Alignment of the gene Family HBG108248 of HOVERGEN

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Threshold: 50% 80% 100%
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Isoforms are ON
Q4SGZ9_TETNG Q4SGZ9_TETNG ------------ELYFLIARFLEAGPCQKA Q05BL7_MOUSE Q05BL7_MOUSE SRERKGLSELRSELYFLIARFLEDGPCQQA A7J992_HUMAN A7J992_HUMAN SCERKGLSELRSELYFLIARFLEDGPCQQA PHIP_HUMAN PHIP_HUMAN SCERKGLSELRSELYFLIARFLEDGPCQQA PHIP_MOUSE PHIP_MOUSE SRERKGLSELRSELYFLIARFLEDGPCQQA Q05CQ5_MOUSE Q05CQ5_MOUSE SRERKGLSELRSELYFLIARFLEDGPCQQA BRWD3_HUMAN BRWD3_HUMAN --MAAAPTQIEAELYYLIARFLQSGPCNKS BRWD3_MOUSE BRWD3_MOUSE --MAAAPTQIEAELYYLIARFLQSGPCNKS Q6NSN0_DANRE Q6NSN0_DANRE ------------------------------ Q4S8S0_TETNG Q4S8S0_TETNG -----------SELYYLIARFLQSGPCKKA MATCH CONSENSUS ????????????ELY?LIARFL??GPC???

Q4SGZ9_TETNG Q4SGZ9_TETNG AETLIREVEEKELLPKRLDWTGQEHPGTYE Q05BL7_MOUSE Q05BL7_MOUSE AQVLIREVAEKELLPRRTDWTGKEHPRTYQ A7J992_HUMAN A7J992_HUMAN AQVLIREVAEKELLPRRTDWTGKEHPRTYQ PHIP_HUMAN PHIP_HUMAN AQVLIREVAEKELLPRRTDWTGKEHPRTYQ PHIP_MOUSE PHIP_MOUSE AQVLIREVAEKELLPRRTDWTGKEHPRTYQ Q05CQ5_MOUSE Q05CQ5_MOUSE AQVLIREVAEKELLPRRTDWTGKEHPRTYQ BRWD3_HUMAN BRWD3_HUMAN AQVLVQELEEHQLIPRRLDWEGKEHRRSFE BRWD3_MOUSE BRWD3_MOUSE AQVLVQELEEHQLIPRRLDWEGKEHRRSFE Q6NSN0_DANRE Q6NSN0_DANRE ------------------------------ Q4S8S0_TETNG Q4S8S0_TETNG AQILIEELEEYELVPERWSWDGKKYKQTFQ MATCH CONSENSUS AQ?L??E??E??L?P?R?DW?GKEH?????

Q4SGZ9_TETNG Q4SGZ9_TETNG NLVKLYRHVSADHLLQVCSKVCPLLEREVP Q05BL7_MOUSE Q05BL7_MOUSE NLVKYYRHLAPDHLLQICHRLGPLLEQEIP A7J992_HUMAN A7J992_HUMAN NLVKYYRHLAPDHLLQICHRLGPLLEQEIP PHIP_HUMAN PHIP_HUMAN NLVKYYRHLAPDHLLQICHRLGPLLEQEIP PHIP_MOUSE PHIP_MOUSE NLVKYYRHLAPDHLLQICHRLGPLLEQEIP Q05CQ5_MOUSE Q05CQ5_MOUSE NLVKYYRHLAPDHLLQICHRLGPLLEQEIP BRWD3_HUMAN BRWD3_HUMAN DLVAANAHIPPDYLLKICERIGPLLDKEIP BRWD3_MOUSE BRWD3_MOUSE DLVAANAHIPPDYLLKICERIGPLLDKEIP Q6NSN0_DANRE Q6NSN0_DANRE ------------------------------ Q4S8S0_TETNG Q4S8S0_TETNG DWVIVNEHIPADYLLRVCQRIGPLIEKEVP MATCH CONSENSUS ?LV????H???D?LL??C?R?GPLL??E?P

Q4SGZ9_TETNG Q4SGZ9_TETNG ASVPGLTSLLGAGRQNLLRTSKS------- Q05BL7_MOUSE Q05BL7_MOUSE QSVPGVQTLLGAGRQSLLRTNKS------- A7J992_HUMAN A7J992_HUMAN QSVPGVQTLLGAGRQSLLRTNKS------- PHIP_HUMAN PHIP_HUMAN QSVPGVQTLLGAGRQSLLRTNKS------- PHIP_MOUSE PHIP_MOUSE QSVPGVQTLLGAGRQSLLRTNKS------- Q05CQ5_MOUSE Q05CQ5_MOUSE QSVPGVQTLLGAGRQSLLRTNKS------- BRWD3_HUMAN BRWD3_HUMAN QSVPGVQTLLGVGRQSLLRDAKD------- BRWD3_MOUSE BRWD3_MOUSE QSVPGVQTLLGVGRQSLLRDAKD------- Q6NSN0_DANRE Q6NSN0_DANRE ------------------------------ Q4S8S0_TETNG Q4S8S0_TETNG PSVPGVQTLLGLGKQSLLRTSKSKYFLSHL MATCH CONSENSUS ?SVPGVQTLLG?GRQSLLR??K????????

Q4SGZ9_TETNG Q4SGZ9_TETNG ----------------------CKHVVWKG Q05BL7_MOUSE Q05BL7_MOUSE ----------------------CKHVVWKG A7J992_HUMAN A7J992_HUMAN ----------------------CKHVVWKG PHIP_HUMAN PHIP_HUMAN ----------------------CKHVVWKG PHIP_MOUSE PHIP_MOUSE ----------------------CKHVVWKG Q05CQ5_MOUSE Q05CQ5_MOUSE ----------------------CKHVVWKG BRWD3_HUMAN BRWD3_HUMAN ----------------------CKSTLWNG BRWD3_MOUSE BRWD3_MOUSE ----------------------CKSTLWNG Q6NSN0_DANRE Q6NSN0_DANRE ------------------------------ Q4S8S0_TETNG Q4S8S0_TETNG HSLGFNINSISTYRLTCFCDLGCIHKVCSG MATCH CONSENSUS ??????????????????????CK???W?G

Q4SGZ9_TETNG Q4SGZ9_TETNG SALAALHCGRPPEPPVIYGSPPNIDVDDSD Q05BL7_MOUSE Q05BL7_MOUSE SALAALHCGRPPESPVNYGSPPSI------ A7J992_HUMAN A7J992_HUMAN SALAALHCGRPPESPVNYGSPPSI------ PHIP_HUMAN PHIP_HUMAN SALAALHCGRPPESPVNYGSPPSI------ PHIP_MOUSE PHIP_MOUSE SALAALHCGRPPESPVNYGSPPSI------ Q05CQ5_MOUSE Q05CQ5_MOUSE SALAALHCGRPPESPVNYGSPPSI------ BRWD3_HUMAN BRWD3_HUMAN SAFAALHRGRPPELPVNYVKPPNV------ BRWD3_MOUSE BRWD3_MOUSE SAFAALHRGRPPELPVNYVKPPNV------ Q6NSN0_DANRE Q6NSN0_DANRE -----------------AGGPLS------- Q4S8S0_TETNG Q4S8S0_TETNG SSIAALHRGRPPEPPVINGGPPNV------ MATCH * . CONSENSUS SA?AALH?GRPPE?PV?YG?PP????????

Q4SGZ9_TETNG Q4SGZ9_TETNG ETSSILIVVETSFSRRLNGSYRLRQLVPTA Q05BL7_MOUSE Q05BL7_MOUSE --------ADTLFSRKLNGKYRLERLVPTA A7J992_HUMAN A7J992_HUMAN --------ADTLFSRKLNGKYRLERLVPTA PHIP_HUMAN PHIP_HUMAN --------ADTLFSRKLNGKYRLERLVPTA PHIP_MOUSE PHIP_MOUSE --------ADTLFSRKLNGKYRLERLVPTA Q05CQ5_MOUSE Q05CQ5_MOUSE --------ADTLFSRKLNGKYRLERLVPTA BRWD3_HUMAN BRWD3_HUMAN --------VNITSARQLTGCSRFGHIFPSS BRWD3_MOUSE BRWD3_MOUSE --------VNITSARQLTGCSRFSHVFPSS Q6NSN0_DANRE Q6NSN0_DANRE ------------------------------ Q4S8S0_TETNG Q4S8S0_TETNG --------VSTMAARQATGTARFSQVLPSS MATCH CONSENSUS ??????????????R?L?G??R?????P??

Q4SGZ9_TETNG Q4SGZ9_TETNG VYQHMKMHKRILGHLSSVYCVTFDRTGRRI Q05BL7_MOUSE Q05BL7_MOUSE VYQHMKMHKRILGHLSSVYCVTFDRTGRRI A7J992_HUMAN A7J992_HUMAN VYQHMKMHKRILGHLSSVYCVTFDRTGRRI PHIP_HUMAN PHIP_HUMAN VYQHMKMHKRILGHLSSVYCVTFDRTGRRI PHIP_MOUSE PHIP_MOUSE VYQHMKMHKRILGHLSSVYCVTFDRTGRRI Q05CQ5_MOUSE Q05CQ5_MOUSE VYQHMKMHKRILGHLSSVYCVTFDRTGRRI BRWD3_HUMAN BRWD3_HUMAN AYQHIKMHKRILGHLSSVYCVAFDRSGRRI BRWD3_MOUSE BRWD3_MOUSE AYQHIKMHKRILGHLSSVYCVAFDRSGRRI Q6NSN0_DANRE Q6NSN0_DANRE ------------------------------ Q4S8S0_TETNG Q4S8S0_TETNG SYQHMKIHKRILGHLSSVYCVVFDRTGRRI MATCH CONSENSUS ?YQH?KMHKRILGHLSSVYCV?FDR?GRRI

