Alignment of the gene Family HBG080243 of HOVERGEN

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Isoforms are ON
A7MC52_XENTR A7MC52_XENTR AQALSEEEFQRMQAQLLELRTQNYQLSDGLRKNSQELSSLRQKHGTLEKEFGKAQKALSK B2GU72_XENTR B2GU72_XENTR AQALSEEEFQRMQAQLLELRTQNYQLSDGLRKNSQELSSLRQKHGTLEKEFGKAQKALSK Q4T6K8_TETNG Q4T6K8_TETNG ------------------------------------------------------------ B0UYE9_DANRE B0UYE9_DANRE AQALSEEEFHRMQAQLLELRTQNYQLSDELRKNTAELNSVRQKISNLEKDYVKAQKALNK A8K7Z3_HUMAN A8K7Z3_HUMAN AQALSEEEFQRMQAQLLELRTNNYQLSDELRKNGVELTSLRQKVAYLDKEFSKAQKALSK B1B0M1_HUMAN B1B0M1_HUMAN AQALSEEEFQRMQAQLLELRTNNYQLSDELRKNGVELTSLRQKVAYLDKEFSKAQ----- GRAP1_HUMAN GRAP1_HUMAN AQALSEEEFQRMQAQLLELRTNNYQLSDELRKNGVELTSLRQKVAYLDKEFSKAQKALSK GRAP1_RAT GRAP1_RAT AQALSEEEFQRMQTQLLELRTNNYQLSDELRKNGVELSSLRQKVAYLDKEFSKAQKALSK Q3T9D9_MOUSE Q3T9D9_MOUSE AQALSEEEFQRMQTQLLELRTNNYQLSDELRKNGVELSSLRQKVAYLDKEFSKAQ----- Q3TZ55_MOUSE Q3TZ55_MOUSE AQALSEEEFQRMQTQLLELRTNNYQLSDELRKNGVELSSLRQKVAYLDKEFSKAQ----- A2AEW6_MOUSE A2AEW6_MOUSE AQALSEEEFQRMQTQLLELRTNNYQLSDELRKNGVELSSLRQKVAYLDKEFSKAQ----- A2AEW8_MOUSE A2AEW8_MOUSE AQALSEEEFQRMQTQLLELRTNNYQLSDELRKNGVELSSLRQKVAYLDKEFSKAQKALSK GRAP1_MOUSE GRAP1_MOUSE AQALSEEEFQRMQTQLLELRTNNYQLSDELRKNGVELSSLRQKVAYLDKEFSKAQKALSK A2AEW5_MOUSE A2AEW5_MOUSE AQALSEEEFQRMQTQLLELRTNNYQLSDELRKNGVELSSLRQKVAYLDKEFSKAQ----- A2AEW9_MOUSE A2AEW9_MOUSE AQALSEEEFQRMQTQLLELRTNNYQLSDELRKNGVELSSLRQKVAYLDKEFSKAQ----- MATCH CONSENSUS AQALSEEEFQRMQ?QLLELRT?NYQLSDELRKN??EL?SLRQK???L?KEF?KAQ?????

A7MC52_XENTR A7MC52_XENTR SKKAQEVEALLGENEMLQGKLHSQEDDFRLQNTTLMQELSKLCSQIEQLEAENARVKA-- B2GU72_XENTR B2GU72_XENTR SKKAQEVEALLGENEMLQGKLHSQEDDFRLQNTTLMQELSKLCSQIEQLEAENARVKA-- Q4T6K8_TETNG Q4T6K8_TETNG ------------------------------------------------------------ B0UYE9_DANRE B0UYE9_DANRE SKKAQEVDALINENKMLQGKLHSQEDDFRLQNSTLMQELSKLCSQIELLESENQGLRDGK A8K7Z3_HUMAN A8K7Z3_HUMAN SKKAQEVEVLLSENEMLQAKLHSQEEDFRLQNSTLMAEFSKLCSQMEQLEQENQQLKEG- B1B0M1_HUMAN B1B0M1_HUMAN ----------------------------------------KLCSQMEQLEQENQQLKEG- GRAP1_HUMAN GRAP1_HUMAN SKKAQEVEVLLSENEMLQAKLHSQEEDFRLQNSTLMAEFSKLCSQMEQLEQENQQLKEG- GRAP1_RAT GRAP1_RAT SKKAQEVEVLLSEKEMLQAKLHSQEEDFRLQNSTLMAEFSKLCSQLEQLELENRQLKEG- Q3T9D9_MOUSE Q3T9D9_MOUSE ----------------------------------------KLCSQLEQLELENRQLKEG- Q3TZ55_MOUSE Q3TZ55_MOUSE ----------------------------------------KLCSQLEQLELENRQLKEG- A2AEW6_MOUSE A2AEW6_MOUSE ----------------------------------------KLCSQLEQLELENRQLKEG- A2AEW8_MOUSE A2AEW8_MOUSE SKKAQEVEVLLSENEMLQAKLHSQEEDFRLQNSTLMAEFSKLCSQLEQLELENRQLKEG- GRAP1_MOUSE GRAP1_MOUSE SKKAQEVEVLLSENEMLQAKLHSQEEDFRLQNSTLMAEFSKLCSQLEQLELENRQLKEG- A2AEW5_MOUSE A2AEW5_MOUSE ----------------------------------------KLCSQLEQLELENRQLKEG- A2AEW9_MOUSE A2AEW9_MOUSE ----------------------------------------KLCSQLEQLELENRQLKEG- MATCH CONSENSUS ????????????????????????????????????????KLCSQ?EQLE?EN??LK?G?

