Alignment of the gene Family HBG067993 of HOVERGEN

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Threshold: 50% 80% 100%
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Isoforms are ON
Q4RIS0_TETNG Q4RIS0_TETNG GLPALEFSDCYLDSPQFRDRLKSHELELDKTNKFIKELIKDGKALIQALKCFYEANANSP RHG26_XENLA RHG26_XENLA GLPPLEFSDCYLDSPQFRERLKSHETELDKTNKFIKELIKDGKSLVAAHK---------- RHG26_XENTR RHG26_XENTR GLPPLEFSDCYLDSPQFRERLKSHEIELDKTNKFIKELIKDGKSLVAAHK---------- RHG26_CHICK RHG26_CHICK GLPALEFSECCLDSPQFRERLRSHEAELEKTNKFIKELIKDGKSLIAALK---------- B7NZB3_RABIT B7NZB3_RABIT GLPALEFSDCCLDSPHFRETLKSHEAELDKTNKFIKELIKDGKSLISALK---------- B9EJ96_MOUSE B9EJ96_MOUSE GLPALEFSDCCLDSPHFRETLKSHEAELDKTNKFIKELIKDGKSLISALK---------- RHG26_MOUSE RHG26_MOUSE GLPALEFSDCCLDSPHFRETLKSHEAELDKTNKFIKELIKDGKSLISALK---------- Q5D035_HUMAN Q5D035_HUMAN GLPALEFSDCCLDSPHFRETLKSHEAELDKTNKFIKELIKDGKSLISALK---------- RHG26_HUMAN RHG26_HUMAN GLPALEFSDCCLDSPHFRETLKSHEAELDKTNKFIKELIKDGKSLISALK---------- Q1JPR9_DANRE Q1JPR9_DANRE GLHPLEFSECYLDSPAFRDKIKAHEAELEKTGRFIKELYKDGKNLINATK---------- Q4RKL2_TETNG Q4RKL2_TETNG ---------------------------------MFQRWLKKQAML--------------- Q2TAT2_XENLA Q2TAT2_XENLA GLQPLEFSDCYLDSPWLRERIRAHEAELDRTNRFIKDLLKDGKNLIAATK---------- Q6DEE5_XENLA Q6DEE5_XENLA GLQPLEFSDCYLDSPWLRERIRAHEAELDRTNRFIKDLLKDGKNLIAATK---------- RHG10_MOUSE RHG10_MOUSE GLQPLEFSDCYLDSPWFRERIRAHEAELERTNKFIKELIKDGKNLISATK---------- RHG10_BOVIN RHG10_BOVIN GLQPLEFSDCYLDSPWFRERIRAHEAELERTNKFIKELIKDGKNLIAATK---------- B3KVP5_HUMAN B3KVP5_HUMAN ------------------------------------------------------------ B4E2W2_HUMAN B4E2W2_HUMAN ------------------------------------------------------------ Q86T21_HUMAN Q86T21_HUMAN ------------------------------------------------------------ RHG10_HUMAN RHG10_HUMAN GLQPLEFSDCYLDSPWFRERIRAHEAELERTNKFIKELIKDGKNLIAATK---------- Q3KQX3_HUMAN Q3KQX3_HUMAN ------------------------------------------------------------ Q8ND72_HUMAN Q8ND72_HUMAN ------------------------------------------------------------ Q6IA27_HUMAN Q6IA27_HUMAN ------------------------------------------------------------ Q9H7G7_HUMAN Q9H7G7_HUMAN ------------------------------------------------------------ A2CEG8_DANRE A2CEG8_DANRE VHPALEFSDCYSDSPDFRERLKCYENELEKTNKFLKDVIKDGNNVINTFK---------- B1AV63_MOUSE B1AV63_MOUSE GHPPLEFSDCYLDSPDFRQRLKYYEEELERTNKFIKDVIKDGSALISAMR---------- OPHN1_MOUSE OPHN1_MOUSE GHPPLEFSDCYLDSPDFRQRLKYYEEELERTNKFIKDVIKDGSALISAMR---------- Q8C4C7_MOUSE Q8C4C7_MOUSE GHPPLEFSDCYLDSPDFRQRLKYYEEELERTNKFIKDVIKDGSALISAMR---------- Q6R7Z1_CAVPO Q6R7Z1_CAVPO GHPPLEFSDCYLDSPDFRERLKCYEQELERTNKFIKDVIKDGNALISAMR---------- B4DIT2_HUMAN B4DIT2_HUMAN GHPPLEFSDCYLDSPDFRERLKCYEQELERTNKFIKDIIKDGNALISAMR---------- B9EIP8_HUMAN B9EIP8_HUMAN GHPPLEFSDCYLDSPDFRERLKCYEQELERTNKFIKDIIKDGNALISAMR---------- OPHN1_PANTR OPHN1_PANTR GHPPLEFSDCYLDSPDFRERLKCYEQELERTNKFIKDVIKDGNALISAMR---------- OPHN1_PONPY OPHN1_PONPY GHPPLEFSDCYLDSPDFRERLKCYEQELERTNKFIKDVIKDGNALISAMR---------- OPHN1_HUMAN OPHN1_HUMAN GHPPLEFSDCYLDSPDFRERLKCYEQELERTNKFIKDVIKDGNALISAMR---------- Q0P4U1_XENTR Q0P4U1_XENTR GHSPLEFSDCYLDSPIFRESLKGYEQELERTNKFIKDVIKDGNALISAIK---------- Q6PCK6_XENLA Q6PCK6_XENLA GHPPLEFSECYLDSPVFRESLKGYEQELERTNKFIKDVIKDGNALISAIK---------- Q4RFN2_TETNG Q4RFN2_TETNG -----------------------------MTMRYV------------------------- Q4SFS4_TETNG Q4SFS4_TETNG GLPTLEFSDSFLDSPEFRERLQCHEIELERTNRFIKDLIKDGNMLVSALK---------- RH10L_DANRE RH10L_DANRE GLPALEFSDSFLDSPDFRERLKCHEIELDRTNKFIKELIKDGNMLISALK---------- B2RQE8_MOUSE B2RQE8_MOUSE GLPTLEFSDSYLDSPDFRERLQCHEIELERTNKFIKELLKDGSLLIGALR---------- Q0V8I4_BOVIN Q0V8I4_BOVIN ------------------------------------------------------------ RH10L_HUMAN RH10L_HUMAN GLPTLEFSDSYLDSPDFRERLQCHEIELERTNKFIKELIKDGSLLIGALR---------- YK021_HUMAN YK021_HUMAN ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

Q4RIS0_TETNG Q4RIS0_TETNG SRWDESRLMLERRGGLRPSSGLWIEAWRYRRAVLVDPLTGLSTAKRKFAESLNEFKFQCI RHG26_XENLA RHG26_XENLA ---------------------------------------SLSFAKRKFAGSLNEFKFRCI RHG26_XENTR RHG26_XENTR ---------------------------------------NLSCAKRKFAGSLNEFKFRCI RHG26_CHICK RHG26_CHICK ---------------------------------------NLSSAKRKFADSLNEFKFRCI B7NZB3_RABIT B7NZB3_RABIT ---------------------------------------NLSTAKRKFADSLNEFKFQCI B9EJ96_MOUSE B9EJ96_MOUSE ---------------------------------------NLSSAKRKFADSLNEFKFQCI RHG26_MOUSE RHG26_MOUSE ---------------------------------------NLSSAKRKFADSLNEFKFQCI Q5D035_HUMAN Q5D035_HUMAN ---------------------------------------NLSSAKRKFADSLNEFKFQCI RHG26_HUMAN RHG26_HUMAN ---------------------------------------NLSSAKRKFADSLNEFKFQCI Q1JPR9_DANRE Q1JPR9_DANRE ---------------------------------------QLSLAQKKFAQCLGEFKFEYI Q4RKL2_TETNG Q4RKL2_TETNG ---------------------------------------ELGMAQRKFAHCLGEFQFEYI Q2TAT2_XENLA Q2TAT2_XENLA ---------------------------------------SLSAAQRKFAHSLRDFKFEFI Q6DEE5_XENLA Q6DEE5_XENLA ---------------------------------------SLSTAQRKFAHSLRDFKFEFI RHG10_MOUSE RHG10_MOUSE ---------------------------------------SLSAAQRKFAHSLRDFKFEFI RHG10_BOVIN RHG10_BOVIN ---------------------------------------TLSAAQRKFAHSLRDFKFEFI B3KVP5_HUMAN B3KVP5_HUMAN ------------------------------------------------------------ B4E2W2_HUMAN B4E2W2_HUMAN ------------------------------------------------------------ Q86T21_HUMAN Q86T21_HUMAN ------------------------------------------------------------ RHG10_HUMAN RHG10_HUMAN ---------------------------------------SLSVAQRKFAHSLRDFKFEFI Q3KQX3_HUMAN Q3KQX3_HUMAN ------------------------------------------------------------ Q8ND72_HUMAN Q8ND72_HUMAN ------------------------------------------------------------ Q6IA27_HUMAN Q6IA27_HUMAN ------------------------------------------------------------ Q9H7G7_HUMAN Q9H7G7_HUMAN ------------------------------------------------------------ A2CEG8_DANRE A2CEG8_DANRE ---------------------------------------EYSLAVQKFSQTLQSFQFDFI B1AV63_MOUSE B1AV63_MOUSE ---------------------------------------NYSSAVQKFSQTLQSFQFDFI OPHN1_MOUSE OPHN1_MOUSE ---------------------------------------NYSSAVQKFSQTLQSFQFDFI Q8C4C7_MOUSE Q8C4C7_MOUSE ---------------------------------------NYSSAVQKFSQTLQSFQFDFI Q6R7Z1_CAVPO Q6R7Z1_CAVPO ---------------------------------------NYSSAVQKFSQTLQSFQFDFI B4DIT2_HUMAN B4DIT2_HUMAN ---------------------------------------NYSSAVQKFSQTLQSFQFDFI B9EIP8_HUMAN B9EIP8_HUMAN ---------------------------------------NYSSAVQKFSQTLQSFQFDFI OPHN1_PANTR OPHN1_PANTR ---------------------------------------NYSSAVQKFSQTLQSFQFDFI OPHN1_PONPY OPHN1_PONPY ---------------------------------------NYSSAVQKFSQTLQSFQFDFI OPHN1_HUMAN OPHN1_HUMAN ---------------------------------------NYSSAVQKFSQTLQSFQFDFI Q0P4U1_XENTR Q0P4U1_XENTR ---------------------------------------GYSSAVQKFSQTLQSYQFDFI Q6PCK6_XENLA Q6PCK6_XENLA ---------------------------------------GYSGAVQKFSQTLQSFQFDFI Q4RFN2_TETNG Q4RFN2_TETNG ------------------------------------------------------------ Q4SFS4_TETNG Q4SFS4_TETNG ---------------------------------------SLSVAVQRFSQSLQDFQFECI RH10L_DANRE RH10L_DANRE ---------------------------------------SLSAAVQKFSQSLQDFQFECI B2RQE8_MOUSE B2RQE8_MOUSE ---------------------------------------NLSMAVQKFSQSLQDFQFECI Q0V8I4_BOVIN Q0V8I4_BOVIN ------------------------------------------------------------ RH10L_HUMAN RH10L_HUMAN ---------------------------------------NLSMAVQKFSQSLQDFQFECI YK021_HUMAN YK021_HUMAN ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

Q4RIS0_TETNG Q4RIS0_TETNG GDAETDDEICIAKSLQEFAAVLQNLEDERTRMIENANDVLIMPLERFRKEQISAAKEAKK RHG26_XENLA RHG26_XENLA GDAETDDEICIARSLQEFAAVLGNLEDERIRMIDNAGEVLITPLEKFRKEQISAAKEVKK RHG26_XENTR RHG26_XENTR GDAETDDEICIARSLQEFAAVLGNLEDERIRMIDNSGEVLISPLEKFRKEQVGAAKEVKK RHG26_CHICK RHG26_CHICK GDAETDDEICIAKSLQEFATVLRNLEDERMRMIENASEVLITPLEKFRKEQIGAAKDAKK B7NZB3_RABIT B7NZB3_RABIT GDAETDDEMCIARSLQEFATVLRNLEDERIRMIENASEVLITPLEKFRKEQIGAAKEAKK B9EJ96_MOUSE B9EJ96_MOUSE GDAETDDEMCIARSLQEFAAVLRNLEDERSRMIENASEVLITPLEKFRKEQIGAAREAKK RHG26_MOUSE RHG26_MOUSE GDAETDDEMCIARSLQEFAAVLRNLEDERSRMIENASEVLITPLEKFRKEQIGAAREAKK Q5D035_HUMAN Q5D035_HUMAN GDAETDDEMCIARSLQEFATVLRNLEDERIRMIENASEVLITPLEKFRKEQIGAAKEAKK RHG26_HUMAN RHG26_HUMAN GDAETDDEMCIARSLQEFATVLRNLEDERIRMIENASEVLITPLEKFRKEQIGAAKEAKK Q1JPR9_DANRE Q1JPR9_DANRE GDAKTDDEKCIDESLQEFSLFLRNLEEQRDLMMRNITETLMKPLENFRKEHLGSAKAERK Q4RKL2_TETNG Q4RKL2_TETNG GDAKTDDEKCIDESLQEFSSFLKNLEDQRELMMRNITETLMKPLEKFRKEHLGTIRTEKK Q2TAT2_XENLA Q2TAT2_XENLA GDAETDDERCIDASLQEFSTFLQNLEEQREIMALNVNETLVKPLERFRKEQLGGVKELKK Q6DEE5_XENLA Q6DEE5_XENLA GDAETDDERCIDASLQEFSTFLQNLEEQREIMALNVNEALVKPLERFRKEQLGAVKELKK RHG10_MOUSE RHG10_MOUSE GDAETDDERCIDASLREFSNFLKNLEEQREIMALSVTETLIKPLEKFRKEQLGAVKEEKK RHG10_BOVIN RHG10_BOVIN GDAETDDERCIDASLREFSNFLKNLEEQREIMALSVTETLIKPLEKFRKEQLGAVKEEKK B3KVP5_HUMAN B3KVP5_HUMAN ------------------------------------------------------------ B4E2W2_HUMAN B4E2W2_HUMAN ------------------------------------------------------------ Q86T21_HUMAN Q86T21_HUMAN ------------------------------------------------------------ RHG10_HUMAN RHG10_HUMAN GDAVTDDERCIDASLREFSNFLKNLEEQREIMALSVTETLIKPLEKFRKEQLGAVKEEKK Q3KQX3_HUMAN Q3KQX3_HUMAN ------------------------------------------------------------ Q8ND72_HUMAN Q8ND72_HUMAN ------------------------------------------------------------ Q6IA27_HUMAN Q6IA27_HUMAN ------------------------------------------------------------ Q9H7G7_HUMAN Q9H7G7_HUMAN ------------------------------------------------------------ A2CEG8_DANRE A2CEG8_DANRE GDTLTDDEMNIAESFREFAGLLQDVEEARMMLVQNASDLLIKPLEKFRKEQIGVTKERRK B1AV63_MOUSE B1AV63_MOUSE GDTLTDDEINIAESFKEFAELLNEVENERMMMVQNASDLLIKPLETFRKEQIGFTKERKK OPHN1_MOUSE OPHN1_MOUSE GDTLTDDEINIAESFKEFAELLNEVENERMMMVQNASDLLIKPLETFRKEQIGFTKERKK Q8C4C7_MOUSE Q8C4C7_MOUSE GDTLTDDEINIAESFKEFAELLNEVENERMMMVQNASDLLIKPLETFRKEQIGFTKERKK Q6R7Z1_CAVPO Q6R7Z1_CAVPO GDTLTDDEINIAESFKEFAELLNEVENERMMMVHNASDLLIKPLENFRKEQIGFTKERKK B4DIT2_HUMAN B4DIT2_HUMAN GDTLTDDEINIAESFKEFAELLNEVENERMMMVHNASDLLIKPLENFRKEQIGFTKERKK B9EIP8_HUMAN B9EIP8_HUMAN GDTLTDDEINIAESFKEFAELLNEVENERMMMVHNASDLLIKPLENFRKEQIGFTKERKK OPHN1_PANTR OPHN1_PANTR GDTLTDDEINIAESFKEFAELLNEVENERMMMVHNASDLLIKPLENFRKEQIGFTKERKK OPHN1_PONPY OPHN1_PONPY GDTLTDDEINIAESFKEFAELLNEVENERMMMVHNASDLLIKPLENFRKEQIGFTKERKK OPHN1_HUMAN OPHN1_HUMAN GDTLTDDEINIAESFKEFAELLNEVENERMMMVHNASDLLIKPLENFRKEQIGFTKERKK Q0P4U1_XENTR Q0P4U1_XENTR GDTMTDDEINIAESFKEFADLLQEVENERMMMLQNADDLLIKPLESFRKDQIGLTKERKK Q6PCK6_XENLA Q6PCK6_XENLA GDTMTDDEINIAESFKEFADLLQEVETERMMMLQNADDLLIKPLENFRKDQIGLTKERKK Q4RFN2_TETNG Q4RFN2_TETNG -----------------------------FHLIQNADDVLITPLEKFRKEQIGAAKEGKK Q4SFS4_TETNG Q4SFS4_TETNG GDAETDDEISIAQSLKEFSQLLSTVEEERKRLIQNADDVLISPLERFRKEQIGAVKEGKK RH10L_DANRE RH10L_DANRE GDAETDDEINIAQSFKEFSQLLNTVEEERRRLIQNADDVLITPLEKFRKEQIGAAKEGKK B2RQE8_MOUSE B2RQE8_MOUSE GDAETDDEISIAQSLKEFARLLIAVEEERRRLIQNANDVLIAPLEKFRKEQIGAAK---- Q0V8I4_BOVIN Q0V8I4_BOVIN ------------------------------------------------------------ RH10L_HUMAN RH10L_HUMAN GDAETDDEISIAQSLKEFARLLIAVEEERRRLIQNANDVLIAPLEKFRKEQIGAAKDGKK YK021_HUMAN YK021_HUMAN ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

