Alignment of the gene Family HBG098487 of HOVERGEN

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Isoforms are ON
GUC2D_RAT GUC2D_RAT AGLQQGCHPEGQDWTAPHWKTCRALPGPRG Q4TAT8_TETNG Q4TAT8_TETNG ------------------------------ P79999_ORYLA P79999_ORYLA ------------------------------ Q7T2Q2_ORYLA Q7T2Q2_ORYLA ------------------------------ A2BFQ0_DANRE A2BFQ0_DANRE --MNDHTSFLCQSHHPRWQTQSSAGKRRRK Q4S8Y6_TETNG Q4S8Y6_TETNG ------------------------------ P87343_ORYLA P87343_ORYLA TNHRDTCRLHNLAYHPPWWHSTTKMKRNKD Q9W616_ORYLA Q9W616_ORYLA TNHRDSCRLHNLAYHPPWWHSTTKMKRNKD Q4T7P7_TETNG Q4T7P7_TETNG ------------------------------ Q7T3I2_ORYLA Q7T3I2_ORYLA ----MVVVWSEMPHQGAALSSKPPSHTPP- Q9W615_ORYLA Q9W615_ORYLA ----MVVVWSEMPHQGAALSSKPPSHTPP- O57480_CHICK O57480_CHICK ------------------------------ GUC2E_RAT GUC2E_RAT -----MSAWLLPAGGFPGAGFCIPAWQ--- Q8C8X5_MOUSE Q8C8X5_MOUSE -----MSAWLLPAGGLPGAGFCVPARQ--- B1ASX7_MOUSE B1ASX7_MOUSE -----MSAWLLPAGGLPGAGFCVPARQ--- GUC2E_MOUSE GUC2E_MOUSE -----MSAWLLPAGGLPGARFCVPARQ--- GUC2D_HUMAN GUC2D_HUMAN -----MTACARRAGGLPDPGLCGPAWWAPS GUC2D_BOVIN GUC2D_BOVIN -----MTACTFLAGGLRDPGLCGPTRWAP- GUC2D_CANFA GUC2D_CANFA -----MSACALLAGGLPDPRLCAPARWAR- GUC2F_BOVIN GUC2F_BOVIN ------------MFLAPWPFSHLMLWFV-- GUC2F_HUMAN GUC2F_HUMAN ------------MFLGLGRFSRLVLWFA-- GUC2F_MOUSE GUC2F_MOUSE ------------MFLGPWPFSRLLSWFA-- GUC2F_RAT GUC2F_RAT ------------MFLGPWPFSRLLSWFA-- Q9PUK0_RANPI Q9PUK0_RANPI ---------------MRTPDYCNVKKKKK- B3DHF2_DANRE B3DHF2_DANRE -----MRHIHLPFGGALWQFSSYPCCP--- Q4SY29_TETNG Q4SY29_TETNG ------------------------------ P87342_ORYLA P87342_ORYLA ----------MQHISPNGWESNHPCVS--- Q9W614_ORYLA Q9W614_ORYLA ----------MQHISPNGWESNHPCVS--- MATCH CONSENSUS ??????????????????????????????

GUC2D_RAT GUC2D_RAT L-------TVRHLRTVSSIS---------- Q4TAT8_TETNG Q4TAT8_TETNG ------------------------------ P79999_ORYLA P79999_ORYLA ------------------------------ Q7T2Q2_ORYLA Q7T2Q2_ORYLA ------------------------------ A2BFQ0_DANRE A2BFQ0_DANRE QSSSQKSETPASPVSSSPVL---------- Q4S8Y6_TETNG Q4S8Y6_TETNG ------------------------------ P87343_ORYLA P87343_ORYLA TRTTSSSEGCRQLKTLSALLLTSSLSKPQL Q9W616_ORYLA Q9W616_ORYLA TRTTSSSEGCRQLKTLSALLLTSSLSKPQL Q4T7P7_TETNG Q4T7P7_TETNG ------------------------------ Q7T3I2_ORYLA Q7T3I2_ORYLA --------ALTSVLSLSPGP---------- Q9W615_ORYLA Q9W615_ORYLA --------ALTSVLSLSPGP---------- O57480_CHICK O57480_CHICK ------------------------------ GUC2E_RAT GUC2E_RAT --------SRSSLSRVLRWP---------- Q8C8X5_MOUSE Q8C8X5_MOUSE --------SPSSFSRVLRWP---------- B1ASX7_MOUSE B1ASX7_MOUSE --------SPSSFSRVLRWP---------- GUC2E_MOUSE GUC2E_MOUSE --------SPSSFSRVLRWP---------- GUC2D_HUMAN GUC2D_HUMAN --------LPRLPRALPRLP---------- GUC2D_BOVIN GUC2D_BOVIN --------SPPGLPPIPPRP---------- GUC2D_CANFA GUC2D_CANFA --------SPPGVPGAPPWP---------- GUC2F_BOVIN GUC2F_BOVIN --------TLGRQRGQHGLA---------- GUC2F_HUMAN GUC2F_HUMAN --------AFRKLLGHHGLA---------- GUC2F_MOUSE GUC2F_MOUSE --------ISSRLSGQHGLP---------- GUC2F_RAT GUC2F_RAT --------ISSRLSGQHGLT---------- Q9PUK0_RANPI Q9PUK0_RANPI --------KLARAEFGTRKS---------- B3DHF2_DANRE B3DHF2_DANRE --------VLRSRRSLSTLP---------- Q4SY29_TETNG Q4SY29_TETNG ----------------MALP---------- P87342_ORYLA P87342_ORYLA --------IERNRRTLQSLP---------- Q9W614_ORYLA Q9W614_ORYLA --------IERNRRTLQSLP---------- MATCH CONSENSUS ??????????????????????????????

GUC2D_RAT GUC2D_RAT ------VFSVVFWGVLLWA--DSLSLPAWA Q4TAT8_TETNG Q4TAT8_TETNG -----------------------------A P79999_ORYLA P79999_ORYLA -----------MMHFCFLLVCPCLLSITSV Q7T2Q2_ORYLA Q7T2Q2_ORYLA -----------MMHFCFLLVCPCLLSITSV A2BFQ0_DANRE A2BFQ0_DANRE ------RSHSWWGNCFLLPLVMLSYFPCEA Q4S8Y6_TETNG Q4S8Y6_TETNG -------------------------LPCQA P87343_ORYLA P87343_ORYLA PFSSMHLFRSWKEKLSLLFLFIISFFPCQI Q9W616_ORYLA Q9W616_ORYLA PFSSMHLFRSWKEKLSLLFLFIISFFPCQI Q4T7P7_TETNG Q4T7P7_TETNG -------------------LLSLCILPSLV Q7T3I2_ORYLA Q7T3I2_ORYLA ------APKHTLLRLLLLLLPPLCLLPCSA Q9W615_ORYLA Q9W615_ORYLA ------APKHTLLRLLLLLLPPLCLLPCSA O57480_CHICK O57480_CHICK ------------------------------ GUC2E_RAT GUC2E_RAT -----------GPGLPGLLLLLLLPSPSAF Q8C8X5_MOUSE Q8C8X5_MOUSE -----------RPGLPGLLLLLLLPSPSAL B1ASX7_MOUSE B1ASX7_MOUSE -----------RPGLPGLLLLLLLPSPSAL GUC2E_MOUSE GUC2E_MOUSE -----------RPGLPGLLLLLLLPSPSAL GUC2D_HUMAN GUC2D_HUMAN -----------------LLLLLLLLQPPAL GUC2D_BOVIN GUC2D_BOVIN -----------RLRLR-PPLLLLLLLPRSV GUC2D_CANFA GUC2D_CANFA -----------QPRLRLLLLLLLLP-PSAL GUC2F_BOVIN GUC2F_BOVIN ----------SFKLLWCLWLLVLMSLPLQV GUC2F_HUMAN GUC2F_HUMAN ----------SAKFLWCLCLLSVMSLPQQV GUC2F_MOUSE GUC2F_MOUSE ----------SSKFLRCLCLLALLPLLRWG GUC2F_RAT GUC2F_RAT ----------SSKFLRYLCLLALLPL---I Q9PUK0_RANPI Q9PUK0_RANPI ------------------------------ B3DHF2_DANRE B3DHF2_DANRE -----------FYSITLWIILGVLTFPRCV Q4SY29_TETNG Q4SY29_TETNG -----------FYNLLLWVLLGAFTFPCCV P87342_ORYLA P87342_ORYLA -----------FYNIMLWLLLGVLTFPCCV Q9W614_ORYLA Q9W614_ORYLA -----------FYNIMLWLLLGVLTFPCCV MATCH CONSENSUS ??????????????????????????????

GUC2D_RAT GUC2D_RAT ----RETFTLGVLGPWDCDPIFAQALPSMA Q4TAT8_TETNG Q4TAT8_TETNG W---SATFKIALVGPWSCDPMFSRAMATAA P79999_ORYLA P79999_ORYLA H---AATFKLALVGPWSCDPMFSRAMPSAA Q7T2Q2_ORYLA Q7T2Q2_ORYLA H---AATFKLALVGPWSCDPMFSRAMPSAA A2BFQ0_DANRE A2BFQ0_DANRE W---GTTFKIAIVGPWACDPMYSKALPDLA Q4S8Y6_TETNG Q4S8Y6_TETNG W---ATTFKVALIGPWTCDLLYSKALPDLA P87343_ORYLA P87343_ORYLA W---ATTFKVALVGPWTCDLLYSKALPDLA Q9W616_ORYLA Q9W616_ORYLA W---ATTFKVALVGPWTCDLLYSKALPDLA Q4T7P7_TETNG Q4T7P7_TETNG E---AAWFRVGVVGPWECDPLFAKALPHVA Q7T3I2_ORYLA Q7T3I2_ORYLA E---AAWFRVGVVGPWGCDPIFAKALPSTA Q9W615_ORYLA Q9W615_ORYLA E---AAWFRVGVVGPWGCDPIFAKALPSTA O57480_CHICK O57480_CHICK ---------VGVLGPWLCDPVASRALPELA GUC2E_RAT GUC2E_RAT ----SAVFKVGVLGPWACDPIFARARPDLA Q8C8X5_MOUSE Q8C8X5_MOUSE ----SAVFKVGVLGPWACDPIFARARPDLA B1ASX7_MOUSE B1ASX7_MOUSE ----SAVFKVGVLGPWACDPIFARARPDLA GUC2E_MOUSE GUC2E_MOUSE ----SAVFKVGVLGPWACDPIFARARPDLA GUC2D_HUMAN GUC2D_HUMAN ----SAVFTVGVLGPWACDPIFSRARPDLA GUC2D_BOVIN GUC2D_BOVIN L---SAVFTVGVLGPWACDPIFARARPDLA GUC2D_CANFA GUC2D_CANFA ----SAVFTVGVLGPWACDPIFARARPDLA GUC2F_BOVIN GUC2F_BOVIN W---APPYKIGVVGPWTCDPLFSKALPEIA GUC2F_HUMAN GUC2F_HUMAN W---TLPYKIGVVGPWACDSLFSKALPEVA GUC2F_MOUSE GUC2F_MOUSE Q---ALPYKIGVIGPWTCDPFFSKALPEVA GUC2F_RAT GUC2F_RAT WWGQALPYKIGVIGPWTCDPFFSKALPEVA Q9PUK0_RANPI Q9PUK0_RANPI ----PMTHRYSWLTRWITK----------- B3DHF2_DANRE B3DHF2_DANRE Q---CLVFKVGIIGPWNCDPNYAKSLPAIA Q4SY29_TETNG Q4SY29_TETNG R---CLIFKVGVLGPWNCDPVYHRAFPAAA P87342_ORYLA P87342_ORYLA H---CLIFKVGVLGPWNCDPVYYRALPTVA Q9W614_ORYLA Q9W614_ORYLA H---CLIFKVGVLGPWNCDPVYYRALPTVA MATCH . : * . CONSENSUS ?????????????GPW?CDP????A?P??A

GUC2D_RAT GUC2D_RAT TQLAVDRVNQDASLLLGSQLDFKILPTGCD Q4TAT8_TETNG Q4TAT8_TETNG ANLALLRIQSDSSLSRGYHYSVKLLEEDCS P79999_ORYLA P79999_ORYLA ANLALSRLRSDADLSRGFWYDVKLLNEDCS Q7T2Q2_ORYLA Q7T2Q2_ORYLA ANLALSRLRSDADLSRGFWYDVKLLNEDCS A2BFQ0_DANRE A2BFQ0_DANRE ARLAMSRINKDPELNKGYWYDYTVINEDCS Q4S8Y6_TETNG Q4S8Y6_TETNG ARLATSRINKDPDLNKGYWYDYTLINEDCK P87343_ORYLA P87343_ORYLA ARLAISRINKNPYLNRGYWYDYALVNEDCK Q9W616_ORYLA Q9W616_ORYLA ARLAISRINKNPYLNRGYWYDYALVNEDCK Q4T7P7_TETNG Q4T7P7_TETNG AQLAVNRINRDPSLSYAATFDYIVLQEPCE Q7T3I2_ORYLA Q7T3I2_ORYLA AQLAITHINRDPSLSSAGAFDFAVLQEPCE Q9W615_ORYLA Q9W615_ORYLA AQLAITHINRDPSLSSAGAFDFAVLQEPCE O57480_CHICK O57480_CHICK SRLAVARLNRDPELSRGYWWDAVLLPEPCQ GUC2E_RAT GUC2E_RAT ARLATDRLNRDLALDGGPWFEVTLLPEPCL Q8C8X5_MOUSE Q8C8X5_MOUSE ARLAANRLNRDFALDGGPRFEVALLPEPCL B1ASX7_MOUSE B1ASX7_MOUSE ARLAANRLNRDFALDGGPRFEVALLPEPCL GUC2E_MOUSE GUC2E_MOUSE ARLAANRLNRDFGLDGGPRFEVALLPEPCL GUC2D_HUMAN GUC2D_HUMAN ARLAAARLNRDPGLAGGPRFEVALLPEPCR GUC2D_BOVIN GUC2D_BOVIN ARLAASRLNHAAALEGGPRFEVALLPEPCR GUC2D_CANFA GUC2D_CANFA ARLAAARLNRDAALEDGPRFEVTLLPEPCR GUC2F_BOVIN GUC2F_BOVIN AQLATERINKDPALDLGHSLEYVIFNEDCQ GUC2F_HUMAN GUC2F_HUMAN ARLAIERINRDPSFDLSYSFEYVILNEDCQ GUC2F_MOUSE GUC2F_MOUSE AALAIERISRDKTFDRSYSFEYVILNEDCQ GUC2F_RAT GUC2F_RAT AALAIERISRDMSFDRSYSFEYVILNEDCQ Q9PUK0_RANPI Q9PUK0_RANPI -----------------FWRKT------VK B3DHF2_DANRE B3DHF2_DANRE SRLAVGRINNDFSLDLGCTMDFVILQEACE Q4SY29_TETNG Q4SY29_TETNG AKLAGSRMNRDPSLDLGLEMEFVTLQEPCE P87342_ORYLA P87342_ORYLA ARLAISRINRDPNLDLGLTMDFIILQEPCE Q9W614_ORYLA Q9W614_ORYLA ARLAISRINRDPNLDLGLTMDFIILQEPCE MATCH . CONSENSUS A?LA??R???D??L????????????E?C?

GUC2D_RAT GUC2D_RAT TPH------------------------ALA Q4TAT8_TETNG Q4TAT8_TETNG LSKGPEPLASADRPAAAPTSLLLCFLPALT P79999_ORYLA P79999_ORYLA ASK------------------------ALT Q7T2Q2_ORYLA Q7T2Q2_ORYLA ASK------------------------ALT A2BFQ0_DANRE A2BFQ0_DANRE SSR------------------------GLA Q4S8Y6_TETNG Q4S8Y6_TETNG SSR------------------------ALA P87343_ORYLA P87343_ORYLA STR------------------------ALV Q9W616_ORYLA Q9W616_ORYLA STR------------------------ALV Q4T7P7_TETNG Q4T7P7_TETNG TSR------------------------ALE Q7T3I2_ORYLA Q7T3I2_ORYLA TSR------------------------ALE Q9W615_ORYLA Q9W615_ORYLA TSR------------------------ALE O57480_CHICK O57480_CHICK TPQ------------------------AVT GUC2E_RAT GUC2E_RAT TPG------------------------SLG Q8C8X5_MOUSE Q8C8X5_MOUSE TPG------------------------SLG B1ASX7_MOUSE B1ASX7_MOUSE TPG------------------------SLG GUC2E_MOUSE GUC2E_MOUSE TPG------------------------SLG GUC2D_HUMAN GUC2D_HUMAN TPG------------------------SLG GUC2D_BOVIN GUC2D_BOVIN TPG------------------------SLG GUC2D_CANFA GUC2D_CANFA TPG------------------------SLG GUC2F_BOVIN GUC2F_BOVIN ASR------------------------ALS GUC2F_HUMAN GUC2F_HUMAN TSR------------------------ALS GUC2F_MOUSE GUC2F_MOUSE TSK------------------------ALA GUC2F_RAT GUC2F_RAT TSK------------------------ALT Q9PUK0_RANPI Q9PUK0_RANPI PPK------------------------ALM B3DHF2_DANRE B3DHF2_DANRE TSK------------------------ALT Q4SY29_TETNG Q4SY29_TETNG TSK------------------------ALN P87342_ORYLA P87342_ORYLA TSK------------------------AHT Q9W614_ORYLA Q9W614_ORYLA TSK------------------------ALT MATCH . . CONSENSUS ????????????????????????????L?

GUC2D_RAT GUC2D_RAT TFVAHRNTVAAFIGPVNPGYCPAAALLAQG Q4TAT8_TETNG Q4TAT8_TETNG GLGDMEGYGHVYIGPFNPMLCGAAALFAQH P79999_ORYLA P79999_ORYLA ELGEMEGYGHAYIGPFNPALCHAASLMAQH Q7T2Q2_ORYLA Q7T2Q2_ORYLA ELGEMEGYGHAYIGPFNPALCHAASLMAQH A2BFQ0_DANRE A2BFQ0_DANRE RFAELEGYGSAFLGPANPGYCTAATLLAKN Q4S8Y6_TETNG Q4S8Y6_TETNG RFAELEGYGAAYLGPANPGYCSSAALYAKE P87343_ORYLA P87343_ORYLA RFSDLEGYGAAFLGPANPGYCSSAALYTKE Q9W616_ORYLA Q9W616_ORYLA RFSDLEGYGAAFLGPANPGYCSSAALYTKE Q4T7P7_TETNG Q4T7P7_TETNG AFLGFHTKAAGYIGPANAGYCDAASMLSKG Q7T3I2_ORYLA Q7T3I2_ORYLA TFVGFHTKASGYIGPVNPGYCDAASMLTKG Q9W615_ORYLA Q9W615_ORYLA TFVGFHTKASGYIGPVNPGYCDAASMLTKG O57480_CHICK O57480_CHICK ALLGAERYAAGLVGPLNPAVCGAAELLAAA GUC2E_RAT GUC2E_RAT AVSSALTRVSGLVGPVNPAACRPAELLAQE Q8C8X5_MOUSE Q8C8X5_MOUSE AVSSALSRVSGLVGPVNPAACRPAELLAQE B1ASX7_MOUSE B1ASX7_MOUSE AVSSALSRVSGLVGPVNPAACRPAELLAQE GUC2E_MOUSE GUC2E_MOUSE AVSSALSRVSGLVGPVNPAGCRPAELLAQE GUC2D_HUMAN GUC2D_HUMAN AVSSALARVSGLVGPVNPAACRPAELLAEE GUC2D_BOVIN GUC2D_BOVIN AVSSALTRVSGLVGPVNPAACRPAELLAQE GUC2D_CANFA GUC2D_CANFA AVSSALGRVSGLVGPVNPAACRPAELLAQE GUC2F_BOVIN GUC2F_BOVIN SFISHHQMASGFIGPANPGYCEAASLLGNS GUC2F_HUMAN GUC2F_HUMAN SFISHHQMASGFIGPTNPGYCEAASLLGNS GUC2F_MOUSE GUC2F_MOUSE SFISHQQMASGFVGPANPGFCEAASLLGTS GUC2F_RAT GUC2F_RAT SFISHQQMASGFVGPANPGYCEAASLLGNS Q9PUK0_RANPI Q9PUK0_RANPI EFANFDKFSSAFIGPQNPGYCDAASLLGKN B3DHF2_DANRE B3DHF2_DANRE SFVQYENVADAFVGPTNPGYCNAAALMSKN Q4SY29_TETNG Q4SY29_TETNG AFIYYEGMVDAFVGPINPGYCAAASLLSKN P87342_ORYLA P87342_ORYLA TFIYYDKSANAPVGPTNPGYCIAASLLAKS Q9W614_ORYLA Q9W614_ORYLA TFIYSDKSANALVGPTNPGYCIAASLLAKS MATCH . :** *. * .* : CONSENSUS ?????????????GP?NP??C??A?L????

