Alignment of the gene Family HBG104815 of HOVERGEN

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Threshold: 50% 80% 100%
Size: Bigger Smaller Normal
Isoforms are ON
B7ZCT7_MOUSE B7ZCT7_MOUSE --------------SSDRIRMCGINEERRAPLSDEESTTGGCQHFGSQEFCVSSSFSKVE BCORL_MOUSE BCORL_MOUSE ISTAPLYSGVHNWTSSDRIRMCGINEERRAPLSDEESTTGGCQHFGSQEFCVSSSFSKVE B5MDQ8_HUMAN B5MDQ8_HUMAN ISTAPLYSGVHNWTSSDRIRMCGINEERRAPLSDEESTTGDCQHFGSQEFCVSSSFSKVE BCORL_HUMAN BCORL_HUMAN ISTAPLYSGVHNWTSSDRIRMCGINEERRAPLSDEESTTGDCQHFGSQEFCVSSSFSKVE B4F6U5_XENTR B4F6U5_XENTR LSAAPLYSGVHNWTSVDRVRMCGINEDRRTSLSDEESKTSCSQHRGSEDHCVNSFLSKVE Q6GN44_XENLA Q6GN44_XENLA ------------------------------------------------------------ MATCH CONSENSUS ??????????????S?DR?RMCGINE?RR??LSDEES?T???QH?GS???CV?S??SKVE

B7ZCT7_MOUSE B7ZCT7_MOUSE LTAVGSGSNARGTNPDGNTTEKLGHRSEDQSDDPQPKMDYVGNPAEAEGLLVPLSSPGDG BCORL_MOUSE BCORL_MOUSE LTAVGSGSNARGTNPDGNTTEKLGHRSEDQSDDPQPKMDYVGNPAEAEGLLVPLSSPGDG B5MDQ8_HUMAN B5MDQ8_HUMAN LTAVGSGSNARGADPDGSATEKLGHKSEDKPDDPQPKMDYAGNVAEAEGFLVPLSSPGDG BCORL_HUMAN BCORL_HUMAN LTAVGSGSNARGADPDGSATEKLGHKSEDKPDDPQPKMDYAGNVAEAEGFLVPLSSPGDG B4F6U5_XENTR B4F6U5_XENTR FTSGAKQSDALMLQEDGGAVET-GQRLEEKPPD-------------------PILTPGDT Q6GN44_XENLA Q6GN44_XENLA ------------------------------------------------------------ MATCH CONSENSUS ?T?????S?A?????DG???E??G???E????D???????????????????P???PGD?

B7ZCT7_MOUSE B7ZCT7_MOUSE LKLPTPDSTEASHSRANCSWTPLSTQMSKQVDCSPAGVKALDSRHGVGEKNTFILATLGT BCORL_MOUSE BCORL_MOUSE LKLPTPDSTEASHSRANCSWTPLSTQMSKQVDCSPAGVKALDSRHGVGEKNTFILATLGT B5MDQ8_HUMAN B5MDQ8_HUMAN LKLPASDSAEASNSRADCSWTPLNTQMSKQVDCSPAGVKALDSRQGVGEKNTFILATLGT BCORL_HUMAN BCORL_HUMAN LKLPASDSAEASNSRADCSWTPLNTQMSKQVDCSPAGVKALDSRQGVGEKNTFILATLGT B4F6U5_XENTR B4F6U5_XENTR VVPKVHDNTLPSDSK----------QVTNMLDISIQATSTPDSKR--------------- Q6GN44_XENLA Q6GN44_XENLA ------------------------------------------------------------ MATCH CONSENSUS ??????D????S?S???????????Q?????D?S???????DS?????????????????

B7ZCT7_MOUSE B7ZCT7_MOUSE GVPVEGTLPLVTTNFSQLPAPICPPAPGSASGTPSVPDPFQVPLSVPAPVPHSGLVPVQV BCORL_MOUSE BCORL_MOUSE GVPVEGTLPLVTTNFSQLPAPICPPAPGSASGTPSVPDPFQVPLSVPAPVPHSGLVPVQV B5MDQ8_HUMAN B5MDQ8_HUMAN GVPVEGTLPLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQV BCORL_HUMAN BCORL_HUMAN GVPVEGTLPLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQV B4F6U5_XENTR B4F6U5_XENTR --------------------------------TESARAPVPEKSSLPADADHSGLQKNVL Q6GN44_XENLA Q6GN44_XENLA ------------------------------------------------------------ MATCH CONSENSUS ??????????????????????????????????S?????????S?PA???HSGL?????

