Alignment of the gene Family HBG108248 of HOVERGEN

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Threshold: 50% 80% 100%
Size: Bigger Smaller Normal
Isoforms are OFF
Q4SGZ9_TETNG Q4SGZ9_TETNG ------------ELYFLIARFLEAGPCQKAAETLIREVEEKELLPKRLDWTGQEHPGTYE Q05BL7_MOUSE Q05BL7_MOUSE SRERKGLSELRSELYFLIARFLEDGPCQQAAQVLIREVAEKELLPRRTDWTGKEHPRTYQ A7J992_HUMAN A7J992_HUMAN SCERKGLSELRSELYFLIARFLEDGPCQQAAQVLIREVAEKELLPRRTDWTGKEHPRTYQ PHIP_HUMAN PHIP_HUMAN SCERKGLSELRSELYFLIARFLEDGPCQQAAQVLIREVAEKELLPRRTDWTGKEHPRTYQ PHIP_MOUSE PHIP_MOUSE SRERKGLSELRSELYFLIARFLEDGPCQQAAQVLIREVAEKELLPRRTDWTGKEHPRTYQ Q05CQ5_MOUSE Q05CQ5_MOUSE SRERKGLSELRSELYFLIARFLEDGPCQQAAQVLIREVAEKELLPRRTDWTGKEHPRTYQ BRWD3_HUMAN BRWD3_HUMAN --MAAAPTQIEAELYYLIARFLQSGPCNKSAQVLVQELEEHQLIPRRLDWEGKEHRRSFE BRWD3_MOUSE BRWD3_MOUSE --MAAAPTQIEAELYYLIARFLQSGPCNKSAQVLVQELEEHQLIPRRLDWEGKEHRRSFE Q6NSN0_DANRE Q6NSN0_DANRE ------------------------------------------------------------ Q4S8S0_TETNG Q4S8S0_TETNG -----------SELYYLIARFLQSGPCKKAAQILIEELEEYELVPERWSWDGKKYKQTFQ MATCH CONSENSUS ????????????ELY?LIARFL??GPC???AQ?L??E??E??L?P?R?DW?GKEH?????

Q4SGZ9_TETNG Q4SGZ9_TETNG NLVKLYRHVSADHLLQVCSKVCPLLEREVPASVPGLTSLLGAGRQNLLRTSKS------- Q05BL7_MOUSE Q05BL7_MOUSE NLVKYYRHLAPDHLLQICHRLGPLLEQEIPQSVPGVQTLLGAGRQSLLRTNKS------- A7J992_HUMAN A7J992_HUMAN NLVKYYRHLAPDHLLQICHRLGPLLEQEIPQSVPGVQTLLGAGRQSLLRTNKS------- PHIP_HUMAN PHIP_HUMAN NLVKYYRHLAPDHLLQICHRLGPLLEQEIPQSVPGVQTLLGAGRQSLLRTNKS------- PHIP_MOUSE PHIP_MOUSE NLVKYYRHLAPDHLLQICHRLGPLLEQEIPQSVPGVQTLLGAGRQSLLRTNKS------- Q05CQ5_MOUSE Q05CQ5_MOUSE NLVKYYRHLAPDHLLQICHRLGPLLEQEIPQSVPGVQTLLGAGRQSLLRTNKS------- BRWD3_HUMAN BRWD3_HUMAN DLVAANAHIPPDYLLKICERIGPLLDKEIPQSVPGVQTLLGVGRQSLLRDAKD------- BRWD3_MOUSE BRWD3_MOUSE DLVAANAHIPPDYLLKICERIGPLLDKEIPQSVPGVQTLLGVGRQSLLRDAKD------- Q6NSN0_DANRE Q6NSN0_DANRE ------------------------------------------------------------ Q4S8S0_TETNG Q4S8S0_TETNG DWVIVNEHIPADYLLRVCQRIGPLIEKEVPPSVPGVQTLLGLGKQSLLRTSKSKYFLSHL MATCH CONSENSUS ?LV????H???D?LL??C?R?GPLL??E?P?SVPGVQTLLG?GRQSLLR??K????????

Q4SGZ9_TETNG Q4SGZ9_TETNG ----------------------CKHVVWKGSALAALHCGRPPEPPVIYGSPPNIDVDDSD Q05BL7_MOUSE Q05BL7_MOUSE ----------------------CKHVVWKGSALAALHCGRPPESPVNYGSPPSI------ A7J992_HUMAN A7J992_HUMAN ----------------------CKHVVWKGSALAALHCGRPPESPVNYGSPPSI------ PHIP_HUMAN PHIP_HUMAN ----------------------CKHVVWKGSALAALHCGRPPESPVNYGSPPSI------ PHIP_MOUSE PHIP_MOUSE ----------------------CKHVVWKGSALAALHCGRPPESPVNYGSPPSI------ Q05CQ5_MOUSE Q05CQ5_MOUSE ----------------------CKHVVWKGSALAALHCGRPPESPVNYGSPPSI------ BRWD3_HUMAN BRWD3_HUMAN ----------------------CKSTLWNGSAFAALHRGRPPELPVNYVKPPNV------ BRWD3_MOUSE BRWD3_MOUSE ----------------------CKSTLWNGSAFAALHRGRPPELPVNYVKPPNV------ Q6NSN0_DANRE Q6NSN0_DANRE -----------------------------------------------AGGPLS------- Q4S8S0_TETNG Q4S8S0_TETNG HSLGFNINSISTYRLTCFCDLGCIHKVCSGSSIAALHRGRPPEPPVINGGPPNV------ MATCH * . CONSENSUS ??????????????????????CK???W?GSA?AALH?GRPPE?PV?YG?PP????????

Q4SGZ9_TETNG Q4SGZ9_TETNG ETSSILIVVETSFSRRLNGSYRLRQLVPTAVYQHMKMHKRILGHLSSVYCVTFDRTGRRI Q05BL7_MOUSE Q05BL7_MOUSE --------ADTLFSRKLNGKYRLERLVPTAVYQHMKMHKRILGHLSSVYCVTFDRTGRRI A7J992_HUMAN A7J992_HUMAN --------ADTLFSRKLNGKYRLERLVPTAVYQHMKMHKRILGHLSSVYCVTFDRTGRRI PHIP_HUMAN PHIP_HUMAN --------ADTLFSRKLNGKYRLERLVPTAVYQHMKMHKRILGHLSSVYCVTFDRTGRRI PHIP_MOUSE PHIP_MOUSE --------ADTLFSRKLNGKYRLERLVPTAVYQHMKMHKRILGHLSSVYCVTFDRTGRRI Q05CQ5_MOUSE Q05CQ5_MOUSE --------ADTLFSRKLNGKYRLERLVPTAVYQHMKMHKRILGHLSSVYCVTFDRTGRRI BRWD3_HUMAN BRWD3_HUMAN --------VNITSARQLTGCSRFGHIFPSSAYQHIKMHKRILGHLSSVYCVAFDRSGRRI BRWD3_MOUSE BRWD3_MOUSE --------VNITSARQLTGCSRFSHVFPSSAYQHIKMHKRILGHLSSVYCVAFDRSGRRI Q6NSN0_DANRE Q6NSN0_DANRE ------------------------------------------------------------ Q4S8S0_TETNG Q4S8S0_TETNG --------VSTMAARQATGTARFSQVLPSSSYQHMKIHKRILGHLSSVYCVVFDRTGRRI MATCH CONSENSUS ??????????????R?L?G??R?????P???YQH?KMHKRILGHLSSVYCV?FDR?GRRI

