Alignment of the gene Family HBG083012 of HOVERGEN

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Isoforms are ON
B0S4Y4_DANRE B0S4Y4_DANRE ------------------------------------------------------------ H6ST3_DANRE H6ST3_DANRE ------------------------------------------------------------ Q4S0B1_TETNG Q4S0B1_TETNG ------------------------------------------------------------ Q4TGL7_TETNG Q4TGL7_TETNG ------------------------------------------------------------ Q3UTM4_MOUSE Q3UTM4_MOUSE ------------------------------------------------------------ B3KX95_HUMAN B3KX95_HUMAN ------------------------------------------------------------ H6ST3_HUMAN H6ST3_HUMAN ------------------------------------------------------------ Q148Q1_MOUSE Q148Q1_MOUSE ------------------------------------------------------------ H6ST3_MOUSE H6ST3_MOUSE ------------------------------------------------------------ Q149R8_MOUSE Q149R8_MOUSE ------------------------------------------------------------ H6ST2_CHICK H6ST2_CHICK ------------------------------------------------------------ B7Z5H6_HUMAN B7Z5H6_HUMAN ------------------------------------------------------------ B1AUS3_MOUSE B1AUS3_MOUSE ALPAFAARALGPPLQPEQGAPARTTCPRRHSRVEAELAASRPGSVAASVRAGPPRGVSLG H6ST2_MOUSE H6ST2_MOUSE ALPAFAARALGPPLQPEQGAPARTTCPRRHSRVEAELAASRPGSVAASVRAGPPRGVSLG Q9Y3P2_HUMAN Q9Y3P2_HUMAN ------------------------------------------------------------ B7Z2S1_HUMAN B7Z2S1_HUMAN ------------------------------------------------------------ H6ST2_HUMAN H6ST2_HUMAN ALPACAVREFEPPRQPERGAPVRTTCPRRHSRVEAELAASRPGSVAASVRAGPPRGVSHG B7Z2U5_HUMAN B7Z2U5_HUMAN ------------------------------------------------------------ H6ST2_DANRE H6ST2_DANRE ------------------------------------------------------------ Q4RPA2_TETNG Q4RPA2_TETNG ------------------------------------------------------------ H6S1B_DANRE H6S1B_DANRE ------------------------------------------------------------ Q4RMN6_TETNG Q4RMN6_TETNG ------------------------------------------------------------ H6ST1_HUMAN H6ST1_HUMAN ------------------------------------------------------------ H6ST1_CRIGR H6ST1_CRIGR ------------------------------------------------------------ H6ST1_MOUSE H6ST1_MOUSE ------------------------------------------------------------ B0S6C9_DANRE B0S6C9_DANRE ------------------------------------------------------------ H6S1A_DANRE H6S1A_DANRE ------------------------------------------------------------ H6ST1_CHICK H6ST1_CHICK ------------------------------------------------------------ A4IHG8_XENTR A4IHG8_XENTR ------------------------------------------------------------ Q8UWB1_XENLA Q8UWB1_XENLA ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

B0S4Y4_DANRE B0S4Y4_DANRE ------------------------------------------------------------ H6ST3_DANRE H6ST3_DANRE ------------------------------------------------------------ Q4S0B1_TETNG Q4S0B1_TETNG ------------------------------------------------------------ Q4TGL7_TETNG Q4TGL7_TETNG -----------------------------------------------------LDAGIRG Q3UTM4_MOUSE Q3UTM4_MOUSE ------------------------------------------------------------ B3KX95_HUMAN B3KX95_HUMAN ------------------------------------------------------------ H6ST3_HUMAN H6ST3_HUMAN ------------------------------------------------------------ Q148Q1_MOUSE Q148Q1_MOUSE ------------------------------------------------------------ H6ST3_MOUSE H6ST3_MOUSE ------------------------------------------------------------ Q149R8_MOUSE Q149R8_MOUSE ------------------------------------------------------------ H6ST2_CHICK H6ST2_CHICK ------------------------------------------------------------ B7Z5H6_HUMAN B7Z5H6_HUMAN ------------------------------------------------------------ B1AUS3_MOUSE B1AUS3_MOUSE FNSPPLQDKPPKAFSSLAGALRAPLFALLPRGRRRRMHDLRRRWDLGSLCRALLTRGLAA H6ST2_MOUSE H6ST2_MOUSE FNSPPLQDKPPKAFSSLAGALRAPLFALLPRGRRRRMHDLRRRWDLGSLCRALLTRGLAA Q9Y3P2_HUMAN Q9Y3P2_HUMAN ------------------------------------------------------------ B7Z2S1_HUMAN B7Z2S1_HUMAN ------------------------------------------------------------ H6ST2_HUMAN H6ST2_HUMAN FHTRPLLDKPRKASSSLAGAACAPLFALLSRGRRRRMHVLRRRWDLGSLCRALLTRGLAA B7Z2U5_HUMAN B7Z2U5_HUMAN ------------------------------------------------------------ H6ST2_DANRE H6ST2_DANRE ------------------------------------------------------------ Q4RPA2_TETNG Q4RPA2_TETNG ------------------------------------------------------------ H6S1B_DANRE H6S1B_DANRE ------------------------------------------------------------ Q4RMN6_TETNG Q4RMN6_TETNG ------------------------------------------------------------ H6ST1_HUMAN H6ST1_HUMAN ------------------------------------------------------------ H6ST1_CRIGR H6ST1_CRIGR ------------------------------------------------------------ H6ST1_MOUSE H6ST1_MOUSE ------------------------------------------------------------ B0S6C9_DANRE B0S6C9_DANRE ------------------------------------------------------------ H6S1A_DANRE H6S1A_DANRE ------------------------------------------------------------ H6ST1_CHICK H6ST1_CHICK ------------------------------------------------------------ A4IHG8_XENTR A4IHG8_XENTR ------------------------------------------------------------ Q8UWB1_XENLA Q8UWB1_XENLA ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