Q4RIS0_TETNG Q4RIS0_TETNG KYDKETEKYCAVLEKHLSLSARKKESHLHEADSQVD-----SVRQHFYEVSLEYVFKVQE RHG26_XENLA RHG26_XENLA KYDKETEKYCGMLEKHMNLSSKKKEVLLHEADVQLD-----QMRQHFYEVSLEYVLKVHE RHG26_XENTR RHG26_XENTR KYDKESEKYCAMLEKHMNLSSKKKEVLLHEADVQLD-----QMRQHFYEVSLEYVLKVHE RHG26_CHICK RHG26_CHICK KYDKETEKYCGVLEKHLNLSSKKKESQLQEADSQVD-----LVRQHFYEVSLEYVFKVQE B7NZB3_RABIT B7NZB3_RABIT KYDKETEKYCGVLEKHLNLSSKKKESQLQEADSQVD-----LVRQHFYEVSLEYVFKVQE B9EJ96_MOUSE B9EJ96_MOUSE KYDKETEKYCGTLEKHLNLSSKKKESQLQEADSQVD-----LVRQHFYEVSLEYVFKVQE RHG26_MOUSE RHG26_MOUSE KYDKETEKYCGTLEKHLNLSSKKKESQLQEADSQVD-----LVRQHFYEVSLEYVFKVQE Q5D035_HUMAN Q5D035_HUMAN KYDKETEKYCGILEKHLNLSSKKKESQLQEADSQVD-----LVRQHFYEVSLEYVFKVQE RHG26_HUMAN RHG26_HUMAN KYDKETEKYCGILEKHLNLSSKKKESQLQEADSQVD-----LVRQHFYEVSLEYVFKVQE Q1JPR9_DANRE Q1JPR9_DANRE KYEKETEKYYSSLEKLLNMSAKKKEPQLQEADVSVE-----LMRQHFQETSLEYVCKLQE Q4RKL2_TETNG Q4RKL2_TETNG HYEKETEKYYSSLEKLLNLSAKKKEPQLQEADSQVE-----IMRKHFQEESLDYVCKLQE Q2TAT2_XENLA Q2TAT2_XENLA KFDKETEKNYSLLDKHLSLSAKKKEPHLQEADVQVE-----QNRQHFYQLSLDYVCKLQE Q6DEE5_XENLA Q6DEE5_XENLA KFDKDTEKNYSVLDKHLSLSAKKKEPQLQEADVQVE-----QNRQHFYQLSLEYVCKLQE RHG10_MOUSE RHG10_MOUSE KFDKETEKNYSLIDKHLTLSARKKDSHLQEADLQVE-----QNRQHFYELSLEYVCKLQE RHG10_BOVIN RHG10_BOVIN KFDKETERNYSLIDKHLNLSAKKKDSHLQEADIQVE-----QNRQHFYELSLEYVCKLQE B3KVP5_HUMAN B3KVP5_HUMAN ------------------------------------------------------------ B4E2W2_HUMAN B4E2W2_HUMAN ------------------------------------------------------------ Q86T21_HUMAN Q86T21_HUMAN ------------------------------------------------------------ RHG10_HUMAN RHG10_HUMAN KFDKETEKNYSLIDKHLNLSAKKKDSHLQEADIQVE-----QNRQHFYELSLEYVCKLQE Q3KQX3_HUMAN Q3KQX3_HUMAN ------------------------------------------------------------ Q8ND72_HUMAN Q8ND72_HUMAN ------------------------------------------------------------ Q6IA27_HUMAN Q6IA27_HUMAN ------------------------------------------------------------ Q9H7G7_HUMAN Q9H7G7_HUMAN ------------------------------------------------------------ A2CEG8_DANRE A2CEG8_DANRE KFEKESEKYYSQLDKHVNLSSKKKETQLQEADEQLD-----KERQAFYESSVEYVYQIQQ B1AV63_MOUSE B1AV63_MOUSE KFEKDGERFYSLLDRHLHLSSKKKESQLLEADLQVD-----KERHNFFESSLDYVYQIQE OPHN1_MOUSE OPHN1_MOUSE KFEKDGERFYSLLDRHLHLSSKKKESQLLEADLQVD-----KERHNFFESSLDYVYQIQE Q8C4C7_MOUSE Q8C4C7_MOUSE KFEKDGERFYSLLDRHLHLSSKKKESQLLEADLQVD-----KERHNFFESSLDYVYQIQE Q6R7Z1_CAVPO Q6R7Z1_CAVPO KFEKDGERFYSLLDRHLHLSSKKKESQLQEADLPVD-----KERHNFFESSLDYVYQIQE B4DIT2_HUMAN B4DIT2_HUMAN KFEKDGERFYSLLDRHLHLSSKKKESQLQEADLQVD-----KERHNFFESSLDYVYQIQE B9EIP8_HUMAN B9EIP8_HUMAN KFEKDGERFYSLLDRHLHLSSKKKESQLQEADLQVD-----KERHNFFESSLDYVYQIQE OPHN1_PANTR OPHN1_PANTR KFEKDGERFYSLLDRHLHLSSKKKESQLQEADLQVD-----KERHNFFESSLDYVYQIQE OPHN1_PONPY OPHN1_PONPY KFEKDGERFYSLLDRHLHLSSKKKESQLQEADLQVD-----KERHNFFESSLDYVYQIQE OPHN1_HUMAN OPHN1_HUMAN KFEKDGERFYSLLDRHLHLSSKKKESQLQEADLQVD-----KERHNFFESSLDYVYQIQE Q0P4U1_XENTR Q0P4U1_XENTR KFDKDGEKYYSLLDRHVNLSSKKKEVQLNEADQQVD-----REKQNFYESSLEYVYQIQE Q6PCK6_XENLA Q6PCK6_XENLA KFDKDSEKFYSLLDRHVNLSSKKKEVQLNEADQQVD-----REKQNFYESSLEYVYQIQE Q4RFN2_TETNG Q4RFN2_TETNG KFDKETEKYYSTLERHLNLSSRKKEAYLQEADMQID-----KERQLFYDASLEYVFKIQE Q4SFS4_TETNG Q4SFS4_TETNG QFDKETERYYSVLEKHLSLSSKKKDSHLQEVKLSRSVQLMFSDRQIFYDASLQYVFKIQE RH10L_DANRE RH10L_DANRE KFDKETEKYYTVLEKHLSLSSRKKESLLQEADTQIS-----KERQVFYDASLEYVFKIQE B2RQE8_MOUSE B2RQE8_MOUSE ------------------------------ADSQIG-----REHQNFYEASLEYVFKIQE Q0V8I4_BOVIN Q0V8I4_BOVIN ------------------------------------------------------------ RH10L_HUMAN RH10L_HUMAN KFDKESEKYYSILEKHLNLSAKKKESHLQEADTQID-----REHQNFYEASLEYVFKIQE YK021_HUMAN YK021_HUMAN ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

Q4RIS0_TETNG Q4RIS0_TETNG VQERKMFDFVEPLLAFLQGLFTYYHHGYELAKDFNHFKTELTISIQNTRNRFESTRSEVE RHG26_XENLA RHG26_XENLA VQERKMFEFVEPLLAFLQGLFTFYHHGYELAKDFSDFKTQLSISIQNTRDRFEGTRSEVE RHG26_XENTR RHG26_XENTR VQERKMFEFVEPLLAFLQGLFTFYHHGYELAKDFSDFKTQLSISIQNTRDRFEGTRSEVE RHG26_CHICK RHG26_CHICK VQERKMFEFVEPLLAFLQGLFTFYHHGYELAKDFSDFKTELTISIQNTRNRFEGTRSEVE B7NZB3_RABIT B7NZB3_RABIT VQERKMFEFVEPLLAFLQGLFTFYHHGYELAKDFGDFKTQLTISIQNTRNRFEGTRSEVE B9EJ96_MOUSE B9EJ96_MOUSE VQERKMFEFVEPLLAFLQGLFTFYHHGYELAKDFGDFKTQLTISIQNTRNRFEGTRSEVE RHG26_MOUSE RHG26_MOUSE VQERKMFEFVEPLLAFLQGLFTFYHHGYELAKDFGDFKTQLTISIQNTRNRFEGTRSEVE Q5D035_HUMAN Q5D035_HUMAN VQERKMFEFVEPLLAFLQGLFTFYHHGYELAKDFGDFKTQLTISIQNTRNRFEGTRSEVE RHG26_HUMAN RHG26_HUMAN VQERKMFEFVEPLLAFLQGLFTFYHHGYELAKDFGDFKTQLTISIQNTRNRFEGTRSEVE Q1JPR9_DANRE Q1JPR9_DANRE IQERKKFECVEPMLAFFQTVFTFYHQGYELAKDFDHYKKALQINIQNTRNRFEGTRSEVF Q4RKL2_TETNG Q4RKL2_TETNG IQERKKFECVEPMLAFFQTVFTFYHQGFELAKDFEHYKRALQINIQNTRSRFEATRSEVH Q2TAT2_XENLA Q2TAT2_XENLA IQERKKFEFVEPMLSFFQGIFTFYHQGYELANDFNHYKLDLQINIQNTRNLFDGTRSEVE Q6DEE5_XENLA Q6DEE5_XENLA IQERKKFEFVEPMLSFFQGIFTFYHQGYELAKDFNHYKLELQINIQNTRNRFEGTRSEVE RHG10_MOUSE RHG10_MOUSE IQERKKFEFVEPMLSFFQGMFTFYHQGHELSKDFNHYKMELQINIQNTRNRFEGTRSEVE RHG10_BOVIN RHG10_BOVIN IQERKKFEFVEPMLSFFQGMFTFYHQGHELAKDFNHYKMELQINIQNTRNRFEGTRSEVE B3KVP5_HUMAN B3KVP5_HUMAN ------------------------------------------------------------ B4E2W2_HUMAN B4E2W2_HUMAN ------------------------------------------------------------ Q86T21_HUMAN Q86T21_HUMAN --------MIKVLTIFF------------------------------------------- RHG10_HUMAN RHG10_HUMAN IQERKKFEFVEPMLSFFQGMFTFYHQGHELAKDFNHYKMELQINIQNTRNRFEGTRSEVE Q3KQX3_HUMAN Q3KQX3_HUMAN ------------------------------------------------------------ Q8ND72_HUMAN Q8ND72_HUMAN ------------------------------------------------------------ Q6IA27_HUMAN Q6IA27_HUMAN ------------------------------------------------------------ Q9H7G7_HUMAN Q9H7G7_HUMAN ------------------------------------------------------------ A2CEG8_DANRE A2CEG8_DANRE VQEKKKFDVVEPVLAFLQSILTLNNLTVEMTQDFLPYKQELQLSLQNTRNHFESTREEME B1AV63_MOUSE B1AV63_MOUSE VQESKKFNIVEPVLAFLHSLFISNSLTVELTQDFLPYKQQLQLSLQNTRNHFSSTREEME OPHN1_MOUSE OPHN1_MOUSE VQESKKFNIVEPVLAFLHSLFISNSLTVELTQDFLPYKQQLQLSLQNTRNHFSSTREEME Q8C4C7_MOUSE Q8C4C7_MOUSE VQESKKFNIVEPVLAFLHSLFISNSLTVELTQDFLPYKQQLQLSLQNTRNHFSSTREEME Q6R7Z1_CAVPO Q6R7Z1_CAVPO VQEPKKFNIVEPVLAFLHSLFISNSLTVELTQDFLPYKQQLQLSLQNTRNHFSSTREEME B4DIT2_HUMAN B4DIT2_HUMAN VQESKKFNIVEPVLAFLHSLFISNSLTVELTQDFLPYKQQLQLSLQNTRNHFSSTREEME B9EIP8_HUMAN B9EIP8_HUMAN VQESKKFNIVEPVLAFLHSLFISNSLTVELTQDFLPYKQQLQLSLQNTRNHFSSTREEME OPHN1_PANTR OPHN1_PANTR VQESKKFNIVEPVLAFLHSLFISNSLTVELTQDFLPYKQQLQLSLQNTRNHFSSTREEME OPHN1_PONPY OPHN1_PONPY VQESKKFNIVEPVLAFLHSLFISNSLTVELTQDFLPYKQQLQLSLQNTRNHFSSTREEME OPHN1_HUMAN OPHN1_HUMAN VQESKKFNIVEPVLAFLHSLFISNSLTVELTQDFLPYKQQLQLSLQNTRNHFSSTREEME Q0P4U1_XENTR Q0P4U1_XENTR VQESKKFCIVEPVLTFLHCLFTSNNLTFELTQDFLPYKQQLQLSLQNTRNHFSSTREELE Q6PCK6_XENLA Q6PCK6_XENLA VQESKKFCVVEPVLTFLHCLFTSNNLTFELSQDFLPYKQQLQLSLQNTRNHFSSTREELE Q4RFN2_TETNG Q4RFN2_TETNG VQEKKKFEFVEPLLAFLQGLFTFYHEGYELAHEFEPYKQQLQFNLQNTRNNFVSTKQEVE Q4SFS4_TETNG Q4SFS4_TETNG VQERKKFEFVEPLLAFLQGLFTFYHEGYELAREFEPYKRQLQFNLQNARNNFESTRAEVE RH10L_DANRE RH10L_DANRE VQERKKFEFVEPLLAFLQGLFTFYHEGYELAHEFEPYKQQLQFNLQNTRNNFESTRQEVE B2RQE8_MOUSE B2RQE8_MOUSE VQEKKKFEFVEPLLSFLQGLFTFYHEGYELAQEFAPYKQQLQFNLQNTRNNFESTRQEVE Q0V8I4_BOVIN Q0V8I4_BOVIN ------------------------------------------------------------ RH10L_HUMAN RH10L_HUMAN VQEKKKFEFVEPLLSFLQGLFTFYHEGYELAQEFAPYKQQLQFNLQNTRNNFESTRQEVE YK021_HUMAN YK021_HUMAN ------------------------------------------------------------ MATCH CONSENSUS ???????????????F????????????????????????????????????????????