GUC2D_RAT GUC2D_RAT WGKSLFSWAC-----GAPEGGGALVPTLPS Q4TAT8_TETNG Q4TAT8_TETNG WEAGLASPGCLDANWPN-------LPPITP P79999_ORYLA P79999_ORYLA WDAGLASPGCLDPVWLN-------LPPITP Q7T2Q2_ORYLA Q7T2Q2_ORYLA WDAGLASPGCLDPVWLN-------LPPITP A2BFQ0_DANRE A2BFQ0_DANRE WNKGILSWGCLKAEMDE-EMYPTFLRPLPL Q4S8Y6_TETNG Q4S8Y6_TETNG WDVGLLSWGCLNPNMKKVGMYPTYLQPLPL P87343_ORYLA P87343_ORYLA WDVGILSWGCLKPYMKTVDMFPTLLRPLPL Q9W616_ORYLA Q9W616_ORYLA WDVGILSWGCLKPYMKTVDMFPTFLRPLPL Q4T7P7_TETNG Q4T7P7_TETNG WNKAVFPWGCVGYELDDLRSHPTFAHSMPR Q7T3I2_ORYLA Q7T3I2_ORYLA WNKAVFPWACVGYDLDDVRSHPTLARSLPR Q9W615_ORYLA Q9W615_ORYLA WNKAVFPWACVGYELDDVRSHPTLARSLPR O57480_CHICK O57480_CHICK WNKPLVSWSCVG---DGEGERETLVEPMPA GUC2E_RAT GUC2E_RAT AGVALVPWGC-----PGTRAAGTTAPAVTP Q8C8X5_MOUSE Q8C8X5_MOUSE AGVALVPWGC-----PGTRAAGTTAPAVTP B1ASX7_MOUSE B1ASX7_MOUSE AGVALVPWGC-----PGTRAAGTTAPAVTP GUC2E_MOUSE GUC2E_MOUSE AGVALVPWGC-----PGTRAAGTTAPAVTP GUC2D_HUMAN GUC2D_HUMAN AGIALVPWGC-----PWTQAEGTTAPAVTP GUC2D_BOVIN GUC2D_BOVIN AGVALVPWGC-----PGTRAAGTTAPVVTP GUC2D_CANFA GUC2D_CANFA AGVALVPWSC-----PGTRAGGTTAPAGTP GUC2F_BOVIN GUC2F_BOVIN WDKGIFSWACVNYELDSKNSHPTFSRTLPS GUC2F_HUMAN GUC2F_HUMAN WDKGIFSWACVNYELDNKISYPTFSRTLPS GUC2F_MOUSE GUC2F_MOUSE WDKGIFSWACVNHELDNKHSFPTFSRTLPS GUC2F_RAT GUC2F_RAT WDKGIFSWACVNHELDNKHSYPTFSRTLPS Q9PUK0_RANPI Q9PUK0_RANPI WDKAIFSWACINHELDMRDSFPTFARTMPT B3DHF2_DANRE B3DHF2_DANRE WDKSLFSWACVNHELDRVQGYPTFARTLPS Q4SY29_TETNG Q4SY29_TETNG WDKALFSITCVNYELEHTVGFPTFARTLPI P87342_ORYLA P87342_ORYLA WDKALFSFSCISYELDRLTAYPTFARAAPF Q9W614_ORYLA Q9W614_ORYLA WDKALFSFSCISYELDRLTAYPTFARAAPF MATCH : . * . CONSENSUS ?????????C????????????T???????

GUC2D_RAT GUC2D_RAT MADVLLSVMRHFGWARLAIVSSHQDIWVTT Q4TAT8_TETNG Q4TAT8_TETNG PTRVLFTVLRYFGWAHAAVVSAPTDLWEST P79999_ORYLA P79999_ORYLA PSKVLFTVLRFFRWAHVAVASAPTDLWEST Q7T2Q2_ORYLA Q7T2Q2_ORYLA PSKVLFTVLRFFRWAHVAVVSAPTDLWEST A2BFQ0_DANRE A2BFQ0_DANRE SSRVLFSVLRFFRWAHVGIVTAEGDMWEAT Q4S8Y6_TETNG Q4S8Y6_TETNG PSRVLFAVLRYFRWAHVSIISDETDLWEAT P87343_ORYLA P87343_ORYLA SSNVLFTVLRYFRWAHVAIISEDTDLWEAT Q9W616_ORYLA Q9W616_ORYLA SSNVLFTVLRYFRWAHVAIISEDTDLWEAT Q4T7P7_TETNG Q4T7P7_TETNG PTSVLLSVVRYFRWAHIGIISSSDDIWVET Q7T3I2_ORYLA Q7T3I2_ORYLA PTWVLHNLLSYFRWAHIAIISSYEDIWVET Q9W615_ORYLA Q9W615_ORYLA PTWVLHNLLSYFRWAHIAIISSYEDIWVET O57480_CHICK O57480_CHICK PGAVLHAVLSYFRWAHVAVVTAPQDAWREV GUC2E_RAT GUC2E_RAT AADALYVLLKAFRWARVALITAPQDLWVEA Q8C8X5_MOUSE Q8C8X5_MOUSE AADALYVLLRAFRWARVALITAPQDLWVEA B1ASX7_MOUSE B1ASX7_MOUSE AADALYVLLRAFRWARVALITAPQDLWVEA GUC2E_MOUSE GUC2E_MOUSE AADALYVLLRAFRWARVALITAPQDLWVEA GUC2D_HUMAN GUC2D_HUMAN AADALYALLRAFGWARVALVTAPQDLWVEA GUC2D_BOVIN GUC2D_BOVIN AADALYALLRAFRWAHVALVTAPQDLWVEA GUC2D_CANFA GUC2D_CANFA AADALYALLRAFRWARVALITAPQDLWVEA GUC2F_BOVIN GUC2F_BOVIN PIRVLLTVMKYFQWAHAGVISSDEDIWVHT GUC2F_HUMAN GUC2F_HUMAN PIRVLVTVMKYFQWAHAGVISSDEDIWVHT GUC2F_MOUSE GUC2F_MOUSE PIRVLVTVMKYFQWAHAGVISSDEDIWMHT GUC2F_RAT GUC2F_RAT PIRVLVTVMKYFQWAHAGVISSDEDIWVHT Q9PUK0_RANPI Q9PUK0_RANPI PNKVLFLFMKYFRWAHVAVVSSNEDIWVDT B3DHF2_DANRE B3DHF2_DANRE PLRVLFNVLKFFRWANIGIVSSNEDIWIDT Q4SY29_TETNG Q4SY29_TETNG SVDVLFNVLKHFRWANVAVVSSNEDIWRDT P87342_ORYLA P87342_ORYLA PADVLFTVFKHYRWATSVVISSNEEIWIET Q9W614_ORYLA Q9W614_ORYLA PADVLFTVFKHYRWATSVVISSNEEIWIET MATCH .* .. : ** : : : * . CONSENSUS ????L??????F?WA?????????D?W???

GUC2D_RAT GUC2D_RAT AQQLATAFRAHGLPIGLITSLGPGE-KGAT Q4TAT8_TETNG Q4TAT8_TETNG GQEVAAGLRALGLPVGPVVTMERSGKGGAR P79999_ORYLA P79999_ORYLA AQEVASCLRAMGLPVGPVVSMETNSKDGAQ Q7T2Q2_ORYLA Q7T2Q2_ORYLA AQEVASSLRAMGLPVGPVVSMETNSKDGAQ A2BFQ0_DANRE A2BFQ0_DANRE GHELAASLRALGLPVGKVVTMEQDK-EGPR Q4S8Y6_TETNG Q4S8Y6_TETNG GQELAASLRTLGLPVKPVVTMEDGK-EGAR P87343_ORYLA P87343_ORYLA GHELASSLRALGLPVNPVVTMETEK-DGPR Q9W616_ORYLA Q9W616_ORYLA GHELASSLRALGLPVNPVVTMETEK-DGPR Q4T7P7_TETNG Q4T7P7_TETNG ANKVADALRSHGLPVRLVSFMENTP-HAIR Q7T3I2_ORYLA Q7T3I2_ORYLA AIKVADSLRSHGISVRLVSFMENTP-HGIR Q9W615_ORYLA Q9W615_ORYLA AIKVADSLRSHGISVRLVSFMENTP-HGIR O57480_CHICK O57480_CHICK GRGLAQEMRARGPPVTVVTPVGTRE-EEAG GUC2E_RAT GUC2E_RAT GRALSTALRARGLPVALVTSMVPSDLSGAR Q8C8X5_MOUSE Q8C8X5_MOUSE GRALSTALRARGLPVALVTSMETSDRSGAR B1ASX7_MOUSE B1ASX7_MOUSE GRALSTALRARGLPVALVTSMETSDRSGAR GUC2E_MOUSE GUC2E_MOUSE GRALSTALRARGLPVALVTSMETSDRSGAR GUC2D_HUMAN GUC2D_HUMAN GRSLSTALRARGLPVASVTSMEPLDLSGAR GUC2D_BOVIN GUC2D_BOVIN GHALSTALRARGLPVALVTSMEPSDLSGAR GUC2D_CANFA GUC2D_CANFA GRALSAALRARGLPVALVTTMEPSDLSGAR GUC2F_BOVIN GUC2F_BOVIN AYRVASALRSRGLPVGVVLTTGQDS-QSIQ GUC2F_HUMAN GUC2F_HUMAN ANRVASALRSHGLPVGVVLTTGQDS-QSMR GUC2F_MOUSE GUC2F_MOUSE ANRVSSALRSQGLPVGVVLTSGRDS-QSIQ GUC2F_RAT GUC2F_RAT ANQVSSALRSHGLPVGVVLTSGQDS-RSIQ Q9PUK0_RANPI Q9PUK0_RANPI GRKVASALRNQGLPIGIVTNMGNGE-RGLI B3DHF2_DANRE B3DHF2_DANRE AAKLASALRNRGLPVGIVTSMGNND-TMLE Q4SY29_TETNG Q4SY29_TETNG AGRVSTALRDRGLPVSLVTSMGMNK-TEVE P87342_ORYLA P87342_ORYLA AGRVASALRMKGLPVGFVAAMGMND-TELE Q9W614_ORYLA Q9W614_ORYLA AGRVASALRMKGLPVGFVAAMGMND-TELE MATCH . :: :* * .: : CONSENSUS ???????LR??GLPV??V????????????

GUC2D_RAT GUC2D_RAT EVCKQLHSVHGLKIVVLCMHSALLGGLEQT Q4TAT8_TETNG Q4TAT8_TETNG EALKRIQGADRVKVVIMCMSSLLIGGEDQR P79999_ORYLA P79999_ORYLA EALYQVKTADKVNVIIMCMSSVLIGGEHQR Q7T2Q2_ORYLA Q7T2Q2_ORYLA EALYQVKTADKVNVIIMCMSSVLIGGEHQR A2BFQ0_DANRE A2BFQ0_DANRE QALQAIRDTDRVRVVIMCMHSALIGGEEQY Q4S8Y6_TETNG Q4S8Y6_TETNG RALTKVRETDRVRVVIMCMPSVLIGGQTQY P87343_ORYLA P87343_ORYLA SALAKVREADRVRVIIMCMPSVLIGGQAQY Q9W616_ORYLA Q9W616_ORYLA SALAKVREADRVRVIIMCMPSVLIGGQAQY Q4T7P7_TETNG Q4T7P7_TETNG HTLSKVRKMKELRVVILCMHSVLIGGEVQK Q7T3I2_ORYLA Q7T3I2_ORYLA QTLSRVHKMQEIRAVILCMHSALIGGSAQK Q9W615_ORYLA Q9W615_ORYLA QTLSRVHKMQEIRAVILCMHSALIGGSAQK O57480_CHICK O57480_CHICK EALRRVRRADGVRVVVMCMHSVLLGGEEQR GUC2E_RAT GUC2E_RAT EALRRIRDGPRVRVVIMVMHSVLLGGEEQR Q8C8X5_MOUSE Q8C8X5_MOUSE EALGRIRDGPRVRVVIMVMHSVLLGGEEQR B1ASX7_MOUSE B1ASX7_MOUSE EALGRIRDGPRVRVVIMVMHSVLLGGEEQR GUC2E_MOUSE GUC2E_MOUSE EALGRIRDGPRVRVVIMVMHSVLLGGEEQR GUC2D_HUMAN GUC2D_HUMAN EALRKVRDGPRVTAVIMVMHSVLLGGEEQR GUC2D_BOVIN GUC2D_BOVIN EALRRVQDGPRVRAVIMVMHSVLLGGEEQR GUC2D_CANFA GUC2D_CANFA EALRRVQDGPRVRAVIMVMHSVLLGGEEQR GUC2F_BOVIN GUC2F_BOVIN KALQQIRQADRIRIIIMCMHSTLIGGETQT GUC2F_HUMAN GUC2F_HUMAN KALQRIHQADRIRIIIMCMHSALIGGETQM GUC2F_MOUSE GUC2F_MOUSE KALQQIRQADRIRIIIMCMHSALIGGETQT GUC2F_RAT GUC2F_RAT KALQQIRQADRIRIIIMCMHSALIGGETQT Q9PUK0_RANPI Q9PUK0_RANPI DTLTAIRTCMISESSIMCMHSVFIGGEEQA B3DHF2_DANRE B3DHF2_DANRE NTLMSIKNAGDIKVIIMCMHSVLIGGEQQA Q4SY29_TETNG Q4SY29_TETNG SSLRNIQNAGGVRVIIMCMHSVLVGGEQQA P87342_ORYLA P87342_ORYLA STLKKIQSTGGVRVIIMCIDSVLVGGEQQA Q9W614_ORYLA Q9W614_ORYLA STLKKIQSTGGVRVIIMCMHSVLVGGEQQA MATCH :: :: : * ::** * CONSENSUS ??L????????????IM?M?S?L?GG??Q?

GUC2D_RAT GUC2D_RAT VLLRCAREEGLTDGRLVFLPYDTLLFALPY Q4TAT8_TETNG Q4TAT8_TETNG QLLLDALEMGMVSDGYVFIPYDALLYAMPY P79999_ORYLA P79999_ORYLA ELLLTALDMGMISDGYVFIPYDALLYAMPY Q7T2Q2_ORYLA Q7T2Q2_ORYLA ELLLTALDMGMISDGYVFIPYDALLYAMPY A2BFQ0_DANRE A2BFQ0_DANRE QLLTTALEMRMIDRGYIFIPYDTLLYSLPY Q4S8Y6_TETNG Q4S8Y6_TETNG HLLTTALAMRMIDRGYIFIPYDTLLYSLPY P87343_ORYLA P87343_ORYLA QLLTTALAMRMIDRGYVFIPYDTLLYSLPY Q9W616_ORYLA Q9W616_ORYLA QLLTTALAMRMIDRGYVFIPYDTLLYSLPY Q4T7P7_TETNG Q4T7P7_TETNG LLLETAYDMEMIDGSFVFVPYDTLLYSLPY Q7T3I2_ORYLA Q7T3I2_ORYLA LLLEAAYDMKMTDGSLVFVPYDTLLYSLPH Q9W615_ORYLA Q9W615_ORYLA LLLEAAYDMKMTDGSLVFVPYDTLLYSLPH O57480_CHICK O57480_CHICK VLLEKAEDMGMTDGTYVFIPYDALTFPLPY GUC2E_RAT GUC2E_RAT YLLEAAEELGLTDGSLVFLPFDTLHYALSP Q8C8X5_MOUSE Q8C8X5_MOUSE YLLEAAEELALTDGSLVFLPFDTLHYALSP B1ASX7_MOUSE B1ASX7_MOUSE YLLEAAEELALTDGSLVFLPFDTLHYALSP GUC2E_MOUSE GUC2E_MOUSE YLLEAAEELALTDGSLVFLPFDTLHYALSP GUC2D_HUMAN GUC2D_HUMAN YLLEAAEELGLTDGSLVFLPFDTIHYALSP GUC2D_BOVIN GUC2D_BOVIN CLLEAAEELGLADGSLVFLPFDTLHYALSP GUC2D_CANFA GUC2D_CANFA CLLQAAEELGLADGSLVFLPFDTLHYALSP GUC2F_BOVIN GUC2F_BOVIN HLLEWAHDLQMTDGTYVFVPYDTLLYSLPY GUC2F_HUMAN GUC2F_HUMAN HLLECAHDLKMTDGTYVFVPYDALLYSLPY GUC2F_MOUSE GUC2F_MOUSE HFLELAHDLKMTDGTYVFVPYDVLLYSLPY GUC2F_RAT GUC2F_RAT HFLELAHDLKMTDGTYVFVPYDVLLYSLPY Q9PUK0_RANPI Q9PUK0_RANPI IFLIKAHEMGLTDGRYVFVPYDTLLYSLPY B3DHF2_DANRE B3DHF2_DANRE TFLTKAYDMGLASGRYVFIPYDTLLYSLPY Q4SY29_TETNG Q4SY29_TETNG TFLLKAKEMGLTGGQYVFVPYDTLHYSVPY P87342_ORYLA P87342_ORYLA VFLLKAKQLGLTSGKYVFVPYDTLHYSVPY Q9W614_ORYLA Q9W614_ORYLA VFLLKAKQLGLTSGKYVFVPYDTLHYSVPY MATCH :* * : . :*:*:*.: :.:. CONSENSUS ??L??A??????????VF?P?D?L?Y????

