Alignment of the gene Family HOG000008235 of HOGENOM

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Threshold: 50% 80% 100%
Size: Bigger Smaller Normal
Isoforms are ON
AILMEGL194998_1_PE1 NOISO ------------------------------------------------------------ ANOCA81_2_PE4 NOISO ------------------------------------------------------------ BOVINX_88_PE9 NOISO ------------------------------------------------------MDPLSV CALJAX_9_PE1 ENSCJAG00000000928 -------------------------------------------------------DPLSG CALJAX_9_PE2 ISOFORMIN ------------------------------------------------------------ CANFAX_7_PE3 NOISO -----------------------------------------------------------M CAVPO126_2_PE3 NOISO -----------------------------------------------------------V CHICK1_PE2106 NOISO ------------------------------------------------------------ DANRE11_47_PE9 NOISO ------------------------------------------------------------ DANRE6_32_PE4 NOISO ------------------------------------------------------------ ECHTEGS_4788_PE1 NOISO ------------------------------------------------------------ FELCAGS_2696_PE1 NOISO ------------------------------------------------------------ FUGRU13_1_PE137 ISOFORMIN -----------SGGLDPRCREDEAWKLVDVYLSGGAPWGF------TLRGGLEHREPLLI FUGRU13_1_PE138 ISOFORMIN -----------SGGLDPRCREDEAWKLVDVYLSGGAPWG------FTLRGGLEHREPLLI FUGRU13_1_PE139 ENSTRUG00000012349 -------------------------------MEAGGCISFRRGAMGVYTQGLEHREPLLI FUGRU13_1_PE140 ISOFORMIN ------------------------------------------------------------ FUGRU57_1_PE17 NOISO -CHGLRGSQRPPESSSREEKVVEDEELVEVLLQGKAPWGF------TLRGGAEHREPLII GASACGROUPI_29_PE25 NOISO ------------RGSEQKSRKAEEGEVVQMLLRGNAPWGF------TLRGGTEHRGPLVT GASACGROUPVIII_19_PE38 NOISO EADGLWTVTQKAGDLEQRSRDGESWKLVDVCLSGGAPWGF------TLRGGLEHREPLLI GORGOX_11_PE1 NOISO -MEGAEPRARPERLAEAETRAADGGRLVEVQLSGGAPWGF------TLKGGREHGEPLVI HORSEX_7_PE4 ISOFORMIN ------------------------------------------------------------ HORSEX_7_PE5 ENSECAG00000012150 ------------------------------------------------------------ HSX_PE143 ENSG00000146950 -MEGAEPRARPERLAEAETRAADGGRLVEVQLSGGAPWGF------TLKGGREHGEPLVI LOXAF94_6_PE2 NOISO -----------------------------------------------------------M MACEUGS_5635_PE1 NOISO ------------------------------------------------------------ MACMUX_8_PE9 ENSMMUG00000006193 -------------------------------------------------------DPLSG MICMUGS_799_PE3 NOISO ------------------------------------------------------------ MONDO7_34_PE7 ENSMODG00000017449 ------------------------------------------------------------ MONDO7_34_PE8 ISOFORMIN ------------------------------------------------------------ MOUSEX_PE1950 ISOFORMIN -MEGAEPRARPERLAEAEAPATDGVRLVEVQLSGGAPWGF------TLKGGREHGEPLVI MOUSEX_PE1951 ENSMUSG00000045180 -MEGAEPRARPERLAEAEAPATDGVRLVEVQLSGGAPWGF------TLKGGREHGEPLVI MYOLUGS_3236_PE1 NOISO -MEGAESHAWPEPWAC----TAEGGR-PKLQLNDG-ASAL------TLKAARQHGPPRVI ORNANULTRA462_6_PE4 ENSOANG00000009689 ------------------------------------------------------------ ORNANULTRA462_6_PE5 ISOFORMIN ------------------------------------------------------------ ORYLA2_17_PE12 NOISO ---------------------ASAGRMKWVLLQGRAPWGF------TLRGGTEHREPLII ORYLA4_32_PE17 NOISO -KQSITPRDRPLSLRNQRSREAEGWKLVNVCLLGGAPWGF------TLRGGLEHQEPLVI OTOGAGS_2886_PE1 NOISO ------------------------------------------------------------ PANTRX_11_PE1 NOISO ------------------------------------------------------------ PIGX_6_PE3 NOISO ------------------------------------------------------------ POEGU1_20_PE6 NOISO ------------------------------------------------------------ PONPYX_10_PE2 NOISO -MEGAEPRARPERLAEAETRAADGGRLVEVQLTGGAPWGF------TLKGGREHGEPLVI PTEVAGS_2083_PE1 NOISO ------------------------------------------------------------ RATX_PE414 ENSRNOG00000024322 -MEGAEPRARPERLAEAEARATDGVRLVEVQLSGGAPWGF------TLKGGREHGEPLVI RATX_PE415 ISOFORMIN ------------------------------------------------------------ SPETRGS_3166_PE1 NOISO ------------------------------------------------------------ TARSYGS_4663_PE1 NOISO ------------------------------------------------------------ TETNG3_PE72 ENSTNIG00000017158 ---ADRAKWWRELEPSGSSSAPQQEELVEVLLRGTAPWGF------TLRGGAEHREPLVI TETNG3_PE73 ISOFORMIN --------------------------MVEVLLRGTAPWGF------TLRGGAEHREPLVI TURTRGS_550_PE3 NOISO -MEGAEPRVRPERLAEAEARAADGGRLVEVQLSGGAPWGF------TLKGGREHGEPLVI MATCH CONSENSUS ????????????????????????????????????????????????????????????

AILMEGL194998_1_PE1 NOISO -QIEEGSKAAAVDKLLAGDEIVGINDIGLSGFRQEAICLVKGSHKTLKLVVK--RKNEVS ANOCA81_2_PE4 NOISO ------------------------------------------------------------ BOVINX_88_PE9 NOISO LQVEEGSKAAAVDKLLAGDEIVGINDVGLSGFRQEAICLVKGSHKTLKLVVKSPRRNELN CALJAX_9_PE1 ENSCJAG00000000928 NKIEEGSKAAAVDKLLAGDEIVSINDIDLSGFRQEAICLVKGSHKTLKLVVK--RRSELG CALJAX_9_PE2 ISOFORMIN -QIEEGSKAAAVDKLLAGDEIVSINDIDLSGFRQEAICLVKGSHKTLKLVVK--RRSELG CANFAX_7_PE3 NOISO LQIEEGSKAAAVDKLLAGDEIVGINDIGLSGFRQEAICLVKGSHKTLKLVVK--RKNEVS CAVPO126_2_PE3 NOISO LQIEEGSKAAAVDKLLAGDEIVGINDIGLSGFRQEAICLVKGSHKTLKLVVK--RRNDVS CHICK1_PE2106 NOISO -------------------------TLFLSVFRRNDLACRPHSWHATKFT---------- DANRE11_47_PE9 NOISO --------------------MVDIVTQTMP--AESDVHVARNFLTKILRSSM--RRNESS DANRE6_32_PE4 NOISO ---------------------------------------------SLPLAAH--RRNEPM ECHTEGS_4788_PE1 NOISO --IEEGSKAAAVDSLLAGDEIVGINGVGLSGFRQEAICLVKGSHKTLRLVVK--RKNELS FELCAGS_2696_PE1 NOISO --IEEGSKAAAVDKLLAGDEIVGINDIGLSGFRQEAICLVKGSHKTLKLVVK--RKNELS FUGRU13_1_PE137 ISOFORMIN TKVEEGSKAAAVN-LQVGDELVNINEVPLSGYRQEAICLVKGSHKTLSLVVK--RRNDPI FUGRU13_1_PE138 ISOFORMIN TKVEEGSKAAAVN-LQVGDELVNINEVPLSGYRQEAICLVKGSHKTLSLVVK--RRNDPI FUGRU13_1_PE139 ENSTRUG00000012349 TKVEEGSKAAAVN-LQVGDELVNINEVPLSGYRQEAICLVKGSHKTLSLVVK--RRNDPI FUGRU13_1_PE140 ISOFORMIN ------------------------------------------------------------ FUGRU57_1_PE17 NOISO TKVEEGSVAAAVC-LQAGDEMVSVNAVPLSGSRQEAISLVKSSHKKLTLVVR--RKNDPV GASACGROUPI_29_PE25 NOISO TKVERGSVAAADE--------------------QEAVRLVR-SRSALSLLVR--RKNDPN GASACGROUPVIII_19_PE38 NOISO TKVEEGSKASAVS-LQAGDELVNINEIPLSGFRQEAICLVKGSHKTLSLVVK--RRSEPI GORGOX_11_PE1 NOISO TKIEEGSKAAAVDKLLAGDEIVGINDIGLSGFRQEAICLVKGSHKTLKLVVK--RRSELG HORSEX_7_PE4 ISOFORMIN -QIEEGSKAAAVDKLLAGDEIVGINDIGLSGFRQEAICLVKGSHKTLKLVVK--RRNELS HORSEX_7_PE5 ENSECAG00000012150 -QIEEGSKAAAVDKLLAGDEIVGINDIGLSGFRQEAICLVKGSHKTLKLVVK--RRNELS HSX_PE143 ENSG00000146950 TKIEEGSKAAAVDKLLAGDEIVGINDIGLSGFRQEAICLVKGSHKTLKLVVK--RRSELG LOXAF94_6_PE2 NOISO LQIEEGSKAAAVDKLLAGDEIVGINDIGLSGFRQEAICLVKGSHKTLKLVVK--RRSELS MACEUGS_5635_PE1 NOISO --IEEGSKAAAVDKLLAGDEIVGINDIGLSGFRQEAICLVKGSHKTLKLVVK--XXXXXX MACMUX_8_PE9 ENSMMUG00000006193 NKIEEGSKAAAVDKLLAGDEIVGINDIGLSGFRQEAICLVKGSHKTLKLVVK--RRSELG MICMUGS_799_PE3 NOISO --IEEGSKAAAVDKLLAGDEIVGINDIGLSGFRQEAICLVKGSHKTLKLVVK--RKSELS MONDO7_34_PE7 ENSMODG00000017449 ------------------------------------------------LFFS--RRNDVG MONDO7_34_PE8 ISOFORMIN ------------------------------------------------------------ MOUSEX_PE1950 ISOFORMIN TKIEEGSKAAAVDKLLAGDEIVAINDVSLSGFRQEAICLVKGSHKTLKLVVK--RKSDPS MOUSEX_PE1951 ENSMUSG00000045180 TKIEEGSKAAAVDKLLAGDEIVAINDVSLSGFRQEAICLVKGSHKTLKLVVK--RKSDPS MYOLUGS_3236_PE1 NOISO TKVEEGSKAAAVDKLLAGDEIVGINDIGLSGFRQEAICLVKGSHKTLKLVVK--RRNELS ORNANULTRA462_6_PE4 ENSOANG00000009689 -QIEEGSKAAAVDKLLAGDEIISINDRGLSGFRQEAICLVKGSHKTLKLIVK--RRNETS ORNANULTRA462_6_PE5 ISOFORMIN -QIEEGSKAAAVDKLLAGDEIISINDRGLSGFRQEAICLVKGSHKTLKLIVK--RRNETS ORYLA2_17_PE12 NOISO TKVEQGSAAAAAR-LQAGDEMVSVNAVPLNGSRLEAISLVKSSHQTLTLVIR--RKNEAV ORYLA4_32_PE17 NOISO TKVEEGSKAAAVS-LQVGDELVNINQIPLSGYRQEAICLVKGSHKTLTLVVR--RRNEPV OTOGAGS_2886_PE1 NOISO --TEEESKAAAVDGLLYKKNNETSHDNGLSGIRYFARGLTQTSHRALKK--E--KKSDPS PANTRX_11_PE1 NOISO --IEEGSKAAAVDKLLAGDEIVGINDIGLSGFRQEAICLVKGSHKTLKLVVK--RRSELG PIGX_6_PE3 NOISO ------------------------------------------------------------ POEGU1_20_PE6 NOISO -----------------------------VVFRRNDLACRPHSWHATKFT---------- PONPYX_10_PE2 NOISO TKIEEGSKAAAVDKLLAGDEIIGINDIGLSGFRQEAICLVKGSHKTLKLVVK--RRSELG PTEVAGS_2083_PE1 NOISO --IEEGSKAAAVDKLLAGDEIVGINDVGLSGFRQEAICLVKGSHKSLKLVVK--RKNELN RATX_PE414 ENSRNOG00000024322 TKIEEGSKAASVDKLLAGDEIVAINDVTLSGFRQEAICLVKGSHKTLKLVVK--RKSDPS RATX_PE415 ISOFORMIN ------------------------------------------------------------ SPETRGS_3166_PE1 NOISO --IEEGSKAAAVDRLLAADEIVGIND-GLSGFRQEAILSVEGSHRTLKLVVK--XRSELS TARSYGS_4663_PE1 NOISO --IEEGSKAAAVDKLLAGDEIVGINGIGLSGFRQEAICLVKGSHKTLQLVVK--RRSELS TETNG3_PE72 ENSTNIG00000017158 TKVEEGSAAATVC-LRAGDEMVSVNAVRLSGSRQEAISLVKSSHRTLTLVVR--RKNDPV TETNG3_PE73 ISOFORMIN TKVEEGSAAATVC-LRAGDEMVSVNAVRLSGSRQEAISLVKSSHRTLTLVVR--RKNDPV TURTRGS_550_PE3 NOISO TKIEEGSKAAAVDKLLAGDEI-GINDXXXXXXXXXXXXXXXXXXXXXXXXXX--XRTELS MATCH CONSENSUS ??????????????????????????????????????????S?????????????????

AILMEGL194998_1_PE1 NOISO WRPHSWHATKFSDSHPETSASPFPSASACPSWHSRHHAS--SSSHDLSG-TWERTNLQRT ANOCA81_2_PE4 NOISO ------------------------------------------------------------ BOVINX_88_PE9 NOISO WRPHSWHATKFSDSQSEPAAPLL----PCPSRPSRYHAS--SSSQDLSGGAWEPANLQRT CALJAX_9_PE1 ENSCJAG00000000928 WRPHSWHATKFSDSHRELAASPFPSASSCPSWSSRHHAS--SSSHDLSS-SWEQTNLQQT CALJAX_9_PE2 ISOFORMIN WRPHSWHATKFSDSHRELAASPFPSASSCPSWSSRHHAS--SSSHDLSS-SWEQTNLQQT CANFAX_7_PE3 NOISO WRPHSWHATKFSDNHPETSASPFPSASACPSWHSRQLTS--SSSHDLSG-TWEHTNLQRT CAVPO126_2_PE3 NOISO WRPHSWHATKFSDDHPEPAASQFPSTSGCSSWHGCHHTT--SSSQDLSS-SWEQRNLQRT CHICK1_PE2106 NOISO ------------ESQPETATSHLPSSNACTSWHSRYHAS--CSSHDLSN-SWDQSSLHRA DANRE11_47_PE9 NOISO CRPHSWHSAKSSESSNPNDSKSEPNPAPDPTWQTKCDPG--SPTKEFTS-CWGQTNLRQA DANRE6_32_PE4 NOISO SRPHSWHATKFNETHSEAKTQS----TPSPVWQTRYDAS--SFSSELST-GWDQTNLRRV ECHTEGS_4788_PE1 NOISO WRPHSWHATKFSDGAPESMATPFSAAGTCPSWHVRHHVS--SSSHDLSG-TWEQTNLQRT FELCAGS_2696_PE1 NOISO WRPHSWHATKFSDSHPDTSASPFPSASSCPSWHGRPHPS--SSSHDLSG-TWEHTNLQRT FUGRU13_1_PE137 ISOFORMIN SRPHSWHATKFNENQSDAAKTQ---SPPMPVWQTRYDASCSSSSTDLSS-SWELTNLRRA FUGRU13_1_PE138 ISOFORMIN SRPHSWHATKFNENQSDAAKTQ---SPPMPVWQTSFFSRCSSSSTDLSS-SWELTNLRRA FUGRU13_1_PE139 ENSTRUG00000012349 SRPHSWHATKFNENQSDAAKTQ---SPPMPVWQTRYDASCSSSSTDLSS-SWELTNLRRA FUGRU13_1_PE140 ISOFORMIN ---------------------I---VSSCFCRRVSFFSRCSSSSTDLSS-SWELTNLRRA FUGRU57_1_PE17 NOISO SRPNSWYSAKLTEEELEPAKRE---ATAAPVWPPNNETR--PK--DSSN-RRDQDSHQQL GASACGROUPI_29_PE25 NOISO SRPHSWHASKLTEEESEAAVRD---AAAARVWQPKHDAR--PN--ETPS-RGDQSSQCPL GASACGROUPVIII_19_PE38 NOISO SRPHSWHATKFNESQSQTAKAQ---SPPTQVWQTRYDAS--SSSTDLSS-AWEQTDLRRA GORGOX_11_PE1 NOISO WRPHSWHATKFSDSHPELAASPFTSTSGCPSWSGRHHAS--SSSHDLSS-SWEQTNLQRT HORSEX_7_PE4 ISOFORMIN WRPHSWHATKFSESHPETSASQFS-TSVYPSWHGRHHAS--SSSHDLSG-TWEQTNLQRT HORSEX_7_PE5 ENSECAG00000012150 WRPHSWHATKFSESHPETSASQFS-TSVYPSWHGRHHAS--SSSHDLSG-TWEQTNLQRT HSX_PE143 ENSG00000146950 WRPHSWHATKFSDSHPELAASPFTSTSGCPSWSGRHHAS--SSSHDLSS-SWEQTNLQRT LOXAF94_6_PE2 NOISO WRPHSWHATKFCDGAPEAVAIPFSTAGTCPSWHTRQHAS--SSSHDLSG-TWEQTNLQRT MACEUGS_5635_PE1 NOISO XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--SSSHDLSS-SWDQTNLLRT MACMUX_8_PE9 ENSMMUG00000006193 WRPHSWHATKFSDSHPELAASPFPSASGCPSWSGRHHAS--SSSHDLSS-SWEQTNLQRT MICMUGS_799_PE3 NOISO WRPHSWHATKFSDSHVEPAASLFPSASGCPSWHGRHHAS--SS-HDL-S-SWEQTXXXXX MONDO7_34_PE7 ENSMODG00000017449 CRPHSWHATKFTESHPETVSSQ---SNVCTSWHTRYHAS--SSSHDLSS-SWDQTNLHRT MONDO7_34_PE8 ISOFORMIN -------------------------------------SS--SSSHDLSS-SWDQTNLHRT MOUSEX_PE1950 ISOFORMIN WRPHSWHATKYFDVHPEPAASLFLNTSGSPSWKSQHQAS--SSSHDLSG-SWEHTSLQRT MOUSEX_PE1951 ENSMUSG00000045180 WRPHSWHATKYFDVHPEPAASLFLNTSGSPSWKSQHQAS--SSSHDLSG-SWEHTSLQRT MYOLUGS_3236_PE1 NOISO WRPHSWHATKFSDSHPETPTCQLSSAGACPSWHGRHHAS--ASSQDLSG-VWEPTSLQRT ORNANULTRA462_6_PE4 ENSOANG00000009689 CRPHSWHATKFTDSHPDPGAAQQVSVNTCTSWHSRYHSS--SSSHDLSS-SWDQTNLHRT ORNANULTRA462_6_PE5 ISOFORMIN CRPHSWHATKFTDSHPDPGAAQQVSVNTCTSWHSRYHSS--SSSHDLSS-SWDQTNLHRT ORYLA2_17_PE12 NOISO SRPHSWHSSKLTEEESEPARSE---ANPAPIWQPKHERE--HVNRELSA-TADQSPVHQD ORYLA4_32_PE17 NOISO SRPHSWHSTKFNENQSESSKTQ---SPPTAVWHCKYDAS--SSDNDLSG-GWEQTNLCRA OTOGAGS_2886_PE1 NOISO WRPHSWHATKCSDSHVEPAASLFPSASGGPSWHSRHHAS--SSSHDLSS-SWEQTTLQRA PANTRX_11_PE1 NOISO WRPHSWHATKFSDSHPELAASPFTSTSSCPSWSGRHHAS--SSSHDLSS-SWEQTNLQRT PIGX_6_PE3 NOISO -------------------------------------SS--SSSQDLSGSAWEQTNLQRA POEGU1_20_PE6 NOISO ------------ESQPEAATSHLPS-HACASWHSSYHAS--CSSHDLSN-SWDQSSLYRT PONPYX_10_PE2 NOISO WRPHSWHATKFSDSHPELVASPFTSTSGCPSWSGRHHAS--SSSHDLSS-SWEQTNLQRT PTEVAGS_2083_PE1 NOISO WRPHSWHAVKFSDDHPDTIAAQFSSASDCPPRHGRHHTS--SSSQDLSG-TWEQTNLQQA RATX_PE414 ENSRNOG00000024322 WRPHSWHATKYFDVHPEPPVSLFLNSSSSPSWKSQHQAS--SSSHDLSG-SWEHTSLQRT RATX_PE415 ISOFORMIN ---------------------MRPSTVTSRIWWS-ESSS--SSSHDLSG-SWEHTSLQRT SPETRGS_3166_PE1 NOISO WRPHSWHATKFSDGHPEPVSSQFPAASGCPSWHSRHHAS--SSSHDLSG-SWEQTNLQRT TARSYGS_4663_PE1 NOISO WRPHSWHATKFSDSHPEMAASPFPSAIG-PSWQGRHHAS--SSSHDLSG-TWEQTNLQRT TETNG3_PE72 ENSTNIG00000017158 SRPHSWYSSKLTEEEPESAKRG---ATAAPVWQPQHETK--PK--ESPK-HGDQDSRQQL TETNG3_PE73 ISOFORMIN SRPHSWYSSKLTEEEPESAKRG---ATAAPVWQPQHETK--PK--ESPK-HGDQDSRQQL TURTRGS_550_PE3 NOISO WRPHSWHVTKFSDSHPETSASPFPSTSSCPLWPGQXXXX--SSSQDLSSGLWEQTHLQRA MATCH CONSENSUS ?RPHSW???K?????????????????????W?????????SSS?DLS???W????L???

