Alignment of the gene Family HBG106193 of HOVERGEN

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Threshold: 50% 80% 100%
Size: Bigger Smaller Normal
Isoforms are ON
Q9BLG2_HALRO Q9BLG2_HALRO TRA----EELPDIASAKEFYEKYEPKEILGVGVSSTVRRCINRNTRQEYAVKIIDIIGND A0JME5_DANRE A0JME5_DANRE TKE----DEIPDWAGAQDFYQKYDPKEILGRGVSSVVRRCIHKRTTQEYAVKVIDITPSD Q503G9_DANRE Q503G9_DANRE TKE----EENPEWVGGQEFYDKYDPKEILGRGVSSVVRRCVDKRTGQEYAVKIIDITLSD Q6DJ64_XENTR Q6DJ64_XENTR TKD----EELPDWQTSQEFYEKYEPKEILGRGVSSVVRRCIFKPSREDFAVKIIDITG-D Q7ZTP8_XENLA Q7ZTP8_XENLA TRE----EELPDWQTSQDFYEKYEPKEILGRGVSSVVRRCIFKPTREDFAVKIIDITG-D Q5ZJ45_CHICK Q5ZJ45_CHICK TKE----EDLPDWNTSKEFYEKYEPKEVLGRGVSSVVRRCIHKATRQEYAVKIIDITA-G B7Z5U3_HUMAN B7Z5U3_HUMAN -----------------MHPQAHEPG----------VRREGHRR----HRWRQLQPGGGA Q29RI2_BOVIN Q29RI2_BOVIN TQD----KSLPDSSSAQSFYENYEPKEILGRGVSSVVRRCIHKPTCQEYAVKIIDITGGG PHKG1_MOUSE PHKG1_MOUSE TRD----DALPDSHSAQTFYENYEPKEILGRGVSSVVRRCIHKPTCQEYAVKIIDITGGG PHKG1_RAT PHKG1_RAT TRD----EALPDSHSAQNFYENYEPKEILGRGVSSVVRRCIHKPTCQEYAVKIIDITGGG PHKG1_RABIT PHKG1_RABIT TRD----AALPGSHSTHGFYENYEPKEILGRGVSSVVRRCIHKPTCKEYAVKIIDVTGGG Q6NSZ4_HUMAN Q6NSZ4_HUMAN TRD----EALPDSHSAQDFYENYEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGG B7Z6U2_HUMAN B7Z6U2_HUMAN TRD----EALPDSHSAQDFYENYEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGG B2R757_HUMAN B2R757_HUMAN TRD----EALPDSHSAQDFYENYEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGG B7Z1D0_HUMAN B7Z1D0_HUMAN TRD----EALPDSHSAQDFYENYEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGG PHKG1_HUMAN PHKG1_HUMAN TRD----EALPDSHSAQDFYENYEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGG Q75LP5_HUMAN Q75LP5_HUMAN TRD----EALPDSHSAQDFYENYEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGG Q5HZR1_XENLA Q5HZR1_XENLA TRDAEARDELPDWAGAKEFYQKYDPKEIIGRGVSSTVRRCIHRETGRQFAVKIIEVTP-E PHKG2_RAT PHKG2_RAT TLDVGPEDELPDWAAAKEFYQKYDPKDIIGRGVSSVVRRCVHRATGDEFAVKIMEVSA-E A6H632_MOUSE A6H632_MOUSE TLDVGPEDELPDWAAAKEFYQKYDPKDIIGRGVSSVVRRCVHRATGDEFAVKIMEVSA-E PHKG2_MOUSE PHKG2_MOUSE TLDVGPEDELPDWAAAKEFYQKYDPKDIIGRGVSSVVRRCVHRATGDEFAVKIMEVSA-E B7U172_SHEEP B7U172_SHEEP TLDVGPEDELPDWAAAKEFYQKYDPKDVIGRGVSSVVRRCVHRATGQEFAVKIMEVTA-E PHKG2_BOVIN PHKG2_BOVIN TLDVGPEDELPDWAAAKEFYQKYDPKDVIGRGVSSVVRRCVHRATGQEFAVKIMEVTA-E B4DEB7_HUMAN B4DEB7_HUMAN TLDVGPEDELPDWAAAKEFYQKYDPKDVIGRGVSSVVRRCVHRATGHEFAVKIMEVTA-E A8K0C7_HUMAN A8K0C7_HUMAN TLDVGPEDELPDWAAAKEFYQKYDPKDVIGRGVSSVVRRCVHRATGHEFAVKIMEVTA-E PHKG2_HUMAN PHKG2_HUMAN TLDVGPEDELPDWAAAKEFYQKYDPKDVIGRGVSSVVRRCVHRATGHEFAVKIMEVTA-E Q59GQ4_HUMAN Q59GQ4_HUMAN ------------------------------------------------------------ Q4S4Q5_TETNG Q4S4Q5_TETNG TKDIVVGDELPDWVGAKEFYQKYDPKEVIGRGVSSVVRRCVHRHTGQELAVKIIEITA-E B5X389_SALSA B5X389_SALSA TRDIVIGDELPDWVGAKEFYQKYDPKEVIGRGVSSVVRRCVHKHTGQELAVKIIEITA-E A7YYF0_DANRE A7YYF0_DANRE TRDIVLGDELPDWVGAKEFYQKYDPKEVIGRGVSSVVRRCVHKHTGQEFAVKIIEITA-E B1H2F1_XENTR B1H2F1_XENTR TRDIVLGDELPDWVGAKEFYQKYDPKEVIGRGVSSVVRRCVHKHTGQEFAVKIIEITA-E Q6DI11_DANRE Q6DI11_DANRE TRDIVLGDELPDWVGAKEFYQKYDPKEVIGRGVSSVVRRCVHKHTGQEFAVKIIEITA-E Q7ZYW8_DANRE Q7ZYW8_DANRE TRDIVLGDELPDWVGAKEFYQKYDPKEVIGRGVSSVVRRCVHKHTGQEFAVKIIEITA-E MATCH CONSENSUS T????????LPD??????FY??Y?PK???GRGVSSVVRRC?H??T??E?AVK????T???