GUC2D_RAT GUC2D_RAT -----------------------------R Q4TAT8_TETNG Q4TAT8_TETNG QVTPVLQPPALPVLPGGAESGLSFSFPSNQ P79999_ORYLA P79999_ORYLA -----------------------------Q Q7T2Q2_ORYLA Q7T2Q2_ORYLA -----------------------------Q A2BFQ0_DANRE A2BFQ0_DANRE -----------------------------E Q4S8Y6_TETNG Q4S8Y6_TETNG -----------------------------K P87343_ORYLA P87343_ORYLA -----------------------------K Q9W616_ORYLA Q9W616_ORYLA -----------------------------K Q4T7P7_TETNG Q4T7P7_TETNG -----------------------------R Q7T3I2_ORYLA Q7T3I2_ORYLA -----------------------------R Q9W615_ORYLA Q9W615_ORYLA -----------------------------R O57480_CHICK O57480_CHICK -----------------------------H GUC2E_RAT GUC2E_RAT -----------------------------G Q8C8X5_MOUSE Q8C8X5_MOUSE -----------------------------G B1ASX7_MOUSE B1ASX7_MOUSE -----------------------------G GUC2E_MOUSE GUC2E_MOUSE -----------------------------G GUC2D_HUMAN GUC2D_HUMAN -----------------------------G GUC2D_BOVIN GUC2D_BOVIN -----------------------------G GUC2D_CANFA GUC2D_CANFA -----------------------------G GUC2F_BOVIN GUC2F_BOVIN -----------------------------K GUC2F_HUMAN GUC2F_HUMAN -----------------------------K GUC2F_MOUSE GUC2F_MOUSE -----------------------------K GUC2F_RAT GUC2F_RAT -----------------------------K Q9PUK0_RANPI Q9PUK0_RANPI -----------------------------K B3DHF2_DANRE B3DHF2_DANRE -----------------------------I Q4SY29_TETNG Q4SY29_TETNG -----------------------------N P87342_ORYLA P87342_ORYLA -----------------------------T Q9W614_ORYLA Q9W614_ORYLA -----------------------------T MATCH CONSENSUS ??????????????????????????????

GUC2D_RAT GUC2D_RAT NRSYLVLDDDGPLQEAYDAVLTISLDTSPE Q4TAT8_TETNG Q4TAT8_TETNG DTAFPQLTNSTQLRHAYSSVLTVTMAS--E P79999_ORYLA P79999_ORYLA DMTFHQLTNSTQLRHAYSAVLTVTMES--D Q7T2Q2_ORYLA Q7T2Q2_ORYLA DMTFHQLTNSTQLRHAYSAVLTVTMES--D A2BFQ0_DANRE A2BFQ0_DANRE NVKYPILANDSKLRRAYDGVLTVTMDQG-E Q4S8Y6_TETNG Q4S8Y6_TETNG NAQYYSLGNDTKLRKAYDGVLTITMDSG-E P87343_ORYLA P87343_ORYLA DAFYYMLGNDTKLRRAFDGVLTITMESG-E Q9W616_ORYLA Q9W616_ORYLA DAFYYMLGNDTKLRRAFDGVLTITMESG-E Q4T7P7_TETNG Q4T7P7_TETNG NVTYAALKSNGKLLRAYDAVLTVTIDSP-R Q7T3I2_ORYLA Q7T3I2_ORYLA NITYPALKSNSKLLRAYDAVLTVTIDSP-H Q9W615_ORYLA Q9W615_ORYLA NITYPALKSNSKLLRAYDAVLTVTIDSP-H O57480_CHICK O57480_CHICK RVPYPILANSTKLRLAYDAVLTITIDSP-E GUC2E_RAT GUC2E_RAT PEALAAFVNSSKLRRAHDAVLTLTRRCPPG Q8C8X5_MOUSE Q8C8X5_MOUSE PEALAAFVNSSQLRRAHDAVLTLTRRCPPG B1ASX7_MOUSE B1ASX7_MOUSE PEALAAFVNSSQLRRAHDAVLTLTRRCPPG GUC2E_MOUSE GUC2E_MOUSE PEALAAFVNSSQLRRAHDAVLTLTRRCPPG GUC2D_HUMAN GUC2D_HUMAN PEALAALANSSQLRRAHDAVLTLTRHCPSE GUC2D_BOVIN GUC2D_BOVIN PDALAVLANSSQLRKAHDAVLTLTRHCPLG GUC2D_CANFA GUC2D_CANFA PEALAVLANSSQLRRAHDAVLILTRHCPPG GUC2F_BOVIN GUC2F_BOVIN HTPYKVLRNNPKLREAYDAVLTITVESQ-E GUC2F_HUMAN GUC2F_HUMAN HTPYQVLRNNPKLREAYDAVLTITVESQ-E GUC2F_MOUSE GUC2F_MOUSE HSPYQVLRNNPKLREAYDAVLTITVESH-E GUC2F_RAT GUC2F_RAT HSPYQVLRNNQKLREAYDAVLTITVESH-E Q9PUK0_RANPI Q9PUK0_RANPI NNSYPIFDKNSTLHAAYDAVLTITMDYE-E B3DHF2_DANRE B3DHF2_DANRE NITYYPLQNNSKLSKAYDAVLTITLDSD-I Q4SY29_TETNG Q4SY29_TETNG NVSHKPLQSNSQLREAYDAVLTITVASE-P P87342_ORYLA P87342_ORYLA NVSHFALKNNSSLKEAYDAVLTITMASE-P Q9W614_ORYLA Q9W614_ORYLA NVSHFALKNNSSLKEAYDAVLTITMASE-P MATCH : .. * *...** :: CONSENSUS ??????L?????L??A?DAVLT?T??????

GUC2D_RAT GUC2D_RAT S---HAFTATKMRGGAAANLGPEQ------ Q4TAT8_TETNG Q4TAT8_TETNG QSFYEAFREMQINREIRSAVAVTQ------ P79999_ORYLA P79999_ORYLA QNFYQAFRQAQMSREIRSAISATE------ Q7T2Q2_ORYLA Q7T2Q2_ORYLA QNFYQAFRQAQMSREIRSAISATE------ A2BFQ0_DANRE A2BFQ0_DANRE QNFYEAFNAAQESFEIRGSTSAEE------ Q4S8Y6_TETNG Q4S8Y6_TETNG RNFYEAFKDAQDSYEIRSSTNPEQARPLNT P87343_ORYLA P87343_ORYLA RNFYEAFKDAQDRFELRSSTPTEQ------ Q9W616_ORYLA Q9W616_ORYLA RNFYEAFKDAQDRFELRSSTPAEQ------ Q4T7P7_TETNG Q4T7P7_TETNG MSFYESYREAMEKREVAATLKPQE------ Q7T3I2_ORYLA Q7T3I2_ORYLA TSFYETYREVMERGEVPTTLKPQQ------ Q9W615_ORYLA Q9W615_ORYLA TSFYETYREVMERGEVPTTLKPQQ------ O57480_CHICK O57480_CHICK VSFHEALRQAQEAYEIPAHIDPTQ------ GUC2E_RAT GUC2E_RAT GSVQDSLRRAQEHQELPLDLDLKQ------ Q8C8X5_MOUSE Q8C8X5_MOUSE GSVQDSLRRAQEHQELPLDLNLKQ------ B1ASX7_MOUSE B1ASX7_MOUSE GSVQDSLRRAQEHQELPLDLNLKQ------ GUC2E_MOUSE GUC2E_MOUSE GSVQDSLRRAQEHQELPLDLNLKQ------ GUC2D_HUMAN GUC2D_HUMAN GSVLDSLRRAQERRELPSDLNLQQ------ GUC2D_BOVIN GUC2D_BOVIN GSVRDSLRRAQEHRELPLDLNLQQ------ GUC2D_CANFA GUC2D_CANFA GSVMDNLRRAQEHQELPSDLDLQQ------ GUC2F_BOVIN GUC2F_BOVIN KTFYQAFEEAAARGEIPEKLESDQ------ GUC2F_HUMAN GUC2F_HUMAN KTFYQAFTEAAARGEIPEKLEFDQ------ GUC2F_MOUSE GUC2F_MOUSE KTFYEAYAEAAARGEIPEKPDSNQ------ GUC2F_RAT GUC2F_RAT KTFYEAFTEAAAGGEIPEKLDSHQ------ Q9PUK0_RANPI Q9PUK0_RANPI KSFYEVFAELKEKGEIKTNLEPQQ------ B3DHF2_DANRE B3DHF2_DANRE MTFNEAFNAAKQLGELMVTQEPEQ------ Q4SY29_TETNG Q4SY29_TETNG LSFNEAFAAAKENQEVTLDVRPEQ------ P87342_ORYLA P87342_ORYLA LSFNEAFEAARKSGEITLPVQPEQ------ Q9W614_ORYLA Q9W614_ORYLA LSFNEAFEAARKSGEITLPVQPEQ------ MATCH . : CONSENSUS ?????????A????E????????Q??????

GUC2D_RAT GUC2D_RAT -VSPLFGTIYDAVILLAHALNHSETH--GT Q4TAT8_TETNG Q4TAT8_TETNG -VSPLFGTIFNMVYFIAKSVEERRQAGGGR P79999_ORYLA P79999_ORYLA -VSPVFGTIFNMVYFVAKAVEERRLAGGGH Q7T2Q2_ORYLA Q7T2Q2_ORYLA -VSPVFGTIFNMVYFVAKAVEERRLAGGGH A2BFQ0_DANRE A2BFQ0_DANRE -VSPFFGTIYNMIYYTAMAAEQSRASSGGR Q4S8Y6_TETNG Q4S8Y6_TETNG EVSPFFGTIYNMMYYIAMAAEQARAN-GGH P87343_ORYLA P87343_ORYLA -VSPFFGTIYNMMYYIAMAVEQTRAS-GVH Q9W616_ORYLA Q9W616_ORYLA -VSPFFGTIYNMMYYIAMAVEQTRAS-GVH Q4T7P7_TETNG Q4T7P7_TETNG -VSPLFGTIYNSIFFMAHAVHHLRQS--GE Q7T3I2_ORYLA Q7T3I2_ORYLA -VSPMFGTIYNSVLLMAHAIKGVRDS--GA Q9W615_ORYLA Q9W615_ORYLA -VSPMFGTIYNSVLLMAHAIKGVRDS--GA O57480_CHICK O57480_CHICK -VHPLFATIYNSIYFLANAVEATRRS--GR GUC2E_RAT GUC2E_RAT -VSPLFGTIYDAVFLLAGGVTRARAAVGGG Q8C8X5_MOUSE Q8C8X5_MOUSE -VSPLFGTIYDAVFLLAGGVKRARTAVGGG B1ASX7_MOUSE B1ASX7_MOUSE -VSPLFGTIYDAVFLLAGGVKRARTAVGGG GUC2E_MOUSE GUC2E_MOUSE -VSPLFGTIYDAVFLLAGGVKRARTAVGGG GUC2D_HUMAN GUC2D_HUMAN -VSPLFGTIYDAVFLLARGVAEARAAAGGR GUC2D_BOVIN GUC2D_BOVIN -VSPLFGTIYDSVFLLAGGVARARVAAGGG GUC2D_CANFA GUC2D_CANFA -VSPFFGTIYDAVLLLAGGVARARAAAGGG GUC2F_BOVIN GUC2F_BOVIN -VSPLFGTIYNSIYFIAQAMNNAMKE--NG GUC2F_HUMAN GUC2F_HUMAN -VSPLFGTIYNSIYFIAQAMNNAMKE--NG GUC2F_MOUSE GUC2F_MOUSE -VSPLFGTIYNSIYFIAQAMNNAMKK--NG GUC2F_RAT GUC2F_RAT -VSPLFGTIYNSIYFIAQAMSNALKE--NG Q9PUK0_RANPI Q9PUK0_RANPI -VSPLFGTIYNSMYLLAKAMSSAWKQ--GA B3DHF2_DANRE B3DHF2_DANRE -VSPLFGTIYNSLYLLAKSMHNARRA--GR Q4SY29_TETNG Q4SY29_TETNG -VHPLFGTIYNSIYILARSIHNTRKG--GM P87342_ORYLA P87342_ORYLA -VNPLFGTIYNSIYLMARSIHNARKA--GM Q9W614_ORYLA Q9W614_ORYLA -VNPLFGTIYNSIYLMARSIHNARKA--GM MATCH * *.*.**:: : * . CONSENSUS ?VSP?FGTIY??????A?????????????

GUC2D_RAT GUC2D_RAT GLSGAHLGNHIRALDVAGFSQRIRIDGKGR Q4TAT8_TETNG Q4TAT8_TETNG WVTGNQLVHSDGGFEFQGFNQLLYGGSEGQ P79999_ORYLA P79999_ORYLA WVTGSQLFQSDGGFEFQGFNQVLYGGKGGR Q7T2Q2_ORYLA Q7T2Q2_ORYLA WVTGSQLFQSDGGFEFQGFNQVLYGGKGGR A2BFQ0_DANRE A2BFQ0_DANRE WVSGDLLSQNEGGFEFDGFNQRISGGTNGE Q4S8Y6_TETNG Q4S8Y6_TETNG WVTGHILGESKGGFEFEGFNQPLRAGRNSQ P87343_ORYLA P87343_ORYLA WVTGRSLGNSEGGFEFEGFNQPLQAGRNGE Q9W616_ORYLA Q9W616_ORYLA WVTGRSLGNSEGGFEFEGFNQPLQAGRNGE Q4T7P7_TETNG Q4T7P7_TETNG WMSGGNLARRTRNLAIQGFSHWLRTNASGS Q7T3I2_ORYLA Q7T3I2_ORYLA WISGGNLAHQTRNLNFQGFSHRIKTSSSGA Q9W615_ORYLA Q9W615_ORYLA WISGGNLAHQTRNLNFQGFSHRIKTSSSGA O57480_CHICK O57480_CHICK WVMGSSVAENARDFQMEGFCQPFSVTEDGD GUC2E_RAT GUC2E_RAT WVSGASVARQMREAQVFGFCGIL-----GR Q8C8X5_MOUSE Q8C8X5_MOUSE WVSGASVARQVREAQVSGFCGVL-----GR B1ASX7_MOUSE B1ASX7_MOUSE WVSGASVARQVREAQVSGFCGVL-----GR GUC2E_MOUSE GUC2E_MOUSE WVSGASVARQVREAQVSGFCGVL-----GR GUC2D_HUMAN GUC2D_HUMAN WVSGAAVARHIRDAQVPGFCGDL-----GG GUC2D_BOVIN GUC2D_BOVIN WVSGAAVARHIRDARVPGFCGAL-----GG GUC2D_CANFA GUC2D_CANFA WVSGATVAHHIPDAQVPGFCGTL-----GG GUC2F_BOVIN GUC2F_BOVIN WASAASLVQHSRNVQFYGFNQLIRTDANGN GUC2F_HUMAN GUC2F_HUMAN QAGAASLVQHSRNMQFHGFNQLMRTDSNGN GUC2F_MOUSE GUC2F_MOUSE RASAASLVQHSRNMQFYGFNQLIKTDSNGN GUC2F_RAT GUC2F_RAT QASAASLTRHSRNMQFYGFNQLIRTDSNGN Q9PUK0_RANPI Q9PUK0_RANPI WISGTNLVEYTKNLDYPGFTHMLYTDGKGN B3DHF2_DANRE B3DHF2_DANRE WLSGTNLAYFTRNITFTGFNQDIQTDEQGN Q4SY29_TETNG Q4SY29_TETNG SLSGSNLAYFTKNIDFTGFNQNVKVDSQGQ P87342_ORYLA P87342_ORYLA TLSGSNVAYYTKNTNFDGFNQRFEVDSRGQ Q9W614_ORYLA Q9W614_ORYLA TLSGSNVAYYTKNTNFDGFNQRFEVDSRGQ MATCH . : ** . . CONSENSUS ???G?????????????GF?????????G?

GUC2D_RAT GUC2D_RAT RL-PQYVILDTNGEGSQLVPTHILDVS--- Q4TAT8_TETNG Q4TAT8_TETNG GLQAKYVVLDSD--GDRLVPTHSLAPSHSA P79999_ORYLA P79999_ORYLA GLQARYVVLDSE--GDRLVPTHSLAPTHTD Q7T2Q2_ORYLA Q7T2Q2_ORYLA GLQARYVVLDSE--GDRLVPTHSLAPTHTD A2BFQ0_DANRE A2BFQ0_DANRE GMQVRYAVLDSDGSGSSLYRTHALEASHTY Q4S8Y6_TETNG Q4S8Y6_TETNG GMQARYVVLDYSGMGTSLYSTHTLEPSHTD P87343_ORYLA P87343_ORYLA GMQAGYVVLDYSGMGNSLYSTHLLHPTHTD Q9W616_ORYLA Q9W616_ORYLA GMQAGYVVLDYSGMGNSLYSTHFLHPTHTD Q4T7P7_TETNG Q4T7P7_TETNG AL-VDYLILDTDGLSWELKPVYRIDME--- Q7T3I2_ORYLA Q7T3I2_ORYLA VQ-LDYLILDTDGSSSELLPTYRIDME--- Q9W615_ORYLA Q9W615_ORYLA VQ-LDYLILDTDGSSSELLPTYRIDME--- O57480_CHICK O57480_CHICK VN-VPYVVLDTDGKGDRLWPVYGLEPG--- GUC2E_RAT GUC2E_RAT TEEPSFVLLDTDAAGERLFTTHLLDPV--- Q8C8X5_MOUSE Q8C8X5_MOUSE TEEPSFVLLDTDASGEQLFATHLLDPV--- B1ASX7_MOUSE B1ASX7_MOUSE TEEPSFVLLDTDASGEQLFATHLLDPV--- GUC2E_MOUSE GUC2E_MOUSE TEEPSFVLLDTDASGEQLFATHLLDPV--- GUC2D_HUMAN GUC2D_HUMAN DEEPPFVLLDTDAAGDRLFATYMLDPA--- GUC2D_BOVIN GUC2D_BOVIN AEEPSFVLLDTDATGDQLFATYVLDPT--- GUC2D_CANFA GUC2D_CANFA AQEPPFVLLDTDAAGDRLFATYMLDPT--- GUC2F_BOVIN GUC2F_BOVIN GI-SEYVILDTNWKEWELHSTYTVDME--- GUC2F_HUMAN GUC2F_HUMAN GI-SEYVILDTNLKEWELHSTYTVDME--- GUC2F_MOUSE GUC2F_MOUSE GI-SEYVILDTNGKEWELRGTYTVDME--- GUC2F_RAT GUC2F_RAT GI-SEYVILDTNGKEWELRGTYTVDME--- Q9PUK0_RANPI Q9PUK0_RANPI GL-SSFVVLDTDGKINQLFPTYSVEVG--- B3DHF2_DANRE B3DHF2_DANRE GQ-TNYVILDTEAWGTQLYRCFLVDMT--- Q4SY29_TETNG Q4SY29_TETNG IR-SSYVVLDTDSTGSHLYRTYTVDLV--- P87342_ORYLA P87342_ORYLA VK-TSYVVLDSDSKGAELYQAYVVDLR--- Q9W614_ORYLA Q9W614_ORYLA VK-TSYVVLDSDSKGAELYQAYVVDLR--- MATCH : :** . * . : CONSENSUS ??????V?LD???????L??T?????????