B7ZCT7_MOUSE B7ZCT7_MOUSE ATSASAPSPPL------APAAPSVPTLISDSNPLSVSASVLVPVPVSAPHSVPVPLSAPA BCORL_MOUSE BCORL_MOUSE ATSASAPSPPL------APAAPSVPTLISDSNPLSVSASVLVPVPVSAPHSVPVPLSAPA B5MDQ8_HUMAN B5MDQ8_HUMAN ATSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAPA BCORL_HUMAN BCORL_HUMAN ATSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAPA B4F6U5_XENTR B4F6U5_XENTR AAGLQSVGQQM------------------------------------------------- Q6GN44_XENLA Q6GN44_XENLA ------------------------------------------------------------ MATCH CONSENSUS A???????????????????????????????????????????????????????????

B7ZCT7_MOUSE B7ZCT7_MOUSE PTPLTVSVSAPPLALIQAPVPPSAPTLVLASVPTPVLAPMPASTPPAAPAPPSVPMPTPT BCORL_MOUSE BCORL_MOUSE PTPLTVSVSAPPLALIQAPVPPSAPTLVLASVPTPVLAPMPASTPPAAPAPPSVPMPTPT B5MDQ8_HUMAN B5MDQ8_HUMAN PAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTPT BCORL_HUMAN BCORL_HUMAN PAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTPT B4F6U5_XENTR B4F6U5_XENTR ------------------------------------------------------------ Q6GN44_XENLA Q6GN44_XENLA ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

B7ZCT7_MOUSE B7ZCT7_MOUSE PSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSLSRVC BCORL_MOUSE BCORL_MOUSE PSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSLSRVC B5MDQ8_HUMAN B5MDQ8_HUMAN PSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSLSRVC BCORL_HUMAN BCORL_HUMAN PSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSLSRVC B4F6U5_XENTR B4F6U5_XENTR -------------------------------------EASHTVVSSSFGTLTPFAMSRIC Q6GN44_XENLA Q6GN44_XENLA ------------------------------------------------------------ MATCH CONSENSUS ??????????????????????????????????????A???????S??????F??SR?C

B7ZCT7_MOUSE B7ZCT7_MOUSE FPAAQAPAMQKVPLSFQPGTVLTPNQPLVYIPPPSCGQPLSVATLPTTLGVSSTLTLPVL BCORL_MOUSE BCORL_MOUSE FPAAQAPAMQKVPLSFQPGTVLTPNQPLVYIPPPSCGQPLSVATLPTTLGVSSTLTLPVL B5MDQ8_HUMAN B5MDQ8_HUMAN FPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSSTLTLPVL BCORL_HUMAN BCORL_HUMAN FPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSSTLTLPVL B4F6U5_XENTR B4F6U5_XENTR FSTTQVPNVQKLPLSFTPGAVLSPSQPLVYIPPPNCGQPLGVATLPTTFGVTSTLTLPML Q6GN44_XENLA Q6GN44_XENLA -----------------------PTRP--------------------------------- MATCH *.:* CONSENSUS F???Q?P??QK?PLSF?PG?VL?P?QPLVYIPPP?CGQPL?VATLPTT?GV?STLTLP?L

B7ZCT7_MOUSE B7ZCT7_MOUSE PSYLQDRCLPGVLASPDLRSYPCAFSVARPLASDSKLVSLEVNRLSCTSPS-SSTNSQPA BCORL_MOUSE BCORL_MOUSE PSYLQDRCLPGVLASPDLRSYPCAFSVARPLASDSKLVSLEVNRLSCTSPS-SSTNSQPA B5MDQ8_HUMAN B5MDQ8_HUMAN PSYLQDRCLPGVLASPELRSYPYAFSVARPLTSDSKLVSLEVNRLPCTSPS-GSTTTQPA BCORL_HUMAN BCORL_HUMAN PSYLQDRCLPGVLASPELRSYPYAFSVARPLTSDSKLVSLEVNRLPCTSPS-GSTTTQPA B4F6U5_XENTR B4F6U5_XENTR PPCLQERCLPSIIAPTELHAHTFTSPLGRPLTTDPKVTSTELNKSASTTASISATDRHSI Q6GN44_XENLA Q6GN44_XENLA ---------------------------------------TKLNKSASTTASISATDRHSV MATCH ::*: ..*:.* .:* :. CONSENSUS P??LQ?RCLP???A???L??????????RPL??D?K??S?E?N????T??S???T?????