Q4SGZ9_TETNG Q4SGZ9_TETNG FTGSDDCLVKIWGTDDGRLLATLRGHAAEI Q05BL7_MOUSE Q05BL7_MOUSE FTGSDDCLVKIWATDDGRLLATLRGHAAEI A7J992_HUMAN A7J992_HUMAN FTGSDDCLVKIWATDDGRLLATLRGHAAEI PHIP_HUMAN PHIP_HUMAN FTGSDDCLVKIWATDDGRLLATLRGHAAEI PHIP_MOUSE PHIP_MOUSE FTGSDDCLVKIWATDDGRLLATLRGHAAEI Q05CQ5_MOUSE Q05CQ5_MOUSE FTGSDDCLVKIWATDDGRLLATLRGHAAEI BRWD3_HUMAN BRWD3_HUMAN FTGSDDCLVKIWATDDGRLLATLRGHSAEI BRWD3_MOUSE BRWD3_MOUSE FTGSDDCLVKIWATDDGRLLATLRGHSAEI Q6NSN0_DANRE Q6NSN0_DANRE ------------------------------ Q4S8S0_TETNG Q4S8S0_TETNG FTGSDDCLVKIWATDDGRFLATLRGHSAEI MATCH CONSENSUS FTGSDDCLVKIWATDDGRLLATLRGH?AEI

Q4SGZ9_TETNG Q4SGZ9_TETNG SDMAVSYENTMIAAGSCDKTIRVWCLQTCA Q05BL7_MOUSE Q05BL7_MOUSE SDMAVNYENTMIAAGSCDKMIRVWCLRTCA A7J992_HUMAN A7J992_HUMAN SDMAVNYENTMIAAGSCDKMIRVWCLRTCA PHIP_HUMAN PHIP_HUMAN SDMAVNYENTMIAAGSCDKMIRVWCLRTCA PHIP_MOUSE PHIP_MOUSE SDMAVNYENTMIAAGSCDKMIRVWCLRTCA Q05CQ5_MOUSE Q05CQ5_MOUSE SDMAVNYENTMIAAGSCDKMIRVWCLRTCA BRWD3_HUMAN BRWD3_HUMAN SDMAVNYENTLIAAGSCDKVVRVWCLRTCA BRWD3_MOUSE BRWD3_MOUSE SDMAVNYENTLIAAGSCDKVVRVWCLRTCA Q6NSN0_DANRE Q6NSN0_DANRE ------------------------------ Q4S8S0_TETNG Q4S8S0_TETNG CDMAVNYENTLIASASCDKTIRVWC---CG MATCH CONSENSUS SDMAVNYENT?IAAGSCDK??RVWCL?TCA

Q4SGZ9_TETNG Q4SGZ9_TETNG PLAVLEGHAASITSLQFSPLCSGSKRYLSS Q05BL7_MOUSE Q05BL7_MOUSE PLAVLQGHSASITSLQFSPLCSGSKRYLSS A7J992_HUMAN A7J992_HUMAN PLAVLQGHSASITSLQFSPLCSGSKRYLSS PHIP_HUMAN PHIP_HUMAN PLAVLQGHSASITSLQFSPLCSGSKRYLSS PHIP_MOUSE PHIP_MOUSE PLAVLQGHSASITSLQFSPLCSGSKRYLSS Q05CQ5_MOUSE Q05CQ5_MOUSE PLAVLQGHSASITSLQFSPLCSGSKRYLSS BRWD3_HUMAN BRWD3_HUMAN PVAVLQGHSASITSIQFCPSTKGTNRYLTS BRWD3_MOUSE BRWD3_MOUSE PVAVLQGHSASITSIQFCPSTKGTTRYLTS Q6NSN0_DANRE Q6NSN0_DANRE ------------------------------ Q4S8S0_TETNG Q4S8S0_TETNG PVHL-------------------------- MATCH CONSENSUS P?AVL?GH?ASITS?QF?P???G??RYL?S

Q4SGZ9_TETNG Q4SGZ9_TETNG TGADGTICFWQWDSRTLKFGQRPSKFTERS Q05BL7_MOUSE Q05BL7_MOUSE TGADGTICFWLWDAGTLKINPRPTKFTERP A7J992_HUMAN A7J992_HUMAN TGADGTICFWLWDAGTLKINPRPAKFTERP PHIP_HUMAN PHIP_HUMAN TGADGTICFWLWDAGTLKINPRPAKFTERP PHIP_MOUSE PHIP_MOUSE TGADGTICFWLWDAGTLKINPRPTKFTERP Q05CQ5_MOUSE Q05CQ5_MOUSE TGADGTICFWLWDAGTLKINPRPTKFTERP BRWD3_HUMAN BRWD3_HUMAN TGADGTICFWQWHVKTMKFRDRPVKFTERS BRWD3_MOUSE BRWD3_MOUSE TGADGTICFWQWHVKTMKFRDRPVKFTERS Q6NSN0_DANRE Q6NSN0_DANRE ------------------------------ Q4S8S0_TETNG Q4S8S0_TETNG -----SVCCRPTLPPSHPFSDQPVKFVERS MATCH CONSENSUS TGADGTICFW?W???T?K???RP?KFTER?

Q4SGZ9_TETNG Q4SGZ9_TETNG RPGVQMICSSFSAGGMFLATGSTDHIIRVY Q05BL7_MOUSE Q05BL7_MOUSE RPGVQMICSSFSAGGMFLATGSTDHIIRVY A7J992_HUMAN A7J992_HUMAN RPGVQMICSSFSAGGMFLATGSTDHIIRVY PHIP_HUMAN PHIP_HUMAN RPGVQMICSSFSAGGMFLATGSTDHIIRVY PHIP_MOUSE PHIP_MOUSE RPGVQMICSSFSAGGMFLATGSTDHIIRVY Q05CQ5_MOUSE Q05CQ5_MOUSE RPGVQMICSSFSAGGMFLATGSTDHIIRVY BRWD3_HUMAN BRWD3_HUMAN RPGVQISCSSFSSGGMFITTGSTDHVIRIY BRWD3_MOUSE BRWD3_MOUSE RPGVQISCSSFSSGGMFITTGSTDHVIRIY Q6NSN0_DANRE Q6NSN0_DANRE ------------------------------ Q4S8S0_TETNG Q4S8S0_TETNG RPGVQVSTSSFSSGGMFMATGSTDHMIRVY MATCH CONSENSUS RPGVQ??CSSFS?GGMF??TGSTDH?IR?Y

Q4SGZ9_TETNG Q4SGZ9_TETNG YFGSGQPEKISELESHTDKVDSIQFSHCSD Q05BL7_MOUSE Q05BL7_MOUSE FFGSGQPEKISELEFHTDKVDSIQFSNTSN A7J992_HUMAN A7J992_HUMAN FFGSGQPEKISELEFHTDKVDSIQFSNTSN PHIP_HUMAN PHIP_HUMAN FFGSGQPEKISELEFHTDKVDSIQFSNTSN PHIP_MOUSE PHIP_MOUSE FFGSGQPEKISELEFHTDKVDSIQFSNTSN Q05CQ5_MOUSE Q05CQ5_MOUSE FFGSGQPEKISELEFHTDKVDSIQFSNTSN BRWD3_HUMAN BRWD3_HUMAN YLGSEVPEKIAELESHTDKVVAVQFCNNGD BRWD3_MOUSE BRWD3_MOUSE YLGSEIPEKIAELESHTDKVVAVQFCNNGD Q6NSN0_DANRE Q6NSN0_DANRE ------------------------------ Q4S8S0_TETNG Q4S8S0_TETNG YLGAETPMKVAEMDAHTDKVVVVQFSNSSD MATCH CONSENSUS ??GS??PEKI?ELE?HTDKV???QF?N???

Q4SGZ9_TETNG Q4SGZ9_TETNG --RFVSGSRDGTARIWQLQPQGWRSILLDM Q05BL7_MOUSE Q05BL7_MOUSE --RFVSGSRDGTARIWQFKRREWKSILLDM A7J992_HUMAN A7J992_HUMAN --RFVSGSRDGTARIWQFKRREWKSILLDM PHIP_HUMAN PHIP_HUMAN --RFVSGSRDGTARIWQFKRREWKSILLDM PHIP_MOUSE PHIP_MOUSE --RFVSGSRDGTARIWQFKRREWKSILLDM Q05CQ5_MOUSE Q05CQ5_MOUSE --RFVSGSRDGTARIWQFKRREWKSILLDM BRWD3_HUMAN BRWD3_HUMAN SLRFVSGSRDGTARIWQYQQQEWKSIVLDM BRWD3_MOUSE BRWD3_MOUSE SLRFVSGSRDGTARIWQYQQQEWKSIVLDM Q6NSN0_DANRE Q6NSN0_DANRE ------------------------------ Q4S8S0_TETNG Q4S8S0_TETNG SLRFVSGSRDGTAKIWRYQQQEWKAISLDM MATCH CONSENSUS ??RFVSGSRDGTARIWQ????EWKSI?LDM

Q4SGZ9_TETNG Q4SGZ9_TETNG QTKLPGKYNPPPLEDKVTKLKVTMVAWDRH Q05BL7_MOUSE Q05BL7_MOUSE ATRPAGQ-NLQGIEDKITKMKVTMVAWDRH A7J992_HUMAN A7J992_HUMAN ATRPAGQ-NLQGIEDKITKMKVTMVAWDRH PHIP_HUMAN PHIP_HUMAN ATRPAGQ-NLQGIEDKITKMKVTMVAWDRH PHIP_MOUSE PHIP_MOUSE ATRPAGQ-NLQGIEDKITKMKVTMVAWDRH Q05CQ5_MOUSE Q05CQ5_MOUSE ATRPAGQ-NLQGIEDKITKMKVTMVAWDRH BRWD3_HUMAN BRWD3_HUMAN ATKMTGN-NLPSGEDKITKLKVTMVAWDRY BRWD3_MOUSE BRWD3_MOUSE ATKMSGN-NLTSAEDKVTKLKVTMVAWDRY Q6NSN0_DANRE Q6NSN0_DANRE ------------------------------ Q4S8S0_TETNG Q4S8S0_TETNG AAKLPGN-TVANGDDK-TKLVVTMVAWDRA MATCH CONSENSUS AT???G??N????EDK?TK?KVTMVAWDR?