GUC2D_RAT GUC2D_RAT --TQQVQPLGTAVHFP-GGSPPAHDASCWF Q4TAT8_TETNG Q4TAT8_TETNG GELGGLRPLGRSFIFP--GGRPSKDSFCWF P79999_ORYLA P79999_ORYLA GTVGGLRPLGRSFFFP--GGKPSKSSFCWF Q7T2Q2_ORYLA Q7T2Q2_ORYLA GTVGGLRPLGRSFFFP--GGKPSKSSFCWF A2BFQ0_DANRE A2BFQ0_DANRE GKYGGLKYLGKSIHFA--GASPSSDANCWF Q4S8Y6_TETNG Q4S8Y6_TETNG GITGGLKYLGRSIHFA--GSTPYTDSSCWF P87343_ORYLA P87343_ORYLA TMTGGLRYLGRSVHFA--GSTPYTDSSCWF Q9W616_ORYLA Q9W616_ORYLA TMTGGLRYLGRSVHFA--GSTPYTDSSCWF Q4T7P7_TETNG Q4T7P7_TETNG --AGSVRFLGRDIHFP-RGFGPRRDSSCWF Q7T3I2_ORYLA Q7T3I2_ORYLA --IGMVRFLGRDIHFP-HGYGPRRDAACWF Q9W615_ORYLA Q9W615_ORYLA --IGMVRFLGRDIHFP-HGYGPRRDAACWF O57480_CHICK O57480_CHICK --IRGLAYRGHSVHWP-HSSSPGTDSGCWF GUC2E_RAT GUC2E_RAT --LGSLRSAGTPVHFPRGAPAPGPDPSCWF Q8C8X5_MOUSE Q8C8X5_MOUSE --LGSLRSAGTPMHFPRGGPAPGPDPSCWF B1ASX7_MOUSE B1ASX7_MOUSE --LGSLRSAGTPMHFPRGGPAPGPDPSCWF GUC2E_MOUSE GUC2E_MOUSE --LGSLRSAGTPMHFPRGGPAPGPDPSCWF GUC2D_HUMAN GUC2D_HUMAN --RGSFLSAGTRMHFPRGGSAPGPDPSCWF GUC2D_BOVIN GUC2D_BOVIN --QGFFHSAGTPVHFPKGGRGPGPDPSCWF GUC2D_CANFA GUC2D_CANFA --RGSLLSAGTPVHFPRGGGTPGSDPSCWF GUC2F_BOVIN GUC2F_BOVIN --TELLRFGETPIHFP-GGRPPRADAQCWF GUC2F_HUMAN GUC2F_HUMAN --MELLRFGGTPIHFP-GGRPPRADAKCWF GUC2F_MOUSE GUC2F_MOUSE --TELLRFRGTPIHFP-GGRPTSADAKCWF GUC2F_RAT GUC2F_RAT --TELLRFRGTPIHFP-GGRPTSADAKCWF Q9PUK0_RANPI Q9PUK0_RANPI --INLVRFLGKTIRFP-GGTPPTADSSCWF B3DHF2_DANRE B3DHF2_DANRE --SDLVLFAGRFIHFP-GESPPPSDSRCWF Q4SY29_TETNG Q4SY29_TETNG --SQRLRFAGRSINFP-GGSPPSSDSICWF P87342_ORYLA P87342_ORYLA --SGVLRFTGRSIHFP-GGSPPVADSSCWF Q9W614_ORYLA Q9W614_ORYLA --SGVLRFTGRSIHFP-GGSPPVADSSCWF MATCH . . :. . .. *** CONSENSUS ?????????G???HFP??G??P??D??CWF

GUC2D_RAT GUC2D_RAT DPNTLCIRG-----VQPLGSLLTLTITCVL Q4TAT8_TETNG Q4TAT8_TETNG SPDEACTGG-----MDATTMFSVFVLVCLL P79999_ORYLA P79999_ORYLA SPEEACSGG-----LDAVSLFFILLLLCAV Q7T2Q2_ORYLA Q7T2Q2_ORYLA SPEEACSGG-----LDAVSLFFILLLLCAV A2BFQ0_DANRE A2BFQ0_DANRE SPYIACSGGNKNNRLDGVTLFFLLMFFIVL Q4S8Y6_TETNG Q4S8Y6_TETNG SPYFACSGG-----MDSVTLLFLLLLLIAL P87343_ORYLA P87343_ORYLA SPYFACSGG-----WDSTTAFFVFVLLILF Q9W616_ORYLA Q9W616_ORYLA SPYFACSGG-----WDSTTAFFVFVLLILF Q4T7P7_TETNG Q4T7P7_TETNG TPGVICSGG-----VDLFLTVAIFCGAITA Q7T3I2_ORYLA Q7T3I2_ORYLA IPGVICSGG-----VDLFLTFSTFLGSIAV Q9W615_ORYLA Q9W615_ORYLA IPGVICSGG-----VDLFLTFSTFLGSIAV O57480_CHICK O57480_CHICK ESGSICNGG-----MDASFVLLIFILVSAL GUC2E_RAT GUC2E_RAT DPDVICNGG-----VEPGLVFVGFLLVIVV Q8C8X5_MOUSE Q8C8X5_MOUSE DPDVICNGG-----VEPGLVFVGFLLVIGM B1ASX7_MOUSE B1ASX7_MOUSE DPDVICNGG-----VEPGLVFVGFLLVIGM GUC2E_MOUSE GUC2E_MOUSE DPDVICNGG-----VEPGLVFVGFLLVIGM GUC2D_HUMAN GUC2D_HUMAN DPNNICGGG-----LEPGLVFLGFLLVVGM GUC2D_BOVIN GUC2D_BOVIN DPDTICNGG-----VEPSVVFIGFLLVVGM GUC2D_CANFA GUC2D_CANFA EPGVICNGG-----VEPGLVFLGFLLVVGM GUC2F_BOVIN GUC2F_BOVIN ADGRICQGG-----INPTFALMVCLALLIA GUC2F_HUMAN GUC2F_HUMAN AEGKICHGG-----IDPAFAMMVCLTLLIA GUC2F_MOUSE GUC2F_MOUSE AERKICQGG-----IDPALAMMVCFALLIA GUC2F_RAT GUC2F_RAT AQGKICQGG-----IDPALAMMVCFALLLA Q9PUK0_RANPI Q9PUK0_RANPI DPDTLCIGG-----IEPSIVILVFGLVFAL B3DHF2_DANRE B3DHF2_DANRE EDNAICTGG-----VDIIYVIIAFVIVLII Q4SY29_TETNG Q4SY29_TETNG DKNIICTGG-----VEITYIVVIFAVLFAL P87342_ORYLA P87342_ORYLA EENAVCTGG-----VEVTYIIIVLAVILSM Q9W614_ORYLA Q9W614_ORYLA EENAVCTGG-----VEVTYIIIVLAVILSM MATCH * * : . CONSENSUS ?????C?GG?????????????????????

GUC2D_RAT GUC2D_RAT ALVGGFLAYFIRL--GLQQLRLLRG----P Q4TAT8_TETNG Q4TAT8_TETNG VAASLYWFRKYRR--AQSI----------- P79999_ORYLA P79999_ORYLA IAASFFWIRKYKK--SANL----------- Q7T2Q2_ORYLA Q7T2Q2_ORYLA IAASFFWIRKYKK--SANL----------- A2BFQ0_DANRE A2BFQ0_DANRE IAGAGILFLQVRKYGAGGFFGAFIGGGGSP Q4S8Y6_TETNG Q4S8Y6_TETNG AGVGANFFFAFKRHGRVGFSFGGGGGG--A P87343_ORYLA P87343_ORYLA AGFGANIILRFKREGRVGFSFGGDGNGG-P Q9W616_ORYLA Q9W616_ORYLA AGFGANIILRFKREGRVGFSFGGDGNGG-P Q4T7P7_TETNG Q4T7P7_TETNG IVFTVALIYCVRR--RINQIRMVRG----P Q7T3I2_ORYLA Q7T3I2_ORYLA ALFLIALLYCIRR--RINQIRLVRG----P Q9W615_ORYLA Q9W615_ORYLA ALFLIALLYCIRR--RINQIRLVRG----P O57480_CHICK O57480_CHICK VAAGAALACFIRR--RIQQAQLMKG----P GUC2E_RAT GUC2E_RAT GLTGAFLAHYLRH--RLLHMQMVSG----P Q8C8X5_MOUSE Q8C8X5_MOUSE GLTGAFLAHYLRH--RLLHMQMASG----P B1ASX7_MOUSE B1ASX7_MOUSE GLTGAFLAHYLRH--RLLHMQMASG----P GUC2E_MOUSE GUC2E_MOUSE GLTGAFLAHYLRH--RLLHMQMASG----P GUC2D_HUMAN GUC2D_HUMAN GLAGAFLAHYVRH--RLLHMQMVSG----P GUC2D_BOVIN GUC2D_BOVIN GLAGAFLAHYCRH--RLLHIQMVSG----P GUC2D_CANFA GUC2D_CANFA GLTGAFLAHYLRH--RLLHIQMVSG----P GUC2F_BOVIN GUC2F_BOVIN LLSINGFAYFIRH--RINKIQLIKG----P GUC2F_HUMAN GUC2F_HUMAN LLSINGFAYFIRR--RINKIQLIKG----P GUC2F_MOUSE GUC2F_MOUSE LLSINGFAYFIRR--RINKIQLIKG----P GUC2F_RAT GUC2F_RAT LLSINGFAYFIRR--RINKIQLIKG----P Q9PUK0_RANPI Q9PUK0_RANPI ALCGVGVSYLIRH--SLLQIQLVKG----P B3DHF2_DANRE B3DHF2_DANRE VLGSIGLSLFIRR--RIQQIQLIKG----P Q4SY29_TETNG Q4SY29_TETNG AIGGLIISLFIRR--RLQQIQLVKG----P P87342_ORYLA P87342_ORYLA TVGGFFIGPYTRR--RLQQIQLVKG----P Q9W614_ORYLA Q9W614_ORYLA TVGGFFIGLYIRR--RLQQIQLVKG----P MATCH : CONSENSUS ???????????R????????????G????P

GUC2D_RAT GUC2D_RAT HRILLTPQELTFLQRTPSRRR-----PH-- Q4TAT8_TETNG Q4TAT8_TETNG AKIVLTLDNIVFIDTQVSRKVSAGGPAATT P79999_ORYLA P79999_ORYLA AKLILTLDDIVFIDTQVSRKK--------- Q7T2Q2_ORYLA Q7T2Q2_ORYLA AKLILTLDDIVFIDTQVSRKK--------- A2BFQ0_DANRE A2BFQ0_DANRE TKIVLTLDDLVFINTTLSRRK--------- Q4S8Y6_TETNG Q4S8Y6_TETNG AKVVLTLDDLIFINTQISKRVSPK------ P87343_ORYLA P87343_ORYLA SKVVLTLDDLVLINTQVSKRK--------- Q9W616_ORYLA Q9W616_ORYLA SKVVLTLDDLVFINTQVSKRK--------- Q4T7P7_TETNG Q4T7P7_TETNG NKILLTLDDVTFINPSLSNKVSPFFNLD-- Q7T3I2_ORYLA Q7T3I2_ORYLA NKILLTLTDVTFINPSLSNKK---LSLD-- Q9W615_ORYLA Q9W615_ORYLA NKILLTLTDVTFINPSLSNKK---LSLD-- O57480_CHICK O57480_CHICK NKIILTMEDLTFINTQSNKRV--------- GUC2E_RAT GUC2E_RAT NKIILTLEDVTFLHPQGGSSR--------- Q8C8X5_MOUSE Q8C8X5_MOUSE NKIILTLEDVTFLHPPGGSSR--------- B1ASX7_MOUSE B1ASX7_MOUSE NKIILTLEDVTFLHPPGGSSR--------- GUC2E_MOUSE GUC2E_MOUSE NKIILTLEDVTFLHPPGGSSR--------- GUC2D_HUMAN GUC2D_HUMAN NKIILTVDDITFLHPHGGTSR--------- GUC2D_BOVIN GUC2D_BOVIN NKIILTLDDITFLHPHGGNSR--------- GUC2D_CANFA GUC2D_CANFA NKIILTLDDVTFLHPHGGSTR--------- GUC2F_BOVIN GUC2F_BOVIN NRILLTLEDVTFINPHFGSKRGSHASVS-- GUC2F_HUMAN GUC2F_HUMAN NRILLTLEDVTFINPHFGSKRGSRASVS-- GUC2F_MOUSE GUC2F_MOUSE NRILLTLEDVTFINPHFGSKRGSRASVS-- GUC2F_RAT GUC2F_RAT NRILLTLEDVTFINPHFGSKRGSRASVS-- Q9PUK0_RANPI Q9PUK0_RANPI NKILLSLDDLTFINPKLSMKK-----IN-- B3DHF2_DANRE B3DHF2_DANRE NRILLTLEDLTFINPQLSKRK-----IT-- Q4SY29_TETNG Q4SY29_TETNG NRILLTLEDLTFINPQLSKKK-----IT-- P87342_ORYLA P87342_ORYLA NRILLTLEDLTFINPQLSKKE-----IT-- Q9W614_ORYLA Q9W614_ORYLA NRILLTLEDLTFINPQLSKKK-----IT-- MATCH :::*: :: ::. . CONSENSUS ??I?LTL?D??F??????????????????

GUC2D_RAT GUC2D_RAT ---------------------VDSGSESRS Q4TAT8_TETNG Q4TAT8_TETNG LAPGQMLAAVGHVLPLFSLKKLNDESIMRS P79999_ORYLA P79999_ORYLA ---------------------LNDESIMRS Q7T2Q2_ORYLA Q7T2Q2_ORYLA ---------------------LNDESIMRS A2BFQ0_DANRE A2BFQ0_DANRE ---------------------LNDESMLKS Q4S8Y6_TETNG Q4S8Y6_TETNG ---------------------SDFFFFFLS P87343_ORYLA P87343_ORYLA ---------------------LNDESIVKS Q9W616_ORYLA Q9W616_ORYLA ---------------------LNDESIVKS Q4T7P7_TETNG Q4T7P7_TETNG ---------------------DSRASGMRS Q7T3I2_ORYLA Q7T3I2_ORYLA ---------------------DSRTSGGRS Q9W615_ORYLA Q9W615_ORYLA ---------------------DSRTSGGRS O57480_CHICK O57480_CHICK -------------------------DGSRT GUC2E_RAT GUC2E_RAT ----------------------KVAQGSRS Q8C8X5_MOUSE Q8C8X5_MOUSE ----------------------KVVQGSRS B1ASX7_MOUSE B1ASX7_MOUSE ----------------------KVVQGSRS GUC2E_MOUSE GUC2E_MOUSE ----------------------KVVQGSRS GUC2D_HUMAN GUC2D_HUMAN ----------------------KVAQGSRS GUC2D_BOVIN GUC2D_BOVIN ----------------------KVAQGSRT GUC2D_CANFA GUC2D_CANFA ----------------------KVVQGSRS GUC2F_BOVIN GUC2F_BOVIN ---------------------FQITSEVQS GUC2F_HUMAN GUC2F_HUMAN ---------------------FQITSEVQS GUC2F_MOUSE GUC2F_MOUSE ---------------------FQIISEVQS GUC2F_RAT GUC2F_RAT ---------------------FQIISEVQS Q9PUK0_RANPI Q9PUK0_RANPI ---------------------IDNISDTKS B3DHF2_DANRE B3DHF2_DANRE ---------------------LEDLSDSKS Q4SY29_TETNG Q4SY29_TETNG ---------------------LEDLSESKS P87342_ORYLA P87342_ORYLA ---------------------LDDLSESKS Q9W614_ORYLA Q9W614_ORYLA ---------------------LDDLSESKS MATCH : CONSENSUS ?????????????????????????????S

GUC2D_RAT GUC2D_RAT VVDGG---SPQSVIQGSTRSVPAFLEHTNV Q4TAT8_TETNG Q4TAT8_TETNG LLEIK----TPVRSAARS-YILTSPDSSNV P79999_ORYLA P79999_ORYLA LLEIK----TPLRSIARS-YILTTPESSNI Q7T2Q2_ORYLA Q7T2Q2_ORYLA LLEIK----TPLRSIARS-YILTTPESSNI A2BFQ0_DANRE A2BFQ0_DANRE QLDVK---TPRHSVSGRS-YITSTPETSNV Q4S8Y6_TETNG Q4S8Y6_TETNG QLDIK---TPHHSVSGRS-YLASSPDSSNV P87343_ORYLA P87343_ORYLA QMDLK---TPHHSVSGRS-YLASTPDSSNI Q9W616_ORYLA Q9W616_ORYLA QMDLK---TPHHSVSGRS-YLASTPDSSNI Q4T7P7_TETNG Q4T7P7_TETNG ISERS----VVSPVSTKS-P--ATHENSNV Q7T3I2_ORYLA Q7T3I2_ORYLA LSECS----QNTPLSSQS-P--ATYENSNI Q9W615_ORYLA Q9W615_ORYLA LSECS----QNTPLSSQS-P--ATYENSNI O57480_CHICK O57480_CHICK SLAGR----STGDTKSIR-SVTAAPDTTNV GUC2E_RAT GUC2E_RAT SLATR----STSDIRSVP-S--QPQESTNI Q8C8X5_MOUSE Q8C8X5_MOUSE SLATR----SASDIRSVP-S--QPQESTNV B1ASX7_MOUSE B1ASX7_MOUSE SLATR----SASDIRSVP-S--QPQESTNV GUC2E_MOUSE GUC2E_MOUSE SLATR----SASDIRSVP-S--QPQESTNV GUC2D_HUMAN GUC2D_HUMAN SLGAR----SMSDIRSGP-S--QHLDSPNI GUC2D_BOVIN GUC2D_BOVIN SLAAR----SISDVRSIH-S--QLPDYTNI GUC2D_CANFA GUC2D_CANFA SLAAR----STSDIRSVP-S--QPLDNSNI GUC2F_BOVIN GUC2F_BOVIN GRSPR----LSFSSGSLT-P--ATCENSNI GUC2F_HUMAN GUC2F_HUMAN GRSPR----LSFSSGSLT-P--ATYENSNI GUC2F_MOUSE GUC2F_MOUSE GRSPR----LSFSSGSLT-P--ATYENSNI GUC2F_RAT GUC2F_RAT GRSPR----LSFSSGSLT-P--ATYENSNI Q9PUK0_RANPI Q9PUK0_RANPI VSDCRSLKSIARSLSTKS-A--VNHENSNV B3DHF2_DANRE B3DHF2_DANRE YIEEKSTGDRSRSVNSMA-T--ATHETSNV Q4SY29_TETNG Q4SY29_TETNG GLEEKSA-DHSHSVNSIQ-T--ASHETTNV P87342_ORYLA P87342_ORYLA ALDDKSA-DPSHSMNSMQ-T--AIHENSSV Q9W614_ORYLA Q9W614_ORYLA ALDDKSA-DPSHSMNSMQ-T--ATHENSSV MATCH : ..: CONSENSUS ????????????????????????????N?