B7ZCT7_MOUSE B7ZCT7_MOUSE PDGVPGPLADTSLTTASAKVLPTSQLLLPAPSGSSVP----PHPSKMPGGTDQQTEGTSV BCORL_MOUSE BCORL_MOUSE PDGVPGPLADTSLTTASAKVLPTSQLLLPAPSGSSVP----PHPSKMPGGTDQQTEGTSV B5MDQ8_HUMAN B5MDQ8_HUMAN PDGVPGPLADTSLVTASAKVLPTPQPLLPAPSGSSAP----PHPAKMPSGTEQQTEGTSV BCORL_HUMAN BCORL_HUMAN PDGVPGPLADTSLVTASAKVLPTPQPLLPAPSGSSAP----PHPAKMPSGTEQQTEGTSV B4F6U5_XENTR B4F6U5_XENTR TTAVDGSSICTDPTSTSISTLQTLSSHSSHPVVSVNPVTLAPY-SRTSTTLEQQNDSVSS Q6GN44_XENLA Q6GN44_XENLA TTAVDGSPICTDPTSTSISTLQTLSSHSPHPLVSVSPVTLAPY-NRTSTTLEQQNDSVSS MATCH . .* *. *. .::* ..* * . . * * * *: : . :**.:..* CONSENSUS ???V?G????T?????S???L?T?????P?P??S??P????P??????????QQ????S?

B7ZCT7_MOUSE B7ZCT7_MOUSE TFSPLKSPPQLEREMASPPECSEMPLDLSAKSNRQKLPLPNQRKTPPMPVLTPVHTSSKA BCORL_MOUSE BCORL_MOUSE TFSPLKSPPQLEREMASPPECSEMPLDLSAKSNRQKLPLPNQRKTPPMPVLTPVHTSSKA B5MDQ8_HUMAN B5MDQ8_HUMAN TFSPLKSPPQLEREMASPPECSEMPLDLSSKSNRQKLPLPNQRKTPPMPVLTPVHTSSKA BCORL_HUMAN BCORL_HUMAN TFSPLKSPPQLEREMASPPECSEMPLDLSSKSNRQKLPLPNQRKTPPMPVLTPVHTSSKA B4F6U5_XENTR B4F6U5_XENTR SISPLKSPPQLEREMISPQDTCEMPLDLSSKSHRHKHTPSNQRKTPPMPVLTPVHTSGKA Q6GN44_XENLA Q6GN44_XENLA SISPLKSPPQLEREIISPQDTCEMPLDLSSKSHRHKHTPTNQRKTPPMPVLTPVHTSGKA MATCH ::************: ** : .*******:**:*:* . .*****************.** CONSENSUS ??SPLKSPPQLEREM?SP????EMPLDLS?KS?R?K????NQRKTPPMPVLTPVHTS?KA

B7ZCT7_MOUSE B7ZCT7_MOUSE LLSTVLSRSQRTTQA------AGSNVTSCLGSTSSPFVIFPEMVRNGDPST--------- BCORL_MOUSE BCORL_MOUSE LLSTVLSRSQRTTQA------AGSNVTSCLGSTSSPFVIFPEMVRNGDPST--------- B5MDQ8_HUMAN B5MDQ8_HUMAN LLSTVLSRSQRTTQA------AGGNVTSCLGSTSSPFVIFPEIVRNGDPST--------- BCORL_HUMAN BCORL_HUMAN LLSTVLSRSQRTTQA------AGGNVTSCLGSTSSPFVIFPEIVRNGDPST--------- B4F6U5_XENTR B4F6U5_XENTR LLTTVLSRSDCNTQRPTPNSFTSSSVNQSL-RAAPPLVMFPDFLRNGDPGSSQLLGATGS Q6GN44_XENLA Q6GN44_XENLA SLTTVLSRSDCNTQRPTPNSFTSSSVNQSL-RAAPPLVMFPDFLRNGDPGSSQLLGATGA MATCH *:******: .** :...*...* ::.*:*:**:::*****.: CONSENSUS LL?TVLSRS???TQ???????????V???L?????P?V?FP???RNGDP???????????

B7ZCT7_MOUSE B7ZCT7_MOUSE WVKNSTALISTIPGTYVGVANPVPASLLLNKDPNLGLNRDPRHLPKQEPISIIDQGEPKS BCORL_MOUSE BCORL_MOUSE WVKNSTALISTIPGTYVGVANPVPASLLLNKDPNLGLNRDPRHLPKQEPISIIDQGEPKS B5MDQ8_HUMAN B5MDQ8_HUMAN WVKNSTALISTIPGTYVGVANPVPASLLLNKDPNLGLNRDPRHLPKQEPISIIDQGEPKG BCORL_HUMAN BCORL_HUMAN WVKNSTALISTIPGTYVGVANPVPASLLLNKDPNLGLNRDPRHLPKQEPISIIDQGEPKG B4F6U5_XENTR B4F6U5_XENTR WIKNSAALISTIPGTYVGVANPVPASVLLNKDSNMSLSTDSRHMAKQEPISIIDQGEPKN Q6GN44_XENLA Q6GN44_XENLA WIKNSAALISTIPGTYVGVANPVPASVLLNKDSNMSLSTDSRHMAKQEPISIIDQGEPKN MATCH *:***:********************:*****.*:.*. *.**:.**************. CONSENSUS W?KNS?ALISTIPGTYVGVANPVPAS?LLNKD?N??L??D?RH??KQEPISIIDQGEPK?