Q4RIS0_TETNG Q4RIS0_TETNG SLMRKMKENPHEHKSVSHH-TMEGYLFVQEKR--SFVSTWVKYYCTYHREPKRVTMVLFD RHG26_XENLA RHG26_XENLA SLMKKMKENPHEHLALSPF-TMEGYLYVQEKR--HFGTSWVKHYCTYQRETKQMTMVPFD RHG26_XENTR RHG26_XENTR SLMKKMKENPHEHLALSPY-TMEGYLYVQEKR--HFGTSWVKHYCTYQRETKQMTMVPFD RHG26_CHICK RHG26_CHICK SLMKKMKENPHEHKNISPY-TMEGYLYVQEKR--HFGTSWVKHYCTYQRESKRITMVPFD B7NZB3_RABIT B7NZB3_RABIT SLMRKMKENPLEHKTISPY-TMEGYLYVQEKR--HFGTSWVKHYCTYQRDSKQISMVPFD B9EJ96_MOUSE B9EJ96_MOUSE SLMKKMKENPLEHKTISPY-TMEGYLYVQEKR--HFGTSWVKHYCTYQRDSKQITMVPFD RHG26_MOUSE RHG26_MOUSE SLMKKMKENPLEHKTISPY-TMEGYLYVQEKR--HFGTSWVKHYCTYQRDSKQITMVPFD Q5D035_HUMAN Q5D035_HUMAN SLMKKMKENPLEHKTISPY-TMEGYLYVQEKR--HFGTSWVKHYCTYQRDSKQITMVPFD RHG26_HUMAN RHG26_HUMAN SLMKKMKENPLEHKTISPY-TMEGYLYVQEKR--HFGTSWVKHYCTYQRDSKQITMVPFD Q1JPR9_DANRE Q1JPR9_DANRE ELMKRIKESPQDYRQTSPI-SSEGYLYVQEKRPPPFGSSWVKRYSTFVKEQKILHMKTFD Q4RKL2_TETNG Q4RKL2_TETNG ELMKRVKDAPQEYRQTSPI-----------SWPPPFGSSWVKRYCTFVKEQKILHMVTFD Q2TAT2_XENLA Q2TAT2_XENLA DLLRKIRRNPQEHKRASPF-TMEGYLYVQEKRPAPFGSSWVKHYCMYKKDSKSFTMFPYE Q6DEE5_XENLA Q6DEE5_XENLA ELLRKIRINPQDHKRASPF-TMEGYLYVQEKRPAPFGSSWVKHYCMYKKDSKSFTMFPYE RHG10_MOUSE RHG10_MOUSE ELMNKIRQNPKDQKRASQF-TAEGYLYVQEKRPAPFGSSWVKHYCMYRKTAKKFNMIPFE RHG10_BOVIN RHG10_BOVIN ELMNKIRQNPKDHKRASQF-TAEGYLYVQEKRPPPFGSSWVKHYCMYRKAAKKFTMIPFE B3KVP5_HUMAN B3KVP5_HUMAN ------------------------------------------------------------ B4E2W2_HUMAN B4E2W2_HUMAN ---------------------------------------------MYRKAAKKFNMIPFE Q86T21_HUMAN Q86T21_HUMAN ------------------------------------------------------------ RHG10_HUMAN RHG10_HUMAN ELMNKIRQNPKDHKRASQF-TAEGYLYVQEKRPAPFGSSWVKHYCMYRKAAKKFNMIPFE Q3KQX3_HUMAN Q3KQX3_HUMAN ------------------------------------------------------------ Q8ND72_HUMAN Q8ND72_HUMAN ------------------------------------------------------------ Q6IA27_HUMAN Q6IA27_HUMAN ------------------------------------------------------------ Q9H7G7_HUMAN Q9H7G7_HUMAN ------------------------------------------------------------ A2CEG8_DANRE A2CEG8_DANRE ELMKRMKGSAKISIRHGQPATMEGYLYVQEKW--ALGVTWVKNYCKYFKDNKLFIMVPME B1AV63_MOUSE B1AV63_MOUSE ELKKRMKEAPQTCKLPGQP-TIEGYLYTQEKW--ALGISWAKYYCRYEKETRMLTMIPME OPHN1_MOUSE OPHN1_MOUSE ELKKRMKEAPQTCKLPGQP-TIEGYLYTQEKW--ALGISWAKYYCRYEKETRMLTMIPME Q8C4C7_MOUSE Q8C4C7_MOUSE ELKKRMKEASQTCKLPGQP-TIEGYLYTQEKW--ALGISWAKYYCRYEKETRMLTMIPME Q6R7Z1_CAVPO Q6R7Z1_CAVPO ELKKRMKEAPQTCKLPGQP-TIEGYLYTQEKW--ALGISWVKYYCQYEKETKTLTMTPME B4DIT2_HUMAN B4DIT2_HUMAN ELKKRMKEAPQTCKLPGQP-TIEGYLYTQEKW--ALGISWVKYYCQYEKETKTLTMTPME B9EIP8_HUMAN B9EIP8_HUMAN ELKKRMKEAPQTCKLPGQP-TIEGYLYTQEKW--ALGISWVKYYCQYEKETKTLTMTPME OPHN1_PANTR OPHN1_PANTR ELKKRMKEAPQTCKLPGQP-TIEGYLYTQEKW--ALGISWVKYYCQYEKETKTLTMTPME OPHN1_PONPY OPHN1_PONPY ELKKRMKEAPQTCKLPGQP-TIEGYLYTQEKW--ALGISWVKYYCQYEKETKTLTMTPME OPHN1_HUMAN OPHN1_HUMAN ELKKRMKEAPQTCKLPGQP-TIEGYLYTQEKW--ALGISWVKYYCQYEKETKTLTMTPME Q0P4U1_XENTR Q0P4U1_XENTR DLKKRMTEAPMMCKLRGQS-TIEGYLYSQEKR--ALGITWVKHYCKYEKEGKVLSMMPLE Q6PCK6_XENLA Q6PCK6_XENLA DLKKRMTEAPMVCKLRGQS-TIEGYLYSQEKR--ALGITWVKYYCKYEKEGKVLSMMSVE Q4RFN2_TETNG Q4RFN2_TETNG KLMKRIRSADQDCKPPGQW-TMEGFLYVQEKR--PLGCTWTRHYCTYDKSSNTFTMSATE Q4SFS4_TETNG Q4SFS4_TETNG RLMKRIRSAEEDFKAPSSF-TMEGYLYIQEKR--PLGSVWTRYYCTYEKSSKMFTMSSTE RH10L_DANRE RH10L_DANRE NLMRRIRSAEQDFKAPGQW-TMEGFLYVQEKR--PLGCTWTRHYCTYEKGTKMFTMSNSE B2RQE8_MOUSE B2RQE8_MOUSE RLMQRMKSANQDYRPPSQW-TMEGYLYVQEKR--PLGFTWTKHYCTYDKGSKMFTMSVSD Q0V8I4_BOVIN Q0V8I4_BOVIN ------------------------------------------------------------ RH10L_HUMAN RH10L_HUMAN RLMQRMKSANQDYRPPSQW-TMEGYLYVQEKPLGPLGFTWIKHYCTYDKGSKTFTMSVSE YK021_HUMAN YK021_HUMAN ------------------------------------------------------------ MATCH CONSENSUS ???????????????????????????????????????????????????????M????

Q4RIS0_TETNG Q4RIS0_TETNG PKSGGKM----------------------------------GEEESFILKSCTRRKTDSI RHG26_XENLA RHG26_XENLA QKSGGKV----------------------------------GEEELVQLKSCIRRKTESI RHG26_XENTR RHG26_XENTR QKSGGKV----------------------------------GEEEIIHLKSCIRRKTESI RHG26_CHICK RHG26_CHICK QKSGGKG----------------------------------GEDEAVILKSCTRRKTDSI B7NZB3_RABIT B7NZB3_RABIT QKSGGKG----------------------------------GEDETITLKSCTRRKTDSI B9EJ96_MOUSE B9EJ96_MOUSE QKSGGKG----------------------------------GEDESVTLKSCTRRKTDSI RHG26_MOUSE RHG26_MOUSE QKSGGKG----------------------------------GEDESVTLKSCTRRKTDSI Q5D035_HUMAN Q5D035_HUMAN QKSGGKG----------------------------------GEDESVILKSCTRRKTDSI RHG26_HUMAN RHG26_HUMAN QKSGGKG----------------------------------GEDESVILKSCTRRKTDSI Q1JPR9_DANRE Q1JPR9_DANRE QRSGGKL----------------------------------GETESVTLKSCVRKTTDAL Q4RKL2_TETNG Q4RKL2_TETNG HRSGGKLVSGRRTHQTPGCFHLRRKNPMQIKHIIVAFHLFQGETESVTLKSCVRKTTDML Q2TAT2_XENLA Q2TAT2_XENLA HRSGGKI----------------------------------GDGDSFSLKSCIKRHTDTI Q6DEE5_XENLA Q6DEE5_XENLA HRSGGKI----------------------------------GEGDSFSLKSCTKRHTDTI RHG10_MOUSE RHG10_MOUSE HRSGGKL----------------------------------GDGEAFFLKECTKRHMDST RHG10_BOVIN RHG10_BOVIN HRSGGKL----------------------------------GDGEVFFLKECIRRHTDSI B3KVP5_HUMAN B3KVP5_HUMAN ------------------------------------------------------------ B4E2W2_HUMAN B4E2W2_HUMAN HRSGGKL----------------------------------GDGEVFFLKECTKRHTDSI Q86T21_HUMAN Q86T21_HUMAN ------------------------------------------------------------ RHG10_HUMAN RHG10_HUMAN HRSGGKL----------------------------------GDGEVFFLKECTKRHTDSI Q3KQX3_HUMAN Q3KQX3_HUMAN ------------------------------------------------------------ Q8ND72_HUMAN Q8ND72_HUMAN ------------------------------------------------------------ Q6IA27_HUMAN Q6IA27_HUMAN ------------------------------------------------------------ Q9H7G7_HUMAN Q9H7G7_HUMAN ------------------------------------------------------------ A2CEG8_DANRE A2CEG8_DANRE QKAGIKQ-----------------------------------TTAQLTLKSCIRRKTDST B1AV63_MOUSE B1AV63_MOUSE QKPGAKQ-----------------------------------GPVDLTLKYCVRRKTESI OPHN1_MOUSE OPHN1_MOUSE QKPGAKQ-----------------------------------GPVDLTLKYCVRRKTESI Q8C4C7_MOUSE Q8C4C7_MOUSE QKPGAKQ-----------------------------------GPVDLTLKYCVRRKTESI Q6R7Z1_CAVPO Q6R7Z1_CAVPO QKPGAKQ-----------------------------------GPLDLTLKYCVRRKTESI B4DIT2_HUMAN B4DIT2_HUMAN QKPGAKQ-----------------------------------GPLDLTLKYCVRRKTESI B9EIP8_HUMAN B9EIP8_HUMAN QKPGAKQ-----------------------------------GPLDLTLKYCVRRKTESI OPHN1_PANTR OPHN1_PANTR QKPGAKQ-----------------------------------GPLDLTLKYCVRRKTESI OPHN1_PONPY OPHN1_PONPY QKPGAKQ-----------------------------------GPLDLTLKYCVRRKTESI OPHN1_HUMAN OPHN1_HUMAN QKPGAKQ-----------------------------------GPLDLTLKYCVRRKTESI Q0P4U1_XENTR Q0P4U1_XENTR QKPGSRQ-----------------------------------GNQELTLKSCIRRKSDSI Q6PCK6_XENLA Q6PCK6_XENLA QKPGSKQ-----------------------------------GNQELTLKSCIRRKSDSI Q4RFN2_TETNG Q4RFN2_TETNG NKSAAKQNG-----------------------------LVLNQPEMFKLKSCIRRKTDSI Q4SFS4_TETNG Q4SFS4_TETNG SRAANRQNG-----------------------------VVNVTPEMFRLRSCVRRKRDSI RH10L_DANRE RH10L_DANRE LKTGGKQNG-----------------------------LIMSPPEMFKLKSCIRRRTDSI B2RQE8_MOUSE B2RQE8_MOUSE VKASGKMNG-----------------------------LVTGSPEMFKLKSCIRRKTDSI Q0V8I4_BOVIN Q0V8I4_BOVIN ------------------------------------------------------------ RH10L_HUMAN RH10L_HUMAN MKSSGKMNG-----------------------------LVTSSPEMFKLKSCIRRKTDSI YK021_HUMAN YK021_HUMAN ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????L??C????????

