Alignment of the gene Family HBG080238 of HOVERGEN

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Isoforms are ON
A2AEG2_MOUSE A2AEG2_MOUSE RMAQSNMPHKSDVLSQDELRKKLYQTFKDRGVLDTLQTQLRNQLIHELMHPVLSGEVKPP OFD1_MOUSE OFD1_MOUSE -MAQSNMPHKSDVLSQDELRKKLYQTFKDRGVLDTLQTQLRNQLIHELMHPVLSGEVKPP B4DLQ3_HUMAN B4DLQ3_HUMAN ------------------------------------------------------------ A6NF31_HUMAN A6NF31_HUMAN ------------------------------------------------------------ A8K2T9_HUMAN A8K2T9_HUMAN MMAQSNMFTVADVLSQDELRKKLYQTFKDRGILDTLKTQLRNQLIHELMHPVLSGELQPR OFD1_HUMAN OFD1_HUMAN MMAQSNMFTVADVLSQDELRKKLYQTFKDRGILDTLKTQLRNQLIHELMHPVLSGELQPR MATCH CONSENSUS ????????????????????????????????????????????????????????????

A2AEG2_MOUSE A2AEG2_MOUSE SISVEGSALLIGASNSLVADHLQRCGYEYSLSVFFPESGLAKEKIFTMQDLLQLIRINPS OFD1_MOUSE OFD1_MOUSE SISVEGSALLIGASNSLVADHLQRCGYEYSLSVFFPESGLAKEKIFTMQDLLQLIRINPS B4DLQ3_HUMAN B4DLQ3_HUMAN ------------------------------------------------------------ A6NF31_HUMAN A6NF31_HUMAN ------------------------------------------------------------ A8K2T9_HUMAN A8K2T9_HUMAN SISVEGSSLLIGASNSLVADHLQRCGYEYSLSVFFPESGLAKEKVFTMQDLLQLIKINPT OFD1_HUMAN OFD1_HUMAN SISVEGSSLLIGASNSLVADHLQRCGYEYSLSVFFPESGLAKEKVFTMQDLLQLIKINPT MATCH CONSENSUS ????????????????????????????????????????????????????????????

A2AEG2_MOUSE A2AEG2_MOUSE SSLYKSLISGFDKENKKGFLMSFLKELAEYYQAKESCDAETQTSTTFPSQVSLAEKFQLI OFD1_MOUSE OFD1_MOUSE SSLYKSLISGFDKENKKGFLMSFLKELAEYYQAKESCDAETQTSTTFPSQVSLAEKFQLI B4DLQ3_HUMAN B4DLQ3_HUMAN ------------------------------------------------------------ A6NF31_HUMAN A6NF31_HUMAN --------------------MHFLKELAEYHQAKESCNMETQTSSTF-NRDSLAEKLQLI A8K2T9_HUMAN A8K2T9_HUMAN SSLYKSLVSGSDKENQKGFLMHFLKELAEYHQAKESCNMETQTSSTF-NRDSLAEKLQLI OFD1_HUMAN OFD1_HUMAN SSLYKSLVSGSDKENQKGFLMHFLKELAEYHQAKESCNMETQTSSTF-NRDSLAEKLQLI MATCH CONSENSUS ????????????????????M?FLKELAEY?QAKESC??ETQTS?TF????SLAEK?QLI

A2AEG2_MOUSE A2AEG2_MOUSE DAQFADGFPHRSKLESLETKLNEYKKEVQHQLQVEMCHKLKYFREAEITKVKMEERRKYE OFD1_MOUSE OFD1_MOUSE DAQFADGFPHRSKLESLETKLNEYKKEVQHQLQVEMCHKLKYFREAEITKVKMEERRKYE B4DLQ3_HUMAN B4DLQ3_HUMAN ------------------------------------------------------------ A6NF31_HUMAN A6NF31_HUMAN DDQFADAYPQRIKFESLEIKLNEYKREIEEQLRAEMCQKLKFFKDTEIAKIKMEAKKKYE A8K2T9_HUMAN A8K2T9_HUMAN DDQFADAYPQRIKFESLEIKLNEYKREIEEQLRAEMCQKLKFFKDTEIAKIKMEAKKKYE OFD1_HUMAN OFD1_HUMAN DDQFADAYPQRIKFESLEIKLNEYKREIEEQLRAEMCQKLKFFKDTEIAKIKMEAKKKYE MATCH CONSENSUS D?QFAD??P?R?K?ESLE?KLNEYK?E???QL??EMC?KLK?F???EI?K?KME???KYE

