Alignment of the gene Family HBG104975 of HOVERGEN

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Isoforms are ON
Q8WNY4_SHEEP Q8WNY4_SHEEP ------------------------------------------------------------ Q9CVP4_MOUSE Q9CVP4_MOUSE ------------------------------------------------------------ Q9DE31_XENLA Q9DE31_XENLA -----------------IVLLLSLMAASHSNMRTN------------------------- Q4RE84_TETNG Q4RE84_TETNG ------------------------------------------------------------ B0S5M2_DANRE B0S5M2_DANRE ------------------------------------------------------------ Q4SUT7_TETNG Q4SUT7_TETNG --------------------MDQMSSDLRRRRAEAQEEEAAEGGPASVFVMNQLNERLET Q58EQ1_DANRE Q58EQ1_DANRE ERYQLSVLCWWTFLISTVVDWRGVDGNNPFYRP--------------------------- Q7ZZU8_DANRE Q7ZZU8_DANRE ERYQLSVLCWWTFLISTVVDWRGVDGNNPFYRP--------------------------- B5X3B3_SALSA B5X3B3_SALSA EQLRFSAFWCGTILFGSILLEQKMASSMT------------------------------- B2RFG8_SPAAU B2RFG8_SPAAU ------------------------------------------------------------ Q4S0V9_TETNG Q4S0V9_TETNG ------------------------------------------------------------ TGFR2_CHICK TGFR2_CHICK MPPRLRPLL-L-----RVSLWVLVGSSSPALLHDR------------------------- TGFR2_PIG TGFR2_PIG GRGLLGGLWPL-----HVVLWTRIASTIPPHVPKS------------------------- A3QNQ0_HUMAN A3QNQ0_HUMAN GRGLLRGLWPL-----HIVLWTRIASTIPPHVQKS------------------------- TGFR2_HUMAN TGFR2_HUMAN GRGLLRGLWPL-----HIVLWTRIASTIPPHVQKS------------------------- B4DTV5_HUMAN B4DTV5_HUMAN GRGLLRGLWPL-----HIVLWTRIASTIPPHVQKSDVEMEAQKDEIICPSCNRTAHPLRH B4E2S6_HUMAN B4E2S6_HUMAN ------------------------------------------------------------ TGFR2_RAT TGFR2_RAT GRGLLRGLWPL-----HIVLWTRIASTIPPHVPKS------------------------- Q91ZR8_MOUSE Q91ZR8_MOUSE GRGLLRGLWPL-----HIVLWTRIASTIPPHVPKS------------------------- Q3UG22_MOUSE Q3UG22_MOUSE GRGLLRGLWPL-----HIVLWTRIASTIPPHVPKS------------------------- Q8BRS2_MOUSE Q8BRS2_MOUSE GRGLLRGLWPL-----HIVLWTRIASTIPPHVPKSDVEMEAQKDASIHLSCNRTIHPLKH Q543C0_MOUSE Q543C0_MOUSE GRGLLRGLWPL-----HIVLWTRIASTIPPHVPKSDVEMEAQKDASIHLSCNRTIHPLKH TGFR2_MOUSE TGFR2_MOUSE GRGLLRGLWPL-----HIVLWTRIASTIPPHVPKSDVEMEAQKDASIHLSCNRTIHPLKH Q8BQS9_MOUSE Q8BQS9_MOUSE GRGLLRGLWPL-----HIVLWTRIASTIPPHVPKSDVEMEAQKDASIHVSCNRTIHPLKH MATCH CONSENSUS ????????????????????????????????????????????????????????????

Q8WNY4_SHEEP Q8WNY4_SHEEP ------------------------------------------------------------ Q9CVP4_MOUSE Q9CVP4_MOUSE ------------------------------------------------------------ Q9DE31_XENLA Q9DE31_XENLA -----------------------VCKWCDNSHPVCDG-GICLTNCSLSSYCENPEEICVT Q4RE84_TETNG Q4RE84_TETNG -----------------------------------------MSNSSKPSDHHTAQRPLYF B0S5M2_DANRE B0S5M2_DANRE -----------------------LCKWCDHSSPVCED-NVCMSNCSLTSYCFLAEEVCVA Q4SUT7_TETNG Q4SUT7_TETNG FRNLLPNRLNLPAGMPGFLPLNQLCKFCDVEPSSCSGTGTCGSSCNITSICQLPEEVCVA Q58EQ1_DANRE Q58EQ1_DANRE ------------------YRIPQLCKFCDVLESNCNGKDTCESNCSITSICESPDEICVA Q7ZZU8_DANRE Q7ZZU8_DANRE ------------------YRIPQLCKFCDVLESNCNGKDTCESNCSITSICESPDEICVA B5X3B3_SALSA B5X3B3_SALSA -----------------MLKLKRLCKFCDVESTSCTGTGSCMTDCSITSICPHPEDVCVS B2RFG8_SPAAU B2RFG8_SPAAU ------------------------------------------------------------ Q4S0V9_TETNG Q4S0V9_TETNG ------------------LKMSKLCKFCDVRATSCTGIGSCTVGCEITSTCADKEEVCVS TGFR2_CHICK TGFR2_CHICK -------------SKENGLQLPRLCKFCDVKATTCSNQDQCKSNCNITSICEKNNEVCAA TGFR2_PIG TGFR2_PIG VNSDM-----MVTDSNGAVKLPQLCKFCDVRSSTCDNQKSCLSNCSITAICEKPQEVCVA A3QNQ0_HUMAN A3QNQ0_HUMAN VNNDM-----IVTDNNGAVKFPQLCKFCDVRFSTCDNQKSCMSNCSITSICEKPQEVCVA TGFR2_HUMAN TGFR2_HUMAN VNNDM-----IVTDNNGAVKFPQLCKFCDVRFSTCDNQKSCMSNCSITSICEKPQEVCVA B4DTV5_HUMAN B4DTV5_HUMAN INNDM-----IVTDNNGAVKFPQLCKFCDVRFSTCDNQKSCMSNCSITSICEKPQEVCVA B4E2S6_HUMAN B4E2S6_HUMAN ------------------------------------------------------------ TGFR2_RAT TGFR2_RAT VNSDL-----MAGDNSGAVKLPQLCKFCDVTLSTCDNQKSCMSNCSVTSICEKPQEVCVA Q91ZR8_MOUSE Q91ZR8_MOUSE VNSDV-----MASDNGGAVKLPQLCKFCDVRLSTCDNQRSCMSNCSITAICEKPHEVCVA Q3UG22_MOUSE Q3UG22_MOUSE VNSDV-----MASDNGGAVKLPQLCKFCDVRLSTCDNQKSCMSNCSITAICEKPHEVCVA Q8BRS2_MOUSE Q8BRS2_MOUSE FNSDV-----MASDNGGAVKLPQLCKFCDVRLSTCDNQKSCMSNCSITAICEKPHEVCVA Q543C0_MOUSE Q543C0_MOUSE FNSDV-----MASDNGGAVKLPQLCKFCDVRLSTCDNQKSCMSNCSITAICEKPHEVCVA TGFR2_MOUSE TGFR2_MOUSE FNSDV-----MASDNGGAVKLPQLCKFCDVRLSTCDNQKSCMSNCSITAICEKPHEVCVA Q8BQS9_MOUSE Q8BQS9_MOUSE FNSDV-----MASDNGGAVKLPQLCKFCDVRLSTCDNQKSCMSNCSITAICEKPHEVCVA MATCH CONSENSUS ????????????????????????????????????????????????????????????