Q4SGZ9_TETNG Q4SGZ9_TETNG DSTVITAANNLTLKVWNSTTGNLIHVLMGH Q05BL7_MOUSE Q05BL7_MOUSE DNTVITAVNNMTLKVWNSYTGQLIHVLMGH A7J992_HUMAN A7J992_HUMAN DNTVITAVNNMTLKVWNSYTGQLIHVLMGH PHIP_HUMAN PHIP_HUMAN DNTVITAVNNMTLKVWNSYTGQLIHVLMGH PHIP_MOUSE PHIP_MOUSE DNTVITAVNNMTLKVWNSYTGQLIHVLMGH Q05CQ5_MOUSE Q05CQ5_MOUSE DNTVITAVNNMTLKVWNSYTGQLIHVLMGH BRWD3_HUMAN BRWD3_HUMAN DTTVITAVNNFLLKVWNSITGQLLHTLSGH BRWD3_MOUSE BRWD3_MOUSE DTTVITAVNNFLLKVWNSVTGQLLHTLSGH Q6NSN0_DANRE Q6NSN0_DANRE ------------------------------ Q4S8S0_TETNG Q4S8S0_TETNG DTSVITAVSNYLLKVWSSTTGQLLHVLSGH MATCH CONSENSUS D?TVITAVNN??LKVWNS?TGQL?H?L?GH

Q4SGZ9_TETNG Q4SGZ9_TETNG EDEVFVLESHPFDPRILFSAGHDGNCIVWD Q05BL7_MOUSE Q05BL7_MOUSE EDEVFVLEPHPFDPRVLFSAGHDGNVIVWD A7J992_HUMAN A7J992_HUMAN EDEVFVLEPHPFDPRVLFSAGHDGNVIVWD PHIP_HUMAN PHIP_HUMAN EDEVFVLEPHPFDPRVLFSAGHDGNVIVWD PHIP_MOUSE PHIP_MOUSE EDEVFVLEPHPFDPRVLFSAGHDGNVIVWD Q05CQ5_MOUSE Q05CQ5_MOUSE EDEVFVLEPHPFDPRVLFSAGHDGNVIVWD BRWD3_HUMAN BRWD3_HUMAN DDEVFVLEAHPFDQRIILSAGHDGNIFIWD BRWD3_MOUSE BRWD3_MOUSE DDEVFVLEAHPFDQRIILSAGHDGNIFIWD Q6NSN0_DANRE Q6NSN0_DANRE ------------------------------ Q4S8S0_TETNG Q4S8S0_TETNG DDEVFVMEAHPFDSRILLSAGHDGNIYMWD MATCH CONSENSUS ?DEVFVLE?HPFD?R???SAGHDGN???WD

Q4SGZ9_TETNG Q4SGZ9_TETNG LARGVKIRSYFNM-------IEGQGHGALF Q05BL7_MOUSE Q05BL7_MOUSE LARGVKVRSYFNM-------IEGQGHGAVF A7J992_HUMAN A7J992_HUMAN LARGVKIRSYFNM-------IEGQGHGAVF PHIP_HUMAN PHIP_HUMAN LARGVKIRSYFNM-------IEGQGHGAVF PHIP_MOUSE PHIP_MOUSE LARGVKVRSYFNM-------IEGQGHGAVF Q05CQ5_MOUSE Q05CQ5_MOUSE LARGVKVRSYFNM-------IEGQGHGAVF BRWD3_HUMAN BRWD3_HUMAN LDRGTKIRNYFNM-------IEGQGHGAVF BRWD3_MOUSE BRWD3_MOUSE LDRGTKIRNYFNM-------IEGQGHGAVF Q6NSN0_DANRE Q6NSN0_DANRE ------------------------------ Q4S8S0_TETNG Q4S8S0_TETNG LTKGAKIRNFFNMVTQHRGQIEGQGHGAIF MATCH CONSENSUS L?RG?K?R?YFNM???????IEGQGHGA?F

Q4SGZ9_TETNG Q4SGZ9_TETNG DCKCSPDGQHFAATDSHGHLLIFGFGSSSK Q05BL7_MOUSE Q05BL7_MOUSE DCKCSPDGQHFACTDSHGHLLIFGFGSSSK A7J992_HUMAN A7J992_HUMAN DCKCSPDGQHFACTDSHGHLLIFGFGSSSK PHIP_HUMAN PHIP_HUMAN DCKCSPDGQHFACTDSHGHLLIFGFGSSSK PHIP_MOUSE PHIP_MOUSE DCKCSPDGQHFACTDSHGHLLIFGFGSSSK Q05CQ5_MOUSE Q05CQ5_MOUSE DCKCSPDGQHFACTDSHGHLLIFGFGSSSK BRWD3_HUMAN BRWD3_HUMAN DCKFSPDGNHFACTDSHGHLLLFGFGCSKY BRWD3_MOUSE BRWD3_MOUSE DCKFSPDGNHFACTDSHGHLLLFGFGCSKY Q6NSN0_DANRE Q6NSN0_DANRE ------------------------------ Q4S8S0_TETNG Q4S8S0_TETNG DCKFSIDGQHFACTDSHGHLLIFGFGCSKP MATCH CONSENSUS DCK?SPDG?HFACTDSHGHLL?FGFG?S??

Q4SGZ9_TETNG Q4SGZ9_TETNG YDKIADQMFFHTDYRPLIRDANNYVLDEQT Q05BL7_MOUSE Q05BL7_MOUSE YDKIADQMFFHSDYRPLIRDANNFVLDEQT A7J992_HUMAN A7J992_HUMAN YDKIADQMFFHSDYRPLIRDANNFVLDEQT PHIP_HUMAN PHIP_HUMAN YDKIADQMFFHSDYRPLIRDANNFVLDEQT PHIP_MOUSE PHIP_MOUSE YDKIADQMFFHSDYRPLIRDANNFVLDEQT Q05CQ5_MOUSE Q05CQ5_MOUSE YDKIADQMFFHSDYRPLIRDANNFVLDEQT BRWD3_HUMAN BRWD3_HUMAN YEKIPDQMFFHTDYRPLIRDANNYVLDEQT BRWD3_MOUSE BRWD3_MOUSE YEKIPDQMFFHTDYRPLIRDANNYVLDEQT Q6NSN0_DANRE Q6NSN0_DANRE ------------------------------ Q4S8S0_TETNG Q4S8S0_TETNG FEK--------------------------- MATCH CONSENSUS Y?KI?DQMFFH?DYRPLIRDANN?VLDEQT

Q4SGZ9_TETNG Q4SGZ9_TETNG QQAPHLMPPPFLVDVDGNPHPPRYQRLVPG Q05BL7_MOUSE Q05BL7_MOUSE QQAPHLMPPPFLVDVDGNPHPSRYQRLVPG A7J992_HUMAN A7J992_HUMAN QQAPHLMPPPFLVDVDGNPHPSRYQRLVPG PHIP_HUMAN PHIP_HUMAN QQAPHLMPPPFLVDVDGNPHPSRYQRLVPG PHIP_MOUSE PHIP_MOUSE QQAPHLMPPPFLVDVDGNPHPSRYQRLVPG Q05CQ5_MOUSE Q05CQ5_MOUSE QQAPHLMPPPFLVDVDGNPHPSRYQRLVPG BRWD3_HUMAN BRWD3_HUMAN QQAPHLMPPPFLVDVDGNPHPTKFQRLVPG BRWD3_MOUSE BRWD3_MOUSE QQAPHLMPPPFLVDVDGNPHPTKFQRLVPG Q6NSN0_DANRE Q6NSN0_DANRE ------------------------------ Q4S8S0_TETNG Q4S8S0_TETNG -------------------------RMDAG MATCH CONSENSUS QQAPHLMPPPFLVDVDGNPHP???QRLVPG

Q4SGZ9_TETNG Q4SGZ9_TETNG -REGCRDEQLIPQMGVTSSG----LNQVVS Q05BL7_MOUSE Q05BL7_MOUSE -RENCREEQLIPQMGVTSSG----LNQVLS A7J992_HUMAN A7J992_HUMAN -RENCREEQLIPQMGVTSSG----LNQVLS PHIP_HUMAN PHIP_HUMAN -RENCREEQLIPQMGVTSSG----LNQVLS PHIP_MOUSE PHIP_MOUSE -RENCREEQLIPQMGVTSSG----LNQVLS Q05CQ5_MOUSE Q05CQ5_MOUSE -RENCREEQLIPQMGVTSSG----LNQVLS BRWD3_HUMAN BRWD3_HUMAN -RENCKDEQLIPQLGYVANGDGEVVEQVIG BRWD3_MOUSE BRWD3_MOUSE -RENCKDEQLIPQLGYVANGDGEVVEQVIG Q6NSN0_DANRE Q6NSN0_DANRE -----------P------------------ Q4S8S0_TETNG Q4S8S0_TETNG IRGKCNWEILNPHLSFCLLGDGELVEQVLG MATCH * CONSENSUS ?RE?C??EQLIPQ?G????G??????QV??

Q4SGZ9_TETNG Q4SGZ9_TETNG EQAV-DGPSPLDTMIQRLQQEQD-QRLGTG Q05BL7_MOUSE Q05BL7_MOUSE QQAN-QDISPLDSMIQRLQQEQDLRRSGEA A7J992_HUMAN A7J992_HUMAN QQAN-QEISPLDSMIQRLQQEQDLRRSGEA PHIP_HUMAN PHIP_HUMAN QQAN-QEISPLDSMIQRLQQEQDLRRSGEA PHIP_MOUSE PHIP_MOUSE QQAN-QDISPLDSMIQRLQQEQDLRRSGEA Q05CQ5_MOUSE Q05CQ5_MOUSE QQAN-QDISPLDSMIQRLQQEQDLRRSGEA BRWD3_HUMAN BRWD3_HUMAN QQTNDQDESILDGIIRELQREQDLRLINEG BRWD3_MOUSE BRWD3_MOUSE QQTNDQEESILDGIIRELQREQDLRLINEG Q6NSN0_DANRE Q6NSN0_DANRE ------------------------------ Q4S8S0_TETNG Q4S8S0_TETNG QQTAENRESLLDNLIRQLQNEQDERHIAAR MATCH CONSENSUS QQ??????S?LD??I??LQ?EQD?R?????