AILMEGL194998_1_PE1 NOISO SDHFSSLGSVDSLDQPSQPYPSGRLSAAKSNS-SIDHLG-GQSKRDSAYGSFSTSSSTPD ANOCA81_2_PE4 NOISO ------------------------------------------------------------ BOVINX_88_PE9 NOISO SDHFSSLGSVDSLDPSSQPDPSGRLSAAKSSS-SIDRLG-GASKRDSAYGSFSTRSSTPD CALJAX_9_PE1 ENSCJAG00000000928 LDHFSSLGSVDSLDH-----PSDRLSAAKSNS-SIDHLG-AHSKHDSAYGSFSTSSSTPD CALJAX_9_PE2 ISOFORMIN LDHFSSLGSVDSLDH-----PSDRLSAAKSNS-SIDHLG-AHSKHDSAYGSFSTSSSTPD CANFAX_7_PE3 NOISO SDHFSSLGSVDSLDQPSQPYPSGRLSAAKSNS-SIDHLG-GQSKRDSAYGSFSTSSSTPD CAVPO126_2_PE3 NOISO SDHFSSLGSVDSLDHPSQPSPSGHLLAAKSNS-SINHLG-GPNQRDSAYGSFSTSSGTPD CHICK1_PE2106 NOISO SDQFSSLGSMDSWDQTPQVAQYGRLSSARSNS-SIDHLG-SQNKRDSAYGSFSTSSSTPD DANRE11_47_PE9 NOISO SCQFSSVRNMESVEPSSHAFSKEQPLTSKPNG-GADHEV-LESAISKPALPGNAFSGTAD DANRE6_32_PE4 NOISO SDQFSSLGSMDSLEHSSHPYPPGRLSPNKSNNNSIEHLG--SGKRDSAYSSFSTSSGTPD ECHTEGS_4788_PE1 NOISO SDHFSSLGSVDSLDPPAQPCPSGRLSAAKSNS-SIDHLG-GPSKRDSAYGSFSTSSSTPD FELCAGS_2696_PE1 NOISO SDHFSSLGSVDSLDHPSQPYPSGRLSAARSNG-SIDHLG-GPSKRDSAYGSFSTSSSTPD FUGRU13_1_PE137 ISOFORMIN SDQFSSLGSMDSLEQASHPYPAGQLSPTKSNS-SIDHLG--GGKRDSAYSSFSTSSGTPD FUGRU13_1_PE138 ISOFORMIN SDQFSSLGSMDSLEQASHPYPAGQLSPTKSNS-SIDHLG--GGKRDSAYSSFSTSSGTPD FUGRU13_1_PE139 ENSTRUG00000012349 SDQFSSLGSMDSLEQASHPYPAGQLSPTKSNS-SIDHLG--GGKRDSAYSSFSTSSGTPD FUGRU13_1_PE140 ISOFORMIN SDQFSSLGSMDSLEQASHPYPAGQLSPTKSNS-SIDHLG--GGKRDSAYSSFSTSSGTPD FUGRU57_1_PE17 NOISO TSQPSSLNNMERLEHPSALYPTGHISPTKYIG-STEPFCGLGGKKDATLSCFPTGSSSPG GASACGROUPI_29_PE25 NOISO TSQLSPGTNMEKLERPSHPFPSQ--------C-SAQPLCGPEGKRDSAFSCFSIASSPPG GASACGROUPVIII_19_PE38 NOISO SDQFSSLGSMDSLEHVSHPYAAGQLSPAKSNN-SMEHLG--GGKRDSAYSSFSTSSGTPD GORGOX_11_PE1 NOISO LDHFSSLGSVDSLDH-----PSGRLSVAKSNS-SIDHLG-SHSKRDSAYGSFSTSSSTPD HORSEX_7_PE4 ISOFORMIN SDHFSSLGSVDSLDHPCQPYSSGCLSAAKSNS-SIDRLG-GPNQRDSAYGSFSTSSSTPD HORSEX_7_PE5 ENSECAG00000012150 SDHFSSLGSVDSLDHPCQPYSSGCLSAAKSNS-SIDRLG-GPNQRDSAYGSFSTSSSTPD HSX_PE143 ENSG00000146950 LDHFSSLGSVDSLDH-----PSSRLSVAKSNS-SIDHLG-SHSKRDSAYGSFSTSSSTPD LOXAF94_6_PE2 NOISO SDHFSSLGSVDSLDPPTQPYSSGRLSAAKSSS-SIDHLS-GSNKRDSAYGSFSTSSSTPD MACEUGS_5635_PE1 NOISO SDQFSSLGSMDSLDHPSQPYSYGRLSAAKSNS-SIDHLG-NPNKRDSAYGSFSTTSSTPD MACMUX_8_PE9 ENSMMUG00000006193 LDHFSSLGSVGSLDH-----PSSRLSVAKSNS-SIDHLG-SHSKRDSAYGSFSTSSSTPD MICMUGS_799_PE3 NOISO XXXXXXXXXXXXXXXXX--XXXXXXXXXXXXX-XXXXXX-XX----XXXXXXXXXXXXXX MONDO7_34_PE7 ENSMODG00000017449 SDQFSSLGSMDSLDHPSQPYSYGRLSAAKSNS-SIDHLG-HPSKRDSAYGSFSTTSSTPD MONDO7_34_PE8 ISOFORMIN SDQFSSLGSMDSLDHPSQPYSYGRLSAAKSNS-SIDHLG-HPSKRDSAYGSFSTTSSTPD MOUSEX_PE1950 ISOFORMIN SDHFSSMGSIDSLDHSSQLYPSGHLSSAKSNS-SIDHLG-GHSKRDSAYGSFSTCSSTPD MOUSEX_PE1951 ENSMUSG00000045180 SDHFSSMGSIDSLDHSSQLYPSGHLSSAKSNS-SIDHLG-GHSKRDSAYGSFSTCSSTPD MYOLUGS_3236_PE1 NOISO SDHFSSLGSVDSLDQPSQPSPSGRLSAAKSSG-SIDHLG-GPSKRDSAYGSFCTSSSTPD ORNANULTRA462_6_PE4 ENSOANG00000009689 SDHFSSLGSMDSLGHPSQPYAYGRLSATKSNS-SIDRLS-HQNQRDSAYGSFSLNSGTPN ORNANULTRA462_6_PE5 ISOFORMIN SDHFSSLGSMDSLGHPSQPYAYGRLSATKSNS-SIDRLS-HQNQRDSAYGSFSLNSGTPN ORYLA2_17_PE12 NOISO SSPTSSVNSMERVECPAHLFPPGHLSPPKY-G-SAEPLGG--ARRDSPFSCFSSGSSPPI ORYLA4_32_PE17 NOISO SDQFSSLGSMDSLEHVS-----------QSNN-SMEHLG--GGKRDSAYSSFSTSSSTPD OTOGAGS_2886_PE1 NOISO SGHFSSLGSMDSLDHPSQSYPSGRLSAAKSNS-SIDHLG-SHSQRDSAYGSFSTSSGTPD PANTRX_11_PE1 NOISO LDHFSSLGSVDSLDH-----PSGRLSVAKSNS-SIDHLG-SHSKRDSAYGSFSTSSSTPD PIGX_6_PE3 NOISO SGHFSSLGSVDSLDQPAQSSPSGRLSAAKSNS-SIDHLG-GPSKRDSAYGSFSTSSSTPD POEGU1_20_PE6 NOISO SDQFSSLGSMDSWDHTPQVAQYGRLSSARSNS-SIDHLG-SQSKRDSAYGSFSTSSSTPD PONPYX_10_PE2 NOISO LDHFSSLGSVDSLDH-----PSGRLSVAKSNS-SIDHLG-SHSKRDSAYGSFSTSSSTPD PTEVAGS_2083_PE1 NOISO SDQFSSLGSVDSLDH-----PSGCLSAAKSNS-SIDRLG-GSNKRDSAYSSFSTGSGTPD RATX_PE414 ENSRNOG00000024322 SDHFSSMGSIDSLDHSSQLYPSGHLSSAKSNS-SIDHLG-GHSKRDSAYGSFSTCSSTPD RATX_PE415 ISOFORMIN SDHFSSMGSIDSLDHSSQLYPSGHLSSAKSNS-SIDHLG-GHSKRDSAYGSFSTCSSTPD SPETRGS_3166_PE1 NOISO SDHFSSLGSVDSLDHSS--QPSGRLSAAKSNS-SIDHLS-SHSKRDSAYGSFSTSSSTPD TARSYGS_4663_PE1 NOISO SDHFSSLGSVDSLDH-----PSGRLSAAKSNS-SIDHLG-GHSKRDSAYGSFSTSSSTPD TETNG3_PE72 ENSTNIG00000017158 SSQIGSVKNMERLEPPALLYPAGHISPTEYIS-SAEPFCGLAGKKDAGLSCFSTGSSPPG TETNG3_PE73 ISOFORMIN SSQIGSVKNMERLEPPALLYPAGHISPTEYIS-SAEPFCGLAGKKDAGLSCFSTGSSPPG TURTRGS_550_PE3 NOISO SDHFSSLGSVDSLDQPAQSYPSGRLSAAKSNS-SIDHLG-GPSKRDSAYGSFSTSSSTPD MATCH CONSENSUS ???FSS?GS?DSL?????????G?LS??KS???S???L??????RDSAY?SFST?S?TPD

AILMEGL194998_1_PE1 NOISO HTLPKA--DASSAENILYKVGLWEASRPGSSRQ-GQAASDPQGLEERLGHFPA-RVPCDS ANOCA81_2_PE4 NOISO ------------------------------------------------------------ BOVINX_88_PE9 NOISO HTLPKA--DASSAENILYKVGLWEASAAADRRP-GLAAGDPQGTEEPLGCFPP-RVP--- CALJAX_9_PE1 ENSCJAG00000000928 HTLAKA--DTSSAENILYSVGLWEAPRQGG-RQ-AQASGDPQGLEDKPRCFPP-RVPSDS CALJAX_9_PE2 ISOFORMIN HTLAKA--DTSSAENILYSVGLWEAPRQGG-RQ-AQASGDPQGLEDKPRCFPP-RVPSDS CANFAX_7_PE3 NOISO HTLPKA--DASSAENILYKVGLWEASKPASSRQ-AQAASDPQGLEERLGYFPP-RVPCES CAVPO126_2_PE3 NOISO HTLPKA--EASSVENILHKVGLWEAA--------------PQALEERPSTFLS-RAPGDS CHICK1_PE2106 NOISO HTLSNA--DTSSTENMLYKVGHWETSKYGNK--SGQFLNDYSGIEDKPGYLPA-PIQYEN DANRE11_47_PE9 NOISO HGAPR---GANPTEGVFYRG-------------------DLTVPSDCHRYLQI-PIGNGG DANRE6_32_PE4 NOISO YTLSKS--NTASTENMLYKINQWDSSARHSNGRHSQNLSEGVRQDERPGYLHH-LSSTGN ECHTEGS_4788_PE1 NOISO HTLPRA--DGSSTENLLYKVGLWEAPRQGNRHP-SLSGDLTHGLEERLAHLPA-GHHHES FELCAGS_2696_PE1 NOISO HTLTKA--DASSAENILYNVGLGEASRPGG-RQ-GQAASDPQGLEDRLGYFPP-RVPRDG FUGRU13_1_PE137 ISOFORMIN YTISKS--NAASTENMLHKFSQWDSGGKSNNGRNG----Q----DERSTFSHV-PAVGSG FUGRU13_1_PE138 ISOFORMIN YTISKS--NAASTENMLHKFSQWDSGGKSNNGRNG----Q----DERSTFSHV-PAVGSG FUGRU13_1_PE139 ENSTRUG00000012349 YTISKS--NAASTENMLHKFSQWDSGGKSNNGRNG----Q----DERSTFSHV-PAVGSG FUGRU13_1_PE140 ISOFORMIN YTISKS--NAASTENMLHKFSQWDSGGKSNNGRNG----Q----DERSTFSHV-PAVGSG FUGRU57_1_PE17 NOISO LEASPIGWKGTSSENIFYKGLQNE----------------GSQAAERPRYLQP-TMGNG- GASACGROUPI_29_PE25 NOISO HDHRASDRKGTSTENIFFKGLYGE----------------GPQPAERPRYTCE-----G- GASACGROUPVIII_19_PE38 NOISO YTLSKS--DAASTENMLYKVGQWDAGGKQSNGRSA----QSA-ADERVAYIQV-PGVGAG GORGOX_11_PE1 NOISO HTLSKA--DTSSAENILYTVGLWEAPRQGG-RQ-AQAAGDTQGSEEKLRCFPP-RVPGDS HORSEX_7_PE4 ISOFORMIN HTLPKA--DASSTENILYKVGLWEASKPGSSRQ-GQAAGDPQGLEDRLGYFPP-RVLCDS HORSEX_7_PE5 ENSECAG00000012150 HTLPKA--DASSTENILYKVGLWEASKPGSSRQ-GQAAGDPQGLEDRLGYFPP-RVLCDS HSX_PE143 ENSG00000146950 HTLSKA--DTSSAENILYTVGLWEAPRQGG-RQ-AQAAGDPQGSEEKLSCFPP-RVPGDS LOXAF94_6_PE2 NOISO HTLPRA--DGSSTENLLYKVGLWESCRPGGRQG-QVGGELTHGLEERLSYMPT-GPHHES MACEUGS_5635_PE1 NOISO HTLSKA--DASSTENMLYKVGLWDSAKPGTSKQVQSFSDNVQSLEERLGCLPS-TLHYEN MACMUX_8_PE9 ENSMMUG00000006193 HTLSKA--DTSSAENILYSVGLWEAPRQGG-RQ-AQAAGDPQGLEEKLRCFPP-RVPSDS MICMUGS_799_PE3 NOISO XXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXX-XXAASVPQCLEDRLECFPP-RVRGDS MONDO7_34_PE7 ENSMODG00000017449 HTLSKA--DASSTENMLYKVGLWDSAKSGTSKQSLPFGDNTQSLEERLGCLPS-ALQYES MONDO7_34_PE8 ISOFORMIN HTLSKA--DASSTENMLYKVGLWDSAKSGTSKQSLPFGDNTQSLEERLGCLPS-ALQYES MOUSEX_PE1950 ISOFORMIN HTLPKA--DASSTENILYKVGLWEASRPGSSRQ-SQSTGDPQGLQDRPSCFIP-RVPGNS MOUSEX_PE1951 ENSMUSG00000045180 HTLPKA--DASSTENILYKVGLWEASRPGSSRQ-SQSTGDPQGLQDRPSCFIP-RVPGNS MYOLUGS_3236_PE1 NOISO HTLPKA--DASSTDNILYKVGLWEASRPGGR-------QDPQGLEERPGGFPP-RGPLDS ORNANULTRA462_6_PE4 ENSOANG00000009689 HTLSKT--DATSTENVLYKVAQWDSARSGNGKPLQALGDNAPSGGERLASWPP-PVPWEL ORNANULTRA462_6_PE5 ISOFORMIN HTLSKT--DATSTENVLYKVAQWDSARSGNGKPLQALGDNAPSGGERLASWPP-PVPWEL ORYLA2_17_PE12 NOISO NDSSSAGRRGTSTESIFFKGFQGD----------------GAEPGDRLRVLHS-AGWNG- ORYLA4_32_PE17 NOISO YTLSKS--NAASTENMLYKVTQWDAGGRRGQGAAA----DGVKLEDRLPYFQM-PGVGPG OTOGAGS_2886_PE1 NOISO HTLSKA--DASSAESIPYSVGLWEASRQGRSRH-GQATSDPPGLEERLGCFPP-RVPGDN PANTRX_11_PE1 NOISO HTLSKA--DTSSAENILYTVGLWEAPRQGG-RQ-AQAAGDPQGSEEKLRCFPP-RVPGDS PIGX_6_PE3 NOISO HTLPKA--DASSAENILYKVGLWEASAAGGGRQ-GLTAGDPQGVEERLGCFPP-RVPCDS POEGU1_20_PE6 NOISO HTLSSA--DTSSTENMLYKVGPWETAKHGSK--SGQFLNDSSGTEDKPGYLPA-PIQYEN PONPYX_10_PE2 NOISO HTLSKA--DTSSAENILYTVGLWEAPRQGG-RQ-AQAAGDPQGSEEKLRCFPP-RVPSDS PTEVAGS_2083_PE1 NOISO HALPKA--DASSTENIVSKVGLWEASRRAA--------GDAQGPEEKLRYSPP-RVPCDS RATX_PE414 ENSRNOG00000024322 HTLPKA--DASSTENILYKVGLWEASRPGSSRQ-SQSTGDPQGLQDRPSSFLP-RVPGNS RATX_PE415 ISOFORMIN HTLPKA--DASSTENILYKVGLWEASRPGSSRQ-SQSTGDPQGLQDRPSSFLP-RVPGNS SPETRGS_3166_PE1 NOISO HTLPKA--DASSAENILYKVGLWEASRHSS-RQ-GQAMSDPQVPEDRSLCFPA-RIPNDS TARSYGS_4663_PE1 NOISO HTLSKA--DTSSAENILYSVGLWEAPRQGGSRQ-GQAAGDPQGLEDRFGCFPPPRVSSDS TETNG3_PE72 ENSTNIG00000017158 LDSSPVGWKGTSAESMFFKGPQKE----------------CSQAAERPRYLQP-PLGSG- TETNG3_PE73 ISOFORMIN LDSSPVGWKGTSAESMFFKGPQKE----------------CSQAAERPRYLQP-PLGSG- TURTRGS_550_PE3 NOISO HTLPKA--DASSAENIIYKVGLWEASRDRQXXXXXXXXXXXXXXXXXXXXXXX-XXXXXX MATCH CONSENSUS ?T?????????S?EN???????W?????????????????????????????????????