Q8WNY4_SHEEP Q8WNY4_SHEEP ------------------------------------------------------------ Q9CVP4_MOUSE Q9CVP4_MOUSE ------------------------------------------------------------ Q9DE31_XENLA Q9DE31_XENLA IWKEENESLQLSTRCHHPLLLLENF---LVPNYNTSLCVMSAMPSVSGRLYTCACTEEQE Q4RE84_TETNG Q4RE84_TETNG PRRKTNETTTVHTTCHNPALPLEGISPALLLNFTSRECHMTSQPAEGATLMVCGCRGEHE B0S5M2_DANRE B0S5M2_DANRE IWKKDNVSVSVRTLCYDPQHMLENI---MLANYSSKECLMSPHPSEDGLLFICSCVGDQE Q4SUT7_TETNG Q4SUT7_TETNG IWRKNETGFFMETLCHDPSKSLYGL---MLDDHNSSTCVMREKNTTSGTAHVCSCRAE-E Q58EQ1_DANRE Q58EQ1_DANRE IWRQSDDNNTIETLCHNPTVPLYGI---MVENNNNTKCEMKKRISNSGPFHICSCNEV-E Q7ZZU8_DANRE Q7ZZU8_DANRE IWRQSDDNNTIETLCHNPTVPLYGI---MVENNNNTKCEMKKRISNSGPFHICSCNEV-E B5X3B3_SALSA B5X3B3_SALSA IWRKKDDNVTIDTICHNPAHKLHGL---VLEDYNNSKCEMRERNGMGSQFFICSCSED-E B2RFG8_SPAAU B2RFG8_SPAAU ------------------------------------------------------------ Q4S0V9_TETNG Q4S0V9_TETNG IWRKAGSNVTFDTVCHNPAYKLYGL---VLDDYNNSKCEMKEIKGMGSKFFICSCSTD-E TGFR2_CHICK TGFR2_CHICK VWRRNDENVTLETICHDPQKRLYGH---MLDDSSSEQCVMKEKKDDGGLMFMCSCTGE-E TGFR2_PIG TGFR2_PIG VWRKNDENITIETVCDDPKIAYHGF---VLDDAASSKCIMKERKGSGETFFMCSCSSD-E A3QNQ0_HUMAN A3QNQ0_HUMAN VWRKNDENITLETVCHDPKLPYHDF---ILEDAASPKCIMKEKKKPGETFFMCSCSSD-E TGFR2_HUMAN TGFR2_HUMAN VWRKNDENITLETVCHDPKLPYHDF---ILEDAASPKCIMKEKKKPGETFFMCSCSSD-E B4DTV5_HUMAN B4DTV5_HUMAN VWRKNDENITLETVCHDPKLPYHDF---ILEDAASPKCIMKEKKKPGETFFMCSCSSD-E B4E2S6_HUMAN B4E2S6_HUMAN ---------------------------------------------------MCSCSSD-E TGFR2_RAT TGFR2_RAT VWRKNDKNITLETVCHDPKFTYHGF---TLEDATSPTCVMKEKKRAGETFFMCSCNTE-E Q91ZR8_MOUSE Q91ZR8_MOUSE VWRKNDKNITLETVCHDPKLTYHGF---TLEDAASPKCVMKEKKRAGETFFMCACNME-E Q3UG22_MOUSE Q3UG22_MOUSE VWRKNDKNITLETVCHDPKLTYHGF---TLEDAASPKCVMKEKKRAGETFFMCACNME-E Q8BRS2_MOUSE Q8BRS2_MOUSE VWRKNDKNITLETVCHDPKLTYHGF---TLEDAASPKCVMKEKKRAGETFFMCACNME-E Q543C0_MOUSE Q543C0_MOUSE VWRKNDKNITLETVCHDPKLTYHGF---TLEDAASPKCVMKEKKRAGETFFMCACNME-E TGFR2_MOUSE TGFR2_MOUSE VWRKNDKNITLETVCHDPKLTYHGF---TLEDAASPKCVMKEKKRAGETFFMCACNME-E Q8BQS9_MOUSE Q8BQS9_MOUSE VWRKNDKNITLETVCHDPKLTYHGF---TLEDAASPKCVMKEKKRAGETFFMCACNME-E MATCH CONSENSUS ????????????T?C??P???????????????????C?M????????????C?C????E

Q8WNY4_SHEEP Q8WNY4_SHEEP ------------------------------------------------------------ Q9CVP4_MOUSE Q9CVP4_MOUSE ------------------------------------------------------------ Q9DE31_XENLA Q9DE31_XENLA CNDQLIFYN--------------------------------------------------- Q4RE84_TETNG Q4RE84_TETNG CNDKLIFDQ--------------------------------------------------- B0S5M2_DANRE B0S5M2_DANRE CNDRLIFDK--------------------------------------------------- Q4SUT7_TETNG Q4SUT7_TETNG CNDVLSFSPAERDFEKVPSAETSPARRSRTGCRLFSSHRARSDSWPLSGPAGTPASEEAV Q58EQ1_DANRE Q58EQ1_DANRE CNDMLLFKL--------------------------------------------------- Q7ZZU8_DANRE Q7ZZU8_DANRE CNDMLLF----------------------------------------------------- B5X3B3_SALSA B5X3B3_SALSA CNDHLFFTP--------------------------------------------------- B2RFG8_SPAAU B2RFG8_SPAAU ------------------------------------------------------------ Q4S0V9_TETNG Q4S0V9_TETNG CNEHIFF----------------------------------------------------- TGFR2_CHICK TGFR2_CHICK CNDVLIFS---------------------------------------------------- TGFR2_PIG TGFR2_PIG