A7MC52_XENTR A7MC52_XENTR ---APSG----SG---EEDVQRLRAENSALQKRIATLQE----FHEKEVGSRRCQESEAN B2GU72_XENTR B2GU72_XENTR ---APSG----SG---EEDVQRLRAENSALQKRIATLQE----FHEKEVGSRRCQESEAN Q4T6K8_TETNG Q4T6K8_TETNG ------------------------------------------------------------ B0UYE9_DANRE B0UYE9_DANRE GLEKPAC--SPASAPVDAELLRLQAENSALQKKLTALQEIADGNGGKAAL-----VDGST A8K7Z3_HUMAN A8K7Z3_HUMAN ---AAGAGVAQAGPLVDGELLRLQAENTALQKNVAALQE----RYGKEAG---------- B1B0M1_HUMAN B1B0M1_HUMAN ---AAGAGVAQAGPLVDGELLRLQAENTALQKNVAALQE----RYGKEAG---------- GRAP1_HUMAN GRAP1_HUMAN ---AAGAGVAQAGPLVDGELLRLQAENTALQKNVAALQE----RYGKEAG---------- GRAP1_RAT GRAP1_RAT ---VPGA----AGPHVDGELLRLQAENTALQKNMAALQE----RYGKEAV---------- Q3T9D9_MOUSE Q3T9D9_MOUSE ---VPGA----AGAHVDGELLRLQAENTALQKNMAALQE----RYGKEAV---------- Q3TZ55_MOUSE Q3TZ55_MOUSE ---VPGA----AGAHVDGELLRLQAENTALQKNMAALQE----RYGKEAV---------- A2AEW6_MOUSE A2AEW6_MOUSE ---VPGA----AGAHVDGELLRLQAENTALQKNMAALQE----RYGKEAV---------- A2AEW8_MOUSE A2AEW8_MOUSE ---VPGA----AGAHVDGELLRLQAENTALQKNMAALQE----RYGKEAV---------- GRAP1_MOUSE GRAP1_MOUSE ---VPGA----AGAHVDGELLRLQAENTALQKNMAALQE----RYGKEAV---------- A2AEW5_MOUSE A2AEW5_MOUSE ---VPGA----AGAHVDGELLRLQAENTALQKNMAALQE----RYGKEAV---------- A2AEW9_MOUSE A2AEW9_MOUSE ---VPGA----AGAHVDGELLRLQAENTALQKNMAALQE----RYGKEAV---------- MATCH CONSENSUS ???????????AG??VD?ELLRLQAEN?ALQK??AALQE??????GKEA???????????

A7MC52_XENTR A7MC52_XENTR GHGATHREDGAGGSHPLVQTDGQADAKQDGLGACSWEPITDDLQGFQLKLETQTEENRLL B2GU72_XENTR B2GU72_XENTR GHGATHREDGAGGSHPLVQTDGQADAKQDGLGACSWEPITDDLQGFQLKLETQTEENRLL Q4T6K8_TETNG Q4T6K8_TETNG --------------------------------------------ELEMALSTEQEEKRLL B0UYE9_DANRE B0UYE9_DANRE GTNGVQSDASGHSNDSSASGNDQTD-QADLQ-SVKAEKRENEVREVALKLQTEMEEKCLL A8K7Z3_HUMAN A8K7Z3_HUMAN --------------KFSAVSEGQGDPPGGPA-PTVLAPMP--LAEVELKWEMEKEEKRLL B1B0M1_HUMAN B1B0M1_HUMAN --------------KFSAVSEGQGDPPGGPA-PTVLAPMP--LAEVELKWEMEKEEKRLL GRAP1_HUMAN GRAP1_HUMAN --------------KFSAVSEGQGDPPGGPA-PTVLAPMP--LAEVELKWEMEKEEKRLL GRAP1_RAT GRAP1_RAT --------------RPSAVSEGQGDPPGDVL-PISLSPMP--LAEVELKWEMEREEKKLL Q3T9D9_MOUSE Q3T9D9_MOUSE --------------RPSAVGEGQGDPPGDVL-PTPLAPMP--LAEVELKWEMEREEKKLL Q3TZ55_MOUSE Q3TZ55_MOUSE --------------RPSAVGEGQGDPPGDVL-PTPLAPMP--LAEVELKWEMEREEKKLL A2AEW6_MOUSE A2AEW6_MOUSE --------------RPSAVGEGQGDPPGDVL-PTPLAPMP--LAEVELKWEMEREEKKLL A2AEW8_MOUSE A2AEW8_MOUSE --------------RPSAVGEGQGDPPGDVL-PTPLAPMP--LAEVELKWEMEREEKKLL GRAP1_MOUSE GRAP1_MOUSE --------------RPSAVGEGQGDPPGDVL-PTPLAPMP--LAEVELKWEMEREEKKLL A2AEW5_MOUSE A2AEW5_MOUSE --------------RPSAVGEGQGDPPGDVL-PTPLAPMP--LAEVELKWEMEREEKKLL A2AEW9_MOUSE A2AEW9_MOUSE --------------RPSAVGEGQGDPPGDVL-PTPLAPMP--LAEVELKWEMEREEKKLL MATCH . : . : **: ** CONSENSUS ????????????????SA???GQ?D????????????P????L?EVELK?E?E?EEK?LL