Q4SGZ9_TETNG Q4SGZ9_TETNG FTGSDDCLVKIWGTDDGRLLATLRGHAAEISDMAVSYENTMIAAGSCDKTIRVWCLQTCA Q05BL7_MOUSE Q05BL7_MOUSE FTGSDDCLVKIWATDDGRLLATLRGHAAEISDMAVNYENTMIAAGSCDKMIRVWCLRTCA A7J992_HUMAN A7J992_HUMAN FTGSDDCLVKIWATDDGRLLATLRGHAAEISDMAVNYENTMIAAGSCDKMIRVWCLRTCA PHIP_HUMAN PHIP_HUMAN FTGSDDCLVKIWATDDGRLLATLRGHAAEISDMAVNYENTMIAAGSCDKMIRVWCLRTCA PHIP_MOUSE PHIP_MOUSE FTGSDDCLVKIWATDDGRLLATLRGHAAEISDMAVNYENTMIAAGSCDKMIRVWCLRTCA Q05CQ5_MOUSE Q05CQ5_MOUSE FTGSDDCLVKIWATDDGRLLATLRGHAAEISDMAVNYENTMIAAGSCDKMIRVWCLRTCA BRWD3_HUMAN BRWD3_HUMAN FTGSDDCLVKIWATDDGRLLATLRGHSAEISDMAVNYENTLIAAGSCDKVVRVWCLRTCA BRWD3_MOUSE BRWD3_MOUSE FTGSDDCLVKIWATDDGRLLATLRGHSAEISDMAVNYENTLIAAGSCDKVVRVWCLRTCA Q6NSN0_DANRE Q6NSN0_DANRE ------------------------------------------------------------ Q4S8S0_TETNG Q4S8S0_TETNG FTGSDDCLVKIWATDDGRFLATLRGHSAEICDMAVNYENTLIASASCDKTIRVWC---CG MATCH CONSENSUS FTGSDDCLVKIWATDDGRLLATLRGH?AEISDMAVNYENT?IAAGSCDK??RVWCL?TCA

Q4SGZ9_TETNG Q4SGZ9_TETNG PLAVLEGHAASITSLQFSPLCSGSKRYLSSTGADGTICFWQWDSRTLKFGQRPSKFTERS Q05BL7_MOUSE Q05BL7_MOUSE PLAVLQGHSASITSLQFSPLCSGSKRYLSSTGADGTICFWLWDAGTLKINPRPTKFTERP A7J992_HUMAN A7J992_HUMAN PLAVLQGHSASITSLQFSPLCSGSKRYLSSTGADGTICFWLWDAGTLKINPRPAKFTERP PHIP_HUMAN PHIP_HUMAN PLAVLQGHSASITSLQFSPLCSGSKRYLSSTGADGTICFWLWDAGTLKINPRPAKFTERP PHIP_MOUSE PHIP_MOUSE PLAVLQGHSASITSLQFSPLCSGSKRYLSSTGADGTICFWLWDAGTLKINPRPTKFTERP Q05CQ5_MOUSE Q05CQ5_MOUSE PLAVLQGHSASITSLQFSPLCSGSKRYLSSTGADGTICFWLWDAGTLKINPRPTKFTERP BRWD3_HUMAN BRWD3_HUMAN PVAVLQGHSASITSIQFCPSTKGTNRYLTSTGADGTICFWQWHVKTMKFRDRPVKFTERS BRWD3_MOUSE BRWD3_MOUSE PVAVLQGHSASITSIQFCPSTKGTTRYLTSTGADGTICFWQWHVKTMKFRDRPVKFTERS Q6NSN0_DANRE Q6NSN0_DANRE ------------------------------------------------------------ Q4S8S0_TETNG Q4S8S0_TETNG PVHL-------------------------------SVCCRPTLPPSHPFSDQPVKFVERS MATCH CONSENSUS P?AVL?GH?ASITS?QF?P???G??RYL?STGADGTICFW?W???T?K???RP?KFTER?

Q4SGZ9_TETNG Q4SGZ9_TETNG RPGVQMICSSFSAGGMFLATGSTDHIIRVYYFGSGQPEKISELESHTDKVDSIQFSHCSD Q05BL7_MOUSE Q05BL7_MOUSE RPGVQMICSSFSAGGMFLATGSTDHIIRVYFFGSGQPEKISELEFHTDKVDSIQFSNTSN A7J992_HUMAN A7J992_HUMAN RPGVQMICSSFSAGGMFLATGSTDHIIRVYFFGSGQPEKISELEFHTDKVDSIQFSNTSN PHIP_HUMAN PHIP_HUMAN RPGVQMICSSFSAGGMFLATGSTDHIIRVYFFGSGQPEKISELEFHTDKVDSIQFSNTSN PHIP_MOUSE PHIP_MOUSE RPGVQMICSSFSAGGMFLATGSTDHIIRVYFFGSGQPEKISELEFHTDKVDSIQFSNTSN Q05CQ5_MOUSE Q05CQ5_MOUSE RPGVQMICSSFSAGGMFLATGSTDHIIRVYFFGSGQPEKISELEFHTDKVDSIQFSNTSN BRWD3_HUMAN BRWD3_HUMAN RPGVQISCSSFSSGGMFITTGSTDHVIRIYYLGSEVPEKIAELESHTDKVVAVQFCNNGD BRWD3_MOUSE BRWD3_MOUSE RPGVQISCSSFSSGGMFITTGSTDHVIRIYYLGSEIPEKIAELESHTDKVVAVQFCNNGD Q6NSN0_DANRE Q6NSN0_DANRE ------------------------------------------------------------ Q4S8S0_TETNG Q4S8S0_TETNG RPGVQVSTSSFSSGGMFMATGSTDHMIRVYYLGAETPMKVAEMDAHTDKVVVVQFSNSSD MATCH CONSENSUS RPGVQ??CSSFS?GGMF??TGSTDH?IR?Y??GS??PEKI?ELE?HTDKV???QF?N???

Q4SGZ9_TETNG Q4SGZ9_TETNG --RFVSGSRDGTARIWQLQPQGWRSILLDMQTKLPGKYNPPPLEDKVTKLKVTMVAWDRH Q05BL7_MOUSE Q05BL7_MOUSE --RFVSGSRDGTARIWQFKRREWKSILLDMATRPAGQ-NLQGIEDKITKMKVTMVAWDRH A7J992_HUMAN A7J992_HUMAN --RFVSGSRDGTARIWQFKRREWKSILLDMATRPAGQ-NLQGIEDKITKMKVTMVAWDRH PHIP_HUMAN PHIP_HUMAN --RFVSGSRDGTARIWQFKRREWKSILLDMATRPAGQ-NLQGIEDKITKMKVTMVAWDRH PHIP_MOUSE PHIP_MOUSE --RFVSGSRDGTARIWQFKRREWKSILLDMATRPAGQ-NLQGIEDKITKMKVTMVAWDRH Q05CQ5_MOUSE Q05CQ5_MOUSE --RFVSGSRDGTARIWQFKRREWKSILLDMATRPAGQ-NLQGIEDKITKMKVTMVAWDRH BRWD3_HUMAN BRWD3_HUMAN SLRFVSGSRDGTARIWQYQQQEWKSIVLDMATKMTGN-NLPSGEDKITKLKVTMVAWDRY BRWD3_MOUSE BRWD3_MOUSE SLRFVSGSRDGTARIWQYQQQEWKSIVLDMATKMSGN-NLTSAEDKVTKLKVTMVAWDRY Q6NSN0_DANRE Q6NSN0_DANRE ------------------------------------------------------------ Q4S8S0_TETNG Q4S8S0_TETNG SLRFVSGSRDGTAKIWRYQQQEWKAISLDMAAKLPGN-TVANGDDK-TKLVVTMVAWDRA MATCH CONSENSUS ??RFVSGSRDGTARIWQ????EWKSI?LDMAT???G??N????EDK?TK?KVTMVAWDR?