B0S4Y4_DANRE B0S4Y4_DANRE -------------------------MNDKPNKWIFIPIL--------AILFVMIGYQYVC H6ST3_DANRE H6ST3_DANRE -------------------------MNDKPNKWIFIPIL--------AILFVMIGYQYVC Q4S0B1_TETNG Q4S0B1_TETNG -------------------------MDDRSSKLLLVPIL--------AVLFVMIGYQYIC Q4TGL7_TETNG Q4TGL7_TETNG RPTRMQIFRSWAGGHPSAMILGFGHILQRSADIVWGLRSRDMSFCPESVLFVMIGYQYIC Q3UTM4_MOUSE Q3UTM4_MOUSE -------------------------MDERFNKWLLTPVL--------TLLFVVIMYQYVS B3KX95_HUMAN B3KX95_HUMAN ------------------------------------------------------------ H6ST3_HUMAN H6ST3_HUMAN -------------------------MDERFNKWLLTPVL--------TLLFVVIMYQYVS Q148Q1_MOUSE Q148Q1_MOUSE -------------------------MDERFNKWLLTPVL--------TLLFVVIMYQYVS H6ST3_MOUSE H6ST3_MOUSE -------------------------MDERFNKWLLTPVL--------TFLFVVIMYQYVS Q149R8_MOUSE Q149R8_MOUSE ------------------------------------------------------------ H6ST2_CHICK H6ST2_CHICK -------------------------MEDRSHKVLLALVM--------LFLFAVIVLQYVC B7Z5H6_HUMAN B7Z5H6_HUMAN ------------------------MLLKHNGK---------------LLLFYLLSYQALA B1AUS3_MOUSE B1AUS3_MOUSE VGHSLKHVLSAIFSKIFGPLASVGNMDEKSNKLLLALVM--------LFLFAVIVLQYVC H6ST2_MOUSE H6ST2_MOUSE VGHSLKHVLSAIFSKIFGPLASVGNMDEKSNKLLLALVM--------LFLFAVIVLQYVC Q9Y3P2_HUMAN Q9Y3P2_HUMAN --------------------------------------M--------LFLFAVIVLQYVC B7Z2S1_HUMAN B7Z2S1_HUMAN -------------------------MDEKSNKLLLALVM--------LFLFAVIVLQYVC H6ST2_HUMAN H6ST2_HUMAN LGHSLKHVLGAIFSKIFGPMASVGNMDEKSNKLLLALVM--------LFLFAVIVLQYVC B7Z2U5_HUMAN B7Z2U5_HUMAN --------------------------------------M--------LFLFAVIVLQYVC H6ST2_DANRE H6ST2_DANRE -----------------------MDGKSNYSRLLIALLM--------ILFFGGIVLQYIC Q4RPA2_TETNG Q4RPA2_TETNG -------------------------------RLLAVLVL--------VLLFGVMLVQYIC H6S1B_DANRE H6S1B_DANRE ------------------MNDTERNMVERTSKFLLIVVG--------SVFFMLILYQYVA Q4RMN6_TETNG Q4RMN6_TETNG ----------------------GRNMVERSSKFLLIVVG--------SVCFMLILYQYVA H6ST1_HUMAN H6ST1_HUMAN ---------------MRRRRAGGRTMVERASKFVLVVAG--------SVCFMLILYQYAG H6ST1_CRIGR H6ST1_CRIGR -------------------------MVERASKFVLVVAG--------SACFMLILYQYAG H6ST1_MOUSE H6ST1_MOUSE ---------------MRRRRAGGRTMVERASKFVLVVAG--------SACFMLILYQYAG B0S6C9_DANRE B0S6C9_DANRE -----------------MNLLTGRNMVERSSKFLFIVVG--------SVLFMLILYQYVA H6S1A_DANRE H6S1A_DANRE -----------------MNLLTGRNMVERSSKFLFIVVG--------SVLFMLILYQYVA H6ST1_CHICK H6ST1_CHICK ------------------MKRAGRTMVERTSKFLLIVAA--------SVCFMLILYQYVG A4IHG8_XENTR A4IHG8_XENTR ------------------MKCVGRTMVERTSKFLLILVG--------SVFFMLILYQYVG Q8UWB1_XENLA Q8UWB1_XENLA ------------------------------------------------------------ MATCH CONSENSUS ??????????????????????????????????????????????????F??I??QY??

B0S4Y4_DANRE B0S4Y4_DANRE PAGGQACHFRTGDKLVRIAPL--------------------------------------- H6ST3_DANRE H6ST3_DANRE PAGGQACHFRTGDKLVRIAPL--------------------------------------- Q4S0B1_TETNG Q4S0B1_TETNG PAGSHSCHFKAGEKFRGVSLL--------------------------------------- Q4TGL7_TETNG Q4TGL7_TETNG PAGSHSCHFKAGEKFRGVSLL--------------------------------------- Q3UTM4_MOUSE Q3UTM4_MOUSE -PSCTSSCTNFGEQLRSGEARPPAVPSPARRAQAPLDEWERRPQLPPPPRGPPEGSRGVA B3KX95_HUMAN B3KX95_HUMAN ------------------------------------------------------------ H6ST3_HUMAN H6ST3_HUMAN -PSCTSSCTNFGEQPRAGEAGPPAVPGPARRAQAPPEEWERRPQLPPPPRGPPEGPRGAA Q148Q1_MOUSE Q148Q1_MOUSE -PSCTSSCTNFGEQLRSGEARPPAVPSPARRAQAPLDEWERRPQLPPPPRGPPEGSRGVA H6ST3_MOUSE H6ST3_MOUSE -PSCTSSCTNFGEQLRSGEARPPAVPSPARRAQAPLDEWERRPQLPPPPRGPPEGSRGVA Q149R8_MOUSE Q149R8_MOUSE ------------------------------------------------------------ H6ST2_CHICK H6ST2_CHICK -PGTECQLLRL------------------------------------------------- B7Z5H6_HUMAN B7Z5H6_HUMAN ------------------------------------------------------------ B1AUS3_MOUSE B1AUS3_MOUSE -PGTECQLLRLQA---FSSPV--------------------------------------- H6ST2_MOUSE H6ST2_MOUSE -PGTECQLLRLQA---FSSPV--------------------------------------- Q9Y3P2_HUMAN Q9Y3P2_HUMAN -PGTECQLLRLQA---FSSPV--------------------------------------- B7Z2S1_HUMAN B7Z2S1_HUMAN -PGTECQLLRLQA---FSSPV--------------------------------------- H6ST2_HUMAN H6ST2_HUMAN -PGTECQLLRLQA---FSSPV--------------------------------------- B7Z2U5_HUMAN B7Z2U5_HUMAN -PGTECQLLRLQA---FSSPV--------------------------------------- H6ST2_DANRE H6ST2_DANRE STSDWQLLHLASLSSRLGSRAPG------------------------------------- Q4RPA2_TETNG Q4RPA2_TETNG -PGRSECPVLHQLGSWFREPG--------------------------------------- H6S1B_DANRE H6S1B_DANRE -PGVIN----------FGSPH--------------------------------------- Q4RMN6_TETNG Q4RMN6_TETNG -PGVIS----------FSSPH--------------------------------------- H6ST1_HUMAN H6ST1_HUMAN -PGLS-----------LGAPG--------------------------------------- H6ST1_CRIGR H6ST1_CRIGR -PGLS-----------LGAPG--------------------------------------- H6ST1_MOUSE H6ST1_MOUSE -PGLS-----------LGAPG--------------------------------------- B0S6C9_DANRE B0S6C9_DANRE -PGMMN----------FGSPH--------------------------------------- H6S1A_DANRE H6S1A_DANRE -PGMMN----------FGSPH--------------------------------------- H6ST1_CHICK H6ST1_CHICK -PGLS-----------LGAPS--------------------------------------- A4IHG8_XENTR A4IHG8_XENTR -PGMN-----------LGSPS--------------------------------------- Q8UWB1_XENLA Q8UWB1_XENLA ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