A7MC52_XENTR A7MC52_XENTR RGQIQSL----QEQMAKLQEEQSKTAEKLKKKHDSFLQLQGEKEALYNDSRTKIEEIQQK B2GU72_XENTR B2GU72_XENTR RGQIQSL----QEQMAKLQEEQSKTAEKLKKKHDSFLQLQGEKEALYNDSRTKIEEIQQK Q4T6K8_TETNG Q4T6K8_TETNG KEQMQHLETSKQAESTRLQEEIVKLGEKLKKKQESFQRLQAEKEVLYNDSRTKIDEINQR B0UYE9_DANRE B0UYE9_DANRE REQLQTLEISKQAEITKLQEESAKLTDKLKKKQESFQRLQVEKEVLYNDSRTKIDEIQQR A8K7Z3_HUMAN A8K7Z3_HUMAN WEQLQGLESSKQAETSRLQEELAKLSEKLKKKQESFCRLQTEKETLFNDSRNKIEELQQR B1B0M1_HUMAN B1B0M1_HUMAN WEQLQGLESSKQAETSRLQEELAKLSEKLKKKQESFCRLQTEKETLFNDSRNKIEELQQR GRAP1_HUMAN GRAP1_HUMAN WEQLQGLESSKQAETSRLQEELAKLSEKLKKKQESFCRLQTEKETLFNDSRNKIEELQQR GRAP1_RAT GRAP1_RAT WEQLQGLESSKQAETSRLQEELAKLSEKLKKKQESFCRLQTEKETLFNDSRNKIEELQQR Q3T9D9_MOUSE Q3T9D9_MOUSE WEQLQGLESSKQAETSRLQEELAKLSEKLKKKQESFCRLQTEKETLFNDSRNKIEELQQR Q3TZ55_MOUSE Q3TZ55_MOUSE WEQLQGLE----------------LSEKLKKKQESFCRLQTEKETLFNDSRNKIEELQQR A2AEW6_MOUSE A2AEW6_MOUSE WEQLQGLE----------------LSEKLKKKQESFCRLQTEKETLFNDSRNKIEELQQR A2AEW8_MOUSE A2AEW8_MOUSE WEQLQGLESSKQAETSRLQEELAKLSEKLKKKQESFCRLQTEKETLFNDSRNKIEELQQR GRAP1_MOUSE GRAP1_MOUSE WEQLQGLESSKQAETSRLQEELAKLSEKLKKKQESFCRLQTEKETLFNDSRNKIEELQQR A2AEW5_MOUSE A2AEW5_MOUSE WEQLQGLESSKQAETSRLQEELAKLSEKLKKKQESFCRLQTEKETLFNDSRNKIEELQQR A2AEW9_MOUSE A2AEW9_MOUSE WEQLQGLESSKQAETSRLQEELAKLSEKLKKKQESFCRLQTEKETLFNDSRNKIEELQQR MATCH *:* * :*****::** :** ***.*:****.**:*::*: CONSENSUS ?EQLQ?LE???Q?????LQEE??KL?EKLKKKQESF?RLQ?EKE?L?NDSR?KIEE?QQR

A7MC52_XENTR A7MC52_XENTR KK---------------------------------------------------------- B2GU72_XENTR B2GU72_XENTR KEEEIKSLTLRNHKLQQDMQAAQQSCAELREQVQSQRQEHERALHGVQE----------- Q4T6K8_TETNG Q4T6K8_TETNG KEEELASLRSLIQKLQADMVAANQTSAQLKEDLQNQEKEQEVALQNLREQASKQSAVSQE B0UYE9_DANRE B0UYE9_DANRE KEEELKSINLRVQKLQTDLMAANQNVGELKEQLQSKQKEHEMAIHALKDQVACQSAVSQE A8K7Z3_HUMAN A8K7Z3_HUMAN KEADHEAQLARTQKLQQELEAANQSLAELRDQRQGERLEHAAALRALQDQVSIQSADAQE B1B0M1_HUMAN B1B0M1_HUMAN KEADHKAQLARTQKLQQELEAANQSLAELRDQRQGERLEHAAALRALQDQVSIQSADAQE GRAP1_HUMAN GRAP1_HUMAN KEADHKAQLARTQKLQQELEAANQSLAELRDQRQGERLEHAAALRALQDQVSIQSADAQE GRAP1_RAT GRAP1_RAT KEADLKAQLARTQKLQQELEAANQSLAELRDQRQGERLEHAAALRALQDQVSSQSADAQE Q3T9D9_MOUSE Q3T9D9_MOUSE KEADLKAQLARTQKLQQELEAANQSLAELRDQRQGERLEHAAALRALQD----------- Q3TZ55_MOUSE Q3TZ55_MOUSE KEADLKAQLARTQKLQQELEAANQSLAELRDQRQGERLEHAAALRALQD----------- A2AEW6_MOUSE A2AEW6_MOUSE KEADLKAQLARTQKLQQELEAANQSLAELRDQRQGERLEHAAALRALQD----------- A2AEW8_MOUSE A2AEW8_MOUSE KEADLKAQLARTQKLQQELEAANQSLAELRDQRQGERLEHAAALRALQDQVSSQSADAQE GRAP1_MOUSE GRAP1_MOUSE KEADLKAQLARTQKLQQELEAANQSLAELRDQRQGERLEHAAALRALQD----------- A2AEW5_MOUSE A2AEW5_MOUSE KEADLKAQLARTQKLQQELEAANQSLAELRDQRQGERLEHAAALRALQD----------- A2AEW9_MOUSE A2AEW9_MOUSE KEADLKAQLARTQKLQQELEAANQSLAELRDQRQGERLEHAAALRALQDQVSSQSADAQE MATCH *: CONSENSUS KE???K????R?QKLQQ?L?AANQS?AELR?Q?Q??R?EH??AL?ALQD???????????