Q4SGZ9_TETNG Q4SGZ9_TETNG DSTVITAANNLTLKVWNSTTGNLIHVLMGHEDEVFVLESHPFDPRILFSAGHDGNCIVWD Q05BL7_MOUSE Q05BL7_MOUSE DNTVITAVNNMTLKVWNSYTGQLIHVLMGHEDEVFVLEPHPFDPRVLFSAGHDGNVIVWD A7J992_HUMAN A7J992_HUMAN DNTVITAVNNMTLKVWNSYTGQLIHVLMGHEDEVFVLEPHPFDPRVLFSAGHDGNVIVWD PHIP_HUMAN PHIP_HUMAN DNTVITAVNNMTLKVWNSYTGQLIHVLMGHEDEVFVLEPHPFDPRVLFSAGHDGNVIVWD PHIP_MOUSE PHIP_MOUSE DNTVITAVNNMTLKVWNSYTGQLIHVLMGHEDEVFVLEPHPFDPRVLFSAGHDGNVIVWD Q05CQ5_MOUSE Q05CQ5_MOUSE DNTVITAVNNMTLKVWNSYTGQLIHVLMGHEDEVFVLEPHPFDPRVLFSAGHDGNVIVWD BRWD3_HUMAN BRWD3_HUMAN DTTVITAVNNFLLKVWNSITGQLLHTLSGHDDEVFVLEAHPFDQRIILSAGHDGNIFIWD BRWD3_MOUSE BRWD3_MOUSE DTTVITAVNNFLLKVWNSVTGQLLHTLSGHDDEVFVLEAHPFDQRIILSAGHDGNIFIWD Q6NSN0_DANRE Q6NSN0_DANRE ------------------------------------------------------------ Q4S8S0_TETNG Q4S8S0_TETNG DTSVITAVSNYLLKVWSSTTGQLLHVLSGHDDEVFVMEAHPFDSRILLSAGHDGNIYMWD MATCH CONSENSUS D?TVITAVNN??LKVWNS?TGQL?H?L?GH?DEVFVLE?HPFD?R???SAGHDGN???WD

Q4SGZ9_TETNG Q4SGZ9_TETNG LARGVKIRSYFNM-------IEGQGHGALFDCKCSPDGQHFAATDSHGHLLIFGFGSSSK Q05BL7_MOUSE Q05BL7_MOUSE LARGVKVRSYFNM-------IEGQGHGAVFDCKCSPDGQHFACTDSHGHLLIFGFGSSSK A7J992_HUMAN A7J992_HUMAN LARGVKIRSYFNM-------IEGQGHGAVFDCKCSPDGQHFACTDSHGHLLIFGFGSSSK PHIP_HUMAN PHIP_HUMAN LARGVKIRSYFNM-------IEGQGHGAVFDCKCSPDGQHFACTDSHGHLLIFGFGSSSK PHIP_MOUSE PHIP_MOUSE LARGVKVRSYFNM-------IEGQGHGAVFDCKCSPDGQHFACTDSHGHLLIFGFGSSSK Q05CQ5_MOUSE Q05CQ5_MOUSE LARGVKVRSYFNM-------IEGQGHGAVFDCKCSPDGQHFACTDSHGHLLIFGFGSSSK BRWD3_HUMAN BRWD3_HUMAN LDRGTKIRNYFNM-------IEGQGHGAVFDCKFSPDGNHFACTDSHGHLLLFGFGCSKY BRWD3_MOUSE BRWD3_MOUSE LDRGTKIRNYFNM-------IEGQGHGAVFDCKFSPDGNHFACTDSHGHLLLFGFGCSKY Q6NSN0_DANRE Q6NSN0_DANRE ------------------------------------------------------------ Q4S8S0_TETNG Q4S8S0_TETNG LTKGAKIRNFFNMVTQHRGQIEGQGHGAIFDCKFSIDGQHFACTDSHGHLLIFGFGCSKP MATCH CONSENSUS L?RG?K?R?YFNM???????IEGQGHGA?FDCK?SPDG?HFACTDSHGHLL?FGFG?S??

Q4SGZ9_TETNG Q4SGZ9_TETNG YDKIADQMFFHTDYRPLIRDANNYVLDEQTQQAPHLMPPPFLVDVDGNPHPPRYQRLVPG Q05BL7_MOUSE Q05BL7_MOUSE YDKIADQMFFHSDYRPLIRDANNFVLDEQTQQAPHLMPPPFLVDVDGNPHPSRYQRLVPG A7J992_HUMAN A7J992_HUMAN YDKIADQMFFHSDYRPLIRDANNFVLDEQTQQAPHLMPPPFLVDVDGNPHPSRYQRLVPG PHIP_HUMAN PHIP_HUMAN YDKIADQMFFHSDYRPLIRDANNFVLDEQTQQAPHLMPPPFLVDVDGNPHPSRYQRLVPG PHIP_MOUSE PHIP_MOUSE YDKIADQMFFHSDYRPLIRDANNFVLDEQTQQAPHLMPPPFLVDVDGNPHPSRYQRLVPG Q05CQ5_MOUSE Q05CQ5_MOUSE YDKIADQMFFHSDYRPLIRDANNFVLDEQTQQAPHLMPPPFLVDVDGNPHPSRYQRLVPG BRWD3_HUMAN BRWD3_HUMAN YEKIPDQMFFHTDYRPLIRDANNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKFQRLVPG BRWD3_MOUSE BRWD3_MOUSE YEKIPDQMFFHTDYRPLIRDANNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKFQRLVPG Q6NSN0_DANRE Q6NSN0_DANRE ------------------------------------------------------------ Q4S8S0_TETNG Q4S8S0_TETNG FEK----------------------------------------------------RMDAG MATCH CONSENSUS Y?KI?DQMFFH?DYRPLIRDANN?VLDEQTQQAPHLMPPPFLVDVDGNPHP???QRLVPG

Q4SGZ9_TETNG Q4SGZ9_TETNG -REGCRDEQLIPQMGVTSSG----LNQVVSEQAV-DGPSPLDTMIQRLQQEQD-QRLGTG Q05BL7_MOUSE Q05BL7_MOUSE -RENCREEQLIPQMGVTSSG----LNQVLSQQAN-QDISPLDSMIQRLQQEQDLRRSGEA A7J992_HUMAN A7J992_HUMAN -RENCREEQLIPQMGVTSSG----LNQVLSQQAN-QEISPLDSMIQRLQQEQDLRRSGEA PHIP_HUMAN PHIP_HUMAN -RENCREEQLIPQMGVTSSG----LNQVLSQQAN-QEISPLDSMIQRLQQEQDLRRSGEA PHIP_MOUSE PHIP_MOUSE -RENCREEQLIPQMGVTSSG----LNQVLSQQAN-QDISPLDSMIQRLQQEQDLRRSGEA Q05CQ5_MOUSE Q05CQ5_MOUSE -RENCREEQLIPQMGVTSSG----LNQVLSQQAN-QDISPLDSMIQRLQQEQDLRRSGEA BRWD3_HUMAN BRWD3_HUMAN -RENCKDEQLIPQLGYVANGDGEVVEQVIGQQTNDQDESILDGIIRELQREQDLRLINEG BRWD3_MOUSE BRWD3_MOUSE -RENCKDEQLIPQLGYVANGDGEVVEQVIGQQTNDQEESILDGIIRELQREQDLRLINEG Q6NSN0_DANRE Q6NSN0_DANRE -----------P------------------------------------------------ Q4S8S0_TETNG Q4S8S0_TETNG IRGKCNWEILNPHLSFCLLGDGELVEQVLGQQTAENRESLLDNLIRQLQNEQDERHIAAR MATCH * CONSENSUS ?RE?C??EQLIPQ?G????G??????QV??QQ??????S?LD??I??LQ?EQD?R?????