B0S4Y4_DANRE B0S4Y4_DANRE ----------------ATPDPTTDDLYREQDPEEDNPPKCASKFNFTERDLTRDVDFNIK H6ST3_DANRE H6ST3_DANRE ----------------ATPDPTTDDLYREQDPEEDNPPKCASKFNFTERDLTRDVDFNIK Q4S0B1_TETNG Q4S0B1_TETNG ---------------STPTFQDSDDFYRDQDLEDDSPPRAPSKFNFTERDLDRHVEFNIK Q4TGL7_TETNG Q4TGL7_TETNG ---------------STPTFQDSDDFYRDQDLEDDSPPRAPSKFNFTERDLDRHVEFNIK Q3UTM4_MOUSE Q3UTM4_MOUSE APEDEDEDPGDPEE-EEEEEEEEPDPEA---PENGSLPRFVPRFNFTLKDLTRFVDFNIK B3KX95_HUMAN B3KX95_HUMAN ------------------------------------------------------------ H6ST3_HUMAN H6ST3_HUMAN APEEEDEEPGDPREGEEEEEEDEPDPEA---PENGSLPRFVPRFNFSLKDLTRFVDFNIK Q148Q1_MOUSE Q148Q1_MOUSE APEDEDEDPGDPEE-EEEEEEEEPDPEA---PENGSLPRFVPRFNFTLKDLTRFVDFNIK H6ST3_MOUSE H6ST3_MOUSE APEDEDEDPGDPEE-EEEEEEEEPDPEA---PENGSLPRFVPRFNFTLKDLTRFVDFNIK Q149R8_MOUSE Q149R8_MOUSE ------------------------------------------------------------ H6ST2_CHICK H6ST2_CHICK ---------------RALSPAAAADPYR---AEDETPARFVPRFNFSAGDLLRRVDFNIK B7Z5H6_HUMAN B7Z5H6_HUMAN ------------------------------------------------------------ B1AUS3_MOUSE B1AUS3_MOUSE -----------------------PDPYR---SEDESSARFVPRYNFSRGDLLRKVDFDIK H6ST2_MOUSE H6ST2_MOUSE -----------------------PDPYR---SEDESSARFVPRYNFSRGDLLRKVDFDIK Q9Y3P2_HUMAN Q9Y3P2_HUMAN -----------------------PDPYR---SEDESSARFVPRYNFTRGDLLRKVDFDIK B7Z2S1_HUMAN B7Z2S1_HUMAN -----------------------PDPYR---SEDESSARFVPRYNFTRGDLLRKVDFDIK H6ST2_HUMAN H6ST2_HUMAN -----------------------PDPYR---SEDESSARFVPRYNFTRGDLLRKVDFDIK B7Z2U5_HUMAN B7Z2U5_HUMAN -----------------------PDPYR---SEDESSARFVPRYNFTRGDLLRKVDFDIK H6ST2_DANRE H6ST2_DANRE ---------------DRLNGAGAGDPYS---SEDGALVRFVPRFNFTTKDLSRAVDFHIK Q4RPA2_TETNG Q4RPA2_TETNG ---------------RETQDSLLRDPYI---AEDGALVRFVPRFNFSKADLNRVVDFNIN H6S1B_DANRE H6S1B_DANRE ---------------GYLLGEEDMTIFP---TPD---PHYVKKYYFPIKDLERKIDFEIK Q4RMN6_TETNG Q4RMN6_TETNG ---------------GYFTEEDEGDIFP---TPD---PHYVKKYYFPVRDLERTVDFQIK H6ST1_HUMAN H6ST1_HUMAN ---------------GRAP-PDDLDLFP---TPD---PHYEKKYYFPVRELERSLRFDMK H6ST1_CRIGR H6ST1_CRIGR ---------------GRAP-PDDLDLFP---TPD---PHYEKKYYFPVRELERSLRFDMK H6ST1_MOUSE H6ST1_MOUSE ---------------GRVP-PDDLDLFP---TPD---PHYEKKYYFPVRELERSLRFDMK B0S6C9_DANRE B0S6C9_DANRE ---------------GYML-EDDADLFP---TPD---PHYVKKFYFPIRDLERTVDFEIK H6S1A_DANRE H6S1A_DANRE ---------------GYML-EDDADLFP---TPD---PHYVKKFYFPIRDLERTVDFEIK H6ST1_CHICK H6ST1_CHICK ----------------GRPYAEEPDLFP---TPD---PHYVKKYYFPVRELERELAFDMK A4IHG8_XENTR A4IHG8_XENTR ---------------RYY--QEDIDLFP---TPD---PHYVKKYFFPVRDLDRSLTFDMK Q8UWB1_XENLA Q8UWB1_XENLA ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????D????????????????????F????L?R???F??K

B0S4Y4_DANRE B0S4Y4_DANRE GDDVIVFLHIQKTGGTTFGRHLVRNIRLEQPCDCKAGQKKCTCHRPGKQESWLFSRFSTG H6ST3_DANRE H6ST3_DANRE GDDVIVFLHIQKTGGTTFGRHLVRNIRLEQPCDCKAGQKKCTCHRPGKQESWLFSRFSTG Q4S0B1_TETNG Q4S0B1_TETNG GDDVIVFLHIQKTGGTTFGRHLVRNIRLEQPCDCKQGQKKCTCHRPGKEESWLFSRFSTG Q4TGL7_TETNG Q4TGL7_TETNG GDDVIVFLHIQKTGGTLFGRHLVRNIRLEQPCDCKQGQKKCTCHRPGKEESWLFSRFSTG Q3UTM4_MOUSE Q3UTM4_MOUSE GRDVIVFLHIQKTGGTTFGRHLVKNIRLEQPCSCKAGQKKCTCHRPGKKETWLFSRFSTG B3KX95_HUMAN B3KX95_HUMAN ------------------------------------------------------------ H6ST3_HUMAN H6ST3_HUMAN GRDVIVFLHIQKTGGTTFGRHLVKNIRLEQPCSCKAGQKKCTCHRPGKKETWLFSRFSTG Q148Q1_MOUSE Q148Q1_MOUSE GRDVIVFLHIQKTGGTTFGRHLVKNIRLEQPCSCKAGQKKCTCHRPGKKETWLFSRFSTG H6ST3_MOUSE H6ST3_MOUSE GRDVIVFLHIQKTGGTTFGRHLVKNIRLEQPCSCKAGQKKCTCHRPGKKETWLFSRFSTG Q149R8_MOUSE Q149R8_MOUSE ------------------------------------------------------------ H6ST2_CHICK H6ST2_CHICK GDDLIVFLHIQKTGGTTFGRHLVRNIQLEQPCECRAGQKKCTCHRPGKRETWLFSRFSTG B7Z5H6_HUMAN B7Z5H6_HUMAN -------------------------------------------------SDWFYCSFNR- B1AUS3_MOUSE B1AUS3_MOUSE GDDLIVFLHIQKTGGTTFGRHLVRNIQLEQPCECRVGQKKCTCHRPGKRETWLFSRFSTG H6ST2_MOUSE H6ST2_MOUSE GDDLIVFLHIQKTGGTTFGRHLVRNIQLEQPCECRVGQKKCTCHRPGKRETWLFSRFSTG Q9Y3P2_HUMAN Q9Y3P2_HUMAN GDDLIVFLHIQKTGGTTFGRHLVRNIQLEQPCECRVGQKKCTCHRPGKRETWLFSRFSTG B7Z2S1_HUMAN B7Z2S1_HUMAN GDDLIVFLHIQKTGGTTFGRHLVRNIQLEQPCECRVGQKKCTCHRPGKRETWLFSRFSTG H6ST2_HUMAN H6ST2_HUMAN GDDLIVFLHIQKTGGTTFGRHLVRNIQLEQPCECRVGQKKCTCHRPGKRETWLFSRFSTG B7Z2U5_HUMAN B7Z2U5_HUMAN GDDLIVFLHIQKTGGTTFGRHLVRNIQLEQPCECRVGQKKCTCHRPGKRETWLFSRFSTG H6ST2_DANRE H6ST2_DANRE GDDVIVFLHIQKTGGTTFGRHLVRNIQLERPCECHAGQKKCTCYRPGKRDTWLFSRFSTG Q4RPA2_TETNG Q4RPA2_TETNG GDDVIVFLHIQKTGGTTFGRHLVRNIKLERPCDCRAGQKKCTCYRPGKKETWLFSRFSTG H6S1B_DANRE H6S1B_DANRE GEDVIVFLHIQKTGGTTFGRHLVQNVRLELPCDCRPGQKKCTCYRPNRKETWLFSRFSTG Q4RMN6_TETNG Q4RMN6_TETNG GEDVIVFLHIQKTGGTTFGRHLVQNVRLEVPCDCRPGQKKCTCYRPNRKETWLFSRFSTG H6ST1_HUMAN H6ST1_HUMAN GDDVIVFLHIQKTGGTTFGRHLVQNVRLEVPCDCRPGQKKCTCYRPNRRETWLFSRFSTG H6ST1_CRIGR H6ST1_CRIGR GDDVIVFLHIQKTGGTTFGRHLVQNVRLEVPCDCRPGQKKCTCYRPNRRETWLFSRFSTG H6ST1_MOUSE H6ST1_MOUSE GDDVIVFLHIQKTGGTTFGRHLVQNVRLEVPCDCRPGQKKCTCYRPNRRETWLFSRFSTG B0S6C9_DANRE B0S6C9_DANRE GDDVIVFLHIQKTGGTTFGRHLVQNVRLEVPCDCRPGQKKCTCYRPNRKETWLFSRFSTG H6S1A_DANRE H6S1A_DANRE GDDVIVFLHIQKTGGTTFGRHLVQNVRLEVPCDCRPGQKKCTCYRPNRKETWLFSRFSTG H6ST1_CHICK H6ST1_CHICK GEDVIVFLHIQKTGGTTFGRHLVQNVRLEVPCDCRPGQKKCTCYRPNRRETWLFSRFSTG A4IHG8_XENTR A4IHG8_XENTR GDDVIVFLHIQKTGGTTFGRHLVQNVRLEVPCDCRPGQKKCTCYRPNRKETWLFSRFSTG Q8UWB1_XENLA Q8UWB1_XENLA ------------------------------------------CYRPNRKETWLFSRFSTG MATCH CONSENSUS G?D?IVFLHIQKTGGTTFGRHLV?N??LE?PC?C??GQKKCTC?RP???E?WLFSRFSTG