CNDHIIFSE--------------------------------------------------- A3QNQ0_HUMAN A3QNQ0_HUMAN CNDNIIFSE--------------------------------------------------- TGFR2_HUMAN TGFR2_HUMAN CNDNIIFSE--------------------------------------------------- B4DTV5_HUMAN B4DTV5_HUMAN CNDNIIFSE--------------------------------------------------- B4E2S6_HUMAN B4E2S6_HUMAN CNDNIIFSE--------------------------------------------------- TGFR2_RAT TGFR2_RAT CNDYIIFNE--------------------------------------------------- Q91ZR8_MOUSE Q91ZR8_MOUSE CNDYIIFSE--------------------------------------------------- Q3UG22_MOUSE Q3UG22_MOUSE CNDYIIFSE--------------------------------------------------- Q8BRS2_MOUSE Q8BRS2_MOUSE CNDYIIFSE--------------------------------------------------- Q543C0_MOUSE Q543C0_MOUSE CNDYIIFSE--------------------------------------------------- TGFR2_MOUSE TGFR2_MOUSE CNDYIIFSE--------------------------------------------------- Q8BQS9_MOUSE Q8BQS9_MOUSE CNDYIIFSE--------------------------------------------------- MATCH CONSENSUS CND???F?????????????????????????????????????????????????????

Q8WNY4_SHEEP Q8WNY4_SHEEP ------------------------------------------------------------ Q9CVP4_MOUSE Q9CVP4_MOUSE ------------------------------------------------------------ Q9DE31_XENLA Q9DE31_XENLA -----------QSNGFSMLHSKEVVPVAAISLLPPFLCAVMVTVLFYLYRTQRLSKIP-- Q4RE84_TETNG Q4RE84_TETNG -----------GANGFSKLQNKDLVPVVLVSLVPPLLVAVAATLAFYFYRTRQVDKPDSP B0S5M2_DANRE B0S5M2_DANRE -----------GPNGFSKLKSKDVIPVVVISLVPPLLVAVIATMAFYLYRTRQPGKKP-- Q4SUT7_TETNG Q4SUT7_TETNG MLAESAKAADSEDTVVDPTPEDSLVSVVLVSLLPLLVMGVVIGAMFYWYRVHRPRMHS-- Q58EQ1_DANRE Q58EQ1_DANRE -----------------PTNNQ-VVLVILVSLLPLLVLAVLVIASFYWYRLYRRRKLD-- Q7ZZU8_DANRE Q7ZZU8_DANRE ----------------KLPTNNQVVLVILVSLLPLLVLAVLVIASFYWYRMYRRRKLD-- B5X3B3_SALSA B5X3B3_SALSA -----------------YSLDSQVVSVVLVSLVPLLVLAVMVITSFYWYRIYHQRRAG-- B2RFG8_SPAAU B2RFG8_SPAAU ------------------------------------------------------------ Q4S0V9_TETNG Q4S0V9_TETNG ----------------NPTTNSEVVTVVLVSLVPLLVMAVVVIASFYCYRIYRQRKAS-- TGFR2_CHICK TGFR2_CHICK -----------AIDPHKPEEKDEISKVTIISLVPLLVISVAVIVIFYAYRTHKKRKLN-- TGFR2_PIG TGFR2_PIG -----------EYATNNPDLLLVIFQVTGVSLLPPLGIAIAVIITFYCYRVHRQQKLS-- A3QNQ0_HUMAN A3QNQ0_HUMAN -----------EYNTSNPDLLLVIFQVTGISLLPPLGVAISVIIIFYCYRVNRQQKLS-- TGFR2_HUMAN TGFR2_HUMAN -----------EYNTSNPDLLLVIFQVTGISLLPPLGVAISVIIIFYCYRVNRQQKLS-- B4DTV5_HUMAN B4DTV5_HUMAN -----------EYNTSNPDLLLVIFQVTGISLLPPLGVAISVIIIFYCYRVNRQQKLS-- B4E2S6_HUMAN B4E2S6_HUMAN -----------EYNTSNPDLLLVIFQVTGISLLPPLGVAISVIIIFYCYRVNRQQKLS-- TGFR2_RAT TGFR2_RAT -----------EYTTSSPDLLLVIIQVTGVSLLPPLGIAIAVIAIFYCYRVHRQQKLS-- Q91ZR8_MOUSE Q91ZR8_MOUSE -----------EYTTSSPDLLLVIIQVTGVSLLPPLGIAIAVIIIFYCYRVHRQQKLS-- Q3UG22_MOUSE Q3UG22_MOUSE -----------EYTTSSPDLLLVIIQVTGVSLLPPLGIAIAVIIIFYCYRVHRQQKLS-- Q8BRS2_MOUSE Q8BRS2_MOUSE -----------EYTTSSPDLLLVIIQVTGVSLLPPLGIAIAVIIIFYCYRVHRQQKLS-- Q543C0_MOUSE Q543C0_MOUSE -----------EYTTSSPDLLLVIIQVTGVSLLPPLGIAIAVIIIFYCYRVHRQQKLS-- TGFR2_MOUSE TGFR2_MOUSE -----------EYTTSSPDLLLVIIQVTGVSLLPPLGIAIAVIIIFYCYRVHRQQKLS-- Q8BQS9_MOUSE Q8BQS9_MOUSE -----------EYTTSSPDLLLVIIQVTGVSLLPPLGIAIAVIIIFYCYRVHRQQKLS-- MATCH CONSENSUS ??????????????????????????V???SL?P?L?????????FY?YR??????????