B7ZCT7_MOUSE B7ZCT7_MOUSE TSATCGKKGSQAGAEGQPSTVKSRYTPARIAPGLPGCQTKELSLWKPTGLTNMYPRCSIN BCORL_MOUSE BCORL_MOUSE TSATCGKKGSQAGAEGQPSTVKSRYTPARIAPGLPGCQTKELSLWKPTGLTNMYPRCSIN B5MDQ8_HUMAN B5MDQ8_HUMAN TGATCGKKGSQAGAEGQPSTVK-RYTPARIAPGLPGCQTKELSLWKPTGPANIYPRCSVN BCORL_HUMAN BCORL_HUMAN TGATCGKKGSQAGAEGQPSTVK-RYTPARIAPGLPGCQTKELSLWKPTGPANIYPRCSVN B4F6U5_XENTR B4F6U5_XENTR SGP-CGKKANQNSVDGQQSTTK-RYPHGRVPSVTSLCTSKDWTL----GHGGIHPKCPLN Q6GN44_XENLA Q6GN44_XENLA SGP-CGMKANQNSVDGQQSTTK-RYPHGHVTSVTSLCPSKDWTL----GHGGIHPKFPLN MATCH :.. ** *..* ..:** **.* **. .::.. . * :*: :* * .::*: .:* CONSENSUS ????CGKK??Q????GQ?ST?K?RY???R???????C??K???L????G?????P?C??N

B7ZCT7_MOUSE B7ZCT7_MOUSE GKPTSTQVLPVGWSPYHQASLLSIGISSAGQLTPSQGVPIR-PTSIVSEFSGVSPLGSSE BCORL_MOUSE BCORL_MOUSE GKPTSTQVLPVGWSPYHQASLLSIGISSAGQLTPSQGVPIR-PTSIVSEFSGVSPLGSSE B5MDQ8_HUMAN B5MDQ8_HUMAN GKPTSTQVLPVGWSPYHQASLLSIGISSAGQLTPSQGAPIR-PTSVVSEFSGVPSLSSSE BCORL_HUMAN BCORL_HUMAN GKPTSTQVLPVGWSPYHQASLLSIGISSAGQLTPSQGAPIR-PTSVVSEFSGVPSLSSSE B4F6U5_XENTR B4F6U5_XENTR GKPTNAQVMPVSWSSYHQASLLSIGVSTTGTINASQGATHRLPISEYTLFPNILPADTNV Q6GN44_XENLA Q6GN44_XENLA GKPTNAQVMPVSWSPYHQTSLLSIGVSTTGTINANQGATHRLPISEYTLFPSILPADTNV MATCH ****.:**:**.**.***:******:*::* :...**.. * * * : *..: . .:. CONSENSUS GKPT??QV?PV?WSPYHQASLLSIG?S??G????SQG???R?P?S????F??????????

B7ZCT7_MOUSE B7ZCT7_MOUSE TVH-----GLPEGQPRPGGPFAPEQDAVTKNKNCRIAAKPYEEQVNPVLLTLSPQSGTLA BCORL_MOUSE BCORL_MOUSE TVH-----GLPEGQPRPGGPFAPEQDAVTKNKNCRIAAKPYEEQVNPVLLTLSPQSGTLA B5MDQ8_HUMAN B5MDQ8_HUMAN AVH-----GLPEGQPRPGGSFVPEQDPVTKNKTCRIAAKPYEEQVNPVLLTLSPQTGTLA BCORL_HUMAN BCORL_HUMAN AVH-----GLPEGQPRPGGSFVPEQDPVTKNKTCRIAAKPYEEQVNPVLLTLSPQTGTLA B4F6U5_XENTR B4F6U5_XENTR TLQKTGNENHSDTKQINTGASVLEHEQITRGVACEAFSKPRKSNAKKTLAPK-PAAGNSV Q6GN44_XENLA Q6GN44_XENLA TLQTTSNENHSDTKQINTGATAPEHEKFARRIACEAFSKPRTSNAKKTLAPK-PAAGNSV MATCH ::: . .: : *. . *:: .:: *. :** .:.: .* . * :*. . CONSENSUS ??????????????????G???PE????T????C????KP????????L????P??G???