Q4SGZ9_TETNG Q4SGZ9_TETNG DTSGAALANTRAGRGSVGSSP-EVHSPPNVGLRR-SGQIEGVRQMHSNAPRSQMATEGDL Q05BL7_MOUSE Q05BL7_MOUSE GVS----NASRVNRGSVSSTS-EVHSPPNIGLRR-SGQIEGVRQMHSNAPRSEIATERDL A7J992_HUMAN A7J992_HUMAN GIS----NTSRLSRGSISSTS-EVHSPPNVGLRR-SGQIEGVRQMHSNAPRSEIATERDL PHIP_HUMAN PHIP_HUMAN GIS----NTSRLSRGSISSTS-EVHSPPNVGLRR-SGQIEGVRQMHSNAPRSEIATERDL PHIP_MOUSE PHIP_MOUSE GVS----NASRVNRGSVSSTS-EVHSPPNIGLRR-SGQIEGVRQMHSNAPRSEIATERDL Q05CQ5_MOUSE Q05CQ5_MOUSE GVS----NASRVNRGSVSSTS-EVHSPPNIGLRR-SGQIEGVRQMHSNAPRSEIATERDL BRWD3_HUMAN BRWD3_HUMAN DVPHLPVNRAYSVNGALRSPNMDISSSPNIRLRRHSSQIEGVRQMHNNAPRSQMATERDL BRWD3_MOUSE BRWD3_MOUSE DVPHFPINRSYSVNGALSSPNMDIPSSPNIGLRR-SGQIEGVRQMHNNAPRSQMATERDL Q6NSN0_DANRE Q6NSN0_DANRE ---------------------------PNVGLRR-SGQVEGVRQMHNNAPRSQMATERDL Q4S8S0_TETNG Q4S8S0_TETNG QA-----EEAAAAAAEEGEAEVEVVVAPSAAPRR-SGQVDGVWQMQHNTLRSQVATERDL MATCH *. ** *.*::** **: *: **::*** ** CONSENSUS ??????????????G???S??????S?PN?GLRR?SGQIEGVRQMH?NAPRS??ATERDL

Q4SGZ9_TETNG Q4SGZ9_TETNG VAWSRRVLVPELEDASVRRQVNWREAKGEEEINIYQSERRRRTIHSLPKESRVHLTS-EA Q05BL7_MOUSE Q05BL7_MOUSE VAWSRRVVVPELSAGVASRQEEWRTAKGEEEIKSYRSEEKRK-HLTVAKENKILTVS-KN A7J992_HUMAN A7J992_HUMAN VAWSRRVVVPELSAGVASRQEEWRTAKGEEEIKTYRSEEKRK-HLTVPKENKIPTVS-KN PHIP_HUMAN PHIP_HUMAN VAWSRRVVVPELSAGVASRQEEWRTAKGEEEIKTYRSEEKRK-HLTVPKENKIPTVS-KN PHIP_MOUSE PHIP_MOUSE VAWSRRVVVPELSAGVASRQEEWRTAKGEEEIKSYRSEEKRK-HLTVAKENKILTVS-KN Q05CQ5_MOUSE Q05CQ5_MOUSE VAWSRRVVVPELSAGVA-RQEEWRTAKGEEEIKSYRSEEKRK-HLTVAKENKILTVS-KN BRWD3_HUMAN BRWD3_HUMAN MAWSRRVVVNELNNGVSRVQEECRTAKGDIEISLYTVEKKKKPSYTTQRNDYEPSCG-RS BRWD3_MOUSE BRWD3_MOUSE MAWSRRVVVNELNSGVSRVQEECRNAKGDLEVSLYTVEKKKKPSYPIQRNDYQPSCG-RS Q6NSN0_DANRE Q6NSN0_DANRE LAWSRRVVVNEVQAGIFRVMEDCRLAKGEVERSYYIIEKKRK---SVPSTGSQPGDNVRT Q4S8S0_TETNG Q4S8S0_TETNG LAWSRRVMVYEVPHGVYRVSEECRRAKGDLECSFYNAERRKKPVPCTPKNEPLTTRL-RS MATCH :******:* *: . : * ***: * . * *.::: . CONSENSUS ?AWSRRVVV?EL??GV???QEE?R?AKG??E???Y??E?K?K??????????????????

Q4SGZ9_TETNG Q4SGZ9_TETNG LVDE--------GRRSQGNHGYHTRAA--MEETSRQ-------SAEAADDDDSTSEVGEV Q05BL7_MOUSE Q05BL7_MOUSE HAHEHFLDLGDSKKQQANQHNYRTRSA--LEETPR--------PLEELETELVLQMKVKY A7J992_HUMAN A7J992_HUMAN HAHEHFLDLGESKKQQTNQHNYRTRSA--LEETPR--------PSEEIENGSSSSDEGEV PHIP_HUMAN PHIP_HUMAN HAHEHFLDLGESKKQQTNQHNYRTRSA--LEETPR--------PSEEIENGSSSSDEGEV PHIP_MOUSE PHIP_MOUSE HAHEHFLDLGDSKKQQANQHNYRTRSA--LEETPR--------PLEELENGTSSSDEGEV Q05CQ5_MOUSE Q05CQ5_MOUSE HAHEHFLDLGDSKKQQANQHNYRTRSA--LEETPR--------PLEELENGTSSSDEGEV BRWD3_HUMAN BRWD3_HUMAN LR----------RTQRKRQHTYQTRSN--IEHNSQASCQ----NSGVQEDSDSSSEEDET BRWD3_MOUSE BRWD3_MOUSE LR----------RTQRKRQHTYLTRSN--IEHNSQASSQ----TSGVQEDSDSSSEEDET Q6NSN0_DANRE Q6NSN0_DANRE LRRPQ-------RKAQQKRHAYQTRST--RTRRRSGSVQSFSRNEETEVESESEAEQEED Q4S8S0_TETNG Q4S8S0_TETNG LRP---------NKTKRQRHAYQTRSAQVRRRGTRSRNSRNRLNSGSRMDSDSDGEADEQ MATCH .* * **: . : CONSENSUS ???????????????????H?Y?TRS????E?????????????????????S?????E?

Q4SGZ9_TETNG Q4SGZ9_TETNG EIRQINGHSSEEEKEDEEKEPWPDDHSSSSDYSSDYSDWTADAGINLEPPKKSVK--VKK Q05BL7_MOUSE Q05BL7_MOUSE LLSVVGLLRKRSE---------HGT-VMAAPVTTPVIILIGQQMLELTCSHQ------RK A7J992_HUMAN A7J992_HUMAN -VAVSGGTSEEEERA------WHSD-GSSSDYSSDYSDWTADAGINLQPPKKVPKNKTKK PHIP_HUMAN PHIP_HUMAN -VAVSGGTSEEEERA------WHSD-GSSSDYSSDYSDWTADAGINLQPPKKVPKNKTKK PHIP_MOUSE PHIP_MOUSE -LAVSGGTSEEEERA------WHSD-GSSSDYSSDYSDWTADAGINLQPPKKVPKHKTKK Q05CQ5_MOUSE Q05CQ5_MOUSE -LAVSGGTSEEEERA------WHSD-GSSSDYSSDYSDWTADAGINLQPPKKVPKHKTKK BRWD3_HUMAN BRWD3_HUMAN -VGTSDASVEDPVVE------WQSE-SSSSDSSSEYSDWTADAGINLQPPKRQTRQTTRK BRWD3_MOUSE BRWD3_MOUSE -VGTSDASVEDPVVE------WQSE-SSSSDSSSEYSDWIADAGINLQPPKRQTRQATQK Q6NSN0_DANRE Q6NSN0_DANRE QNENSDGTSEGETQ-------WEND-SSSSDSSSEYSDWTADAGINLQPPKRTTRRPARV Q4S8S0_TETNG Q4S8S0_TETNG -VEQSEASSDGEAQ-------WQSE-SSSSDSSSDYSDWTADAGINLQPPKRSSRRPAQP MATCH . . :: :: .: ::* .:: : CONSENSUS ????S????????????????W?????SSSD?SS?YSDWTADAGINLQPPK????????K