Q9BLG2_HALRO Q9BLG2_HALRO DILAEDLVNV---THNEINILRRVSSRAHIIELVDVFETSTFFFLIFEI----------- A0JME5_DANRE A0JME5_DANRE KMNTEEIEEIRNATIKEIDILKKVCGQENIIQLKDCFETKAFFFLVFDL----------- Q503G9_DANRE Q503G9_DANRE KMTPQEIQEIQQATVKEIDILRKVSGQKNIIQLKDCFESKAFFFLVFDL----------- Q6DJ64_XENTR Q6DJ64_XENTR HLSSEQIAELRDSTVKEIDILKKVSGFPNVIQLKDSYESHTFFFLVFDL----------- Q7ZTP8_XENLA Q7ZTP8_XENLA HLTSEQIAELRESTIKEIDILNKVSGFSNVIQLKDSYESHTFFFLVFDL----------- Q5ZJ45_CHICK Q5ZJ45_CHICK NISPQEVQELREATAKEIDILRKVSGHPNVIQLKDSYESSTFFFLVFDL----------- B7Z5U3_HUMAN B7Z5U3_HUMAN GAARSHAEG---------------GGHPAQGLRAPQHQ---------------------- Q29RI2_BOVIN Q29RI2_BOVIN SFSSEEVQELREATQKEVDILRKVSGHPNIIQLKDTYETNTFFFLVFDL----------- PHKG1_MOUSE PHKG1_MOUSE SFSSEEVQELREATLKEVDILQKVSGHPNIIQLKDTYETNTFFFLVFDL----------- PHKG1_RAT PHKG1_RAT SFSSEEVQELREATLKEVDILQKVSGHPNIIQLKDTYETNTFFFLVFDL----------- PHKG1_RABIT PHKG1_RABIT SFSAEEVQELREATLKEVDILRKVSGHPNIIQLKDTYETNTFFFLVFDL----------- Q6NSZ4_HUMAN Q6NSZ4_HUMAN SFSPEEVRELREATLKEVDILRKVSGHPNIIQLKDTYETNTFFFLVFDLFH--------- B7Z6U2_HUMAN B7Z6U2_HUMAN SFSPEEVRELREATLKEVDILRK---------LKDTYETNTFFFLVFDL----------- B2R757_HUMAN B2R757_HUMAN SFSPEEVRELREATLKEVDILRKVSGHPNIIQLKDTYETNTFFFLVFDL----------- B7Z1D0_HUMAN B7Z1D0_HUMAN SFSPEEVRELREATLKEVDILRKVSGHPNIIQLKDTYETNTFLFLVFDLWEDTDTMEMEQ PHKG1_HUMAN PHKG1_HUMAN SFSPEEVRELREATLKEVDILRKVSGHPNIIQLKDTYETNTFFFLVFDL----------- Q75LP5_HUMAN Q75LP5_HUMAN SFSPEEVRELREATLKEVDILRKVSGHPNIIQLKDTYETNTFFFLVFDL----------- Q5HZR1_XENLA Q5HZR1_XENLA RLSPEQLKEVRLSTAKEMEILHHVSNHPSIISLIDSYESSTFIFLVFDL----------- PHKG2_RAT PHKG2_RAT RLSLEQLEEVRDATRREMHILRQVAGHPHIITLIDSYESSSFMFLVFDL----------- A6H632_MOUSE A6H632_MOUSE RLSLEQLEEVRDATRREMHILRQVAGHPHIITLIDSYESSSFMFLVFDL----------- PHKG2_MOUSE PHKG2_MOUSE RLSLEQLEEVRDATRREMHILRQVAGHPHIITLIDSYESSSFMFLVFDL----------- B7U172_SHEEP B7U172_SHEEP RLSPEQLEEVREATRRETHILRQVAGHPHIITLIDSYESSSFMFLVFDL----------- PHKG2_BOVIN PHKG2_BOVIN RLSPEQLEEVREATRRETHILRQVAGHPHIITLIDSYESSSFMFLVFDL----------- B4DEB7_HUMAN B4DEB7_HUMAN RLSPEQLEEVREATRRETHILRQVAGHPHIITLIDSYESSSFMFLVFDL----------- A8K0C7_HUMAN A8K0C7_HUMAN RLSPEQLEEVREATRRETHILRQVAGHPHIITLIDSYESSSFMFLVFDL----------- PHKG2_HUMAN PHKG2_HUMAN RLSPEQLEEVREATRRETHILRQVAGHPHIITLIDSYESSSFMFLVFDL----------- Q59GQ4_HUMAN Q59GQ4_HUMAN ------------------------------------------------------------ Q4S4Q5_TETNG Q4S4Q5_TETNG KMTAQQLAEVKTSTLKEIQVLNMVKGHASIITLIDSYESTTFIFLVFDL----------- B5X389_SALSA B5X389_SALSA KMTAQQLEEVKSSTLKEIQVLNMVKGHSSIITLIDSYESTTFIFLVFDL----------- A7YYF0_DANRE A7YYF0_DANRE KMTEQQLEEVKSSTLKEIHVLNLVKGHPSIITLIDSYESTAFIFLVFDL----------- B1H2F1_XENTR B1H2F1_XENTR KMTEQQLEEVKSSTLKEIHVLNLVKGHPSIITLIDSYESTAFIFLVFDL----------- Q6DI11_DANRE Q6DI11_DANRE KMTEQQLEEVKSSTLKGIHVLNLVKGHPSIITLIDSYESTAFIFLVFDL----------- Q7ZYW8_DANRE Q7ZYW8_DANRE KMTEQQLEEVKSSTLKEIHVLNLVKGHPSIITLIDSYESTAFIFLVFDL----------- MATCH CONSENSUS ????????E????T??E???L??V?G???II?L?D?YE???F?FLVFDL???????????