A2AEG2_MOUSE A2AEG2_MOUSE KELAEFQNEFERTCQAKNEALISQEKNSLERIKKHREMESKEIYAQRQLLLNDIALLRGR OFD1_MOUSE OFD1_MOUSE KELAEFQNEFERTCQAKNEALISQEKNSLERIKKHREMESKEIYAQRQLLLNDIALLRGR B4DLQ3_HUMAN B4DLQ3_HUMAN -----------------------------------------------------MDLLRGR A6NF31_HUMAN A6NF31_HUMAN KELTMFQNDFEKACQAKSEALVLREKSTLERIHKHQEIETKEIYAQRQLLLKDMDLLRGR A8K2T9_HUMAN A8K2T9_HUMAN KELTMFQNDFEKACQAKSEALVLREKSTLERIHKHQEIETKEIYAQRQLLLKDMDLLRGR OFD1_HUMAN OFD1_HUMAN KELTMFQNDFEKACQAKSEALVLREKSTLERIHKHQEIETKEIYAQRQLLLKDMDLLRGR MATCH : ***** CONSENSUS KEL??FQN?FE??CQAK?EAL???EK??LERI?KH?E?E?KEIYAQRQLLL?D??LLRGR

A2AEG2_MOUSE A2AEG2_MOUSE EAELKERIETFELTQKLQEEKIKSEAEALERREQNLKNIEDTYDQKLKTELLKYQLELKD OFD1_MOUSE OFD1_MOUSE EAELKERIETFELTQKLQEEKIKSEAEALERREQNLKNIEDTYDQKLKTELLKYQLELKD B4DLQ3_HUMAN B4DLQ3_HUMAN EAELKQRVEAFEL----------------------------------------YQLELKD A6NF31_HUMAN A6NF31_HUMAN EAELKQRVEAFELNQKLQEEKHKSITEALRRQEQNIKSFEETYDRKLKNELLKYQLELKD A8K2T9_HUMAN A8K2T9_HUMAN EAELKQRVEAFELNQKLQEEKHKSITEALRRQEQNIKSFEETYDRKLKNELLKYQLELKD OFD1_HUMAN OFD1_HUMAN EAELKQRVEAFELNQKLQEEKHKSITEALRRQEQNIKSFEETYDRKLKNELLKYQLELKD MATCH *****:*:*:*** ******* CONSENSUS EAELK?R?E?FEL?QKLQEEK?KS??EAL?R?EQN?K??E?TYD?KLK?ELLKYQLELKD

A2AEG2_MOUSE A2AEG2_MOUSE DYITRTNKLLEEERKNKEKTIHLQEELTVINSKKEELSKSVKHMKEVELELESVKAQFLA OFD1_MOUSE OFD1_MOUSE DYITRTNKLLEEERKNKEKTIHLQEELTVINSKKEELSKSVKHMKEVELELESVKAQFLA B4DLQ3_HUMAN B4DLQ3_HUMAN DYIIRTNRLIEDERKNKEKAVHLQEELIAINSKKEELNQSVNRVKELELELESVKAQSLA A6NF31_HUMAN A6NF31_HUMAN DYIIRTNRLIEDERKNKEKAVHLQEELIAINSKKEELNQSVNRVKELELELESVKAQSLA A8K2T9_HUMAN A8K2T9_HUMAN DYIIRTNRLIEDERKNKEKAVHLQEELIAINSKKEELNQSVNRVKELELELESVKAQSLA OFD1_HUMAN OFD1_HUMAN DYIIRTNRLIEDERKNKEKAVHLQEELIAINSKKEELNQSVNRVKELELELESVKAQSLA MATCH *** ***:*:*:*******::****** .********.:**:::**:********** ** CONSENSUS DYI?RTN?L?E?ERKNKEK??HLQEEL??INSKKEEL??SV???KE?ELELESVKAQ?LA

A2AEG2_MOUSE A2AEG2_MOUSE ISKQNHLLNEKVREMSDYSQLKEEKVELQAQNKLLKLQLEETRNENLRLLDRITQPPPEL OFD1_MOUSE OFD1_MOUSE ISKQNHLLNEKVREMSDYSQLKEEKVELQAQNKLLKLQLEETRNENLRLLDRITQPPPEL B4DLQ3_HUMAN B4DLQ3_HUMAN ITKQNHMLNEKVKEMSDYSLLKEEKLELLAQNKLLKQQLEESRNENLRLLNRLAQPAPEL A6NF31_HUMAN A6NF31_HUMAN ITKQNHMLNEKVKEMSDYSLLKEEKLELLAQNKLLKQQLEESRNENLRLLNRLAQPAPEL A8K2T9_HUMAN A8K2T9_HUMAN ITKQNHMLNEKVKEMSDYSLLKEEKLELLAQNKLLKQQLEESRNENLRLLNRLAQPAPEL OFD1_HUMAN OFD1_HUMAN ITKQNHMLNEKVKEMSDYSLLKEEKLELLAQNKLLKQQLEESRNENLRLLNRLAQPAPEL MATCH *:****:*****:****** *****:** ******* ****:********:*::**.*** CONSENSUS I?KQNH?LNEKV?EMSDYS?LKEEK?EL?AQNKLLK?QLEE?RNENLRLL?R??QP?PEL