Q4SGZ9_TETNG Q4SGZ9_TETNG KNSSSDEGGEKKRDGKKERKKEKADKD------HSIPKKKPKEKSKV------ELQEQGL Q05BL7_MOUSE Q05BL7_MOUSE FLS------------------------------IKPRNQKVVQMKKK------------- A7J992_HUMAN A7J992_HUMAN AESSSDEEEESEKQKQKQIKKEKKKVNEEKDGPISPKKKKPKERKQK-RLAVGELTENGL PHIP_HUMAN PHIP_HUMAN AESSSDEEEESEKQKQKQIKKEKKKVNEEKDGPISPKKKKPKERKQK-RLAVGELTENGL PHIP_MOUSE PHIP_MOUSE PESSSDEEEESENQKQKHIKKERKKANEEKDGPTSPKKKKPKERKQK-RLAVGELTENGL Q05CQ5_MOUSE Q05CQ5_MOUSE PESSSDEEEESENQKQKHIKKERKKANEEKDGPTSPKKKKPKEKKKK------------- BRWD3_HUMAN BRWD3_HUMAN ICSSSDEENLKS---------------------LEERQKKPKQTRKK---KGGLVSIAGE BRWD3_MOUSE BRWD3_MOUSE IYSSSEDENLK----------------------LEDRQKKPKQTKKK---KGGLVSMAGE Q6NSN0_DANRE Q6NSN0_DANRE AVSSSSEDEEGTGQGEGEAAQTTK---------QAEKKKKPKQRSVP----AGEL----- Q4S8S0_TETNG Q4S8S0_TETNG QGYSSSEEEEGDNKTKEAKK-------------NEEKKKKSKETKQRPTSSLGEL----- MATCH ::* : CONSENSUS ??SSS?E???????????????????????????????KKPK??????????????????

Q4SGZ9_TETNG Q4SGZ9_TETNG TLEEWLPSAWITDTVPRRSPYIPQMGDEVRTFF--FTVVVSLMAEHAFVCTKTRLSVLFF Q05BL7_MOUSE Q05BL7_MOUSE -----------------------------------------------------------N A7J992_HUMAN A7J992_HUMAN TLEEWLPSTWITDTIPRRCPFVPQMGDEVYYFRQGHEAYVEMARKNKIYSINPKKQPWHK PHIP_HUMAN PHIP_HUMAN TLEEWLPSTWITDTIPRRCPFVPQMGDEVYYFRQGHEAYVEMARKNKIYSINPKKQPWHK PHIP_MOUSE PHIP_MOUSE TLEEWLPSAWITDTLPRRCPFVPQMGDEVYYFRQGHEAYVEMARKNKIYSINPKKQPWHK Q05CQ5_MOUSE Q05CQ5_MOUSE ------------------------------------------------------------ BRWD3_HUMAN BRWD3_HUMAN PNEEWFAPQWILDTIPRRSPFVPQMGDELIYFRQGHEAYVRAVRKSKIYSVNLQKQPWNK BRWD3_MOUSE BRWD3_MOUSE PNEEWLAPQWILDTIPRRSPFVPQMGDELIYFRQGHEAYVRAVRKSKIYSVNLQKQPWNK Q6NSN0_DANRE Q6NSN0_DANRE --EEWLPPSWIMETIPRRSPFVPQMGDELIYFRQGHQAYVRAVSRAKAYSINPQKQPWNR Q4S8S0_TETNG Q4S8S0_TETNG NPEEWLPPSWIMETVPRCSPFVPQMGDELIYFKQGHQAYARAVRRAKAYSINPQKQPWNR MATCH CONSENSUS ??EEW????WI??T?PR??P??PQMGDE???F????????????????????????????

Q4SGZ9_TETNG Q4SGZ9_TETNG CGTQEQELMKIVGIKYEVGLPTLCCLKLAFLDPDTGKLTGGSFSMKYHDMPDVIDFLVLR Q05BL7_MOUSE Q05BL7_MOUSE LKTRSKNILK-------------------------------------------------- A7J992_HUMAN A7J992_HUMAN MELREQELMKIVGIKYEVGLPTLCCLKLAFLDPDTGKLTGGSFTMKYHDMPDVIDFLVLR PHIP_HUMAN PHIP_HUMAN MELREQELMKIVGIKYEVGLPTLCCLKLAFLDPDTGKLTGGSFTMKYHDMPDVIDFLVLR PHIP_MOUSE PHIP_MOUSE MELREQELMKIVGIKYEVGLPTLCCLKLAFLDPDTGKLTGGSFTMKYHDMPDVIDFLVLR Q05CQ5_MOUSE Q05CQ5_MOUSE ------------------------------------------------------------ BRWD3_HUMAN BRWD3_HUMAN MDLREQEFVKIVGIKYEVGPPTLCCLKLAFLDPISGKMTGESFSIKYHDMPDVIDFLVLH BRWD3_MOUSE BRWD3_MOUSE MDLREQEFVKIVGIKYEIGPPTLCCLKLAFLDPISGKMTGESFSIKYHDMPDVIDFLVLH Q6NSN0_DANRE Q6NSN0_DANRE LNLRDQESVKVVGIKYEVGPPTLCCLKLAILDLTSGKMTNESFSLKYHDMPDVIDFLVLQ Q4S8S0_TETNG Q4S8S0_TETNG LNLRDQESVKVVGIKYEVGPPTLCCLKLAFLDPVSGKMTNESFSLKYHDMPDVIDFLVLQ MATCH CONSENSUS ???R?QE??K?VGIKYE?G?PTLCCLKLA?LD???GK?T??SF??KYHDMPDVIDFLVL?

Q4SGZ9_TETNG Q4SGZ9_TETNG QQFDNARRRQWSIGDRFRSVIDDAWWFGTIESQEPYQPQYPDSLFLCYNVCWDNGDTEKM Q05BL7_MOUSE Q05BL7_MOUSE ------------------------------------------------------------ A7J992_HUMAN A7J992_HUMAN QQFDDAKYRRWNIGDRFRSVIDDAWWFGTIESQEPLQLEYPDSLFQCYNVCWDNGDTEKM PHIP_HUMAN PHIP_HUMAN QQFDDAKYRRWNIGDRFRSVIDDAWWFGTIESQEPLQLEYPDSLFQCYNVCWDNGDTEKM PHIP_MOUSE PHIP_MOUSE QQFDDAKYRPWNIGDRFRSVIDDAWWFGTIESQEPLQPEYPDSLFQCYNVCWDNGDTEKM Q05CQ5_MOUSE Q05CQ5_MOUSE ------------------------------------------------------------ BRWD3_HUMAN BRWD3_HUMAN QFYNEAKERNWQIGDRFRSIIDDAWWFGTVESQQPFQPEYPDSSFQCYSVHWDNNEREKM BRWD3_MOUSE BRWD3_MOUSE QFYNEAKERNWQIGDRFRSIIDDAWWFGTVESQQPFQPEYPDSSFQCYSVHWDNNEREKM Q6NSN0_DANRE Q6NSN0_DANRE QFYNEAKERNWQPGQRFRSIIDDAWWFGSLECQEPFESEYPDSLFQCYIVRWDNGEREKM Q4S8S0_TETNG Q4S8S0_TETNG QFYNEAKEHNWQPGMRFRSIIDDAWWFGLVEDQEPLQPEYPDSLFQCFAVKWDNGECEKM MATCH CONSENSUS Q????A????W??G?RFRS?IDDAWWFG??E?Q?P????YPDS?F?C??V?WDN???EKM