Q4RIS0_TETNG Q4RIS0_TETNG EKRFCFDVEAVDRPGV-ITMQALSEEDRRLWMEAMDGREPV---YNLNKDNQAEGM---- RHG26_XENLA RHG26_XENLA EKRFCFDVEGVDRPTV-LTMQALSEEDRKLWMEAMDGREPV---YNSNKDSQSEGT---- RHG26_XENTR RHG26_XENTR EKRFCFDVEGVDRPTV-LTMQALSEEDRKLWMEAMDGREPV---YNSNKDSQSEGT---- RHG26_CHICK RHG26_CHICK EKRFCFDVEAVDRPGV-ITMQALSEEDRRLWMEAMDGREPV---YNSNKDNQSEGT---- B7NZB3_RABIT B7NZB3_RABIT EKRFCFDVEAVDRPGV-ITMQALSEEDRRLWMEAMDGREPV---YNSNKDNQNEGT---- B9EJ96_MOUSE B9EJ96_MOUSE EKRFCFDVEAVDRPGV-ITMQALSEEDRRLWMEAMDGREPV---YNSNRDSQSEGT---- RHG26_MOUSE RHG26_MOUSE EKRFCFDVEAVDRPGV-ITMQALSEEDRRLWMEAMDGREPV---YNSNRDSQSEGT---- Q5D035_HUMAN Q5D035_HUMAN EKRFCFDVEAVDRPGV-ITMQALSEEDRRLWMEAMDGREPV---YNSNKDSQSEGT---- RHG26_HUMAN RHG26_HUMAN EKRFCFDVEAVDRPGV-ITMQALSEEDRRLWMEAMDGREPV---YNSNKDSQSEGT---- Q1JPR9_DANRE Q1JPR9_DANRE DRRFCLDIEITDRPGTVLTVQALSEDDHKFWMHAMGGKEPM---QCLNRTHSRERGID-- Q4RKL2_TETNG Q4RKL2_TETNG DRRFCLDLDITDRPGTVLTVQALSEDDHKFWMQAMGGKEPV---SWLCID---------- Q2TAT2_XENLA Q2TAT2_XENLA DRRFCFDIEASERPGVLTTMQSFSEDNRCLWMEVLDGKESRFLSLSRSVSRPEGG----- Q6DEE5_XENLA Q6DEE5_XENLA DRRFCFDIEASERPGVLTTMQSFSEDDRCLWMEVLDGKESRFLSLSRSVSRPEGG----- RHG10_MOUSE RHG10_MOUSE DRRFCFDIEAADRPGVPLTVQAFSEEERKQWLEALGGKEALFHTFNRAIVPRPEGG---- RHG10_BOVIN RHG10_BOVIN DRRFCFDVEAADRPGISLTMQAFSEEERKQWLEVLGGKEALFPSFNRAIIPRPEGS---- B3KVP5_HUMAN B3KVP5_HUMAN -------------------MQAFSEEERKQWLEALGGKEALSHSFNTAIIPRPEGN---- B4E2W2_HUMAN B4E2W2_HUMAN DRRFCFDIEAADRPGVSLTMRAFSEEERKQWLEALGGKEALSHSFNTAIIPRPEGN---- Q86T21_HUMAN Q86T21_HUMAN ------------------------------------------------------------ RHG10_HUMAN RHG10_HUMAN DRRFCFDIEAADRPGVSLTMQAFSEEERKQWLEALGGKEALSHSFNTAIIPRPEGN---- Q3KQX3_HUMAN Q3KQX3_HUMAN ------------------------------------------------------------ Q8ND72_HUMAN Q8ND72_HUMAN ------------------------------------------------------------ Q6IA27_HUMAN Q6IA27_HUMAN --MLCW------------------------------------------------------ Q9H7G7_HUMAN Q9H7G7_HUMAN --MLCW------------------------------------------------------ A2CEG8_DANRE A2CEG8_DANRE DKRFCFDIETSERGSP-VLLQAISEVNRKQWIEAMDGKEPI---YHSPIQKQAE------ B1AV63_MOUSE B1AV63_MOUSE DKRFCFDIETNERPGT-ITLQAPSEANRRLWMEAMDGKEPI---YHTPITKQEE------ OPHN1_MOUSE OPHN1_MOUSE DKRFCFDIETNERPGT-ITLQAPSEANRRLWMEAMDGKEPI---YHTPITKQEE------ Q8C4C7_MOUSE Q8C4C7_MOUSE DKRFCFDIETNERPGT-ITLQAPSEANRRLWMEAMDGKEPI---YHTPITKQEE------ Q6R7Z1_CAVPO Q6R7Z1_CAVPO DKRFCFDIETNERPGT-ITLQALSEANRRLWMEAMDGKEPI---YHSPITKQQE------ B4DIT2_HUMAN B4DIT2_HUMAN DKRFCFDIETNERPGT-ITLQALSEANRRLWMEAMDGKEPI---YHSPITKQQE------ B9EIP8_HUMAN B9EIP8_HUMAN DKRFCFDIETNERPGT-ITLQALSEANRRLWMEAMDGKEPI---YHSPITKQQE------ OPHN1_PANTR OPHN1_PANTR DKRFCFDIETNERPGT-ITLQALSEANRRLWMEAMDGKEPI---YHSPITKQQE------ OPHN1_PONPY OPHN1_PONPY DKRFCFDIETNERPGT-ITLQALSEANRRLWMEAMDGKEPI---YHSPITKQQE------ OPHN1_HUMAN OPHN1_HUMAN DKRFCFDIETNERPGT-ITLQALSEANRRLWMEAMDGKEPI---YHSPITKQQE------ Q0P4U1_XENTR Q0P4U1_XENTR DKRFCFDVETNERPGT-LTLQALSETNRRLWIEAMDGKEPI---YHSPITKRDE------ Q6PCK6_XENLA Q6PCK6_XENLA DKRFCFDVATNERPGT-LTLQALSETNRRLWIEAMDGKEPI---YHSPITKRDE------ Q4RFN2_TETNG Q4RFN2_TETNG DKRFCFDIEVVERHGV-MTLQALSESNRRLWLEAMDGKEPN---W--------------- Q4SFS4_TETNG Q4SFS4_TETNG DKRFCFDIEVVERHGV-ITLQALSEANRRLWMEAMDGKEPI---YTLPSLLSKKEE---- RH10L_DANRE RH10L_DANRE DKRFCFDIEVVERHGI-ITLQSLSESNRRLWMEAMDGKEPI---YTLPALLSKKEE---- B2RQE8_MOUSE B2RQE8_MOUSE DKRFCFDIEVVERHGI-ITLQAFSEANRKLWLEAMDGKEPI---YTLPAIISKKEE---- Q0V8I4_BOVIN Q0V8I4_BOVIN ------------------------------------------------------------ RH10L_HUMAN RH10L_HUMAN DKRFCFDIEVVERHGI-ITLQAFSEANRKLWLEAMDGKEPI---YTLPAIISKKEESKSF YK021_HUMAN YK021_HUMAN ------------------------------------------------------------ MATCH CONSENSUS ??RFC?D?????R???????Q??SE?????W?????G?E?????????????????????

Q4RIS0_TETNG Q4RIS0_TETNG AQLDVTGFNVMKKFIYAVETRGI----------------------------DEQGLYRIA RHG26_XENLA RHG26_XENLA AQLDNIGFSIIRKCIQAIETRGI----------------------------NEQGLYRIV RHG26_XENTR RHG26_XENTR AQLDNIGFSIIRKCIQAVETRGI----------------------------NEQGLYRIV RHG26_CHICK RHG26_CHICK AQLDSIGFSIIKKCIHAVETRGI----------------------------NEQGLYRIV B7NZB3_RABIT B7NZB3_RABIT AQLDSIGFSIIRKCIHAVETRGI----------------------------NEQGLYRIV B9EJ96_MOUSE B9EJ96_MOUSE AQLDSIGFSIIRKCIHAVETRGI----------------------------NEQGLYRIV RHG26_MOUSE RHG26_MOUSE AQLDSIGFSIIRKCIHAVETRGI----------------------------NEQGLYRIV Q5D035_HUMAN Q5D035_HUMAN AQLDSIGFSIIRKCIHAVETRGI----------------------------NEQGLYRIV RHG26_HUMAN RHG26_HUMAN AQLDSIGFSIIRKCIHAVETRGI----------------------------NEQGLYRIV Q1JPR9_DANRE Q1JPR9_DANRE AQLDDVGISFVKNSINAIEARGI----------------------------NDQGLYRVV Q4RKL2_TETNG Q4RKL2_TETNG AQMDDVGLDFVKNSISAIEKRGI----------------------------NDQGLYRVA Q2TAT2_XENLA Q2TAT2_XENLA ARLDKYGFAIVKNCIRAIETRGI----------------------------NDQGLYRVV Q6DEE5_XENLA Q6DEE5_XENLA ARLDKYGFAIVKNCIRAIETRGI----------------------------NEQGLYRVV RHG10_MOUSE RHG10_MOUSE AQLDKMGFTILRKCISAVETRGI----------------------------NDQGLYRVV RHG10_BOVIN RHG10_BOVIN AQLDKMGFTILRKCIRAVETRGI----------------------------NDQGLYRVV B3KVP5_HUMAN B3KVP5_HUMAN AQLDKMGFTIIRKCISAVETRGI----------------------------NDQGLYRVV B4E2W2_HUMAN B4E2W2_HUMAN AQLDKMGFTIIRKCISAVETRGI----------------------------NDQGLYRVV Q86T21_HUMAN Q86T21_HUMAN ------------------------------------------------------------ RHG10_HUMAN RHG10_HUMAN AQLDKMGFTIIRKCISAVETRGI----------------------------NDQGLYRVV Q3KQX3_HUMAN Q3KQX3_HUMAN ------------------------------------------------------------ Q8ND72_HUMAN Q8ND72_HUMAN ------------------------------------------------------------ Q6IA27_HUMAN Q6IA27_HUMAN ------------------------------------------------------------ Q9H7G7_HUMAN Q9H7G7_HUMAN ------------------------------------------------------------ A2CEG8_DANRE A2CEG8_DANRE MELNDLGFKFVRKCINFVETKGL----------------------------TQEGVYRTV B1AV63_MOUSE B1AV63_MOUSE MELNEVGFKFVRKCINFIETKGI----------------------------KTEGLYRTV OPHN1_MOUSE OPHN1_MOUSE MELNEVGFKFVRKCINFIETKGI----------------------------KTEGLYRTV Q8C4C7_MOUSE Q8C4C7_MOUSE MELNEVGFKFVRKCINFIETKGI----------------------------KTEGLYRTV Q6R7Z1_CAVPO Q6R7Z1_CAVPO MELNEGGFKFVRKCINIIETKGI----------------------------KTEGLYPTV B4DIT2_HUMAN B4DIT2_HUMAN MELNEVGFKFVRKCINIIETKGI----------------------------KTEGLYRTV B9EIP8_HUMAN B9EIP8_HUMAN MELNEVGFKFVRKCINIIETKGI----------------------------KTEGLYRTV OPHN1_PANTR OPHN1_PANTR MELNEVGFKFVRKCINIIETKGI----------------------------KTEGLYRTV OPHN1_PONPY OPHN1_PONPY MELNEVGFKFVRKCINIIETKGI----------------------------KTEGLYRTV OPHN1_HUMAN OPHN1_HUMAN MELNEVGFKFVRKCINIIETKGI----------------------------KTEGLYRTV Q0P4U1_XENTR Q0P4U1_XENTR MELNEVGFRFVRKCINAVEATGI----------------------------TSEGVYRTV Q6PCK6_XENLA Q6PCK6_XENLA MELNEVGFRFVRKCINAVEATGI----------------------------ASEGVYRTV Q4RFN2_TETNG Q4RFN2_TETNG -----------RGQLQSTEADDY------------------------------------- Q4SFS4_TETNG Q4SFS4_TETNG TFLNEAGLNFVKQCIKLIETRGISLNMSIRVKMLLCPVNFLLPSLFLCEGLTTPGLYRTG RH10L_DANRE RH10L_DANRE TFLNEAGFNFVRKCIESVEARGI----------------------------NTLGLYRIG B2RQE8_MOUSE B2RQE8_MOUSE MYLNEAGFNFVRKCIQAVEMRGI----------------------------TILGLYRIG Q0V8I4_BOVIN Q0V8I4_BOVIN ------------------------------------------------------------ RH10L_HUMAN RH10L_HUMAN LYLNEAGFNFVRKCIQAVETRGI----------------------------TILGLYRIG YK021_HUMAN YK021_HUMAN MYLNEAGFNFVRKCIQAVETRGI----------------------------TILGLYRIG MATCH CONSENSUS ??L???G???????I???E??GI???????????????????????????????G?YR??

Q4RIS0_TETNG Q4RIS0_TETNG GVNSRVQKLLSLAMDPKTCADVELE-NHEWEIKTITSAIKHYLRMLPAPLMTYQYQRSFI RHG26_XENLA RHG26_XENLA GVNSRVQKLLNILMDPKISPETETEIPSEWEIKTITSSLKTYLRMLPGPLMTYQFQRSFI RHG26_XENTR RHG26_XENTR GVNSRVQKLLNFLMDPKISPETETEIPSEWEIKTITSSLKTYLRMLPGPLMTYQFQRSFI RHG26_CHICK RHG26_CHICK GVNSRVQKLLSILMDPKTATETETEICAEWEIKTITSALKTYLRMLPGPLMMYQFQRSFI B7NZB3_RABIT B7NZB3_RABIT GVNSRVQKLLSVLMDPKTAAETETDICAEWEIKTITSALKTYLRMLPGPLMMYQFQRSFI B9EJ96_MOUSE B9EJ96_MOUSE GVNSRVQKLLSVLMDPKAASETETDICAEWEIKTVTSALKTYLRMLPGPLMMYQFQRSFI RHG26_MOUSE RHG26_MOUSE GVNSRVQKLLSVLMDPKAASETETDICAEWEIKTVTSALKTYLRMLPGPLMMYQFQRSFI Q5D035_HUMAN Q5D035_HUMAN GVNSRVQKLLSVLMDPKTASETETDICAEWEIKTITSALKTYLRMLPGPLMMYQFQRSFI RHG26_HUMAN RHG26_HUMAN GVNSRVQKLLSVLMDPKTASETETDICAEWEIKTITSALKTYLRMLPGPLMMYQFQRSFI Q1JPR9_DANRE Q1JPR9_DANRE GVSSKVQKLLSLMIDEKS-SDIDLSANEDWDVKTITSALKLYLRSLPEPLMTYELYKEFI Q4RKL2_TETNG Q4RKL2_TETNG GVSSKVQKLLTLKIDEKA-SEVDLSANDDWDIKTITSSLKLYLRSLPEPLMTYGLYKEFI Q2TAT2_XENLA Q2TAT2_XENLA GVSSKVQRLLSLLIDVKTCCDVDLDSSEEWEVKTVTSALKLYLRSLPEPLMTHELHDQFV Q6DEE5_XENLA Q6DEE5_XENLA GVSSKVQRLLSLLIDVKTCCDVDLDNSEEWEVKTVTSALKLYLRSLPEPLMTYEMHDQFI RHG10_MOUSE RHG10_MOUSE GVSSKVQRLLSMLMDVKMCNELDLENSADWEVKTVTSALKQYLRSLPEPLMTYELHRDFI RHG10_BOVIN RHG10_BOVIN GVSSKVQRLLSMLMDVKTCNEVDLENSVDWEVKTITSALKQYLRSLPEPLMTYELHGDFI B3KVP5_HUMAN B3KVP5_HUMAN GVSSKVQRLLSMLMDVKTCNEVDLENSADWEVKTITSALKQYLRSLPEPLMTYELHGDFI B4E2W2_HUMAN B4E2W2_HUMAN GVSSKVQRLLSMLMDVKTCNEVDLENSADWEVKTITSALKQYLRSLPEPLMTYELHGDFI Q86T21_HUMAN Q86T21_HUMAN --------LFACSLDVKTCNEVDLENSADWEVKTITSALKQYLRSLPEPLMTYELHGDFI RHG10_HUMAN RHG10_HUMAN GVSSKVQRLLSMLMDVKTCNEVDLENSADWEVKTITSALKQYLRSLPEPLMTYELHGDFI Q3KQX3_HUMAN Q3KQX3_HUMAN ------------------------------------------------------------ Q8ND72_HUMAN Q8ND72_HUMAN ---------------------------------TITSALKQYLRSLPEPLMTYELHGDFI Q6IA27_HUMAN Q6IA27_HUMAN ------------------------------------------------------------ Q9H7G7_HUMAN Q9H7G7_HUMAN ------------------------------------------------------------ A2CEG8_DANRE A2CEG8_DANRE GSNIQVQKLLNAFFDSKCPADVDFN-SSDMDIKTITSALKFYLRSLSEPLMTYSLHGELI B1AV63_MOUSE B1AV63_MOUSE GSNIQVQKLLYAFFDPKCPGDVDFH-NSDWDIKTITSSLKFYLRNLSEPVMTYKLHKELV OPHN1_MOUSE OPHN1_MOUSE GSNIQVQKLLYAFFDPKCPGDVDFH-NSDWDIKTITSSLKFYLRNLSEPVMTYKLHKELV Q8C4C7_MOUSE Q8C4C7_MOUSE GSNIQVQKLLYAFFDPKCPGDVDFH-NSDWDIKTITSSLKFYLRNLSEPVMTYKLHKELV Q6R7Z1_CAVPO Q6R7Z1_CAVPO GSNIQVQKLLNAFFEPKCPGNVDFH-NSDWDIKTITSSLKFYLGNLSEPVMTYRLHKELV B4DIT2_HUMAN B4DIT2_HUMAN GSNIQVQKLLNAFFDPKCPGDVDFH-NSDWDIKTITSSLKFYLRNLSEPDMTYRLHKELV B9EIP8_HUMAN B9EIP8_HUMAN GSNIQVQKLLNAFFDPKCPGDVDFH-NSDWDIKTITSSLKFYLRNLSEPVMTYRLHKELV OPHN1_PANTR OPHN1_PANTR GSNIQVQKLLNAFFDPKCPGDVDFH-NSDWDIKTITSSLKFYLRNLSEPVMTYRLHKELV OPHN1_PONPY OPHN1_PONPY GSNIQVQKLLNAFFDPKCPGDVDFH-NSDWDIKTITSSLKFYLRNLSEPVMTYRLHKELV OPHN1_HUMAN OPHN1_HUMAN GSNIQVQKLLNAFFDPKCPGDVDFH-NSDWDIKTITSSLKFYLRNLSEPVMTYRLHKELV Q0P4U1_XENTR Q0P4U1_XENTR GSNIQVQKLLNAFFDPKCPGNVDLQ-NSEWDIKTITSSLKFYLRNLSEPVMTYKLHRDLV Q6PCK6_XENLA Q6PCK6_XENLA GSNIQVQKLLNAFFDSKCPGNVDLQ-SSEWDIKTVTSSLKFYLRNLSEPVMTYKLHRDLV Q4RFN2_TETNG Q4RFN2_TETNG ----------SILCKVRGPPGGEVA-------------------CLSEPLMTFKLHKDFI Q4SFS4_TETNG Q4SFS4_TETNG GVNSKVQRLMTTVFASTAPADLHLD-ADAWDNKTITSGLKDYFRCLAEPVLTYRLHKEFI RH10L_DANRE RH10L_DANRE GVNSKVQRLMTSVFAAKAPADLDLD-PDTWDNKTITSGLKNYLRCLAEPLMTYRLHKDFI B2RQE8_MOUSE B2RQE8_MOUSE GVNSKVQKLMNTTFSPKSPPDMDID-IELWDNKTITSGLKNYLRCLAEPLMTYKLHKDFI Q0V8I4_BOVIN Q0V8I4_BOVIN ---------MNTTFSPKSPPDMDID-IELWDNKTITSGLKNYLRCLAEPLMTYKLHKDFI RH10L_HUMAN RH10L_HUMAN GVNSKVQKLMNTTFSPKSPPDIDID-IELWDNKTITSGLKNYLRCLAEPLMTYKLHKDFI YK021_HUMAN YK021_HUMAN GVNSKVQKLMNTTFSPKSPPDIDID-IELWDNKTITSGLKNYLRCLAEPLMTYKLHKDFI MATCH CONSENSUS G????VQ?L???????K????????????W??KT?TS?LK?YLR?L??P?M?Y???????