AILMEGL194998_1_PE1 NOISO SRSPRPEDSPEAKLA-TSGRPNFGPVWYVPDKKKA-PSSP-PPPPPPLRSDSFA-ATKSH ANOCA81_2_PE4 NOISO ------------------------------------------------------------ BOVINX_88_PE9 NOISO ------EDGPEPKLA-ACGRSSSGPVWYVPDKRRA-PPSP-PPPPPPLRRDSFA-ATRIH CALJAX_9_PE1 ENSCJAG00000000928 GKGPRPEYNVEPKLA-APGRSNFGPVWYVPDKKKA-PSSP-PPPLPPLRSDSFA-ATKSH CALJAX_9_PE2 ISOFORMIN GKGPRPEYNVEPKLA-APGRSNFGPVWYVPDKKKA-PSSP-PPPLPPLRSDSFA-ATKSH CANFAX_7_PE3 NOISO SKSPRPEDSPEAKLA-ASGRSNFGPVWYIPDKKKA-PSSP-PPPPPPLRSDSFA-ATKSH CAVPO126_2_PE3 NOISO SKSPRPEDTVEPKLT-ASSRSSFGPIWHVPDKKKA-PPSP-PPPAPPLRSDSFA-ATKNH CHICK1_PE2106 NOISO NRSPRIEEHPDVKLS-GSGRSSFGPVWYVPDKRKS--SSP-PPPPPPLRSDSFA-ATKGH DANRE11_47_PE9 NOISO RVSPSVEEQSSSRLS-STARSNHRPVWHIPENKMSSSE---APPAPPLRSDSFT-ATRVH DANRE6_32_PE4 NOISO HEIPRAEELPGNRHS-SSGRVNIGPVWHVPDMKKNMISST-PPPTPPTRSDSFA-ATKVH ECHTEGS_4788_PE1 NOISO SKSPRQEGSPEPKA---PARSNFGPIWYVPDKKKA-PASP-PPPPPPLRSDSFA-ATKGR FELCAGS_2696_PE1 NOISO SRSPRPEDSPETKLA-TPGKSNLGPVWYVPDKRKA-PSSP-PPPPPPLRSDSFA-ATKSH FUGRU13_1_PE137 ISOFORMIN WEAPQTED--SSRHS-TSSRTSFGPVWHVPEKKKSAGPSPSPPPPPPARSDSFA-ATRVH FUGRU13_1_PE138 ISOFORMIN WEAPQTED--SSRHS-TSSRTSFGPVWHVPEKKKSAGPSPSPPPPPPARSDSFA-ATRVH FUGRU13_1_PE139 ENSTRUG00000012349 WEAPQTED--SSRHS-TSSRTSFGPVWHVPEKKKSAGPSPSPPPPPPARSDSFA-ATRVH FUGRU13_1_PE140 ISOFORMIN WEAPQTED--SSRHS-TSSRTSFGPVWHVPEKKKSAGPSPSPPPPPPARSDSFA-ATRVH FUGRU57_1_PE17 NOISO ---GWEGEQP-SRVS-VAVRPHVGPVWQVPENKK-DPS---PPPPPPLRSDSFA-VTKVF GASACGROUPI_29_PE25 NOISO ---SRGEEQPASRCS-FAGRSGVGLQGKVPEKKKS-QS---PPPQPPLRSDSFA-ASKVF GASACGROUPVIII_19_PE38 NOISO ---PQADDSAGSRHS-TSSRTTVGPVWHVPEAKKKASSS----PPSPARSDSFA-ATKVH GORGOX_11_PE1 NOISO GKGPRPEYNAEPKLA-APGRSNFGPVWYVPDKKKV-PSSP-PPPPPPLRSDSFA-ATKSQ HORSEX_7_PE4 ISOFORMIN SKSPRPDDSPEPKVA-SSGRSSFGPVWYVPDKKKA-PSSP-PPPPPPLRSDSFA-ATKSH HORSEX_7_PE5 ENSECAG00000012150 SKSPRPDDSPEPKVA-SSGRSSFGPVWYVPDKKKA-PSSP-PPPPPPLRSDSFA-ATKSH HSX_PE143 ENSG00000146950 GKGPRPEYNAEPKLA-APGRSNFGPVWYVPDKKKA-PSSP-PPPPPPLRSDSFA-ATKSH LOXAF94_6_PE2 NOISO GKSPRREDSPEPKLAACMGKSNFGPVWYVPDKKM--------------RSDSFA-ATKGH MACEUGS_5635_PE1 NOISO NRSPRLEENTDPKLV-NSGRSSFGPVWYVPDKKKA-SSSP-PPPPPPLRSDSFA-ATKSH MACMUX_8_PE9 ENSMMUG00000006193 DKGPRPEYNAEPKLA-VPGRSNFGPVWYVPDKKKA-P----------ARSDSFA-ATKSH MICMUGS_799_PE3 NOISO SKRSRPEDSAELNPA-SSARTNFGPVWYVPDKKKA-PSSP-P-PPTPLRSDSFA-ATKSH MONDO7_34_PE7 ENSMODG00000017449 RRSPRLEEIPDPKLA-TSGRSSFGPVWYVPDKKKP-SSSP-PPPPPPLRSDSFA-ATKSH MONDO7_34_PE8 ISOFORMIN RRSPRLEEIPDPKLA-TSGRSSFGPVWYVPDKKKP-SSSP-PPPPPPLRSDSFA-ATKSH MOUSEX_PE1950 ISOFORMIN SKSPRPEDNVEPKIA-THGRSNFGPVWYVPDKKKA-PS-P-PPLGLPLRSDSFSVAARGH MOUSEX_PE1951 ENSMUSG00000045180 SKSPRPEDNVEPKIA-THGRSNFGPVWYVPDKKKA-PS-P-PPLGLPLRSDSFSVAARGH MYOLUGS_3236_PE1 NOISO SRSPRPEDVPEPKLA-TSGRSSFGPIWHVPDKKRA-PPSP-PPPPPPLRSDSFA-ATKSH ORNANULTRA462_6_PE4 ENSOANG00000009689 SNSPRPDDIPEPRFS-GSGRSNFGPVWYVPEKKRT-SRSP-PPPPPPLRSDSFA-ATKGL ORNANULTRA462_6_PE5 ISOFORMIN SNSPRPDDIPEPRFS-GSGRSNFGPVWYVPEKKRT-SRSP-PPPPPPLRSDSFA-ATKGL ORYLA2_17_PE12 NOISO ---SRGEGQPACRVS-FAGRPGGAPVWQAPKKKASQPP---PPPAPPLRSDSFA-ATKVF ORYLA4_32_PE17 NOISO HDGLPTEDPAGSRHS-TSSRISFGPVWNVPEKKKAASTSP-PPPPPPARSNSFA-AAKAH OTOGAGS_2886_PE1 NOISO SKSPRPGEGAEPKAS-SSGRSSFGPVWHVPDKKKA-PSSP-PPPPPPLRSDSFA-ATKSH PANTRX_11_PE1 NOISO GKGPRPEYNAEPKLA-APGRSNFGPVWYVPDKKKA-PSSP-PPPPPPLRSDSFA-ATKSH PIGX_6_PE3 NOISO SRSPRPENSAEPKLA-ASGRSTFGPVWYVPEKKKA-PSSP-PPPPPPLRRDSFA-ATKSH POEGU1_20_PE6 NOISO -KGPRTEEHSDGKLT-SSGRSSFGPVWYIPDKKKS--SSP-PPPPPPLRSDSFA-ATKGH PONPYX_10_PE2 NOISO GKGPRPEYNAEPKLA-APGRSNFGPVWYVPDKKKA-PSSP-PPPPPPLRSDSFA-ATKSH PTEVAGS_2083_PE1 NOISO SKSLRPEEGPGPRLA-TSGRSSFGPVWYVPDKKKA-AASP-PPPPPPLRSDSFA-ATKSH RATX_PE414 ENSRNOG00000024322 SKSPRPEDNIEPKIA-TSGRSNFGPVWYVPDKKKA-PS-P-PPLGLPLRSDSFAVAARGH RATX_PE415 ISOFORMIN SKSPRPEDNIEPKIA-TSGRSNFGPVWYVPDKKKA-PS-P-PPLGLPLRSDSFAVAARGH SPETRGS_3166_PE1 NOISO SKSPWPEDNAEPKA--TSGRSSFGPVWYVPDQKKN-SSSP-S-SPPLLRSDSFA-ATS-H TARSYGS_4663_PE1 NOISO GKSLRPEDSSEPKLA-PSGRSNFGPIWYVPDKKKA-PSSP-PPPLPPLRSDSFA-ATKSH TETNG3_PE72 ENSTNIG00000017158 ---GWEGERAASRAS-GAVKASVGPVWQVPEKNKEQPP---PPPPPPLRSDSFA-VTKVF TETNG3_PE73 ISOFORMIN ---GWEGERAASRAS-GAVKASVGPVWQVPEKNKEQPP---PPPPPPLRSDSFA-VTKVF TURTRGS_550_PE3 NOISO XXXXXXXXXX--XXX-XXXXXXXXXXXXXXXXXXX--------------XXXXX-XXXXX MATCH CONSENSUS ???????????????????R???GPVW?VP?KKK???????PPP??P?RSDSFA?AT???

AILMEGL194998_1_PE1 NOISO EKAQGPPFSE-A--GNVQHFPGLTHAQPPQPRSDW-RPDAADQQWRLVRPS-S---G-RR ANOCA81_2_PE4 NOISO ------------------------------------------------------------ BOVINX_88_PE9 NOISO EQTQGPTVSADA--APAQPLPGLSCVQP--HGGDWKRPEPADQLLRPARGA-D---G-RR CALJAX_9_PE1 ENSCJAG00000000928 EKGQGPVFSE-V--AAVQYFTALAQA---QPRSDW-RQEPTDRPWRSAHPGSL---G-KG CALJAX_9_PE2 ISOFORMIN EKGQGPVFSE-V--AAVQYFTALAQA---QPRSDW-RQEPTDRPWRSAHPGSL---G-KG CANFAX_7_PE3 NOISO EKAQGPPFSE-M--TNVQHFPGMTRA---QPRSDW-RPEPTDQQWRLVRPS-N---G-KR CAVPO126_2_PE3 NOISO EKPLGPPFSE-V--AATKLSAAPI---QLQPRGDW-RSDLADRQRRPRCLS-I---G-KE CHICK1_PE2106 NOISO EKAQGPAYSE-S--ASTQHFTALNRS---QARNDW-NSETVEQQRRPSRACDR-----KV DANRE11_47_PE9 NOISO EKSLVGLFPE-G--HTVYPLQR-----------------------PPCRAVDRQLEDVRH DANRE6_32_PE4 NOISO EKGLITDSCI-S--SDSHH----------------------------------------- ECHTEGS_4788_PE1 NOISO EKSPGSPYSE-V--ATAPPR--------GTPLTEW-RADPTDALQQLARPE-R-----RW FELCAGS_2696_PE1 NOISO EKAQGPPLSD-T--ASVQHFPGPPRA---QPRSDW-RPEPASQQWRPARPG-N---G-KR FUGRU13_1_PE137 ISOFORMIN ERGLVAQSEA-T--EFKP---PAESR-------------------RSS------------ FUGRU13_1_PE138 ISOFORMIN ERGLVAQSEA-T--EFKP---PAESR-------------------RSS------------ FUGRU13_1_PE139 ENSTRUG00000012349 ERGLVAQSEA-T--EFKP---PAESR-------------------RSS------------ FUGRU13_1_PE140 ISOFORMIN ERGLVAQSEA-T--EFKP---PAESR-------------------RSS------------ FUGRU57_1_PE17 NOISO PYSEGPIGPTKNKGRSTDKLAE---N---SDRNGF-----RSYQKTTP-------ES-RH GASACGROUPI_29_PE25 NOISO PYPEGPSGQAKTRSMAAEKLPE---S---S----L-----ASRKEKPS-------EA-RR GASACGROUPVIII_19_PE38 NOISO ERGLVATHPE-G--PEPHP---ENRR-------------------GHN------------ GORGOX_11_PE1 NOISO EKAQGPVFSE-A--AAAQHFTALAQA---QPRGDR-RPELTDRPWRSAHPGSL---G-KG HORSEX_7_PE4 ISOFORMIN EKAQGPPFSE-V--ADTQHFPGLTWA---QPRSDW-RPEPGDQQRRLAHPT-D---G-RR HORSEX_7_PE5 ENSECAG00000012150 EKAQGPPFSE-V--ADTQHFPGLTWA---QPRSDW-RPEPGDQQRRLAHPT-D---G-RR HSX_PE143 ENSG00000146950 EKAQGPVFSE-A--AAAQHFTALAQA---QPRGDR-RPELTDRPWRSAHPGSL---G-KG LOXAF94_6_PE2 NOISO EKSPGPLFSE-V--AATQDLTILSQG---LPPAEW-RTDPTEAPRQLVRAG-D---R-RW MACEUGS_5635_PE1 NOISO EKAQSPAYSE-T--ASTQHFTVLNRS---QPRSQW-RSEAADQQRRMIRVSGK------- MACMUX_8_PE9 ENSMMUG00000006193 EKAQGPVFSE-V--AVAQHFTAPAQA---QPRGDW-RPEPTDRPWRSAHPGSL---G-KG MICMUGS_799_PE3 NOISO EKAQGPLLSE-A--ATTKHFTALARA---QPHSDW-RPDPTDWPRRLVRPS-S---G-KG MONDO7_34_PE7 ENSMODG00000017449 EKSQSPAYAE-T--AGSQHFSVLGRA---PARSDW-RPDPPEQHRRAVRG----SEGKRS MONDO7_34_PE8 ISOFORMIN EKSQSPAYAE-T--AGSQHFSVLGRA---PARSDW-RPDPPEQHRRAVRG----SEGKRS MOUSEX_PE1950 ISOFORMIN EKARGPPFSD-L--ASMQHFITLPHV---QPRGDH-RMETTDRQWKLTHLS-S---G-KE MOUSEX_PE1951 ENSMUSG00000045180 EKARGPPFSD-L--ASMQHFITLPHV---QPRGDH-RMETTDRQWKLTHLS-S---G-KE MYOLUGS_3236_PE1 NOISO EKAQGPSFPE-A--ATAQHFPGLSRA---QSQGDW-RAEPADPQRKLARPVS------RR ORNANULTRA462_6_PE4 ENSOANG00000009689 EKTQGPTSSE-A--TSTQHFTVPTRA---QPGNEW-LSETADQQRRPVRVSDRSAEGKRI ORNANULTRA462_6_PE5 ISOFORMIN EKTQGPTSSE-A--TSTQHFTVPTRA---QPGNEW-LSETADQQRRPVRVSDRSAEGKRI ORYLA2_17_PE12 NOISO PYSDGPSGAPQS-GRSLGKPP--------------------------------------- ORYLA4_32_PE17 NOISO ERGLVTAPPE-G--LESHCRALKNLR-------------------SHS------------ OTOGAGS_2886_PE1 NOISO GQVPSPMLSE-A--ATTQHFTVLAQT---QPRSDW-RPDTADRLRRPVRXXXX---X-XX PANTRX_11_PE1 NOISO EKAQGPVFSE-A--AAAQHFTALAQA---QPRGDR-RPELTDRPWRSAHPGSL---G-KG PIGX_6_PE3 NOISO EKTQG-PFAE-A--ATSQHFPGLVGA---QAHGDW-RPEVAEHLQRPGPAN-D---A-RR POEGU1_20_PE6 NOISO EKAHGPVFSE-G--ASTQHFTALNRS---QPRSDW-SLETAE-QRRPSRACDR-----RI PONPYX_10_PE2 NOISO EKAQGPVFSE-A--AAAQHFTALAQV---QPRSDW-RPELADRPWRSAHPGSL---G-KG PTEVAGS_2083_PE1 NOISO EKAQGPPFSE-A--AGAAHFARLRRA---QSRGEC-RPEPADQRRRPARLGNG------- RATX_PE414 ENSRNOG00000024322 EKARGPPFSD-L--ASMQHFTTLPHV---QPRGDR-RMETTDRQWKLAHPS-S---G-KE RATX_PE415 ISOFORMIN EKARGPPFSD-L--ASMQHFTTLPHV---QPRGDR-RMETTDRQWKLAHPS-S---G-KE SPETRGS_3166_PE1 NOISO ERCKALQFSK-A--T--PDFTGLXXX---XXXXXX-XXXXXXXXXXXXXXXXX---X-XX TARSYGS_4663_PE1 NOISO EKAQGPPFSE-A--ATVQHFTALART---QPRGEW-RPEPTDRLWRPARLG-G---G-KG TETNG3_PE72 ENSTNIG00000017158 PYSEGP---TKSKGRSSEKLLE---N---GERGGF-----RSYQKNTP-------ES-RN TETNG3_PE73 ISOFORMIN PYSEGP---TKSKGRSSEKLLE---N---GERGGF-----RSYQKNTP-------ES-RN TURTRGS_550_PE3 NOISO XXXXXXXXXX-X--XXXXXXXXXXXX---X-XXXX-XXXXXX-XXXXXXXXXX-----XX MATCH CONSENSUS E???????????????????????????????????????????????????????????