Q4SGZ9_TETNG Q4SGZ9_TETNG SPWDMEPVPDDATFPDELGTSVPLTEDEQKELLYVPLEGEWGCQSRAEECERIIKAIDQL Q05BL7_MOUSE Q05BL7_MOUSE ------------------------------------------------------------ A7J992_HUMAN A7J992_HUMAN SPWDMELIPNNAVFPEELGTSVPLTDGECRSLIYKPLDGEWGTNPRDEECERIVAGINQL PHIP_HUMAN PHIP_HUMAN SPWDMELIPNNAVFPEELGTSVPLTDGECRSLIYKPLDGEWGTNPRDEECERIVAGINQL PHIP_MOUSE PHIP_MOUSE SPWDMELIPNNAVFPEELGTSVPLTDVECRSLIYKPLDGEWGANPRDEECERIVGGINQL Q05CQ5_MOUSE Q05CQ5_MOUSE ------------------------------------------------------------ BRWD3_HUMAN BRWD3_HUMAN SPWDMEPIPEGTAFPDEVGAGVPVSQEELTALLYKPQEGEWGAHSRDEECERVIQGINHL BRWD3_MOUSE BRWD3_MOUSE SPWDMEPIPDGTAFPDEVGAGIPVSQEELTALLYKPQEGEWGAHSRDEECERVIQGINNL Q6NSN0_DANRE Q6NSN0_DANRE SPWDIEPIPEEAPLPEEDGDSVPVTEDELQALLYSPQEGEWGLHTRDEECERVITAIDQL Q4S8S0_TETNG Q4S8S0_TETNG SPWDMEPIPEEAALPEQVGDGVEVAEEEMKALLYRPQEGEWGAHTRDEECERVICGIEQL MATCH CONSENSUS SPWD?E??P?????P???G????????E???L?Y?P??GEWG???R?EECER????I??L

Q4SGZ9_TETNG Q4SGZ9_TETNG CTLDVAAPFAFPVDLQAYPTYCTVVAYVTDLSTIRQRLVNRFYRRLSSLMWEVRYIEHNT Q05BL7_MOUSE Q05BL7_MOUSE ------------------------------------------------------------ A7J992_HUMAN A7J992_HUMAN MTLDIASAFVAPVDLQAYPMYCTVVAYPTDLSTIKQRLENRFYRRVSSLMWEVRYIEHNT PHIP_HUMAN PHIP_HUMAN MTLDIASAFVAPVDLQAYPMYCTVVAYPTDLSTIKQRLENRFYRRVSSLMWEVRYIEHNT PHIP_MOUSE PHIP_MOUSE MTLDIASAFVAPVDLQAYPMYCTVVAYPTDLSTIKQRLENRFYRRFSSLMWEVRYIEHNT Q05CQ5_MOUSE Q05CQ5_MOUSE ------------------------------------------------------------ BRWD3_HUMAN BRWD3_HUMAN LSLDFASPFAVPVDLSAYPLYCTVVAYPTDLNTIRRRLENRFYRRISALMWEVRYIEHNA BRWD3_MOUSE BRWD3_MOUSE LSLDFASPFAVPVDLSAYPLYCTVVAYPTDLNTIKQRLENRFYRRISALMWEVRYIEHNA Q6NSN0_DANRE Q6NSN0_DANRE LTLDVAKAFSNPVNLREYPLYCTVVAYLTDLSTIRTRLVHRFYRRISALMWEVRYIEHNA Q4S8S0_TETNG Q4S8S0_TETNG FTLEVAKAFASPVNLQDYPLYCAVVAYPTDLSTIRKRLENRFYRRISALMWEVRYIEHNA MATCH CONSENSUS ??L??A??F??PV?L??YP?YC?VVAY?TDL?TI??RL??RFYRR?S?LMWEVRYIEHN?

Q4SGZ9_TETNG Q4SGZ9_TETNG QTFNEPRSFIVTTAKFVSDLMLQFIKDQSLTDLMPLYKTMKKATFSDSEDEEEADDDEDE Q05BL7_MOUSE Q05BL7_MOUSE ------------------------------------------------------------ A7J992_HUMAN A7J992_HUMAN RTFNEPGSPIVKSAKFVTDLLLHFIKDQTCYNIIPLYNSMKKKVLSDSEDEE-------K PHIP_HUMAN PHIP_HUMAN RTFNEPGSPIVKSAKFVTDLLLHFIKDQTCYNIIPLYNSMKKKVLSDSEDEE-------K PHIP_MOUSE PHIP_MOUSE RTFNEPGSPIVKSAKFVTDLLLHFIKDQTCYNIIPLYNSMKKKVLSDSEEEE-------K Q05CQ5_MOUSE Q05CQ5_MOUSE ------------------------------------------------------------ BRWD3_HUMAN BRWD3_HUMAN RTFNEPDSPIVKAAKIVTDVLLRFIGDQSCTDILDTYNKIKAEERNSTDAEEDT-EIVDL BRWD3_MOUSE BRWD3_MOUSE RTFNEPDSPIVKAAKIVTDVLLRFIGDQSCSDILDTYNKIKAEDPDSSDLEEDS-EMVDL Q6NSN0_DANRE Q6NSN0_DANRE RTFNEPQSPIVTAAKTVSDVLLRFIRDQNCTDILDLYNKMKSEFSSEEDEEE----TVDV Q4S8S0_TETNG Q4S8S0_TETNG RTFNEPQSPIVATAKVVTDVLLRYIGDQSCTDILDLYHKLKADISSGEEAKV---SVSLL MATCH CONSENSUS ?TFNEP?S?IV??AK?V?D??L??I?DQ????????Y???K???????????????????

Q4SGZ9_TETNG Q4SGZ9_TETNG DSNTPGTSTRNHRNPQPMQRRLRTRPHSYNPQAWRGRCKELLDLIFQCEDSEPFREPVDL Q05BL7_MOUSE Q05BL7_MOUSE ---------------RKEKKQMKKK----------------------------------- A7J992_HUMAN A7J992_HUMAN DADVPGTSTR-KRKDHQPRRRLRNRAQSYDIQAWKKQCEELLNLIFQCEDSEPFRQPVDL PHIP_HUMAN PHIP_HUMAN DADVPGTSTR-KRKDHQPRRRLRNRAQSYDIQAWKKQCEELLNLIFQCEDSEPFRQPVDL PHIP_MOUSE PHIP_MOUSE DADVPGTSTR-KRKDHQPRRRLRNRAQSYDIQAWKKQCQELLNLIFQCEDSEPFRQPVDL Q05CQ5_MOUSE Q05CQ5_MOUSE ------------------------------------------------------------ BRWD3_HUMAN BRWD3_HUMAN DSDGPGTSSG-----RRVKCRGRRQSLKCNPDAWKKQCKELLSLIYEREDSEPFRQPADL BRWD3_MOUSE BRWD3_MOUSE DSDGPGTSSG-----RRAKCRGRRQSLKCNPDAWKKQCEELLSLIYEREDSEPFRQPADP Q6NSN0_DANRE Q6NSN0_DANRE DSDTPGTSTG----QRRSNSTPQKRGVVLDINAWHKQCKDLVRRMIVSSDSEPFRQPVDL Q4S8S0_TETNG Q4S8S0_TETNG PPASAYLFSNVPKNTHLSNQNSNKRGAALEVKAWRGRCRELLRRMVASPDSQPFRQPVDL MATCH CONSENSUS ????????????????????????????????AW???C??L????????DS?PFR?P?D?