A7MC52_XENTR A7MC52_XENTR ------------------------------------------------------------ B2GU72_XENTR B2GU72_XENTR --------------------QIQSSRTQELTLLREQNSALTLELQQQHHEKEAMLAQKED Q4T6K8_TETNG Q4T6K8_TETNG RVDIILQENDALRTNLAALEQIQTAKTQEMNLLREQQEALAAELSQRRAECEALSAQRDD B0UYE9_DANRE B0UYE9_DANRE QVEGMLSENDALRTNLAALEQIQTVKTQELNLLREQNLALNAELQQRRTDQESFLAQRDD A8K7Z3_HUMAN A8K7Z3_HUMAN QVEGLLAENNALRTSLAALEQIQTAKTQELNMLREQTTGLAAELQQQQAEYEDLMGQKDD B1B0M1_HUMAN B1B0M1_HUMAN QVEGLLAENNALRTSLAALEQIQTAKTQELNMLREQTTGLAAELQQQQAEYEDLMGQKDD GRAP1_HUMAN GRAP1_HUMAN QVEGLLAENNALRTSLAALEQIQTAKTQELNMLREQTTGLAAELQQQQAEYEDLMGQKDD GRAP1_RAT GRAP1_RAT QVEGLLAENNALRTSLAALEQIQTAKTQELNMLREQNTELAAELKHRQADYEELMGQKDD Q3T9D9_MOUSE Q3T9D9_MOUSE --------------------QIQTAKTQELNMLREQTSELASELQHRQAEYEELMGQKDD Q3TZ55_MOUSE Q3TZ55_MOUSE --------------------QIQTAKTQELNMLREQTSELASELQHRQAEYEELMGQKDD A2AEW6_MOUSE A2AEW6_MOUSE --------------------QIQTAKTQELNMLREQTSELASELQHRQAEYEELMGQKDD A2AEW8_MOUSE A2AEW8_MOUSE QVEGLLAENSALRTSLAALEQIQTAKTQELNMLREQTSELASELQHRQAEYEELMGQKDD GRAP1_MOUSE GRAP1_MOUSE --------------------QIQTAKTQELNMLREQTSELASELQHRQAEYEELMGQKDD A2AEW5_MOUSE A2AEW5_MOUSE --------------------QIQTAKTQELNMLREQTSELASELQHRQAEYEELMGQKDD A2AEW9_MOUSE A2AEW9_MOUSE QVEGLLAENSALRTSLAALEQIQTAKTQELNMLREQTSELASELQHRQAEYEELMGQKDD MATCH CONSENSUS ????????????????????QIQTAKTQELN?LREQ???LA?ELQ???AE?E?L??QKDD

A7MC52_XENTR A7MC52_XENTR ------------------------------------------------------------ B2GU72_XENTR B2GU72_XENTR LKAQ--------------------------LEESLRANRRLLEQLQEKEQESERLRQDLD Q4T6K8_TETNG Q4T6K8_TETNG LGSQLQVKHAPKRPHGPRWSGFRSTYLTSRLQESSFANRKLLEQLTEEGLEKDRLLLELE B0UYE9_DANRE B0UYE9_DANRE LNSQ--------------------------LQESNRANSRLLEQLTELGLEKDKLLQDLE A8K7Z3_HUMAN A8K7Z3_HUMAN LNSQ--------------------------LQESLRANSRLLEQLQEIGQEKEQLTQELQ B1B0M1_HUMAN B1B0M1_HUMAN LNSQ--------------------------LQESLRANSRLLEQLQEIGQEKEQLTQELQ GRAP1_HUMAN GRAP1_HUMAN LNSQ--------------------------LQESLRANSRLLEQLQEIGQEKEQLTQELQ GRAP1_RAT GRAP1_RAT LNSQ--------------------------LQESLRANSRLLEQLQEMGQEKEQLIQDLQ Q3T9D9_MOUSE Q3T9D9_MOUSE VNSQ--------------------------LQESLRANSRLLEQLQEIGQEKEQLTQDLQ Q3TZ55_MOUSE Q3TZ55_MOUSE LNSQ--------------------------LQESLRANSRLLEQLQEIGQEKEQLTQDLQ A2AEW6_MOUSE A2AEW6_MOUSE LNSQ--------------------------LQESLRANSRLLEQLQEIGQEKEQLTQDLQ A2AEW8_MOUSE A2AEW8_MOUSE LNSQ--------------------------LQESLRANSRLLEQLQEIGQEKEQLTQDLQ GRAP1_MOUSE GRAP1_MOUSE LNSQ--------------------------LQESLRANSRLLEQLQEIGQEKEQLTQDLQ A2AEW5_MOUSE A2AEW5_MOUSE LNSQ--------------------------LQESLRANSRLLEQLQEIGQEKEQLTQDLQ A2AEW9_MOUSE A2AEW9_MOUSE LNSQ--------------------------LQESLRANSRLLEQLQEIGQEKEQLTQDLQ MATCH CONSENSUS LNSQ??????????????????????????LQESLRANSRLLEQLQE?GQEKE?L?Q?L?