B0S4Y4_DANRE B0S4Y4_DANRE WSCGLHADWTELTNCVPVIMDKRQPPKRKR------------------------------ H6ST3_DANRE H6ST3_DANRE WSCGLHADWTELTNCVPVIMDKRQPPKRKRN----------------------------- Q4S0B1_TETNG Q4S0B1_TETNG WSCGLHADWTELTNCVPVIMDKKEAQRNMSGVVSQPQEAGQTLEWSKPMCEEVSSQRGKD Q4TGL7_TETNG Q4TGL7_TETNG WSCGLHADWTELTNCVPVIMDKKEAQRN-------------------------------- Q3UTM4_MOUSE Q3UTM4_MOUSE WSCGLHADWTELTNCVPAIMEKKDCPRNHSHTRYCPASVGFLNP---------------- B3KX95_HUMAN B3KX95_HUMAN -------------------MEKKDCPRNHSHTR--------------------------- H6ST3_HUMAN H6ST3_HUMAN WSCGLHADWTELTNCVPAIMEKKDCPRNHSHTR--------------------------- Q148Q1_MOUSE Q148Q1_MOUSE WSCGLHADWTELTNCVPAIMEKKDCPRNHSHTR--------------------------- H6ST3_MOUSE H6ST3_MOUSE WSCGLHADWTELTNCVPAIMEKKDCPRNHSHTR--------------------------- Q149R8_MOUSE Q149R8_MOUSE -------------------MEKKDCPRNHSHTR--------------------------- H6ST2_CHICK H6ST2_CHICK WSCGLHADWTELTNCVPSVVDSKKEVRLRPSR---------------------------- B7Z5H6_HUMAN B7Z5H6_HUMAN WR----------------IFQILDAARN-------------------------------- B1AUS3_MOUSE B1AUS3_MOUSE WSCGLHADWTELTSCVPAVVDGKRDARLRPSRWRIFQILDGTSKDRWGSSNFNSGANSPS H6ST2_MOUSE H6ST2_MOUSE WSCGLHADWTELTSCVPAVVDGKRDARLRPSR---------------------------- Q9Y3P2_HUMAN Q9Y3P2_HUMAN WSCGLHADWTELTSCVPSVVDGKRDARLRPSRWRIFQILDAASKDKRGSPNTNAGANSPS B7Z2S1_HUMAN B7Z2S1_HUMAN WSCGLHADWTELTSCVPSVVDGKRDARLRPSRWRIFQILDAASKDKRGSPNTNAGANSPS H6ST2_HUMAN H6ST2_HUMAN WSCGLHADWTELTSCVPSVVDGKRDARLRPSR---------------------------- B7Z2U5_HUMAN B7Z2U5_HUMAN WSCGLHADWTELTSCVPSVVDGKRDARLRPSRWRIFQILDAASKDKRGSPNTNAGANSPS H6ST2_DANRE H6ST2_DANRE WSCGLHADWTELTNCVPSFMSNRESQERRMTPSR-------------------------- Q4RPA2_TETNG Q4RPA2_TETNG WSCGLHADWTELTSCVPSRMDSVEVLENLSSR---------------------------- H6S1B_DANRE H6S1B_DANRE WSCGLHADWTELTNCVPGVLNKRESKSKKMRK---------------------------- Q4RMN6_TETNG Q4RMN6_TETNG WSCGLHADWTELTNCVPGVLNKKENKQKNLRPRKVKGSRIRFPSSSSDGMLMGVKRGLPG H6ST1_HUMAN H6ST1_HUMAN WSCGLHADWTELTNCVPGVLDRRDSAALRTPR---------------------------- H6ST1_CRIGR H6ST1_CRIGR WSCGLHADWTELTNCVPGVLDRRDPAGLRSPR---------------------------- H6ST1_MOUSE H6ST1_MOUSE WSCGLHADWTELTNCVPGVLDRRDPAGLRSPR---------------------------- B0S6C9_DANRE B0S6C9_DANRE WSCGLHADWTELTNCVPGVLNKKESRMKNQ------------------------------ H6S1A_DANRE H6S1A_DANRE WSCGLHADWTELTNCVPGVLNKKESRMK-NQR---------------------------- H6ST1_CHICK H6ST1_CHICK WSCGLHADWTELTNCVPGVLGRRESAPNRTPRK--------------------------- A4IHG8_XENTR A4IHG8_XENTR WSCGLHADWTELTSCVPGVLDKKETSMKIKR----------------------------- Q8UWB1_XENLA Q8UWB1_XENLA WSCGLHADWTELTSCVPGVLGNKEINIKRK------------------------------ MATCH . CONSENSUS WSCGLHADWTELT?CVP???????????????????????????????????????????