Q4SGZ9_TETNG Q4SGZ9_TETNG QEYP-------------------------DYLEIVESPMDFGTVLSTLTEGKYQSPIELC Q05BL7_MOUSE Q05BL7_MOUSE ------------------------------------------------------------ A7J992_HUMAN A7J992_HUMAN LEYP-------------------------DYRDIIDTPMDFATVRETLEAGNYESPMELC PHIP_HUMAN PHIP_HUMAN LEYP-------------------------DYRDIIDTPMDFATVRETLEAGNYESPMELC PHIP_MOUSE PHIP_MOUSE LEYP-------------------------DYRDIIDTPMDFATVRETLEAGNYESPMELC Q05CQ5_MOUSE Q05CQ5_MOUSE ------------------------------------------------------------ BRWD3_HUMAN BRWD3_HUMAN LSYPGHQEQEGESSESVVPERQQDSSLSEDYQDVIDTPVDFSTVKETLEAGNYGSPLEFY BRWD3_MOUSE BRWD3_MOUSE QSYPVQQQQEGESSQSVPPDR-QDPSLSEDYQDGIDTPMDFSTVKETLESGNYDSPLEFY Q6NSN0_DANRE Q6NSN0_DANRE FTYP-------------------------DYRDIIDTPMDLGTVSETLTGGNYENPIEFA Q4S8S0_TETNG Q4S8S0_TETNG FEYP-------------------------DYRDIIDTPMDLGTVSETLYEGNYENPMEFA MATCH CONSENSUS ??YP?????????????????????????DY??????P?D??TV??TL??G?Y??P?E??

Q4SGZ9_TETNG Q4SGZ9_TETNG KDVRLIFSNSKAYTPSKKSRIYSMSLRLSALFEEHVGPILADYRAIHGLTGKLSRQSTDR Q05BL7_MOUSE Q05BL7_MOUSE -------------------------------MDQH------------------------- A7J992_HUMAN A7J992_HUMAN KDVRLIFSNSKAYTPSKRSRIYSMSLRLSAFFEEHISSVLSDYKSALRF----------- PHIP_HUMAN PHIP_HUMAN KDVRLIFSNSKAYTPSKRSRIYSMSLRLSAFFEEHISSVLSDYKSALRF----------- PHIP_MOUSE PHIP_MOUSE KDVRLIFSNFKAYTPSKRSRIYSMSLRLSAFFEEHISSVLSDYKSALRF----------- Q05CQ5_MOUSE Q05CQ5_MOUSE ------------------------------------------------------------ BRWD3_HUMAN BRWD3_HUMAN KDVRQIFNNSKAYTSNKKSRIYSMMLRLSALFESHIKNIISEYKSAIQS----------- BRWD3_MOUSE BRWD3_MOUSE KDVRQIFSNSKAYTSNKKSRIYSMTLRLSALFENHIKNIISDYKSAIQS----------- Q6NSN0_DANRE Q6NSN0_DANRE KDVRLIFSNSKAYTPNKKSRIYSMTLSLSAFFENQIIPIISDYKSAVQN----------- Q4S8S0_TETNG Q4S8S0_TETNG KDIRLIFSNSKAYTPNKKSQIYAMTLSLSAFFEKSIISIISDYKSAIQN----------- MATCH CONSENSUS KD?R?IF?N?KAYT??K?S?IY?M?L?LSA?FE?????????Y?????????????????

Q4SGZ9_TETNG Q4SGZ9_TETNG QTRHTTDRQTRHAMKRRRRRSESPASSTASSPERKRRMSSRVLTKKESSPAPSRPPSLRQ Q05BL7_MOUSE Q05BL7_MOUSE ---HQRKK----------------------SPKKKK------------------------ A7J992_HUMAN A7J992_HUMAN ---HKRNTIT--KRRKKRNRSSSVSSSAASSPERKKRILKPQLKSESSTSAFSTPTR--- PHIP_HUMAN PHIP_HUMAN ---HKRNTIT--KRRKKRNRSSSVSSSAASSPERKKRILKPQLKSESSTSAFSTPTR--- PHIP_MOUSE PHIP_MOUSE ---HKRNTIS--KKRKKRNRSSSLSSSAASSPERKKRILKPQLKSEVSTSPFSIPTR--- Q05CQ5_MOUSE Q05CQ5_MOUSE ------------------------------------------------------------ BRWD3_HUMAN BRWD3_HUMAN ---QKRRRPR--YRKRLRSSSSSLSSSGAPSPKGKQKQMKLQPKNDQNTSVSHARTSSPF BRWD3_MOUSE BRWD3_MOUSE ---QKRRRPR--YRKRLRSSSSSLSSSRAPSPKGKQKQMKLQPKNDQNTSVAYARTSSPF Q6NSN0_DANRE Q6NSN0_DANRE ---QRRSQQRLMCSKRLQSSSPN-------SPKGKQKSGKKTLQMSAK-----ARTR--- Q4S8S0_TETNG Q4S8S0_TETNG ---ERRTRQRLSYRDRLQNGGSSPPVSPSPSSEKQQR----------------------- MATCH CONSENSUS ?????R????????????????????????SP??K?????????????????????????

Q4SGZ9_TETNG Q4SGZ9_TETNG SIPTKQAPQLVNGKAEALAGGRTRSAARNSTHTPPVASSTQSATSNTQTTAGSATFACRF Q05BL7_MOUSE Q05BL7_MOUSE ------------------------------------------------------------ A7J992_HUMAN A7J992_HUMAN SIPPRHNAAQINGKTESSSVVRTRSNRVVVDPVVTEQPSTSSAAKTFITKANASAIPGKT PHIP_HUMAN PHIP_HUMAN SIPPRHNAAQINGKTESSSVVRTRSNRVVVDPVVTEQPSTSSAAKTFITKANASAIPGKT PHIP_MOUSE PHIP_MOUSE SVLPRHNAAQMNGKPESSSVVRTRSNRVAVDPVVTEQPSTSSATKAFVSKTNTSAMPGKA Q05CQ5_MOUSE Q05CQ5_MOUSE ------------------------------------------------------------ BRWD3_HUMAN BRWD3_HUMAN SSPVSDAAEGLSLYLLDDEPDGPFSSSSFGGYSRSGNSHDPGKAKSFRNRV--LPVKQDH BRWD3_MOUSE BRWD3_MOUSE SSPVSDAAEGVSLYLLDDEGDGPFSPSSFSGYSRSGNSHDPGKAKSFRNRV--LPAKQDH Q6NSN0_DANRE Q6NSN0_DANRE KSSQDSNVAQVD---EDSQPSSSSSSSSSSSSSSSFSSEQAGANRVTRSQVTSSKSSGVF Q4S8S0_TETNG Q4S8S0_TETNG ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

Q4SGZ9_TETNG Q4SGZ9_TETNG MFTATLRVNKRIIVTFHFCSESTRLLRGHSSNSTPPAAEKVTP-SPTMETNSGGSTRRKL Q05BL7_MOUSE Q05BL7_MOUSE ------------------------------------------------------------ A7J992_HUMAN A7J992_HUMAN ILENSVKHSKALNTLSS--PGQSSFSHGTRNNSAKENMEKEKPVKRKMKSSVLPKASTLS PHIP_HUMAN PHIP_HUMAN ILENSVKHSKALNTLSS--PGQSSFSHGTRNNSAKENMEKEKPVKRKMKSSVLPKASTLS PHIP_MOUSE PHIP_MOUSE MLENSVRHSKALSTLSS--PDPLTFSHATKNNSAKENMEKEKPVKRKMKSSVFSKASPLP Q05CQ5_MOUSE Q05CQ5_MOUSE ------------------------------------------------------------ BRWD3_HUMAN BRWD3_HUMAN SLDGPLTNGDGREPRTGIKRKLLSASEEDENMGGEDKEKKETKEKSHLSTSESGELGSSL BRWD3_MOUSE BRWD3_MOUSE SLDGPLTNVDGREPRTGAKRKLLSASEEDESMGGEEKEMKETKEQVHLSSSESGELGSSL Q6NSN0_DANRE Q6NSN0_DANRE LPNGGRSSRRRRAVLTE---------------------EGEVSECESTSSSSSSTSASSS Q4S8S0_TETNG Q4S8S0_TETNG ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