Q4SGZ9_TETNG Q4SGZ9_TETNG DTSGAALANTRAGRGSVGSSP-EVHSPPNV Q05BL7_MOUSE Q05BL7_MOUSE GVS----NASRVNRGSVSSTS-EVHSPPNI A7J992_HUMAN A7J992_HUMAN GIS----NTSRLSRGSISSTS-EVHSPPNV PHIP_HUMAN PHIP_HUMAN GIS----NTSRLSRGSISSTS-EVHSPPNV PHIP_MOUSE PHIP_MOUSE GVS----NASRVNRGSVSSTS-EVHSPPNI Q05CQ5_MOUSE Q05CQ5_MOUSE GVS----NASRVNRGSVSSTS-EVHSPPNI BRWD3_HUMAN BRWD3_HUMAN DVPHLPVNRAYSVNGALRSPNMDISSSPNI BRWD3_MOUSE BRWD3_MOUSE DVPHFPINRSYSVNGALSSPNMDIPSSPNI Q6NSN0_DANRE Q6NSN0_DANRE ---------------------------PNV Q4S8S0_TETNG Q4S8S0_TETNG QA-----EEAAAAAAEEGEAEVEVVVAPSA MATCH *. CONSENSUS ??????????????G???S??????S?PN?

Q4SGZ9_TETNG Q4SGZ9_TETNG GLRR-SGQIEGVRQMHSNAPRSQMATEGDL Q05BL7_MOUSE Q05BL7_MOUSE GLRR-SGQIEGVRQMHSNAPRSEIATERDL A7J992_HUMAN A7J992_HUMAN GLRR-SGQIEGVRQMHSNAPRSEIATERDL PHIP_HUMAN PHIP_HUMAN GLRR-SGQIEGVRQMHSNAPRSEIATERDL PHIP_MOUSE PHIP_MOUSE GLRR-SGQIEGVRQMHSNAPRSEIATERDL Q05CQ5_MOUSE Q05CQ5_MOUSE GLRR-SGQIEGVRQMHSNAPRSEIATERDL BRWD3_HUMAN BRWD3_HUMAN RLRRHSSQIEGVRQMHNNAPRSQMATERDL BRWD3_MOUSE BRWD3_MOUSE GLRR-SGQIEGVRQMHNNAPRSQMATERDL Q6NSN0_DANRE Q6NSN0_DANRE GLRR-SGQVEGVRQMHNNAPRSQMATERDL Q4S8S0_TETNG Q4S8S0_TETNG APRR-SGQVDGVWQMQHNTLRSQVATERDL MATCH ** *.*::** **: *: **::*** ** CONSENSUS GLRR?SGQIEGVRQMH?NAPRS??ATERDL

Q4SGZ9_TETNG Q4SGZ9_TETNG VAWSRRVLVPELEDASVRRQVNWREAKGEE Q05BL7_MOUSE Q05BL7_MOUSE VAWSRRVVVPELSAGVASRQEEWRTAKGEE A7J992_HUMAN A7J992_HUMAN VAWSRRVVVPELSAGVASRQEEWRTAKGEE PHIP_HUMAN PHIP_HUMAN VAWSRRVVVPELSAGVASRQEEWRTAKGEE PHIP_MOUSE PHIP_MOUSE VAWSRRVVVPELSAGVASRQEEWRTAKGEE Q05CQ5_MOUSE Q05CQ5_MOUSE VAWSRRVVVPELSAGVA-RQEEWRTAKGEE BRWD3_HUMAN BRWD3_HUMAN MAWSRRVVVNELNNGVSRVQEECRTAKGDI BRWD3_MOUSE BRWD3_MOUSE MAWSRRVVVNELNSGVSRVQEECRNAKGDL Q6NSN0_DANRE Q6NSN0_DANRE LAWSRRVVVNEVQAGIFRVMEDCRLAKGEV Q4S8S0_TETNG Q4S8S0_TETNG LAWSRRVMVYEVPHGVYRVSEECRRAKGDL MATCH :******:* *: . : * ***: CONSENSUS ?AWSRRVVV?EL??GV???QEE?R?AKG??

Q4SGZ9_TETNG Q4SGZ9_TETNG EINIYQSERRRRTIHSLPKESRVHLTS-EA Q05BL7_MOUSE Q05BL7_MOUSE EIKSYRSEEKRK-HLTVAKENKILTVS-KN A7J992_HUMAN A7J992_HUMAN EIKTYRSEEKRK-HLTVPKENKIPTVS-KN PHIP_HUMAN PHIP_HUMAN EIKTYRSEEKRK-HLTVPKENKIPTVS-KN PHIP_MOUSE PHIP_MOUSE EIKSYRSEEKRK-HLTVAKENKILTVS-KN Q05CQ5_MOUSE Q05CQ5_MOUSE EIKSYRSEEKRK-HLTVAKENKILTVS-KN BRWD3_HUMAN BRWD3_HUMAN EISLYTVEKKKKPSYTTQRNDYEPSCG-RS BRWD3_MOUSE BRWD3_MOUSE EVSLYTVEKKKKPSYPIQRNDYQPSCG-RS Q6NSN0_DANRE Q6NSN0_DANRE ERSYYIIEKKRK---SVPSTGSQPGDNVRT Q4S8S0_TETNG Q4S8S0_TETNG ECSFYNAERRKKPVPCTPKNEPLTTRL-RS MATCH * . * *.::: . CONSENSUS E???Y??E?K?K??????????????????

Q4SGZ9_TETNG Q4SGZ9_TETNG LVDE--------GRRSQGNHGYHTRAA--M Q05BL7_MOUSE Q05BL7_MOUSE HAHEHFLDLGDSKKQQANQHNYRTRSA--L A7J992_HUMAN A7J992_HUMAN HAHEHFLDLGESKKQQTNQHNYRTRSA--L PHIP_HUMAN PHIP_HUMAN HAHEHFLDLGESKKQQTNQHNYRTRSA--L PHIP_MOUSE PHIP_MOUSE HAHEHFLDLGDSKKQQANQHNYRTRSA--L Q05CQ5_MOUSE Q05CQ5_MOUSE HAHEHFLDLGDSKKQQANQHNYRTRSA--L BRWD3_HUMAN BRWD3_HUMAN LR----------RTQRKRQHTYQTRSN--I BRWD3_MOUSE BRWD3_MOUSE LR----------RTQRKRQHTYLTRSN--I Q6NSN0_DANRE Q6NSN0_DANRE LRRPQ-------RKAQQKRHAYQTRST--R Q4S8S0_TETNG Q4S8S0_TETNG LRP---------NKTKRQRHAYQTRSAQVR MATCH .* * **: CONSENSUS ???????????????????H?Y?TRS????

Q4SGZ9_TETNG Q4SGZ9_TETNG EETSRQ-------SAEAADDDDSTSEVGEV Q05BL7_MOUSE Q05BL7_MOUSE EETPR--------PLEELETELVLQMKVKY A7J992_HUMAN A7J992_HUMAN EETPR--------PSEEIENGSSSSDEGEV PHIP_HUMAN PHIP_HUMAN EETPR--------PSEEIENGSSSSDEGEV PHIP_MOUSE PHIP_MOUSE EETPR--------PLEELENGTSSSDEGEV Q05CQ5_MOUSE Q05CQ5_MOUSE EETPR--------PLEELENGTSSSDEGEV BRWD3_HUMAN BRWD3_HUMAN EHNSQASCQ----NSGVQEDSDSSSEEDET BRWD3_MOUSE BRWD3_MOUSE EHNSQASSQ----TSGVQEDSDSSSEEDET Q6NSN0_DANRE Q6NSN0_DANRE TRRRSGSVQSFSRNEETEVESESEAEQEED Q4S8S0_TETNG Q4S8S0_TETNG RRGTRSRNSRNRLNSGSRMDSDSDGEADEQ MATCH . : CONSENSUS E?????????????????????S?????E?

Q4SGZ9_TETNG Q4SGZ9_TETNG EIRQINGHSSEEEKEDEEKEPWPDDHSSSS Q05BL7_MOUSE Q05BL7_MOUSE LLSVVGLLRKRSE---------HGT-VMAA A7J992_HUMAN A7J992_HUMAN -VAVSGGTSEEEERA------WHSD-GSSS PHIP_HUMAN PHIP_HUMAN -VAVSGGTSEEEERA------WHSD-GSSS PHIP_MOUSE PHIP_MOUSE -LAVSGGTSEEEERA------WHSD-GSSS Q05CQ5_MOUSE Q05CQ5_MOUSE -LAVSGGTSEEEERA------WHSD-GSSS BRWD3_HUMAN BRWD3_HUMAN -VGTSDASVEDPVVE------WQSE-SSSS BRWD3_MOUSE BRWD3_MOUSE -VGTSDASVEDPVVE------WQSE-SSSS Q6NSN0_DANRE Q6NSN0_DANRE QNENSDGTSEGETQ-------WEND-SSSS Q4S8S0_TETNG Q4S8S0_TETNG -VEQSEASSDGEAQ-------WQSE-SSSS MATCH . . :: CONSENSUS ????S????????????????W?????SSS

Q4SGZ9_TETNG Q4SGZ9_TETNG DYSSDYSDWTADAGINLEPPKKSVK--VKK Q05BL7_MOUSE Q05BL7_MOUSE PVTTPVIILIGQQMLELTCSHQ------RK A7J992_HUMAN A7J992_HUMAN DYSSDYSDWTADAGINLQPPKKVPKNKTKK PHIP_HUMAN PHIP_HUMAN DYSSDYSDWTADAGINLQPPKKVPKNKTKK PHIP_MOUSE PHIP_MOUSE DYSSDYSDWTADAGINLQPPKKVPKHKTKK Q05CQ5_MOUSE Q05CQ5_MOUSE DYSSDYSDWTADAGINLQPPKKVPKHKTKK BRWD3_HUMAN BRWD3_HUMAN DSSSEYSDWTADAGINLQPPKRQTRQTTRK BRWD3_MOUSE BRWD3_MOUSE DSSSEYSDWIADAGINLQPPKRQTRQATQK Q6NSN0_DANRE Q6NSN0_DANRE DSSSEYSDWTADAGINLQPPKRTTRRPARV Q4S8S0_TETNG Q4S8S0_TETNG DSSSDYSDWTADAGINLQPPKRSSRRPAQP MATCH :: .: ::* .:: : CONSENSUS D?SS?YSDWTADAGINLQPPK????????K

Q4SGZ9_TETNG Q4SGZ9_TETNG KNSSSDEGGEKKRDGKKERKKEKADKD--- Q05BL7_MOUSE Q05BL7_MOUSE FLS--------------------------- A7J992_HUMAN A7J992_HUMAN AESSSDEEEESEKQKQKQIKKEKKKVNEEK PHIP_HUMAN PHIP_HUMAN AESSSDEEEESEKQKQKQIKKEKKKVNEEK PHIP_MOUSE PHIP_MOUSE PESSSDEEEESENQKQKHIKKERKKANEEK Q05CQ5_MOUSE Q05CQ5_MOUSE PESSSDEEEESENQKQKHIKKERKKANEEK BRWD3_HUMAN BRWD3_HUMAN ICSSSDEENLKS------------------ BRWD3_MOUSE BRWD3_MOUSE IYSSSEDENLK------------------- Q6NSN0_DANRE Q6NSN0_DANRE AVSSSSEDEEGTGQGEGEAAQTTK------ Q4S8S0_TETNG Q4S8S0_TETNG QGYSSSEEEEGDNKTKEAKK---------- MATCH CONSENSUS ??SSS?E???????????????????????