A2AEG2_MOUSE A2AEG2_MOUSE VIFQKELQKTEKAMELEHKDFETHRQALEKQLQSEIENSAQLRTQIAEYDASVKRLTVQV OFD1_MOUSE OFD1_MOUSE VIFQKELQKTEKAMELEHKDFETHRQALEKQLQSEIENSAQLRTQIAEYDASVKRLTVQV B4DLQ3_HUMAN B4DLQ3_HUMAN AVFQKELRKAEKAIVVEHEEFESCRQALHKQLQDEIEHSAQLKAQILGYKASVKSLTTQV A6NF31_HUMAN A6NF31_HUMAN AVFQKELRKAEKAIVVEHEEFESCRQALHKQLQDEIEHSAQLKAQILGYKASVKSLTTQV A8K2T9_HUMAN A8K2T9_HUMAN AVFQKELRKAEKAIVVEHEEFESCRQALHKQLQDEIEHSAQLKAQILGYKASVKSLTTQV OFD1_HUMAN OFD1_HUMAN AVFQKELRKAEKAIVVEHEEFESCRQALHKQLQDEIEHSAQLKAQILGYKASVKSLTTQV MATCH .:*****:*:***: :**::**: ****.****.***:****::** *.**** **.** CONSENSUS ??FQKEL?K?EKA???EH??FE??RQAL?KQLQ?EIE?SAQL??QI??Y?ASVK?LT?QV

A2AEG2_MOUSE A2AEG2_MOUSE AELKSQLKQTQIALENEVYRNPKHSLIHSLSGLLLSGKMAPHSEDKSGDFLNVPLEQNKV OFD1_MOUSE OFD1_MOUSE AELKSQLKQTQIALENEVYRNPKHSLIHSLSGLLLSGKMAPHSEDKSGDFLNVPLEQNKV B4DLQ3_HUMAN B4DLQ3_HUMAN ADLKLQLKQTQTALENEVYCNPKQSVIDRSVNGLINGNVVPCNGEISGDFLNNPFKQENV A6NF31_HUMAN A6NF31_HUMAN ADLKLQLKQTQTALENEVYCNPKQSVIDRSVNGLINGNVVPCNGEISGDFLNNPFKQENV A8K2T9_HUMAN A8K2T9_HUMAN ADLKLQLKQTQTALENEVYCNPKQSVIDRSVNGLINGNVVPCNGEISGDFLNNPFKQENV OFD1_HUMAN OFD1_HUMAN ADLKLQLKQTQTALENEVYCNPKQSVIDRSVNGLINGNVVPCNGEISGDFLNNPFKQENV MATCH *:** ****** ******* ***:*:*. . *:.*::.* . : ****** *::*::* CONSENSUS A?LK?QLKQTQ?ALENEVY?NPK?S?I??????L??G???P?????SGDFLN?P??Q??V

A2AEG2_MOUSE A2AEG2_MOUSE IAGAVMSRVPPYVNTATEASSPESDFEFIASSTKAKVRELEQEAERLEKAFRTYYQRATQ OFD1_MOUSE OFD1_MOUSE IAGAVMSRVPPYVNTATEASSPESDFEFIASSTKAKVRELEQEAERLEKAFRTYYQRATQ B4DLQ3_HUMAN B4DLQ3_HUMAN LARMVASRITNYPTAWVEGSSPDSDLEFVA-NTKARVKELQQEAERLEKAFRSYHRRVIK A6NF31_HUMAN A6NF31_HUMAN LARMVASRITNYPTAWVEGSSPDSDLEFVA-NTKARVKELQQEAERLEKAFRSYHRRVIK A8K2T9_HUMAN A8K2T9_HUMAN LARMVASRITNYPTAWVEGSSPDSDLEFVA-NTKARVKELQQEAERLEKAFRSYHRRVIK OFD1_HUMAN OFD1_HUMAN LARMVASRITNYPTAWVEGSSPDSDLEFVA-NTKARVKELQQEAERLEKAFRSYHRRVIK MATCH :* * **:. * .: .*.***:**:**:* .***:*:**:***********:*::*. : CONSENSUS ?A??V?SR???Y?????E?SSP?SD?EF?A??TKA?V?EL?QEAERLEKAFR?Y??R???