A7MC52_XENTR A7MC52_XENTR --KK-------------------------------------------------------- B2GU72_XENTR B2GU72_XENTR EARK---------------------------SADKRKAMLDELAMEMLQEKSRHKEALGN Q4T6K8_TETNG Q4T6K8_TETNG EAKKVHTHTHTHTQRNRHTLSLLCVVFVRLQTAEKRKAMLDEMAIQLNQEKSNHKEALSD B0UYE9_DANRE B0UYE9_DANRE EARK---------------------------TADKRKVMLDELAIETAQEKSRHKEELSN A8K7Z3_HUMAN A8K7Z3_HUMAN EARK---------------------------SAEKRKAMLDELAMETLQEKSQHKEELGA B1B0M1_HUMAN B1B0M1_HUMAN EARK---------------------------SAEKRKAMLDELAMETLQEKSQHKEELGA GRAP1_HUMAN GRAP1_HUMAN EARK---------------------------SAEKRKAMLDELAMETLQEKSQHKEELGA GRAP1_RAT GRAP1_RAT EARK---------------------------SAEKRKVMLDELAMETLQEKSQHKEELGA Q3T9D9_MOUSE Q3T9D9_MOUSE EARK---------------------------SAEKRKVMLDELAMETLQEKSQHKEELGA Q3TZ55_MOUSE Q3TZ55_MOUSE EARK---------------------------SAEKRKVMLDELAMETLQEKSQHKEELGA A2AEW6_MOUSE A2AEW6_MOUSE EARK---------------------------SAEKRKVMLDELAMETLQEKSQHKEELGA A2AEW8_MOUSE A2AEW8_MOUSE EARK---------------------------SAEKRKVMLDELAMETLQEKSQHKEELGA GRAP1_MOUSE GRAP1_MOUSE EARK---------------------------SAEKRKVMLDELAMETLQEKSQHKEELGA A2AEW5_MOUSE A2AEW5_MOUSE EARK---------------------------SAEKRKVMLDELAMETLQEKSQHKEELGA A2AEW9_MOUSE A2AEW9_MOUSE EARK---------------------------SAEKRKVMLDELAMETLQEKSQHKEELGA MATCH :* CONSENSUS EARK???????????????????????????SAEKRK?MLDELAMETLQEKS?HKEELG?

A7MC52_XENTR A7MC52_XENTR ------------------------------------------------------------ B2GU72_XENTR B2GU72_XENTR LKLQHEKETLSIRAKYEKELRELHEEKNRGEEDLRAQLRDEKARSRELEGHQQTSEELRL Q4T6K8_TETNG Q4T6K8_TETNG LKLQHEKEILGVRARYEKELRGLHEDKNRSEEEIRQQLREEKARTKELEALQPRVEELQA B0UYE9_DANRE B0UYE9_DANRE VRLQHEKEVLSIRARYEKELRGLHEEKNRIEEEIRSQLRDERARTKELEGLQPYVEELKA A8K7Z3_HUMAN A8K7Z3_HUMAN VRLRHEKEVLGVRARYERELRELHEDKKRQEEELRGQIREEKARTRELETLQQTVEELQA B1B0M1_HUMAN B1B0M1_HUMAN VRLRHEKEVLGVRARYERELRELHEDKKRQEEELRGQIREEKARTRELETLQQTVEELQA GRAP1_HUMAN GRAP1_HUMAN VRLRHEKEVLGVRARYERELRELHEDKKRQEEELRGQIREEKARTRELETLQQTVEELQA GRAP1_RAT GRAP1_RAT VRLRHEKEMLGVRARYERELRELHEDKKRQEEELRGQIREEKARTRELENLQHTVEELQA Q3T9D9_MOUSE Q3T9D9_MOUSE VRLRHEKELLGVRARYERELRELREDKKRQEEELRGQIREEKARTRELENLQHTVEELQA Q3TZ55_MOUSE Q3TZ55_MOUSE VRLRHEKELLGVRARYERELRVLHEDKKRQEEELRGQIREEKARTRELENLQHTVEELQA A2AEW6_MOUSE A2AEW6_MOUSE VRLRHEKELLGVRARYERELRELHEDKKRQEEELRGQIREEKARTRELENLQHTVEELQA A2AEW8_MOUSE A2AEW8_MOUSE VRLRHEKELLGVRARYERELRELHEDKKRQEEELRGQIREEKARTRELENLQHTVEELQA GRAP1_MOUSE GRAP1_MOUSE VRLRHEKELLGVRARYERELRELHEDKKRQEEELRGQIREEKARTRELENLQHTVEELQA A2AEW5_MOUSE A2AEW5_MOUSE VRLRHEKELLGVRARYERELRELHEDKKRQEEELRGQIREEKARTRELENLQHTVEELQA A2AEW9_MOUSE A2AEW9_MOUSE VRLRHEKELLGVRARYERELRELHEDKKRQEEELRGQIREEKARTRELENLQHTVEELQA MATCH CONSENSUS VRL?HEKE?LGVRARYE?ELR?LHEDK?R?EEELR?Q?REEKARTRELE?LQ?TVEELQA