Q8WNY4_SHEEP Q8WNY4_SHEEP ------------------------------------------------------------ Q9CVP4_MOUSE Q9CVP4_MOUSE ------------------------------------------------------------ Q9DE31_XENLA Q9DE31_XENLA --HSW----PDKRGHCPEELIEARRTDEY---NCRLSSVLISNSPSDMSPMCANSINHN- Q4RE84_TETNG Q4RE84_TETNG GRPDW----------PP------KRSTELYLASDLPCGAVPGGEGG-----CAGDVTGSG B0S5M2_DANRE B0S5M2_DANRE --KEWGPRRTHYQSLDP--AEGQANGIDF---SAK-RPSLSDDINSEMSSTCANNLNHN- Q4SUT7_TETNG Q4SUT7_TETNG --QEW------ERGIKK--RKPKSGGLDC---SDV-CVIMMDDDGSDSSSTLANNLNHN- Q58EQ1_DANRE Q58EQ1_DANRE ---EW------ETK-KPSKHKGPKGALDC---SDA-CAIMMDDDRSDSSSTHANNINHN- Q7ZZU8_DANRE Q7ZZU8_DANRE ---EW------ETK-KPSKHKGPKGPLDC---SDA-CAIMMDDDRSDSSSTHANNINHN- B5X3B3_SALSA B5X3B3_SALSA -------------------VKRKKTPLDF---SDA-HAIMMDDDGSDSSSTHANNLNHN- B2RFG8_SPAAU B2RFG8_SPAAU ------------------------------------------------------------ Q4S0V9_TETNG Q4S0V9_TETNG --TRY----------KK------GPLLDF---SDH-RAIMIDDEGSDSSSTHANNLNHN- TGFR2_CHICK TGFR2_CHICK --KAW------EKNVKP------KKHKDC---SDV-CAIMLDDDHSDISSTCANNINHN- TGFR2_PIG TGFR2_PIG --PSW------DSG-KP------RKLMEF---SEH-LAIILEDDRSDISSTCANNINHN- A3QNQ0_HUMAN A3QNQ0_HUMAN --STW------ETG-KT------RKLMEF---SEH-CAIILEDDRSDISSTCANNINHN- TGFR2_HUMAN TGFR2_HUMAN --STW------ETG-KT------RKLMEF---SEH-CAIILEDDRSDISSTCANNINHN- B4DTV5_HUMAN B4DTV5_HUMAN --STW------ETG-KT------RKLMEF---SEH-CAIILEDDRSDISSTCANNINHN- B4E2S6_HUMAN B4E2S6_HUMAN --STW------ETG-KT------RKLMEF---SEH-CAIILEDDRSDISSTCANNINHN- TGFR2_RAT TGFR2_RAT --PSW------ESS-KP------RKLMDF---SDN-CAIILEDDRSDISSTCANNINHN- Q91ZR8_MOUSE Q91ZR8_MOUSE --PSW------ESS-KP------RKLMDF---SDN-CAIILEDDRSDISSTCANNINHN- Q3UG22_MOUSE Q3UG22_MOUSE --PSW------ESS-KP------RKLMDF---SDN-CAIILEDDRSDISSTCANNINHN- Q8BRS2_MOUSE Q8BRS2_MOUSE --PSW------ESS-KP------RKLMDF---SDN-CAIILEDDRSDISSTCANNINHK- Q543C0_MOUSE Q543C0_MOUSE --PSW------ESS-KP------RKLMDF---SDN-CAIILEDDRSDISSTCANNINHN- TGFR2_MOUSE TGFR2_MOUSE --PSW------ESS-KP------RKLMDF---SDN-CAIILEDDRSDISSTCANNINHN- Q8BQS9_MOUSE Q8BQS9_MOUSE --PSW------ESS-KP------RKLMDF---SDN-CAIILEDDRSDISSTCANNINHN- MATCH CONSENSUS ????????????????????????????????S????????????S??S???AN??NH??

Q8WNY4_SHEEP Q8WNY4_SHEEP ------------------------------------------------------------ Q9CVP4_MOUSE Q9CVP4_MOUSE --------------------------------------F--------------------- Q9DE31_XENLA Q9DE31_XENLA --TELLPIELDQRVGKGRFAKVWRAKLRHSAP---GH-YEMVAVKIFPCQEFSSWKNESR Q4RE84_TETNG Q4RE84_TETNG EVTELLPIKLEVLVGKGRFAEVWLGRLLQAEKAEGTV-HDPVAVKVFPAVEYESWRNECS B0S5M2_DANRE B0S5M2_DANRE --TEQLPIQLEALVGKGRFAEVWRARLSHNES---GQ-YETVAVKIFPAVEYSSWCNERA Q4SUT7_TETNG Q4SUT7_TETNG --TEPLPIELDQLVGKGRFAQVFKAKLKQNAS---DQ-FETVAVKIFPYEEYASWKNEKD Q58EQ1_DANRE Q58EQ1_DANRE --MDPLPIELDLQVGKGRFAEVYKAKLRQSPS---EQ-FETVAVKIFPYEEYASWKNEKD Q7ZZU8_DANRE Q7ZZU8_DANRE --MDPLPIELDLQVGKGRFAEVYKAKLRQSPS---EQ-FETVAVKIFPYEEYASWKNEKD B5X3B3_SALSA B5X3B3_SALSA --TELLPIELDAQVGKGRFAEVYKAKLKQGATGAGEH-FETVAVKIFADEEYASWKNEKD B2RFG8_SPAAU B2RFG8_SPAAU -----------------------GTRLKQGSSVSEEQGFETVAIKIFTYEEYASWKNEKE Q4S0V9_TETNG Q4S0V9_TETNG --TELLPIDLDVQVGKGRFAEVYKAKLKQGSSVSEEQGFETVAIKIFPYTEYASWKIEKE TGFR2_CHICK TGFR2_CHICK --TELLPIELDIVVGKGRFAEVYKAKLKQNTS---EQ-YETVAVKIFPYEEYASWKTEKD TGFR2_PIG TGFR2_PIG --TELLPIELDTLVGKGRFAEVYKAKLRQNTS---EQ-FETVAVKIFPYEEYASWKTEKD A3QNQ0_HUMAN A3QNQ0_HUMAN --TELLPIELDTLVGKGRFAEVYKAKLKQNTS---EQ-FETVAVKIFPYEEYASWKTEKD TGFR2_HUMAN TGFR2_HUMAN --TELLPIELDTLVGKGRFAEVYKAKLKQNTS---EQ-FETVAVKIFPYEEYASWKTEKD B4DTV5_HUMAN B4DTV5_HUMAN --TELLPIELDTLVGKGRFAEVYKAKLKQNTS---EQ-FETVAVKIFPYEEYASWKTEKD B4E2S6_HUMAN B4E2S6_HUMAN --TELLPIELDTLVGKGRFAEVYKAKLK-------------------------------- TGFR2_RAT TGFR2_RAT --TELLPIELDTLVGKGRFAEVYKAKLKQNTS---EQ-FETVAVKIFPYEEYSSWKTEKD Q91ZR8_MOUSE Q91ZR8_MOUSE --TELLPIELDTLVGKGRFAEVYKAKLKQNTS---EQ-FETVAVKIFPYEEYSSWKTEKD Q3UG22_MOUSE Q3UG22_MOUSE --TELLPIELDTLVGKGRFAEVYKAKLKQNTS---EQ-FETVAVKIFPYEEYSSWKTEKD Q8BRS2_MOUSE Q8BRS2_MOUSE --TELLPIELDTLVGKGRFAEVYKAKLKQNTS---EQ-FETVAVKIFPYEEYSSWKTEKD Q543C0_MOUSE Q543C0_MOUSE --TELLPIELDTLVGKGRFAEVYKAKLKQNTS---EQ-FETVAVKIFPYEEYSSWKTEKD TGFR2_MOUSE TGFR2_MOUSE --TELLPIELDTLVGKGRFAEVYKAKLKQNTS---EQ-FETVAVKIFPYEEYSSWKTEKD Q8BQS9_MOUSE Q8BQS9_MOUSE --TELLPIELDTLVGKGRFAEVYKAKLKQNTS---EQ-FETVAVKIFPYEEYSSWKTEKD MATCH CONSENSUS ?????LPI?L???VGKGRFA?V??A?L????????????E?VA?KIF???EY?SW??E??

Q8WNY4_SHEEP Q8WNY4_SHEEP -----MLRHENILGFIASDMT---SRHSSTQLWLITHYHEMGSLYDYLQLTTLDTVSCLR Q9CVP4_MOUSE Q9CVP4_MOUSE ---------------------------------------------DYLNRYTVTVEGMIK Q9DE31_XENLA Q9DE31_XENLA IFADANLKHKNVLQFITTEIR---GTSLQKEYWIITTYHAKGNLKDYQASHFLNWTTFLK Q4RE84_TETNG Q4RE84_TETNG ILSDPKMEHGNIVRFLAAEDR-GPPGHALRQYWLVLAYHSLGNLQDFLAANLLSWDELVA B0S5M2_DANRE B0S5M2_DANRE IFSDANLKHENVVQFLTAEERGGTSATSQRQYWLIMAYYNMGNLQDFLVGNILTWAELCS Q4SUT7_TETNG Q4SUT7_TETNG IFSNSDLRHENILHFLTAEEK-----KAQRQYWLITAFHARGNLQEYLTHNVISWEELKI Q58EQ1_DANRE Q58EQ1_DANRE IFQDIDLKHENILHFLTAEER-----KVEKQYWLITAFHPRGNLQEYLMRHLLSWEDLRL Q7ZZU8_DANRE Q7ZZU8_DANRE IFQDIDLKHENILHFLTAEER-----KVEKQYWLITAFHPRGNLQEYLMRHLLSWEDLRL B5X3B3_SALSA B5X3B3_SALSA IFSDADLRHENVLHFLTAEDH-----KVEKQYWLITAYHPRGNLQEYLTRHVISWDDLWV B2RFG8_SPAAU B2RFG8_SPAAU IFSDADLRHENVLHFLTAEER-----KVQRQYWLITAYHPRGNLQEYLIHHIVSWHDLWM Q4S0V9_TETNG Q4S0V9_TETNG IFSDADLKHDNVLHFLTAEER-----KMQRQYWLITAYHPAGNLQEYLIQHVINWHELWM TGFR2_CHICK TGFR2_CHICK IFSDVNLKHENILQFLTAEER---KTDLGKQYWLITAFHARGNLQEYLTRHIISWEDLWK TGFR2_PIG TGFR2_PIG IFSDL------------------------------------------------------- A3QNQ0_HUMAN A3QNQ0_HUMAN IFSDINLKHENILQFLTAEER---KTELGKQYWLITAFHAKGNLQEYLTRHVISWEDLRK TGFR2_HUMAN TGFR2_HUMAN IFSDINLKHENILQFLTAEER---KTELGKQYWLITAFHAKGNLQEYLTRHVISWEDLRK B4DTV5_HUMAN B4DTV5_HUMAN IFSDINLKHENILQFLTAEER---KTELGKQYWLITAFHAKGNLQEYLTRHVISWEDLRK B4E2S6_HUMAN B4E2S6_HUMAN --------HENILQFLTAEER---KTELGKQYWLITAFHAKGNLQEYLTRHVISWEDLRK TGFR2_RAT TGFR2_RAT IFSDINLKHENILQFLTAEER---KTEMGKQYWLITAFHAKGNLQEYLTRHVISWEDLRK Q91ZR8_MOUSE Q91ZR8_MOUSE IFSDINLKHENILQFLTAEER---KTELGKQYWLITAFHAKGNLQEYLTRHVISWEDLRK Q3UG22_MOUSE Q3UG22_MOUSE IFSDINLKHENILQFLTAEER---KTELGKQYWLITAFHAKGNLQEYLTRHVISWEDLRK Q8BRS2_MOUSE Q8BRS2_MOUSE IFSDINLKHENILQFLTAEER---KTELGKQYWLITAFHAKGNLQEYLTRHVISWEDLRK Q543C0_MOUSE Q543C0_MOUSE IFSDINLKHENILQFLTAEER---KTELGKQYWLITAFHAKGNLQEYLTRHVISWEDLRK TGFR2_MOUSE TGFR2_MOUSE IFSDINLKHENILQFLTAEER---KTELGKQYWLITAFHAKGNLQEYLTRHVISWEDLRK Q8BQS9_MOUSE Q8BQS9_MOUSE IFSDINLKHENILQFLTAEER---KTELGKQYWLITAFHAKGNLQEYLTRHVISWEDLRK MATCH CONSENSUS IF?D??L?H?N?L?FLTAE???????????QYWLITA?H??GNLQ?YL??????W??L??