B7ZCT7_MOUSE B7ZCT7_MOUSE LSVQPSSGDMGVN-----QGSEE-------SESHLCSDSTPKMEGPQAACGLKLAGDTKP BCORL_MOUSE BCORL_MOUSE LSVQPSSGDMGVN-----QGSEE-------SESHLCSDSTPKMEGPQAACGLKLAGDTKP B5MDQ8_HUMAN B5MDQ8_HUMAN LSVQPSGGDIRMN-----QGPEE-------SESHLCSDSTPKMEGPQGACGLKLAGDTKP BCORL_HUMAN BCORL_HUMAN LSVQPSGGDIRMN-----QGPEE-------SESHLCSDSTPKMEGPQGACGLKLAGDTKP B4F6U5_XENTR B4F6U5_XENTR LHLQPSATE-RIDTTDNLQGANSSITLKKVSDKKNCKDEKIR---PKLTYNRKRFGETKP Q6GN44_XENLA Q6GN44_XENLA LLLQPTATK-RTDTTDNLQGANSSITLKKVSDKQNCKDEKIH---PKLNHNRKPFGETKP MATCH * :**:. . : **.:. *:.: *.*.. : *: . * *:*** CONSENSUS L??QPS????????????QG??????????S????C?D???????P??????K??G?TKP

B7ZCT7_MOUSE B7ZCT7_MOUSE KNQVLATYMSHELVLANPQNLCKMPELPLLPHDSHSKELILDVV--------PSSERGPS BCORL_MOUSE BCORL_MOUSE KNQVLATYMSHELVLANPQNLCKMPELPLLPHDSHSKELILDVV--------PSSERGPS B5MDQ8_HUMAN B5MDQ8_HUMAN KNQVLATYMSHELVLATPQNLPKMPELPLLPHDSHPKELILDVV--------PSSRRGSS BCORL_HUMAN BCORL_HUMAN KNQVLATYMSHELVLATPQNLPKMPELPLLPHDSHPKELILDVV--------PSSRRGSS B4F6U5_XENTR B4F6U5_XENTR KNKVLATYMTHDQPVTQQKD---TLSLSLLDQGCSKDTSEADISHDQQSPAKQNHKRGHK Q6GN44_XENLA Q6GN44_XENLA KNKVLATYMTHDKPVTQQKD-----SLSLIDQGCSKGTSGADVSHYQQSPAKQSRKRGHK MATCH **:******:*: :: :: .*.*: :.. *: . .** . CONSENSUS KN?VLATYM?H???????????????L?LL???????????DV??????????S??RG??

B7ZCT7_MOUSE B7ZCT7_MOUSE TDLSQLGSQVDLGRVKMEKADGDVVF-NLANCFRADGLPAVPQRGQAEARANAGQARVKR BCORL_MOUSE BCORL_MOUSE TDLSQLGSQVDLGRVKMEKADGDVVF-NLANCFRADGLPAVPQRGQAEARANAGQARVKR B5MDQ8_HUMAN B5MDQ8_HUMAN TERPQLGSQVDLGRVKMEKVDGDVVF-NLATCFRADGLPVAPQRGQAEVRAKAGQARVKQ BCORL_HUMAN BCORL_HUMAN TERPQLGSQVDLGRVKMEKVDGDVVF-NLATCFRADGLPVAPQRGQAEVRAKAGQARVKQ B4F6U5_XENTR B4F6U5_XENTR EETLHCVQEVDLSKVKIERVEDDENFGHISTC---NNLSWSPVDIPAITKVK---TRIKK Q6GN44_XENLA Q6GN44_XENLA VETLQSVQEVDLSKVKIERVDDDENFGHISTC---NNLSWSPVDIPAITKVK---TRIKK MATCH : : .:***.:**:*:.:.* * :::.* :.*. * * .:.: :*:*: CONSENSUS ????Q????VDL??VK?E??D?D??F?????C?????L???P????A?????????R?K?

B7ZCT7_MOUSE B7ZCT7_MOUSE ESIGVFTCKNSWQPDEETESLPPKKVKCNKEKEIEEEPRQQPPPQPHDKPMVRSSLGSKC BCORL_MOUSE BCORL_MOUSE ESIGVFTCKNSWQPDEETESLPPKKVKCNKEKEIEEEPRQQPPPQPHDKPMVRSSLGSKC B5MDQ8_HUMAN B5MDQ8_HUMAN ESVGVFACKNKWQPDDVTESLPPKKMKCGKEKDSEEQ-----QLQPQAKAVVRSSHRPKC BCORL_HUMAN BCORL_HUMAN ESVGVFACKNKWQPDDVTESLPPKKMKCGKEKDSEEQ-----QLQPQAKAVVRSSHRPKC B4F6U5_XENTR B4F6U5_XENTR EP-GV-RCRSK-RLEELAPSKPNQQKSKHKIKRREEEVNKTEQDTSKRK----------W Q6GN44_XENLA Q6GN44_XENLA EP-GL-RCHSK-RLEELTPSKPNQQKSKHKVKQKEEEINKTGQDTPKRK----------W MATCH *. *: *:.. : :: : * * :: . * * **: .: * CONSENSUS E??GV??C?????????T?S?P???????K?K??EE?????????P??K???????????

