Alignment of the gene Family HBG080556 of HOVERGEN

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Threshold: 50% 80% 100%
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Isoforms are ON
A2CF03_DANRE A2CF03_DANRE ------------------------------------------------------------ B5DFD9_RAT B5DFD9_RAT ------------------------------------------------------------ A2BE28_MOUSE A2BE28_MOUSE ------------------------------------------------------------ A2BE30_MOUSE A2BE30_MOUSE ------------------------------------------------------------ B3KNR6_HUMAN B3KNR6_HUMAN ------------------------------------------------------------ LAS1L_HUMAN LAS1L_HUMAN ------------------------------------------------MSWESGAGPGLG A6QP94_BOVIN A6QP94_BOVIN EADREMEADHEMEDDLQCGGTRPELDVEPVEPDVEPVEPDVEPDVEPDVRSESEIEPGLG Q08D82_BOVIN Q08D82_BOVIN ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

A2CF03_DANRE A2CF03_DANRE ------------------MKKETVGKTRHVVPWMNKAEYEHVLEYLYSKEPALQKHALHR B5DFD9_RAT B5DFD9_RAT ------------------------------------------------------------ A2BE28_MOUSE A2BE28_MOUSE ---MDRVWRAWDGQSFKENQPESPSARGIVVSWLSRAEWEQVTVYLFCDDHKLQQYALNR A2BE30_MOUSE A2BE30_MOUSE ---MDRVWRAWDGQSFKENQPESPSARGIVVSWLSRAEWEQVTVYLFCDDHKLQQYALNR B3KNR6_HUMAN B3KNR6_HUMAN ------------------------------------------------------------ LAS1L_HUMAN LAS1L_HUMAN SQGMDLVWSAWYGKCVKGKGSLPLSAHGIVVAWLSRAEWDQVTVYLFCDDHKLQRYALNR A6QP94_BOVIN A6QP94_BOVIN PRGMDLVWSAWCGKCVKEKGSSPLWAQRIVVAWLSRAEWDQVMVYLFSDDYKLQRYALNR Q08D82_BOVIN Q08D82_BOVIN ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

A2CF03_DANRE A2CF03_DANRE ISAWKGRFGQSTPVAVESTADLVRCQVLDSTGQLEANDLVLLYGMALVRFVNLITERQQK B5DFD9_RAT B5DFD9_RAT ------------------------------------------------------------ A2BE28_MOUSE A2BE28_MOUSE ITVWRSRLGNELPLAVASTADLVRCKLIDAAGTLGTDELRLLYGMALVRFVNLISERKTK A2BE30_MOUSE A2BE30_MOUSE ITVWRSRLGNELPLAVASTADLVRCKLIDAAGTLGTDELRLLYGMALVRFVNLISERKTK B3KNR6_HUMAN B3KNR6_HUMAN ------------------------------------------------------------ LAS1L_HUMAN LAS1L_HUMAN ITVWRSRSGNELPLAVASTADLIRCKLLDVTGGLGTDELRLLYGMALVRFVNLISERKTK A6QP94_BOVIN A6QP94_BOVIN ITVWRSRLGNELPLAVASTADLVRCKLMDVTGGLGTDELRLLYGMALVRFVNLISERKTK Q08D82_BOVIN Q08D82_BOVIN ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

A2CF03_DANRE A2CF03_DANRE KVAKPLRRLARKINIPEWVVNLRHDLTHRRLPSLKWCRKGCGFVLDWLHQEYWSRQMGNQ B5DFD9_RAT B5DFD9_RAT -----------------------MGIPHKPE----------------------------- A2BE28_MOUSE A2BE28_MOUSE CSNLPLKYLAQEVNIPDWIVELRHNLTHKKMPHINECRRGCYFVLNWLQKTYWSRQLEGS A2BE30_MOUSE A2BE30_MOUSE CSNLPLKYLAQEVNIPDWIVELRHNLTHKKMPHINECRRGCYFVLNWLQKTYWSRQLEGS B3KNR6_HUMAN B3KNR6_HUMAN ------------------------------------------------------------ LAS1L_HUMAN LAS1L_HUMAN FAKVPLKCLAQEVNIPDWIVDLRHELTHKKMPHINDCRRGCYFVLDWLQKTYWCRQLENS A6QP94_BOVIN A6QP94_BOVIN FAKLPLKFLAQEVNIPDWIVELRHELTHKKMPHINDCRRGCYFVLDWLQNTYWCRQMENS Q08D82_BOVIN Q08D82_BOVIN -----------------------MDVSHKPE----------------------------- MATCH CONSENSUS ???????????????????????????H????????????????????????????????