B0S4Y4_DANRE B0S4Y4_DANRE ------------N----------------------------------------------- H6ST3_DANRE H6ST3_DANRE ------------------------------------------------------------ Q4S0B1_TETNG Q4S0B1_TETNG DSSRRAFI---------------------------------------------------- Q4TGL7_TETNG Q4TGL7_TETNG ------------------------------------------------------------ Q3UTM4_MOUSE Q3UTM4_MOUSE ------------------------------------------------------------ B3KX95_HUMAN B3KX95_HUMAN ------------N----------------------------------------------- H6ST3_HUMAN H6ST3_HUMAN ------------N----------------------------------------------- Q148Q1_MOUSE Q148Q1_MOUSE ------------N----------------------------------------------- H6ST3_MOUSE H6ST3_MOUSE ------------N----------------------------------------------- Q149R8_MOUSE Q149R8_MOUSE ------------N----------------------------------------------- H6ST2_CHICK H6ST2_CHICK ------------N----------------------------------------------- B7Z5H6_HUMAN B7Z5H6_HUMAN ------------------------------------------------------------ B1AUS3_MOUSE B1AUS3_MOUSE STKPRSTSKSGKN----------------------------------------------- H6ST2_MOUSE H6ST2_MOUSE ------------N----------------------------------------------- Q9Y3P2_HUMAN Q9Y3P2_HUMAN STKTRNTSKSGKN----------------------------------------------- B7Z2S1_HUMAN B7Z2S1_HUMAN STKTRNTSKSGKN----------------------------------------------- H6ST2_HUMAN H6ST2_HUMAN ------------N----------------------------------------------- B7Z2U5_HUMAN B7Z2U5_HUMAN STKTRNTSKSGKN----------------------------------------------- H6ST2_DANRE H6ST2_DANRE ------------N----------------------------------------------- Q4RPA2_TETNG Q4RPA2_TETNG ------------N----------------------------------------------- H6S1B_DANRE H6S1B_DANRE ------------------------------------------------------------ Q4RMN6_TETNG Q4RMN6_TETNG GNHSKEGWRSLINTLAGCQGADCQRAGNRSSVSSPHRFGRGFLEKQVHPSTVCLILHLVV H6ST1_HUMAN H6ST1_HUMAN ------------K----------------------------------------------- H6ST1_CRIGR H6ST1_CRIGR ------------K----------------------------------------------- H6ST1_MOUSE H6ST1_MOUSE ------------K----------------------------------------------- B0S6C9_DANRE B0S6C9_DANRE ------------------------------------------------------------ H6S1A_DANRE H6S1A_DANRE ------------K----------------------------------------------- H6ST1_CHICK H6ST1_CHICK ------------------------------------------------------------ A4IHG8_XENTR A4IHG8_XENTR ------------K----------------------------------------------- Q8UWB1_XENLA Q8UWB1_XENLA ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

B0S4Y4_DANRE B0S4Y4_DANRE -----------------------------FYYIT-------MLRDPVSRY--LSEWKHVQ H6ST3_DANRE H6ST3_DANRE -----------------------------FYYIT-------MLRDPVSRY--LSEWKHVQ Q4S0B1_TETNG Q4S0B1_TETNG -----------------------------LYRVHGTSTTSPCCVNPVSRY--LSEWKHVQ Q4TGL7_TETNG Q4TGL7_TETNG ------------------------------------------------------------ Q3UTM4_MOUSE Q3UTM4_MOUSE -----------------------------TPFPQ-------VLTPPVPRRAPLAVWQWLS B3KX95_HUMAN B3KX95_HUMAN -----------------------------FYYIT-------MLRDPVSRY--LSEWKHVQ H6ST3_HUMAN H6ST3_HUMAN -----------------------------FYYIT-------MLRDPVSRY--LSEWKHVQ Q148Q1_MOUSE Q148Q1_MOUSE -----------------------------FYYIT-------MLRDPVSRY--LSEWKHVQ H6ST3_MOUSE H6ST3_MOUSE -----------------------------FYYIT-------MLRDPVSRY--LSEWKHVQ Q149R8_MOUSE Q149R8_MOUSE -----------------------------FYYIT-------MLRDPVSRY--LSEWKHVQ H6ST2_CHICK H6ST2_CHICK -----------------------------FYYIT-------ILRDPVSRY--LSEWRHVQ B7Z5H6_HUMAN B7Z5H6_HUMAN -----------------------------FHYIT-------ILRDPVSRY--LSEWRHVQ B1AUS3_MOUSE B1AUS3_MOUSE -----------------------------FHYIT-------ILRDPVSRY--LSEWRHVQ H6ST2_MOUSE H6ST2_MOUSE -----------------------------FHYIT-------ILRDPVSRY--LSEWRHVQ Q9Y3P2_HUMAN Q9Y3P2_HUMAN -----------------------------FHYIT-------ILRDPVSRY--LSEWRHVQ B7Z2S1_HUMAN B7Z2S1_HUMAN -----------------------------FHYIT-------ILRDPVSRY--LSEWRHVQ H6ST2_HUMAN H6ST2_HUMAN -----------------------------FHYIT-------ILRDPVSRY--LSEWRHVQ B7Z2U5_HUMAN B7Z2U5_HUMAN -----------------------------FHYIT-------ILRDPVSRY--LSEWRHVQ H6ST2_DANRE H6ST2_DANRE -----------------------------YYYIT-------ILRDPVWRY--LSEWRHVQ Q4RPA2_TETNG Q4RPA2_TETNG -----------------------------YYYIT-------ILRDPVSRY--LSEWRHVQ H6S1B_DANRE H6S1B_DANRE -----------------------------FYYIT-------LLRDPVSRY--LSEWRHVQ Q4RMN6_TETNG Q4RMN6_TETNG HFEVLTRFFPPDLHGREESLARTEALEVKFYYIT-------LLRDPVSRY--LSEWRHVQ H6ST1_HUMAN H6ST1_HUMAN -----------------------------FYYIT-------LLRDPVSRY--LSEWRHVQ H6ST1_CRIGR H6ST1_CRIGR -----------------------------FYYIT-------LLRDPVSRY--LSEWRHVQ H6ST1_MOUSE H6ST1_MOUSE -----------------------------FYYIT-------LLRDPVSRY--LSEWRHVQ B0S6C9_DANRE B0S6C9_DANRE ------------------------------------------------------------ H6S1A_DANRE H6S1A_DANRE -----------------------------FYYIT-------LLRDPVSRY--LSEWRHVQ H6ST1_CHICK H6ST1_CHICK -----------------------------FYYIT-------LLRDPVSRY--LSEWRHVQ A4IHG8_XENTR A4IHG8_XENTR -----------------------------FYYIT-------LLRDPVSRY--LSEWRHVQ Q8UWB1_XENLA Q8UWB1_XENLA -----------------------------FYYIT-------LLRDPVSRY--LSEWRHVQ MATCH CONSENSUS ?????????????????????????????F?YIT????????LRDPVSRY??LSEW?HVQ