Q9BLG2_HALRO Q9BLG2_HALRO ---------------------LRKGELFDYLTEVVKFSERQTRTTMRDLLEAVLFLHDNK A0JME5_DANRE A0JME5_DANRE ---------------------MKKGELFDYLTEKVTLSEKETRKIMRSLLEVVQFLHSQN Q503G9_DANRE Q503G9_DANRE ---------------------MKRGELFDYLTEKVTLSEKETRKIIRALLEVVEYLHAHN Q6DJ64_XENTR Q6DJ64_XENTR ---------------------MRRGELFDYLTEKVTLSEKETRKIMRSLLEVVSKLHAYN Q7ZTP8_XENLA Q7ZTP8_XENLA ---------------------MRKGELFDYLTEQVTLSEKETRKIIRSLLEVISKLHGYN Q5ZJ45_CHICK Q5ZJ45_CHICK ---------------------MKRGELFDYLTEKVTLSEKETRKIMHALLEVIEYLHSID B7Z5U3_HUMAN B7Z5U3_HUMAN ---------------------MKRGELFDYLTEKVTLSEKETRKIMRALLEVICTLHKLN Q29RI2_BOVIN Q29RI2_BOVIN ---------------------MKRGELFDYLTEKVTLSEKETRKIMRALLEVIATLHRLN PHKG1_MOUSE PHKG1_MOUSE ---------------------MKRGELFDYLTEKVTLTEKETRKIMRALLEVICTLHKLN PHKG1_RAT PHKG1_RAT ---------------------MKRGELFDYLTEKVTLTEKETRKIMRALLEVVCTLHKLN PHKG1_RABIT PHKG1_RABIT ---------------------MKKGELFDYLTEKVTLSEKETRKIMRALLEVICALHKLN Q6NSZ4_HUMAN Q6NSZ4_HUMAN --------------------RMKRGELFDYLTEKATLSEKETRKIMRALLEVICTLHKLN B7Z6U2_HUMAN B7Z6U2_HUMAN ---------------------MKRGELFDYLTEKVTLSEKETRKIMRALLEVICTLHKLN B2R757_HUMAN B2R757_HUMAN ---------------------MKRGELFDYLTEKVTLSEKETRKIMRALLEVICTLHELN B7Z1D0_HUMAN B7Z1D0_HUMAN KWCLGWDSPKSTNFRAQGRARMKRGELFDYLTEKVTLSEKETRKIMRALLEVICTLHKLN PHKG1_HUMAN PHKG1_HUMAN ---------------------MKRGELFDYLTEKVTLSEKETRKIMRALLEVICTLHKLN Q75LP5_HUMAN Q75LP5_HUMAN ---------------------MKRGELFDYLTEKVTLSEKETRKIMRALLEVICTLHKLN Q5HZR1_XENLA Q5HZR1_XENLA ---------------------MKRGELFDYLTEKVTLSEKETRCIMRSLLEAVYYLHTNN PHKG2_RAT PHKG2_RAT ---------------------MRKGELFDYLTEKVALSEKETRSIMRSLLEAVNFLHVNN A6H632_MOUSE A6H632_MOUSE ---------------------MRKGELFDYLTEKVALSEKETRSIMRSLLEAVSFLHANN PHKG2_MOUSE PHKG2_MOUSE ---------------------MRKGELFDYLTEKVALSEKETRSIMRSLLEAVSFLHANN B7U172_SHEEP B7U172_SHEEP ---------------------MRKGELFDYLTEKVALSEKETRSIMRSLLEAVSFLHNNN PHKG2_BOVIN PHKG2_BOVIN ---------------------MRKGELFDYLTEKVALSEKETRSIMRSLLEAVSFLHNNN B4DEB7_HUMAN B4DEB7_HUMAN ---------------------MRKGELFDYLTEKVALSEKETRSIMRSLLEAVSFLHANN A8K0C7_HUMAN A8K0C7_HUMAN ---------------------MRKGELFDYLTEKVALSEKETRSIMRSLLEAVSFLHANN PHKG2_HUMAN PHKG2_HUMAN ---------------------MRKGELFDYLTEKVALSEKETRSIMRSLLEAVSFLHANN Q59GQ4_HUMAN Q59GQ4_HUMAN ----------------------------------------------RSLLEAVSFLHANN Q4S4Q5_TETNG Q4S4Q5_TETNG ---------------------MRRGELFDYLTEKVTLSEKETRSIMRALLEAVHYLHSLH B5X389_SALSA B5X389_SALSA ---------------------MRSGELFDYLTEKVTLSEKETRCMMRCLLEAVQYLHSLN A7YYF0_DANRE A7YYF0_DANRE ---------------------MRRGELFDYLTEKVTLSEKETRSMMRALLEAVQYLHALN B1H2F1_XENTR B1H2F1_XENTR ---------------------MRRGELFDYLTEKVTLSEKETRSMMRALLEAVQYLHALN Q6DI11_DANRE Q6DI11_DANRE ---------------------MRRGELFDYLTEKVTLSEKETRSMMRALLEAVQYLHALN Q7ZYW8_DANRE Q7ZYW8_DANRE ---------------------MRRGELFDYLTEKVTLSEKETRSMMRALLEAVQYLHALN MATCH : ***.: ** . CONSENSUS ?????????????????????M??GELFDYLTEKV?LSEKETR??MR?LLE????LH??N