A7MC52_XENTR A7MC52_XENTR ------------------------------------------------------------ B2GU72_XENTR B2GU72_XENTR QIHSLEGTKGWFERRLKEAE--------ETVEKNQMRHEEDLAKVAREHSANLQVHTD-- Q4T6K8_TETNG Q4T6K8_TETNG HILSMEGTKGWFERRLKEAEVISTAAVREKIEQKSLEHQDNIEKLQNEHQLQVAEKQSEM B0UYE9_DANRE B0UYE9_DANRE QVQSMEGTKGWFERRLKEAE--------ETMERSKLDHAEEIKRLQKDHTLQLEAKAAEV A8K7Z3_HUMAN A8K7Z3_HUMAN QVHSMDGAKGWFERRLKEAE--------ESLQQQQQEQEEALKQCREQHAAELKGKEEEL B1B0M1_HUMAN B1B0M1_HUMAN QVHSMDGAKGWFERRLKEAE--------ESLQQQQQEQEEALKQCREQHAAELKGKEEEL GRAP1_HUMAN GRAP1_HUMAN QVHSMDGAKGWFERRLKEAE--------ESLQQQQQEQEEALKQCREQHAAELKGKEEEL GRAP1_RAT GRAP1_RAT QVHSMDGAKGWFERRLKEAE--------ESLLQQEQEQEETLKQCREQHAAELKGKEEEL Q3T9D9_MOUSE Q3T9D9_MOUSE QVHSMDGAKGWFERRLKEAE--------ESLLQQQQEQEETLKLCREEHAAELKGKDEEL Q3TZ55_MOUSE Q3TZ55_MOUSE QVHSMDGAKGWFERRLKEAE--------ESLLQQQQEQEETLKLCREEHAAELKGKDEEL A2AEW6_MOUSE A2AEW6_MOUSE QVHSMDGAKGWFERRLKEAE--------ESLQQQQQEQEETLKLCREEHAAELKGKDEEL A2AEW8_MOUSE A2AEW8_MOUSE QVHSMDGAKGWFERRLKEAE--------ESLQQQQQEQEETLKLCREEHAAELKGKDEEL GRAP1_MOUSE GRAP1_MOUSE QVHSMDGAKGWFERRLKEAE--------ESLQQQQQEQEETLKLCREEHAAELKGKDEEL A2AEW5_MOUSE A2AEW5_MOUSE QVHSMDGAKGWFERRLKEAE--------ESLQQQQQEQEETLKLCREEHAAELKGKDEEL A2AEW9_MOUSE A2AEW9_MOUSE QVHSMDGAKGWFERRLKEAE--------ESLQQQQQEQEETLKLCREEHAAELKGKDEEL MATCH CONSENSUS QVHSM?G?KGWFERRLKEAE????????E???Q???E?EE?LK?????H?A?L??K??E?

A7MC52_XENTR A7MC52_XENTR ------------------------------------------------------------ B2GU72_XENTR B2GU72_XENTR ------------------------------------------------------------ Q4T6K8_TETNG Q4T6K8_TETNG ERLTEQLLEVEKQKDEHNNTIGKLRQEIKDTVDGQRILEKKGSSAVRTFHTHTHTHTHTH B0UYE9_DANRE B0UYE9_DANRE DAVQQQVTEMEKEREDLNNTIGKLKQEIKDTVDGQRILEKKGSSALKDLKRQLHLERKRA A8K7Z3_HUMAN A8K7Z3_HUMAN QDVRDQLEQAQEERDCHLKTISSLKQEVKDTVDGQRILEKKGSAALKDLKRQLHLERKRA B1B0M1_HUMAN B1B0M1_HUMAN QDVRDQLEQAQEERDCHLKTISSLKQEVKDTVDGQRILEKKGSAALKDLKRQLHLERKRA GRAP1_HUMAN GRAP1_HUMAN QDVRDQLEQAQEERDCHLKTISSLKQEVKDTVDGQRILEKKGSAALKDLKRQLHLERKRA GRAP1_RAT GRAP1_RAT QNVRDQLQQAQEERDGHVKTISNLKQEVKDTVDGQRILEKKGSAVLKDLKRQLHLERKRA Q3T9D9_MOUSE Q3T9D9_MOUSE ------------------------------------------------------------ Q3TZ55_MOUSE Q3TZ55_MOUSE ------------------------------------------------------------ A2AEW6_MOUSE A2AEW6_MOUSE ------------------------------------------------------------ A2AEW8_MOUSE A2AEW8_MOUSE QNVREQLQQAQEERDGHVKTISNLKQEVKDTVDGQRILEKKGSAVLKDLKRQLHLERKRA GRAP1_MOUSE GRAP1_MOUSE QNVREQLQQAQEERDGHVKTISNLKQEVKDTVDGQRILEKKGSAVLKDLKRQLHLERKRA A2AEW5_MOUSE A2AEW5_MOUSE ------------------------------------------------------------ A2AEW9_MOUSE A2AEW9_MOUSE QNVREQLQQAQEERDGHVKTISNLKQEVKDTVDGQRILEKKGSAVLKDLKRQLHLERKRA MATCH CONSENSUS ????????????????????????????????????????????????????????????