B0S4Y4_DANRE B0S4Y4_DANRE RGATWKTSLHMCDGRSPTQDELPTCYNGDDWSGVTLHDFMDCPSNLANNRQVRMLADLSL H6ST3_DANRE H6ST3_DANRE RGATWKTSLHMCDGRSPTQDELPTCYNGDDWSGVTLHDFMDCPSNLANNRQVRMLADLSL Q4S0B1_TETNG Q4S0B1_TETNG RGATWKTALHMCDGRSPTQDELPNCYSGDDWSGVPLTDFMNCPSNLANNRQVRMLADLSL Q4TGL7_TETNG Q4TGL7_TETNG ------------------------------------------------------------ Q3UTM4_MOUSE Q3UTM4_MOUSE KG--WAANL------------------GEG------------------------------ B3KX95_HUMAN B3KX95_HUMAN RGATWKTSLHMCDGRSPTPDELPTCYPGDDWSGVSLREFMDCTYNLANNRQVRMLADLSL H6ST3_HUMAN H6ST3_HUMAN RGATWKTSLHMCDGRSPTPDELPTCYPGDDWSGVSLREFMDCTYNLANNRQVRMLADLSL Q148Q1_MOUSE Q148Q1_MOUSE RGATWKTSLHMCDGRSPTPDELPTCYPGDDWSGVSLREFMDCSYNLANNRQVRMLADLSL H6ST3_MOUSE H6ST3_MOUSE RGATWKTSLHMCDGRSPTPDELPTCYPGDDWSGVSLREFMDCSYNLANNRQVRMLADLSL Q149R8_MOUSE Q149R8_MOUSE RGATWKTSLHMCDGRSPTPDELPTCYPGDDWSGVSLREFMDCSYNLANNRQVRMLADLSL H6ST2_CHICK H6ST2_CHICK RGATWKASLHVCDGRSPTTEELPSCYTGDDWSGCSLQEFMDCPYNLANNRQVRMLSDLSL B7Z5H6_HUMAN B7Z5H6_HUMAN RGATWKASLHVCDGRPPTSEELPSCYTGDDWSGCPLKEFMDCPYNLANNRQVRMLSDLTL B1AUS3_MOUSE B1AUS3_MOUSE RGATWKASLHVCDGRPPTSEELPSCYTGDDWSGCPLKEFMDCPYNLANNRQVRMLSDLTL H6ST2_MOUSE H6ST2_MOUSE RGATWKASLHVCDGRPPTSEELPSCYTGDDWSGCPLKEFMDCPYNLANNRQVRMLSDLTL Q9Y3P2_HUMAN Q9Y3P2_HUMAN RGATWKASLHVCDGRPPTSEELPSCYTGDDWSGCPLKEFMDCPYNLANNRQ--------- B7Z2S1_HUMAN B7Z2S1_HUMAN RGATWKASLHVCDGRPPTSEELPSCYTGDDWSGCPLKEFMDCPYNLANNRQVRMLSDLTL H6ST2_HUMAN H6ST2_HUMAN RGATWKASLHVCDGRPPTSEELPSCYTGDDWSGCPLKEFMDCPYNLANNRQVRMLSDLTL B7Z2U5_HUMAN B7Z2U5_HUMAN RGATWKASLHVCDGRPPTSEELPSCYTGDDWSGCPLKEFMDCPYNLANNRQVRMLSDLTL H6ST2_DANRE H6ST2_DANRE RGATWKASKHMCDGRLPTLTELPSCYPGDDWSGCSLEEFMVCPYNLANNRQTRMLADLSL Q4RPA2_TETNG Q4RPA2_TETNG RGATWKASLHVCDGRSPTLSELPSCYSGDDWSGCSLQEFMDCAYNLANNRQTRMLADLSL H6S1B_DANRE H6S1B_DANRE RGATWKTSLHMCDGRTPTPEELPPCYEGTDWSGCTLQQFMDCPYNLANNRQVRMLADLSL Q4RMN6_TETNG Q4RMN6_TETNG RGATWKTSLHMCDGRTPTPEELPSCYEGSDWSGCTLQQFMDCPYNLANNRQVRMLADLSL H6ST1_HUMAN H6ST1_HUMAN RGATWKTSLHMCDGRTPTPEELPPCYEGTDWSGCTLQEFMDCPYNLANNRQVRMLADLSL H6ST1_CRIGR H6ST1_CRIGR RGATWKTSLHMCDGRTPTPEELPPCYEGTDWSGCTLQEFMDCPYNLANNRQVRMLADLSL H6ST1_MOUSE H6ST1_MOUSE RGATWKTSLHMCDGRTPTPEELPPCYEGTDWSGCTLQEFMDCPYNLANNRQVRMLADLSL B0S6C9_DANRE B0S6C9_DANRE ------------------------------------------------------------ H6S1A_DANRE H6S1A_DANRE RGATWKTSLHMCDGRTPTPEELPPCYEGTDWSGCTLQQFMDCPYNLANNRQVRMLADLSL H6ST1_CHICK H6ST1_CHICK RGATWKTSLHMCDGRTPTPEELPSCYEGTDWSGCTLQEFMDCPYNLANNRQVRMLADLSL A4IHG8_XENTR A4IHG8_XENTR RGATWKTSLHMCDGRTPTPEELPSCYEGTDWSGCTLQEFMECPYNLANNRQVRMLADLSL Q8UWB1_XENLA Q8UWB1_XENLA RGATWKTSLHMCDGRTPTPEELPSCYEGTDWSGCTLQEFMECPYNLANNRQVRMLADLSL MATCH CONSENSUS RGATWK?SLH?CDGR?PT??ELP?CY?G?DWSG??L??FM?C?YNLANNRQVRML?DL?L

B0S4Y4_DANRE B0S4Y4_DANRE VGCYNLSTMNESERNPILLASAKSNLKNMAFYGLTEFQRKTQYLFERTFHLRFISAFTQI H6ST3_DANRE H6ST3_DANRE VGCYNLSTMNESERNPILLASAKSNLKNMAFYGLTEFQRKTQYLFERTFHLRFISAFTQI Q4S0B1_TETNG Q4S0B1_TETNG VGCYNLSSTNESQRNHILLSSAMSNLKNMAFFGLTEFQRKTQYLFERTFSLRFISAFTQI Q4TGL7_TETNG Q4TGL7_TETNG ------------------------------------------------------------ Q3UTM4_MOUSE Q3UTM4_MOUSE ------------------------------------------------------------ B3KX95_HUMAN B3KX95_HUMAN VGCYNLTFMNESERNTILLQSAKNNLKNMAFFGLTEFQRKTQFLFERTFNLKFISPFTQF H6ST3_HUMAN H6ST3_HUMAN VGCYNLTFMNESERNTILLQSAKNNLKNMAFFGLTEFQRKTQFLFERTFNLKFISPFTQF Q148Q1_MOUSE Q148Q1_MOUSE VGCYNLTFMNESERNTILLQSAKNNLKNMAFFGLTEFQRKTQFLFERTFNLKFISPFTQF H6ST3_MOUSE H6ST3_MOUSE VGCYNLTFMNESERNTILLQSAKNNLKNMAFFGLTEFQRKTQFLFERTFNLKFISPFTQF Q149R8_MOUSE Q149R8_MOUSE VGCYNLTFMNESERNTILLQSAKNNLKNMAFFGLTEFQRKTQFLFERTFNLKFISPFTQF H6ST2_CHICK H6ST2_CHICK VGCYNLSVMPEEQRNKVLLDSAKENLKRMAFFGLTEFQRKTQYLFEKTFNMNFISPFTQY B7Z5H6_HUMAN B7Z5H6_HUMAN VGCYNLSVMPEKQRNKVLLESAKSNLKHMAFFGLTEFQRKTQYLFEKTFNMNFISPFTQY B1AUS3_MOUSE B1AUS3_MOUSE VGCYNLSVMPEKQRNKVLLESAKSNLKHMAFFGLTEFQRKTQYLFEKTFNMNFISPFTQY H6ST2_MOUSE H6ST2_MOUSE VGCYNLSVMPEKQRNKVLLESAKSNLKHMAFFGLTEFQRKTQYLFEKTFNMNFISPFTQY Q9Y3P2_HUMAN Q9Y3P2_HUMAN CAC--------------------------------------------------------- B7Z2S1_HUMAN B7Z2S1_HUMAN VGCYNLSVMPEKQRNKVLLESAKSNLKHMAFFGLTEFQRKTQYLFEKTFNMNFISPFTQY H6ST2_HUMAN H6ST2_HUMAN VGCYNLSVMPEKQRNKVLLESAKSNLKHMAFFGLTEFQRKTQYLFEKTFNMNFISPFTQY B7Z2U5_HUMAN B7Z2U5_HUMAN VGCYNLSVMPEKQRNKVLLESAKSNLKHMAFFGLTEFQRKTQYLFEKTFNMNFISPFTQY H6ST2_DANRE H6ST2_DANRE VGCYNLTVMSENQRWAMLLESAKRNLRNMAFFGLTEYQRKTQYLFEHTFRLSFIAPFTQL Q4RPA2_TETNG Q4RPA2_TETNG VGCYNVSAMSEEARWAVLLESAKRNLRSMAFFGLTEYQRKTQYLFERTFHLEFITPFTQV H6S1B_DANRE H6S1B_DANRE VGCYNLSTVPEKRRSQLLLESAKKNLRDMAFYGLTEFQRKTQYLFERTFHLKFIRPFMQY Q4RMN6_TETNG Q4RMN6_TETNG VGCYNMSTVPEKKRAQLLLESAKKNLRDMAFFGLTEYQRKTQFLFERTFRLRFIRPFMQY H6ST1_HUMAN H6ST1_HUMAN VGCYNLSFIPEGKRAQLLLESAKKNLRGMAFFGLTEFQRKTQYLFERTFNLKFIRPFMQY H6ST1_CRIGR H6ST1_CRIGR VGCYNLSFIPESKRAQLLLESAKKNLRGMAFFGLTEFQRKTQYLFERTFNLKFIRPFMQY H6ST1_MOUSE H6ST1_MOUSE VGCYNLSFIPESKRAQLLLESAKKNLRGMAFFGLTEFQRKTQYLFERTFNLKFIRPFMQY B0S6C9_DANRE B0S6C9_DANRE ------------------------------------------------------------ H6S1A_DANRE H6S1A_DANRE VGCYNMSFIPEKKRAQVLLESAKKNLRDMAFFGLTEFQRKTQYLFERTFRLKFIRPFMQY H6ST1_CHICK H6ST1_CHICK VGCYNMSFIPENKRAQILLESAKKNLKDMAFFGLTEFQRKTQYLFERTFNLKFIRPFMQY A4IHG8_XENTR A4IHG8_XENTR VGCYNMSFYPDNKRAQVLLESAKKNLKDMAFFGLTEFQRKTQYLFERTFNLKFIRPFMQY Q8UWB1_XENLA Q8UWB1_XENLA VGCYNMSFLQDSKRAQVLLESAKKNLKD-------------------------------- MATCH CONSENSUS VGCYN?????E??R???LL?SAK?NL??MAF?GLTE?QRKTQ?LFE?TF???FI??F?Q?