Q8WNY4_SHEEP Q8WNY4_SHEEP IVLSIASGLAHLHIEIFGTQGKPA-----IAHRDLKSKNILVKKNGQCCIADLGLAVMHS Q9CVP4_MOUSE Q9CVP4_MOUSE LALSTASGLAHLHMEIVGTQGKPA-----IAHRDLKSKNILVKKNGTCCIADLGLAVRHD Q9DE31_XENLA Q9DE31_XENLA MAGSIVNGVAHLHSDCTPC-GAMK---IPIAHRDIKSTNILVKSDCECVVCDFGIAVRLD Q4RE84_TETNG Q4RE84_TETNG MAGSIAKGLAHLHSDTTPG-GLPK---VPVAHRDLKSSNIVMKSRSECALCDFGLALRLD B0S5M2_DANRE B0S5M2_DANRE LAGSVARGLAHLHSDTTPC-GIQK---VPIAHRDLKSSNIVLKNQSECVLCDFGLALRLD Q4SUT7_TETNG Q4SUT7_TETNG LGSSLAQGVSHLHSDRLPC-GRPKVERVAIVHRDLKSSNILVKSDLTCCLCDFGLGLQLD Q58EQ1_DANRE Q58EQ1_DANRE LGSSLASGVAHLHSDHTPC-GRPK---VPIVHRDLKSSNILVKNDLTCCLCDFGLGLRLD Q7ZZU8_DANRE Q7ZZU8_DANRE LGSSLASGVAHLHSDHTPC-GRPK---VPIVHRDLKSSNILVKNDLTCCLCDFGLGLRLD B5X3B3_SALSA B5X3B3_SALSA LGGSLARGVAHLHSDHTLC-GRYK---VPIVHRDIKSSNILVKGDLTCVLCDFGLGLRLD B2RFG8_SPAAU B2RFG8_SPAAU LGGSLSRGVAHLHSDHTTC-GRYK---VPIAHRDIKSSNILVKNDLTCVLCDFGLALRLD Q4S0V9_TETNG Q4S0V9_TETNG LGSTLACGVAHLHSDHTGC-GRYK---VPVAHRDIKSSNILVKNDLTCCLCDFGLALRLD TGFR2_CHICK TGFR2_CHICK LGGSLARGIAHLHSDHTPC-GRPK---TPIVHRDLKSSNILVKNDLTCCLCDFGLSLRLD TGFR2_PIG TGFR2_PIG ------------------------------------------------------------ A3QNQ0_HUMAN A3QNQ0_HUMAN LGSSLARGIAHLHSDHTPC-GRPK---MPIVHRDLKSSNILVKNDLTCCLCDFGLSLRLD TGFR2_HUMAN TGFR2_HUMAN LGSSLARGIAHLHSDHTPC-GRPK---MPIVHRDLKSSNILVKNDLTCCLCDFGLSLRLD B4DTV5_HUMAN B4DTV5_HUMAN LGSSLARGIAHLHSDHTPC-GRPK---MPIVHRDLKSSNILVKNDLTCCLCDFGLSLRLD B4E2S6_HUMAN B4E2S6_HUMAN LGSSLARGIAHLHSAHTPC-GRPK---MPIVHRDLKSSNILVKNDLTCCLCDFGLSLRLD TGFR2_RAT TGFR2_RAT LGSSLARGIAHLHSDHTPC-GRPK---MPIVHRDLKSSNILVKNDLTCCLCDFGLSLRLD Q91ZR8_MOUSE Q91ZR8_MOUSE LGSSLARGIAHLHSDHTPC-GRPK---MPIVHRDLKSSNILVKNDLTCCLCDFGLSLRLD Q3UG22_MOUSE Q3UG22_MOUSE LGSSLARGIAHLHSDHTPC-GRPK---MPIVHRDLKSSNILVKNDLTCCLCDFGLSLRLD Q8BRS2_MOUSE Q8BRS2_MOUSE LGSSLARGIAHLHSDHTPC-GRPK---MPIVHRDLKSSNILVKNDLTCCLCDFGLSLRLD Q543C0_MOUSE Q543C0_MOUSE LGSSLARGIAHLHSDHTPC-GRPK---MPIVHRDLKSSNILVKNDLTCCLCDFGLSLRLD TGFR2_MOUSE TGFR2_MOUSE LGSSLARGIAHLHSDHTPC-GRPK---MPIVHRDLKSSNILVKNDLTCCLCDFGLSLRLD Q8BQS9_MOUSE Q8BQS9_MOUSE LGSSLARGIAHLHSDHTPC-GRPK---MPIVHRDLKSSNILVKNDLTCCLCDFGLSLRLD MATCH CONSENSUS L??S?A?G?AHLHSD?T?C?G??K????PI?HRD?KSSNILVK????C?LCDFGL?LRLD

Q8WNY4_SHEEP Q8WNY4_SHEEP QSTNQLDVGNNPRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEV---ARRMV Q9CVP4_MOUSE Q9CVP4_MOUSE SATDTIDIAPNHRVGTKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEI---ARRCS Q9DE31_XENLA Q9DE31_XENLA LSLTTEDFANSGQVGTARYMAPEVLESRVNLEDLESFKQMDVYSLSLVLWEL---ATRCD Q4RE84_TETNG Q4RE84_TETNG LSLTVDDYANSGQVGTARYMAPEVLESRVNLEDLEAFKQMDVYSMALVLWEM---ASRCR B0S5M2_DANRE B0S5M2_DANRE LSLTVDDFANSGQVGTARYMAPEVLESRVNLEDLESFKQIDIYSMALVMWEM---VSRCD Q4SUT7_TETNG Q4SUT7_TETNG SSLSVDDLANSGQVGTARYMAPEVLEARLNLENTESFKQADIYSMALVLWESDIEVRRCR Q58EQ1_DANRE Q58EQ1_DANRE NSLSVDELANSGQVGTARYMAPEVLESRINLENIESFKQTDVYSMALVLWEI---TSRCN Q7ZZU8_DANRE