Q4RIS0_TETNG Q4RIS0_TETNG KAAKLDNPEARVKEIHALVHRLPEKNRQMLELLMNHLAN------VASHDQHNLMTVANL RHG26_XENLA RHG26_XENLA KAAKQESQESRIKEIHCLIHRLPEKNRQMLHLLMTHLAN------VAAHHKQNLMTVANL RHG26_XENTR RHG26_XENTR KAAKLENQESRIKEIHCLIHRLPEKNRQMLNLLMTHLAN------VAAHHKQNLMTVANL RHG26_CHICK RHG26_CHICK KAAKLENQESRVSEIHSLVHRLPEKNRQMLHLLMNHLAK------VADNHKQNLMTVANL B7NZB3_RABIT B7NZB3_RABIT KAAKLENQETRVSEIHSLVHRLPEKNRQMLQLLMNHLAN------VANNHKQNLMTVANL B9EJ96_MOUSE B9EJ96_MOUSE KAAKLENQETRVSEIHSLVHRLPEKNRQMLQLLMNHLAN------VANNHKQNLMTVANL RHG26_MOUSE RHG26_MOUSE KAAKLENQETRVSEIHSLVHRLPEKNRQMLQLLMNHLAN------VANNHKQNLMTVANL Q5D035_HUMAN Q5D035_HUMAN KAAKLENQESRVSEIHSLVHRLPEKNRQMLQLLMNHLAN------VANNHKQNLMTVANL RHG26_HUMAN RHG26_HUMAN KAAKLENQESRVSEIHSLVHRLPEKNRQMLQLLMNHLAN------VANNHKQNLMTVANL Q1JPR9_DANRE Q1JPR9_DANRE VPAKSASPESRVQAIHCLVHKLPEKNRLVLSLVTKHLAN------VAANSKQNLMTVANL Q4RKL2_TETNG Q4RKL2_TETNG SPAMSAVGDA-------------------------------------------------- Q2TAT2_XENLA Q2TAT2_XENLA NPAKSGSPESRVTSIHHLIHQLPEKNREMLDILITHLAN------VARHAKQNLMTVANL Q6DEE5_XENLA Q6DEE5_XENLA NLAKSGSPESRVNAIHILIHKLPEKNREMLDILITHLAN------VAHHAKKNLMTVANL RHG10_MOUSE RHG10_MOUSE VPAKSGSPESRVNAIHFLVHKLPEKNKEMLDILVKHLTN------VSSHSKQNLMTVANL RHG10_BOVIN RHG10_BOVIN VPAKSGSPESRVNAIHFLVHKLPEKNKEMLDILVKHLTN------VSNHSKQNLMTVANL B3KVP5_HUMAN B3KVP5_HUMAN VPAKSGSPESRVNAIHFLVHKLPEKNKEMLDILVKHLTN------VSNHSKQNLMTVANL B4E2W2_HUMAN B4E2W2_HUMAN VPAKSGSPESRVNAIHFLVHKLPEKNKEMLDILVKHLTN------VSNHSKQNLMTVANL Q86T21_HUMAN Q86T21_HUMAN VPAKSGSPESRVNAIHFLVHKLPEKNKEMLDILVKHLTN------VSNHSKQNLMTVANL RHG10_HUMAN RHG10_HUMAN VPAKSGSPESRVNAIHFLVHKLPEKNKEMLDILVKHLTN------VSNHSKQNLMTVANL Q3KQX3_HUMAN Q3KQX3_HUMAN ------------------------------------------------------------ Q8ND72_HUMAN Q8ND72_HUMAN VPAKSGSPESRVNAIHFLVHKLPEKNKEMLDILVKHLTN------VSNHSKQNLMTVANL Q6IA27_HUMAN Q6IA27_HUMAN ------------------------------------------------------------ Q9H7G7_HUMAN Q9H7G7_HUMAN ------------------------------------------------------------ A2CEG8_DANRE A2CEG8_DANRE LAAKSENLDYRLGAVHSLVYKLPERNREMLELLIKQLCV------VCSHSSENLMTVSNM B1AV63_MOUSE B1AV63_MOUSE SAAKSDNLDYRLGAIHSLVYKLPEKNREMLELLIKHLVN------VCEHSKENLMTPSNM OPHN1_MOUSE OPHN1_MOUSE SAAKSDNLDYRLGAIHSLVYKLPEKNREMLELLIKHLVN------VCEHSKENLMTPSNM Q8C4C7_MOUSE Q8C4C7_MOUSE SAAKSDNLDYRLGAIHSLVYKLPEKNREMLELLIKHLVN------VCEHSKENLMTPSNM Q6R7Z1_CAVPO Q6R7Z1_CAVPO SAAKSDNLDYRLGAIHSLVYKLPEKNREMLELLIRHLVN------VCEHSKENLMTPSNM B4DIT2_HUMAN B4DIT2_HUMAN SAAKSDNLDYRLGAIHSLVYKLPEKNREMLELLIRHLVN------VCEHSKENLMTPSNM B9EIP8_HUMAN B9EIP8_HUMAN SAAKSDNLDYRLGAIHSLVYKLPEKNREMLELLIRHLVN------VCEHSKENLMTPSNM OPHN1_PANTR OPHN1_PANTR SAAKSDNLDYRLGAIHSLVYKLPEKNREMLELLIRHLVN------VCEHSKENLMTPSNM OPHN1_PONPY OPHN1_PONPY SAAKSDNLDYRLGAIHSLVYKLPEKNREMLELLIRHLVN------VCEHSKENLMTPSNM OPHN1_HUMAN OPHN1_HUMAN SAAKSDNLDYRLGAIHSLVYKLPEKNREMLELLIRHLVN------VCEHSKENLMTPSNM Q0P4U1_XENTR Q0P4U1_XENTR LASKSENLDYRLGAIHCLVYRLPENHREMLELIIRHLSR------VCEFSRENLMSPSNM Q6PCK6_XENLA Q6PCK6_XENLA LAAKSENLDYRLGAIHCLVYRLPENHREMLELIIRHLSR------VCEFSKENLMSPSNM Q4RFN2_TETNG Q4RFN2_TETNG MAVKSDDQNYRVCAVHALVHKLPEKNREMLELLIKHLVTYF----SSLRMQMSLFLNLRA Q4SFS4_TETNG Q4SFS4_TETNG KAAKYDDQKYRVRAIHALVHKLPERNRTLLDLLTSHLHKYVSMDTVSSHCSQNLMTVSNL RH10L_DANRE RH10L_DANRE MAVKSDDQNYRVCAVHALVYKLPDKNKEMLNLLIKHLHV------VSTHSQKNLMTVSNL B2RQE8_MOUSE B2RQE8_MOUSE IAVKSDDQNYRVEAVHALVHKLPEKNREMLDILIKHLLK------VSLHSQQNLMTISNL Q0V8I4_BOVIN Q0V8I4_BOVIN VAVKSDDQNYRVEAVHALVHKLPEKNREMLDILIKHLVK------VSLHSQQNLMTVSNL RH10L_HUMAN RH10L_HUMAN IAVKSDDQNYRVEAVHALVHKLPEKNREMLDILIKHLVK------VSLHSQQNLMTVSNL YK021_HUMAN YK021_HUMAN IAVKSDDQNYRVEAVHALVHKLPEKNREMLDILIKHLVK------VSLHSQQNLMTVSNL MATCH CONSENSUS ???K??????R????H?LV??LPEKN??ML??L??HL????????V??????NLMT??N?

Q4RIS0_TETNG Q4RIS0_TETNG GVVF---GPTLLRPQEETVAA---------IMDIKFQNIVV------EILIEHHERIFSD RHG26_XENLA RHG26_XENLA GVVF---GPTLLRPQEETVAA---------IMDIKFQNIVV------EIIIENYEEMFST RHG26_XENTR RHG26_XENTR GIVF---GPTLLRPQEETVAA---------IMDIKFQNIVV------EIIIENYEKMFST RHG26_CHICK RHG26_CHICK GVVF---GPTLLRPQEETVAA---------IMDIKFQNIVI------EILIENHEKIFNT B7NZB3_RABIT B7NZB3_RABIT GVVF---GPTLLRPQEETVAA---------IMDIKFQNIVI------EILIENHEKIFNT B9EJ96_MOUSE B9EJ96_MOUSE GVVF---GPTLLRPQEETVAA---------IMDIKFQNIVI------EILIENHEKIFNT RHG26_MOUSE RHG26_MOUSE GVVF---GPTLLRPQEETVAA---------IMDIKFQNIVI------EILIENHEKIFNT Q5D035_HUMAN Q5D035_HUMAN GVVF---GPTLLRPQEETVAA---------IMDIKFQNIVI------EILIENHEKIFNT RHG26_HUMAN RHG26_HUMAN GVVF---GPTLLRPQEETVAA---------IMDIKFQNIVI------EILIENHEKIFNT Q1JPR9_DANRE Q1JPR9_DANRE GVVF---GPTLMRPQEETVAA---------IMDLKFQNIVV------EILIEQHEKIFGD Q4RKL2_TETNG Q4RKL2_TETNG ------------------------------------------------------------ Q2TAT2_XENLA Q2TAT2_XENLA GVVF---GPTLMRPQEETVAA---------IMDLKFQNIVV------EILIENHEKIFKN Q6DEE5_XENLA Q6DEE5_XENLA GVVF---GPTLMRPQEETVAA---------IMDLKFQNIVV------DILIQSHEKIFKN RHG10_MOUSE RHG10_MOUSE GVVF---GPTLMRPQEETVAA---------IMDLKFQNIVV------EILIENHEKIFRT RHG10_BOVIN RHG10_BOVIN GVVF---GPTLMRPQEETVAA---------IMDLKFQNIVV------EILIENHEKIFRT B3KVP5_HUMAN B3KVP5_HUMAN GVVF---GPTLMRPQEETVAA---------LMDLKFQNIVV------EILIENHEKIFRT B4E2W2_HUMAN B4E2W2_HUMAN GVVF---GPTLMRPQEETVAA---------LMDLKFQNIVV------EILIENHEKIFRT Q86T21_HUMAN Q86T21_HUMAN GVVF---GPTLMRPQEETVAA---------LMDLKFQNIVV------EILIENHEKIFRT RHG10_HUMAN RHG10_HUMAN GVVF---GPTLMRPQEETVAA---------LMDLKFQNIVV------EILIENHEKIFRT Q3KQX3_HUMAN Q3KQX3_HUMAN --------------------------------DLKFQNIVV------EILIENHEKIFRT Q8ND72_HUMAN Q8ND72_HUMAN GVVF---GPTLMRPQEETVAA---------LMDLKFQNIVV------EILIENHEKIFRT Q6IA27_HUMAN Q6IA27_HUMAN -------------------------------------------------------KIFRT Q9H7G7_HUMAN Q9H7G7_HUMAN -------------------------------------------------------KIFRT A2CEG8_DANRE A2CEG8_DANRE GVIF---GPTLMRAEEETVAA---------MLDIKFQNIVM------EILIEDYSKIFKG B1AV63_MOUSE B1AV63_MOUSE GVIF---GPTLMRAQEDTVAA---------MMNIKFQNIVV------EILIEHFGKIYLG OPHN1_MOUSE OPHN1_MOUSE GVIF---GPTLMRAQEDTVAA---------MMNIKFQNIVV------EILIEHFGKIYLG Q8C4C7_MOUSE Q8C4C7_MOUSE GVIF---GPTLMRAQEDTVAA---------MMNIKFQNIVV------EILIEHFGKIYLG Q6R7Z1_CAVPO Q6R7Z1_CAVPO GVIF---GPTLMRAQEDTVAA---------MMNTKFQNIVV------EILIEHFGKIYLG B4DIT2_HUMAN B4DIT2_HUMAN GVIF---GPTLMRAQEDTVAA---------MMNIKFQNIVV------EILIEHFGKIYLG B9EIP8_HUMAN B9EIP8_HUMAN GVIF---GPTLMRAQEDTVAA---------MMNIKFQNIVV------EILIEHFGKIYLG OPHN1_PANTR OPHN1_PANTR GVIF---GPTLMRAQEDTVAA---------MMNIKFQNIVV------EILIEHFGKIYLG OPHN1_PONPY OPHN1_PONPY GVIF---GPTLMRAQEDTVAA---------MMNIKFQNIVV------EILIEHFGKIYLG OPHN1_HUMAN OPHN1_HUMAN GVIF---GPTLMRAQEDTVAA---------MMNIKFQNIVV------EILIEHFGKIYLG Q0P4U1_XENTR Q0P4U1_XENTR GVIF---GPTLMRAQEDTVAA---------MMNIKFQNIVV------ELLIENCKKIFSG Q6PCK6_XENLA Q6PCK6_XENLA GVIF---GPTLMRAQEDTVAA---------MMNIKFQNIVV------ELLIENCKKIFSG Q4RFN2_TETNG Q4RFN2_TETNG GLIHAGTGPSVCPQDPGSPAASTPQLCAWQMQKVSTKAVFITTYNFPQVVAGHYKKTAHL Q4SFS4_TETNG Q4SFS4_TETNG GMIF---GPTLMRSQEET--------------------------------------IFGE RH10L_DANRE RH10L_DANRE GVIF---GPTLMRSQEETVAA---------MMNIKFQNIVV------EILIENYDKIFHQ B2RQE8_MOUSE B2RQE8_MOUSE GVIF---GPTLMRAQEETVAA---------MMNIKFQNIVV------EILIEHYEKIFHT Q0V8I4_BOVIN Q0V8I4_BOVIN GVIF---GPTLMRAQEETVAA---------MMNIKFQNIVV------EILIEHYEKIFHT RH10L_HUMAN RH10L_HUMAN GVIF---GPTLMRAQEETVAA---------MMNIKFQNIVV------EILIEHYEKIFHT YK021_HUMAN YK021_HUMAN GVIF---GPTLMRAQEETVAA---------MMNIKFQNIVV------EILIEHYEKIFHT MATCH CONSENSUS GV?F???GPTL?R?QE?TVAA??????????M??KFQNIV???????EILIE???KI???