B0S4Y4_DANRE B0S4Y4_DANRE NSTRAANVELRDNMRSRIEQLNMLDMQLYEFAKDLFLQRYQFVRQRERQEERLKRREERR H6ST3_DANRE H6ST3_DANRE NSTRAANVELRDDMRSRIEQLNMLDMQLYEFAKDLFLQRYQFVRQRERQEERLKRREERR Q4S0B1_TETNG Q4S0B1_TETNG NSTRASNVDLSEPVRQRIEELNFLDVQLYEYAKDLFLQRFQFTRQREHQEVRLKRREERR Q4TGL7_TETNG Q4TGL7_TETNG ------------------------------------------------------------ Q3UTM4_MOUSE Q3UTM4_MOUSE ------------------------------------------------------------ B3KX95_HUMAN B3KX95_HUMAN NITRASNVEINEGARQRIEDLNFLDMQLYEYAKDLFQQRYHHTKQLEHQRDRQKRREERR H6ST3_HUMAN H6ST3_HUMAN NITRASNVEINEGARQRIEDLNFLDMQLYEYAKDLFQQRYHHTKQLEHQRDRQKRREERR Q148Q1_MOUSE Q148Q1_MOUSE NITRASNVDINDGARQHIEELNFLDMQLYEYAKDLFQQRYHHTKQLEHQRDRQKRREERR H6ST3_MOUSE H6ST3_MOUSE NITRASNVDINDGARQHIEELNFLDMQLYEYAKDLFQQRYHHTKQLEHQRDRQKRREERR Q149R8_MOUSE Q149R8_MOUSE NITRASNVDINDGARQHIEELNFLDMQLYEYAKDLFQQRYHHTKQLEHQRDRQKRREERR H6ST2_CHICK H6ST2_CHICK NSTRASSVEIDEQTQQRIEALNFLDMELYDYAKDLFLQRYQYMRQKEHQEARRKRQEQRK B7Z5H6_HUMAN B7Z5H6_HUMAN NTTRASSVEINEEIQKRIEGLNFLDMELYSYAKDLFLQRYQFMRQKEHQEARRKRQEQRK B1AUS3_MOUSE B1AUS3_MOUSE NTTRASSVEINEEIQKRIEGLNFLDMELYSYAKDLFLQRYQFMRQKEHQDARRKRQEQRK H6ST2_MOUSE H6ST2_MOUSE NTTRASSVEINEEIQKRIEGLNFLDMELYSYAKDLFLQRYQFMRQKEHQDARRKRQEQRK Q9Y3P2_HUMAN Q9Y3P2_HUMAN ------------------------------------------------------------ B7Z2S1_HUMAN B7Z2S1_HUMAN NTTRASSVEINEEIQKRIEGLNFLDMELYSYAKDLFLQRYQFMRQKEHQEARRKRQEQRK H6ST2_HUMAN H6ST2_HUMAN NTTRASSVEINEEIQKRIEGLNFLDMELYSYAKDLFLQRYQFMRQKEHQEARRKRQEQRK B7Z2U5_HUMAN B7Z2U5_HUMAN NTTRASSVEINEEIQKRIEGLNFLDMELYSYAKDLFLQRYQFMRQKEHQEARRKRQEQRK H6ST2_DANRE H6ST2_DANRE NGTRAASVEVEPETQRRIRELNQWDVELYEYARDLFLQRFQFARQQERREARQRRIQERR Q4RPA2_TETNG Q4RPA2_TETNG NGTRASSVEVPPKTQQRILQLNHWDLELYEYARDLFLQRFQVARQQERRQARERRQQERR H6S1B_DANRE H6S1B_DANRE NSTRAAGVDLDNDTIQRIEELNDLDMKLYDYAKDLFQQRYQYKHMLDRREQR-------- Q4RMN6_TETNG Q4RMN6_TETNG NSTRAAGVDLDNTTVQRIEELNELDMELYDYAKDLFQQRYQYTRQQERRQQRIKNHMQ-L H6ST1_HUMAN H6ST1_HUMAN NSTRAGGVEVDEDTIRRIEELNDLDMQLYDYAKDLFQQRYQYKRQLERREQRLRSREERL H6ST1_CRIGR H6ST1_CRIGR NSTRAGGVEVDEDTIRHIEELNDLDMQLYDYAKDLFQQRYQYKRQLERREQRLRNREERL H6ST1_MOUSE H6ST1_MOUSE NSTRAGGVEVDEDTIRHIEELNDLDMQLYDYAKDLFQQRYQYKRQLERREQRLRNREERL B0S6C9_DANRE B0S6C9_DANRE ------------------------------------------------------------ H6S1A_DANRE H6S1A_DANRE NSTRAAGVDLDNDTIQRIEELNDLDMQLYDYARDLFQQRYMYKRQLERREQRLKNQPLFP H6ST1_CHICK H6ST1_CHICK NSTRAGGVEVDNDTIRRIEELNDLDMQLYDYAKDLFQQRYQYKRQLERMEQRIKNREERL A4IHG8_XENTR A4IHG8_XENTR NNTRAGGVDLDNDTIQRIEELNDLDMQLYDYAKDLFQQRYQFKRQMERMEQRKKNREERL Q8UWB1_XENLA Q8UWB1_XENLA ------------------------------------------------------------ MATCH CONSENSUS N?TRA??V?????????I??LN??D??LY??A?DLF?QR?????Q?E????R????????