Q7ZZU8_DANRE DSLSVDELANSGQVGTARYMAPEVLESRINLENIESFKQTDVYSMALVLWEI---TSRCN B5X3B3_SALSA B5X3B3_SALSA NSLSVDELANSGQVGTARYMAPEVLESRINLENIESFKQTDVYSMALVLWEI---TSRCN B2RFG8_SPAAU B2RFG8_SPAAU NSLSVDELANSGQVGTARYMAPEVLESRINLENIESFKQADVYSMALVLWEI-------- Q4S0V9_TETNG Q4S0V9_TETNG NSLSVDELANSGQVGTARYMAPEVLESRINLENIESFKQADVYSMALVLWEI---TSRCN TGFR2_CHICK TGFR2_CHICK PSLSVDDLANSGQVGTARYMAPEVLESRMNLENMESFKQTDVYSMALVLWEM---TSRCN TGFR2_PIG TGFR2_PIG ------------------------------------------------------------ A3QNQ0_HUMAN A3QNQ0_HUMAN PTLSVDDLANSGQVGTARYMAPEVLESRMNLENVESFKQTDVYSMALVLWEM---TSRCN TGFR2_HUMAN TGFR2_HUMAN PTLSVDDLANSGQVGTARYMAPEVLESRMNLENVESFKQTDVYSMALVLWEM---TSRCN B4DTV5_HUMAN B4DTV5_HUMAN PTLSVDDLANSGQVGTARYMAPEVLESRMNLENVESFKQTDVYSMALVLWEM---TSRCN B4E2S6_HUMAN B4E2S6_HUMAN PTLSVDDLANSGQVGTARYMAPEVLESRMNLENVESFKQTDVYSMALVLWEM---TSRCN TGFR2_RAT TGFR2_RAT PTLSVDDLANSGQVGTARYMAPEVLESRMNLENMESFKQTDVYSMALVLWEM---TSRCN Q91ZR8_MOUSE Q91ZR8_MOUSE PTLSVDDLANSGQVGTARYMAPEVLESRMNLENVESFKQTDVYSMALVLWEM---TSRCN Q3UG22_MOUSE Q3UG22_MOUSE PTLSVDDLANSGQVGTARYMAPEVLESRMNLENVESFKQTDVYSMALVLWEM---TSRCN Q8BRS2_MOUSE Q8BRS2_MOUSE PTLSVDDLANSGQVGTARYMAPEVLESRMNLENVESFKQTDVYSMALVLWEM---TSRCN Q543C0_MOUSE Q543C0_MOUSE PTLSVDDLANSGQVGTARYMAPEVLESRMNLENVESFKQTDVYSMALVLWEM---TSRCN TGFR2_MOUSE TGFR2_MOUSE PTLSVDDLANSGQVGTARYMAPEVLESRMNLENVESFKQTDVYSMALVLWEM---TSRCN Q8BQS9_MOUSE Q8BQS9_MOUSE PTLSVDDLANSGQVGTARYMAPEVLESRMNLENVESFKQTDVYSMALVLWEM---TSRCN MATCH CONSENSUS ??L?VD??ANSGQVGTARYMAPEVLESR?NLE??ESFKQ?D?YSMALVLWE??????RC?

Q8WNY4_SHEEP Q8WNY4_SHEEP SNGIVEDYKPPFYDVVPNDPSFEDMRKVVCVDQQRPN----------------------- Q9CVP4_MOUSE Q9CVP4_MOUSE IGGIHEDYQLPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWY Q9DE31_XENLA Q9DE31_XENLA ASGEVRSYELPFGSKVREQPCVETMRDLVLHGRVRPEIPDTWRRHPGLDVLCDTITECWD Q4RE84_TETNG Q4RE84_TETNG ANGEVRSYEPAFGSQVCEQPCVDSMRDLVLRDRGRPDIPATWSRHKGLSIFCSTIMECWD B0S5M2_DANRE B0S5M2_DANRE VIGEVKSYEPPFGSKVCEQPCVDSMRDLVLRDRGRPDIPDSWTTHSGMQLLCATITECWD Q4SUT7_TETNG Q4SUT7_TETNG RGEGLRACLRLQGARA---PCVESMKDNVLRDRRRPEIPDTWLRRQGVAMMCGTIMECWD Q58EQ1_DANRE Q58EQ1_DANRE AIGEVKDYEPPFGSKVREHPCVESMKDNVLRDRGRPEIPSSWMKHQGVAAVCATINECWD Q7ZZU8_DANRE Q7ZZU8_DANRE AIGEVKDYEPPFGSKVREHPCVESMKDNVLRDRGRPEIPSSWMKHQGVAAVCATINECWD B5X3B3_SALSA B5X3B3_SALSA AIGEVKDYEPPFG-KVREHPCVESMKDSVLRDRGRPEIPNSWINHPGIQVVCGTIDECWD B2RFG8_SPAAU B2RFG8_SPAAU ------------------------------------------------------------ Q4S0V9_TETNG Q4S0V9_TETNG AIGEVKEYEPPFG-NVRENPCVESMKDSVLRDRGRPELPNSWINHSGIQMVCAAIEECWD TGFR2_CHICK TGFR2_CHICK GVGEVKEYEPPFGSKVREHPCVESMKDNVLRDRGRPEIPSSWLNHQGIQMVCETLIECWD TGFR2_PIG TGFR2_PIG ------------------------------------------------------------ A3QNQ0_HUMAN A3QNQ0_HUMAN AVGEVKDYEPPFGSKVREHPCVESMKDNVLRDRGRPEIPSFWLNHQGIQMVCETLTECWD TGFR2_HUMAN TGFR2_HUMAN AVGEVKDYEPPFGSKVREHPCVESMKDNVLRDRGRPEIPSFWLNHQGIQMVCETLTECWD