Q4RIS0_TETNG Q4RIS0_TETNG VPSPATGPSNL----QLNLSRRKSTDSKAPSCSERPLTLFPT---------PTHSLKGEK RHG26_XENLA RHG26_XENLA VPE------MPQTNSQLHLSRKRSTDSKPPSCSERPLTLFHTSHS-------------SE RHG26_XENTR RHG26_XENTR VPE------MPQTNSQLHLSRKRSSDSKPPSCSERPLTLFHTTHN-------------TE RHG26_CHICK RHG26_CHICK VPE------TPPSNSQLLLSRKKSTDSKPPSCSERPLTLFHTAQP-------------NE B7NZB3_RABIT B7NZB3_RABIT VPD------APLTGTQLHLSRKKSGDAKPPSCSERPLTLFHAVQA-------------TE B9EJ96_MOUSE B9EJ96_MOUSE VPD------VPLTNAQLHLSRKKSSDSKPPSCSERPLTLFHAVPS-------------TE RHG26_MOUSE RHG26_MOUSE VPD------VPLTNAQLHLSRKKSSDSKPPSCSERPLTLFHAVPS-------------TE Q5D035_HUMAN Q5D035_HUMAN VPD------MPLTNAQLHLSRKKSSDSKPPSCSERPLTLFHTVQS-------------TE RHG26_HUMAN RHG26_HUMAN VPD------MPLTNAQLHLSRKKSSDSKPPSCSERPLTLFHT------------------ Q1JPR9_DANRE Q1JPR9_DANRE APSSSPSLATT----PLSAPTRQSKRL---SRQTRPLAVYNPQVLDIQTVSPSSESAGLC Q4RKL2_TETNG Q4RKL2_TETNG -SS-------------------------------------------------------IT Q2TAT2_XENLA Q2TAT2_XENLA PPSGLEAESDSLSISPPNAPPRQSRR----QHRKRPVPVYNL--SLELDNADMHL---TP Q6DEE5_XENLA Q6DEE5_XENLA PPSGLEAELDSQSISPPNAPPRQSRR----QHRKRPVPVYDL--SLELDNADMIL---TP RHG10_MOUSE RHG10_MOUSE SPDTTFAEPTCLSASPPNAPPRQSKR--QGQRTKRPVAVYNL--CLELEEGDSPS---PL RHG10_BOVIN RHG10_BOVIN PPDATLPEPGPLSA-PPNAPPRQSKR--QGQRTKRPVAVYNL--CLELEDGDRPS---LP B3KVP5_HUMAN B3KVP5_HUMAN PPDTTFPEPTCLSASPPNAPPRQSKR--QGQRTKRPVAVYNL--CLELEDGDNPY---PS B4E2W2_HUMAN B4E2W2_HUMAN PPDTTFPEPTCLSASPPNAPPRQSKR--QGQRTKRPVAVYNL--CLELEDGDNPY---PS Q86T21_HUMAN Q86T21_HUMAN PPDTTFPEPTCLSASPPNAPPRQSKR--QGQRTKRPVAVYNL--CLELEDGDNPY---PS RHG10_HUMAN RHG10_HUMAN PPDTTFPEPTCLSASPPNAPPRQSKR--QGQRTKRPVAVYNL--CLELEDGDNPY---PS Q3KQX3_HUMAN Q3KQX3_HUMAN PPDTTFPEPTCLSASPPNAPPRQSKR--QGQRTKRPVAVYNL--CLELEDGDNPY---PS Q8ND72_HUMAN Q8ND72_HUMAN PPDTTFPEPTCLSASPPNAPPRQSKR--QGQRTKRPVAVYNL--CLELEDGDNPY---PS Q6IA27_HUMAN Q6IA27_HUMAN PPDTTFPEPTCLSASPPNVPPRQSKR--QGQRTKRPVAVYNL--CLELEDGDNPY---PS Q9H7G7_HUMAN Q9H7G7_HUMAN PPDTTFPEPTCLSASPPNAPPRQSKR--QGQRTKRPVAVYNL--CLELEDGDNPY---PS A2CEG8_DANRE A2CEG8_DANRE PPEESVPPPVP----PPRVSPRRRQPITISKRPARVYTGLQP----------------PA B1AV63_MOUSE B1AV63_MOUSE PPEDSQVPPVP----PPRVTARRHKPITISKRLLREKTVFYT----------------SS OPHN1_MOUSE OPHN1_MOUSE PPEDSQVPPVP----PPRVTARRHKPITISKRLLREKTVFYT----------------SS Q8C4C7_MOUSE Q8C4C7_MOUSE PPEDSQVPPVP----PPRVTARRHKPITISKRLLREKTVFYT----------------SS Q6R7Z1_CAVPO Q6R7Z1_CAVPO PPEESAAPPVP----PPRVTARRHKSITISKRLLRERTVFYT----------------SS B4DIT2_HUMAN B4DIT2_HUMAN PPEESAAPPVP----PPRVTARRHKPITISKRLLRERTVFYT----------------SS B9EIP8_HUMAN B9EIP8_HUMAN PPEESAAPPVP----PPRVTARRHKPITISKRLLRERTVFYT----------------SS OPHN1_PANTR OPHN1_PANTR PPEESAAPPVP----PPRVTARRHKPITISKRLLRERTVFYT----------------SS OPHN1_PONPY OPHN1_PONPY PPEESAAPPVP----PPRVTARRHKPITISKRLLRERTVFYT----------------SS OPHN1_HUMAN OPHN1_HUMAN PPEESAAPPVP----PPRVTARRHKPITISKRLLRERTVFYT----------------SS Q0P4U1_XENTR Q0P4U1_XENTR PLDDNCGPPVP----PPRITPRTHIPITISKRQARGRSGLQL-----------------G Q6PCK6_XENLA Q6PCK6_XENLA PLDDNSGPPVP----PPRITPRTHIPITISKRQTRGRGGLHL-----------------G Q4RFN2_TETNG Q4RFN2_TETNG DTFYSHKMSYP--------------AFDKWIGFNGDLAYLYSGPCIGDTLS-------SS Q4SFS4_TETNG Q4SFS4_TETNG APDLSLPLPQA---PSSRSTPRRNKAICLSSGKRRAR-LYPPALCLADNDSDTFS---SS RH10L_DANRE RH10L_DANRE APDPNVPLPHPQSHSQSRGGARRSKAICLSSGSRKSRGLYPPALCLADADSDTFS---SS B2RQE8_MOUSE B2RQE8_MOUSE APDPNIPLPQP----QSRSGSRRTRAICLSTGSRKPRGRYTP--CLAEPDSDSYS---SS Q0V8I4_BOVIN Q0V8I4_BOVIN APDPSIPLPQP----QSRSGSRRTRAICLSSGSRKPRGRYTP--CLAEPDSDSYS---SS RH10L_HUMAN RH10L_HUMAN APDPSIPLPQP----QSRSGSRRTRAICLSTGSRKPRGRYTP--CLAEPDSDSYS---SS YK021_HUMAN YK021_HUMAN APDPSIPLPQP----QSRSGSRRTRAICLSTGSRKPRGRYTP--CLAEPDSDSYS---SS MATCH CONSENSUS ?P????????????????????????????????R?????????????????????????

Q4RIS0_TETNG Q4RIS0_TETNG RDSLA-NATVAEPPSADCN--------SSSGSN--NSSSSQ------------------G RHG26_XENLA RHG26_XENLA KEEKR-NSVNSSAESVSSS--------NANSSVNSTCTQRS------------------- RHG26_XENTR RHG26_XENTR KEEKR-NSVNSSAESVSSS--------NANSSANSTCTQCS------------------- RHG26_CHICK RHG26_CHICK KQESR-NSIINSSLESVIS--------SNANSFL-NSNSAP------------------- B7NZB3_RABIT B7NZB3_RABIT KQEQR-NSILNSSLESVSS--------NPNSIL--NSSSSL------------------- B9EJ96_MOUSE B9EJ96_MOUSE KQEQR-NSIINSSLESVSS--------SANSIL--NSSSSL------------------- RHG26_MOUSE RHG26_MOUSE KQEQR-NSIINSSLESVSS--------SANSIL--NSSSSL------------------- Q5D035_HUMAN Q5D035_HUMAN KQEQR-NSIINSSLESVSS--------NPNSIL--NSSSSL------------------- RHG26_HUMAN RHG26_HUMAN VQSTEKQEQRNSIINSSLE--------SVSSNPNSILNSSS------------------S Q1JPR9_DANRE Q1JPR9_DANRE NDETS-VGSNESVSSQSSN--------ASGTPP--------------------------- Q4RKL2_TETNG Q4RKL2_TETNG TDETS-MGSNESVSSQSS---------SASETP--------------------------- Q2TAT2_XENLA Q2TAT2_XENLA REDTP-TGSTDSLSPQSLT----------PTPPHTNPTADE------------------- Q6DEE5_XENLA Q6DEE5_XENLA REDTP-TGSTDSLSPQSLT--------PTTPHP--NPTADE------------------- RHG10_MOUSE RHG10_MOUSE KEDPP-SSSQDSLSTPSPT--------TSAAH---GPPGLD------------------- RHG10_BOVIN RHG10_BOVIN KEDTP-PSSLDSLSSPSPT--------TATAL---GHPGPD------------------- B3KVP5_HUMAN B3KVP5_HUMAN KEDTP-TSSLDSLSSPSPV---------TTAVP--GPPGPD------------------- B4E2W2_HUMAN B4E2W2_HUMAN KEDTP-TSSLDSLSSPSPV--------TTAVP---GPPGPD------------------- Q86T21_HUMAN Q86T21_HUMAN KEDTP-TSSLDSLSSPSPV--------TTAVP---GPPGPD------------------- RHG10_HUMAN RHG10_HUMAN KEDTP-TSSLDSLSSPSPV--------TT-AVP--GPPGPD------------------- Q3KQX3_HUMAN Q3KQX3_HUMAN KEDTP-TSSLDSLSSPSPV--------TT-AVP--GPPGPD------------------- Q8ND72_HUMAN Q8ND72_HUMAN KEDTP-TSSLDSLSSPSPV--------TT-AVP--GPPGPD------------------- Q6IA27_HUMAN Q6IA27_HUMAN KEDTP-TSSLDSLSSPSPV--------TTAVP---GPPGPD------------------- Q9H7G7_HUMAN Q9H7G7_HUMAN KEDTP-TSSLDSLSSPSPV--------TT-AVP--GPPGPD------------------- A2CEG8_DANRE A2CEG8_DANRE FERRELNGATHNNGEPEGD--------GGPVPQQRTKLIPP------------------S B1AV63_MOUSE B1AV63_MOUSE LDENK-DESHHQTPNGTIT--------SNLDPP--KLLQHL------------------- OPHN1_MOUSE OPHN1_MOUSE LDENK-DESHHQTPNGTIT--------SNLDPP--KLLQHL------------------- Q8C4C7_MOUSE Q8C4C7_MOUSE LDENK-DESHHQTPNGTIT--------SNLDPP--KLLQHL------------------- Q6R7Z1_CAVPO Q6R7Z1_CAVPO MDESE-DEIQHQTPNGTIT--------SSIEPP--KPPQHP------------------- B4DIT2_HUMAN B4DIT2_HUMAN LDESE------------------------------------------------------- B9EIP8_HUMAN B9EIP8_HUMAN LDESE-DEIQHQTPNGTIT--------SSIEPP--KPPQHP------------------- OPHN1_PANTR OPHN1_PANTR LDESE-DEIQHQTPNGTIT--------SSIEPP--KPPQHP------------------- OPHN1_PONPY OPHN1_PONPY LDESE-DEIQHQTPNGTIT--------SSIEPP--KPPQHP------------------- OPHN1_HUMAN OPHN1_HUMAN LDESE-DEIQHQTPNGTIT--------SSIEPP--KPPQHP------------------- Q0P4U1_XENTR Q0P4U1_XENTR QSEEE-DELPGHALNGSVT--------NNHEYP--LPLQRK------------------- Q6PCK6_XENLA Q6PCK6_XENLA QSEEE-DELPGHTLNGSVT--------NNHEYP--LPLQRK------------------K Q4RFN2_TETNG Q4RFN2_TETNG PSSTP-MGSLESLSSHSSE----------------------------------------- Q4SFS4_TETNG Q4SFS4_TETNG PETTP-MGSRESLSSHSSEKNGQTLLSSPPSSPTTEASLSPAATASPPAASSQYCSNGNG RH10L_DANRE RH10L_DANRE PSSTP-MGSMESLSSHSSE--------QNSCSKTGSPSRNK------------------H B2RQE8_MOUSE B2RQE8_MOUSE PDSTP-MGSIESLSSHSSEQNSTTK--STACQPREKSGGIP------------------W Q0V8I4_BOVIN Q0V8I4_BOVIN PDSTP-MGSIESLSSHSSEQNSTTK--PASCQPREKSTGIP------------------W RH10L_HUMAN RH10L_HUMAN PDSTP-MGSIESLSSHSSEQNSTTK--SASCQPREKSGGIP------------------W YK021_HUMAN YK021_HUMAN PDSTP-MGSIESLSSHSSEQNSTTK--SASCQPREKSGGIP------------------W MATCH . CONSENSUS ????????????????????????????????????????????????????????????