A2CF03_DANRE A2CF03_DANRE LTEDWNSSSDDEGEDDVVKRHEGDLLSRQ------------------------------- B5DFD9_RAT B5DFD9_RAT ------------------------------------------------------------ A2BE28_MOUSE A2BE28_MOUSE LKETWELDEDQLDAEDP-EEEEREIIADDVLEEIPEPQDDDKDEELAVEDDANTKGN--- A2BE30_MOUSE A2BE30_MOUSE LKETWELDEDQLDAEDP-EEEEREIIADDVLEEIPEPQDDDKDEELAVEDDANTKGN--- B3KNR6_HUMAN B3KNR6_HUMAN ------------------------------------------------------------ LAS1L_HUMAN LAS1L_HUMAN LRETWELEEFREGIEEEDQEEDKNIVVDDITEQKPEPQDDGKSTESDVKADGDSKGS--- A6QP94_BOVIN A6QP94_BOVIN LRETWELEEEREETDEADQEEDKKIVVDDITEQNPEPKDEEKGVELNVKTDGDRESNKDG Q08D82_BOVIN Q08D82_BOVIN ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

A2CF03_DANRE A2CF03_DANRE -----------REIEAHKKIRELLISYEREQFQTYEELAKHGGQGGAWPDASADLSWILT B5DFD9_RAT B5DFD9_RAT ------------------------------------------------------------ A2BE28_MOUSE A2BE28_MOUSE EEVASHPEPSSRHKELYEKARELLVSYEEEQFKVLEKHRHLLQAIKVWNNLSPRVQCILE A2BE30_MOUSE A2BE30_MOUSE EEVASHPEPSSRHKELYEKARELLVSYEEEQFKVLEKHRHLLQAIKVWNNLSPRVQCILE B3KNR6_HUMAN B3KNR6_HUMAN ------------------------------------------------------------ LAS1L_HUMAN LAS1L_HUMAN EEVDSHCKKALSHKELYERARELLVSYEEEQFTVLEKFRYLPKAIKAWNNPSPRVECVLA A6QP94_BOVIN A6QP94_BOVIN KEVDPLLQKALRHKQLYERARELLVSYEEEQFKVLEKYRHLPQAIKAWNNLSPPVECILA Q08D82_BOVIN Q08D82_BOVIN ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

A2CF03_DANRE A2CF03_DANRE QIKHFATESRDVLVDVLLQDGFLIPTTEQLESLDVDPSED----------------SVDV B5DFD9_RAT B5DFD9_RAT --------------------------------------------------------NIDL A2BE28_MOUSE A2BE28_MOUSE ELKSISWENRDAVLDAFLDDGFLIPTFEQLAALQIEYEDGQTEVQKGEVTEPNSHKNIDL A2BE30_MOUSE A2BE30_MOUSE ELKSISWENRDAVLDAFLDDGFLIPTFEQLAALQIEYEE-----------------NIDL B3KNR6_HUMAN B3KNR6_HUMAN ------------------------------------------------------------ LAS1L_HUMAN LAS1L_HUMAN ELKGVTCENREAVLDAFLDDGFLVPTFEQLAALQIEYEDGQTEVQRGEGTDPKSHKNVDL A6QP94_BOVIN A6QP94_BOVIN ELKGITLENREAVLDAFLDDGFLIPTFEQLAALQIEYEE-----------------NVDL Q08D82_BOVIN Q08D82_BOVIN --------------------------------------------------------NVDL MATCH CONSENSUS ??????????????????????????????????????????????????????????D?