Q4SGZ9_TETNG Q4SGZ9_TETNG ---HSIPKKKPKEKSKV------ELQEQGL Q05BL7_MOUSE Q05BL7_MOUSE ---IKPRNQKVVQMKKK------------- A7J992_HUMAN A7J992_HUMAN DGPISPKKKKPKERKQK-RLAVGELTENGL PHIP_HUMAN PHIP_HUMAN DGPISPKKKKPKERKQK-RLAVGELTENGL PHIP_MOUSE PHIP_MOUSE DGPTSPKKKKPKERKQK-RLAVGELTENGL Q05CQ5_MOUSE Q05CQ5_MOUSE DGPTSPKKKKPKEKKKK------------- BRWD3_HUMAN BRWD3_HUMAN ---LEERQKKPKQTRKK---KGGLVSIAGE BRWD3_MOUSE BRWD3_MOUSE ---LEDRQKKPKQTKKK---KGGLVSMAGE Q6NSN0_DANRE Q6NSN0_DANRE ---QAEKKKKPKQRSVP----AGEL----- Q4S8S0_TETNG Q4S8S0_TETNG ---NEEKKKKSKETKQRPTSSLGEL----- MATCH ::* : CONSENSUS ????????KKPK??????????????????

Q4SGZ9_TETNG Q4SGZ9_TETNG TLEEWLPSAWITDTVPRRSPYIPQMGDEVR Q05BL7_MOUSE Q05BL7_MOUSE ------------------------------ A7J992_HUMAN A7J992_HUMAN TLEEWLPSTWITDTIPRRCPFVPQMGDEVY PHIP_HUMAN PHIP_HUMAN TLEEWLPSTWITDTIPRRCPFVPQMGDEVY PHIP_MOUSE PHIP_MOUSE TLEEWLPSAWITDTLPRRCPFVPQMGDEVY Q05CQ5_MOUSE Q05CQ5_MOUSE ------------------------------ BRWD3_HUMAN BRWD3_HUMAN PNEEWFAPQWILDTIPRRSPFVPQMGDELI BRWD3_MOUSE BRWD3_MOUSE PNEEWLAPQWILDTIPRRSPFVPQMGDELI Q6NSN0_DANRE Q6NSN0_DANRE --EEWLPPSWIMETIPRRSPFVPQMGDELI Q4S8S0_TETNG Q4S8S0_TETNG NPEEWLPPSWIMETVPRCSPFVPQMGDELI MATCH CONSENSUS ??EEW????WI??T?PR??P??PQMGDE??

Q4SGZ9_TETNG Q4SGZ9_TETNG TFF--FTVVVSLMAEHAFVCTKTRLSVLFF Q05BL7_MOUSE Q05BL7_MOUSE -----------------------------N A7J992_HUMAN A7J992_HUMAN YFRQGHEAYVEMARKNKIYSINPKKQPWHK PHIP_HUMAN PHIP_HUMAN YFRQGHEAYVEMARKNKIYSINPKKQPWHK PHIP_MOUSE PHIP_MOUSE YFRQGHEAYVEMARKNKIYSINPKKQPWHK Q05CQ5_MOUSE Q05CQ5_MOUSE ------------------------------ BRWD3_HUMAN BRWD3_HUMAN YFRQGHEAYVRAVRKSKIYSVNLQKQPWNK BRWD3_MOUSE BRWD3_MOUSE YFRQGHEAYVRAVRKSKIYSVNLQKQPWNK Q6NSN0_DANRE Q6NSN0_DANRE YFRQGHQAYVRAVSRAKAYSINPQKQPWNR Q4S8S0_TETNG Q4S8S0_TETNG YFKQGHQAYARAVRRAKAYSINPQKQPWNR MATCH CONSENSUS ?F????????????????????????????

Q4SGZ9_TETNG Q4SGZ9_TETNG CGTQEQELMKIVGIKYEVGLPTLCCLKLAF Q05BL7_MOUSE Q05BL7_MOUSE LKTRSKNILK-------------------- A7J992_HUMAN A7J992_HUMAN MELREQELMKIVGIKYEVGLPTLCCLKLAF PHIP_HUMAN PHIP_HUMAN MELREQELMKIVGIKYEVGLPTLCCLKLAF PHIP_MOUSE PHIP_MOUSE MELREQELMKIVGIKYEVGLPTLCCLKLAF Q05CQ5_MOUSE Q05CQ5_MOUSE ------------------------------ BRWD3_HUMAN BRWD3_HUMAN MDLREQEFVKIVGIKYEVGPPTLCCLKLAF BRWD3_MOUSE BRWD3_MOUSE MDLREQEFVKIVGIKYEIGPPTLCCLKLAF Q6NSN0_DANRE Q6NSN0_DANRE LNLRDQESVKVVGIKYEVGPPTLCCLKLAI Q4S8S0_TETNG Q4S8S0_TETNG LNLRDQESVKVVGIKYEVGPPTLCCLKLAF MATCH CONSENSUS ???R?QE??K?VGIKYE?G?PTLCCLKLA?

Q4SGZ9_TETNG Q4SGZ9_TETNG LDPDTGKLTGGSFSMKYHDMPDVIDFLVLR Q05BL7_MOUSE Q05BL7_MOUSE ------------------------------ A7J992_HUMAN A7J992_HUMAN LDPDTGKLTGGSFTMKYHDMPDVIDFLVLR PHIP_HUMAN PHIP_HUMAN LDPDTGKLTGGSFTMKYHDMPDVIDFLVLR PHIP_MOUSE PHIP_MOUSE LDPDTGKLTGGSFTMKYHDMPDVIDFLVLR Q05CQ5_MOUSE Q05CQ5_MOUSE ------------------------------ BRWD3_HUMAN BRWD3_HUMAN LDPISGKMTGESFSIKYHDMPDVIDFLVLH BRWD3_MOUSE BRWD3_MOUSE LDPISGKMTGESFSIKYHDMPDVIDFLVLH Q6NSN0_DANRE Q6NSN0_DANRE LDLTSGKMTNESFSLKYHDMPDVIDFLVLQ Q4S8S0_TETNG Q4S8S0_TETNG LDPVSGKMTNESFSLKYHDMPDVIDFLVLQ MATCH CONSENSUS LD???GK?T??SF??KYHDMPDVIDFLVL?

Q4SGZ9_TETNG Q4SGZ9_TETNG QQFDNARRRQWSIGDRFRSVIDDAWWFGTI Q05BL7_MOUSE Q05BL7_MOUSE ------------------------------ A7J992_HUMAN A7J992_HUMAN QQFDDAKYRRWNIGDRFRSVIDDAWWFGTI PHIP_HUMAN PHIP_HUMAN QQFDDAKYRRWNIGDRFRSVIDDAWWFGTI PHIP_MOUSE PHIP_MOUSE QQFDDAKYRPWNIGDRFRSVIDDAWWFGTI Q05CQ5_MOUSE Q05CQ5_MOUSE ------------------------------ BRWD3_HUMAN BRWD3_HUMAN QFYNEAKERNWQIGDRFRSIIDDAWWFGTV BRWD3_MOUSE BRWD3_MOUSE QFYNEAKERNWQIGDRFRSIIDDAWWFGTV Q6NSN0_DANRE Q6NSN0_DANRE QFYNEAKERNWQPGQRFRSIIDDAWWFGSL Q4S8S0_TETNG Q4S8S0_TETNG QFYNEAKEHNWQPGMRFRSIIDDAWWFGLV MATCH CONSENSUS Q????A????W??G?RFRS?IDDAWWFG??

Q4SGZ9_TETNG Q4SGZ9_TETNG ESQEPYQPQYPDSLFLCYNVCWDNGDTEKM Q05BL7_MOUSE Q05BL7_MOUSE ------------------------------ A7J992_HUMAN A7J992_HUMAN ESQEPLQLEYPDSLFQCYNVCWDNGDTEKM PHIP_HUMAN PHIP_HUMAN ESQEPLQLEYPDSLFQCYNVCWDNGDTEKM PHIP_MOUSE PHIP_MOUSE ESQEPLQPEYPDSLFQCYNVCWDNGDTEKM Q05CQ5_MOUSE Q05CQ5_MOUSE ------------------------------ BRWD3_HUMAN BRWD3_HUMAN ESQQPFQPEYPDSSFQCYSVHWDNNEREKM BRWD3_MOUSE BRWD3_MOUSE ESQQPFQPEYPDSSFQCYSVHWDNNEREKM Q6NSN0_DANRE Q6NSN0_DANRE ECQEPFESEYPDSLFQCYIVRWDNGEREKM Q4S8S0_TETNG Q4S8S0_TETNG EDQEPLQPEYPDSLFQCFAVKWDNGECEKM MATCH CONSENSUS E?Q?P????YPDS?F?C??V?WDN???EKM

Q4SGZ9_TETNG Q4SGZ9_TETNG SPWDMEPVPDDATFPDELGTSVPLTEDEQK Q05BL7_MOUSE Q05BL7_MOUSE ------------------------------ A7J992_HUMAN A7J992_HUMAN SPWDMELIPNNAVFPEELGTSVPLTDGECR PHIP_HUMAN PHIP_HUMAN SPWDMELIPNNAVFPEELGTSVPLTDGECR PHIP_MOUSE PHIP_MOUSE SPWDMELIPNNAVFPEELGTSVPLTDVECR Q05CQ5_MOUSE Q05CQ5_MOUSE ------------------------------ BRWD3_HUMAN BRWD3_HUMAN SPWDMEPIPEGTAFPDEVGAGVPVSQEELT BRWD3_MOUSE BRWD3_MOUSE SPWDMEPIPDGTAFPDEVGAGIPVSQEELT Q6NSN0_DANRE Q6NSN0_DANRE SPWDIEPIPEEAPLPEEDGDSVPVTEDELQ Q4S8S0_TETNG Q4S8S0_TETNG SPWDMEPIPEEAALPEQVGDGVEVAEEEMK MATCH CONSENSUS SPWD?E??P?????P???G????????E??