A2AEG2_MOUSE A2AEG2_MOUSE NPSTSPQPAKSPPSVNSVAALRSIASSSMDRPVSAEDRVVSEQPLGDMLKEEMSDMSKAF OFD1_MOUSE OFD1_MOUSE NPSTSPQPAKSPPSVNSVAALRSIASSSMDRPVSAEDRVVSEQPLGDMLKEEMSDMSKAF B4DLQ3_HUMAN B4DLQ3_HUMAN NSAKSPLAAKSPPSLHLLEAFKNITSSSPERHIFGEDRVVSEQPQVGTL-EERNDVVEAL A6NF31_HUMAN A6NF31_HUMAN NSAKSPLAAKSPPSLHLLEAFKNITSSSPERHIFGEDRVVSEQPQVGTL-EERNDVVEAL A8K2T9_HUMAN A8K2T9_HUMAN NSAKSPLAAKSPPSLHLLEAFKNITSSSPERHIFGEDRVVSEQPQVGTL-EERNDVVEAL OFD1_HUMAN OFD1_HUMAN NSAKSPLAAKSPPSLHLLEAFKNITSSSPERHIFGEDRVVSEQPQVGTL-EERNDVVEAL MATCH *.:.** .******:: : *::.*:*** :* : .********* . * ** .*: :*: CONSENSUS N???SP??AKSPPS?????A???I?SSS??R????EDRVVSEQP????L?EE??D???A?

A2AEG2_MOUSE A2AEG2_MOUSE MGSVVSRPRRTSSSTRLSSTPHPKSRRSLDNEMYLEGLGRLHMTSSSPLLDRVSASPAAS OFD1_MOUSE OFD1_MOUSE MGSVVSRPRRTSSSTRLSSTPHPKSRRSLDNEMYLEGLGRLHMTSSSPLLDRVSASPAAS B4DLQ3_HUMAN B4DLQ3_HUMAN TGSAASRLRGGTSSRRLSSTPLPKAKRSLESEMYLEGLGRSHI---------------AS A6NF31_HUMAN A6NF31_HUMAN TGSAASRLRGGTSSRRLSSTPLPKAKRSLESEMYLEGLGRSHI---------------AS A8K2T9_HUMAN A8K2T9_HUMAN TGSAASRLRGGTSSRRLSSTPLPKAKRSLESEMYLEGLGRSHI---------------AS OFD1_HUMAN OFD1_HUMAN TGSAASRLRGGTSSRRLSSTPLPKAKRSLESEMYLEGLGRSHI---------------AS MATCH **..** * :** ****** **::***:.********* *: ** CONSENSUS ?GS??SR?R???SS?RLSSTP?PK??RSL??EMYLEGLGR?H????????????????AS

A2AEG2_MOUSE A2AEG2_MOUSE PSPCPERTAQASPVPSRHSF-----SGLPEQNACLYQRQTETQDKSELSNVDKQSLKD-E OFD1_MOUSE OFD1_MOUSE PSPCPERTAQASPVPSRHSF-----SGLPEQNACLYQRQTETQDKSELSNVDKQSLKD-E B4DLQ3_HUMAN B4DLQ3_HUMAN PSPCPDRMPLPSPTESRHSLSIPPVSSPPEQKVGLYRRQTELQDKSEFSDVDKLAFKDNE A6NF31_HUMAN A6NF31_HUMAN PSPCPDRMPLPSPTESRHSLSIPPVSSPPEQKVGLYRRQTELQDKSEFSDVDKLAFKDNE A8K2T9_HUMAN A8K2T9_HUMAN PSPCPDRMPLPSPTESRHSLSIPPVSSPPEQKVGLYRRQTELQDKSEFSDVDKLAFKDNE OFD1_HUMAN OFD1_HUMAN PSPCPDRMPLPSPTESRHSLSIPPVSSPPEQKVGLYRRQTELQDKSEFSDVDKLAFKDNE MATCH *****:* . .**. ****: *. ***:. **:**** *****:*:*** ::** * CONSENSUS PSPCP?R????SP??SRHS??????S??PEQ???LY?RQTE?QDKSE?S?VDK???KD?E