AILMEGL194998_1_PE1 NOISO AGSTGCAPDVPLDGGVLPSDPRAGGLPGAPGRLQASLSSTDVRFPQPSSGC--QHSRQYS ANOCA81_2_PE4 NOISO ------------------------------------------------------------ BOVINX_88_PE9 NOISO AASSGCAPGAHVDCGWPACDSGSRALLGAPSRLQASLSSTDVRRPQPSPVC--QHPRHLS CALJAX_9_PE1 ENSCJAG00000000928 SGGPGCLREVRADGSWPPSKDTL---QGASGRLQASLSSSDVRFPQSPRSG--RHPPPYS CALJAX_9_PE2 ISOFORMIN SGGPGCLREVRADGSWPPSKDTL---QGASGRLQASLSSSDVRFPQSPRSG--RHPPPYS CANFAX_7_PE3 NOISO AGSSGCAPDAPLDCGVLPSDHRTGGFPGVPGRLQASLSSTDVRFPQ-SYGC--QHPRQYS CAVPO126_2_PE3 NOISO SGGHHE----------------CSQPGGPLGRVQASLSSADAPQTQPPHRG--QHLCQCS CHICK1_PE2106 NOISO GG-SNYKSDLSSEHAFSAVGERYNSHAGTVSKLQSSLSSTDVRFAQPAYNY--HHQHQYS DANRE11_47_PE9 NOISO SYNSPPKKD-YLE-PYLPVE---DYPNQLNPTKLFSLSSTDVRQGQNPFASEFQHQRQHS DANRE6_32_PE4 NOISO ----QYIQR-------------------TSSDKTYSLSTTDIRDSHPSYGHAPYHAQQYS ECHTEGS_4788_PE1 NOISO SGNCGHPVDLPLEGRWXXXXXXXXXXXXXXXXXXXXXXXXXX------XXX--XXXXXXX FELCAGS_2696_PE1 NOISO VGSSGPVPHVPLDGGVPTP------DHGAPGRLQASLSSTDVRFPQASCGC--QHPRQYS FUGRU13_1_PE137 ISOFORMIN ----NLSP-NIGRDGFHASDK--SILKQFSSHKQFSLSSSDVRQ----G--QPCHQRHHS FUGRU13_1_PE138 ISOFORMIN ----NLSP-NIGRDGFHASDK--SILKQFSSHKQFSLSSSDVRQ----G--QPCHQRHHS FUGRU13_1_PE139 ENSTRUG00000012349 ----NLSP-NIGRDGFHASDK--SILKQFSSHKQFSLSSSDVRQ----G--QPCHQRHHS FUGRU13_1_PE140 ISOFORMIN ----NLSP-NIGRDGFHASDK--SILKQFSSHKQFSLSSSDVRQ----G--QPCHQRHHS FUGRU57_1_PE17 NOISO SLTPLSAND--FLHPSF-AADH--NQKQLHTNKLFSLSSNDVRHSHHST--LPAHQRQYS GASACGROUPI_29_PE25 NOISO SLNRLPTKD--FLHPNA-AD---HNQTRLPPSRLFSLSSNDVRQPHHSQ--LAAHQRQHS GASACGROUPVIII_19_PE38 NOISO ----PPQK-NEPEAPR-------RAVRQVQPLGSANSSRCPVTATSGKA--RPPTRD-ST GORGOX_11_PE1 NOISO SGGPGCPQEAHADGSWPPSKD------GASSRLQASLSSSDVRFLQSPHSG--RHPPLYS HORSEX_7_PE4 ISOFORMIN PGGSVWAPDAPCEWPA--S------DHEAPSMLQASLSSTDVRCPQPSYGY--QHLRQYS HORSEX_7_PE5 ENSECAG00000012150 PGGSVWAPDAPCEWPA--S------DHEAPSMLQASLSSTDVRCPQPSYGY--QHLRQYS HSX_PE143 ENSG00000146950 SGGPGCPQEAHADGSWPPSKD------GASSRLQASLSSSDVRFPQSPHSG--RHPPLYS LOXAF94_6_PE2 NOISO PGNCGHHVDLPLDGGWPPSDGRVGGFPGTPSRLQASLSSCDVRFAQSPYGH--QHPRQYS MACEUGS_5635_PE1 NOISO -G-PICHLDLNLDYSWPSSDDRY------PSRLQSSLSSTDVRFAQSAYGY--HHQRQYS MACMUX_8_PE9 ENSMMUG00000006193 SGGPGCPQEARADGSWPPSKD------GASSRLQASLSSSDVRLPQSPRSG--RHPPLYS MICMUGS_799_PE3 NOISO AGGPGYLQEARLDYGWPSEDK-------APGRLQASLSSTDVRFPQPPRGG--QHPRHYS MONDO7_34_PE7 ENSMODG00000017449 TN-APYRADLSFDYGWPSSDGRSSH---STNRLQSSLSSTDVRFAQSAPGY--HHQRQYS MONDO7_34_PE8 ISOFORMIN TN-APYRADLSFDYGWPSSDGRSSH---STNRLQSSLSSTDVRFAQSAPGY--HHQRQYS MOUSEX_PE1950 ISOFORMIN IGNVGYQSEGHLDCRWLCSDDRAGRPSGPPGRLQFS----DVHFLKSYHGS--QHQQQCS MOUSEX_PE1951 ENSMUSG00000045180 IGNVGYQSEGHLDCRWLCSDDRAGRPSGPPGRLQFS----DVHFLKSYHGS--QHQQQCS MYOLUGS_3236_PE1 NOISO PESSGCAAAAPLDCGWPSNP-------GAPSRLHASLSSTDVRFPPSAHAC--QHQRQCS ORNANULTRA462_6_PE4 ENSOANG00000009689 AH-SIYLSDLSLDRTFLSSDDPCNSNPGTNPSLQASLSSTDVRFAQPAYGF--HHQRQFS ORNANULTRA462_6_PE5 ISOFORMIN AH-SIYLSDLSLDRTFLSSDDPCNSNPGTNPSLQASLSSTDVRFAQPAYGF--HHQRQFS ORYLA2_17_PE12 NOISO ------------------------ESSQRRPSKLFSLSSSDVRQSHYAV--PPAHQRQHS ORYLA4_32_PE17 NOISO ----ISLK-NDSRNILTSTDK--STHAAFSPNKPSSLSGSDAHHGHGAS--QPFQQPHHS OTOGAGS_2886_PE1 NOISO XXXXXXXXXXXXXXXXXXXXXXX---XXXXXXXXXXXXXXXXXXX---XXX--XXXXXXX PANTRX_11_PE1 NOISO SGGPGCPQEAHADSSWPPSKD------GASSRLQASLSSSDVRFLQSPHSG--RHPPLYS PIGX_6_PE3 NOISO AGGSGWVPGAYLDYGWPPC------DSGAPSRLQASLSSTDVRCPQASYRC--QHPRHSS POEGU1_20_PE6 NOISO SS-SNYKSDLSSEHTFSSAGERYSSNAGTVSKLQ----PTDVRFAQSAYSH--HHQHQYS PONPYX_10_PE2 NOISO SGGPGCPREARADGSWPPSKD------GASSRLQASLSSSDVRFLQSPHSG--RHPPLYS PTEVAGS_2083_PE1 NOISO RPGSVGSPQASPDCGWPPSGP------GVPSRLQASVSSTDVRLPPSPSGW--QHLRHCS RATX_PE414 ENSRNOG00000024322 IGNVGYQPEGHLDCRWLCSDDRAGRPSGAPGRHQFSLSSTDVHFLKSYHGS--QHPQPCS RATX_PE415 ISOFORMIN IGNVGYQPEGHLDCRWLCSDDRAGRPSGAPGRHQFSLSSTDVHFLKSYHGS--QHPQPCS SPETRGS_3166_PE1 NOISO XGGHGYPLEGHTDCGWLCLDDRA---GS-SLGAPDRLFGSEVHFRQPHPGG--QHLRQCS TARSYGS_4663_PE1 NOISO AGGPGCPQEARPECGWPSSDN------RAPGRLQASLSSTDVRVPQSSHGG--QHPRQYS TETNG3_PE72 ENSTNIG00000017158 SLAPLSAKD--LLHPSS-AAGQNQNQNQLQSNKPFSLSSTDVRQSQHSA--PPAHQRQYS TETNG3_PE73 ISOFORMIN SLAPLSAKD--LLHPSS-AAGQNQNQNQLQSNKPFSLSSTDVRQSQHSA--PPAHQRQYS TURTRGS_550_PE3 NOISO -X-XXXXXXXXXXXXXXXXXXXXXX---XXXXXXXXX-XXXXXXXXXXXXX--XXXXXXX MATCH CONSENSUS ???????????????????????????????????SLS??DV????????????H????S

AILMEGL194998_1_PE1 NOISO DESPFSHEGPGATTSLREQPRVAVPGGRQEP----SVDR-GPT--T-AP----------- ANOCA81_2_PE4 NOISO ------------------------------------------------------------ BOVINX_88_PE9 NOISO DEGPFFRKGPRATTWLGEPLPADC-----------LGDN-TPAAIVIGG----------- CALJAX_9_PE1 ENSCJAG00000000928 DQSTLCADSLGQEPA-----------------AASSQND-SPP--QVRG----------- CALJAX_9_PE2 ISOFORMIN DQSTLCADSLGQEPA-----------------AASSQND-SPP--QVRG----------- CANFAX_7_PE3 NOISO DESPFCHEGPSQEPSANPF-----------------QDD-SPT--QVRW----------- CAVPO126_2_PE3 NOISO DEGVT-----GKPMSLREWHRVAPSGGWQDLPVPQCQDI-GPP--QVRW----------- CHICK1_PE2106 NOISO DESTFFH-NTRMLAAPKDQQPFLSYGGIQELPADHFHG-YNLN--HTRLFNTCSS----S DANRE11_47_PE9 NOISO DDSPFSVY-NNSTCSSKSQSVGSYYRSLQDLPNNVSNQNKTR-----------------T DANRE6_32_PE4 NOISO DEGTFHA-QTRTAMKPPFSGY---FSSMQELHTNNHMQLNSQN--QTGRPAASLSVSEMS ECHTEGS_4788_PE1 NOISO XXXXXXXX------XXXXXXXXXX--XX--------XXX-XXX--XXXX----------- FELCAGS_2696_PE1 NOISO DESPFCHDGPRRPPGAAHR----------------VQDD-GPT--RLRW----------- FUGRU13_1_PE137 ISOFORMIN DK-------------------GAYYCSTQELPVNGSAQTQRKF--SN--AS---S----S FUGRU13_1_PE138 ISOFORMIN DKGTLFS-QPWAPPFPKPQTVGAYYCSTQELPVNGSAQTQRKF--SN--AS---S----S FUGRU13_1_PE139 ENSTRUG00000012349 DKGTLFS-QPWAPPFPKPQTVGAYYCSTQELPVNGSAQTQRKF--SN--AS---S----S FUGRU13_1_PE140 ISOFORMIN DKGTLFS-QPWAPPFPKPQTVGAYYCSTQELPVNGSAQTQRKF--SN--AS---S----S FUGRU57_1_PE17 NOISO DESPRYL-QTRTSTPTKIQSVGSYYRSLQDLPKNAFGHKQSAE----------------- GASACGROUPI_29_PE25 NOISO DESPFCK-QTRPAPATKVQSVGSYYRSLQDLPANIFSRKHVRH-----------STAFVA GASACGROUPVIII_19_PE38 NOISO GTRAYFTFQARAVSVPK-------------IAERGGVPQQHAN--HRRNLSTSLS----T GORGOX_11_PE1 NOISO DHSPLCADSLGQEPG-----------------AASFQND-SPP--QVRG----------- HORSEX_7_PE4 ISOFORMIN DESPFFATT-----SPRKQLHVALTGGF--------QDD-SPT--QVRW----------- HORSEX_7_PE5 ENSECAG00000012150 DESPFFATT-----SPRKQLHVALTGGF--------QDD-SPT--QVRW----------- HSX_PE143 ENSG00000146950 DHSPLCADSLGQEPG-----------------AASFQND-SPP--QVRG----------- LOXAF94_6_PE2 NOISO DESPILHEGPRPPASPRELWQLALLRGRQESPADHFQDN-GFA--PVRW----------- MACEUGS_5635_PE1 NOISO DESTFFH-SSRAASLWWP------------PRAACFQT-CNPA--QVRLLSG-------- MACMUX_8_PE9 ENSMMUG00000006193 DHSPLCADSLGQEPA-----------------AASSQND-SLP--QVRG----------- MICMUGS_799_PE3 NOISO DESPPCVTRLGPEPP-----------------AAHFQGD-GPP--QLRW----------- MONDO7_34_PE7 ENSMODG00000017449 DESTFFQ-GSRASGSSKE---PRHYGGPPELPADPPQT-YSPA--QGRLLNAPPS----A MONDO7_34_PE8 ISOFORMIN DESTFFQ-GSRASGSSKE---PRHYGGPPELPADPPQT-YSPA--QGRLLNAPPS----A MOUSEX_PE1950 ISOFORMIN DESP------RAPSSPRELLHITPGGGLQ-EPPEPSQDD-NPT--QVRW----------- MOUSEX_PE1951 ENSMUSG00000045180 DESP------RAPSSPRELLHITPGGGLQ-EPPEPSQDD-NPT--QVRW----------- MYOLUGS_3236_PE1 NOISO DESPFLHEGLRQGAGG----------------PASFQDA-SPT--PARQ----------- ORNANULTRA462_6_PE4 ENSOANG00000009689 DESTFFH-HPR----------PAHCGGQPEPSTERFCG-RSPT--QIRRVGAALP----A ORNANULTRA462_6_PE5 ISOFORMIN DESTFFH-HPRVSAAPKELRKPAHCGGQPEPSTERFCG-RSPT--QIRRVGAALP----A ORYLA2_17_PE12 NOISO DESPFYL-QARAAPPTRIQSVGSYYRSLQDLPANAFSRRQGRH-----------SAATTN ORYLA4_32_PE17 NOISO DKSAYFP-QPWTPPASKTQSVGGYHSSLQDLPTHSSAQHLSQN--QRWSLS---S----N OTOGAGS_2886_PE1 NOISO XXXXXXXXXXXXXXX-----------------XXTSWDD-RHT--Q-VK----------- PANTRX_11_PE1 NOISO DHSPLCADSLGQEPG-----------------AASFQND-SPP--QVRG----------- PIGX_6_PE3 NOISO DESPFCREGPRATTWLREQ-----------PPAEGFQDD-SPT--QVGW----------- POEGU1_20_PE6 NOISO DESTFYH-T-----APKDQQHYLSYSGIQDPNQASLL--------------YTSS----L PONPYX_10_PE2 NOISO DHSPLCADSLGQEPG-----------------AASFQND-SPP--QVRG----------- PTEVAGS_2083_PE1 NOISO DESLFFPDSPPGSPCH----------------P----G---------------------- RATX_PE414 ENSRNOG00000024322 DESP------RFPSSPRELLRITPSGCLQ-EPPELSQDD-NPA--QVRW----------- RATX_PE415 ISOFORMIN DESP------RFPSSPRELLRITPSGCLQ-EPPELSQDD-NPA--QVRW----------- SPETRGS_3166_PE1 NOISO DQSPLCAGGPRQEPL-----------------ATHHQDD-GPS--VGRW----------- TARSYGS_4663_PE1 NOISO DDSPFCPENLRQESP-----------------ATCLQDD-SPP--QVKW----------- TETNG3_PE72 ENSTNIG00000017158 DESPRYL-QARTAAPSRMQSVGSYYRSLQDLPRNALGHKQVRH-----------STASVA TETNG3_PE73 ISOFORMIN DESPRYL-QARTAAPRMPSA---------------------------------------- TURTRGS_550_PE3 NOISO XXXXXXX-XXX---XXXX---XXXXX----XXXXXXXX-XXXX--XXXXXXXXXX----X MATCH CONSENSUS D???????????????????????????????????????????????????????????