Q4SGZ9_TETNG Q4SGZ9_TETNG ELLYVPLEGEWGCQSRAEECERIIKAIDQL Q05BL7_MOUSE Q05BL7_MOUSE ------------------------------ A7J992_HUMAN A7J992_HUMAN SLIYKPLDGEWGTNPRDEECERIVAGINQL PHIP_HUMAN PHIP_HUMAN SLIYKPLDGEWGTNPRDEECERIVAGINQL PHIP_MOUSE PHIP_MOUSE SLIYKPLDGEWGANPRDEECERIVGGINQL Q05CQ5_MOUSE Q05CQ5_MOUSE ------------------------------ BRWD3_HUMAN BRWD3_HUMAN ALLYKPQEGEWGAHSRDEECERVIQGINHL BRWD3_MOUSE BRWD3_MOUSE ALLYKPQEGEWGAHSRDEECERVIQGINNL Q6NSN0_DANRE Q6NSN0_DANRE ALLYSPQEGEWGLHTRDEECERVITAIDQL Q4S8S0_TETNG Q4S8S0_TETNG ALLYRPQEGEWGAHTRDEECERVICGIEQL MATCH CONSENSUS ?L?Y?P??GEWG???R?EECER????I??L

Q4SGZ9_TETNG Q4SGZ9_TETNG CTLDVAAPFAFPVDLQAYPTYCTVVAYVTD Q05BL7_MOUSE Q05BL7_MOUSE ------------------------------ A7J992_HUMAN A7J992_HUMAN MTLDIASAFVAPVDLQAYPMYCTVVAYPTD PHIP_HUMAN PHIP_HUMAN MTLDIASAFVAPVDLQAYPMYCTVVAYPTD PHIP_MOUSE PHIP_MOUSE MTLDIASAFVAPVDLQAYPMYCTVVAYPTD Q05CQ5_MOUSE Q05CQ5_MOUSE ------------------------------ BRWD3_HUMAN BRWD3_HUMAN LSLDFASPFAVPVDLSAYPLYCTVVAYPTD BRWD3_MOUSE BRWD3_MOUSE LSLDFASPFAVPVDLSAYPLYCTVVAYPTD Q6NSN0_DANRE Q6NSN0_DANRE LTLDVAKAFSNPVNLREYPLYCTVVAYLTD Q4S8S0_TETNG Q4S8S0_TETNG FTLEVAKAFASPVNLQDYPLYCAVVAYPTD MATCH CONSENSUS ??L??A??F??PV?L??YP?YC?VVAY?TD

Q4SGZ9_TETNG Q4SGZ9_TETNG LSTIRQRLVNRFYRRLSSLMWEVRYIEHNT Q05BL7_MOUSE Q05BL7_MOUSE ------------------------------ A7J992_HUMAN A7J992_HUMAN LSTIKQRLENRFYRRVSSLMWEVRYIEHNT PHIP_HUMAN PHIP_HUMAN LSTIKQRLENRFYRRVSSLMWEVRYIEHNT PHIP_MOUSE PHIP_MOUSE LSTIKQRLENRFYRRFSSLMWEVRYIEHNT Q05CQ5_MOUSE Q05CQ5_MOUSE ------------------------------ BRWD3_HUMAN BRWD3_HUMAN LNTIRRRLENRFYRRISALMWEVRYIEHNA BRWD3_MOUSE BRWD3_MOUSE LNTIKQRLENRFYRRISALMWEVRYIEHNA Q6NSN0_DANRE Q6NSN0_DANRE LSTIRTRLVHRFYRRISALMWEVRYIEHNA Q4S8S0_TETNG Q4S8S0_TETNG LSTIRKRLENRFYRRISALMWEVRYIEHNA MATCH CONSENSUS L?TI??RL??RFYRR?S?LMWEVRYIEHN?

Q4SGZ9_TETNG Q4SGZ9_TETNG QTFNEPRSFIVTTAKFVSDLMLQFIKDQSL Q05BL7_MOUSE Q05BL7_MOUSE ------------------------------ A7J992_HUMAN A7J992_HUMAN RTFNEPGSPIVKSAKFVTDLLLHFIKDQTC PHIP_HUMAN PHIP_HUMAN RTFNEPGSPIVKSAKFVTDLLLHFIKDQTC PHIP_MOUSE PHIP_MOUSE RTFNEPGSPIVKSAKFVTDLLLHFIKDQTC Q05CQ5_MOUSE Q05CQ5_MOUSE ------------------------------ BRWD3_HUMAN BRWD3_HUMAN RTFNEPDSPIVKAAKIVTDVLLRFIGDQSC BRWD3_MOUSE BRWD3_MOUSE RTFNEPDSPIVKAAKIVTDVLLRFIGDQSC Q6NSN0_DANRE Q6NSN0_DANRE RTFNEPQSPIVTAAKTVSDVLLRFIRDQNC Q4S8S0_TETNG Q4S8S0_TETNG RTFNEPQSPIVATAKVVTDVLLRYIGDQSC MATCH CONSENSUS ?TFNEP?S?IV??AK?V?D??L??I?DQ??

Q4SGZ9_TETNG Q4SGZ9_TETNG TDLMPLYKTMKKATFSDSEDEEEADDDEDE Q05BL7_MOUSE Q05BL7_MOUSE ------------------------------ A7J992_HUMAN A7J992_HUMAN YNIIPLYNSMKKKVLSDSEDEE-------K PHIP_HUMAN PHIP_HUMAN YNIIPLYNSMKKKVLSDSEDEE-------K PHIP_MOUSE PHIP_MOUSE YNIIPLYNSMKKKVLSDSEEEE-------K Q05CQ5_MOUSE Q05CQ5_MOUSE ------------------------------ BRWD3_HUMAN BRWD3_HUMAN TDILDTYNKIKAEERNSTDAEEDT-EIVDL BRWD3_MOUSE BRWD3_MOUSE SDILDTYNKIKAEDPDSSDLEEDS-EMVDL Q6NSN0_DANRE Q6NSN0_DANRE TDILDLYNKMKSEFSSEEDEEE----TVDV Q4S8S0_TETNG Q4S8S0_TETNG TDILDLYHKLKADISSGEEAKV---SVSLL MATCH CONSENSUS ??????Y???K???????????????????

Q4SGZ9_TETNG Q4SGZ9_TETNG DSNTPGTSTRNHRNPQPMQRRLRTRPHSYN Q05BL7_MOUSE Q05BL7_MOUSE ---------------RKEKKQMKKK----- A7J992_HUMAN A7J992_HUMAN DADVPGTSTR-KRKDHQPRRRLRNRAQSYD PHIP_HUMAN PHIP_HUMAN DADVPGTSTR-KRKDHQPRRRLRNRAQSYD PHIP_MOUSE PHIP_MOUSE DADVPGTSTR-KRKDHQPRRRLRNRAQSYD Q05CQ5_MOUSE Q05CQ5_MOUSE ------------------------------ BRWD3_HUMAN BRWD3_HUMAN DSDGPGTSSG-----RRVKCRGRRQSLKCN BRWD3_MOUSE BRWD3_MOUSE DSDGPGTSSG-----RRAKCRGRRQSLKCN Q6NSN0_DANRE Q6NSN0_DANRE DSDTPGTSTG----QRRSNSTPQKRGVVLD Q4S8S0_TETNG Q4S8S0_TETNG PPASAYLFSNVPKNTHLSNQNSNKRGAALE MATCH CONSENSUS ??????????????????????????????

Q4SGZ9_TETNG Q4SGZ9_TETNG PQAWRGRCKELLDLIFQCEDSEPFREPVDL Q05BL7_MOUSE Q05BL7_MOUSE ------------------------------ A7J992_HUMAN A7J992_HUMAN IQAWKKQCEELLNLIFQCEDSEPFRQPVDL PHIP_HUMAN PHIP_HUMAN IQAWKKQCEELLNLIFQCEDSEPFRQPVDL PHIP_MOUSE PHIP_MOUSE IQAWKKQCQELLNLIFQCEDSEPFRQPVDL Q05CQ5_MOUSE Q05CQ5_MOUSE ------------------------------ BRWD3_HUMAN BRWD3_HUMAN PDAWKKQCKELLSLIYEREDSEPFRQPADL BRWD3_MOUSE BRWD3_MOUSE PDAWKKQCEELLSLIYEREDSEPFRQPADP Q6NSN0_DANRE Q6NSN0_DANRE INAWHKQCKDLVRRMIVSSDSEPFRQPVDL Q4S8S0_TETNG Q4S8S0_TETNG VKAWRGRCRELLRRMVASPDSQPFRQPVDL MATCH CONSENSUS ??AW???C??L????????DS?PFR?P?D?