B7ZCT7_MOUSE B7ZCT7_MOUSE RKLPGDPQEPTKKSPRGALDSGKEHNGVRGKHKHRKPTKPESQPPGKRTDGHEEGSLEKK BCORL_MOUSE BCORL_MOUSE RKLPGDPQEPTKKSPRGALDSGKEHNGVRGKHKHRKPTKPESQPPGKRTDGHEEGSLEKK B5MDQ8_HUMAN B5MDQ8_HUMAN RKLPSDPQESTKKSPRGASDSGKEHNGVRGKHKHRKPTKPESQSPGKRADSHEEGSLEKK BCORL_HUMAN BCORL_HUMAN RKLPSDPQESTKKSPRGASDSGKEHNGVRGKHKHRKPTKPESQSPGKRADSHEEGSLEKK B4F6U5_XENTR B4F6U5_XENTR KNKPTTAQAGTEKKDCKNPGSEKEKMGIRPKRRKRKYIKSEPLDP-----ELDRAITEKK Q6GN44_XENLA Q6GN44_XENLA KRKSPTTQAVAEKKDIKKPGSEKEKTGIRPKRRRRKHIKSEPLDP-----ELDGAINEKK MATCH :. . .* ::*. .* **: *:* *:::** *.*. * : . *** CONSENSUS ???P???Q??T?K???????S?KE??G?R?K???RK??K?E???P????????????EKK

B7ZCT7_MOUSE B7ZCT7_MOUSE AKNSFRDFIPVVLSTRTRSQSGSICSSFAGMADSDMGSQEVFPTEEEEEVAPTPAKRRKV BCORL_MOUSE BCORL_MOUSE AKNSFRDFIPVVLSTRTRSQSGSICSSFAGMADSDMGSQEVFPTEEEEEVAPTPAKRRKV B5MDQ8_HUMAN B5MDQ8_HUMAN AKSSFRDFIPVVLSTRTRSQS--------------------------------------- BCORL_HUMAN BCORL_HUMAN AKSSFRDFIPVVLSTRTRSQSGSICSSFAGMADSDMGSQEVFPTEEEEEVTPTPAKRRKV B4F6U5_XENTR B4F6U5_XENTR SKNSFRDFIPVVLKSRTRSQTG-----NSGSSDVASSFADTYSGVQEED-HDVPCKRRKL Q6GN44_XENLA Q6GN44_XENLA SKNSFRDFIPVVLKSRTRSQTG-----YSGSSDVASSFADSYAVVQEEE-HDVPCKRRKL MATCH :*.**********.:*****: CONSENSUS ?K?SFRDFIPVVL??RTRSQ?G???????G??D?????????????EE?????P?KRRK?

B7ZCT7_MOUSE B7ZCT7_MOUSE RKTQRDTQY-RSHHAQDKTLLSQGRRHLWRAREMPWRTEAARQMWDTNEEEEDDEEEGLV BCORL_MOUSE BCORL_MOUSE RKTQRDTQY-RSHHAQDKTLLSQGRRHLWRAREMPWRTEAARQMWDTNEEEEDDEEEGLV B5MDQ8_HUMAN B5MDQ8_HUMAN ------------------------------------------------------------ BCORL_HUMAN BCORL_HUMAN RKTQRDTQY-RSHHAQDKSLLSQGRRHLWRAREMPWRTEAARQMWDTNEEEEEEEEEGLL B4F6U5_XENTR B4F6U5_XENTR RKILKACRHSRFTAAKEEPQLEPITPVLRGSWDVSNRVSDLGKAWPLLKDDEEADEDSPF Q6GN44_XENLA Q6GN44_XENLA RKIQKTCRHSRFTAVKEEPQLEPITPVLRGSWDVTNRVSDAGKAWPLLDKDEEADEDGPF MATCH CONSENSUS RK????????R?????????L??????L????????R???????W??????E???E????

B7ZCT7_MOUSE B7ZCT7_MOUSE KRKKRRRQKSRKYQTGEYLIEQEEQ-------RRKGRADSKARKQKT-SSQSSEHCLRNR BCORL_MOUSE BCORL_MOUSE KRKKRRRQKSRKYQTGEYLIEQEEQ-------RRKGRADSKARKQKT-SSQSSEHCLRNR B5MDQ8_HUMAN B5MDQ8_HUMAN --------------------------------------DLKARKQKTSSSQSLEHRLRNR BCORL_HUMAN BCORL_HUMAN KRKKRRRQKSRKYQTGEYLTEQEDEQ------RRKGRADLKARKQKTSSSQSLEHRLRNR B4F6U5_XENTR B4F6U5_XENTR RRRKRRRQKNRKYQNGEYLTEKEEEEVSQCYRRQKVSTDLRKRKHS--PSDDSIKTFRNK Q6GN44_XENLA Q6GN44_XENLA RRRKRRRQKNRKYQNGEYLTEKQEEEVSHCYRRRKVRTDLHKRKHS--PSDKPIKTFRNK MATCH * : **:. .*:. : :**: CONSENSUS ?R?KRRRQK?RKYQ?GEYL?E???????????R?K???D???RK?????S???????RN?