Q9BLG2_HALRO Q9BLG2_HALRO IIHRDLKPENILLNDDLKLHLSDFGFAIELDDGEYLKELCGTPGYMSPEMLKCTVDPRHP A0JME5_DANRE A0JME5_DANRE IVHRDLKPENILLDDNMNIKLTDFGFAVQIAPGQKLNEVCGTPGYLAPEIIECSMDPHHQ Q503G9_DANRE Q503G9_DANRE IVHRDLKPENILLDDDVNIKLTDFGFSIQIEPGQRLNEVCGTPGYLAPEIIECSMDPKHS Q6DJ64_XENTR Q6DJ64_XENTR IVHRDLKPENILLDDDMNIKLTDFGFSCQIQEGEKLKEICGTPGYLAPEILHCSMDENHS Q7ZTP8_XENLA Q7ZTP8_XENLA IVHRDLKPENILLDDDMNIKLTDFGFSCQIPEGEKLKEICGTPGYLAPEILHCSMDENHP Q5ZJ45_CHICK Q5ZJ45_CHICK IVHRDLKPENILLDDDMNIKLTDFGFSCQLHENEKLKEICGTPGYLAPEILQCSMDDEHE B7Z5U3_HUMAN B7Z5U3_HUMAN IVHRDLKPENILLDDNMNIKLTDFGFSCQLEPGERLREVCGTPSYLAPEIIECSMNEDHP Q29RI2_BOVIN Q29RI2_BOVIN IVHRDLKPENILLDDNMNIKLTDFGFSCQLEPGEKLREVCGTPSYLAPEIIECSMNDDHP PHKG1_MOUSE PHKG1_MOUSE IVHRDLKPENILLDDNMNIKLTDFGFSCQLQPGEKLREVCGTPSYLAPEIIQCSMDDGHP PHKG1_RAT PHKG1_RAT IVHRDLKPENILLDDNMNIKLTDFGFSCQLQPGEKLREVCGTPSYLAPEIIQCSMDEGHP PHKG1_RABIT PHKG1_RABIT IVHRDLKPENILLDDDMNIKLTDFGFSCQLDPGEKLREVCGTPSYLAPEIIECSMNDNHP Q6NSZ4_HUMAN Q6NSZ4_HUMAN IVHRDLKPENILLDDNMNIKLTDFGFSCQLEPGERLREVCGTPSYLAPEIIECSMNEDHP B7Z6U2_HUMAN B7Z6U2_HUMAN IVHRDLKPENILLDDNMNIKLTDFGFSCQLEPGERLREVCGTPSYLAPEIIECSMNEDHP B2R757_HUMAN B2R757_HUMAN IVHRDLKPENILLDDNMNIKLTDFGFSCQLEPGERLREVCGTPSYLAPEIIECSMNEDHP B7Z1D0_HUMAN B7Z1D0_HUMAN IVHRDLKPENILLDDNMNIKLTDFGFSCQLEPGERLREVCGTPSYLAPEIIECSMNEDHP PHKG1_HUMAN PHKG1_HUMAN IVHRDLKPENILLDDNMNIKLTDFGFSCQLEPGERLREVCGTPSYLAPEIIECSMNEDHP Q75LP5_HUMAN Q75LP5_HUMAN IVHRDLKPENILLDDNMNIKLTDFGFSCQLEPGERLREVCGTPSYLAPEIIECSMNEDHP Q5HZR1_XENLA Q5HZR1_XENLA IVHRDLKPENILMDDCLNIKLSDFGFSCILKPNEKLRELCGTPGYLAPEILKCSMDETHP PHKG2_RAT PHKG2_RAT IVHRDLKPENILLDDNMQIRLSDFGFSCHLEPGEKLRELCGTPGYLAPEILKCSMDETHP A6H632_MOUSE A6H632_MOUSE IVHRDLKPENILLDDNMQIRLSDFGFSCHLEAGEKLRELCGTPGYLAPEILKCSMDETHP PHKG2_MOUSE PHKG2_MOUSE IVHRDLKPENILLDDNMQIRLSDFGFSCHLEAGEKLRELCGTPGYLAPEILKCSMDETHP B7U172_SHEEP B7U172_SHEEP IVHRDLKPENILLDDDMQIRLSDFGFSCHLEPGEKLRELCGTPGYLAPEILKCSMDETHP PHKG2_BOVIN PHKG2_BOVIN IVHRDLKPENILLDDNMQIRLSDFGFSCHLEPGEKLRELCGTPGYLAPEILKCSMDETHP B4DEB7_HUMAN B4DEB7_HUMAN IVHRDLKPENILLDDNMQIRLSDFGFSCHLEPGEKLRELCGTPGYLAPEILKCSMDETHP A8K0C7_HUMAN A8K0C7_HUMAN IVHRDLKPENILLDDNMQIRLSDFGFSCHLEPGEKLRELCGTPGYLAPEILKCSMDETHP PHKG2_HUMAN PHKG2_HUMAN IVHRDLKPENILLDDNMQIRLSDFGFSCHLEPGEKLRELCGTPGYLAPEILKCSMDETHP Q59GQ4_HUMAN Q59GQ4_HUMAN IVHRDLKPENILLDDNMQIRLSDFGFSCHLEPGEKLRELCGTPGYLAPEILKCSMDETHP Q4S4Q5_TETNG Q4S4Q5_TETNG IVHRDLKPENILLDDHGHIKLSDFGFSVQLQPGEKLKELCGTPGYLAPEILKCSMDDMHA B5X389_SALSA B5X389_SALSA IVHRDLKPENILLDDQGHIKLSDFGFSVQLQPGKNLRELCGTPGYLAPEILKCSMDETHQ A7YYF0_DANRE A7YYF0_DANRE IVHRDLKPENILLDDQGHLKLSDFGFSVQLGPDEKLRELCGTPGYLAPEILKCSMDDTHE B1H2F1_XENTR B1H2F1_XENTR IVHRDLKPENILLDDQGHLKLSDFGFSVQLGPDEKLRELCGTPGYLAPEILKCSMDDTHE Q6DI11_DANRE Q6DI11_DANRE IVHRDLKPENILLDDQGHLKLSDFGFSVQLGPDEKLRELCGTPGYLAPEILKCSMDDTHE Q7ZYW8_DANRE Q7ZYW8_DANRE IVHRDLKPENILLDDQGHLKLSDFGFSVQLGPDEKLRELCGTPGYLAPEILKCSMDETHE MATCH *:**********::* :::*:****: : .: *.*:****.*::**::.*::: * CONSENSUS IVHRDLKPENILLDD???I?L?DFGFS??L?PGE?L?E?CGTP?YLAPEI??CSM???H?