Q4RIS0_TETNG Q4RIS0_TETNG RTPRHSLNSNDAEQDARHTRPSSLLNPKSRSSIPTSAPSPSPTSPRSPSWPMFSAP--SS RHG26_XENLA RHG26_XENLA -NMNNLNASDPDLDVAKVSRPNSL----------------------------------LN RHG26_XENTR RHG26_XENTR -NMNNLNASDPDLDVAKASRPNSL------------SLNPSPTSP--PTCPMFSAP--SS RHG26_CHICK RHG26_CHICK -QSNL-NSSDLELEVIKPNRPNSL------------PQNPSPTSPLSPSWPMFSAP--SS B7NZB3_RABIT B7NZB3_RABIT -QPNT-NSSDLDLDVVKPARPNSL------------------------------------ B9EJ96_MOUSE B9EJ96_MOUSE -QPNL-NSSDSNLDVVKPSRPSSL------------------------------------ RHG26_MOUSE RHG26_MOUSE -QPNL-NSSDSNLDVVKPSRPSSL------------PPNPSPTSPLSPSWPMFSAP--SS Q5D035_HUMAN Q5D035_HUMAN -QPNM-NSSDPDLAVVKPTRPNSL------------PPNPSPTSPLSPSWPMFSAP--SS RHG26_HUMAN RHG26_HUMAN LQPNM-NSSDPDLAVVKPTRPNSL------------PPNPSPTSPLSPSWPMFSAP--SS Q1JPR9_DANRE Q1JPR9_DANRE ------EKSKNHHTTISTSLQEGT------------GICTATASWMNS----------AS Q4RKL2_TETNG Q4RKL2_TETNG -----------------TDRPIES--------------SEHAPLCCSLSSGSNKSS--SA Q2TAT2_XENLA Q2TAT2_XENLA -RNHI-TANIGSPADWSASERNLI--------------HSPLVLWINDESPAASAV--TT Q6DEE5_XENLA Q6DEE5_XENLA -RNHI-MANIVGLVDWSEKNLIHS----------------HLVSWINDESPAASTV--PT RHG10_MOUSE RHG10_MOUSE -GNHL-AADGGSCGDATATTPSQT--------------RPSMVQWLNMQSP--TTP--SS RHG10_BOVIN RHG10_BOVIN -RNHL-LTDGGSFGDWAPTAPSQA--------------RSSAVQWLNPQSP--TTP--SC B3KVP5_HUMAN B3KVP5_HUMAN -KNHL-LADGGSFGDWASTI---------------------------------------- B4E2W2_HUMAN B4E2W2_HUMAN -KNHL-LADGGSFGDWASTIPGQT--------------RSSMVQWLNPQSP--TTT--SS Q86T21_HUMAN Q86T21_HUMAN -KNHL-LADGGSFGDWASTIPGQT--------------RSSMVQWLNPQSP--TTT--SS RHG10_HUMAN RHG10_HUMAN -KNHL-LADGGSFGDWASTIPGQT--------------RSSMVQWLNPQSP--TTT--SS Q3KQX3_HUMAN Q3KQX3_HUMAN -KNHL-LADGGSFGDWASTIPGQT--------------RSSMVQWLNPQSP--TTT--SS Q8ND72_HUMAN Q8ND72_HUMAN -KNHL-LADGGSFGDWASTIPGQT--------------RSSMVQWLNPQSP--TTT--SS Q6IA27_HUMAN Q6IA27_HUMAN -KNHL-LADGGSFGDWASTIPGQT--------------RSSMVQWLNPQSP--TTT--SS Q9H7G7_HUMAN Q9H7G7_HUMAN -KNHL-LADGGSFGDWASTIPGQT--------------RSSMVQWLNPQSP--TTT--SS A2CEG8_DANRE A2CEG8_DANRE ISPPSIPLSSPTSRRPLHPRPAVR-----------LLEPEVSRFDARIQDGLRSDA--TT B1AV63_MOUSE B1AV63_MOUSE -KPPMQKSGETDPGRKSPSRPVSD------CQSEPCLETDVGRLLFRLQDG--GTK--AT OPHN1_MOUSE OPHN1_MOUSE -KPPMQKSGETDPGRKSPSRPVSD------CQSEPCLETDVGRLLFRLQDG--GTK--AT Q8C4C7_MOUSE Q8C4C7_MOUSE -KPPMQKSGETDPGRKSPSRPVSD------CQSEPCLETDVGRLLFRLQDG--GTK--AT Q6R7Z1_CAVPO Q6R7Z1_CAVPO -KLPIQRSGETDPGRKSPSRPILD------GKLEPCPEVDVGKLVSGLQDG--GTK--IT B4DIT2_HUMAN B4DIT2_HUMAN ----------GDADSFSKVRPPGE------------------------------------ B9EIP8_HUMAN B9EIP8_HUMAN -KLPIQRSGETDPGRKSPSRPILD------GKLEPCPEVDVGKLVSRLQDG--GTK--IT OPHN1_PANTR OPHN1_PANTR -KLPIQRSGETDPGRKSPSRPISD------GKLEPCPEVDVGKLVSRLQDG--GTK--IT OPHN1_PONPY OPHN1_PONPY -KLPIQRSGETDPGRKSPSRPISD------GKLEPCPEVDVGKLVSRLQDG--GTK--IT OPHN1_HUMAN OPHN1_HUMAN -KLPIQRSGETDPGRKSPSRPILD------GKLEPCPEVDVGKLVSRLQDG--GTK--IT Q0P4U1_XENTR Q0P4U1_XENTR -KLLP-NLQRVD----TPSQSDSS------------SDVDVAKMVSRIQDG--SGK--AN Q6PCK6_XENLA Q6PCK6_XENLA LHPNLQML-------DTQGQSDSS------------SDVDVAKMVSRMQDG--NGK--PN Q4RFN2_TETNG Q4RFN2_TETNG -QNNSSK--------MAPSAQVKT-------------RALLPQTLSELSNGYRSAA--GT Q4SFS4_TETNG Q4SFS4_TETNG QKDPSAPPHLGTSSSWTSPQPTLT------------QQTSSVSSSMSSLLSTERTL--SA RH10L_DANRE RH10L_DANRE KASGSLCWTTPSPSTNGPKSPACT-----------TSPDSSSKEDANKTDGEWEEALSTS B2RQE8_MOUSE B2RQE8_MOUSE ITTPSSSNGQKSQGLWTTS-PESS------------SREDATKTDVESDCQSVASI--TI Q0V8I4_BOVIN Q0V8I4_BOVIN IASPSPSNGQKSLGLWTTS-PESS------------SREDATKTDAESDCQSVTSV--TS RH10L_HUMAN RH10L_HUMAN IATPSSSNGQKSLGLWTTS-PESS------------------------------------ YK021_HUMAN YK021_HUMAN IATPSSSNGQKSLGLWTTS-PESS------------SREDATKTDAESDCQSVASV--TS MATCH CONSENSUS ????????????????????P???????????????????????????????????????

Q4RIS0_TETNG Q4RIS0_TETNG PQRISSASSDS-SPVRSVGPSGLVSSAGCRVLRRPRSPARNISIASIDYFFFFFFFEHVV RHG26_XENLA RHG26_XENLA PKNISGLLPSSLNPSPTSPPTCPMVSAPSSPMPTSSTSSD-------------------- RHG26_XENTR RHG26_XENTR PMPTSSTSSDS-SP---------------------------------------------- RHG26_CHICK RHG26_CHICK PMPTSSTSSDS-SPI--------------------------------------------- B7NZB3_RABIT B7NZB3_RABIT ------------------------------------------------------------ B9EJ96_MOUSE B9EJ96_MOUSE ------------------------------------------------------------ RHG26_MOUSE RHG26_MOUSE PMPTSSTSSDS-SPIRSVAGFVWFSVAAVVLSLAWSSLHAVFSLLVNFVPCHPNLHLLFD Q5D035_HUMAN Q5D035_HUMAN PMPTSSTSSDS-SPV--------------------------------------------- RHG26_HUMAN RHG26_HUMAN PMPTSSTSSDS-SPVRSVAGFVWFSVAAVVLSLARSSLHAVFSLLVNFVPCHPNLHLLFD Q1JPR9_DANRE Q1JPR9_DANRE PASLTPVKHGS-VRTEKNKP---------------------------------------- Q4RKL2_TETNG Q4RKL2_TETNG AASWSGPAPSW-AAQPAAPIAAPEKE---------------------------------- Q2TAT2_XENLA Q2TAT2_XENLA SQAAEATPVKD-PEEPLTLPAHLLTTSDT------------------------------- Q6DEE5_XENLA Q6DEE5_XENLA SQAAEATPVRD-PEEALTLPEHLL------------------------------------ RHG10_MOUSE RHG10_MOUSE NPAGTPPSPRM-SPFPLSPAASIVDKLPE------------------------------- RHG10_BOVIN RHG10_BOVIN SPAVTPPSPKL-PPVPLSLPATVADKPPE------------------------------- B3KVP5_HUMAN B3KVP5_HUMAN ------------------------------------------------------------ B4E2W2_HUMAN B4E2W2_HUMAN NSAVTPLSPGS-SPFPFSPPATVADKPPE------------------------------- Q86T21_HUMAN Q86T21_HUMAN NSAVTPLSPGS-SPFPFSPPATVADKPPE------------------------------- RHG10_HUMAN RHG10_HUMAN NSAVTPLSPGS-SPFPFSPPATVADKPPE------------------------------- Q3KQX3_HUMAN Q3KQX3_HUMAN NSAVTPLSPGS-SPFPFSPPATVADKPPE------------------------------- Q8ND72_HUMAN Q8ND72_HUMAN NSAVTPLSPGS-SPFPFSPPATVADKPPE------------------------------- Q6IA27_HUMAN Q6IA27_HUMAN NSAVTPLSPGS-SPFPFSPPATVADKPPE------------------------------- Q9H7G7_HUMAN Q9H7G7_HUMAN NSAVTPLSPGS-SPFPFSPPATVADKPPE------------------------------- A2CEG8_DANRE A2CEG8_DANRE NGDSGGTVNRA-QSFQKRTQLKGTTGKQAAAAAGNSREAQGLKRRSFS------------ B1AV63_MOUSE B1AV63_MOUSE PKASNGPVPGS-GH-TKTSSFHIRRPAPRPMAHHKEGDTD-----------GFSKVRPPG OPHN1_MOUSE OPHN1_MOUSE PKASNGPVPGS-GH-TKTSSFHIRRPAPRPMAHHKEGDTD-----------GFSKVRPPG Q8C4C7_MOUSE Q8C4C7_MOUSE PKASNGPVPGS-GH-TKTSSFHIRRPAPRPMAHHKEGDTD-----------GFSKVRPPG Q6R7Z1_CAVPO Q6R7Z1_CAVPO PKATNGPMPGS-GP-TKTPSFHIKRPAPRPLAHHKEGDAD-----------SFSKVRPPG B4DIT2_HUMAN B4DIT2_HUMAN ------------------------------------------------------------ B9EIP8_HUMAN B9EIP8_HUMAN PKATNGPMPGS-GP-TKTPSFHIKRPAPRPLAHHKEGDAD-----------SFSKVRPPG OPHN1_PANTR OPHN1_PANTR PKATNGPMPGS-GP-TKTPSFHIKRPAPRPLAHHKEGDAD-----------SFSKVRPPG OPHN1_PONPY OPHN1_PONPY PKATNGPMPGS-GP-TKTPSFHIKRPAPRPLAHHKEGDAD-----------SFSKVRPPG OPHN1_HUMAN OPHN1_HUMAN PKATNGPMPGS-GP-TKTPSFHIKRPAPRPLAHHKEGDAD-----------SFSKVRPPG Q0P4U1_XENTR Q0P4U1_XENTR TKQLNGDLPVY-STATKPSALHPKRGPTRPAVPREAEGD------------NVNKVRSPG Q6PCK6_XENLA Q6PCK6_XENLA PKQLNGDLPVY-SAPNKPSPLHPKRGPIRPAVPREGEGD------------NINKVRSPG Q4RFN2_TETNG Q4RFN2_TETNG SSLESSSREEA-KHTDVDLEDTRSLSSFS------------------------------- Q4SFS4_TETNG Q4SFS4_TETNG KGSSNASLSSI-KESRVPSGASSVTSTQCSSVEHTSSPREGRAIQRGSSLSSLKSSCSAD RH10L_DANRE RH10L_DANRE PGDRSSPASEL-LHRTLGETAEDQRSLSSCSSLTSLHISEGFRSCHG------------- B2RQE8_MOUSE B2RQE8_MOUSE PGNVSPPIDLV-KKGPYGLSGLKRSSASS--SLRSISAAEGNKSYSG----SIQSLTSIG Q0V8I4_BOVIN Q0V8I4_BOVIN PGDASPPIDLA-KKGPYGLSGLKRASASS---LRSVSAAEGNKSYSG----SIQSLTSIG RH10L_HUMAN RH10L_HUMAN ------------SK---------------------------------------------- YK021_HUMAN YK021_HUMAN PGDVSPPIDLV-KKEPYGLSGLKRASASS---LRSISAAEGNKSYSG----SIQSLTSVG MATCH CONSENSUS ????????????????????????????????????????????????????????????

Q4RIS0_TETNG Q4RIS0_TETNG FSRLNTETCLVVAARRAKRLE-LCTPVRRSTNPSCP------------------------ RHG26_XENLA RHG26_XENLA -------SSPVSVPRKAKALY-AC------------------------------------ RHG26_XENTR RHG26_XENTR ----------VSVPRKAKALY-AC------------------------------------ RHG26_CHICK RHG26_CHICK ----------SSPLRKARALY-AC------------------------------------ B7NZB3_RABIT B7NZB3_RABIT ------------------------------------------------------------ B9EJ96_MOUSE B9EJ96_MOUSE -----------TPFRKAKALY-AC------------------------------------ RHG26_MOUSE RHG26_MOUSE RPEEAVREDSSTPFRKAKALY-AC------------------------------------ Q5D035_HUMAN Q5D035_HUMAN ----------STPFRKAKALY-AC------------------------------------ RHG26_HUMAN RHG26_HUMAN RPEEAVHEDSSTPFRKAKALY-AC------------------------------------ Q1JPR9_DANRE Q1JPR9_DANRE --------EESVTLMKAKAVY-PC------------------------------------ Q4RKL2_TETNG Q4RKL2_TETNG -------TSDNVTSRKAKAVY-PC------------------------------------ Q2TAT2_XENLA Q2TAT2_XENLA -------SAESSAKRKAKAVY-PC------------------------------------ Q6DEE5_XENLA Q6DEE5_XENLA -------TSDTSAERKAKAVY-PC------------------------------------ RHG10_MOUSE RHG10_MOUSE ----------CVINRKARAVY-PC------------------------------------ RHG10_BOVIN RHG10_BOVIN ----------SIISRKARAVY-PC------------------------------------ B3KVP5_HUMAN B3KVP5_HUMAN -----------IRSRKARAVY-PC------------------------------------ B4E2W2_HUMAN B4E2W2_HUMAN ----------SIRSRKARAVY-PC------------------------------------ Q86T21_HUMAN Q86T21_HUMAN ----------SIRSRKARAVY-PC------------------------------------ RHG10_HUMAN RHG10_HUMAN ----------SIRSRKARAVY-PC------------------------------------ Q3KQX3_HUMAN Q3KQX3_HUMAN ----------SIRSRKARAVY-PC------------------------------------ Q8ND72_HUMAN Q8ND72_HUMAN ----------SIRSRKARAVY-PC------------------------------------ Q6IA27_HUMAN Q6IA27_HUMAN ----------SIRSRKARAVY-PC------------------------------------ Q9H7G7_HUMAN Q9H7G7_HUMAN ----------SIRSRKARAVY-PC------------------------------------ A2CEG8_DANRE A2CEG8_DANRE -------EKSSICRPPTRPPDPPSRLF--------------------------------- B1AV63_MOUSE B1AV63_MOUSE -------EKQTIIRPPVRPPDPPCRSITPQKPEPKP------------------------ OPHN1_MOUSE OPHN1_MOUSE -------EKQTIIRPPVRPPDPPCRSITPQKPEPKP------------------------ Q8C4C7_MOUSE Q8C4C7_MOUSE -------EKQTIIRPPVRPPDPPCRSITPQKPEPKP------------------------ Q6R7Z1_CAVPO Q6R7Z1_CAVPO -------EKPTIIRPPVRPPDPPCRAATPQKPEPKP------------------------ B4DIT2_HUMAN B4DIT2_HUMAN --------KPTIIRPPVRPPDPPCRAATPQKPEPKP------------------------ B9EIP8_HUMAN B9EIP8_HUMAN -------EKPTIIRPPVRPPDPPCRAATPQKPEPKP------------------------ OPHN1_PANTR OPHN1_PANTR -------EKPTIIRPPVRPPDPPCRAATPQKPEPKP------------------------ OPHN1_PONPY OPHN1_PONPY -------EKPTIIRPPVRPPDPPCRAATPQKPEPKP------------------------ OPHN1_HUMAN OPHN1_HUMAN -------EKPTIIRPPVRPPDPPCRAATPQKPEPKP------------------------ Q0P4U1_XENTR Q0P4U1_XENTR -------ERPVISRPPTRPPDPPCR-VALQKQEPRT------------------------ Q6PCK6_XENLA Q6PCK6_XENLA -------ERPVISRPPNRPPDPPCR-IALQKQEPRT------------------------ Q4RFN2_TETNG Q4RFN2_TETNG -------TTPRLSSAPKKAPH--CRSHL-------------------------------- Q4SFS4_TETNG Q4SFS4_TETNG QKMSSVPETETNSASPQQPRK-LYRTASSSSSSSSSLFTYQLSTSSSLTSLHISEGKSLK RH10L_DANRE RH10L_DANRE -------SIQSLVSRSQRDSL--------------------------------------- B2RQE8_MOUSE B2RQE8_MOUSE SK-----ESPKAIPNPELPPK-MCRRLRLDTASSNGYQRPG------------------- Q0V8I4_BOVIN Q0V8I4_BOVIN SK-----ETPKAAPNPDLPPK-MCRRLRLDTASSNGYQRPG------------------- RH10L_HUMAN RH10L_HUMAN -------ETPKASPNPDLPPK-MCRRLRLDTASSNG------------------------ YK021_HUMAN YK021_HUMAN SK-----ETPKASPNPDLPPK-MCRRLRLDTASSNGYQRPG------------------- MATCH CONSENSUS ???????????????????????C????????????????????????????????????