Q4SGZ9_TETNG Q4SGZ9_TETNG KPPVRHSPGS-PDSPSSHNTVHLNGHSSH-VTLGEGKKGRKSRVDAPASPPEATTPGSPS Q05BL7_MOUSE Q05BL7_MOUSE ------------------------------------------------------------ A7J992_HUMAN A7J992_HUMAN KSSAVIEQGDCKNNALVPGTIQVNGHGGQPSKLVKRGPGRKPKVEVNTNS-----GEIIH PHIP_HUMAN PHIP_HUMAN KSSAVIEQGDCKNNALVPGTIQVNGHGGQPSKLVKRGPGRKPKVEVNTNS-----GEIIH PHIP_MOUSE PHIP_MOUSE KSAAVIEQGECKNNVLIPGTIQVNGHGGQPSKLVKRGPGRKPKVEVNTSS-----GEVTH Q05CQ5_MOUSE Q05CQ5_MOUSE ------------------------------------------------------------ BRWD3_HUMAN BRWD3_HUMAN SSESTCGSDSDSESTSRTDQDYVDGDHDY-SKFIQTRPKRKLRKQHGNGK-----RNWKT BRWD3_MOUSE BRWD3_MOUSE SSESTSGSDSDSESTSRTDQDYVDGDHDY-SKFIQTRPKRKLRKQHTNGK-----RNWKT Q6NSN0_DANRE Q6NSN0_DANRE SSATSSSSSESDDSSAEVSGFADGGDHDYSKAPQHKQKGKAPAPPPPSPPPPPPAPTIDN Q4S8S0_TETNG Q4S8S0_TETNG ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

Q4SGZ9_TETNG Q4SGZ9_TETNG RPRGRPPGKKRGRKSKQEMEELRGSSIPDDDLDQSTGDECGPSSAQETAVMSDSGVASPP Q05BL7_MOUSE Q05BL7_MOUSE ------------------------------------------------------------ A7J992_HUMAN A7J992_HUMAN KKRGRKPKKLQYAKP-EDLEQNNVHPIRDEVLPSSTCNFLSETNNVKEDLLQKKN----- PHIP_HUMAN PHIP_HUMAN KKRGRKPKKLQYAKP-EDLEQNNVHPIRDEVLPSSTCNFLSETNNVKEDLLQKKN----- PHIP_MOUSE PHIP_MOUSE KKRGRKPKNLQCAKQ-ENSEQNNMHPIRADVLPSSTCNFLSETNAVKEDLLQKKS----- Q05CQ5_MOUSE Q05CQ5_MOUSE ------------------------------------------------------------ BRWD3_HUMAN BRWD3_HUMAN RGTGGRGRWGRWGRW-SRGGRGRGGRGRG-----------SRGRGGGGTRGRGRG----- BRWD3_MOUSE BRWD3_MOUSE RGTGGRGRWGRWGRW-SRGGRGRGGRGRG-----------GRGRGGGGGRGRGRG----- Q6NSN0_DANRE Q6NSN0_DANRE PKRKRKGEEEQSAEP-EKRPRRTSSR--------------EEEEEEEEEEVDDEP----- Q4S8S0_TETNG Q4S8S0_TETNG ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

Q4SGZ9_TETNG Q4SGZ9_TETNG RRRGRPRTTRTDEAAPPAESPEPSPLRRSSRRTNEEVTPPPQLTQSKSSRKESPKEDAGD Q05BL7_MOUSE Q05BL7_MOUSE ------------------------------------------------------------ A7J992_HUMAN A7J992_HUMAN -RGGRKPKRKMKTQKLDADLLVPASVKVLRRSNRKKIDDPIDEEEEFEELKGSE------ PHIP_HUMAN PHIP_HUMAN -RGGRKPKRKMKTQKLDADLLVPASVKVLRRSNRKKIDDPIDEEEEFEELKGSE------ PHIP_MOUSE PHIP_MOUSE -RGGRKPKRKMKTHNLDSELIVPTNVKVLRRSNRKKTDDPIDEEEEFEELKGSE------ Q05CQ5_MOUSE Q05CQ5_MOUSE ------------------------------------------------------------ BRWD3_HUMAN BRWD3_HUMAN -RGGRGASRGAT------------------RAKRARIADD-EFDTMFSGRFSRL------ BRWD3_MOUSE BRWD3_MOUSE -RGGRGASRGSS------------------RAKRARVADD-EFDTMFSGRFSRL------ Q6NSN0_DANRE Q6NSN0_DANRE -EEEEEPDEEEEPEEEEEESDDENVISPSKRS---------------NQRTPKS------ Q4S8S0_TETNG Q4S8S0_TETNG -SRGRGC----------------------------------------------------- MATCH CONSENSUS ????????????????????????????????????????????????????????????

Q4SGZ9_TETNG Q4SGZ9_TETNG AAGGSMRTRNQGRRSAWYMEEDSEEEQRQLLFEDSSITFGTSSKGRVRKLTEKAK-ANLI Q05BL7_MOUSE Q05BL7_MOUSE ------------------------------------------------------------ A7J992_HUMAN A7J992_HUMAN ---PHMRTRNQGRRTAFYNEDDSEEEQRQLLFEDTSLTFGTSSRGRVRKLTEKAK-ANLI PHIP_HUMAN PHIP_HUMAN ---PHMRTRNQGRRTAFYNEDDSEEEQRQLLFEDTSLTFGTSSRGRVRKLTEKAK-ANLI PHIP_MOUSE PHIP_MOUSE ---PHMRTRNQGRRTAFYNEDDSEEEQRQLLFEDTSLTFGTSSRGRVRKLTEKAK-ANLI Q05CQ5_MOUSE Q05CQ5_MOUSE ------------------------------------------------------------ BRWD3_HUMAN BRWD3_HUMAN ---PRIKTRNQGRRTVLYNDDSDNDN---FVSTEDPLNLGTSRSGRVRKMTEKARVSHLM BRWD3_MOUSE BRWD3_MOUSE ---PRIKTRNQGRRTVLYNDDSDNDN---FVSTEDPLNLGTSRSGRVRKMTEKARVSHLM Q6NSN0_DANRE Q6NSN0_DANRE ---GRVNTRNQGRRTVLYNDDSEEEG-----PTSDPLNLGMSRSGRVRRMTERARVSHLM Q4S8S0_TETNG Q4S8S0_TETNG ---PTVLSK--------FRDEQ-------------------------------------- MATCH CONSENSUS ????????????????????????????????????????????????????????????

Q4SGZ9_TETNG Q4SGZ9_TETNG GW-- Q05BL7_MOUSE Q05BL7_MOUSE ---- A7J992_HUMAN A7J992_HUMAN GW-- PHIP_HUMAN PHIP_HUMAN GW-- PHIP_MOUSE PHIP_MOUSE GW-- Q05CQ5_MOUSE Q05CQ5_MOUSE ---- BRWD3_HUMAN BRWD3_HUMAN GWNY BRWD3_MOUSE BRWD3_MOUSE GWNY Q6NSN0_DANRE Q6NSN0_DANRE GWTH Q4S8S0_TETNG Q4S8S0_TETNG ---- MATCH CONSENSUS ????


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