B7ZCT7_MOUSE B7ZCT7_MOUSE NLLLSSKAQGISDSPNGFLPDNLEEPACLENPEKPSGKRKCKTKHMANASEE---AR--- BCORL_MOUSE BCORL_MOUSE NLLLSSKAQGISDSPNGFLPDNLEEPACLENPEKPSGKRKCKTKHMANASEE---ARSKG B5MDQ8_HUMAN B5MDQ8_HUMAN NLLLPNKVQGISDSPNGFLPNNLEEPACLENSEKPSGKRKCKTKHMATVSEE---AK--- BCORL_HUMAN BCORL_HUMAN NLLLPNKVQGISDSPNGFLPNNLEEPACLENSEKPSGKRKCKTKHMATVSEE---AK--- B4F6U5_XENTR B4F6U5_XENTR LSSSSRESPKQSNTRNCSRKGSPEESPAPQNTEKPSGKRKCKTKHLGGSKDEEVKGKTRR Q6GN44_XENLA Q6GN44_XENLA LSSSSRESPKQSNARNCSHNGNPEESPTPQK-EKPSGKRKCKTKHIGGSLDAEVKGKTRR MATCH . : *:: * .. **.. :: *************:. : .: CONSENSUS ???????????S???N?????N?EE?????N?EKPSGKRKCKTKH??????E????????

B7ZCT7_MOUSE B7ZCT7_MOUSE ------------------------------------------------------------ BCORL_MOUSE BCORL_MOUSE RWSQQKTRSSKSPTPVKPTEPCTPSKYRSAGPEEASESPTARQIPPEARRLIVNKNAGET B5MDQ8_HUMAN B5MDQ8_HUMAN ------------------------------------------------------------ BCORL_HUMAN BCORL_HUMAN ------------------------------------------------------------ B4F6U5_XENTR B4F6U5_XENTR NNQSPKSTPLKSPSSRKSKDPDTPCRSRRTSTLGSSDTPSAQHIPPEARRLIVNKNAGET Q6GN44_XENLA Q6GN44_XENLA NSQSPKSSPLKSPSSRKSRDPDTPCRSRRTSTLGSSDTPSAQHIPPEARRLIVNKNAGET MATCH CONSENSUS ????????????????????????????????????????????????????????????

B7ZCT7_MOUSE B7ZCT7_MOUSE -----------DVVLYCLQKHSEDVNHRDNAGYTALHEACSRGWTDILNILLQHGANVNC BCORL_MOUSE BCORL_MOUSE LLQRAARLGYKDVVLYCLQKHSEDVNHRDNAGYTALHEACSRGWTDILNILLQHGANVNC B5MDQ8_HUMAN B5MDQ8_HUMAN -----------DVVLYCLQKDSEDVNHRDNAGYTALHEACSRGWTDILNILLEHGANVNC BCORL_HUMAN BCORL_HUMAN -----------DVVLYCLQKDSEDVNHRDNAGYTALHEACSRGWTDILNILLEHGANVNC B4F6U5_XENTR B4F6U5_XENTR LLQRAARLGYKDVVLYCLQRDLGDINHRDNAGYTALHEACARGWTDILQILLDNGANVNC Q6GN44_XENLA Q6GN44_XENLA LLQRAARLGYKDVVLYCLQRDLGDINHRDNAGYTALHEACARGWTDILQLLLDNGANVNC MATCH ********:. *:***************:*******::**::****** CONSENSUS ???????????DVVLYCLQ????D?NHRDNAGYTALHEAC?RGWTDIL?ILL??GANVNC

B7ZCT7_MOUSE B7ZCT7_MOUSE SSQDGTRPVHDAVVNDNLETIWLLLSYGADPTLATYSGQTAMKLASSDNMKRFLSDHLSD BCORL_MOUSE BCORL_MOUSE SSQDGTRPVHDAVVNDNLETIWLLLSYGADPTLATYSGQTAMKLASSDNMKRFLSDHLSD B5MDQ8_HUMAN B5MDQ8_HUMAN SAQDGTRPVHDAVVNDNLETIWLLLSYGADPTLATYSGQTAMKLASSDTMKRFLSDHLSD BCORL_HUMAN BCORL_HUMAN SAQDGTRPVHDAVVNDNLETIWLLLSYGADPTLATYSGQTAMKLASSDTMKRFLSDHLSD B4F6U5_XENTR B4F6U5_XENTR SAQDGTRPIHDAVVNDNLETVWLLLSYGADPTLATYSGQTPMKLASSEIMRKFLSNYLGD Q6GN44_XENLA Q6GN44_XENLA SAQDGTRPIHDAVVNDNLETVWLLLSYGADPTLATYSGQTPMKLASSKIMRKFLSNYLGD MATCH *:******:***********:*******************.******. *::***::*.* CONSENSUS S?QDGTRP?HDAVVNDNLET?WLLLSYGADPTLATYSGQT?MKLASS??M??FLS??L?D