Q9BLG2_HALRO Q9BLG2_HALRO GYRHEVDMWACGVVMYTLLAGVPPFWHRRQIIMFRRIMEGQYSFPSPDWDDISDSSKDLI A0JME5_DANRE A0JME5_DANRE GYGAAVDLWSAGVIMFTLLAGSPPFWHRKQMLMLRMILAGNYQFTSPEWDDRSDTVKDLI Q503G9_DANRE Q503G9_DANRE GYGTAVDLWSTGVILYTLLAGSPPFWHRKQMLMLRLILAGQYQFNSPEWDDRSDTVKDLI Q6DJ64_XENTR Q6DJ64_XENTR GYGKQVDMWSCGVIMYTLLAGSPPFWHRKQMLMLRMIMSGEYHFGSPEWDDRSDTVKDLI Q7ZTP8_XENLA Q7ZTP8_XENLA GYGKEVDMWSCGVIMYTLLAGSPPFWHRKQMLMLRMIMSGEYHFGSPEWDDRSDTVKDLI Q5ZJ45_CHICK Q5ZJ45_CHICK GYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMNGDYQFGSPEWDDRSDTVKDLI B7Z5U3_HUMAN B7Z5U3_HUMAN GYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGSPEWDDYSDTVKDLV Q29RI2_BOVIN Q29RI2_BOVIN GYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGSPEWDDYSDTVKDLV PHKG1_MOUSE PHKG1_MOUSE GYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMDGKYQFGSPEWDDYSDTVKDLV PHKG1_RAT PHKG1_RAT GYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMDGKYQFGSPEWDDYSDTVKDLV PHKG1_RABIT PHKG1_RABIT GYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGSPEWDDYSDTVKDLV Q6NSZ4_HUMAN Q6NSZ4_HUMAN GYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGSPEWDDYSDTVKDLV B7Z6U2_HUMAN B7Z6U2_HUMAN GYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGSYQFGSPEWDDYSDTVKDLV B2R757_HUMAN B2R757_HUMAN GYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGSPEWDDYSDTVKDLV B7Z1D0_HUMAN B7Z1D0_HUMAN GYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGSPEWDDYSDTVKDLV PHKG1_HUMAN PHKG1_HUMAN GYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGSPEWDDYSDTVKDLV Q75LP5_HUMAN Q75LP5_HUMAN GYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGSPEWDDYSDTVKDLV Q5HZR1_XENLA Q5HZR1_XENLA GYGKEVDLWACGVIVFTLLAGSPPFWHRRQMLMLRMIMDGRFQFGSPEWDDRSSTAKDLI PHKG2_RAT PHKG2_RAT GYGKEVDLWACGVILFTLLAGSPPFWHRRQILMLRMIMEGQYQFSSPEWDDRSNTVKDLI A6H632_MOUSE A6H632_MOUSE GYGKEVDLWACGVILFTLLAGSPPFWHRRQILMLRMIMEGQYQFTSPEWDDRSNTVKDLI PHKG2_MOUSE PHKG2_MOUSE GYGKEVDLWACGVILFTLLAGSPPFWHRRQILMLRMIMEGQYQFTSPEWDDCSNTVKDLI B7U172_SHEEP B7U172_SHEEP GYGKEVDLWACGVILFTLLAGSPPFWHRRQILMLRMIMEGQYQFSSPEWDDRSDTVKDLI PHKG2_BOVIN PHKG2_BOVIN GYGKEVDLWACGVILFTLLAGSPPFWHRRQILMLRMIMEGQYQFSSPEWDDRSDTVKDLI B4DEB7_HUMAN B4DEB7_HUMAN GYGKEVDLWACGVILFTLLAGSPPFWHRRQILMLRMIMEGQYQFSSPEWDDRSSTVKDLI A8K0C7_HUMAN A8K0C7_HUMAN GYGKEVDLWACGVILFTLLAGSPPFWHRRQILMLRMIMEGQYQFSSPEWDDRSSTVKDLI PHKG2_HUMAN PHKG2_HUMAN GYGKEVDLWACGVILFTLLAGSPPFWHRRQILMLRMIMEGQYQFSSPEWDDRSSTVKDLI Q59GQ4_HUMAN Q59GQ4_HUMAN GYGKEVDLWACGVILFTLLAGSPPFWHRRQILMLRMIMEGQYQFSSPEWDDRSSTVKDLI Q4S4Q5_TETNG Q4S4Q5_TETNG GYGKEVDLWACGVILFTLLAGSPPFWHRKQMLMLRMIMEGRYQFSSPEWDDRSDTVKDLI B5X389_SALSA B5X389_SALSA GYGKEVDLWACGVILFTLLAGSPPFWHRKQLLMLRMIMEGRYQFSSPEWDDRSDTVKDLI A7YYF0_DANRE A7YYF0_DANRE GYGKEVDLWACGVILFTLLAGSPPFWHRKQLLMLRMIMEGRYQFSSPEWDDRSDTVKDLT B1H2F1_XENTR B1H2F1_XENTR GYGKEVDLWACGVILFTLLAGSPPFWHRKQLLMLRMIMEGRYQFSSPEWDDRSDTVKDLT Q6DI11_DANRE Q6DI11_DANRE GYGKEVDLWACGVILFTLLAGSPPFWHRKQLLMLRMIMEGRYQFSSPEWDDRSDTVKDLI Q7ZYW8_DANRE Q7ZYW8_DANRE GYGKEVDLWACGVILFTLLAGSPPFWHRKQLLMLRMIMEGRYQFSSPEWDDRSDTVKDLI MATCH ** **:*: **:::***** ******:*::*:* *: * : * **:*** *.: *** CONSENSUS GYGKEVD?W??GVI??TLLAGSPPFWHR?Q?LMLRMIM?G?YQF?SPEWDD?S?TVKDL?