GUC2D_RAT GUC2D_RAT ALYQ-------------------------- Q4TAT8_TETNG Q4TAT8_TETNG GILE-------------------------- P79999_ORYLA P79999_ORYLA GILE-------------------------- Q7T2Q2_ORYLA Q7T2Q2_ORYLA GILE-------------------------- A2BFQ0_DANRE A2BFQ0_DANRE AVFEVWEICEFLCTGIVFGSMMKQYYMRKC Q4S8Y6_TETNG Q4S8Y6_TETNG AVFE-------------------------- P87343_ORYLA P87343_ORYLA AVYE-------------------------- Q9W616_ORYLA Q9W616_ORYLA AVYE-------------------------- Q4T7P7_TETNG Q4T7P7_TETNG VIYE-------------------------- Q7T3I2_ORYLA Q7T3I2_ORYLA VIYE-------------------------- Q9W615_ORYLA Q9W615_ORYLA VIYE-------------------------- O57480_CHICK O57480_CHICK AIAEGNETPPGANSHLPL-----LLLLFNQ GUC2E_RAT GUC2E_RAT GLYE-------------------------- Q8C8X5_MOUSE Q8C8X5_MOUSE GLYE-------------------------- B1ASX7_MOUSE B1ASX7_MOUSE GLYE-------------------------- GUC2E_MOUSE GUC2E_MOUSE GLYE-------------------------- GUC2D_HUMAN GUC2D_HUMAN GVYE-------------------------- GUC2D_BOVIN GUC2D_BOVIN GLYE-------------------------- GUC2D_CANFA GUC2D_CANFA GLFE-------------------------- GUC2F_BOVIN GUC2F_BOVIN AIYE-------------------------- GUC2F_HUMAN GUC2F_HUMAN AIYE-------------------------- GUC2F_MOUSE GUC2F_MOUSE AIYE-------------------------- GUC2F_RAT GUC2F_RAT AIYQ-------------------------- Q9PUK0_RANPI Q9PUK0_RANPI AVYE-------------------------- B3DHF2_DANRE B3DHF2_DANRE AVYE-------------------------- Q4SY29_TETNG Q4SY29_TETNG AVYE-------------------------- P87342_ORYLA P87342_ORYLA AVYE-------------------------- Q9W614_ORYLA Q9W614_ORYLA AVYE-------------------------- MATCH : : CONSENSUS ???E??????????????????????????

GUC2D_RAT GUC2D_RAT --------GEWVWLKKFEAGTA---PDLRP Q4TAT8_TETNG Q4TAT8_TETNG --------GDWVWLKKIPVGRT--LPAVNH P79999_ORYLA P79999_ORYLA --------GDWVWLKKIPIGKT--TTAVNQ Q7T2Q2_ORYLA Q7T2Q2_ORYLA --------GDWVWLKKIPIGKT--TTAVNQ A2BFQ0_DANRE A2BFQ0_DANRE DFLTGYQKGDWVWLKKCPCADS--ITEISE Q4S8Y6_TETNG Q4S8Y6_TETNG --------GDWVWLKKCPSGVV---SSVNS P87343_ORYLA P87343_ORYLA --------GDLVWLKKCPTGSV---SSVSS Q9W616_ORYLA Q9W616_ORYLA --------GDWVWLKKCPTGSV---SSVSS Q4T7P7_TETNG Q4T7P7_TETNG --------GDWAWLKRLLDGRF---SNISP Q7T3I2_ORYLA Q7T3I2_ORYLA --------GDWAWLKRLPNGNF---GSINP Q9W615_ORYLA Q9W615_ORYLA --------GDWAWLKRLPNGNF---GSINP O57480_CHICK O57480_CHICK QGLVASVQGDWVWLKKFPGDQH---SEVKP GUC2E_RAT GUC2E_RAT --------GDWVWLKKFPGEHH---MAIRP Q8C8X5_MOUSE Q8C8X5_MOUSE --------GDWVWLKKFPGEHH---MAIRP B1ASX7_MOUSE B1ASX7_MOUSE --------GDWVWLKKFPGEHH---MAIRP GUC2E_MOUSE GUC2E_MOUSE --------GDWVWLKKFPGEHH---MAIRP GUC2D_HUMAN GUC2D_HUMAN --------GDRVWLKKFPGDQH---IAIRP GUC2D_BOVIN GUC2D_BOVIN --------GDWVWLKKFPGDRH---IAIRP GUC2D_CANFA GUC2D_CANFA --------GDWVWLKKFPGDQH---IAIRP GUC2F_BOVIN GUC2F_BOVIN --------GDWVWLKKFPSGNFGDIKSVES GUC2F_HUMAN GUC2F_HUMAN --------GDWVWLKKFSLGDFGDLKSIKS GUC2F_MOUSE GUC2F_MOUSE --------GDWVWLKKFPPGDFGDIKSIKS GUC2F_RAT GUC2F_RAT --------GDWVWLKKFPPGDFGDIKSIKS Q9PUK0_RANPI Q9PUK0_RANPI --------GDWVWLKKFEPGPY---HELRQ B3DHF2_DANRE B3DHF2_DANRE --------GDWVWLKKFTEGHF---KEVKQ Q4SY29_TETNG Q4SY29_TETNG --------GDWVWLKKFQEGHF---KEVKQ P87342_ORYLA P87342_ORYLA --------GDWVWLKKFEEGQF---KEVKQ Q9W614_ORYLA Q9W614_ORYLA --------GDWVWLKKFEEGQF---KEVKQ MATCH *: .***: : CONSENSUS ????????GDWVWLKK??????????????

GUC2D_RAT GUC2D_RAT SSLSLLRKMREMRHENVTAFLGLFVGP--- Q4TAT8_TETNG Q4TAT8_TETNG NTKNLFSQLREMRHENLNLYLGLFLDS--- P79999_ORYLA P79999_ORYLA NTQNLFSQLREMRHENLNLYLGLFVDS--- Q7T2Q2_ORYLA Q7T2Q2_ORYLA NTQNLFSQLREMRHENLNLYLGLFVDS--- A2BFQ0_DANRE A2BFQ0_DANRE STQTIFVKLRDMRHENLNLFLGLFMDT--- Q4S8Y6_TETNG Q4S8Y6_TETNG STENVFVMLRDMRHENINLFLGLFFDF--- P87343_ORYLA P87343_ORYLA STEMLFVKLRDMRHENLNLYLGLFFDS--- Q9W616_ORYLA Q9W616_ORYLA STEMLFVKLRDMRHENLNLYLGLFFDS--- Q4T7P7_TETNG Q4T7P7_TETNG KTSNVFELMKDMRHENVNPFLGFFHDC--- Q7T3I2_ORYLA Q7T3I2_ORYLA KTSDVFELMKDMRHENINPFLGFFHDC--- Q9W615_ORYLA Q9W615_ORYLA KTSDVFELMKDMRHENINPFLGFFHDC--- O57480_CHICK O57480_CHICK ATKLAFCKLRDLRHENVNLFLGFFHDC--- GUC2E_RAT GUC2E_RAT ATKMAFSKLRELRHENVALYLGLFLAGTAD Q8C8X5_MOUSE Q8C8X5_MOUSE ATKTAFSKLRELRHENVALYLGLFLAGTAD B1ASX7_MOUSE B1ASX7_MOUSE ATKTAFSKLRELRHENVALYLGLFLAGTAD GUC2E_MOUSE GUC2E_MOUSE ATKTAFSKLRELRHENVALYLGLFLAGTAD GUC2D_HUMAN GUC2D_HUMAN ATKTAFSKLQELRHENVALYLGLFLARGAE GUC2D_BOVIN GUC2D_BOVIN ATKMAFSKIRELRHENVALYLGLFLAGGAG GUC2D_CANFA GUC2D_CANFA ATKTAFSKLRELRHENVVLYLGLFLGSGGA GUC2F_BOVIN GUC2F_BOVIN SASDIFEMMKDLRHENINPLVGFFYDS--- GUC2F_HUMAN GUC2F_HUMAN RASDVFEMMKDLRHENINPLLGFFYDS--- GUC2F_MOUSE GUC2F_MOUSE SASDVFEMMKDLRHENVNPLLGFFYDS--- GUC2F_RAT GUC2F_RAT SASDVFEMMKDLRHENVNPLLGFFYDS--- Q9PUK0_RANPI Q9PUK0_RANPI STTSTLRKMKDLRNENVNPFLGFFSDC--- B3DHF2_DANRE B3DHF2_DANRE STTKIFTKMKDLRNENVNPFLGFFTDC--- Q4SY29_TETNG Q4SY29_TETNG STTKILTKMKDLRNENVNPFLGFFSDC--- P87342_ORYLA P87342_ORYLA STTKIFTKMKDLRNENVNPFLGFFLDC--- Q9W614_ORYLA Q9W614_ORYLA STTKIFTKMKDLRNENVNPFLGFFLDC--- MATCH : : ::::*:**: :*:* CONSENSUS ?T???F??????RHEN????LG?F??????

GUC2D_RAT GUC2D_RAT -------EVSA-MVLEHCARGSLEDLLRNE Q4TAT8_TETNG Q4TAT8_TETNG -------GIFA-LVEEHCPRGSLADLLSDP P79999_ORYLA P79999_ORYLA -------GILALVVPEHCPRGSLADLLADS Q7T2Q2_ORYLA Q7T2Q2_ORYLA -------GILA-LVVEHCPRGSLADLLADS A2BFQ0_DANRE A2BFQ0_DANRE -------GIFG-IVTEHCTRGSLEDLLNNE Q4S8Y6_TETNG Q4S8Y6_TETNG -------GIFG-VVTEHCSRGSLEDLLNNE P87343_ORYLA P87343_ORYLA -------GIFG-IVTEHCIRGSLEDLLANE Q9W616_ORYLA Q9W616_ORYLA -------GIFG-IVTEHCIRGSLEDLLANE Q4T7P7_TETNG Q4T7P7_TETNG -------GLFA-IVTEFCSRGSLEDLLQND Q7T3I2_ORYLA Q7T3I2_ORYLA -------GVFA-IVTEFCSRGSLEDLLLND Q9W615_ORYLA Q9W615_ORYLA -------GVFA-IVTEFCSRGSLEDLLLND O57480_CHICK O57480_CHICK -------GIFA-IVSEHCSRGSLEDLLRNQ GUC2E_RAT GUC2E_RAT SPATPGEGILA-VVSEHCARGSLHDLLAQR Q8C8X5_MOUSE Q8C8X5_MOUSE SPATPGEGILA-VVSEHCARGSLHDLLAQR B1ASX7_MOUSE B1ASX7_MOUSE SPATPGEGILA-VVSEHCARGSLHDLLAQR GUC2E_MOUSE GUC2E_MOUSE SPATPGEGILA-VVSEHCARGSLHDLLAQR GUC2D_HUMAN GUC2D_HUMAN GPAALWEGNLA-VVSEHCTRGSLQDLLAQR GUC2D_BOVIN GUC2D_BOVIN GPAAPGEGVLA-VVSEHCARGSLQDLLAQR GUC2D_CANFA GUC2D_CANFA GGSAAGEGVLA-VVSEHCARGSLHDLLAQR GUC2F_BOVIN GUC2F_BOVIN -------GVFA-IVTEFCSRRSLEDILMNQ GUC2F_HUMAN GUC2F_HUMAN -------GMFA-IVTEFCSRGSLEDILTNQ GUC2F_MOUSE GUC2F_MOUSE -------GMFA-IVSEFCSRRSLEDILTND GUC2F_RAT GUC2F_RAT -------GMFA-IVSEFCSRRSLEDILTQD Q9PUK0_RANPI Q9PUK0_RANPI -------GIFA-IVTEHCSRGSLEDLLRND B3DHF2_DANRE B3DHF2_DANRE -------EMFA-IVTEHCSRGSLHDLLRND Q4SY29_TETNG Q4SY29_TETNG -------SMFA-VVTEHCSRGSLQDLLRNE P87342_ORYLA P87342_ORYLA -------SMFA-VVTEHCSRGSLQDLLRNE Q9W614_ORYLA Q9W614_ORYLA -------SMFA-VVTEHCSRGSLQDLLRNE MATCH . :* *.* * ** *:* : CONSENSUS ???????G??A??V?E?C?RGSL?DLL???

GUC2D_RAT GUC2D_RAT DLRLDWTFKASLLLDLIR------------ Q4TAT8_TETNG Q4TAT8_TETNG NMRLDWMFKSSLLMDLIKVSGGHRGVGVQQ P79999_ORYLA P79999_ORYLA DVRLDWMFKSSLLMDLIK------------ Q7T2Q2_ORYLA Q7T2Q2_ORYLA DVRLDWMFKSSLLMDLIK------------ A2BFQ0_DANRE A2BFQ0_DANRE EMRLDWMFKSSLLLDLIR------------ Q4S8Y6_TETNG Q4S8Y6_TETNG NVRLDWMFKSSLLMDLIR------------ P87343_ORYLA P87343_ORYLA DVRLDWMFKSSLLMDLIR------------ Q9W616_ORYLA Q9W616_ORYLA DVRLDWMFKSSLLMDLIR------------ Q4T7P7_TETNG Q4T7P7_TETNG DVKLDWMFKSSLLLDLIK------------ Q7T3I2_ORYLA Q7T3I2_ORYLA DVKLDWMFKSSLLLDLIK------------ Q9W615_ORYLA Q9W615_ORYLA DVKLDWMFKSSLLLDLIK------------ O57480_CHICK O57480_CHICK DMKLDWMFKSSLLIDLIK------------ GUC2E_RAT GUC2E_RAT DIKLDWMFKSSLLLDLIK------------ Q8C8X5_MOUSE Q8C8X5_MOUSE EIKLDWMFKSSLLLDLIK------------ B1ASX7_MOUSE B1ASX7_MOUSE EIKLDWMFKSSLLLDLIK------------ GUC2E_MOUSE GUC2E_MOUSE EIKLDWMFKSSLLLDLIK------------ GUC2D_HUMAN GUC2D_HUMAN EIKLDWMFKSSLLLDLIK------------ GUC2D_BOVIN GUC2D_BOVIN DIKLDWMFKSSLLLDLIK------------ GUC2D_CANFA GUC2D_CANFA DIKLDWMFKSSLLLDLIK------------ GUC2F_BOVIN GUC2F_BOVIN DVKLDWMFKSSLLLDLIK------------ GUC2F_HUMAN GUC2F_HUMAN DVKLDWMFKSSLLLDLIK------------ GUC2F_MOUSE GUC2F_MOUSE DVKLDWMFKSSLLLDLIK------------ GUC2F_RAT GUC2F_RAT DVKLDWMFKSSLLLDLIK------------ Q9PUK0_RANPI Q9PUK0_RANPI DVKLDWMFKSSLLLDLIK------------ B3DHF2_DANRE B3DHF2_DANRE DVKLDWMFKSSLVLDLIK------------ Q4SY29_TETNG Q4SY29_TETNG DVKLDWMFKSSLLLDLIK------------ P87342_ORYLA P87342_ORYLA DVKLDWMFKSSLLLDLIK------------ Q9W614_ORYLA Q9W614_ORYLA DVKLDWMFKSSLLLDLIK------------ MATCH :::*** **:**::***: CONSENSUS ???LDWMFKSSLL?DLIK????????????

GUC2D_RAT GUC2D_RAT --------GLRYLHHRHFPHGRLKSRN-CV Q4TAT8_TETNG Q4TAT8_TETNG CLTPSGFQGMKYLHLRGLCHGRLKSTN-CL P79999_ORYLA P79999_ORYLA --------GMKYLHLRGLTHGRLKSTN-CL Q7T2Q2_ORYLA Q7T2Q2_ORYLA --------GMKYLHLRGLTHGRLKSTN-CL A2BFQ0_DANRE A2BFQ0_DANRE --------GMKYLHNRGIIHGRLKSRN-CV Q4S8Y6_TETNG Q4S8Y6_TETNG --------GMKYLHNRDIIHGRLKSRN-CV P87343_ORYLA P87343_ORYLA --------GMKYLRHRNIIHGRLKSRN-CV Q9W616_ORYLA Q9W616_ORYLA --------GMKYLHHRNIIHGRLKSRN-CV Q4T7P7_TETNG Q4T7P7_TETNG --------GMKYLHHRGVSHSRLKSRN-CV Q7T3I2_ORYLA Q7T3I2_ORYLA --------GMKYLHHRGVCHTRLKSRN-CV Q9W615_ORYLA Q9W615_ORYLA --------GMKYLHHRGVCHTRLKSRN-CV O57480_CHICK O57480_CHICK --------GMRYLHHRDVVHGRRKSRN-CV GUC2E_RAT GUC2E_RAT --------GMRYLHHRGVAHGRLKSRN-CV Q8C8X5_MOUSE Q8C8X5_MOUSE --------GMRYLHHRGVAHGRLKSRN-CV B1ASX7_MOUSE B1ASX7_MOUSE --------GMRYLHHRGVAHGRLKSRN-CV GUC2E_MOUSE GUC2E_MOUSE --------GMRYLHHRGVAHGRLKSRN-CV GUC2D_HUMAN GUC2D_HUMAN --------GIRYLHHRGVAHGRLKSRN-CI GUC2D_BOVIN GUC2D_BOVIN --------GIRYLHHRGVAHGRLKSRN-CV GUC2D_CANFA GUC2D_CANFA --------GMRYLHHRGVAHGRLKSRN-CV GUC2F_BOVIN GUC2F_BOVIN --------GMKYLHHREFAHGRLKSRN-CV GUC2F_HUMAN GUC2F_HUMAN --------GMKYLHHREFVHGRLKSRN-CV GUC2F_MOUSE GUC2F_MOUSE --------GMKYLHHREFIHGRLKSRN-CV GUC2F_RAT GUC2F_RAT --------GMKYLHHREFIHGRLKSRN-CV Q9PUK0_RANPI Q9PUK0_RANPI --------GMRYLHHRDFQHGRLKSRNDCV B3DHF2_DANRE B3DHF2_DANRE --------GMKYLHHREFPHGRLKSRN-CV Q4SY29_TETNG Q4SY29_TETNG --------GMKYLHHRDFAHGRLKSRN-CV P87342_ORYLA P87342_ORYLA --------GMKYLHHREFPHGRLKSRN-CV Q9W614_ORYLA Q9W614_ORYLA --------GMKYLHHREFPHGRLKSRN-CV MATCH *::**: * . * * ** * *: CONSENSUS ????????GM?YLHHR???HGRLKSRN?CV

GUC2D_RAT GUC2D_RAT VDTRFVLKITDHGYAEFLESHCSFRPQPAP Q4TAT8_TETNG Q4TAT8_TETNG VDGRFVLKVTDYGLPMILHSQNLQVPEDEQ P79999_ORYLA P79999_ORYLA VDGRFVLKITDYGLPMILQSQNLSLPEDP- Q7T2Q2_ORYLA Q7T2Q2_ORYLA VDGRFVLKITDYGLPMILQSQNLSLPEDP- A2BFQ0_DANRE A2BFQ0_DANRE VDGRFVLKVTDYGFNEILNCQNIILEDNAP Q4S8Y6_TETNG Q4S8Y6_TETNG VDGRFVLKVTDYGFNEILIAQGVNTDEEKP P87343_ORYLA P87343_ORYLA VDGRFVLKVTDYGFNEIMNTQEVDVEEEKA Q9W616_ORYLA Q9W616_ORYLA VDGRFVLKVTDYGFNEIMNTQEVDVEEEKA Q4T7P7_TETNG Q4T7P7_TETNG VDGRFVLKITDYGFNEVLDAQRFPYTEPPE Q7T3I2_ORYLA Q7T3I2_ORYLA VDGRFVLKVTDYGYNEVLESQRFPYAEERP Q9W615_ORYLA Q9W615_ORYLA VDGRFVLKVTDYGYNEVLESQRFPYAEERP O57480_CHICK O57480_CHICK VDGRFVLKVTDHGYNELLEAQRVPTPTPQP GUC2E_RAT GUC2E_RAT VDGRFVLKVTDHGHGRLLEAQRVLPEPPSA Q8C8X5_MOUSE Q8C8X5_MOUSE VDGRFVLKVTDHGHGRLLEAQRVLPEPPSA B1ASX7_MOUSE B1ASX7_MOUSE VDGRFVLKVTDHGHGRLLEAQRVLPEPPSA GUC2E_MOUSE GUC2E_MOUSE VDGRFVLKVTDHGHGRLLEAQRVLPEPPSA GUC2D_HUMAN GUC2D_HUMAN VDGRFVLKITDHGHGRLLEAQKVLPEPPRA GUC2D_BOVIN GUC2D_BOVIN VDGRFVLKVTDHGHGRLLEAQRVLPEPPSA GUC2D_CANFA GUC2D_CANFA VDGRFVLKVTDHGHARLMEAQRVLLEPPSA GUC2F_BOVIN GUC2F_BOVIN VDGRFVLKVTDYGFNDILETLRLSQEEPSA GUC2F_HUMAN GUC2F_HUMAN VDGRFVLKVTDYGFNDILEMLRLSEEESSM GUC2F_MOUSE GUC2F_MOUSE VDGRFVLKVTDYGFNDILEMLRLSEEEPSE GUC2F_RAT GUC2F_RAT VDGRFVLKVTDYGFNNILEMLRLSEEEPSE Q9PUK0_RANPI Q9PUK0_RANPI VDGRFVLKITDYGYNEIVEHQKAPRQTSRP B3DHF2_DANRE B3DHF2_DANRE VDGRFVLKITDYGYNEILETQKAPKETLPP Q4SY29_TETNG Q4SY29_TETNG VDGRFVLKITDYGFNELLECQKAPLEEPPP P87342_ORYLA P87342_ORYLA VDGRFVLKITDYGFNELLESQKAPVEEPPP Q9W614_ORYLA Q9W614_ORYLA VDGRFVLKITDYGFNELLESQKAPVEEPPP MATCH ** *****:**:* .: CONSENSUS VDGRFVLK?TD?G????L??Q?????????