AILMEGL194998_1_PE1 NOISO LGATSQK---GDSCGQSRYYCVTNRQ-------APPLHEE--SWPPDMAR----G----A ANOCA81_2_PE4 NOISO ------------------------------------------------------------ BOVINX_88_PE9 NOISO PRAADQR---GDCSAQSRYYCVMSRPGPQWGAPA-------------------------- CALJAX_9_PE1 ENSCJAG00000000928 LSSWDQK---LGSGWKGPWPP-RVQ----GGPQAAQLRAG--CWPSDVAP----R----A CALJAX_9_PE2 ISOFORMIN LSSWDQK---LGSGWKGPWPP-RVQ----GGPQAAQLRAG--CWPSDVAP----R----A CANFAX_7_PE3 NOISO PSATNQK---GDSGGQSRYYCVTTRQCLQGSTQAAQLHED--HWHPDVAP----G----A CAVPO126_2_PE3 NOISO PKAADQ-----------SYSCVAAR--------QPPFPGE--CWHWNVAP----G----T CHICK1_PE2106 NOISO NSAAEQK---ADNTGQSRYYCVTAKQPAQGSSKPLQLKDD--NWKPAAGA----DVSLGP DANRE11_47_PE9 NOISO STVFDPN---HDGQAHFRYYCITAQQPYLESSSHCRMVDE--QSSEMGKAQGATDRSFVG DANRE6_32_PE4 NOISO HNGRDRMSIGSQGGNKERYFPPQSQHHDN------KERSA--SFKQNENQ----HYVSAP ECHTEGS_4788_PE1 NOISO XXXXXXX---XX--XXXXXXXXXXXX-------XXXXXXX--XXXXXXXX----X----X FELCAGS_2696_PE1 NOISO PGATEQK---GDSGGQSRYYCVQAS------AQAGQPHEE--YWQSDRAA----E----A FUGRU13_1_PE137 ISOFORMIN NATADQN---ADISGQSQYYCVTTCQLAQPNPPGKSEDL----AKPGN-----------A FUGRU13_1_PE138 ISOFORMIN NATADQN---ADISGQSQYYCVTTCQLAQPNPPGKSEDL----AKPGN-----------A FUGRU13_1_PE139 ENSTRUG00000012349 NATADQN---ADISGQSQYYCVTTCQLAQPNPPGKSEDL----AKPGN-----------A FUGRU13_1_PE140 ISOFORMIN NATADQN---ADISGQSQYYCVTTCQLAQPNPPGKSEDL----AKPGN-----------A FUGRU57_1_PE17 NOISO --------------------------------LQARP----------------------- GASACGROUPI_29_PE25 NOISO SSAANQE---N--GRHNRYHGLASKHSVQTAELQVRRGEAEG-RRGEMEEPPRVDPNE-- GASACGROUPVIII_19_PE38 NOISO AAAAEHN---AESGPHSRYYCVTTVQAALREPPPARTEDR--NGVTGSDL----APAVGE GORGOX_11_PE1 NOISO LSSCDQN---LGSGWQGPRP--CVQ----GDLQAAQLWAG--CWPSDTAL----G----A HORSEX_7_PE4 ISOFORMIN PSAADQK---GDSSGQSR-FCAPMRQCLQGGTRAAR-RGA--GWHPATQP----G----P HORSEX_7_PE5 ENSECAG00000012150 PSAADQK---GDSSGQSR-FCAPMRQCLQGGTRAAR-RGA--GWHPATQP----G----P HSX_PE143 ENSG00000146950 LSSCDQK---LGSGWQGPRP--CVQ----GDLQAAQLWAG--CWPSDTAL----G----A LOXAF94_6_PE2 NOISO LGAADQK---VEGGGQSRYYCASSKQPVQGSAQTPQLSKE--CWLSVAGA----GVAQGV MACEUGS_5635_PE1 NOISO ---CDQR---MENTGQSRYYCIQ------GSSQPQLLKDE--YWRSGIGT----DVSFGP MACMUX_8_PE9 ENSMMUG00000006193 LSSCDQK---LGSGWQGPRP--CVQ----GGPQVAQLWAG--CWPSDTAP----G----A MICMUGS_799_PE3 NOISO LGAADQT---AGGSGQGPRH--CVQAALQAGTKAAQPRGG--RWPCDAAP----G----A MONDO7_34_PE7 ENSMODG00000017449 NSGADPK---MEGSAQP---------------------HD--HWKSGAGP----DGASGP MONDO7_34_PE8 ISOFORMIN NSGADPK---MEGSAQPRYYCVTKKQPAQGSNQPQLLKDD--HWKSGAGP----DGASGP MOUSEX_PE1950 ISOFORMIN PGSAHQK---LDDRGRSHYFPGSLRQPVQGSAQVVIPRGD--YWHSDTTP----V----D MOUSEX_PE1951 ENSMUSG00000045180 PGSAHQK---LDDRGRSHYFPGSLRQPVQGSAQVVIPRGD--YWHSDTTP----V----D MYOLUGS_3236_PE1 NOISO PSAADRK---GDSAGQSHH------HSVQGGAQAAQPRDS--CWRCSSPL----G----A ORNANULTRA462_6_PE4 ENSOANG00000009689 DCATDQM---LEITGQT------TKQPTQGSSQPLQLKDE--CWKPSSGA----DMLLAP ORNANULTRA462_6_PE5 ISOFORMIN DCATDQM---LEITGQSRFYSVATKQPTQGSSQPLQLKDE--CWKPSSGA----DMLLAP ORYLA2_17_PE12 NOISO PS--------QESGGVSRYYGTAAK---QAAELKARQGCSSAPWMNSSNS---------- ORYLA4_32_PE17 NOISO LSSAATD---HESGGPSRYYCITTSHGTHPNHPSLSGIP----EVRGS-A----AGLPQE OTOGAGS_2886_PE1 NOISO VPCCDQK---V-YHWQGSRSYMFHQAALQAGAWAAQPRGG--CWPPSVAP----G----A PANTRX_11_PE1 NOISO LSSCDQK---LGSGWQGPRP--CVQ----GDPQAAQLWAG--CWPSDTAL----G----A PIGX_6_PE3 NOISO PSAADRK---GDGGAQSRYYCVTSRRCLQGGAPDAQPRSY--P----------------- POEGU1_20_PE6 NOISO NSSAEQK---VDNTGQSRYYCVTAKQPAQGSSKPLQLKND--SWEPAVGT----DFHYPV PONPYX_10_PE2 NOISO LSSCDQK---LGSGWQGPRP--CVQ----GGPQAAQFWAG--CWPSDTAP----G----A PTEVAGS_2083_PE1 NOISO ----------SGCERPSPWAP--------GAPPAA---SR--TRPSDVQP---------- RATX_PE414 ENSRNOG00000024322 PGSVNQK---LDDRGRSHYFSVPHRQPVHGSAHVLIPRSD--YWHSDTTP----V----D RATX_PE415 ISOFORMIN PGSVNQK---LDDRGRSHYFSVPHRQPVHGSAHVLIPRSD--YWHSDTTP----V----D SPETRGS_3166_PE1 NOISO PGAANQK---VDSGGLS-HYY-CVQ----GSTQVTKLRGE--SWPSDAAS----G----A TARSYGS_4663_PE1 NOISO LGAMEQK---VETGGPS-HHH-CVQ----GGPQAAQLRGG--CWPSDVAP----G----A TETNG3_PE72 ENSTNIG00000017158 GCAANPN---AESEGHRRHYGLASKPSAQGAELQARQGRAEG-WSGTTDRPHRPGGRD-- TETNG3_PE73 ISOFORMIN --------------------TNRSKPSAQGAELQARQGRAEG-WSGTTDRPHRPGGRD-- TURTRGS_550_PE3 NOISO XX-XXXX---XXXXXXXXXXXXXX-----X-----XX-XX--XXXXXXXX----XXXXXX MATCH CONSENSUS ????????????????????????????????????????????????????????????

AILMEGL194998_1_PE1 NOISO QEYPPSHPMG-QKARCSLLQNEAAP--DPHER------------------DRGDPADRAA ANOCA81_2_PE4 NOISO ------------------------------------------------------------ BOVINX_88_PE9 NOISO -----------PQPRCYPSRLEGAP--GARQR------------------SRADPVDRAP CALJAX_9_PE1 ENSCJAG00000000928 LEHLPQPLVG-QSPRHHLPQPEDPP--DACEI------------------GQCYPLDAGA CALJAX_9_PE2 ISOFORMIN LEHLPQPLVG-QSPRHHLPQPEDPP--DACEI------------------GQCYPLDAGA CANFAX_7_PE3 NOISO PEHPTAHPMG-QKARCYLPQHEEAL--DAHER------------------DRGDPVDRAA CAVPO126_2_PE3 NOISO SEYLSLHPVMNPNPRCPLARQEE----------------------------PGPLPDTVT CHICK1_PE2106 NOISO YENPAVV-TMAQKPKCYLPQQSVESCLEGCEN------------------SSHYTVDRES DANRE11_47_PE9 NOISO SQ-KVIK-AKHPQLYLSLPENKRSNGYNKQSISPASAQAVS--PISNNLISKHSSVERET DANRE6_32_PE4 NOISO SNPL--N-M---------SDSTKHNELRGCQK------------------QHHVHGSDEL ECHTEGS_4788_PE1 NOISO XXXXXXPPPAGPKQLCSLPQHGNSE--------------------------REPDPPRGV FELCAGS_2696_PE1 NOISO HELPTEHPMGHGP-WGHIQHEEEAP--DARE------------------------SDQAA FUGRU13_1_PE137 ISOFORMIN -QKSLSP-PSVTKAKYNLPQHIKQND-----------------------------VKATA FUGRU13_1_PE138 ISOFORMIN -QKSLSP-PSVTKAKYNLPQHIKQNDGKHQAA----------------STAESCVVKATA FUGRU13_1_PE139 ENSTRUG00000012349 -QKSLSP-PSVTKAKYNLPQHIKQNDGKHQAA----------------STAESCVVKATA FUGRU13_1_PE140 ISOFORMIN -QKSLSP-PSVTKAKYNLPQHIKQND-----------------------------VKATA FUGRU57_1_PE17 NOISO -----GKAETNVKSKYSLPQFQMPYSVNKEHNGHSPLGTGLHYDHKSSELSVPSPEDSTK GASACGROUPI_29_PE25 NOISO ------------------------------------------------------------ GASACGROUPVIII_19_PE38 NOISO -RNSLSL-QTVPKVTYHLPQQMEGPGPRS-----------------------------GS GORGOX_11_PE1 NOISO LESLPPPTVG-QSPRHHLPQPEGPP--DARET------------------GRCYPLDTGA HORSEX_7_PE4 ISOFORMIN KPG----------AACLCLRG------------------------------PGAPCEASK HORSEX_7_PE5 ENSECAG00000012150 KPG----------AACLCLRG------------------------------PGAPCEASK HSX_PE143 ENSG00000146950 LESLPPPTVG-QSPRHHLPQPEGPP--DARET------------------GRCYPLDKGA LOXAF94_6_PE2 NOISO QECPSTHRMS-PKPRCYLPQHGKML--DPNER------------------EQWHPLDRGG MACEUGS_5635_PE1 NOISO HENLAIN-MMGQKTKCHLPHCE--SLLDFSER------------------NNSYPMDRGG MACMUX_8_PE9 ENSMMUG00000006193 LKSLPPPTVG-QSPHRHLPQPEGPP--DACET------------------GRCYPLDTGA MICMUGS_799_PE3 NOISO LQHPPSQPVG-QGPRRHLPQHEGLP--GARET------------------GWCHPPDAGA MONDO7_34_PE7 ENSMODG00000017449 PENLALH-TTAPKPKSHLPHCE-EPSVDFSDR------------------NSSHPMERGG MONDO7_34_PE8 ISOFORMIN PENLALH-TTAPKPKSHLPHCE-EPSVDFSDR------------------NSSHPMERGG MOUSEX_PE1950 ISOFORMIN LEYPLLRP---VGQRTYLQQHEETP--ASHEK------------------EGYHQLNAGI MOUSEX_PE1951 ENSMUSG00000045180 LEYPLLRP---VGQRTYLQQHEETP--ASHEK------------------EGYHQLNAGI MYOLUGS_3236_PE1 NOISO HACPATHPAG-QKPRCHPPQHQESL--DAHKE------------------RGDP------ ORNANULTRA462_6_PE4 ENSOANG00000009689 YENPTAP-ATGQRTKYSLPQNC--ELVDICER------------------SSSCRADGGE ORNANULTRA462_6_PE5 ISOFORMIN YENPTAP-ATGQRTKYSLPQNC--ELVDICER------------------SSSCRADGGE ORYLA2_17_PE12 NOISO --VLPA--SLKTKAKFSAP--PTAYGEKKDHS------GGLTYEFS-----ARDTNDPLK ORYLA4_32_PE17 NOISO -RRSTSP-QAAPKARHHLPQHSPRSEDNAAH----------------------------- OTOGAGS_2886_PE1 NOISO LQYSPLHLGG-HSSRRHLSQHPELL--DTHEA------------------GRCYALDTGA PANTRX_11_PE1 NOISO LESLPPPTVG-QSPRHHLPQPEGPP--DARET------------------GRCYPLDTGA PIGX_6_PE3 NOISO ------------------SGFEGAP--GARQR------------------GRAMPADR-- POEGU1_20_PE6 NOISO DREEDAR-CAAVEESKKPNHTEKSGQKQTCEN------------------SSEASETRHG PONPYX_10_PE2 NOISO LESLPPPTVG-QSPRHHLPQPEGPP--DACET------------------GQCYPLDAGA PTEVAGS_2083_PE1 NOISO ---SAPPQVG-H---ARLPLCEVLP----GST------------------GQRISGDRGA RATX_PE414 ENSRNOG00000024322 LECPLLRP---D-QRGYPQQYEETP--ASHER------------------GGYQQLNAGI RATX_PE415 ISOFORMIN LECPLLRP---D-QRGYPQQYEETP--ASHER------------------GGYQQLNAGI SPETRGS_3166_PE1 NOISO LEHAPTHLMG-QSPRCYLPQHEQAL--DAPER------------------EQCPLLDSGA TARSYGS_4663_PE1 NOISO LECPPLHLAG-QSPHHHLPQHEGAL--DAHET------------------GRCYSLNAGT TETNG3_PE72 ENSTNIG00000017158 -AAYYGSFRTNGKTRYSLPQFQVPYSVKKEPSGPPHLGGGP------------------- TETNG3_PE73 ISOFORMIN -AAYYGSFRTNGKTRYSLPQFQVPYSVKKEPSGPPHLGGGP------------------- TURTRGS_550_PE3 NOISO XXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXX------------------XXXXPADREA MATCH CONSENSUS ????????????????????????????????????????????????????????????