Q9BLG2_HALRO Q9BLG2_HALRO QRFLTVSPTERITAEEALRHPFFDQVDQESRYYSKAFNAKRKFRVAILTVIATSRIVRQY A0JME5_DANRE A0JME5_DANRE SKMLVVNPEKRFTATDALNHPFFQQYVVAEVRH---FSPYRKFKVICMTVLATMRIYCNY Q503G9_DANRE Q503G9_DANRE SRLLVVDPESRYTATEALNHPFFQQYVVAEVRH---FSPYRKFKVICRTVLAAMRIYCNY Q6DJ64_XENTR Q6DJ64_XENTR ARLLVVNPERRLTADEALIHPFFQQYDVEEVRY---FSPFRKFKVVCLTVLASVRIYHYY Q7ZTP8_XENLA Q7ZTP8_XENLA ARLLIVNPERRLTADEALVHPFFQQYDVEEVRY---FSPLRKFKVVCLTVLASVRIYHYY Q5ZJ45_CHICK Q5ZJ45_CHICK SQFLVVDPQRRYTAREALAHPFFQQYDVEEVRH---FSPFRKFKVICLTVLASVRIYYQY B7Z5U3_HUMAN B7Z5U3_HUMAN SRFLVVQPQNRYTAEEALAHPFFQQYLVEEVRH---FSPRGKFKVIALTVLASVRIYYQY Q29RI2_BOVIN Q29RI2_BOVIN SRFLVVSPQRRCSAEEALAHPFFQQYVVEEVRH---FSPRGKFKVICLTVLASVRIYYQY PHKG1_MOUSE PHKG1_MOUSE SRFLVVQPQDRCSAEEALAHPFFQEYVVEEVRH---FSPRGKFKVICLTVLASVKIYYQY PHKG1_RAT PHKG1_RAT SRFLVVQPQDRCSAEEALAHPFFQEYVVEEVRH---FSPRGKFKVICLTVLASVRIYYQY PHKG1_RABIT PHKG1_RABIT SRFLVVQPQKRYTAEEALAHPFFQQYVVEEVRH---FSPRGKFKVICLTVLASVRIYYQY Q6NSZ4_HUMAN Q6NSZ4_HUMAN SRFLVVQPQNRYTAEEALAHPFFQQYLVEEVRH---FSPRGKFKVIALTVLASVRIYYQY B7Z6U2_HUMAN B7Z6U2_HUMAN SRFLVVQPQNRYTAEEALAHPFFQQYLVEEVRH---FSPRGKFKVIALTVLASVRIYYQY B2R757_HUMAN B2R757_HUMAN SRFLVVQPQNRYTAEEALAHPFFQQYLVEEVRH---FSPRGKFKVIALTVLASVRIYYQY B7Z1D0_HUMAN B7Z1D0_HUMAN SRFLVVQPQNRYTAEEALAHPFFQQYLVEEVRH---FSPRGKFKVIALTVLASVRIYYQY PHKG1_HUMAN PHKG1_HUMAN SRFLVVQPQNRYTAEEALAHPFFQQYLVEEVRH---FSPRGKFKVIALTVLASVRIYYQY Q75LP5_HUMAN Q75LP5_HUMAN SRFLVVQPQNRYTAEEALAHPFFQQYLVEEVRH---FSPRGKFKVIALTVLASVRIYYQY Q5HZR1_XENLA Q5HZR1_XENLA SRLLEVCPEKRLTAEQALQHSFFQSHQRDQDTP---VKRSQRFRIAAWAALACVRILVRW PHKG2_RAT PHKG2_RAT AKLLQVDPNARLTAEQALQHPFFERCKGSQPWN---LTPRQRFRVAVWTILAAGRVALSS A6H632_MOUSE A6H632_MOUSE SKLLQVDPEARLTAEQALQHPFFERCEGSQPWN---LTPRQRFRVAVWTILAAGRVALSS PHKG2_MOUSE PHKG2_MOUSE SKLLQVDPEARLTAEQALQHPFFERCEGSQPWN---LTPRQRFRVAVWTILAAGRVALSS B7U172_SHEEP B7U172_SHEEP SRLLQVDPVERLTAEQALQHPFFERCEGSQAWN---LTPRQRFRVAVWTVLAAGRVALSA PHKG2_BOVIN PHKG2_BOVIN SRLLQVDPVERLTAEQALQHPFFERCEGSQAWN---LTPRQRFRVAVWTVLAAGRVALSA B4DEB7_HUMAN B4DEB7_HUMAN SRLLQVDPEARLTAEQALQHPFFERCEGSQPWN---LTPRQRFRVAVWTVLAAGRVALST A8K0C7_HUMAN A8K0C7_HUMAN SRLLQVDPEARLTAEQALQHPFFERCEGSQPWN---LTPRQRFRVAVWTVLAAGRVALST PHKG2_HUMAN PHKG2_HUMAN SRLLQVDPEARLTAEQALQHPFFERCEGSQPWN---LTPRQRFRVAVWTVLAAGRVALST Q59GQ4_HUMAN Q59GQ4_HUMAN SRLLQVDPEARLTAEQALQHPFFERCEGSQPWN---LTPRQRFRVAVWTVLAAGRVALST Q4S4Q5_TETNG Q4S4Q5_TETNG SRLLVLEPAARLTAEQALAHPLFRLYQKEDVRL---FSPRKTFRVLIVSVLACIRIYSRY B5X389_SALSA B5X389_SALSA TRLLVVDPIVRLNAEQALAHSFFRQYQRDEVRH---FSPRKTFRVLILSVLACIRMYCRY A7YYF0_DANRE A7YYF0_DANRE SRLLVVEPTIRLTAEQALAHPFFCQYQKEDVRL---FSPRKTFKALILTVLACIRMQCRY B1H2F1_XENTR B1H2F1_XENTR SRLLVVEPTIRLTAEQALAHPFFCQYQKEDVRL---FSPRKTFKALILTVLACIRMQCRY Q6DI11_DANRE Q6DI11_DANRE SRLLVVEPTIRLTAEQALAHPFFCQYQKEDVRL---FSPRKTFKALILTVLACIRMQCRY Q7ZYW8_DANRE Q7ZYW8_DANRE SRLLVVEPTIRLTAEQALAHPFFCQYQKEDVRL---FSPRKTFKALILTVLACIRMQCRY MATCH ::* : * * .* :** *.:* . .. *: : :* :: CONSENSUS SR?L?V?P??R?TAE?AL?HPFF???????????????P???F?V???TVLA??R?????