GUC2D_RAT GUC2D_RAT ----------------------EELLWTAP Q4TAT8_TETNG Q4TAT8_TETNG GSQQADVKPVAFPGRLSDRACLPELLWVAP P79999_ORYLA P79999_ORYLA ----------------------QDLLWTFP Q7T2Q2_ORYLA Q7T2Q2_ORYLA ----------------------QDLLWTSP A2BFQ0_DANRE A2BFQ0_DANRE ----------------------EDQFWTAP Q4S8Y6_TETNG Q4S8Y6_TETNG ----------------------EDLLWTAP P87343_ORYLA P87343_ORYLA ----------------------EDLLWTAP Q9W616_ORYLA Q9W616_ORYLA ----------------------EDLLWTAP Q4T7P7_TETNG Q4T7P7_TETNG ----------------------DELLWTAP Q7T3I2_ORYLA Q7T3I2_ORYLA ----------------------EELLWTAP Q9W615_ORYLA Q9W615_ORYLA ----------------------EELLWTAP O57480_CHICK O57480_CHICK ----------------------QERLWTAP GUC2E_RAT GUC2E_RAT ----------------------EDQLWTAP Q8C8X5_MOUSE Q8C8X5_MOUSE ----------------------EDQLWTAP B1ASX7_MOUSE B1ASX7_MOUSE ----------------------EDQLWTAP GUC2E_MOUSE GUC2E_MOUSE ----------------------EDQLWTAP GUC2D_HUMAN GUC2D_HUMAN ----------------------EDQLWTAP GUC2D_BOVIN GUC2D_BOVIN ----------------------EDQLWTAP GUC2D_CANFA GUC2D_CANFA ----------------------EDQLWTAP GUC2F_BOVIN GUC2F_BOVIN ----------------------EELLWTAP GUC2F_HUMAN GUC2F_HUMAN ----------------------EELLWTAP GUC2F_MOUSE GUC2F_MOUSE ----------------------EELLWTAP GUC2F_RAT GUC2F_RAT ----------------------EELLWTAP Q9PUK0_RANPI Q9PUK0_RANPI ----------------------GELFWTAP B3DHF2_DANRE B3DHF2_DANRE ----------------------EDLFWTAP Q4SY29_TETNG Q4SY29_TETNG ----------------------EELFWTAP P87342_ORYLA P87342_ORYLA ----------------------EELYWTAP Q9W614_ORYLA Q9W614_ORYLA ----------------------EELYWTAP MATCH : *. * CONSENSUS ??????????????????????????WTAP

GUC2D_RAT GUC2D_RAT ELLRGPRGPWGPGKATFKGDVFSLGIILQE Q4TAT8_TETNG Q4TAT8_TETNG ELLRNPV--QG-G--SFAGDVFSFSIIIQE P79999_ORYLA P79999_ORYLA ELLRNPV--RE-G--SFAGDVFSFSIIIQE Q7T2Q2_ORYLA Q7T2Q2_ORYLA ELLRNPV--RG-G--SFAGDVFSFSIIIQE A2BFQ0_DANRE A2BFQ0_DANRE EILRNPDLKKK-G--TYPGDVYSFSIIMQE Q4S8Y6_TETNG Q4S8Y6_TETNG ELLRNSSLRRK-G--TFTGDIYSFSIVTQE P87343_ORYLA P87343_ORYLA ELLRNLNLRRK-G--SFPGDVYSFAIIMQE Q9W616_ORYLA Q9W616_ORYLA ELLRNLNLRRK-G--SFPGDVYSFAIIMQE Q4T7P7_TETNG Q4T7P7_TETNG EILRMPGQPGVYG--TLPGDVYSFAIIMQE Q7T3I2_ORYLA Q7T3I2_ORYLA EVLRSGQAGLH-G--TLPADVYSFAIIMQE Q9W615_ORYLA Q9W615_ORYLA EVLRSGQAGLH-G--TLPADVYSFAIIMQE O57480_CHICK O57480_CHICK ELLRDAALERR-G--SFRGDVYGIGIIMQE GUC2E_RAT GUC2E_RAT ELLRDPALERR-G--TLAGDVFSLGIIMQE Q8C8X5_MOUSE Q8C8X5_MOUSE ELLRDPSLERR-G--TLAGDVFSLAIIMQE B1ASX7_MOUSE B1ASX7_MOUSE ELLRDPSLERR-G--TLAGDVFSLAIIMQE GUC2E_MOUSE GUC2E_MOUSE ELLRDPSLERR-G--TLAGDVFSLAIIMQE GUC2D_HUMAN GUC2D_HUMAN ELLRDPALERR-G--TLAGDVFSLAIIMQE GUC2D_BOVIN GUC2D_BOVIN ELLRDPVLERR-G--TLAGDVFSLGIIMQE GUC2D_CANFA GUC2D_CANFA ELLRDPALERR-G--TLPGDVFSLGIIMQE GUC2F_BOVIN GUC2F_BOVIN ELLRAPRGSRL-R--SFAGDVYSFAIIMQE GUC2F_HUMAN GUC2F_HUMAN ELLRAPRGSRL-G--SFAGDVYSFAIIMQE GUC2F_MOUSE GUC2F_MOUSE ELLRAPGGIRL-G--SFAGDVYSFAIIMQE GUC2F_RAT GUC2F_RAT ELLRAPGGIRL-G--SFAGDVYSFAIIMQE Q9PUK0_RANPI Q9PUK0_RANPI ELLRDQNLARR-G--TFKGDVFSFAIILQE B3DHF2_DANRE B3DHF2_DANRE EHLRDPESPRK-G--TYKGDVYSFAIILQE Q4SY29_TETNG Q4SY29_TETNG EFLRDITSTRK-G--TSKGDVYSFSIILQE P87342_ORYLA P87342_ORYLA ELLRDLTLFHK-G--TYKGDVYSFSIILQE Q9W614_ORYLA Q9W614_ORYLA ELLRDLTHFHK-G--TYKGDVYSFSIILQE MATCH * ** : .*::.:.*: ** CONSENSUS E?LR????????G?????GDV?S??II?QE

GUC2D_RAT GUC2D_RAT VLTRDPPYCSWGLSAE----EIIRKVASPP Q4TAT8_TETNG Q4TAT8_TETNG VITRSLPYAMMDMPAH----EIVERLKKPP P79999_ORYLA P79999_ORYLA VISRTLPYAMMDMPAH----EIVDRLMKPP Q7T2Q2_ORYLA Q7T2Q2_ORYLA VISRTLPYAMMDMPAH----EIVDRLMKPP A2BFQ0_DANRE A2BFQ0_DANRE VISRCAPFCMLDMPPE----EIIEKVRSPP Q4S8Y6_TETNG Q4S8Y6_TETNG VVCRSAPFCMLDMPAK----EIISKVKVPP P87343_ORYLA P87343_ORYLA VVSRSAPFCMLDMPPK----EIISKVKESP Q9W616_ORYLA Q9W616_ORYLA VVSRSAPFCMLDMPPK----EIISKVKESP Q4T7P7_TETNG Q4T7P7_TETNG VVIRGPPFCTLNLIQCFYVLEILEKLRKPP Q7T3I2_ORYLA Q7T3I2_ORYLA VVIRGPPFCMLDLSDA----EIIEKVRRPP Q9W615_ORYLA Q9W615_ORYLA VVIRGPPFCMLDLSDA----EIIEKVRRPP O57480_CHICK O57480_CHICK VICRSAPYCMLGLPPE----EIIEKVARPP GUC2E_RAT GUC2E_RAT VVCRSTPYAMLELTPE----EVIQRVRSPP Q8C8X5_MOUSE Q8C8X5_MOUSE VVCRSTPYAMLELTPE----GKV------- B1ASX7_MOUSE B1ASX7_MOUSE VVCRSTPYAMLELTPE----EVIQRVRSPP GUC2E_MOUSE GUC2E_MOUSE VVCRSTPYAMLELTPE----EVIQRVRSPP GUC2D_HUMAN GUC2D_HUMAN VVCRSAPYAMLELTPE----EVVQRVRSPP GUC2D_BOVIN GUC2D_BOVIN VVCRSAPYAMLELTPE----EVVKRVQSPP GUC2D_CANFA GUC2D_CANFA VVCRSAPYAMLELTPE----EVVERVRSPP GUC2F_BOVIN GUC2F_BOVIN VMVRGTPFCMMDLPAK----EIIERIKKPP GUC2F_HUMAN GUC2F_HUMAN VMVRGTPFCMMDLPAQ----EIINRLKKPP GUC2F_MOUSE GUC2F_MOUSE VMVRGAPFCMMDLPAK----EIIDRLKMPP GUC2F_RAT GUC2F_RAT VMVRGAPFCMMDLSAK----EVIDRLKMPP Q9PUK0_RANPI Q9PUK0_RANPI VVVRGPPYCMSGLSAE----EIIRKVKKPP B3DHF2_DANRE B3DHF2_DANRE VVVRGAPYCMLGLSPE----EIIRKVKKPP Q4SY29_TETNG Q4SY29_TETNG VVVRGPPYCMLGLPAN----EIIRKVKKPP P87342_ORYLA P87342_ORYLA VVVRGPPYCMLGLPPE----EIIRKVKKPP Q9W614_ORYLA Q9W614_ORYLA VVVRGPPYCMLGLPPE----EIIRKVKKPP MATCH *: * *:. : : CONSENSUS V??R??P??M??????????E???????PP

GUC2D_RAT GUC2D_RAT PLCRPLVSPDQGPLECIQLMQLCWEEAPDD Q4TAT8_TETNG Q4TAT8_TETNG PLCRPLVSVDEAPTECLSLMNECWNEEPSK P79999_ORYLA P79999_ORYLA PLCRPVVSVDEAPAECLNLMNECWNEDPTK Q7T2Q2_ORYLA Q7T2Q2_ORYLA PLCRPVVSVDEAPAECLNLMNECWNEDPTK A2BFQ0_DANRE A2BFQ0_DANRE PLCRPTVSMDEAPLDVIQLMKQAWSEEPEQ Q4S8Y6_TETNG Q4S8Y6_TETNG PLCRPELSVDEAPLDVIQIVKQAWSEEPER P87343_ORYLA P87343_ORYLA PLCRPVVSVEEAPLDIIQLMKQAWSEEPDK Q9W616_ORYLA Q9W616_ORYLA PLCRPVVSVEEAPLDIIQLMKQAWSEEPDK Q4T7P7_TETNG Q4T7P7_TETNG PLCRPVVSPDYAPLECIQLMKQCWSEQPDK Q7T3I2_ORYLA Q7T3I2_ORYLA PLCRPVVSPDYAPMECIQLMKQCWTETPDK Q9W615_ORYLA Q9W615_ORYLA PLCRPVVSPDYAPMECIQLMKQCWTETPDK O57480_CHICK O57480_CHICK PLCRPAVSADQAPLECIHLMKQCWSEQPER GUC2E_RAT GUC2E_RAT PLCRPLVSMDQAPMECIQLMAQCWAEHPEL Q8C8X5_MOUSE Q8C8X5_MOUSE ----------------------VWGQ---- B1ASX7_MOUSE B1ASX7_MOUSE PLCRPLVSMDQAPMECIQLMTQCWAEHPEL GUC2E_MOUSE GUC2E_MOUSE PLCRPLVSMDQAPMECIQLMTQCWAEHPEL GUC2D_HUMAN GUC2D_HUMAN PLCRPLVSMDQAPVECILLMKQCWAEQPEL GUC2D_BOVIN GUC2D_BOVIN PLCRPSVSIDQAPMECIQLMKQCWAEQPEL GUC2D_CANFA GUC2D_CANFA PLCRPSVSMDQAPVECIQLMKQCWAEHPDL GUC2F_BOVIN GUC2F_BOVIN PVYRPVVPPEHAPPECLQLMKQCWAEAAEQ GUC2F_HUMAN GUC2F_HUMAN PVYRPVVPPEHAPPECLQLMKQCWAEAAEQ GUC2F_MOUSE GUC2F_MOUSE PVYRPVVSPEYAPAECLQLMKQCWAEASEQ GUC2F_RAT GUC2F_RAT PVYRPVVSPEFAPPECLQLMKQCWAEAAEQ Q9PUK0_RANPI Q9PUK0_RANPI PLCRPTVGPDQAPWECIQLMKQCWSELPER B3DHF2_DANRE B3DHF2_DANRE PMCRPTVAPDQAPLECIQLMKQCWSEQPDR Q4SY29_TETNG Q4SY29_TETNG PMCRPTVAPDQAPLECIQLMKQCWSELPER P87342_ORYLA P87342_ORYLA PMCRPTVAPDQAPLECIQLMKQCWSEQPDR Q9W614_ORYLA Q9W614_ORYLA PMCRPTVAPDQAPLECIQLMKQCWSEQPDR MATCH * : CONSENSUS P?CRP?V????AP?EC??LM?QCW?E?P??

GUC2D_RAT GUC2D_RAT RPSLDQIYTQFKSINQGKKTSVADSMLRML Q4TAT8_TETNG Q4TAT8_TETNG RPGFNDIFKQFRGINKGKKANIIDSMLRML P79999_ORYLA P79999_ORYLA RPTFDDIFKQFRGISRGRRANIIDSMLRML Q7T2Q2_ORYLA Q7T2Q2_ORYLA RPTFDDIFKQFRGISRGRRANIIDSMLRML A2BFQ0_DANRE A2BFQ0_DANRE RPTFEDIFRQFKSMNKGKKTNIIDSMLRML Q4S8Y6_TETNG Q4S8Y6_TETNG RPTFEEIFKQFKSISRGKKTNIIDSMLRML P87343_ORYLA P87343_ORYLA RPTFEEIFKQFKGNSKAKKTNIIDSMLRML Q9W616_ORYLA Q9W616_ORYLA RPTFEEIFKQFKGNSKAKKTNIIDSMLRML Q4T7P7_TETNG Q4T7P7_TETNG RPAFDEIFDQFKNINKGKKTNIIDSMLRML Q7T3I2_ORYLA Q7T3I2_ORYLA RPTFDDIFDQFKNINKGRKTNIIDSMLRML Q9W615_ORYLA Q9W615_ORYLA RPTFDDIFDQFKNINKGRKTNIIDSMLRML O57480_CHICK O57480_CHICK RPNIDQIFDQFKGINKGRKTNIIDSMLRML GUC2E_RAT GUC2E_RAT RPSMDLTFDLFKGINKGRKTNIIDSMLRML Q8C8X5_MOUSE Q8C8X5_MOUSE ------------------------------ B1ASX7_MOUSE B1ASX7_MOUSE RPSMDLTFDLFKSINKGRKTNIIDSMLRML GUC2E_MOUSE GUC2E_MOUSE RPSMDLTFDLFKSINKGRKTNIIDSMLRML GUC2D_HUMAN GUC2D_HUMAN RPSMDHTFDLFKNINKGRKTNIIDSMLRML GUC2D_BOVIN GUC2D_BOVIN RPSMDRTFELFKSINKGRKMNIIDSMLRML GUC2D_CANFA GUC2D_CANFA RPSLGHIFDQFKSINKGRKTNIIDSMLRML GUC2F_BOVIN GUC2F_BOVIN RPTFDEIFNQFKTFNKGKKTNIIDSMLRML GUC2F_HUMAN GUC2F_HUMAN RPTFDEIFNQFKTFNKGKKTNIIDSMLRML GUC2F_MOUSE GUC2F_MOUSE RPTFDEIFNQFKTFNKGKKTNIIDSMLRML GUC2F_RAT GUC2F_RAT RPTFDEIFNQFKTFNKGKKTNIIDSMLRML Q9PUK0_RANPI Q9PUK0_RANPI RPTFDEIFDQFKTINKGKKTNIIDSMLRML B3DHF2_DANRE B3DHF2_DANRE RPPFDQIFDQFKLINKGKKTNIIDSMLRML Q4SY29_TETNG Q4SY29_TETNG RPTFDEIFDRFKLINKGKKTNIIDSMLRML P87342_ORYLA P87342_ORYLA RPTFEEIFDRFKIINKGKKTNIIDSMLRML Q9W614_ORYLA Q9W614_ORYLA RPTFEEIFDRFKIINKGKKTNIIDSMLRML MATCH CONSENSUS RP?????F??FK???KG?KTNIIDSMLRML

GUC2D_RAT GUC2D_RAT EKYSQSLEGLVQERTEELELERRKTERLLS Q4TAT8_TETNG Q4TAT8_TETNG EQYSSNLEDLIRERTDELEVERTKTDKLVG P79999_ORYLA P79999_ORYLA EQYSSNLEDLIRERTDELEVERNKTEKLVG Q7T2Q2_ORYLA Q7T2Q2_ORYLA EQYSSNLEDLIRERTDELEVERNKTEKLVG A2BFQ0_DANRE A2BFQ0_DANRE EQYSSNLEDLIRERTEELEVERQKTDALLA Q4S8Y6_TETNG Q4S8Y6_TETNG EQYSTNLEDLIRERTEELEVERQKTDKLVA P87343_ORYLA P87343_ORYLA EQYSSNLEDLIRERTEELEVERQKTDNLVA Q9W616_ORYLA Q9W616_ORYLA EQYSSNLEDLIRERTEELEVERQKTDNLVA Q4T7P7_TETNG Q4T7P7_TETNG EQYSSNLEELIRERTEELEIEKQKTEKLLT Q7T3I2_ORYLA Q7T3I2_ORYLA EQYSSNLEELIRERTEELEIEKQKTEKLLT Q9W615_ORYLA Q9W615_ORYLA EQYSSNLEELIRERTEELEIEKQKTEKLLT O57480_CHICK O57480_CHICK EQYSSNLEDLIRERTEELEIEKQKTDKLLT GUC2E_RAT GUC2E_RAT EQYSSNLEDLIRERTEELEQEKQKTDRLLT Q8C8X5_MOUSE Q8C8X5_MOUSE ------------------------------ B1ASX7_MOUSE B1ASX7_MOUSE EQYSSNLEDLIRERTEELEQEKQKTDRLLT GUC2E_MOUSE GUC2E_MOUSE EQYSSNLEDLIRERTEELEQEKQKTDRLLT GUC2D_HUMAN GUC2D_HUMAN EQYSSNLEDLIRERTEELELEKQKTDRLLT GUC2D_BOVIN GUC2D_BOVIN EQYSSNLEDLIRERTEELELEKQKTDRLLT GUC2D_CANFA GUC2D_CANFA EQYSSNLEDLIRERTEELELEKQKTDRLLT GUC2F_BOVIN GUC2F_BOVIN EQYSSNLEDLIQERTEELEIEKQKTEKLLT GUC2F_HUMAN GUC2F_HUMAN EQYSSNLEDLIRERTEELEIEKQKTEKLLT GUC2F_MOUSE GUC2F_MOUSE EQYSSNLEDLIRERTEELEIEKQKTEKLLT GUC2F_RAT GUC2F_RAT EQYSSNLEDLIRERTEELEIEKQKTEKLLT Q9PUK0_RANPI Q9PUK0_RANPI EQYSSNLEDLIRERTEELEVEKQKTEKLSF B3DHF2_DANRE B3DHF2_DANRE EQYSSNLEDLIRERTEELEVEKQRTEKLLS Q4SY29_TETNG Q4SY29_TETNG EQYSSNLEDLIRERTEELEVEKQRTEKLLS P87342_ORYLA P87342_ORYLA EQYSSNLEDLIRERTEELEVEKQRTEKLLS Q9W614_ORYLA Q9W614_ORYLA EQYSSNLEDLIRERTEELEVEKQRTEKLLS MATCH CONSENSUS EQYSSNLEDLIRERTEELE?E?QKT??L??