B7ZCT7_MOUSE B7ZCT7_MOUSE LQGRAEGDPRASWDFYSSSVLEKKDGFACDLLHNPPGSAEQGDDSE-----QDDFMFELS BCORL_MOUSE BCORL_MOUSE LQGRAEGDPRASWDFYSSSVLEKKDGFACDLLHNPPGSAEQGDDSE-----QDDFMFELS B5MDQ8_HUMAN B5MDQ8_HUMAN LQGRAEGDPGVSWDFYSSSVLEEKDGFACDLLHNPPGSSDQEGDDPME---EDDFMFELS BCORL_HUMAN BCORL_HUMAN LQGRAEGDPGVSWDFYSSSVLEEKDGFACDLLHNPPGSSDQEGDDPME---EDDFMFELS B4F6U5_XENTR B4F6U5_XENTR LRGHSDGDPHASWDFYSSSVLGGKDEVGHDILLDTSNISDEEEEQEGDKDLEDNFLFEFS Q6GN44_XENLA Q6GN44_XENLA LRGHSDGDPNASWDFYSSSILGGKDEVGHDIVLDTSYISEEDEEQEEDKDLEDNFLFEFS MATCH *:*:::*** .********:* ** .. *:: :.. ::: :. :*:*:**:* CONSENSUS L?G???GDP??SWDFYSSSVL??KD????D?L????????????????????D?F?FE?S

B7ZCT7_MOUSE B7ZCT7_MOUSE DKPLLPCYNLQVSVSRGPCNWFLFSDVLKRLKLSSRIFQARFPHLEITTLPKAEFYRQVA BCORL_MOUSE BCORL_MOUSE DKPLLPCYNLQVSVSRGPCNWFLFSDVLKRLKLSSRIFQARFPHLEITTLPKAEFYRQVA B5MDQ8_HUMAN B5MDQ8_HUMAN DKPLLPCYNLQVSVSRGPCNWFLFSDVLKRLKLSSRIFQARFPHFEITTMPKAEFYRQVA BCORL_HUMAN BCORL_HUMAN DKPLLPCYNLQVSVSRGPCNWFLFSDVLKRLKLSSRIFQARFPHFEITTMPKAEFYRQVA B4F6U5_XENTR B4F6U5_XENTR DRPLLSCYNLHVSLTSGPSNWLLFSDVLKRLKLSSRIFQARYPHFEIASMQKKEFTKQVL Q6GN44_XENLA Q6GN44_XENLA DKPLLYCYNLHVSLTSGPSNWFLFSDVLKHLKLSSRIFQARHPHFEVARMQKKEFTKQVL MATCH *:*** ****:**:: **.**:*******:***********.**:*:: : * ** :** CONSENSUS DKPLL?CYNL?VS???GP?NWFLFSDVLKRLKLSSRIFQAR?PH?EI????K?EF??QV?

B7ZCT7_MOUSE B7ZCT7_MOUSE SSQLLSPAERPGSLEDRSPPGSSETVELVQYEPELLRLLGSEVEYQSWSS BCORL_MOUSE BCORL_MOUSE SSQLLSPAERPGSLEDRSPPGSSETVELVQYEPELLRLLGSEVEYQSWSS B5MDQ8_HUMAN B5MDQ8_HUMAN SSQLLTPAERPGGLDDRSPPGSSETVELVRYEPDLLRLLGSEVEFQSCNS BCORL_HUMAN BCORL_HUMAN SSQLLTPAERPGGLDDRSPPGSSETVELVRYEPDLLRLLGSEVEFQSCNS B4F6U5_XENTR B4F6U5_XENTR TSQLLTPTE---GLDLW-PQDMGDIVELVKYEPELLQLLGSAVEFQGVSS Q6GN44_XENLA Q6GN44_XENLA TSQLLTPTE---GLDLW-PQDMGDIVELVKYEPELLRLLGSAVEFQGVSS MATCH :****:*:* .*: * . .: ****:***:**:**** **:*. .* CONSENSUS ?SQLL?P?E????L????P??????VELV?YEP?LLRLLGS?VE?Q???S


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