Z2_HUMAN B7Z3Z2_HUMAN ------------------------------------------------------------ B2R9S6_HUMAN B2R9S6_HUMAN ------------------------------------ELEHTSTVVEVCEAIASVQAEANT B7Z869_HUMAN B7Z869_HUMAN ------------------------------------ELEHTSTVVEVCEAIASVQAEANT B7ZAV1_HUMAN B7ZAV1_HUMAN ------------------------------------ELEHTSTVVEVCEAIASVQAEANT Q5JYJ7_HUMAN Q5JYJ7_HUMAN ------------------------------------ELEHTSTVVEVCEAIASVQAEANT Q5JYJ5_HUMAN Q5JYJ5_HUMAN ------------------------------------ELEHTSTVVEVCEAIASVQAEANT Q5JYJ6_HUMAN Q5JYJ6_HUMAN ------------------------------------ELEHTSTVVEVCEAIASVQAEANT Q5JYJ3_HUMAN Q5JYJ3_HUMAN ------------------------------------ELEHTSTVVEVCEAIASVQAEANT MCF2_HUMAN MCF2_HUMAN ------------------------------------ELEHTSTVVEVCEAIASVQAEANT Q4S0P7_TETNG Q4S0P7_TETNG TDAG----------------------------------PPPLTLSRPQWCSTSSVSQTKQ B8A4Q6_DANRE B8A4Q6_DANRE NDKLKDETVVSPNTERAAVAKKRFTLQGFSNLK--SQKGSSPPSPDHKTKRQSDPTPFGF MCF2L_RAT MCF2L_RAT PEKG-------------------------------------------------------- Q3UHQ9_MOUSE Q3UHQ9_MOUSE PEKGKDDAVPSSTSESSALSRKRFTLQGLANLKGQKASPTSPDKKAKRHEVKSDPTPFGL Q6PDM6_MOUSE Q6PDM6_MOUSE PEKGKDDAVPSSTSESSALSRKRFTLQGLANLKGQKASPTSPDKKAKRHEVKSDPTPFGL Q8C7Z1_MOUSE Q8C7Z1_MOUSE ------------------------------------------------------------ Q80U26_MOUSE Q80U26_MOUSE PEKG-------------------------------KASPTSPDKKAKRHEVKSDPTPFGL MCF2L_MOUSE MCF2L_MOUSE PEKG-------------------------------------------------------- Q003U3_MOUSE Q003U3_MOUSE PEKG-------------------------------------------------------- B5SNI0_OTOGA B5SNI0_OTOGA PEKGRDDVVTSSTSESSALSRKRFTLQGLANI---KASPTSPDKKAKRHEVKSDPTPFGL B3KT13_HUMAN B3KT13_HUMAN ------------------------------------------------------------ A9X169_PAPAN A9X169_PAPAN ------------------------------------------------------------ B1MTD7_CALMO B1MTD7_CALMO PEKG-------------------------------KASPTSPDKKAKRHGVKSDPTPFGV Q5REI0_PONAB Q5REI0_PONAB ------------------------------------------------------------ B4DHD6_HUMAN B4DHD6_HUMAN PEKG-------------------------------------------------------- B4DIL6_HUMAN B4DIL6_HUMAN PEKG-------------------------------------------------------- B7Z9K4_HUMAN B7Z9K4_HUMAN ------------------------------------------------------------ MCF2L_HUMAN MCF2L_HUMAN PEKG-------------------------------------------------------- A8MU87_HUMAN A8MU87_HUMAN PEKG-------------------------------KASPTSPDKKAKRHEVKSDPTPFGV B7ZBJ8_HUMAN B7ZBJ8_HUMAN PEKG-------------------------------KASPTSPDKKAKRHEVKSDPTPFGV B8A4Q9_DANRE B8A4Q9_DANRE ------------------------------------------------------------ Q4RY59_TETNG Q4RY59_TETNG KHRGLQQSQESKRLEQGVSVGGSFRGEQRVLQQRGPRQLRHRGRSSEEAGEPEPRSSSPA Q4SVF8_TETNG Q4SVF8_TETNG RRRG--------