GUC2D_RAT GUC2D_RAT QMLPP-----------------------SV Q4TAT8_TETNG Q4TAT8_TETNG QLLPK-----------------------SV P79999_ORYLA P79999_ORYLA QLLPK-----------------------SV Q7T2Q2_ORYLA Q7T2Q2_ORYLA QLLPK-----------------------SV A2BFQ0_DANRE A2BFQ0_DANRE QMLPK-----------------------SV Q4S8Y6_TETNG Q4S8Y6_TETNG AMLPK-----------------------SV P87343_ORYLA P87343_ORYLA QMLPK-----------------------SV Q9W616_ORYLA Q9W616_ORYLA QMLPK-----------------------SV Q4T7P7_TETNG Q4T7P7_TETNG QMLPPCVNADEPNQSVHLHGSASSSPFRSV Q7T3I2_ORYLA Q7T3I2_ORYLA QMLPP-----------------------SV Q9W615_ORYLA Q9W615_ORYLA QMLPP-----------------------SV O57480_CHICK O57480_CHICK QMLPP-----------------------SV GUC2E_RAT GUC2E_RAT QMLPP-----------------------SV Q8C8X5_MOUSE Q8C8X5_MOUSE ------------------------------ B1ASX7_MOUSE B1ASX7_MOUSE QMLPP-----------------------SV GUC2E_MOUSE GUC2E_MOUSE QMLPP-----------------------SV GUC2D_HUMAN GUC2D_HUMAN QMLPP-----------------------SV GUC2D_BOVIN GUC2D_BOVIN QMLPP-----------------------SV GUC2D_CANFA GUC2D_CANFA QMLPP-----------------------SV GUC2F_BOVIN GUC2F_BOVIN QMLPP-----------------------SV GUC2F_HUMAN GUC2F_HUMAN QMLPP-----------------------SV GUC2F_MOUSE GUC2F_MOUSE QMLPL-----------------------SV GUC2F_RAT GUC2F_RAT QMLPP-----------------------SV Q9PUK0_RANPI Q9PUK0_RANPI QMLPP-----------------------SV B3DHF2_DANRE B3DHF2_DANRE EMLPP-----------------------SV Q4SY29_TETNG Q4SY29_TETNG EMLPP-----------------------SV P87342_ORYLA P87342_ORYLA EMLPP-----------------------SV Q9W614_ORYLA Q9W614_ORYLA EMLPP-----------------------SV MATCH CONSENSUS ?MLP????????????????????????SV

GUC2D_RAT GUC2D_RAT AHALKMGTTVEPEYFDQVTIYFSDIVGFTT Q4TAT8_TETNG Q4TAT8_TETNG AQALKKGRPVQPEHYSESTLYFSDIVGFTT P79999_ORYLA P79999_ORYLA AQALKKGKPVQPEHYSDCTLYFSDIVGFTT Q7T2Q2_ORYLA Q7T2Q2_ORYLA AQALKKGKPVQPEHYSDCTLYFSDIVGFTT A2BFQ0_DANRE A2BFQ0_DANRE ALALKTGKPVKPEHFAEVTLYFSDIVGFTT Q4S8Y6_TETNG Q4S8Y6_TETNG AKALKTGKPVIPEHFSEVTLYFSDIVGFTT P87343_ORYLA P87343_ORYLA AQSLKLGKPVEPEHFSEVTLYFSDIVGFST Q9W616_ORYLA Q9W616_ORYLA AQSLKLGKPVEPEHFSEVTLYFSDIVGFST Q4T7P7_TETNG Q4T7P7_TETNG AEALKVGGIVEPEHFGSVTIYFSDIVGFTT Q7T3I2_ORYLA Q7T3I2_ORYLA AEALMVGGTVKPEYFDSVSLYFSDIVGFTT Q9W615_ORYLA Q9W615_ORYLA AEALMVGGTVKPEYFDSVSLYFSDIVGFTT O57480_CHICK O57480_CHICK AEALKMGTPVEPEYFEEVTLYFSDIVGFTT GUC2E_RAT GUC2E_RAT AEALKMGTSVEPEYFEEVTLYFSDIVGFTT Q8C8X5_MOUSE Q8C8X5_MOUSE ------------------------------ B1ASX7_MOUSE B1ASX7_MOUSE AEALKMGTSVEPEYFEEVTLYFSDIVGFTT GUC2E_MOUSE GUC2E_MOUSE AEALKMGTSVEPEYFEEVTLYFSDIVGFTT GUC2D_HUMAN GUC2D_HUMAN AEALKTGTPVEPEYFEQVTLYFSDIVGFTT GUC2D_BOVIN GUC2D_BOVIN AEALKMGTPVEPEYFEEVTLYFSDIVGFTT GUC2D_CANFA GUC2D_CANFA AEALKMGTPVEPEYFEEVTLYFSDIVGFTT GUC2F_BOVIN GUC2F_BOVIN AESLKKGCTVEPEGFDLVTLYFSDIVGFTT GUC2F_HUMAN GUC2F_HUMAN AESLKKGCTVEPEGFDLVTLYFSDIVGFTT GUC2F_MOUSE GUC2F_MOUSE AESLKKGCTVEPEGFDLVTLYFSDIVGFTT GUC2F_RAT GUC2F_RAT AESLKKGCTVEPEGFDLVTLYFSDIVGFTT Q9PUK0_RANPI Q9PUK0_RANPI AEALKTGGTVEPEYFDLVTIYFSDIVGFTT B3DHF2_DANRE B3DHF2_DANRE AEALKTGASVEPEYFDQVTIYFSDIVGFTT Q4SY29_TETNG Q4SY29_TETNG AEALKTGGTVEPEYFDQVTIYFSDIVGFTT P87342_ORYLA P87342_ORYLA ADTLKTGATVEPEYFDQVTIYFSDIVGFTT Q9W614_ORYLA Q9W614_ORYLA ADTLKTGATVEPEYFDQVTIYFSDIVGFTT MATCH CONSENSUS A??LK?G??V?PE?F??VT?YFSDIVGFTT

GUC2D_RAT GUC2D_RAT ISALSEPIEVVGFLNDLYTMFDAVLDSHDV Q4TAT8_TETNG Q4TAT8_TETNG ISALSEPIEVVDLLNDLYTMFDAIIATHDV P79999_ORYLA P79999_ORYLA ISALSEPIEVVDLLNDLYTMFDAIIASHDV Q7T2Q2_ORYLA Q7T2Q2_ORYLA ISALSEPIEVVDLLNDLYTMFDAIIASHDV A2BFQ0_DANRE A2BFQ0_DANRE ISALSEPIEVVDLLNDLYTHFDGIIAIHDV Q4S8Y6_TETNG Q4S8Y6_TETNG ISALSEPIEVVDLLNDLYTHFDAIIGLHDV P87343_ORYLA P87343_ORYLA ISTLSEPIEVVDLLNDLYSLFDAIIPLHDV Q9W616_ORYLA Q9W616_ORYLA ISTLSEPIEVVDLLNDLYSLFDAIIPLHDV Q4T7P7_TETNG Q4T7P7_TETNG ISANSEPIEVVDLLNNLYTIFDAIIGNHDV Q7T3I2_ORYLA Q7T3I2_ORYLA ISANSEPIEVVDLLNDLYTLFDAIIGNHDV Q9W615_ORYLA Q9W615_ORYLA ISANSEPIEVVDLLNDLYTLFDAIIGNHDV O57480_CHICK O57480_CHICK ISAMSEPIEVVDLLNDLYTLFDVIIGAHDV GUC2E_RAT GUC2E_RAT ISAMSEPIEVVDLLNDLYTLFDAIIGSHDV Q8C8X5_MOUSE Q8C8X5_MOUSE ------------------------------ B1ASX7_MOUSE B1ASX7_MOUSE ISAMSEPIEVVDLLNDLYTLFDAIIGAHDV GUC2E_MOUSE GUC2E_MOUSE ISAMSEPIEVVDLLNDLYTLFDAIIGAHDV GUC2D_HUMAN GUC2D_HUMAN ISAMSEPIEVVDLLNDLYTLFDAIIGSHDV GUC2D_BOVIN GUC2D_BOVIN ISAMSEPIEVVDLLNDLYTLFDAIIGSHDV GUC2D_CANFA GUC2D_CANFA ISAMSEPIEVVDLLNDLYTLFDAIIGSHDV GUC2F_BOVIN GUC2F_BOVIN ISAMSEPIEVVDLLNDLYTLFDAIIGSHDV GUC2F_HUMAN GUC2F_HUMAN ISAMSEPIEVVDLLNDLYTLFDAIIGSHDV GUC2F_MOUSE GUC2F_MOUSE ISAMSEPIEVVDLLNDLYTLFDAIIGSHDV GUC2F_RAT GUC2F_RAT ISAMSEPIEVVDLLNDLYTLFDAIIGSHDV Q9PUK0_RANPI Q9PUK0_RANPI ISALSEPIEVVDLLNDLYSLFDAVLGNHDV B3DHF2_DANRE B3DHF2_DANRE ISSLSDPIEVVDLLNDLYSLFDAVLGSHDV Q4SY29_TETNG Q4SY29_TETNG ISSLSDPIEVVDLLNDLYSLFDAVLSSHDV P87342_ORYLA P87342_ORYLA ISSLSDPIEVVDLLNDLYTLFDAVLSNHDV Q9W614_ORYLA Q9W614_ORYLA ISSLSDPIEVVDLLNDLYTLFDAVLSNHDV MATCH CONSENSUS IS??SEPIEVVDLLNDLY??FDA????HDV

GUC2D_RAT GUC2D_RAT YKVETIGDAYMVASGLPRRNGNRHAAEIAN Q4TAT8_TETNG Q4TAT8_TETNG YKVETIGDAYMVASGVPNRNGNRHAAEVAN P79999_ORYLA P79999_ORYLA YKVETIGDAYMVASGVPNRNGNRHAAEVSN Q7T2Q2_ORYLA Q7T2Q2_ORYLA YKVETIGDAYMVASGVPNRNGNRHAAEVSN A2BFQ0_DANRE A2BFQ0_DANRE YKVETIGDAYMVASGVPNRNGTRHAAEMAN Q4S8Y6_TETNG Q4S8Y6_TETNG YKVETIGDAYMVASGVPARNGNRHAAEMAN P87343_ORYLA P87343_ORYLA YKVETIGDAYMVASGVPTRNGNRHAAEIAN Q9W616_ORYLA Q9W616_ORYLA YKVETIGDAYMVASGVPTRNGNRHAAEIAN Q4T7P7_TETNG Q4T7P7_TETNG YKVLRLSSFHQTTITSRYQMAASYSA---- Q7T3I2_ORYLA Q7T3I2_ORYLA YKVETIGDAYMVASGVPVPNANRHAAEIAN Q9W615_ORYLA Q9W615_ORYLA YKVETIGDAYMVASGVPVPNANRHAAEIAN O57480_CHICK O57480_CHICK YKVETIGDAYMVASGLPKRNGNRHAGEIAN GUC2E_RAT GUC2E_RAT YKVETIGDAYMVASGLPQRNGQRHAAEIAN Q8C8X5_MOUSE Q8C8X5_MOUSE ------------------------------ B1ASX7_MOUSE B1ASX7_MOUSE YKVETIGDAYMVASGLPQRNGQRHAAEIAN GUC2E_MOUSE GUC2E_MOUSE YKVETIGDAYMVASGLPQRNGQRHAAEIAN GUC2D_HUMAN GUC2D_HUMAN YKVETIGDAYMVASGLPQRNGQRHAAEIAN GUC2D_BOVIN GUC2D_BOVIN YKVETIGDAYMVASGLPQRNGHRHAAEIAN GUC2D_CANFA GUC2D_CANFA YKVETIGDAYMVASGLPQRNGQRHAAEIAN GUC2F_BOVIN GUC2F_BOVIN YKVETIGDAYMVASGLPKRNGMRHAAEIAN GUC2F_HUMAN GUC2F_HUMAN YKVETIGDAYMVASGLPKRNGSRHAAEIAN GUC2F_MOUSE GUC2F_MOUSE YKVETIGDAYMVASGLPKRNGSRHAAEIAN GUC2F_RAT GUC2F_RAT YKVETIGDAYMVASGLPKRNGSRHAAEIAN Q9PUK0_RANPI Q9PUK0_RANPI YKVETIGDAYMVASGLPKRNGNRHAAAIAS B3DHF2_DANRE B3DHF2_DANRE YKVETIGDAYMVASGLPKKNGNKHAAEIAN Q4SY29_TETNG Q4SY29_TETNG YKVETIGDAYMVASGLPKRNGNKHAAEIAN P87342_ORYLA P87342_ORYLA YKVETIGDAYMVASGLPKRNGNKHAAEIAN Q9W614_ORYLA Q9W614_ORYLA YKVETIGDAYMVASGLPKRNGNKHAAEIAN MATCH CONSENSUS YKVETIGDAYMVASG?P?RNG??HAAE?AN

GUC2D_RAT GUC2D_RAT MALEILSYAGNFRMRHAPDVPIRVRAGLHS Q4TAT8_TETNG Q4TAT8_TETNG MSLDILHSIAAFKIKHMPEIKVKIRIGLHS P79999_ORYLA P79999_ORYLA MSLDILHSIGAFKIKHMPEIKVKIRIGLHS Q7T2Q2_ORYLA Q7T2Q2_ORYLA MSLDILHSIGAFKIKHMPEIKVKIRIGLHS A2BFQ0_DANRE A2BFQ0_DANRE MSLDILHCIGTFKMRHMPDVKVKIRIGLHS Q4S8Y6_TETNG Q4S8Y6_TETNG MSLDILHCIGTFKMRHMPDLKVRIRIGLHS P87343_ORYLA P87343_ORYLA MSLDILHCIGTFKARHMPDLKIRIRIGLHS Q9W616_ORYLA Q9W616_ORYLA MSLDILHCIGTFKARHMPDLKIRIRIGLHS Q4T7P7_TETNG Q4T7P7_TETNG -------------------------VGGDH Q7T3I2_ORYLA Q7T3I2_ORYLA MSLDILSAVGTFKMRHMPDVPVRIRIGLHT Q9W615_ORYLA Q9W615_ORYLA MSLDILSAVGTFKMRHMPDVPVRIRIGLHT O57480_CHICK O57480_CHICK MSLDILSSVGTFKMRHMPEVPVRIRIGLHS GUC2E_RAT GUC2E_RAT MSLDILSAVGSFRMRHMPEVPVRIRIGLHS Q8C8X5_MOUSE Q8C8X5_MOUSE ------------------------------ B1ASX7_MOUSE B1ASX7_MOUSE MSLDILSAVGSFRMRHMPEVPVRIRIGLHS GUC2E_MOUSE GUC2E_MOUSE MSLDILSAVGSFRMRHMPEVPVRIRIGLHS GUC2D_HUMAN GUC2D_HUMAN MSLDILSAVGTFRMRHMPEVPVRIRIGLHS GUC2D_BOVIN GUC2D_BOVIN MALDILSAVGTFRMRHMPEVPVRIRIGLHS GUC2D_CANFA GUC2D_CANFA MALDILSAVGSFRMRHMPEVPVRIRIGLHS GUC2F_BOVIN GUC2F_BOVIN MSLDILSSVGTFKMRHMPEVPVRIRIGLHS GUC2F_HUMAN GUC2F_HUMAN MSLDILSSVGTFKMRHMPEVPVRIRIGLHS GUC2F_MOUSE GUC2F_MOUSE MSLDILSSVGTFKMRHMPEVPVRIRIGLHS GUC2F_RAT GUC2F_RAT MSLDILSSVGTFKMRHMPEVPVRIRIGLHT Q9PUK0_RANPI Q9PUK0_RANPI MSLDILSSVGTFQMRHMPDVPVRIRIGLHT B3DHF2_DANRE B3DHF2_DANRE MSLNILSSVGSFKMRHMPEVPVRIRIGIHS Q4SY29_TETNG Q4SY29_TETNG MSLNILSSVGTFHMRHMPDVPVRIRIGIHS P87342_ORYLA P87342_ORYLA MSLNILSSVGSFHMRHMPDVPVRIRIGIHS Q9W614_ORYLA Q9W614_ORYLA MSLNILSSVGSFHMRHMPDVPVRIRIGIHS MATCH CONSENSUS MSL?IL???G?F??RHMP???V?IRIG?H?