A7MC52_XENTR A7MC52_XENTR ------------------------------------------------------------ B2GU72_XENTR B2GU72_XENTR ------------------------------------------------------------ Q4T6K8_TETNG Q4T6K8_TETNG THTH-----TLQSEKETECLEELVLSEISSPSRSQPTGDSSSISSFSYKDMMKETQTT-N B0UYE9_DANRE B0UYE9_DANRE DKLQERLQEILTNTKTRTGLEELVLSEISSPSRTQQTGDSSSISSFSYRDIMKDGASAPS A8K7Z3_HUMAN A8K7Z3_HUMAN DKLQERLQDILTNSKSRSGLEELVLSEMNSPSRT-QTGDSSSISSFSYREILREKESSAV B1B0M1_HUMAN B1B0M1_HUMAN DKLQERLQDILTNSKSRSGLEELVLSEMNSPSRT-QTGDSSSISSFSYREILREKESSAV GRAP1_HUMAN GRAP1_HUMAN DKLQERLQDILTNSKSRSGLEELVLSEMNSPSRT-QTGDSSSISSFSYREILREKESSAV GRAP1_RAT GRAP1_RAT DKLQERLQEILTNSKSRTGLEELVLSEMNSPSRT-QTGDSSSVSSFSYREILKEKESSAI Q3T9D9_MOUSE Q3T9D9_MOUSE ------------------------------------------------------------ Q3TZ55_MOUSE Q3TZ55_MOUSE ------------------------------------------------------------ A2AEW6_MOUSE A2AEW6_MOUSE ------------------------------------------------------------ A2AEW8_MOUSE A2AEW8_MOUSE DKLQERLQEILTNSKSRTGLEELVLSEMNSPSRT-QTGDSSSVSSFSYREILKEKESSAI GRAP1_MOUSE GRAP1_MOUSE DKLQERLQEILTNSKSRTGLEELVLSEMNSPSRT-QTGDSSSVSSFSYREILKEKESSAI A2AEW5_MOUSE A2AEW5_MOUSE ------------------------------------------------------------ A2AEW9_MOUSE A2AEW9_MOUSE DKLQERLQEILTNSKSRTGLEELVLSEMNSPSRT-QTGDSSSVSSFSYREILKEKESSAI MATCH CONSENSUS ????????????????????????????????????????????????????????????

A7MC52_XENTR A7MC52_XENTR ------------------------------------------------------------ B2GU72_XENTR B2GU72_XENTR ------------------------------------------------------------ Q4T6K8_TETNG Q4T6K8_TETNG QSKSGGGSPQSQ--RPADLSDDEVGELFQRLAE-----------VKHLEVSCSSMAEDIC B0UYE9_DANRE B0UYE9_DANRE TNKSNTSSPQSQ--RPADLSDDEVSELFQRLAEVQQEKWMLEEKVKHLEVSCASMADDIC A8K7Z3_HUMAN A8K7Z3_HUMAN PARSLSSSPQAQPPRPAELSDEEVAELFQRLAETQQEKWMLEEKVKHLEVSSASMAEDLC B1B0M1_HUMAN B1B0M1_HUMAN PARSLSSSPQAQPPRPAELSDEEVAELFQRLAETQQEKWMLEEKVKHLEVSSASMAEDLC GRAP1_HUMAN GRAP1_HUMAN PARSLSSSPQAQPPRPAELSDEEVAELFQRLAETQQEKWMLEEKVKHLEVSSASMAEDLC GRAP1_RAT GRAP1_RAT PARSLSSSPQAQPPRPAELSDEEVAELFQRLAETQQEKWMLEEKVKHLEVSSASMAEDLC Q3T9D9_MOUSE Q3T9D9_MOUSE ------------------------------------------------------------ Q3TZ55_MOUSE Q3TZ55_MOUSE ------------------------------------------------------------ A2AEW6_MOUSE A2AEW6_MOUSE ------------------------------------------------------------ A2AEW8_MOUSE A2AEW8_MOUSE PARSLSSSPQAQPPRPAELSDEEVAELFQRLAETQQEKWMLEEKVKHLEVSSASMAEDLC GRAP1_MOUSE GRAP1_MOUSE PARSLSSSPQAQPPRPAELSDEEVAELFQRLAETQQEKWMLEEKVKHLEVSSASMAEDLC A2AEW5_MOUSE A2AEW5_MOUSE ------------------------------------------------------------ A2AEW9_MOUSE A2AEW9_MOUSE PARSLSSSPQAQPPRPAELSDEEVAELFQRLAETQQEKWMLEEKVKHLEVSSASMAEDLC MATCH CONSENSUS ????????????????????????????????????????????????????????????

A7MC52_XENTR A7MC52_XENTR ------------------------------------------------------------ B2GU72_XENTR B2GU72_XENTR ----------------------------PCGGNGVGGR---------------------- Q4T6K8_TETNG Q4T6K8_TETNG RKSAIIETYVMDSRIDVSGCAAGGHGASQGDRGGLGSVLRDLVKPGDENLREMNKKLQNM B0UYE9_DANRE B0UYE9_DANRE KKSAIIETYVMDSRRDVSG-GVGLAHSAQPDRGGLSSVLRDLVKPGDENLREMNKKLQNM A8K7Z3_HUMAN A8K7Z3_HUMAN RKSAIIETYVMDSRIDVSV-AAG-----HTDRSGLGSVLRDLVKPGDENLREMNKKLQNM B1B0M1_HUMAN B1B0M1_HUMAN RKSAIIETYVMDSRIDVSV-AAG-----HTDRSGLGSVLRDLVKPGDENLREMNKKLQNM GRAP1_HUMAN GRAP1_HUMAN RKSAIIETYVMDSRIDVSV-AAG-----HTDRSGLGSVLRDLVKPGDENLREMNKKLQNM GRAP1_RAT GRAP1_RAT RKSAIIETYVMDSRIDVSV-AAG-----HTDRSGLGSVLRDLVKPGDENLREMNKKLQNM Q3T9D9_MOUSE Q3T9D9_MOUSE ------------------------------------------------------------ Q3TZ55_MOUSE Q3TZ55_MOUSE ------------------------------------------------------------ A2AEW6_MOUSE A2AEW6_MOUSE ------------------------------------------------------------ A2AEW8_MOUSE A2AEW8_MOUSE RKSAIIETYVMDSRIDVSV-AAG-----HTDRSGLGSVLRDLVKPGDENLREMNKKLQNM GRAP1_MOUSE GRAP1_MOUSE RKSAIIETYVMDSRIDVSV-AAG-----HTDRSGLGSVLRDLVKPGDENLREMNKKLQNM A2AEW5_MOUSE A2AEW5_MOUSE ------------------------------------------------------------ A2AEW9_MOUSE A2AEW9_MOUSE RKSAIIETYVMDSRIDVSV-AAG-----HTDRSGLGSVLRDLVKPGDENLREMNKKLQNM MATCH CONSENSUS ????????????????????????????????????????????????????????????