Q4SGZ9_TETNG Q4SGZ9_TETNG QEYP-------------------------D Q05BL7_MOUSE Q05BL7_MOUSE ------------------------------ A7J992_HUMAN A7J992_HUMAN LEYP-------------------------D PHIP_HUMAN PHIP_HUMAN LEYP-------------------------D PHIP_MOUSE PHIP_MOUSE LEYP-------------------------D Q05CQ5_MOUSE Q05CQ5_MOUSE ------------------------------ BRWD3_HUMAN BRWD3_HUMAN LSYPGHQEQEGESSESVVPERQQDSSLSED BRWD3_MOUSE BRWD3_MOUSE QSYPVQQQQEGESSQSVPPDR-QDPSLSED Q6NSN0_DANRE Q6NSN0_DANRE FTYP-------------------------D Q4S8S0_TETNG Q4S8S0_TETNG FEYP-------------------------D MATCH CONSENSUS ??YP?????????????????????????D

Q4SGZ9_TETNG Q4SGZ9_TETNG YLEIVESPMDFGTVLSTLTEGKYQSPIELC Q05BL7_MOUSE Q05BL7_MOUSE ------------------------------ A7J992_HUMAN A7J992_HUMAN YRDIIDTPMDFATVRETLEAGNYESPMELC PHIP_HUMAN PHIP_HUMAN YRDIIDTPMDFATVRETLEAGNYESPMELC PHIP_MOUSE PHIP_MOUSE YRDIIDTPMDFATVRETLEAGNYESPMELC Q05CQ5_MOUSE Q05CQ5_MOUSE ------------------------------ BRWD3_HUMAN BRWD3_HUMAN YQDVIDTPVDFSTVKETLEAGNYGSPLEFY BRWD3_MOUSE BRWD3_MOUSE YQDGIDTPMDFSTVKETLESGNYDSPLEFY Q6NSN0_DANRE Q6NSN0_DANRE YRDIIDTPMDLGTVSETLTGGNYENPIEFA Q4S8S0_TETNG Q4S8S0_TETNG YRDIIDTPMDLGTVSETLYEGNYENPMEFA MATCH CONSENSUS Y??????P?D??TV??TL??G?Y??P?E??

Q4SGZ9_TETNG Q4SGZ9_TETNG KDVRLIFSNSKAYTPSKKSRIYSMSLRLSA Q05BL7_MOUSE Q05BL7_MOUSE ------------------------------ A7J992_HUMAN A7J992_HUMAN KDVRLIFSNSKAYTPSKRSRIYSMSLRLSA PHIP_HUMAN PHIP_HUMAN KDVRLIFSNSKAYTPSKRSRIYSMSLRLSA PHIP_MOUSE PHIP_MOUSE KDVRLIFSNFKAYTPSKRSRIYSMSLRLSA Q05CQ5_MOUSE Q05CQ5_MOUSE ------------------------------ BRWD3_HUMAN BRWD3_HUMAN KDVRQIFNNSKAYTSNKKSRIYSMMLRLSA BRWD3_MOUSE BRWD3_MOUSE KDVRQIFSNSKAYTSNKKSRIYSMTLRLSA Q6NSN0_DANRE Q6NSN0_DANRE KDVRLIFSNSKAYTPNKKSRIYSMTLSLSA Q4S8S0_TETNG Q4S8S0_TETNG KDIRLIFSNSKAYTPNKKSQIYAMTLSLSA MATCH CONSENSUS KD?R?IF?N?KAYT??K?S?IY?M?L?LSA

Q4SGZ9_TETNG Q4SGZ9_TETNG LFEEHVGPILADYRAIHGLTGKLSRQSTDR Q05BL7_MOUSE Q05BL7_MOUSE -MDQH------------------------- A7J992_HUMAN A7J992_HUMAN FFEEHISSVLSDYKSALRF----------- PHIP_HUMAN PHIP_HUMAN FFEEHISSVLSDYKSALRF----------- PHIP_MOUSE PHIP_MOUSE FFEEHISSVLSDYKSALRF----------- Q05CQ5_MOUSE Q05CQ5_MOUSE ------------------------------ BRWD3_HUMAN BRWD3_HUMAN LFESHIKNIISEYKSAIQS----------- BRWD3_MOUSE BRWD3_MOUSE LFENHIKNIISDYKSAIQS----------- Q6NSN0_DANRE Q6NSN0_DANRE FFENQIIPIISDYKSAVQN----------- Q4S8S0_TETNG Q4S8S0_TETNG FFEKSIISIISDYKSAIQN----------- MATCH CONSENSUS ?FE?????????Y?????????????????

Q4SGZ9_TETNG Q4SGZ9_TETNG QTRHTTDRQTRHAMKRRRRRSESPASSTAS Q05BL7_MOUSE Q05BL7_MOUSE ---HQRKK---------------------- A7J992_HUMAN A7J992_HUMAN ---HKRNTIT--KRRKKRNRSSSVSSSAAS PHIP_HUMAN PHIP_HUMAN ---HKRNTIT--KRRKKRNRSSSVSSSAAS PHIP_MOUSE PHIP_MOUSE ---HKRNTIS--KKRKKRNRSSSLSSSAAS Q05CQ5_MOUSE Q05CQ5_MOUSE ------------------------------ BRWD3_HUMAN BRWD3_HUMAN ---QKRRRPR--YRKRLRSSSSSLSSSGAP BRWD3_MOUSE BRWD3_MOUSE ---QKRRRPR--YRKRLRSSSSSLSSSRAP Q6NSN0_DANRE Q6NSN0_DANRE ---QRRSQQRLMCSKRLQSSSPN------- Q4S8S0_TETNG Q4S8S0_TETNG ---ERRTRQRLSYRDRLQNGGSSPPVSPSP MATCH CONSENSUS ?????R????????????????????????

Q4SGZ9_TETNG Q4SGZ9_TETNG SPERKRRMSSRVLTKKESSPAPSRPPSLRQ Q05BL7_MOUSE Q05BL7_MOUSE SPKKKK------------------------ A7J992_HUMAN A7J992_HUMAN SPERKKRILKPQLKSESSTSAFSTPTR--- PHIP_HUMAN PHIP_HUMAN SPERKKRILKPQLKSESSTSAFSTPTR--- PHIP_MOUSE PHIP_MOUSE SPERKKRILKPQLKSEVSTSPFSIPTR--- Q05CQ5_MOUSE Q05CQ5_MOUSE ------------------------------ BRWD3_HUMAN BRWD3_HUMAN SPKGKQKQMKLQPKNDQNTSVSHARTSSPF BRWD3_MOUSE BRWD3_MOUSE SPKGKQKQMKLQPKNDQNTSVAYARTSSPF Q6NSN0_DANRE Q6NSN0_DANRE SPKGKQKSGKKTLQMSAK-----ARTR--- Q4S8S0_TETNG Q4S8S0_TETNG SSEKQQR----------------------- MATCH CONSENSUS SP??K?????????????????????????

Q4SGZ9_TETNG Q4SGZ9_TETNG SIPTKQAPQLVNGKAEALAGGRTRSAARNS Q05BL7_MOUSE Q05BL7_MOUSE ------------------------------ A7J992_HUMAN A7J992_HUMAN SIPPRHNAAQINGKTESSSVVRTRSNRVVV PHIP_HUMAN PHIP_HUMAN SIPPRHNAAQINGKTESSSVVRTRSNRVVV PHIP_MOUSE PHIP_MOUSE SVLPRHNAAQMNGKPESSSVVRTRSNRVAV Q05CQ5_MOUSE Q05CQ5_MOUSE ------------------------------ BRWD3_HUMAN BRWD3_HUMAN SSPVSDAAEGLSLYLLDDEPDGPFSSSSFG BRWD3_MOUSE BRWD3_MOUSE SSPVSDAAEGVSLYLLDDEGDGPFSPSSFS Q6NSN0_DANRE Q6NSN0_DANRE KSSQDSNVAQVD---EDSQPSSSSSSSSSS Q4S8S0_TETNG Q4S8S0_TETNG ------------------------------ MATCH CONSENSUS ??????????????????????????????

Q4SGZ9_TETNG Q4SGZ9_TETNG THTPPVASSTQSATSNTQTTAGSATFACRF Q05BL7_MOUSE Q05BL7_MOUSE ------------------------------ A7J992_HUMAN A7J992_HUMAN DPVVTEQPSTSSAAKTFITKANASAIPGKT PHIP_HUMAN PHIP_HUMAN DPVVTEQPSTSSAAKTFITKANASAIPGKT PHIP_MOUSE PHIP_MOUSE DPVVTEQPSTSSATKAFVSKTNTSAMPGKA Q05CQ5_MOUSE Q05CQ5_MOUSE ------------------------------ BRWD3_HUMAN BRWD3_HUMAN GYSRSGNSHDPGKAKSFRNRV--LPVKQDH BRWD3_MOUSE BRWD3_MOUSE GYSRSGNSHDPGKAKSFRNRV--LPAKQDH Q6NSN0_DANRE Q6NSN0_DANRE SSSSSFSSEQAGANRVTRSQVTSSKSSGVF Q4S8S0_TETNG Q4S8S0_TETNG ------------------------------ MATCH CONSENSUS ??????????????????????????????

Q4SGZ9_TETNG Q4SGZ9_TETNG MFTATLRVNKRIIVTFHFCSESTRLLRGHS Q05BL7_MOUSE Q05BL7_MOUSE ------------------------------ A7J992_HUMAN A7J992_HUMAN ILENSVKHSKALNTLSS--PGQSSFSHGTR PHIP_HUMAN PHIP_HUMAN ILENSVKHSKALNTLSS--PGQSSFSHGTR PHIP_MOUSE PHIP_MOUSE MLENSVRHSKALSTLSS--PDPLTFSHATK Q05CQ5_MOUSE Q05CQ5_MOUSE ------------------------------ BRWD3_HUMAN BRWD3_HUMAN SLDGPLTNGDGREPRTGIKRKLLSASEEDE BRWD3_MOUSE BRWD3_MOUSE SLDGPLTNVDGREPRTGAKRKLLSASEEDE Q6NSN0_DANRE Q6NSN0_DANRE LPNGGRSSRRRRAVLTE------------- Q4S8S0_TETNG Q4S8S0_TETNG ------------------------------ MATCH CONSENSUS ??????????????????????????????

Q4SGZ9_TETNG Q4SGZ9_TETNG SNSTPPAAEKVTP-SPTMETNSGGSTRRKL Q05BL7_MOUSE Q05BL7_MOUSE ------------------------------ A7J992_HUMAN A7J992_HUMAN NNSAKENMEKEKPVKRKMKSSVLPKASTLS PHIP_HUMAN PHIP_HUMAN NNSAKENMEKEKPVKRKMKSSVLPKASTLS PHIP_MOUSE PHIP_MOUSE NNSAKENMEKEKPVKRKMKSSVFSKASPLP Q05CQ5_MOUSE Q05CQ5_MOUSE ------------------------------ BRWD3_HUMAN BRWD3_HUMAN NMGGEDKEKKETKEKSHLSTSESGELGSSL BRWD3_MOUSE BRWD3_MOUSE SMGGEEKEMKETKEQVHLSSSESGELGSSL Q6NSN0_DANRE Q6NSN0_DANRE --------EGEVSECESTSSSSSSTSASSS Q4S8S0_TETNG Q4S8S0_TETNG ------------------------------ MATCH CONSENSUS ??????????????????????????????