Q9BLG2_HALRO Q9BLG2_HALRO HNPRTVRCSVAAKDPYSVKLLRRLIDASAFGIYGHWVKKAADQNRIMLFENCTRMEQLQQ A0JME5_DANRE A0JME5_DANRE RRAKPVTKEVIKSDPYAVKPIRKLIDACAFKIYGHWVKKGQTQNRAALFE---------- Q503G9_DANRE Q503G9_DANRE RRAKPVTKEVIQSDPYAIKPLRKMIDACAFKIYGHWVKKGQTQNRAALFE---------- Q6DJ64_XENTR Q6DJ64_XENTR RKVKPVTKEIIVRDPYAIKPIRKLIDGCAFRIYGHWVKKGEQQNRAALFE---------- Q7ZTP8_XENLA Q7ZTP8_XENLA RKVKPVTREIIVRDPYAFKPIRKMIDGCAFRIYGHWVKKGEQQNRAALFE---------- Q5ZJ45_CHICK Q5ZJ45_CHICK RMVKAVTRELVVRDPYALKPIRKLIDACAFRTYRHWVKKGEAQNRAALFE---------- B7Z5U3_HUMAN B7Z5U3_HUMAN RRVKPVTREIVIRDPYALRPLRRLIDAYAFRIYGHWVKKGQQQNRAALFE---------- Q29RI2_BOVIN Q29RI2_BOVIN RRVKPVTREIVIRDPYALRPLRRLIDAYAFRIYGHWVKKGQQQNRAALFE---------- PHKG1_MOUSE PHKG1_MOUSE RRVKPVTREIVIRDPYALRPLRRLIDAYAFRIYGHWVKKGQQQNRAALFE---------- PHKG1_RAT PHKG1_RAT RRVKPVTREIVIRDPYALRPLRRLIDAYAFRIYGHWVKKGQQQNRAALFE---------- PHKG1_RABIT PHKG1_RABIT RRVKPVTREIVIRDPYALRPLRRLIDAYAFRIYGHWVKKGQQQNRAALFE---------- Q6NSZ4_HUMAN Q6NSZ4_HUMAN RRVKPVTREIVIRDPYALRPLRRLIDAYAFRIYGHWVKKGQQQNRAALFE---------- B7Z6U2_HUMAN B7Z6U2_HUMAN RRVKPVTREIVIRDPYALRPLRRLIDAYAFRIYGHWVKKGQQQNRAALFE---------- B2R757_HUMAN B2R757_HUMAN RRVKPVTREIVIRDPYALRPLRRLIDAYAFRIYGHWVKKGQQQNRAALFE---------- B7Z1D0_HUMAN B7Z1D0_HUMAN RRVKPVTREIVIRDPYALRPLRRLIDAYAFRIYGHWVKKGQQQNRAALFE---------- PHKG1_HUMAN PHKG1_HUMAN RRVKPVTREIVIRDPYALRPLRRLIDAYAFRIYGHWVKKGQQQNRAALFE---------- Q75LP5_HUMAN Q75LP5_HUMAN RRVKPVTREIVIRDPYALRPLRRLIDAYAFRIYGHWVKKGQQQNRAALFE---------- Q5HZR1_XENLA Q5HZR1_XENLA RRARPITSQLLMRDPYGIKGVRRLIDACAFRIYGHWVKKGERQNRAALFQ---------- PHKG2_RAT PHKG2_RAT HRLRPLTKNALLRDPYALRPVRRLIDNCAFRLYGHWVKKGEQQNRAALFQ---------- A6H632_MOUSE A6H632_MOUSE HRLRPLTKNALLRDPYALRPVRRLIDNCAFRLYGHWVKKGEQQNRAALFQ---------- PHKG2_MOUSE PHKG2_MOUSE HRLRPLTKNALLRDPYALRPVRRLIDNCAFRLYGHWVKKGEQQNRAALFQ---------- B7U172_SHEEP B7U172_SHEEP HRIRPLTKSALLRDPYALRPVRRLIDNCAFRLYGHWVKKGEQQNPAALFQ---------- PHKG2_BOVIN PHKG2_BOVIN HRIRPLTKSALLRDPYALRPVRRLIDNCAFRLYGHWVKKGEQQNRAALFQ---------- B4DEB7_HUMAN B4DEB7_HUMAN HRVRPLTKNALLRDPYALRSVRHLIDNCAFRLYGHWIRK--------------------- A8K0C7_HUMAN A8K0C7_HUMAN HRVRPLTKNALLRDPYALRSVRHLIDNCAFRLYGHWVKKGEQQNRAALFQ---------- PHKG2_HUMAN PHKG2_HUMAN HRVRPLTKNALLRDPYALRSVRHLIDNCAFRLYGHWVKKGEQQNRAALFQ---------- Q59GQ4_HUMAN Q59GQ4_HUMAN HRVRPLTKNALLRDPYALRSVRHLIDNCAFRLYGHWVKKGEQQNRAALFQ---------- Q4S4Q5_TETNG Q4S4Q5_TETNG QRVRPLTRDVLSRDPYSIRGVRKLIDGCAFRIYGHWVKKGEQQNRAALFQ---------- B5X389_SALSA B5X389_SALSA RRARPLTREVLARDPYSLKGVRKLIDGCAFRIYGHWVKKGEQQNRAALFQ---------- A7YYF0_DANRE A7YYF0_DANRE YRARPLTKELLSRDPYSIRGVRKLIDGCAFRIYGHWVKKGEQQNRAALFQ---------- B1H2F1_XENTR B1H2F1_XENTR YRARPLTKELLSRDPYSIRGVRKLIDGCAFRIYGHWVKKGEQQNRAALFQ---------- Q6DI11_DANRE Q6DI11_DANRE YRARPLTKELLSRDPYSIRGVRKLIDGCAFRIYGHWVKKGEQQNRAALFQ---------- Q7ZYW8_DANRE Q7ZYW8_DANRE YRARPLTKELLSRDPYSIRGVRKLIDGCAFRIYGHWVKKGEQQNRAALFQ---------- MATCH :.: . ***..: :*::** ** * **::* CONSENSUS ?R??P?T?????RDPY?????R?LID??AFR?YGHWVKKG?QQNRAALF???????????