AILMEGL194998_1_PE1 NOISO EG---RSAGSEEPPRASR----------VDRAGG-KNTSDGFTWADGENSKISRQKTPML ANOCA81_2_PE4 NOISO ------------------------------------------------------------ BOVINX_88_PE9 NOISO ED----------PPGAGL----------LDRGGR-KRV---VGSLDDGGGEICPLQTPML CALJAX_9_PE1 ENSCJAG00000000928 EG---CSLRAQEPPRFSH----------GEKASQ--RPAAGFLWADRDSSRICLQETPLL CALJAX_9_PE2 ISOFORMIN EG---CSLRAQEPPRFSH----------GEKASQ--RPAAGFLWADRDSSRICLQETPLL CANFAX_7_PE3 NOISO EG---RSTGSEEPQRASH----------SEKACL-K-KTADFMWADGESSKISRQKTPML CAVPO126_2_PE3 NOISO GG---GALGFHKLSRTSH----------AE---Q-GPLAGGFRVADGEGSRISRQRTPML CHICK1_PE2106 NOISO DV---RFAVVEEAKKTNH----------AEKSGQ-KPAQKDFRWGKDESSKISPQRTPML DANRE11_47_PE9 NOISO QK------KKDKPQPSRHI-----PNHQTEQNSM-YTYQHDNPWISKQDLKICPHKTPLL DANRE6_32_PE4 NOISO SG---SYPPSKQPEHRRS----------AGHL-H-HKEYSQQPFPTKSESKICPQKTPML ECHTEGS_4788_PE1 NOISO EG---LPLGADESPQTSH----------VEKASPMRAADSDSQWGHGESSKISPQNTPML FELCAGS_2696_PE1 NOISO KG---HPVGSEEPQTAAH----------GTGAAG-KEAADGFLWAAGESGKISPQKTPML FUGRU13_1_PE137 ISOFORMIN DDRGGQRGLNAQTQSSSAPASRPVEQRRSLPPQH-RESFQETRNHSQASNQISPQSTPLL FUGRU13_1_PE138 ISOFORMIN DDRGGQRGLNAQTQSSSAPASRPVEQRRSLPPQH-RESFQETRNHSQASNQISPQSTPLL FUGRU13_1_PE139 ENSTRUG00000012349 DDRGGQRGLNAQTQSSSAPASRPVEQRRSLPPQH-RESFQETRNHSQASNQISPQSTPLL FUGRU13_1_PE140 ISOFORMIN DDRGGQRGLNAQTQSSSAPASRPVEQRRSLPPQH-RESFQETRNHSQASNQISPQSTPLL FUGRU57_1_PE17 NOISO KCEG-RPNDVKKHFPAYQ-----SINH---SV---SLSRHQDPWLPQEDHRISPLKTPLL GASACGROUPI_29_PE25 NOISO --------------PSSS-----N--------------TNARPVGAAGRPPNLSPENPLL GASACGROUPVIII_19_PE38 NOISO DGRGSPRGAGAEAQFPSHASGWQHEQRRPPPQ-----HHQDVQHHGQAGNKICAQATPML GORGOX_11_PE1 NOISO KG---CSMGAQEPPRASR----------AEKASQ--RLAASITWADGESSRICPQETPLL HORSEX_7_PE4 ISOFORMIN AG---T------LSARSQ----------ETRAGL-KKTMTSLPWADGESSKISPRQTPML HORSEX_7_PE5 ENSECAG00000012150 AG---T------LSARSQ----------ETRAGL-KKTMTSLPWADGESSKISPRQTPML HSX_PE143 ENSG00000146950 EG---CSAGAQEPPRASR----------AEKASQ--RLAASITWADGESSRICPQETPLL LOXAF94_6_PE2 NOISO EG---WPMGTEEPPRTSH----------VEKASPKRTADGNFQWVDGESSKISPQKTPML MACEUGS_5635_PE1 NOISO DG---WSTGEDEPQKFSH----------LEKANQ-KRVAEDFKWGEEESSKISPQKTPML MACMUX_8_PE9 ENSMMUG00000006193 EG---CSAGAQEPPRASR----------VEK--------ASITWADGESSRICPQETPLL MICMUGS_799_PE3 NOISO KG---CSTTAQEPPGASH----------ADQAGQ-HTAAGGFKWEYGQSSRISPQKTPLL MONDO7_34_PE7 ENSMODG00000017449 DG---WSAGEEEPQKSSH----------VEKTNQ-KRVTEDFKWGEEESSKISPLKTPML MONDO7_34_PE8 ISOFORMIN DG---WSAGEEEPQKSSH----------VEKTNQ-KRVTEDFKWGEEESSKISPLKTPML MOUSEX_PE1950 ISOFORMIN EG---CCSGIQEPPRASR----------TVRTGL-QCPSNDFKLVDGESGRISRQRTPML MOUSEX_PE1951 ENSMUSG00000045180 EG---CCSGIQEPPRASR----------TVRTGL-QCPSNDFKLVDGESGRISRQRTPML MYOLUGS_3236_PE1 NOISO ------GTEDEEPQRARH----------GDRAGV-Q------RVAAGESGQISAHGTPLL ORNANULTRA462_6_PE4 ENSOANG00000009689 EG---CDSLCQQDY-TRPN---------DTSLQS-RPCRSDFKWAEEESDKISPRKTPML ORNANULTRA462_6_PE5 ISOFORMIN EG---WSEGLGDIRGASRV---------NETNRQ-IPDADYFKWAEEESDKISPRKTPML ORYLA2_17_PE12 NOISO RGEG-PSSDVKR---LFQ-----SSNH---KA---ASSQHQDPWLPHEDQRISSLKTPLL ORYLA4_32_PE17 NOISO ----GKH------QVTAAPE--------PSGRKM-RETSQEVRQPIPATNKISPQTTPML OTOGAGS_2886_PE1 NOISO EG---CSTGTQEPSGASL----------VDKASQ-PPRADSSRWAAGESSGVSPQKTPLL PANTRX_11_PE1 NOISO EG---CSAGAQEPPRASR----------AEKASQ--RLAASITWADGESSRICPQETPLL PIGX_6_PE3 NOISO ------AAGATELPSGSL----------LDKASL-KKVAGDFTWADQGGGEICPLQTPML POEGU1_20_PE6 NOISO QQ---EY-------VKDC----------VLMAEN-RSAQKDFRWGKDESSKISPQKTPML PONPYX_10_PE2 NOISO EG---CSAGAQEPPRASR----------AEKASQ--RLAASITWADGESSRICPQETPLL PTEVAGS_2083_PE1 NOISO GS---RSSGLEWPQRAGP----------SDRASA-KKVVDSFRCPDGESSKICPQ--PML RATX_PE414 ENSRNOG00000024322 EG---CCSGIHEPPRASH----------TVRAGL-QCPGNDFKLVDAESGRISRQRTPML RATX_PE415 ISOFORMIN EG---CCSGIHEPPRASH----------TVRAGL-QCPGNDFKLVDAESGRISRQRTPML SPETRGS_3166_PE1 NOISO EG---CFSGIQEPPRASR----------AEKASP-QKTAEGFQWAEGESSRISRQRTPML TARSYGS_4663_PE1 NOISO ES---CPMGTQEPPRASR----------TEKASQ-QKTAVGFKWADGESSRISPQETPLL TETNG3_PE72 ENSTNIG00000017158 ------EGDLKKPPPACQ-----STNH---KV---SPPRQAEPWSPQEDRRISPLKTPLL TETNG3_PE73 ISOFORMIN ------EGDLKKPPPACQ-----STNH---KV---SPPRQAEPWSPQEDRRISPLKTPLL TURTRGS_550_PE3 NOISO GG---HCEGAEEPPAAG-L---------VETASV-KRVAGGFAWDHV-GGEICPLQTPML MATCH CONSENSUS ???????????????????????????????????????????????????I????TP?L

AILMEGL194998_1_PE1 NOISO HSLTREGMRRPD---------NGQD--AGPERPPPFDTQVGKPTRRSDRFATTLRNEIQM ANOCA81_2_PE4 NOISO -----------------------------------------KPFERSDRFATTLRNEIQM BOVINX_88_PE9 NOISO HSLSRERACPPETRHK-------------DMAPAPPEALAGKPLRRSDRFATTLRNEIQQ CALJAX_9_PE1 ENSCJAG00000000928 HSLTQEGKHQPE---------SSPE--GSTATPAPFDAQVGKPTRRSDRFATTLRNEIQM CALJAX_9_PE2 ISOFORMIN HSLTQEGKHQPE---------SSPE--GSTATPAPFDAQVGKPTRRSDRFATTLRNEIQM CANFAX_7_PE3 NOISO HSLAQEGTCRPE---------NGQD--GGTERPPPFDAQVGKPTRRSDRFATTLRNEIQM CAVPO126_2_PE3 NOISO HSLSQEG----------------QL--GAMEKLPPFDAQVGRPARRSDRFATTLRNEIQL CHICK1_PE2106 NOISO HSLAQEGKKHSD---------GSPE--AVTERQPPFDNHLSKQARRSDRFATTLRNEIQM DANRE11_47_PE9 NOISO HSLAQESKKMAE---------NSITTASKGGSHESSDASSGKLGRRSDRYATTLRKEIQK DANRE6_32_PE4 NOISO YSLAQGHNDTDD---------CSNQIKSGSAQHEALDSLSSKQVRRNDRFATTLRNEIQM ECHTEGS_4788_PE1 NOISO HSLTQEGRKVRTGHHQDGGSGDPHT--GGLGKPRPFDAQVGKPIRRSDRFATTLRNEIQM FELCAGS_2696_PE1 NOISO HSLAREGARPPD---------DGPG--AGAERPPPFDGQVGRATRRSDRFATTLRNEVQM FUGRU13_1_PE137 ISOFORMIN HSLSLDTA-------------GQEP-------TSAIESLEGKQLRRSDRFATTLRNEIQM FUGRU13_1_PE138 ISOFORMIN HSLSLDTA-------------GQEP-------TSAIESLEGKQLRRSDRFATTLRNEIQM FUGRU13_1_PE139 ENSTRUG00000012349 HSLSLDTA-------------GQEP-------TSAIESLEGKQLRRSDRFATTLRNEIQM FUGRU13_1_PE140 ISOFORMIN HSLSLDTA-------------GQEP-------TSAIESLEGKQLRRSDRFATTLRNEIQM FUGRU57_1_PE17 NOISO HSLAQESIILTERQPATT------GGKSALENSDIMATGSGKSNRRSDRYATTLRNEIQQ GASACGROUPI_29_PE25 NOISO HSLAQESRSLATRAPAAS------T--ASLQEGDAAAAGSFKSNRRSDRYATTLRNEIQR GASACGROUPVIII_19_PE38 NOISO HFLSVDGDDAVA---------GQGE---ATRGPTSEESLDSKMARRSDRFATTLRNEIQM GORGOX_11_PE1 NOISO HSLTQEGRRRPE---------SSPE--DSATRPPPFDAHVGKPTRRSDRFATTLRNEIQM HORSEX_7_PE4 ISOFORMIN HLLAQEGTRRPE---------DSQE--GDPERPPPLDAQGGKPTRRSDRFATTLRNEIQM HORSEX_7_PE5 ENSECAG00000012150 HLLAQEGTRRPE---------DSQE--GDPERPPPLDAQGGKPTRRSDRFATTLRNEIQM HSX_PE143 ENSG00000146950 HSLTQEGKRRPE---------SSPE--DSATRPPPFDAHVGKPTRRSDRFATTLRNEIQM LOXAF94_6_PE2 NOISO HSLTQEDGRRPG---------HHQD--SGMGKPLPFDSQVGKPIRRSDRFATTLRNEIQM MACEUGS_5635_PE1 NOISO HSLAQEGKNRSE---------NSQD--ASIEKPLPFDAQVGKPARRSDRFATTLRNEIQL MACMUX_8_PE9 ENSMMUG00000006193 HSLTQEGKHRPE---------SSPE--DSATRPPPFDAHVGKPTRRSDRFATTLRNEIQM MICMUGS_799_PE3 NOISO HSLTQEGTCQPE---------NRQG--GGAAKPPTLDAQVGRATRRSDRFATTLRNEIQM MONDO7_34_PE7 ENSMODG00000017449 HSLAQEGKRRSA---------HSQE--ASVDKPAPFDAQVGKPTRRSDRFATTLRNEIQM MONDO7_34_PE8 ISOFORMIN HSLAQEGKRRSA---------HSQE--ASVDKPAPFDAQVGKPTRRSDRFATTLRNEIQM MOUSEX_PE1950 ISOFORMIN HSLTQDGTWRPG---------NSKD--CGNDKPPLFDAQVGKPTRRSDRFATTLRNEIQM MOUSEX_PE1951 ENSMUSG00000045180 HSLTQDGTWRPG---------NSKD--CGNDKPPLFDAQVGKPTRRSDRFATTLRNEIQM MYOLUGS_3236_PE1 NOISO HXXXXXXXXXXX---------XXXX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX ORNANULTRA462_6_PE4 ENSOANG00000009689 HSLAQEGKSQPE---------HCPG--ARPDKPPPFDGQVGKQARRSDRFATTLRNEIQM ORNANULTRA462_6_PE5 ISOFORMIN HSLAQEGKSQPE---------HCPG--ARPDKPPPFDGQVGKQARRSDRFATTLRNEIQM ORYLA2_17_PE12 NOISO HSLTQESWSLTAAAPAAV------P---------AQDAGSGKVNRRSDRYATTLRKEIQQ ORYLA4_32_PE17 NOISO HSLSVCAT-------------ARQD---HAVGGSSEEALETQQMARSNRFATTLRNEIQT OTOGAGS_2886_PE1 NOISO HSLAQEGTCQLE---------SSQG--GGTARPSPIEAQVGRPTRRSDRFATTLRNEIQM PANTRX_11_PE1 NOISO HSLTQEGKRRPE---------SSPE--DSATRPPPFDAHMGKPTRRSDRFATTLRNEIQM PIGX_6_PE3 NOISO HSLTREGARRPE---------PSFD--G-AAERLALEAPAGKPMRRSDRFATTLRNEIQL POEGU1_20_PE6 NOISO HSLAQEGKKQSD---------NNPE--VVSEQQTSFDTHLSKQARRSDRFATTLRNEIQM PONPYX_10_PE2 NOISO HSLTQEGKRRPE---------SSPE--DSATRPPPFDAHVGKPTRRSDRFATTLRNEIQM PTEVAGS_2083_PE1 NOISO HSLIQDSVQAP------------------------EGVQVGKPIRRSDRFATTLRNEIQL RATX_PE414 ENSRNOG00000024322 HSLTQDGAWRPG---------NSKD--CGNEKPPLLDAQVGKPTRRSDRFATTLRNEIQM RATX_PE415 ISOFORMIN HSLTQDGAWRPG---------NSKD--CGNEKPPLLDAQVGKPTRRSDRFATTLRNEIQM SPETRGS_3166_PE1 NOISO HSLTQEGMCQPE---------NGQD--GGTEKLPPFDAQVGKPTRRSDRFATTLRNEIQM TARSYGS_4663_PE1 NOISO HSLTQEGKRQPE---------NSRD--GSTMRPPPFDAQVGKPTRRSDRFATTLRNEIQM TETNG3_PE72 ENSTNIG00000017158 HSLAQEGQALSQRRPSSS------PLKCAPDSSDLGAPGGGKSNRRGDRYATALRNEIQQ TETNG3_PE73 ISOFORMIN HSLAQEGQALSQRRPSSS------PLKCAPDSSDLGAPGGGKSNRRGDRYATALRNEIQQ TURTRGS_550_PE3 NOISO HSLTQEGARRPE---------AGHE--GAPERPPP-EAPAGKPMRRSDRFATTLRNEIQL MATCH CONSENSUS HSL?????????????????????????????????????GK??RRSDRFATTLRNEIQ?

AILMEGL194998_1_PE1 NOISO RRARLQKSKSTVTLPGTGGAA---------EEASGWRAERGD--ATGAAPEGSF-PGTYR ANOCA81_2_PE4 NOISO KRAKMQKSRSTAALAGSTETE---------EYVENWK-PDSAEKINC-SSENSF-TNMYK BOVINX_88_PE9 NOISO RRARLQKSRSTATLASSAEEEGEVEDDVETEARGSWAQPVGA-------PETTFPSGTYK CALJAX_9_PE1 ENSCJAG00000000928 RRAKLQKSRSTVALTAAGDSE---------NTTGHWRAESGG--GT---QEGPL-AGTYK CALJAX_9_PE2 ISOFORMIN RRAKLQKSRSTVALTAAGDSE---------NTTGHWRAESGG--GT---QEGPL-AGTYK CANFAX_7_PE3 NOISO RRAKLQKSKSTVTLTGSGDAA---------EEAGSWRAERGG--ATSATPEGSF-TGTYK CAVPO126_2_PE3 NOISO RRAKLQKSKSTATLAEGSGAN---------AKAGSWQAQPG------VPSEGAF-SSTYK CHICK1_PE2106 NOISO RRAKLQKSRSTATLIGSSETE---------ECSENGK-PDAAENVNA-SPDTNF-TSTYK DANRE11_47_PE9 NOISO KRAQLQKSRSAATLTCSTEVE---------EDSDIWKSNET----STSSSDGSF-TNTYK DANRE6_32_PE4 NOISO RRAHLQKSQSAATLESPVETV---------EESALWKTTGTA----SPSSDGCF-SISYK ECHTEGS_4788_PE1 NOISO RRARLQKSKSSVTLAGTGEAE---------EDPAGWRAELGA--APGTPPEGSF-TNTYK FELCAGS_2696_PE1 NOISO RRANLHKSRSTVALAGDE-AA---------REAGGWQVEPGG--VPGASPEGSF-RGTYK FUGRU13_1_PE137 ISOFORMIN RKAQLQKSKSVSTLPDLEGEAD--------DDQDVWESKNA----TCVSAGGSF-TNTYK FUGRU13_1_PE138 ISOFORMIN RKAQLQKSKSVSTLPDLEGEAD--------DDQDVWESKNA----TCVSAGGSF-TNTYK FUGRU13_1_PE139 ENSTRUG00000012349 RKAQLQKSKSVSTLPDLEGEAD--------DDQDVWESKNA----TCVSAGGSF-TNTYK FUGRU13_1_PE140 ISOFORMIN RKAQLQKSKSVSTLPDLEGEAD--------DDQDVWESKNA----TCVSAGGSF-TNTYK FUGRU57_1_PE17 NOISO KRAQLQKSRSAATLTCDAEEE----------EAEDTRAPKT-----SPSSGVSF-SNTYK GASACGROUPI_29_PE25 NOISO KRAQLQKSRSAATLTCDVEDD----------EA--VGGART-----AVSSGVSS-SNTYK GASACGROUPVIII_19_PE38 NOISO RRAKLQKSISAAALPGTEGGGE--------NDQDVWKSPES-------APPASF-TGSYK GORGOX_11_PE1 NOISO HRAKLQKSRSTVALTAAGEAE---------DVTGRWRAGLGG--GT---QEGPL-AGTYK HORSEX_7_PE4 ISOFORMIN RRAKLQKSKSTVTLAGTSEGE---------EE------------AAGAGPEGSF-PGTYK HORSEX_7_PE5 ENSECAG00000012150 RRAKLQKSKSTVTLAGTSEGE---------EE------------AAGAGPEGSF-PGTYK HSX_PE143 ENSG00000146950 HRAKLQKSRSTVALTAAGEAE---------DGTGRWRAGLGG--GT---QEGPL-AGTYK LOXAF94_6_PE2 NOISO RRAKLQKSKSTVTLAGTDEPK---------EDPGGWRVELGA--VTGATPEGSF-TSTYK MACEUGS_5635_PE1 NOISO RRAKLQKSRSTATLTGTNEEE---------ECTDGWK-TETGENFNT-TSEGSF-NNTYK MACMUX_8_PE9 ENSMMUG00000006193 RRAKLQKSRSTVALTAAGEAE---------DATGRWRVKLGG--GA---QEGPF-AGTYK MICMUGS_799_PE3 NOISO RRAKLQKSKSTATLT--GDAE---------DAAGGWRAELGG--AASTPPEGPF-TGTYK MONDO7_34_PE7 ENSMODG00000017449 RRAKLQKSKSTATLTGANEEE---------EDADGWK-AEAGENFSASTAEGSF-NNTYK MONDO7_34_PE8 ISOFORMIN RRAKLQKSKSTATLTGANEEE---------EDADGWK-AEAGENFSASTAEGSF-NNTYK MOUSEX_PE1950 ISOFORMIN RRAKLQKSKSTVTLAGDSEAE---------DCAGDWRADVGA------VPEGSF-PSTYK MOUSEX_PE1951 ENSMUSG00000045180 RRAKLQKSKSTVTLAGDSEAE---------DCAGDWRADVGA------VPEGSF-PSTYK MYOLUGS_3236_PE1 NOISO XXXXXXXXXXXXXXXXXXXXX---------XXXXXXXXXXXX--XX---XXXXX-XXXXX ORNANULTRA462_6_PE4 ENSOANG00000009689 RRAKLQKSKSTASLTGESETE---------ECGDPWK-PESGD--------DSF-PSTYR ORNANULTRA462_6_PE5 ISOFORMIN RRAKLQKSKSTASLTGESETE---------ECGDPWK-PESGD--------DSF-PSTYR ORYLA2_17_PE12 NOISO KRAQLQKSRSAATLTCEPDED----------EPEEWRSVEL-----SASSGA----SSYK ORYLA4_32_PE17 NOISO RRARMQKSRSAAALPDAEPKAEP----EPRADPEEWRSAQ-----SSTSAEGSF-SNTYK OTOGAGS_2886_PE1 NOISO RRARLQKSRSTVALTSAGEGE---------DA-------------ASTPPEGPF-SGTYK PANTRX_11_PE1 NOISO HRAKLQKSRSTVALTAAGEAE---------DVTGRWRAGLGG--GT---QEGPL-AGTYK PIGX_6_PE3 NOISO RRARLQKSRSTATLAGPGAEEEEEEEE-EEAEVRGWGAHQAG--GAGTAPEATV-TSSYK POEGU1_20_PE6 NOISO RRAKLQKSRSTAALAGSSETE---------ECSETWK-PDSTENKRS-KCYRAL-LNKMK PONPYX_10_PE2 NOISO HRAKLQKSRSTVALTAAGEAE---------DATSRWRAGLGG--GA---QEGPL-AGTYQ PTEVAGS_2083_PE1 NOISO RRANLQKSRSSVTLAGPYEAE---------GEAAGCRAGVRA--AT---LEAAL-PGTYK RATX_PE414 ENSRNOG00000024322 RRAKLQKSKSTVTLAGDSEAE---------DCAGDWRVDVGA------VPEGSF-PSTYK RATX_PE415 ISOFORMIN RRAKLQKSKSTVTLAGDSEAE---------DCAGDWRVDVGA------VPEGSF-PSTYK SPETRGS_3166_PE1 NOISO RRAKLQKSKSTVTLAGASEAE---------DSASSWTAEVGG---T---LEGSF-SSTYK TARSYGS_4663_PE1 NOISO RRAKLQKSKSTVTLTAAGCAG---------DAASSWRAELGG--IT---PEGPF-TSTYK TETNG3_PE72 ENSTNIG00000017158 KRAQLQKSRSAATLTCDAEDE----------DGEELRASKV-----CPSSGVSF-SNTYK TETNG3_PE73 ISOFORMIN KRAQLQKSRSAATLTCDAEDE----------DGEELRASKV-----CPSSGVSF-SNTYK TURTRGS_550_PE3 NOISO RRARLQKSRSTATLAGAAEGD---------ETTAEAEARDWGVQPAGGPPEAAF-SSTYK MATCH CONSENSUS ?RA?LQKS?S???L???????????????????????????????????????????TYK