A2CF03_DANRE A2CF03_DANRE FSPSLPRVFFHFWLPLLRVLNSSGFINMILDKLFSELSNEPSTP-RMYYIASWISEIILC B5DFD9_RAT B5DFD9_RAT NEVLVPKPFSQFWQPLLRGLHSQTFTQALLERMFSELSTLGRTGIRPTYILRWTVELIVA A2BE28_MOUSE A2BE28_MOUSE NEVLVPKPFSQFWQPLLRGLHSQTFTQALLERMFSELSTVGSTGIRPTYILRWTVELIVA A2BE30_MOUSE A2BE30_MOUSE NEVLVPKPFSQFWQPLLRGLHSQTFTQALLERMFSELSTVGSTGIRPTYILRWTVELIVA B3KNR6_HUMAN B3KNR6_HUMAN ------------------------------------------------------------ LAS1L_HUMAN LAS1L_HUMAN NDVLVPKPFSQFWQPLLRGLHSQNFTQALLERMLSELPALGISGIRPTYILRWTVELIVA A6QP94_BOVIN A6QP94_BOVIN DDVLVPKPFSQFWQPLLRGLHSQTFTQALLERMLSELPALGNTGIRPTYILRWTTELIVA Q08D82_BOVIN Q08D82_BOVIN DDVLVPKPFSQFWQPLLRGLHSQTFTQALLERMLSELPALGNTGIRPTYILRWTTELIVA MATCH CONSENSUS ?????P??F??FW?PLLR?L?S??F????L????SEL????????R??YI??W??E?I??

A2CF03_DANRE A2CF03_DANRE NSKTETKAHRKQKVSKE-----RIFVNRLHFRWHSLISACVNAPCPATPFLLRQILNDMD B5DFD9_RAT B5DFD9_RAT NTKTGRNARRFSAGQWEARRSWRLFNCSSTLDWPQVIEACLGSPCWASLQLLQVVFKAMG A2BE28_MOUSE A2BE28_MOUSE NTKTGRNARRFSASQWEARKSWRLFNCSATLDWPQVIESCLGSPCWASPQLLQVVFKAMG A2BE30_MOUSE A2BE30_MOUSE NTKTGRNARRFSASQWEARKSWRLFNCSATLDWPQVIESCLGSPCWASPQLLQVVFKAMG B3KNR6_HUMAN B3KNR6_HUMAN ----------------------------------------------------------MG LAS1L_HUMAN LAS1L_HUMAN NTKTGRNARRFSAGQWEARRGWRLFNCSASLDWPRMVESCLGSPCWASPQLLRIIFKAMG A6QP94_BOVIN A6QP94_BOVIN NTKTGRNARRFSASQWEARKNWRLFNCSASLDWPQVVESCLGSPCWASPQLLQLIFKAMG Q08D82_BOVIN Q08D82_BOVIN NTKTGRNARRFSASQWEARKNWRLFNCSASLDWPQVVESCLGSPCWASPQLLQLIFKAMG MATCH *. CONSENSUS N?KT???A?R??????E?????R?F???????W??????C???PC?A???LL??????MG