Q9BLG2_HALRO Q9BLG2_HALRO AKFETEYNSSPEQSPTQDDEDFDTRLRRVSTSLSFENASYAQDIRLH A0JME5_DANRE A0JME5_DANRE -------NSPKAILLSLAAESVDSSLRMM------------------ Q503G9_DANRE Q503G9_DANRE -------NSPKVILLSIATEEMDAAQRTW------------------ Q6DJ64_XENTR Q6DJ64_XENTR -------NTAKAILLSLAAESNFM----------------------- Q7ZTP8_XENLA Q7ZTP8_XENLA -------NTAKAILLSLAAESNFTS---------------------- Q5ZJ45_CHICK Q5ZJ45_CHICK -------NTCKAVLLTLAAEEELF----------------------- B7Z5U3_HUMAN B7Z5U3_HUMAN -------NTPKAVLLSLAEEDY------------------------- Q29RI2_BOVIN Q29RI2_BOVIN -------NTPKAVLLSLAEEDF------------------------- PHKG1_MOUSE PHKG1_MOUSE -------NTPKAVLLSLAEEEDF------------------------ PHKG1_RAT PHKG1_RAT -------NTPKAVLLSLAEEEDF------------------------ PHKG1_RABIT PHKG1_RABIT -------NTPKAVLFSLAEDDY------------------------- Q6NSZ4_HUMAN Q6NSZ4_HUMAN -------NTPKAVLLSLVEEDY------------------------- B7Z6U2_HUMAN B7Z6U2_HUMAN -------NTPKAVLLSLAEEDY------------------------- B2R757_HUMAN B2R757_HUMAN -------NTPKAVLLSLAEEDY------------------------- B7Z1D0_HUMAN B7Z1D0_HUMAN -------NTPKAVLLSLAEEDY------------------------- PHKG1_HUMAN PHKG1_HUMAN -------NTPKAVLLSLAEEDY------------------------- Q75LP5_HUMAN Q75LP5_HUMAN -------NTPKAVLLSLAEEDY------------------------- Q5HZR1_XENLA Q5HZR1_XENLA -------NQPKALLLAMGDDDERDLEM-------------------- PHKG2_RAT PHKG2_RAT -------HQPPRPFPIIATDLEGDSSAITEDEVTLVRS--------- A6H632_MOUSE A6H632_MOUSE -------HQPPRLFPIAATELEGDSGAITEDEATLVRS--------- PHKG2_MOUSE PHKG2_MOUSE -------HQPPRLFPIAATELEGDSGAITEDEATLVRS--------- B7U172_SHEEP B7U172_SHEEP -------HRLPGPFPMMGPEEEGDSAAIAEDEAMLVLG--------- PHKG2_BOVIN PHKG2_BOVIN -------HRPPGPFPMMGPEEEGDSATIAEDEAMLVLG--------- B4DEB7_HUMAN B4DEB7_HUMAN -------QWIGKLMACV------------------------------ A8K0C7_HUMAN A8K0C7_HUMAN -------HPPPGPFPIMGPEEEGDSAAITEDEAVLVLG--------- PHKG2_HUMAN PHKG2_HUMAN -------HRPPGPFPIMGPEEEGDSAAITEDEAVLVLG--------- Q59GQ4_HUMAN Q59GQ4_HUMAN -------HRPPGPFPIMGPEEEGDSAAITEDEAVLVLG--------- Q4S4Q5_TETNG Q4S4Q5_TETNG -------N--------------------------------------- B5X389_SALSA B5X389_SALSA -------NTAKIMLLGLEDFET------------------------- A7YYF0_DANRE A7YYF0_DANRE -------NTAKIILLGLEDLEN------------------------- B1H2F1_XENTR B1H2F1_XENTR -------NTAKIILLGLEDLEN------------------------- Q6DI11_DANRE Q6DI11_DANRE -------NTAKIILLGLEDLEN------------------------- Q7ZYW8_DANRE Q7ZYW8_DANRE -------NTAKIILLGLEDLEN------------------------- MATCH : CONSENSUS ???????????????????????????????????????????????


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