GUC2D_RAT GUC2D_RAT GPCVAGVVGLTMPRY----CLFGDTVNTAS Q4TAT8_TETNG Q4TAT8_TETNG GPVVAGVVGLTMPRY----CLFGDTVTTAS P79999_ORYLA P79999_ORYLA GPVVAGVVGLTMPRY----CLFGDTVTTAS Q7T2Q2_ORYLA Q7T2Q2_ORYLA GPVVAGVVGLTMPRY----CLFGDTVTTAS A2BFQ0_DANRE A2BFQ0_DANRE GPVVAGVVGLKMPRY----CLFGDTVNTAS Q4S8Y6_TETNG Q4S8Y6_TETNG GPVVAGVVGLTMPRY----CLFGDTVNTAS P87343_ORYLA P87343_ORYLA GPVVAGVVGLTMPRY----CLFGDTVNTTS Q9W616_ORYLA Q9W616_ORYLA GPVVAGVVGLTMPRY----CLFGDTVNTTS Q4T7P7_TETNG Q4T7P7_TETNG RRCLHGGVGSSCSQWQPPRC--GNSQHVPR Q7T3I2_ORYLA Q7T3I2_ORYLA GPCVAGVVGLTMPRY----CLFGDTVTTAS Q9W615_ORYLA Q9W615_ORYLA GPCVAGVVGLTMPRY----CLFGDTVTTAS O57480_CHICK O57480_CHICK GPCVAGVVGLTMPRY----CLFGDTVNTAS GUC2E_RAT GUC2E_RAT GPCVAGVVGLTMPRY----CLFGDTVNTAS Q8C8X5_MOUSE Q8C8X5_MOUSE ------------------------------ B1ASX7_MOUSE B1ASX7_MOUSE GPCVAGVVGLTMPRY----CLFGDTVNTAS GUC2E_MOUSE GUC2E_MOUSE GPCVAGVVGLTMPRY----CLFGDTVNTAS GUC2D_HUMAN GUC2D_HUMAN GPCVAGVVGLTMPRY----CLFGDTVNTAS GUC2D_BOVIN GUC2D_BOVIN GPCVAGVVGLTMPRY----CLFGDTVNTAS GUC2D_CANFA GUC2D_CANFA GPCVAGVVGLTMPRY----CLFGDTVNTAS GUC2F_BOVIN GUC2F_BOVIN GPVVAGVVGLTMPRY----CLFGDTVNTAS GUC2F_HUMAN GUC2F_HUMAN GPVVAGVVGLTMPRY----CLFGDTVNTAS GUC2F_MOUSE GUC2F_MOUSE GPVVAGVVGLTMPRY----CLFGDTVNTAS GUC2F_RAT GUC2F_RAT GPVVAGVVGLTMPRY----CLFGDTVNTAS Q9PUK0_RANPI Q9PUK0_RANPI GPCVAGVVGLTMPRY----CLFGDTVNTAS B3DHF2_DANRE B3DHF2_DANRE GPCVAGVVGLTMPRY----CLFGDTVNTAS Q4SY29_TETNG Q4SY29_TETNG GACVAGVVGLTMPRY----CLFGDTVNTAS P87342_ORYLA P87342_ORYLA GPCVAGVVGLTMPRY----CLFGDTVNTAS Q9W614_ORYLA Q9W614_ORYLA GPCVAGVVGLTMPRY----CLFGDTVNTAS MATCH CONSENSUS GP?VAGVVGLTMPRY????CLFGDTV?TAS

GUC2D_RAT GUC2D_RAT RMESTG------------------------ Q4TAT8_TETNG Q4TAT8_TETNG HMEASG------------------------ P79999_ORYLA P79999_ORYLA LMESSG------------------------ Q7T2Q2_ORYLA Q7T2Q2_ORYLA LMESSG------------------------ A2BFQ0_DANRE A2BFQ0_DANRE RMESTG------------------------ Q4S8Y6_TETNG Q4S8Y6_TETNG RMESTG------------------------ P87343_ORYLA P87343_ORYLA RMESTS------------------------ Q9W616_ORYLA Q9W616_ORYLA RMESTS------------------------ Q4T7P7_TETNG Q4T7P7_TETNG HSERCR------------------------ Q7T3I2_ORYLA Q7T3I2_ORYLA RMESSG------------------------ Q9W615_ORYLA Q9W615_ORYLA RMESSG------------------------ O57480_CHICK O57480_CHICK RMESTG------------------------ GUC2E_RAT GUC2E_RAT RMESTG------------------------ Q8C8X5_MOUSE Q8C8X5_MOUSE ------------------------------ B1ASX7_MOUSE B1ASX7_MOUSE RMESTG------------------------ GUC2E_MOUSE GUC2E_MOUSE RMESTG------------------------ GUC2D_HUMAN GUC2D_HUMAN RMESTG------------------------ GUC2D_BOVIN GUC2D_BOVIN AMESTG------------------------ GUC2D_CANFA GUC2D_CANFA RMESTG------------------------ GUC2F_BOVIN GUC2F_BOVIN RMESTG------------------------ GUC2F_HUMAN GUC2F_HUMAN RMESTG------------------------ GUC2F_MOUSE GUC2F_MOUSE RMESTG------------------------ GUC2F_RAT GUC2F_RAT RMESTG------------------------ Q9PUK0_RANPI Q9PUK0_RANPI RMESTG------------------------ B3DHF2_DANRE B3DHF2_DANRE RMESTG------------------------ Q4SY29_TETNG Q4SY29_TETNG RMESTGLRRFSSNFSTTVPCCSQFCCVFPT P87342_ORYLA P87342_ORYLA RMESTG------------------------ Q9W614_ORYLA Q9W614_ORYLA RMESTG------------------------ MATCH CONSENSUS ?MES?G????????????????????????

GUC2D_RAT GUC2D_RAT ----LPYRIHVSRNTVQALLSLDEGYKIDV Q4TAT8_TETNG Q4TAT8_TETNG ----LPYRIHISLSTVKVLTSLKLGYHMET P79999_ORYLA P79999_ORYLA ----LPYRIHISLSTVKVLTSLKVGYHIET Q7T2Q2_ORYLA Q7T2Q2_ORYLA ----LPYRIHISLSTVKVLTSLKVGYHIET A2BFQ0_DANRE A2BFQ0_DANRE ----LPYRIHVNQSTVDVLNSLKLGYKIDT Q4S8Y6_TETNG Q4S8Y6_TETNG ----L---------RECLLLNLKLGYKIQV P87343_ORYLA P87343_ORYLA ----SPYRVHVNQSTVNLLNSLKLGYKIDV Q9W616_ORYLA Q9W616_ORYLA ----SPYRVHVNQSTVNLLNSLKLGYKIDV Q4T7P7_TETNG Q4T7P7_TETNG ---NLQNEAHARCSC-------EDTYRVTH Q7T3I2_ORYLA Q7T3I2_ORYLA ----MPYRIHVHESIVKVLKELNLGYKLEL Q9W615_ORYLA Q9W615_ORYLA ----MPYRIHVHESIVKVLKELNLGYKLEL O57480_CHICK O57480_CHICK ----LPYRIHVNARTVAILRALQEGFKLDI GUC2E_RAT GUC2E_RAT ----LPYRIHVNMSTVRILRALDQGFQMEC Q8C8X5_MOUSE Q8C8X5_MOUSE ------------------------------ B1ASX7_MOUSE B1ASX7_MOUSE ----LPYRIHVNMSTVRILRALDQGFQMEC GUC2E_MOUSE GUC2E_MOUSE ----LPYRIHVNMSTVRILRSLDQGFQMEC GUC2D_HUMAN GUC2D_HUMAN ----LPYRIHVNLSTVGILRALDSGYQVEL GUC2D_BOVIN GUC2D_BOVIN ----LPYRIHVNRSTVQILSALNEGFLTEV GUC2D_CANFA GUC2D_CANFA ----LPYRIHVNMSTVRILHALDEGFQTEV GUC2F_BOVIN GUC2F_BOVIN ----LPYRIHVSHSTVTILRTLGEGYEVEL GUC2F_HUMAN GUC2F_HUMAN ----LPYRIHVSLSTVTILQNLSEGYEVEL GUC2F_MOUSE GUC2F_MOUSE ----LPYRIHVSLSTVTILQTLSEGYEVEL GUC2F_RAT GUC2F_RAT ----LPYRIHVSLSTVTILRTLSEGYEVEL Q9PUK0_RANPI Q9PUK0_RANPI ----LPYRIHVNQSTVATLRTLPENYKIEL B3DHF2_DANRE B3DHF2_DANRE ----LPYRIHVNISTVQILRSLNDGYKIDV Q4SY29_TETNG Q4SY29_TETNG CSSLLAYRIHVNMSTVNILHSLNEGYKIQV P87342_ORYLA P87342_ORYLA ----LPYRIHVNMSTVKILRSLNDGYKIDV Q9W614_ORYLA Q9W614_ORYLA ----LPYRIHVNMSTVKILRSLNDGYKIDV MATCH CONSENSUS ????LPYRIH???STV??L??L??G?????

GUC2D_RAT GUC2D_RAT RGQTELKGKGLEETY---WLTGKTGFCRSL Q4TAT8_TETNG Q4TAT8_TETNG R---KAQVKGAVDTY---WLVGRDGFDKPL P79999_ORYLA P79999_ORYLA R---KAQVKGTEDTY---WLMGRDGFNKPL Q7T2Q2_ORYLA Q7T2Q2_ORYLA R---KAQVKGTEDTY---WLMGRDGFNKPL A2BFQ0_DANRE A2BFQ0_DANRE RGRTELKGKGVEETF---WLVGRDGFDKPL Q4S8Y6_TETNG Q4S8Y6_TETNG RGLTELKGKGIENTY---WLVGREDFNKHL P87343_ORYLA P87343_ORYLA RGLTELKGKGIETTY---WLVGKDDFKKSL Q9W616_ORYLA Q9W616_ORYLA RGLTELKGKGIETTY---WLVGKDDFKKSL Q4T7P7_TETNG Q4T7P7_TETNG RSLCRRRGRADNASLLSVWRHGKHRLSHGV Q7T3I2_ORYLA Q7T3I2_ORYLA RGRTEVKGKGTEETY---WLVGRVGFTKPL Q9W615_ORYLA Q9W615_ORYLA RGRTEVKGKGTEETY---WLVGRVGFTKPL O57480_CHICK O57480_CHICK RGKTELKGKGVEDTY---WLVGREGFTKPI GUC2E_RAT GUC2E_RAT RGRTELKGKGVEDTY---WLVGRVGFNKPI Q8C8X5_MOUSE Q8C8X5_MOUSE --------------------IGTL------ B1ASX7_MOUSE B1ASX7_MOUSE RGRTELKGKGIEDTY---WLVGRLGFNKPI GUC2E_MOUSE GUC2E_MOUSE RGRTELKGKGIEDTY---WLVGRLGFNKPI GUC2D_HUMAN GUC2D_HUMAN RGRTELKGKGAEDTF---WLVGRRGFNKPI GUC2D_BOVIN GUC2D_BOVIN RGRTELKGKGAEETY---WLVGRRGFNKPI GUC2D_CANFA GUC2D_CANFA RGRTELKGKGAEDTY---WLVGRRGFNKPI GUC2F_BOVIN GUC2F_BOVIN RGRTELKGKGTEETF---WLVGKKGFTKPL GUC2F_HUMAN GUC2F_HUMAN RGRTELKGKGTEETF---WLIGKKGFMKPL GUC2F_MOUSE GUC2F_MOUSE RGRTELKGKGTEETF---WLVGKKGFTKPL GUC2F_RAT GUC2F_RAT RGRTELKGKGTEETF---WLVGKKGFTKPL Q9PUK0_RANPI Q9PUK0_RANPI RGKTELKGKGIEETF---WLVGKDGFNKPL B3DHF2_DANRE B3DHF2_DANRE RGKTELKGKGIEETY---WLVGKANFTKPL Q4SY29_TETNG Q4SY29_TETNG RGKTELKGKGIEETY---WLVGKTDFAKPL P87342_ORYLA P87342_ORYLA RGKTELKGKGIEETY---WLVGKTNFSKPL Q9W614_ORYLA Q9W614_ORYLA RGKTELKGKGIEETY---WLVGKTNFSKPL MATCH * CONSENSUS RG?TE?KGKG?E?T????WL?G???F?K??

GUC2D_RAT GUC2D_RAT --PTPLSIQPGDP---W-----QDHINQEI Q4TAT8_TETNG Q4TAT8_TETNG --PVPPDLTGGAS---N-HGISLDEIPVER P79999_ORYLA P79999_ORYLA --PVPPDLIGGAS---N-HGIALDEIPVER Q7T2Q2_ORYLA Q7T2Q2_ORYLA --PVPPDLIGGAS---N-HGIALDEIPVER A2BFQ0_DANRE A2BFQ0_DANRE --PIPPDLTPGAS---N-HGISLDEIPTDR Q4S8Y6_TETNG Q4S8Y6_TETNG --PVPPDI---------------------- P87343_ORYLA P87343_ORYLA --PVPLDLQ-GGT---D-FGITIEEIPPDR Q9W616_ORYLA Q9W616_ORYLA --PVPLDLQ-GGT---D-FGITIEEIPPDR Q4T7P7_TETNG Q4T7P7_TETNG QWSAEKDLRRRTG---WSAGMDLPNLCQFP Q7T3I2_ORYLA Q7T3I2_ORYLA --PVPPELKTGMK---A-----PRDMKQVF Q9W615_ORYLA Q9W615_ORYLA --PVPPELKTGMK---A-----PRDMKQVF O57480_CHICK O57480_CHICK --PTPPDLLPGAS---N-HGISLDEIPAER GUC2E_RAT GUC2E_RAT --PKPPDLQPGAS---N-HGISLQEIPPER Q8C8X5_MOUSE Q8C8X5_MOUSE ------------------------------ B1ASX7_MOUSE B1ASX7_MOUSE --PKPPDLQPGAS---N-HGISLQEIPPER GUC2E_MOUSE GUC2E_MOUSE --PKPPDLQPGAS---N-HGISLQEIPPER GUC2D_HUMAN GUC2D_HUMAN --PKPPDLQPGSS---N-HGISLQEIPPER GUC2D_BOVIN GUC2D_BOVIN --PKPPDLQPGAS---N-HGISLHEIPPDR GUC2D_CANFA GUC2D_CANFA --PKPPDLQPGAS---N-HGISLQEIPLDR GUC2F_BOVIN GUC2F_BOVIN --PVPPPVGKDGQ---VGHGLQSVEIAAFQ GUC2F_HUMAN GUC2F_HUMAN --PVPPPVDKDGQ---VGHGLQPVEIAAFQ GUC2F_MOUSE GUC2F_MOUSE --PVPPPVGKDGQ---VGHGLQPAEIAAFQ GUC2F_RAT GUC2F_RAT --PVPPPVGKDGQ---VGHGLQPAEIAAFQ Q9PUK0_RANPI Q9PUK0_RANPI --PKPPDIKPGCI---A-HGLTAEEISEFK B3DHF2_DANRE B3DHF2_DANRE --PNPPEIKPGDN---W-QDMMTEEIKSLF Q4SY29_TETNG Q4SY29_TETNG --PKPPDIKPGVN---W-QEMVTEEIKTLF P87342_ORYLA P87342_ORYLA --PKPPEIKPRGQLARNGDGGNQDSFPPGQ Q9W614_ORYLA Q9W614_ORYLA --PKPPEIKPGDN---W-QEMVTEEIKTLF MATCH CONSENSUS ??P?PP????????????????????????

GUC2D_RAT GUC2D_RAT RTGFAKLAR-VC------------------ Q4TAT8_TETNG Q4TAT8_TETNG RQK--------------------------- P79999_ORYLA P79999_ORYLA RQKFLDRQK-LIKK---------------- Q7T2Q2_ORYLA Q7T2Q2_ORYLA RQKFLDRQK-LIKK---------------- A2BFQ0_DANRE A2BFQ0_DANRE RQKFLDRQK-RMGN---------------- Q4S8Y6_TETNG Q4S8Y6_TETNG ------------------------------ P87343_ORYLA P87343_ORYLA RQKFLDRQK-KA------------------ Q9W616_ORYLA Q9W616_ORYLA RQKFLDRQK-KA------------------ Q4T7P7_TETNG Q4T7P7_TETNG PKSSLGKWPTGCRWPR-------------- Q7T3I2_ORYLA Q7T3I2_ORYLA HKAVKKISH-VRVVTQLHMPEDDANVMMTH Q9W615_ORYLA Q9W615_ORYLA HKAVKKISH-VRVVTQLHMPEDDANVMMTH O57480_CHICK O57480_CHICK RRKLEKARP-GQVLK--------------- GUC2E_RAT GUC2E_RAT RKKLEKARP-GQFTGK-------------- Q8C8X5_MOUSE Q8C8X5_MOUSE ------------------------------ B1ASX7_MOUSE B1ASX7_MOUSE RKKLEKARP-GQFTGK-------------- GUC2E_MOUSE GUC2E_MOUSE RKKLEKARP-GQFTGK-------------- GUC2D_HUMAN GUC2D_HUMAN RRKLEKARP-GQFS---------------- GUC2D_BOVIN GUC2D_BOVIN RQKLEKARP-GQFSGK-------------- GUC2D_CANFA GUC2D_CANFA RWKLEKARP-GQFSGK-------------- GUC2F_BOVIN GUC2F_BOVIN RRKQKSSW---------------------- GUC2F_HUMAN GUC2F_HUMAN RRKAERQLV-RNKP---------------- GUC2F_MOUSE GUC2F_MOUSE RRKAERQLV-RNKP---------------- GUC2F_RAT GUC2F_RAT RRKAERQLV-RNKP---------------- Q9PUK0_RANPI Q9PUK0_RANPI RRKAEKLLS-KKEAEGGLAGNGNQGN---- B3DHF2_DANRE B3DHF2_DANRE RKANRPVDK-HKI----------------- Q4SY29_TETNG Q4SY29_TETNG RKANRQVDK-KL------------------ P87342_ORYLA P87342_ORYLA QTSAQNVLKTGREDNIPKMELLRRQRSIRM Q9W614_ORYLA Q9W614_ORYLA RQANRPVHKMF------------------- MATCH CONSENSUS ??????????????????????????????

GUC2D_RAT GUC2D_RAT ----------- Q4TAT8_TETNG Q4TAT8_TETNG ----------- P79999_ORYLA P79999_ORYLA ----------- Q7T2Q2_ORYLA Q7T2Q2_ORYLA ----------- A2BFQ0_DANRE A2BFQ0_DANRE ----------- Q4S8Y6_TETNG Q4S8Y6_TETNG ----------- P87343_ORYLA P87343_ORYLA ----------- Q9W616_ORYLA Q9W616_ORYLA ----------- Q4T7P7_TETNG Q4T7P7_TETNG ----------- Q7T3I2_ORYLA Q7T3I2_ORYLA H---------- Q9W615_ORYLA Q9W615_ORYLA H---------- O57480_CHICK O57480_CHICK ----------- GUC2E_RAT GUC2E_RAT ----------- Q8C8X5_MOUSE Q8C8X5_MOUSE ----------- B1ASX7_MOUSE B1ASX7_MOUSE ----------- GUC2E_MOUSE GUC2E_MOUSE ----------- GUC2D_HUMAN GUC2D_HUMAN ----------- GUC2D_BOVIN GUC2D_BOVIN ----------- GUC2D_CANFA GUC2D_CANFA ----------- GUC2F_BOVIN GUC2F_BOVIN ----------- GUC2F_HUMAN GUC2F_HUMAN ----------- GUC2F_MOUSE GUC2F_MOUSE ----------- GUC2F_RAT GUC2F_RAT ----------- Q9PUK0_RANPI Q9PUK0_RANPI ----------- B3DHF2_DANRE B3DHF2_DANRE ----------- Q4SY29_TETNG Q4SY29_TETNG ----------- P87342_ORYLA P87342_ORYLA RMDLETKRSKS Q9W614_ORYLA Q9W614_ORYLA ----------- MATCH CONSENSUS ???????????


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