AILMEGL194998_1_PE1 NOISO EHVKEAQARVLRATSFKRRDLDPSPVDHYAGSLEHRAEEHGA---------DLDTVPLVR ANOCA81_2_PE4 NOISO DNLKEAQARVLKATSFQRRDLEASSADYLP----DRKTNNCNSS--PLAFVSEDESGFLE BOVINX_88_PE9 NOISO DHLKEAQARVLRATSFRRRDLDLSLADP-------------------------EPAPRVW CALJAX_9_PE1 ENSCJAG00000000928 DHLKEAQARVLRATSFKRRDLDPSPADPYPESLEHQMGDPDA---------VP----HFW CALJAX_9_PE2 ISOFORMIN DHLKEAQARVLRATSFKRRDLDPSPADPYPESLEHQMGDPDA---------VP----HFW CANFAX_7_PE3 NOISO DHLKEAQARVLRATSFKRRDLDPSPADHHAGSPEHRAEEHSA---------DPDTAPHFW CAVPO126_2_PE3 NOISO DHLKEAQARVLRATSFKRRDLDPSPADQYPGPPEHRAREHGAT---LSCPVEPDCAPHFW CHICK1_PE2106 NOISO DHLKEAQARVLRATSFKRRDLEPSPAEYPPR-SPERKAGSYNSS--LLALVSEDVSGFLE DANRE11_47_PE9 NOISO DHLKEAQAKVLQATSFMRKDLELPGNEVVSA----------------------------- DANRE6_32_PE4 NOISO DHLKEAQARVLQATSFRRKDLEPVLFEHPGTEGPTRKDVPP------------------S ECHTEGS_4788_PE1 NOISO DHLKEAQARVLRATSFKRRDLDPSPGEPFPVTSERRPE-------------NLDSDPHFL FELCAGS_2696_PE1 NOISO DHLKEAQARVLRATSFKRRDLEPSPADRPAGSAEPRTEEHST---------HLDAAPHFW FUGRU13_1_PE137 ISOFORMIN VNLKEAQARVLMATSFRRKDLEPVPLENPSVETIP----TYSSS----ALTCKDAPPLPP FUGRU13_1_PE138 ISOFORMIN VNLKEAQARVLMATSFRRKDLEPVPLENPSVETIP----TYSSS----ALTCKDAPPLPP FUGRU13_1_PE139 ENSTRUG00000012349 VNLKEAQARVLMATSFRRKDLEPVPLENPSVETIP----TYSSS----ALTCKDAPPLPP FUGRU13_1_PE140 ISOFORMIN VNLKEAQARVLMATSFRRKDLEPVPLENPSVETIP----TYSSS----ALTCKDAPPLPP FUGRU57_1_PE17 NOISO DHLKEVQAKVLQATSFQRRDLEPFGPEPLVG----------------------------- GASACGROUPI_29_PE25 NOISO DHLKEAQARVLQATSFQRRDLEPLGPEALAV----------------------------- GASACGROUPVIII_19_PE38 NOISO DHVKEAQARVLKATSFRRKDLEPVLLEHLAAEGLP----SYPSS----RKDVA---P-LP GORGOX_11_PE1 NOISO DHLKEAQARVLRATSFKRRDLDPNPGDLYPESLEHRMGDPDA---------VP----HFW HORSEX_7_PE4 ISOFORMIN DHLQEAQARVLRATSFKRRDLDPSPADHYTGLPDH-----ST---------DPDPVPRSW HORSEX_7_PE5 ENSECAG00000012150 DHLQEAQARVLRATSFKRRDLDPSPADHYTGLPDH-----ST---------DPDPVPRSW HSX_PE143 ENSG00000146950 DHLKEAQARVLRATSFKRRDLDPNPGDLYPESLEHRMGDPDT---------VP----HFW LOXAF94_6_PE2 NOISO DHLKEVQARVLRATSFKRRDLDPSPGDHCPVPPEHRPGDRDTS---SLYPLGLDAAPHFL MACEUGS_5635_PE1 NOISO DHLKEAQARVLRATSFKRRDLEPSSTDHYSKSSPER-----------LTLDSDSASHFFD MACMUX_8_PE9 ENSMMUG00000006193 DHLKEAQARVLRATSFKRRDLDPNPADLYPESLEHRMGGPDT---------VR----HFW MICMUGS_799_PE3 NOISO DHLKEAQARVLRATSFKRRDLDPNPVDEYPRSPEHRTGDPDI---------VP----PFW MONDO7_34_PE7 ENSMODG00000017449 DHLKEAQARVLRATSFKRRDLGPSSADHYSKSSPERKANGYSSS--FLLALDPDSASQFF MONDO7_34_PE8 ISOFORMIN DHLKEAQARVLRATSFKRRDLGPSSADHYSKSSPERKANGYSSS--FLLALDPDSASQFF MOUSEX_PE1950 ISOFORMIN EHLKEAQTRVLKATSFQRRDLDPTPADQYSGPSEHRTFDHSASSSLSSFPGEPDSAPRFC MOUSEX_PE1951 ENSMUSG00000045180 EHLKEAQTRVLKATSFQRRDLDPTPADQYSGPSEHRTFDHSASSSLSSFPGEPDSAPRFC MYOLUGS_3236_PE1 NOISO XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---------XX----XXX ORNANULTRA462_6_PE4 ENSOANG00000009689 GHLQEAQARVLRATSFQRRDLEGSPAGHYPRSSEHG-LGSCGSS--SCRPLDPETNSRLQ ORNANULTRA462_6_PE5 ISOFORMIN GHLQEAQARVLRATSFQRRDLEGSPAGHYPRSSEHG-LGSCGSS--SCRPLDPETNSRLQ ORYLA2_17_PE12 NOISO DHLKEAQARVLQATSFQRRDLEPLGADVL------------------------------- ORYLA4_32_PE17 NOISO DHLKEVQEKVLKATSFRRRDLEPVLLELSKEANHP----SSVHK------------NVDP OTOGAGS_2886_PE1 NOISO DHLKEAQARVLRATSFQRRDLDPHPVEQHSGSTEHRTGDPDS---------VP----QLW PANTRX_11_PE1 NOISO DHLKEAQARVLRATSFKRRDLDPNPGDLYPESLEHRMGDPDA---------VP----HFW PIGX_6_PE3 NOISO DHLKEAQARVLRATSFRRRDLEPSHVDPDTGP-------------------------RVR POEGU1_20_PE6 NOISO KI------KV--YTCLAPENMVISALKML--TTTEVIKMFHNSS--LVALVSEDVSGFLE PONPYX_10_PE2 NOISO DHLKEAQARVLRATSFKRRDLDPNPAHLYPESLEHRMGDPDA---------VP----HFW PTEVAGS_2083_PE1 NOISO DHLKEAQARVLRATSFKRRDLDPSPADRHAASLERRAGDPHE---------HPDTASRVA RATX_PE414 ENSRNOG00000024322 EHLKEAQTRVLKATSFQRRDLDPTPADQYPGPPEHRTCDHSASSSLSSFPGEPDSAPRLC RATX_PE415 ISOFORMIN EHLKEAQTRVLKATSFQRRDLDPTPADQYPGPPEHRTCDHSASSSLSSFPGEPDSAPRLC SPETRGS_3166_PE1 NOISO DHLKEAQARVLRATSFKRRDLDPNPVDQYPGSLEHRTGDPNS---------VP----HFC TARSYGS_4663_PE1 NOISO DHLKEAQARVLRATSFKRRDLDPNPADHYLGSPEHRTEDPDT---------VP----HFW TETNG3_PE72 ENSTNIG00000017158 DHLKEAQAKVLQATSFQRRDLEPFGPEPLVA----------------------------- TETNG3_PE73 ISOFORMIN DHLKEAQAKVLQATSFQRRDLEPFGPEPLVA----------------------------- TURTRGS_550_PE3 NOISO DHLKEAQARVLRATSFRRRDLEPCPSDPDTL-------------------------PRVW MATCH CONSENSUS ?HLKEAQARVL?ATSF?RRDL?P?????????????????????????????????????

AILMEGL194998_1_PE1 NOISO EGGLAK-PP---PPGA-GVPHVPRIGGRKRFTLEQKLKSYSEPEKMNEVGLSGDE-RPPQ ANOCA81_2_PE4 NOISO ARKSFK-H----NSPGSNVHHVPRIGARKRFTAEQKLKSYSEPEKINELGVSVDDYHSRR BOVINX_88_PE9 NOISO EGAPGARPPLCAA-GSGSGSGSARIGSRRRFTAEQKLKSYSEPEKMNAVGLTGDQ-SPAP CALJAX_9_PE1 ENSCJAG00000000928 EAGPAQ-PP---S-SAGGGPHLSRIGGRRRFTAEQKLKSYSEPEKMNEVGLTGGR-SPHQ CALJAX_9_PE2 ISOFORMIN EAGPAQ-PP---S-SAGGGPHLSRIGGRRRFTAEQKLKSYSEPEKMNEVGLTGGR-SPHQ CANFAX_7_PE3 NOISO EGGLAK-PP---PSGG-GMPHVLRIGGRKRFTVEQKLKSYSEPEKMNEVGLSGDY-RPHQ CAVPO126_2_PE3 NOISO EAGLTK-PA---SPGG-GPPQVSRVGGRKRFTAEQKLKSYSEPEKMNQVGLLGDC-SSHQ CHICK1_PE2106 NOISO ATQA-K-P----NPTGSGTHHVSRIGARKRFTTEQKLKSYSEPEKMNEVGMSEDECRAHC DANRE11_47_PE9 NOISO ----QL-P--------KRPGQVTRIGGRKRFPMDKKIHSFSEPDKINEVGVED------- DANRE6_32_PE4 NOISO SVSEVT-P----SKPTSGSNHVLRIGGRKRISAEKKVTSFSEPDKIHEVGADERST---- ECHTEGS_4788_PE1 NOISO EEGSSK-PS---SPGGAAVPHVPRIGGRRRFTVEQKLKSYSEPEKMHQVGLSGHC-RPRQ FELCAGS_2696_PE1 NOISO EGGLPK-PS---PSGG-GLPHVPRIGGRKRFTAQQKLKSYSEPEKMNEVGLAGPD-RPHR FUGRU13_1_PE137 ISOFORMIN VL-ESV-V----SKPGHAGAPVSRIGGRKRFSAEKKVRSFSEPDKIHEVGVSEDLSCL-- FUGRU13_1_PE138 ISOFORMIN VL-ESV-V----SKPGHAGAPVSRIGGRKRFSAEKKVRSFSEPDKIHEVGVSEDLSCL-- FUGRU13_1_PE139 ENSTRUG00000012349 VL-ESV-V----SKPGHAGAPVSRIGGRKRFSAEKKVRSFSEPDKIHEVGVSEDLSCL-- FUGRU13_1_PE140 ISOFORMIN VL-ESV-V----SKPGHAGAPVSRIGGRKRFSAEKKVRSFSEPDKIHEVGVSEDLSCL-- FUGRU57_1_PE17 NOISO -----K-------------TSNGRIRGRKRFPLAKRTHSFSEPDKIDKVGVEGEP----- GASACGROUPI_29_PE25 NOISO -----K-------------TTNGRFRGRKRFPLAKKTLSFSEPDKMDKVGVEGEP----- GASACGROUPVIII_19_PE38 NOISO TLSESA-M----SRAGPAGGQVTRIGSRKRFTAEKKVRSFSEPGQIHQVGVSSAPHQQ-- GORGOX_11_PE1 NOISO EAGLAQ-PP---S-STSGGPHPPRIGGRRRFTAEQKLKSYSEPEKMNEVGLTRGY-SPHQ HORSEX_7_PE4 ISOFORMIN EVSLAK-PP---SSAG-GMPHVPRIGGRRRFTVEQKLKSYSEPEKMHEVGLSGDH-RPPQ HORSEX_7_PE5 ENSECAG00000012150 EVSLAK-PP---SSAG-GMPHVPRIGGRRRFTVEQKLKSYSEPEKMHEVGLSGDH-RPPQ HSX_PE143 ENSG00000146950 EAGLAQ-PP---S-STSGGPHPPRIGGRRRFTAEQKLKSYSEPEKMNEVGLTRGY-SPHQ LOXAF94_6_PE2 NOISO EGDSAK-LS---LPGG-GVPHILRIGGRRRFTAEQKLKSYSEPEKIHEVGLSGNY-RPHQ MACEUGS_5635_PE1 NOISO GSQA-R-A----STSGNGMQHVPRIGGRKRFTAEQKLKSYSEPEKINEVGISGDYHNPCH MACMUX_8_PE9 ENSMMUG00000006193 EAGLAQ-PP---S-STGGGPHPPRIGGRRRFTAEQKLKSYSEPEKMNEVGLTRGY-SPHQ MICMUGS_799_PE3 NOISO ETGPSK-PA---S-SGGGGPLVPRIGGRKRFTAEQKLKSYSEPEKMNEVGLSGGC-GPRQ MONDO7_34_PE7 ENSMODG00000017449 DVSQTK-T----STSGNGVQHVSRIGGRKRFTAEQKLKSYSEPEKINEVGISGDYHHPCH MONDO7_34_PE8 ISOFORMIN DVSQTK-T----STSGNGVQHVSRIGGRKRFTAEQKLKSYSEPEKINEVGISGDYHHPCH MOUSEX_PE1950 ISOFORMIN ETGLAK-AP---SSGV-GVPHVLRIGGRKRFTAEQKLKSYSEPEKINEVGLSGDH-RPHP MOUSEX_PE1951 ENSMUSG00000045180 ETGLAK-AP---SSGV-GVPHVLRIGGRKRFTAEQKLKSYSEPEKINEVGLSGDH-RPHP MYOLUGS_3236_PE1 NOISO XXXXXX-XX---X-XXXXXXXXXXXXXXXXXXXXXXXXXXSEPEKMNEVGLSEDH-CPRQ ORNANULTRA462_6_PE4 ENSOANG00000009689 GVSRSK-P----ASSGIGLPPISRVGGRRRFTAEQKLRSYSEPEKIHEVGISEGY-NPRR ORNANULTRA462_6_PE5 ISOFORMIN GVSRSK-P----ASSGIGLPPISRVGGRRRFTAEQKLRSYSEPEKIHEVGISEGY-NPRR ORYLA2_17_PE12 NOISO -----K-------------VSNGRFRGRKRFHPAKRTHSFSEPDKMDKVGVEGGP----- ORYLA4_32_PE17 NOISO VLNQQG-T----GNSGLSSGQVSRIGGRKRFTAEKKVRCFSEPDKIHEVGVDQDPSGN-- OTOGAGS_2886_PE1 NOISO EAGLAK-TA---S-SGSGMPHISRIGGRKRFTAEQKLKSYSEPEKMNEVGLSGAY-GPHQ PANTRX_11_PE1 NOISO EAGLAQ-PP---S-STSGGPHPPRIGGRRRFTAEQKLKSYSEPEKMNEVGLTKGY-SPHQ PIGX_6_PE3 NOISO EVAPAR-PPSCATSGGGSALPAPRIGGRRRFTAAQKLKSYSEPEKMNEVGLAGDD-PPRR POEGU1_20_PE6 NOISO TTQA-K-P----NPTGSGTHHVSRIGARKRFTTEQKLKSYSEPEKMNEVGISEDECHAHC PONPYX_10_PE2 NOISO EAGLAQ-PP---S-STGGGPHPPRIGGRRRFTAEQKLKSYSEPEKMNEVGLTRGC-SPHQ PTEVAGS_2083_PE1 NOISO KVGLAR-SP---S-CAGGVSHVARIGGRKRLTAEQKLKSYSEPEKMNQVGLSGAQ-GPQ- RATX_PE414 ENSRNOG00000024322 EAGLAK-PP---SSAG-GVPHILRIGGRKRFTAEQKLKSYSEPEKINEVGLSGDH-SPHP RATX_PE415 ISOFORMIN EAGLAK-PP---SSAG-GVPHILRIGGRKRFTAEQKLKSYSEPEKINEVGLSGDH-SPHP SPETRGS_3166_PE1 NOISO EAGLAK-PP---S-SGGGMPHVPRIGGRKRFTAEQKLKSYSEPEKMNEVGLSVDC-SPHQ TARSYGS_4663_PE1 NOISO EVGLAK-QP---S-SGSGVPHIPRIGGRKRFTAEQKLKSYSEPEKMNEVGLSGGY-DPRQ TETNG3_PE72 ENSTNIG00000017158 -----K-------------PSAGRVRGRRRLPLAKRTHSFSEPDKMDKVGVEGEA----- TETNG3_PE73 ISOFORMIN -----K-------------PSAGRVRGRRRLPLAKRTHSFSEPDKMDKVGVEGEA----- TURTRGS_550_PE3 NOISO EAAPAR-L----PSSAGGALHAPRIAGRRRFTAEQKLKSYSEPEKMNEVGLAGDE-RPRQ MATCH *** ::. :* CONSENSUS ???????????????????????RIGGR?RF??E?K??S?SEP?K???VG??????????