A2CF03_DANRE A2CF03_DANRE KPLPPDAQKNLLQLCSIYT-----------QGYHCDPSAGPSDPAEPVYTLQNLQERLK- B5DFD9_RAT B5DFD9_RAT EVLPDEEQEKLLRVCSIYTQNGESGLAKAVEGSSSSSSSSSSTGKAP-YTLDTLHQDLQP A2BE28_MOUSE A2BE28_MOUSE QVLPDEEQEKLLRVCSIYTQNGENGLAKAIEG-----SSSSSTGKAP-YTLDTLHEDLQP A2BE30_MOUSE A2BE30_MOUSE QVLPDEEQEKLLRVCSIYTQNGENGLAKAIEG-----SSSSSTGKAP-YTLDTLHEDLQP B3KNR6_HUMAN B3KNR6_HUMAN QGLPDEEQEKLLRICSIYTQSGENSLVQ--EG-----SEASPIGKSP-YTLDSLYWSVKP LAS1L_HUMAN LAS1L_HUMAN QGLPDEEQEKLLRICSIYTQSGENSLVQ--EG-----SEASPIGKSP-YTLDSLYWSVKP A6QP94_BOVIN A6QP94_BOVIN QFLPDEEQEKLLRICSIYTQSGEN-LVQ--EG-----SEASPIGKSP-YTVDNLYLILKP Q08D82_BOVIN Q08D82_BOVIN QFLPDEEQEKLLRICSIYTQSGEN-LVQ--EG-----SEASPIGKSP-YTVDNLYLILKP MATCH : ** : *::**::***** :* * ... * **::.* :: CONSENSUS ??LPDEEQEKLLR?CSIYTQ?GE??L????EG?????S??S??GK?P?YT?D?L?????P

A2CF03_DANRE A2CF03_DANRE --SNTSQNRDVHSANHTAKTTQIPPTEELQEKLSTET----------------------- B5DFD9_RAT B5DFD9_RAT PATNCESEGNIQ-QKEQDNLTDVKPEEEEKENVEEEEEEEKEEAEMEEEE--KEEEEEQE A2BE28_MOUSE A2BE28_MOUSE PGTNCESEESIQ-QKEQGNLKDVKQEEKKENEEEEKEEEEMEEEEEEEEEEKEEEEEEQE A2BE30_MOUSE A2BE30_MOUSE PGTNCESEESIQ-QKEQGNLKDVKQEEKKENEEEEKEEEEMEEEEEEEEEEKEEEEEEQE B3KNR6_HUMAN B3KNR6_HUMAN ASSSFGSEAKAQQQEEQGSVNDVKEEEKEEKEVLPDQ---------------V---EEEE LAS1L_HUMAN LAS1L_HUMAN ASSSFGSEAKAQQQEEQGSVNDVKEEEKEEKEVLPDQ---------------V---EEEE A6QP94_BOVIN A6QP94_BOVIN AGSSSGAEGEAQKQEEQGNLNDVKEDEKENKEAVEDQ---------------VEENEEEE Q08D82_BOVIN Q08D82_BOVIN AGSSSGAEGEAQKQEEQGNLNDVKEDEKENKEAVEDQ---------------VEENEEEE MATCH :. : . : :. . .:: *: ::: . CONSENSUS ???????E???Q?Q?EQ????DVK??E?????????????????????????????EE?E

A2CF03_DANRE A2CF03_DANRE ------------------------------------------------------------ B5DFD9_RAT B5DFD9_RAT QEEHQEEEQEEEEEEEEEQKVFQDQMEADAEESDGLGEEEEVDEDEDDDEDDDYDDDDDD A2BE28_MOUSE A2BE28_MOUSE QEEHQEEEQ-EEEEEEENQKVFQDQMEADVEESDDVEEEEEVD-DEEEDEDDDY--DDDE A2BE30_MOUSE A2BE30_MOUSE QEEHQEEEQ-EEEEEEENQKVFQDQMEADVEESDDVEEEEEVD-DEEEDEDDDY--DDDE B3KNR6_HUMAN B3KNR6_HUMAN ENDDQEEEE-----------------------------------EDEDD-------EDDE LAS1L_HUMAN LAS1L_HUMAN ENDDQEEEE-----------------------------------EDEDD-------EDDE A6QP94_BOVIN A6QP94_BOVIN ENDHQKWEE-----------------------------------EEEDDGHDDNDNDDED Q08D82_BOVIN Q08D82_BOVIN ENDHQKWEE-----------------------------------EEEDDGHDDNDNDDED MATCH CONSENSUS ????Q??E????????????????????????????????????????D????????D??