A2AEG2_MOUSE A2AEG2_MOUSE KFEPPFRW--NKTEQFEAEGLHPAGDMPGIDFAVATQSSRLISYDYPSAVQSQTGEQDEQ OFD1_MOUSE OFD1_MOUSE KFEPPFRW--NKTEQFEAEGLHPAGDMPGIDFAVATQSSRLISYDYPSAVQSQTGEQDEQ B4DLQ3_HUMAN B4DLQ3_HUMAN EFESSFESAGNMPRQLEMGGLSPAGDMSHVDAAAAAVP---LSYQHPSVDQKQIEEQKEE A6NF31_HUMAN A6NF31_HUMAN EFESSFESAGNMPRQLEMGGLSPAGDMSHVDAAAAAVP---LSYQHPSVDQKQIEEQKEE A8K2T9_HUMAN A8K2T9_HUMAN EFESSFESAGNMPRQLEMGGLSPAGDMSHVDAAAAAVP---LSYQHPSVDQKQIEEQKEE OFD1_HUMAN OFD1_HUMAN EFESSFESAGNMPRQLEMGGLSPAGDMSHVDAAAAAVP---LSYQHPSVDQKQIEEQKEE MATCH :**..*. * ..*:* ** *****. :* *.*: . :**::**. *.* **.*: CONSENSUS ?FE??F????N???Q?E??GL?PAGDM???D?A?A???????SY??PS??Q?Q??EQ?E?

A2AEG2_MOUSE A2AEG2_MOUSE E-LWELHMKERRQREEQRHNERQEALERERRELGKLEQERRMIEESLK------MEMEEE OFD1_MOUSE OFD1_MOUSE E-LWELHMKERRQREEQRHNERQEALERERRELGKLEQERRMIEESLK------MEMEEE B4DLQ3_HUMAN B4DLQ3_HUMAN EKIREQQVKERRQREERRQSNLQEVLERERRELEKLYQERKMIEESLKIKIKKELEMENE A6NF31_HUMAN A6NF31_HUMAN EKIREQQVKERRQREERRQSNLQEVLERERRELEKLYQERKMIEESLKIKIKKELEMENE A8K2T9_HUMAN A8K2T9_HUMAN EKIREQQVKERRQREERRQSNLQEVLERERRELEKLYQER-MIEESLKIKIKKELEMENE OFD1_HUMAN OFD1_HUMAN EKIREQQVKERRQREERRQSNLQEVLERERRELEKLYQERKMIEESLKIKIKKELEMENE MATCH * : * ::********:*:.: **.******** ** *** ******* :***:* CONSENSUS E???E???KERRQREE?R????QE?LERERREL?KL?QER?MIEESLK???????EME?E

A2AEG2_MOUSE A2AEG2_MOUSE LEKSVQDQKDKSAHCENTLEKYMKIIQQRQEESNADKSSKKSGKECSLVDMMMPSDKDES OFD1_MOUSE OFD1_MOUSE LEKSVQDQKDKSAHCENTLEKYMKIIQQRQEESNADKSSKKSGKECSLVDMMMPSDKDES B4DLQ3_HUMAN B4DLQ3_HUMAN LEMSNQEIKDKSAHSENPLEKYMKIIQQEQDQESADKSSKKMVQEGSLVDTLQSSDKVES A6NF31_HUMAN A6NF31_HUMAN LEMSNQEIKDKSAHSENPLEKYMKIIQQEQDQESADKSSKKMVQEGSLVDTLQSSDKVES A8K2T9_HUMAN A8K2T9_HUMAN LEMSNQEIKDKSAHSENPLEKYMKIIQQEQDQESADKSSKKMVQEGSLVDTLQSSDKVES OFD1_HUMAN OFD1_HUMAN LEMSNQEIKDKSAHSENPLEKYMKIIQQEQDQESADKSSKKMVQEGSLVDTLQSSDKVES MATCH ** * *: ******.**.**********.*::..******* :* **** : .*** ** CONSENSUS LE?S?Q??KDKSAH?EN?LEKYMKIIQQ?Q????ADKSSKK???E?SLVD????SDK?ES

A2AEG2_MOUSE A2AEG2_MOUSE SPGFSHEEPDDMW OFD1_MOUSE OFD1_MOUSE SPGFSHEEPDDMW B4DLQ3_HUMAN B4DLQ3_HUMAN LTGFSHEELDDSW A6NF31_HUMAN A6NF31_HUMAN LTGFSHEELDDSW A8K2T9_HUMAN A8K2T9_HUMAN LTGFSHEELDDSW OFD1_HUMAN OFD1_HUMAN LTGFSHEELDDSW MATCH .****** ** * CONSENSUS ??GFSHEE?DD?W


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