Q4SGZ9_TETNG Q4SGZ9_TETNG KPPVRHSPGS-PDSPSSHNTVHLNGHSSH- Q05BL7_MOUSE Q05BL7_MOUSE ------------------------------ A7J992_HUMAN A7J992_HUMAN KSSAVIEQGDCKNNALVPGTIQVNGHGGQP PHIP_HUMAN PHIP_HUMAN KSSAVIEQGDCKNNALVPGTIQVNGHGGQP PHIP_MOUSE PHIP_MOUSE KSAAVIEQGECKNNVLIPGTIQVNGHGGQP Q05CQ5_MOUSE Q05CQ5_MOUSE ------------------------------ BRWD3_HUMAN BRWD3_HUMAN SSESTCGSDSDSESTSRTDQDYVDGDHDY- BRWD3_MOUSE BRWD3_MOUSE SSESTSGSDSDSESTSRTDQDYVDGDHDY- Q6NSN0_DANRE Q6NSN0_DANRE SSATSSSSSESDDSSAEVSGFADGGDHDYS Q4S8S0_TETNG Q4S8S0_TETNG ------------------------------ MATCH CONSENSUS ??????????????????????????????

Q4SGZ9_TETNG Q4SGZ9_TETNG VTLGEGKKGRKSRVDAPASPPEATTPGSPS Q05BL7_MOUSE Q05BL7_MOUSE ------------------------------ A7J992_HUMAN A7J992_HUMAN SKLVKRGPGRKPKVEVNTNS-----GEIIH PHIP_HUMAN PHIP_HUMAN SKLVKRGPGRKPKVEVNTNS-----GEIIH PHIP_MOUSE PHIP_MOUSE SKLVKRGPGRKPKVEVNTSS-----GEVTH Q05CQ5_MOUSE Q05CQ5_MOUSE ------------------------------ BRWD3_HUMAN BRWD3_HUMAN SKFIQTRPKRKLRKQHGNGK-----RNWKT BRWD3_MOUSE BRWD3_MOUSE SKFIQTRPKRKLRKQHTNGK-----RNWKT Q6NSN0_DANRE Q6NSN0_DANRE KAPQHKQKGKAPAPPPPSPPPPPPAPTIDN Q4S8S0_TETNG Q4S8S0_TETNG ------------------------------ MATCH CONSENSUS ??????????????????????????????

Q4SGZ9_TETNG Q4SGZ9_TETNG RPRGRPPGKKRGRKSKQEMEELRGSSIPDD Q05BL7_MOUSE Q05BL7_MOUSE ------------------------------ A7J992_HUMAN A7J992_HUMAN KKRGRKPKKLQYAKP-EDLEQNNVHPIRDE PHIP_HUMAN PHIP_HUMAN KKRGRKPKKLQYAKP-EDLEQNNVHPIRDE PHIP_MOUSE PHIP_MOUSE KKRGRKPKNLQCAKQ-ENSEQNNMHPIRAD Q05CQ5_MOUSE Q05CQ5_MOUSE ------------------------------ BRWD3_HUMAN BRWD3_HUMAN RGTGGRGRWGRWGRW-SRGGRGRGGRGRG- BRWD3_MOUSE BRWD3_MOUSE RGTGGRGRWGRWGRW-SRGGRGRGGRGRG- Q6NSN0_DANRE Q6NSN0_DANRE PKRKRKGEEEQSAEP-EKRPRRTSSR---- Q4S8S0_TETNG Q4S8S0_TETNG ------------------------------ MATCH CONSENSUS ??????????????????????????????

Q4SGZ9_TETNG Q4SGZ9_TETNG DLDQSTGDECGPSSAQETAVMSDSGVASPP Q05BL7_MOUSE Q05BL7_MOUSE ------------------------------ A7J992_HUMAN A7J992_HUMAN VLPSSTCNFLSETNNVKEDLLQKKN----- PHIP_HUMAN PHIP_HUMAN VLPSSTCNFLSETNNVKEDLLQKKN----- PHIP_MOUSE PHIP_MOUSE VLPSSTCNFLSETNAVKEDLLQKKS----- Q05CQ5_MOUSE Q05CQ5_MOUSE ------------------------------ BRWD3_HUMAN BRWD3_HUMAN ----------SRGRGGGGTRGRGRG----- BRWD3_MOUSE BRWD3_MOUSE ----------GRGRGGGGGRGRGRG----- Q6NSN0_DANRE Q6NSN0_DANRE ----------EEEEEEEEEEVDDEP----- Q4S8S0_TETNG Q4S8S0_TETNG ------------------------------ MATCH CONSENSUS ??????????????????????????????

Q4SGZ9_TETNG Q4SGZ9_TETNG RRRGRPRTTRTDEAAPPAESPEPSPLRRSS Q05BL7_MOUSE Q05BL7_MOUSE ------------------------------ A7J992_HUMAN A7J992_HUMAN -RGGRKPKRKMKTQKLDADLLVPASVKVLR PHIP_HUMAN PHIP_HUMAN -RGGRKPKRKMKTQKLDADLLVPASVKVLR PHIP_MOUSE PHIP_MOUSE -RGGRKPKRKMKTHNLDSELIVPTNVKVLR Q05CQ5_MOUSE Q05CQ5_MOUSE ------------------------------ BRWD3_HUMAN BRWD3_HUMAN -RGGRGASRGAT------------------ BRWD3_MOUSE BRWD3_MOUSE -RGGRGASRGSS------------------ Q6NSN0_DANRE Q6NSN0_DANRE -EEEEEPDEEEEPEEEEEESDDENVISPSK Q4S8S0_TETNG Q4S8S0_TETNG -SRGRGC----------------------- MATCH CONSENSUS ??????????????????????????????

Q4SGZ9_TETNG Q4SGZ9_TETNG RRTNEEVTPPPQLTQSKSSRKESPKEDAGD Q05BL7_MOUSE Q05BL7_MOUSE ------------------------------ A7J992_HUMAN A7J992_HUMAN RSNRKKIDDPIDEEEEFEELKGSE------ PHIP_HUMAN PHIP_HUMAN RSNRKKIDDPIDEEEEFEELKGSE------ PHIP_MOUSE PHIP_MOUSE RSNRKKTDDPIDEEEEFEELKGSE------ Q05CQ5_MOUSE Q05CQ5_MOUSE ------------------------------ BRWD3_HUMAN BRWD3_HUMAN RAKRARIADD-EFDTMFSGRFSRL------ BRWD3_MOUSE BRWD3_MOUSE RAKRARVADD-EFDTMFSGRFSRL------ Q6NSN0_DANRE Q6NSN0_DANRE RS---------------NQRTPKS------ Q4S8S0_TETNG Q4S8S0_TETNG ------------------------------ MATCH CONSENSUS ??????????????????????????????

Q4SGZ9_TETNG Q4SGZ9_TETNG AAGGSMRTRNQGRRSAWYMEEDSEEEQRQL Q05BL7_MOUSE Q05BL7_MOUSE ------------------------------ A7J992_HUMAN A7J992_HUMAN ---PHMRTRNQGRRTAFYNEDDSEEEQRQL PHIP_HUMAN PHIP_HUMAN ---PHMRTRNQGRRTAFYNEDDSEEEQRQL PHIP_MOUSE PHIP_MOUSE ---PHMRTRNQGRRTAFYNEDDSEEEQRQL Q05CQ5_MOUSE Q05CQ5_MOUSE ------------------------------ BRWD3_HUMAN BRWD3_HUMAN ---PRIKTRNQGRRTVLYNDDSDNDN---F BRWD3_MOUSE BRWD3_MOUSE ---PRIKTRNQGRRTVLYNDDSDNDN---F Q6NSN0_DANRE Q6NSN0_DANRE ---GRVNTRNQGRRTVLYNDDSEEEG---- Q4S8S0_TETNG Q4S8S0_TETNG ---PTVLSK--------FRDEQ-------- MATCH CONSENSUS ??????????????????????????????

Q4SGZ9_TETNG Q4SGZ9_TETNG LFEDSSITFGTSSKGRVRKLTEKAK-ANLI Q05BL7_MOUSE Q05BL7_MOUSE ------------------------------ A7J992_HUMAN A7J992_HUMAN LFEDTSLTFGTSSRGRVRKLTEKAK-ANLI PHIP_HUMAN PHIP_HUMAN LFEDTSLTFGTSSRGRVRKLTEKAK-ANLI PHIP_MOUSE PHIP_MOUSE LFEDTSLTFGTSSRGRVRKLTEKAK-ANLI Q05CQ5_MOUSE Q05CQ5_MOUSE ------------------------------ BRWD3_HUMAN BRWD3_HUMAN VSTEDPLNLGTSRSGRVRKMTEKARVSHLM BRWD3_MOUSE BRWD3_MOUSE VSTEDPLNLGTSRSGRVRKMTEKARVSHLM Q6NSN0_DANRE Q6NSN0_DANRE -PTSDPLNLGMSRSGRVRRMTERARVSHLM Q4S8S0_TETNG Q4S8S0_TETNG ------------------------------ MATCH CONSENSUS ??????????????????????????????

Q4SGZ9_TETNG Q4SGZ9_TETNG GW-- Q05BL7_MOUSE Q05BL7_MOUSE ---- A7J992_HUMAN A7J992_HUMAN GW-- PHIP_HUMAN PHIP_HUMAN GW-- PHIP_MOUSE PHIP_MOUSE GW-- Q05CQ5_MOUSE Q05CQ5_MOUSE ---- BRWD3_HUMAN BRWD3_HUMAN GWNY BRWD3_MOUSE BRWD3_MOUSE GWNY Q6NSN0_DANRE Q6NSN0_DANRE GWTH Q4S8S0_TETNG Q4S8S0_TETNG ---- MATCH CONSENSUS ????


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