B0S4Y4_DANRE B0S4Y4_DANRE WIRER---------RVNQSKEPIVENQTRV------------------------------ H6ST3_DANRE H6ST3_DANRE WIRER---------RVNQSKEPIVENQTRVTT---------------------------- Q4S0B1_TETNG Q4S0B1_TETNG WLRGQ--------------KEQSP------------------------------------ Q4TGL7_TETNG Q4TGL7_TETNG ------------------------------------------------------------ Q3UTM4_MOUSE Q3UTM4_MOUSE ------------------------------------------------------------ B3KX95_HUMAN B3KX95_HUMAN LQREH---------RDHQWPKEDGAAEG-------------------------------- H6ST3_HUMAN H6ST3_HUMAN LQREH---------RDHQWPKEDGAAEG-------------------------------- Q148Q1_MOUSE Q148Q1_MOUSE LQREH---------RAHRWPKEDRAMEG-------------------------------- H6ST3_MOUSE H6ST3_MOUSE LQREH---------RAHRWPKEDRAMEG-------------------------------- Q149R8_MOUSE Q149R8_MOUSE LQREH---------RAHRWPKEDRAMEG-------------------------------- H6ST2_CHICK H6ST2_CHICK ILRAK---------QAHLREQGENSS---------------------------------- B7Z5H6_HUMAN B7Z5H6_HUMAN FLKGRLLQTHFQ--SQGQGQSQNPNQNQSQNPNPNANQNLTQNLMQNLTQSLSQKENRES B1AUS3_MOUSE B1AUS3_MOUSE FLKGRFLQTHFQSQSQGQSQSQSPGQNLSQNPNPNPNQNLTQNLSHNLTPSSNPNSTQRE H6ST2_MOUSE H6ST2_MOUSE FLKGRFLQTHFQSQSQGQSQSQSPGQNLSQNPNPNPNQNLTQNLSHNLTPSSNPNSTQRE Q9Y3P2_HUMAN Q9Y3P2_HUMAN ----------------------SPT----------------------------------- B7Z2S1_HUMAN B7Z2S1_HUMAN FLKGRLLQTHFQSQGQGQSQNPNQNSGKEQNDNTSNG----------------------- H6ST2_HUMAN H6ST2_HUMAN FLKGRLLQTHF--QSQGQGQSQNPNQNQSQNPNPNANQNLTQNLMQNLTQS----LSQKE B7Z2U5_HUMAN B7Z2U5_HUMAN FLKGRLLQTHF--QSQGQGQSQNPNQNQSQNPNPNANQNLTQNLMQNLTQS----LSQKE H6ST2_DANRE H6ST2_DANRE KLRAKVKSWLGVTGKAVFKPTKEPPMTEQSPAFAEEKQADAERTLESETEGQVEENWLEE Q4RPA2_TETNG Q4RPA2_TETNG RLRGRF------------------------------------------------------ H6S1B_DANRE H6S1B_DANRE LLRGH---------ASFHSPFREDGAGGEGTA---------------------------- Q4RMN6_TETNG Q4RMN6_TETNG SHQGL---------GINLWPSHSRQSLASKLEDGQREEEGDEGGRTEEVGN--------- H6ST1_HUMAN H6ST1_HUMAN LHRAK---------EALPREDADEPG---------------------------------- H6ST1_CRIGR H6ST1_CRIGR LHRSK---------EALPREDTEEPG---------------------------------- H6ST1_MOUSE H6ST1_MOUSE LHRSK---------EALPREDPEEPG---------------------------------- B0S6C9_DANRE B0S6C9_DANRE ------------------------------------------------------------ H6S1A_DANRE H6S1A_DANRE FRRTS---------SSDSTFRDDAPESEGS------------------------------ H6ST1_CHICK H6ST1_CHICK LHRSN---------EALPKEETEEQG---------------------------------- A4IHG8_XENTR A4IHG8_XENTR LHRSN---------EAFSKEEAEDQV---------------------------------- Q8UWB1_XENLA Q8UWB1_XENLA ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

B0S4Y4_DANRE B0S4Y4_DANRE ---TT----------------TEDYASQV-VRW- H6ST3_DANRE H6ST3_DANRE ---------------------TEDYASQV-VRW- Q4S0B1_TETNG Q4S0B1_TETNG ---------------------------------- Q4TGL7_TETNG Q4TGL7_TETNG ---------------------------------- Q3UTM4_MOUSE Q3UTM4_MOUSE ---------------------------------- B3KX95_HUMAN B3KX95_HUMAN ---TV----------------TEDYNSQV-VRW- H6ST3_HUMAN H6ST3_HUMAN ---TV----------------TEDYNSQV-VRW- Q148Q1_MOUSE Q148Q1_MOUSE ---TV----------------TEDYNSQV-VRW- H6ST3_MOUSE H6ST3_MOUSE ---TV----------------TEDYNSQV-VRW- Q149R8_MOUSE Q149R8_MOUSE ---TV----------------TEDYNSQV-VRW- H6ST2_CHICK H6ST2_CHICK ---------------------STDYLGNV-ERWR B7Z5H6_HUMAN B7Z5H6_HUMAN PKQNS-----GKEQNDNTSNGTNDYIGSV-EKWR B1AUS3_MOUSE B1AUS3_MOUSE NRGSQKQGSGQGQGDSGTSNGTNDYIGSV-ETWR H6ST2_MOUSE H6ST2_MOUSE NRGSQKQGSGQGQGDSGTSNGTNDYIGSV-ETWR Q9Y3P2_HUMAN Q9Y3P2_HUMAN ---------------------------------- B7Z2S1_HUMAN B7Z2S1_HUMAN ---------------------TNDYIGSV-EKWR H6ST2_HUMAN H6ST2_HUMAN NRESPKQNSGKEQNDN-TSNGTNDYIGSV-EKWR B7Z2U5_HUMAN B7Z2U5_HUMAN NRESPKQNSGKEQNDN-TSNGTNDYIGSV-EKWR H6ST2_DANRE H6ST2_DANRE DDGEI----------------MLDYLENV-EQWR Q4RPA2_TETNG Q4RPA2_TETNG ---------------------------------- H6S1B_DANRE H6S1B_DANRE --RLP----------------TEDYMNHIINGW- Q4RMN6_TETNG Q4RMN6_TETNG --RLP----------------TEDYMNQIIHRW- H6ST1_HUMAN H6ST1_HUMAN --RVP----------------TEDYMSHIIEKW- H6ST1_CRIGR H6ST1_CRIGR --RVP----------------TEDYMSHIIEKW- H6ST1_MOUSE H6ST1_MOUSE --RVP----------------TEDYMSHIIEKW- B0S6C9_DANRE B0S6C9_DANRE ---------------------------------- H6S1A_DANRE H6S1A_DANRE --RLP----------------TEDYMNHIINRW- H6ST1_CHICK H6ST1_CHICK --RLP----------------TEDYMSHIIEKW- A4IHG8_XENTR A4IHG8_XENTR --RWP----------------TEDYMSHIIEKW- Q8UWB1_XENLA Q8UWB1_XENLA ---------------------------------- MATCH CONSENSUS ??????????????????????????????????


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