A7MC52_XENTR A7MC52_XENTR ------------------------------------------------------------ B2GU72_XENTR B2GU72_XENTR ------------------------------------------------------------ Q4T6K8_TETNG Q4T6K8_TETNG LEEQLTKNMHLQK----VASQRPRRSGPAQPPPVFLCRTWSSCPRNWFGSVKTAAPGAAR B0UYE9_DANRE B0UYE9_DANRE LEEQLTKNMHLQKDLEVLSQEIVRLSKDT------------------------------- A8K7Z3_HUMAN A8K7Z3_HUMAN LEEQLTKNMHLHKDMEVLSQEIVRLSKECVGPP--------------------------- B1B0M1_HUMAN B1B0M1_HUMAN LEEQLTKNMHLHKDMEVLSQEIVRLSKECVGPP--------------------------- GRAP1_HUMAN GRAP1_HUMAN LEEQLTKNMHLHKDMEVLSQEIVRLSKECVGPP--------------------------- GRAP1_RAT GRAP1_RAT LEEQLTKNMHLHKDMEVLSQEIVRLSKECVGSP--------------------------- Q3T9D9_MOUSE Q3T9D9_MOUSE ------------------------------------------------------------ Q3TZ55_MOUSE Q3TZ55_MOUSE ------------------------------------------------------------ A2AEW6_MOUSE A2AEW6_MOUSE ------------------------------------------------------------ A2AEW8_MOUSE A2AEW8_MOUSE LEEQLTKNMHLHKDMEVLSQEIVRLSKECVGSP--------------------------- GRAP1_MOUSE GRAP1_MOUSE LEEQLTKNMHLHKDMEVLSQEIVRLSKECVGSP--------------------------- A2AEW5_MOUSE A2AEW5_MOUSE ------------------------------------------------------------ A2AEW9_MOUSE A2AEW9_MOUSE LEEQLTKNMHLHKDMEVLSQEIVRLSKECVGSP--------------------------- MATCH CONSENSUS ????????????????????????????????????????????????????????????

A7MC52_XENTR A7MC52_XENTR ------------------------------------------------------------ B2GU72_XENTR B2GU72_XENTR ------------------------------------------------------------ Q4T6K8_TETNG Q4T6K8_TETNG PGPNESAHPPTRPPFPSGRCWSHGPLQPRSARPPLVPAGIRDDPGDLQGGPARLFRVRLN B0UYE9_DANRE B0UYE9_DANRE -------------------------------------------TPAENSKTTG------- A8K7Z3_HUMAN A8K7Z3_HUMAN -------------------------------------------DPDLEPGETS------- B1B0M1_HUMAN B1B0M1_HUMAN -------------------------------------------DPDLEPGETS------- GRAP1_HUMAN GRAP1_HUMAN -------------------------------------------DPDLEPGETS------- GRAP1_RAT GRAP1_RAT -------------------------------------------DPDLEPGEAN------- Q3T9D9_MOUSE Q3T9D9_MOUSE ------------------------------------------------------------ Q3TZ55_MOUSE Q3TZ55_MOUSE ------------------------------------------------------------ A2AEW6_MOUSE A2AEW6_MOUSE ------------------------------------------------------------ A2AEW8_MOUSE A2AEW8_MOUSE -------------------------------------------DPDLEPGEAN------- GRAP1_MOUSE GRAP1_MOUSE -------------------------------------------DPDLEPGEAN------- A2AEW5_MOUSE A2AEW5_MOUSE ------------------------------------------------------------ A2AEW9_MOUSE A2AEW9_MOUSE -------------------------------------------DPDLEPGEAN------- MATCH CONSENSUS ????????????????????????????????????????????????????????????

A7MC52_XENTR A7MC52_XENTR --------- B2GU72_XENTR B2GU72_XENTR --------- Q4T6K8_TETNG Q4T6K8_TETNG VQERERRAA B0UYE9_DANRE B0UYE9_DANRE --------- A8K7Z3_HUMAN A8K7Z3_HUMAN --------- B1B0M1_HUMAN B1B0M1_HUMAN --------- GRAP1_HUMAN GRAP1_HUMAN --------- GRAP1_RAT GRAP1_RAT --------- Q3T9D9_MOUSE Q3T9D9_MOUSE --------- Q3TZ55_MOUSE Q3TZ55_MOUSE --------- A2AEW6_MOUSE A2AEW6_MOUSE --------- A2AEW8_MOUSE A2AEW8_MOUSE --------- GRAP1_MOUSE GRAP1_MOUSE --------- A2AEW5_MOUSE A2AEW5_MOUSE --------- A2AEW9_MOUSE A2AEW9_MOUSE --------- MATCH CONSENSUS ?????????


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