Q4RIS0_TETNG Q4RIS0_TETNG -----------------------------------SSPGPSSRTVSRRRTFRTPVRTQHT RHG26_XENLA RHG26_XENLA -------------------------------------------KAEHDSELSFSAGTVFE RHG26_XENTR RHG26_XENTR -------------------------------------------KAEHDSELSFSAGTVFD RHG26_CHICK RHG26_CHICK -------------------------------------------KAEHDSELSFTAGTVFD B7NZB3_RABIT B7NZB3_RABIT ------------------------------------------------------------ B9EJ96_MOUSE B9EJ96_MOUSE -------------------------------------------QAEHDSELSFTAGTVFD RHG26_MOUSE RHG26_MOUSE -------------------------------------------QAEHDSELSFTAGTVFD Q5D035_HUMAN Q5D035_HUMAN -------------------------------------------KAEHDSELSFTAGTVFD RHG26_HUMAN RHG26_HUMAN -------------------------------------------KAEHDSELSFTAGTVFD Q1JPR9_DANRE Q1JPR9_DANRE -------------------------------------------EAEHDSELSFQVGAIFH Q4RKL2_TETNG Q4RKL2_TETNG -------------------------------------------EAEHDSELSFQVGAIFN Q2TAT2_XENLA Q2TAT2_XENLA -------------------------------------------EAEHSSELSFEVGAVFE Q6DEE5_XENLA Q6DEE5_XENLA -------------------------------------------EAEHSTELSFEVGAVFE RHG10_MOUSE RHG10_MOUSE -------------------------------------------EAEHSSELSFEIGAIFE RHG10_BOVIN RHG10_BOVIN -------------------------------------------EAEHSSELSFEIGAIFE B3KVP5_HUMAN B3KVP5_HUMAN -------------------------------------------EAEHSSELSFEIGAIFE B4E2W2_HUMAN B4E2W2_HUMAN -------------------------------------------EAEHSSELSFEIGAIFE Q86T21_HUMAN Q86T21_HUMAN -------------------------------------------EAEHSSELSFEIGAIFE RHG10_HUMAN RHG10_HUMAN -------------------------------------------EAEHSSELSFEIGAIFE Q3KQX3_HUMAN Q3KQX3_HUMAN -------------------------------------------EAEHSSELSFEIGAIFE Q8ND72_HUMAN Q8ND72_HUMAN -------------------------------------------EAEHSSELSFEIGAIFE Q6IA27_HUMAN Q6IA27_HUMAN -------------------------------------------EAEHSSELSFEIGAIFE Q9H7G7_HUMAN Q9H7G7_HUMAN -------------------------------------------EAEHSSELSFEIGAIFE A2CEG8_DANRE A2CEG8_DANRE -------------------------------------------SKPPNEDTPPSYVASKT B1AV63_MOUSE B1AV63_MOUSE -----------------------------------------ETGSGNADEIPSSVVASRT OPHN1_MOUSE OPHN1_MOUSE -----------------------------------------ETGSGNADEIPSSVVASRT Q8C4C7_MOUSE Q8C4C7_MOUSE -----------------------------------------ETGSGNADEIPSSVVASRT Q6R7Z1_CAVPO Q6R7Z1_CAVPO -----------------------------------------DIVAGNAGEITSSVVASRT B4DIT2_HUMAN B4DIT2_HUMAN -----------------------------------------DIVAGNAGEITSSVVASRT B9EIP8_HUMAN B9EIP8_HUMAN -----------------------------------------DIVAGNAGEITSSVVASRT OPHN1_PANTR OPHN1_PANTR -----------------------------------------DIVAGNAGEITSSVVASRT OPHN1_PONPY OPHN1_PONPY -----------------------------------------DIVAGNAGEITSSVVASRT OPHN1_HUMAN OPHN1_HUMAN -----------------------------------------DIVAGNAGEITSSVVASRT Q0P4U1_XENTR Q0P4U1_XENTR -----------------------------------------DNSSLVKEDTPSSVVASRT Q6PCK6_XENLA Q6PCK6_XENLA -----------------------------------------EVSSLVKEDIP-SVVASRT Q4RFN2_TETNG Q4RFN2_TETNG -----------------------------------------SLAMMYHPDPSSMKSLHLP Q4SFS4_TETNG Q4SFS4_TETNG TSGETGIIGFLLSVGLPQRESSVFSSALDICSPGREAKALYSCEAEHSHELSFPQGALFS RH10L_DANRE RH10L_DANRE -------------------------------------------KSLHLPDLPPKDGMRFR B2RQE8_MOUSE B2RQE8_MOUSE ------------SVVAAKAQLFENAGSPKPVSSGRQAQAMYSCKAEHSHELSFPQGAIFS Q0V8I4_BOVIN Q0V8I4_BOVIN ------------SVVAAKAQLFENVGSVKPVSSGRQAKAMYSCKAEHSHELSFPQGALFS RH10L_HUMAN RH10L_HUMAN --------------------------------SFSQAKAMYSCKAEHSHELSFPQGAIFS YK021_HUMAN YK021_HUMAN ------------SVVAAKAQLFENVGSPKPVSSGRQAKAMYSCKAEHSHELSFPQGAIFS MATCH CONSENSUS ?????????????????????????????????????????????????E??????????

Q4RIS0_TETNG Q4RIS0_TETNG SFFLVCSPPSCASSSRLQGAWVAGGDSGRPDGTDPRKLRGDSIVQDRRRRPSWTDWSYDD RHG26_XENLA RHG26_XENLA NVCPSQEPG-----------WLEGTLNGKTG-----LIPENYVEFL-------------- RHG26_XENTR RHG26_XENTR NVYPSQEPG-----------WLEGILNGKTG-----LIPENYVEFL-------------- RHG26_CHICK RHG26_CHICK NVHPSQEPG-----------WLEGTLNGKTG-----LIPENYVEFL-------------- B7NZB3_RABIT B7NZB3_RABIT ------------------------------------------------------------ B9EJ96_MOUSE B9EJ96_MOUSE NVHPSQEPG-----------WLEGTLNGKTG-----LIPENYVEFL-------------- RHG26_MOUSE RHG26_MOUSE NVHPSQEPG-----------WLEGTLNGKTG-----LIPENYVEFL-------------- Q5D035_HUMAN Q5D035_HUMAN NVHPSQEPG-----------WLEGTLNGKTG-----LIPENYVEFL-------------- RHG26_HUMAN RHG26_HUMAN NVHPSQEPG-----------WLEGTLNGKTG-----LIPENYVEFL-------------- Q1JPR9_DANRE Q1JPR9_DANRE DVTLSREPG-----------WLEGVLEGKRG-----LIPENYVEIL-------------- Q4RKL2_TETNG Q4RKL2_TETNG AVTHSREPG-----------WLEGELNGKRG-----LIPENYVEIL-------------- Q2TAT2_XENLA Q2TAT2_XENLA DVHHSREPG-----------WLEGTLNGRRG-----LIPENYVHFL-------------- Q6DEE5_XENLA Q6DEE5_XENLA DVHYSREPG-----------WLEGTLNGRRG-----LIPENYVQFL-------------- RHG10_MOUSE RHG10_MOUSE DVQTSREPG-----------WLEGTLNGKRG-----LIPQNYVKLL-------------- RHG10_BOVIN RHG10_BOVIN DVQTSREPG-----------WLEGTLNGKRG-----LIPQNYVKLL-------------- B3KVP5_HUMAN B3KVP5_HUMAN DVQTSREPG-----------WLEGTLNGKRG-----LIPQNYVELL-------------- B4E2W2_HUMAN B4E2W2_HUMAN DVQTSREPG-----------WLEGTLNGKRG-----LIPQNYVKLL-------------- Q86T21_HUMAN Q86T21_HUMAN DVQTSREPG-----------WLEGTLNGKRG-----LIPQNYVKLL-------------- RHG10_HUMAN RHG10_HUMAN DVQTSREPG-----------WLEGTLNGKRG-----LIPQNYVKLL-------------- Q3KQX3_HUMAN Q3KQX3_HUMAN DVQTSREPG-----------WLEGTLNGKRG-----LIPQNYVKLL-------------- Q8ND72_HUMAN Q8ND72_HUMAN DVQTSREPG-----------WLEGTLNGKRG-----LIPQNYVKLL-------------- Q6IA27_HUMAN Q6IA27_HUMAN DVQTSREPG-----------WLEGTLNGKRG-----LIPQNYVKLL-------------- Q9H7G7_HUMAN Q9H7G7_HUMAN DVQTSREPG-----------WLEGTLNGKRG-----LIPQNYVKLL-------------- A2CEG8_DANRE A2CEG8_DANRE KFFENASRQ-----------MGSSSPNASPA-----ASRDENTK---------------- B1AV63_MOUSE B1AV63_MOUSE RFFETASRK-------------TGSSQG--------KLPGDES----------------- OPHN1_MOUSE OPHN1_MOUSE RFFETASRK-------------TGSSQG--------KLPGDES----------------- Q8C4C7_MOUSE Q8C4C7_MOUSE RFFETASRK-------------TGSSQG--------KLPGDES----------------- Q6R7Z1_CAVPO Q6R7Z1_CAVPO RFFETASRK-------------TGSSQG--------RLPGDES----------------- B4DIT2_HUMAN B4DIT2_HUMAN RFFETASRK-------------TGSSQG--------RLPGDES----------------- B9EIP8_HUMAN B9EIP8_HUMAN RFFETASRK-------------TGSSQG--------RLPGDES----------------- OPHN1_PANTR OPHN1_PANTR RFFETASRK-------------TGSSQG--------RLPGDES----------------- OPHN1_PONPY OPHN1_PONPY RFFETASRK-------------TGSSQG--------RLPGDES----------------- OPHN1_HUMAN OPHN1_HUMAN RFFETASRK-------------TGSSQG--------RLPGDES----------------- Q0P4U1_XENTR Q0P4U1_XENTR KFFENASRP-----------RVSPPSPPSRI-----LTEES------------------- Q6PCK6_XENLA Q6PCK6_XENLA KFFENASRP-----------RVSPPSPPSRI-----LTEES------------------- Q4RFN2_TETNG Q4RFN2_TETNG EVYPSVEPG-----------WLQATYEGRTG-----LIPENYVVFL-------------- Q4SFS4_TETNG Q4SFS4_TETNG NVYPSVEPG-----------WLQATYNGKTG-----LIPENYITYL-------------- RH10L_DANRE RH10L_DANRE DDSSASNGY---------------------------QRPGSV------------------ B2RQE8_MOUSE B2RQE8_MOUSE NVHPSVEPG-----------WLKATYEGRTG-----LVPENYVVFL-------------- Q0V8I4_BOVIN Q0V8I4_BOVIN NVYPSVEPG-----------WLKATYEGKTG-----LVPENYVVFL-------------- RH10L_HUMAN RH10L_HUMAN NVYPSVEPG-----------WLKATYEGKTG-----LVPENYVVFL-------------- YK021_HUMAN YK021_HUMAN NVYPSVEPG-----------WLKATYEGKTG-----LVPENYVVFL-------------- MATCH CONSENSUS ???????????????????????????G??????????P?????????????????????

Q4RIS0_TETNG Q4RIS0_TETNG GHV RHG26_XENLA RHG26_XENLA --- RHG26_XENTR RHG26_XENTR --- RHG26_CHICK RHG26_CHICK --- B7NZB3_RABIT B7NZB3_RABIT --- B9EJ96_MOUSE B9EJ96_MOUSE --- RHG26_MOUSE RHG26_MOUSE --- Q5D035_HUMAN Q5D035_HUMAN --- RHG26_HUMAN RHG26_HUMAN --- Q1JPR9_DANRE Q1JPR9_DANRE --- Q4RKL2_TETNG Q4RKL2_TETNG --- Q2TAT2_XENLA Q2TAT2_XENLA --- Q6DEE5_XENLA Q6DEE5_XENLA --- RHG10_MOUSE RHG10_MOUSE --- RHG10_BOVIN RHG10_BOVIN --- B3KVP5_HUMAN B3KVP5_HUMAN --- B4E2W2_HUMAN B4E2W2_HUMAN --- Q86T21_HUMAN Q86T21_HUMAN --- RHG10_HUMAN RHG10_HUMAN --- Q3KQX3_HUMAN Q3KQX3_HUMAN --- Q8ND72_HUMAN Q8ND72_HUMAN --- Q6IA27_HUMAN Q6IA27_HUMAN --- Q9H7G7_HUMAN Q9H7G7_HUMAN --- A2CEG8_DANRE A2CEG8_DANRE --- B1AV63_MOUSE B1AV63_MOUSE --- OPHN1_MOUSE OPHN1_MOUSE --- Q8C4C7_MOUSE Q8C4C7_MOUSE --- Q6R7Z1_CAVPO Q6R7Z1_CAVPO --- B4DIT2_HUMAN B4DIT2_HUMAN --- B9EIP8_HUMAN B9EIP8_HUMAN --- OPHN1_PANTR OPHN1_PANTR --- OPHN1_PONPY OPHN1_PONPY --- OPHN1_HUMAN OPHN1_HUMAN --- Q0P4U1_XENTR Q0P4U1_XENTR --- Q6PCK6_XENLA Q6PCK6_XENLA --- Q4RFN2_TETNG Q4RFN2_TETNG --- Q4SFS4_TETNG Q4SFS4_TETNG --- RH10L_DANRE RH10L_DANRE --- B2RQE8_MOUSE B2RQE8_MOUSE --- Q0V8I4_BOVIN Q0V8I4_BOVIN --- RH10L_HUMAN RH10L_HUMAN --- YK021_HUMAN YK021_HUMAN --- MATCH CONSENSUS ???


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