B4DTV5_HUMAN B4DTV5_HUMAN AVGEVKDYEPPFGSKVREHPCVESMKDNVLRDRGRPEIPSFWLNHQGIQMVCETLTECWD B4E2S6_HUMAN B4E2S6_HUMAN AVGEVKDYEPPFGSKVREHPCVESMKDNVLRDRGRPEIPSFWLNHQGIQMVCETLTECWD TGFR2_RAT TGFR2_RAT AVGEVKDYEPPFGSKVREHPCVESMKDNVLRDRGRPEIPSFWLNHQGIQIVCETLTECWD Q91ZR8_MOUSE Q91ZR8_MOUSE AVGEVKDYEPPFGSKVREHPCVESMKDSVLRDRGRPEIPSFWLNHQGIQIVCETLTECWD Q3UG22_MOUSE Q3UG22_MOUSE AVGEVKDYEPPFGSKVREHPCVESMKDSVLRDRGRPEIPSFWLNHQGIQIVCETLTECWD Q8BRS2_MOUSE Q8BRS2_MOUSE AVGEVKDYEPPFGSKVREHPCVESMKDSVLRDRGRPEIPSFWLNHQGIQIVCETLTECWD Q543C0_MOUSE Q543C0_MOUSE AVGEVKDYEPPFGSKVREHPCVESMKDSVLRDRGRPEIPSFWLNHQGIQIVCETLTECWD TGFR2_MOUSE TGFR2_MOUSE AVGEVKDYEPPFGSKVREHPCVESMKDSVLRDRGRPEIPSFWLNHQGIQIVCETLTECWD Q8BQS9_MOUSE Q8BQS9_MOUSE AVGEVKDYEPPFGSKVREHPCVESMKDSVLRDRGRPEIPSFWLNHQGIQIVCETLTECWD MATCH CONSENSUS ??G?V??Y??PFG??V???PCVE?M?D?VL?DR?RP?IP??W????G????C????ECWD

Q8WNY4_SHEEP Q8WNY4_SHEEP -------------------------------------------------- Q9CVP4_MOUSE Q9CVP4_MOUSE ANGAARLTALRIKKTLSQL-SQQEGIKM---------------------- Q9DE31_XENLA Q9DE31_XENLA HDPEARLTVHCVAERFKLMPQMECDAMNHHSSG----------------- Q4RE84_TETNG Q4RE84_TETNG HDPEARLTAHCVVERFTALQ------------------------------ B0S5M2_DANRE B0S5M2_DANRE HDPEARLTAHCVVERFNTL--AQEELENSICT------------------ Q4SUT7_TETNG Q4SUT7_TETNG HDPEARLTAHCVAKRISEMEDELDKLSSHSSSTEKIPEEL---------- Q58EQ1_DANRE Q58EQ1_DANRE HDPEARLTAQCVAERFNEMDDDLDKLSTCSSSEEKIPEDCAVSVSDDK-- Q7ZZU8_DANRE Q7ZZU8_DANRE HDPEARLTAQCVAERFNEMDDDLDKLSTCSSSEEKIPEDCAVSVSDDK-- B5X3B3_SALSA B5X3B3_SALSA HDPEARLTAQCVAERFNDM-EHPDKLSVRSNSEEKIPQDVSATEIEEIEK B2RFG8_SPAAU B2RFG8_SPAAU -------------------------------------------------- Q4S0V9_TETNG Q4S0V9_TETNG HDPEARLTAQCVAERFYDM-EYLDKLSARSDSEEKIPEQ----------- TGFR2_CHICK TGFR2_CHICK HDPEARLTAQCVAERFSEF-KHHDKLSGRSCSEEKIPEDGSVTTAK---- TGFR2_PIG TGFR2_PIG -------------------------------------------------- A3QNQ0_HUMAN A3QNQ0_HUMAN HDPEARLTAQCVAERFSEL-EHLDRLSGRSCSEEKIPEDGSLNTTK---- TGFR2_HUMAN TGFR2_HUMAN HDPEARLTAQCVAERFSEL-EHLDRLSGRSCSEEKIPEDGSLNTTK---- B4DTV5_HUMAN B4DTV5_HUMAN HDPEARLTAQCVAERFSEL-EHLDRLSGRSCSEEKIPEDGSLNTTK---- B4E2S6_HUMAN B4E2S6_HUMAN HDPEARLTAQCVAERFSEL-EHLDRLSGRSCSEEKIPEDGSLNTTK---- TGFR2_RAT TGFR2_RAT HDPEARLTAQCVAERFSEL-EHPDRLSGRSCSQEKIPEDGSLNTTK---- Q91ZR8_MOUSE Q91ZR8_MOUSE HDPEARLTAQCVAERFSEL-EHPERLSGRSCSQEKIPEDGSLNTTK---- Q3UG22_MOUSE Q3UG22_MOUSE HDPEARLTAQCVAERFSEL-EHPERLSGRSCSQEKIPGDGSLNTTK---- Q8BRS2_MOUSE Q8BRS2_MOUSE HDPEARLTAQCVAERFSEL-EHPERLSGRSCSQEKIPEDGSLNTTK---- Q543C0_MOUSE Q543C0_MOUSE HDPEARLTAQCVAERFSEL-EHPERLSGRSCSQEKIPEDGSLNTTK---- TGFR2_MOUSE TGFR2_MOUSE HDPEARLTAQCVAERFSEL-EHPERLSGRSCSQEKIPEDGSLNTTK---- Q8BQS9_MOUSE Q8BQS9_MOUSE HDPEARLTAQCVAERFSEL-EHPERLSGRSCSQEKIPEDGSLNTTK---- MATCH CONSENSUS HDPEARLTA?CV??R???????????????????????????????????


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