A2CF03_DANRE A2CF03_DANRE ------------------------VQERNSALQGSAWTVCTDKVPWKHYPLGKVPGQPED B5DFD9_RAT B5DFD9_RAT DEDGMDMGGFSLLQGSYVLENTRIMSQKREALQGSAWQLSSDDVRWGIFPIGRVPGQTED A2BE28_MOUSE A2BE28_MOUSE EEDRMEVGAFSLAQGSSVFENTRTTSRKREALQGSAWQVSSEDVRWGTFPLGRLPGQTED A2BE30_MOUSE A2BE30_MOUSE EEDRMEVGAFSLAQGSSVFENTRTTSRKREALQGSAWQVSSEDVRWGTFPLGRLPGQTED B3KNR6_HUMAN B3KNR6_HUMAN EEDRMEVGPFSTGQESPTAENARLLAQKRGALQGSAWQVSSEDVRWDTFPLGRMPGQTED LAS1L_HUMAN LAS1L_HUMAN EEDRMEVGPFSTGQESPTAENARLLAQKRGALQGSAWQVSSEDVRWDTFPLGRMPGQTED A6QP94_BOVIN A6QP94_BOVIN EEDRMEVGPFSTEEESPTAENARLLAQKRGALQDSAWQVSSEDVRWDTFPLGRMPGQTED Q08D82_BOVIN Q08D82_BOVIN EEDRMEVGPFSTEEESPTAENARLLAQKRGALQDSAWQVSSEDVRWDTFPLGRMPGQTED MATCH .:. ***.*** :.::.* * :*:*::***.** CONSENSUS ?ED?M??G?FS????S???EN?R????KR?ALQ?SAWQVSS?DVRW??FPLGR?PGQTED

A2CF03_DANRE A2CF03_DANRE PSCLVVESFSTFTVFDQQVELDQLPQQHGNRSVPIQSRGASGS------------DGLLW B5DFD9_RAT B5DFD9_RAT PTELMLDNYDTMYLLDQPVLEHRLEPQKSKSSSTLGLCCGSNN-----NGGVGNMEGLLW A2BE28_MOUSE A2BE28_MOUSE PAELMLDNYDTMYLLDQPVIEHRLEPQKSK-SSTLSLCCGGSNTNSSSSSSSGNMEGLLW A2BE30_MOUSE A2BE30_MOUSE PAELMLDNYDTMYLLDQPVIEHRLEPQKSK-SSTLSLCCGGSNTNSSSSSSSGNMEGLLW B3KNR6_HUMAN B3KNR6_HUMAN PAELMLENYDTMYLLDQPVLEQRLEPSTCK-TDTLGLSCGVGSGNCS-NSSSSNFEGLLW LAS1L_HUMAN LAS1L_HUMAN PAELMLENYDTMYLLDQPVLEQRLEPSTCK-TDTLGLSCGVGSGNCS-NSSSSNFEGLLW A6QP94_BOVIN A6QP94_BOVIN PAELMLENYDTMYLLDQPVLEQRLEPPACK-IGTLGLSCSSGS------NDSGNLDQLLW Q08D82_BOVIN Q08D82_BOVIN PAELMLENYDTMYLLDQPVLEQRLEPPACK-IGTLGLSCSSGS------NDSGNLDQLLW MATCH *: *:::.:.*: ::** * .:* : .: . .. : *** CONSENSUS P?ELML?NYDTMYLLDQPV?E?RLEP???K???TL?L?C??????????????N???LLW

A2CF03_DANRE A2CF03_DANRE THSDMSKLKAGLTLF B5DFD9_RAT B5DFD9_RAT NQGQMHGLKAGLQLF A2BE28_MOUSE A2BE28_MOUSE NQGQMHGLKAGLQLF A2BE30_MOUSE A2BE30_MOUSE NQGQMHGLKAGLQLF B3KNR6_HUMAN B3KNR6_HUMAN SQGQLHGLKTGLQLF LAS1L_HUMAN LAS1L_HUMAN SQGQLHGLKTGLQLF A6QP94_BOVIN A6QP94_BOVIN SQEELHMLKTSVQLF Q08D82_BOVIN Q08D82_BOVIN SQEELHMLKTSVQLF MATCH .: :: **:.: ** CONSENSUS ?Q???H?LK???QLF


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