AILMEGL194998_1_PE1 NOISO HPGTSEE-TMGTFADRWKFFEETSKPIHQRPGQRQ--ALCGFPKERLERPQTAGR---GY ANOCA81_2_PE4 NOISO RPTTSEE-ALGSFADRWKFFEETSKPAYQKSSQRH--TPYGRPEIQPPNPYR-NSQ--ES BOVINX_88_PE9 NOISO H-----DETLWTFADRWKFFEETSKPVGPQPGPRP--APCGFPREKPEMLWTVGPGKD-- CALJAX_9_PE1 ENSCJAG00000000928 HPRTSED-SMGTFADRWKFFEETSKPISQRPAQRQ--ALHGVPRDKLERPRTAGR---TC CALJAX_9_PE2 ISOFORMIN HPRTSED-SMGTFADRWKFFEETSKPISQRPAQRQ--ALHGVPRDKLERPRTAGR---TC CANFAX_7_PE3 NOISO HPDASEETVVGTFADRWKFFEETSRPIHQRPGQRQ--ALCGFPKERLERPQTAGH---GN CAVPO126_2_PE3 NOISO HPGTPED-CMGTFADRWKFFEETSKPVLQRPGHRQ--AACGLPREKAERPRTAGMAGPGG CHICK1_PE2106 NOISO HPETSEE-ALGSFADRWKFFEETSKPACRKPAQKP--TPHSLAEGLPERADRKAYG--GQ DANRE11_47_PE9 NOISO ------K-AGGSFADRYKFFEGSGKAVVQKPIPKQ--SLLGPTVDHSERKTGE------- DANRE6_32_PE4 NOISO ----MPE-NVAHLENQQRFFETTGKPVFPKPMPKQ--NLQISEDPRLSKPGGMHYS--AN ECHTEGS_4788_PE1 NOISO RPEPAED-TVGTFADRWKFFEETSRPVPQRPGRRQ--APSGLSREKAERQQTAGQ---GF FELCAGS_2696_PE1 NOISO HPGASED-AVGTFADRCKFFEESSRPIHQRPGQRQ--ALCGFPKEKLQRPRTAGH---GY FUGRU13_1_PE137 ISOFORMIN ------E-DLSSSLDQEKSFKESGKLGYFSPAQICIENFSKTKEGAPGS---------NG FUGRU13_1_PE138 ISOFORMIN ------E-DLSSSLDQEKSFKESGKLGYFSPAQICIENFSKTKEGAPGS---------NG FUGRU13_1_PE139 ENSTRUG00000012349 ------E-DLSSSLDQEKSFKESGKLGYFSPAQICIENFSKTKEGAPGS---------NG FUGRU13_1_PE140 ISOFORMIN ------E-DLSSSLDQEKSFKESGKLGYFSPAQICIENFSKTKEGAPGS---------NG FUGRU57_1_PE17 NOISO --------QTGSFGERRKFFE--NKPAFSRPVLKS--SHSANLSTDSAEAI--------- GASACGROUPI_29_PE25 NOISO --------HAGSFGERKKFFE--AKPAFSRPVLKS--SPGATPNADLSEVG--------- GASACGROUPVIII_19_PE38 NOISO ------Q-P----------CKEGGTPAVPNHAPHR--SSAGNPTEAETRGLAP-----TR GORGOX_11_PE1 NOISO HPRTSED-TVGTFADRWKFFEETSKPVPQRPAQKQ--ALHGIPRDKPERPRTAGR---TC HORSEX_7_PE4 ISOFORMIN HPGTSQE-TMGTFADRWKFFEETSRPVQQRPGQRQ--ALCGLSKEKLERPRTGGH---VC HORSEX_7_PE5 ENSECAG00000012150 HPGTSQE-TMGTFADRWKFFEETSRPVQQRPGQRQ--ALCGLSKEKLERPRTGGH---VC HSX_PE143 ENSG00000146950 HPRTSED-TVGTFADRWKFFEETSKPVPQRPAQKQ--ALHGIPRDKPERPRTAGR---TC LOXAF94_6_PE2 NOISO VPNRVED-TVGTFADRRKFFEETSRSAHQRPEQRQ--ALCGFPREKPERLQTAGH---GY MACEUGS_5635_PE1 NOISO YPNTSGE-AMGSFADRWKFFEETSKPSHHRPGQRQ--AIYGLPKEQIDRPKKL-----RT MACMUX_8_PE9 ENSMMUG00000006193 HPRTSED-TVGTFADRWKFFEETSKPVPQRPAQRQ--VLHGILRDKPERPWTVGR---TC MICMUGS_799_PE3 NOISO LPRTPED-TVGTFADRWKFFEETSKPLPQRPGQRQ--APRVLPR---ERPWTAGR---GC MONDO7_34_PE7 ENSMODG00000017449 YPSTSGE-AMGSFADRCKFFEETSKPSHRRPAQRQ--AIYGLPKEQPDRPGRKS----HG MONDO7_34_PE8 ISOFORMIN YPSTSGE-AMGSFADRCKFFEETSKPSHRRPAQRQ--AIYGLPKEQPDRPGRKS----HG MOUSEX_PE1950 ISOFORMIN TVRTPED-TVGTFADRWKFFEETSKSLLQKAGHRQ--VHCGLPREKAERPQTGHH---EC MOUSEX_PE1951 ENSMUSG00000045180 TVRTPED-TVGTFADRWKFFEETSKSLLQKAGHRQ--VHCGLPREKAERPQTGHH---EC MYOLUGS_3236_PE1 NOISO H---SED-TVGTFADRWKFFEETSRLVPQRPRSRQ--ALPGVPKEKPDRPRATRL---GD ORNANULTRA462_6_PE4 ENSOANG00000009689 RPDTSEE-TLASFADRWKFFEETSKPSHQRPAQNP--TASGPWKGPPTGKV-------HG ORNANULTRA462_6_PE5 ISOFORMIN RPDTSEE-TLASFADRWKFFEETSKPSHQRPAQNP--TASGPWKGPPTGKV-------HG ORYLA2_17_PE12 NOISO --------QMGSEDEG-KVFQ--AKPTFARPAPKP--APTDSNQTHQTQ----------- ORYLA4_32_PE17 NOISO ------T-SSPGNQQ-----------ELTSAEPFCKQVPVQSHDKIRGRNVAP-----HS OTOGAGS_2886_PE1 NOISO HPRTPED-TMGSFADRWKFFEETSKLVPQGPGQRQ--VPHAFLREKLERPQPAGR---GR PANTRX_11_PE1 NOISO HPRTSED-TVGTFADRWKFFEETSKPVPQRPAQKQ--ALHGILRDKPERPRTAGR---TC PIGX_6_PE3 NOISO YPGPPDE-TVRTFADRWKFFEETSKPTGQRPGRRP--GPCGFPKEKPERPQTAGPG---N POEGU1_20_PE6 NOISO RPKISEE-ALGSFADRWKFFEETSKPAFRKSSQKP--GPHGLAEGQPERTERK-----AQ PONPYX_10_PE2 NOISO HPRTSED-TVGTFADRWKFFEETSKPVSQSPAQKQ--ALHGIPRDKPERPWTVGR---TC PTEVAGS_2083_PE1 NOISO ----PEE-TVGTFADRCKFFEETSRPVSQRPGPRQ--ALSGTLKEK--QAWATGH---GG RATX_PE414 ENSRNOG00000024322 TIRTSED-SVGTFADRWKFFEETSKSLLQKPGHRQ--AFCGIPREKAERPQTQGH---EC RATX_PE415 ISOFORMIN TIRTSED-SVGTFADRWKFFEETSKSLLQKPGHRQ--AFCGIPREKAERPQTQGH---EC SPETRGS_3166_PE1 NOISO HPTSPED-TVGTFADRWKFFEETSKPLLQRPGQRQ--ALCGVPREKVERPRTAGH---RS TARSYGS_4663_PE1 NOISO HPRTSED-TVGTFADRWKFFEETSKPISQQPGQRQ--ALHGVPREKLERPRTAVR---PN TETNG3_PE72 ENSTNIG00000017158 --------QTGSFGERRRFFE--SKPAFSRPVMKC--SHSASLNADCGETS--------- TETNG3_PE73 ISOFORMIN --------QTGSFGERRRFFE--SKPAFSRPVMKC--SHSASLNADCGETS--------- TURTRGS_550_PE3 NOISO RPAPPDE-TVRTFADRWKFFEETSKPVGQRSELRP--APCGFPKEKPERPWTAG------ MATCH CONSENSUS ????????????F?DR?KFFEE????????P?????????????????????????????

AILMEGL194998_1_PE1 NOISO EGAEPWFQERARTTSFGENPSGHR-----------KAGKG-GKLEP-PQRLGTFAEYQAS ANOCA81_2_PE4 NOISO EAEGSWHERRMRSASFGVENMLENVH---------YNSHQ-EKSGQ-PQRLETFAEYQAS BOVINX_88_PE9 NOISO -------------------------------------GK-AGRPIP-PERLGTFAEYQAS CALJAX_9_PE1 ENSCJAG00000000928 EGTE----PWLCATSLGESLSAHS-----------TVEKA-GPSDP-PRRLGTFAEYQAS CALJAX_9_PE2 ISOFORMIN EGTE----PWLCATSLGESLSAHS-----------TVEKA-GPSDP-PRRLGTFAEYQAS CANFAX_7_PE3 NOISO EGADPSFQKRPRTTSFGENPSGPR-----------RAGKV-GKLEP-PQRLGTFAEYQAS CAVPO126_2_PE3 NOISO ENTEPRLQKRSRAPSFGEILNGYR-----------KVENP-GKLDP-PQRLGTFAEYQAS CHICK1_PE2106 NOISO EGDESWHERRGRAASVGLETAHAPKGSFHHGSSSKAADRT-VKSEQ-PQRLGTFAEYQAQ DANRE11_47_PE9 NOISO -GES-----------IPRVLLK----------QSKSSHSD-LNADE-QQRLGTFAEYEAT DANRE6_32_PE4 NOISO S---DMAGRN-----NGE-SSTPIEHHINEGLDGPNSVNH-QALLE-QQRLGTFAEYEAK ECHTEGS_4788_PE1 NOISO EGEETWLRTRARTTSFGESASSCR-----------KAGKG-EIADPSPQRLGTFAEYQAS FELCAGS_2696_PE1 NOISO EGAEPWFQNRAHTTSFGENPSSHG-----------KTANM-GKPEP-PQRLGTFAEYQAS FUGRU13_1_PE137 ISOFORMIN ETEVTIKGRSSTE--YPQE--------VTGG--PQPPNKP-PSVPD-QQRLGTFAEYEAK FUGRU13_1_PE138 ISOFORMIN ETEVTIKGRSSTE--YPQE--------VTGG--PQPPNKP-PSVPD-QQRLGTFAEYEAK FUGRU13_1_PE139 ENSTRUG00000012349 ETEVTIKGRSSTE--YPQE--------VTGG--PQPPNKP-PSVPD-QQRLGTFAEYEAK FUGRU13_1_PE140 ISOFORMIN ETEVTIKGRSSTE--YPQE--------VTGG--PQPPNKP-PSVPD-QQRLGTFAEYEAK FUGRU57_1_PE17 NOISO ------KDKTPTEESKAAA-HT-----SDPS---V--AHE-QAPQE-QQRLGTFAEYQAT GASACGROUPI_29_PE25 NOISO ------KPKDRVPCAGGEV-HP-----SALR---LR-PGH-EQVLE-QQRLGSFAEYQAT GASACGROUPVIII_19_PE38 NOISO ETEDPLKGARSRV--STAE--------VQEG--PHS-AHR-QGVQD-QQRLGTFAEYEAR GORGOX_11_PE1 NOISO EGTE----PWSRTTSLGDSLNAHS-----------AAEKA-GTSDP-PRRLGTFAEYQAS HORSEX_7_PE4 ISOFORMIN EDAEPCFQKRAHTTSFGENADGHR-----------TAGKL-GKSEP-PQRLGTFAEYQAS HORSEX_7_PE5 ENSECAG00000012150 EDAEPCFQKRAHTTSFGENADGHR-----------TAGKL-GKSEP-PQRLGTFAEYQAS HSX_PE143 ENSG00000146950 EGTE----PWSRTTSLGDSLNAHS-----------AAEKA-GTSDL-PRRLGTFAEYQAS LOXAF94_6_PE2 NOISO EGTEPWFLRRGRTTSFGENPSSHR-----------KAEKV-GKFEP-PQRLGTFAEYQAS MACEUGS_5635_PE1 NOISO CGREQWYQKRTRTSSFGEDLNYSS----------SKVEKV-GKSEQ-PQRLGTFAEYQAS MACMUX_8_PE9 ENSMMUG00000006193 EGTE----PWSRTTSLGDSLNAHS-----------TAEKT-GTSDP-PQRLGTFAEYQAS MICMUGS_799_PE3 NOISO DAAE----PRPRTSSFGESLGGHR-----------KADKA-GKLEP-PQRLGTFAEYQAS MONDO7_34_PE7 ENSMODG00000017449 HGGEPWYQKRTRTSSFGETLNYPS----------GKAEKV-GKSEQ-PQRLGTFAEYQAS MONDO7_34_PE8 ISOFORMIN HGGEPWYQKRTRTSSFGETLNYPS----------GKAEKV-GKSEQ-PQRLGTFAEYQAS MOUSEX_PE1950 ISOFORMIN ESTEPWFQKRSLATSCGEILS-DR-----------KVEKASEKLNP-PRRLGTFAEYQAS MOUSEX_PE1951 ENSMUSG00000045180 ESTEPWFQKRSLATSCGEILS-DR-----------KVEKASEKLNP-PRRLGTFAEYQAS MYOLUGS_3236_PE1 NOISO QGAEPRPQDRARTTSFGENADGPR-----------KAGRT-GKSEP-PQRLGTFAEYQAS ORNANULTRA462_6_PE4 ENSOANG00000009689 PEGTDWHQKKTRTASFGEGLSSGS----------SRAHEV-ENCQQ-PQRLGTFAEYQAS ORNANULTRA462_6_PE5 ISOFORMIN PEGTDWHQKKTRTASFGEGLSSGS----------SRAHEV-ENCQQ-PQRLGTFAEYQAS ORYLA2_17_PE12 NOISO -------EKG--------L-SN-----DDIH---LSPGRS-PASLE-QQRLGTFAEYQAT ORYLA4_32_PE17 NOISO AAEDTLRGGARSE----------------TA--EGAPHHA-PSAYD-NQRLGTFAEYEAR OTOGAGS_2886_PE1 NOISO EGTE----PCSRSSSFGESLVSHR-----------KAEKV-GKLVA-PRRLGTFAEYQDS PANTRX_11_PE1 NOISO EGTE----PWSRTTSLGDSLNAHS-----------AAEKA-GTSDP-PRRLGTFAEYQAS PIGX_6_PE3 NOISO G------------------------------------GK-AGRSDP-PQRLGTFAEYQAS POEGU1_20_PE6 NOISO ERVELWYERRGRVASVGLETAHAS-----------KDSRV-GKSAQ-PLRLGTFAEYEAS PONPYX_10_PE2 NOISO EGTE----PWSRTTSLGDSLNAHS-----------AAERA-GTSDP-PRRLGTFAEYQAS PTEVAGS_2083_PE1 NOISO EGSEPRLQEPARSTPSAKYVRGPS-----------RATKV-GKLEP-LRWFGSFAEYEAS RATX_PE414 ENSRNOG00000024322 ESTEPWFQKRSRATSCGEILSEDR-----------KVEKASEKLNP-PRRLGTFAEYQAS RATX_PE415 ISOFORMIN ESTEPWFQKRSRATSCGEILSEDR-----------KVEKASEKLNP-PRRLGTFAEYQAS SPETRGS_3166_PE1 NOISO EGADSGFQTRSRATSFGEILSGHR-----------EAEKF-GKLDP-PQRLGTFAEYQAS TARSYGS_4663_PE1 NOISO EGLE----PWSRTTSFGESLNDHR-----------KTEKA-GKLEP-LQRLGTFAEYQAS TETNG3_PE72 ENSTNIG00000017158 ------KEKSPSEDTAPA---------ADAG---A--APQ-QASQE-QQRLGTFAEYQAT TETNG3_PE73 ISOFORMIN ------KEKSPSEDTAPA---------ADAG---A--APQ-QASQE-QQRLGTFAEYQAT TURTRGS_550_PE3 NOISO ---------------------------------PGKEGKV-GRSDP-PQRLGTFAEYQAS MATCH : :****: CONSENSUS ?????????????????????????????????????????????????RLGTFAEY?A?

AILMEGL194998_1_PE1 NOISO WREQKTALEARSTGRYHSADDILDAGLEQHERPQYIHGRSRSSPSTDLYTQPKSCENKEK ANOCA81_2_PE4 NOISO WKEQRKPLETRSSGRYHSADNILDAGHEQLEKSQYTHERSRSSPSTDFYKKVTTSPLRKA BOVINX_88_PE9 NOISO WREQRKVPEARGGGRYHSTDNILDVGVDQEERPQYVHERSRSSPSTDLYKQDASMEPRWE CALJAX_9_PE1 ENSCJAG00000000928 WKEQRKPLEARSSGRCHSADDILDVGLDPHERPPHVHGRSRSSPSTDHYKQEASVEPRRQ CALJAX_9_PE2 ISOFORMIN WKEQRKPLEARSSGRCHSADDILDVGLDPHERPPHVHGRSRSSPSTDHYKQEASVEPRRQ CANFAX_7_PE3 NOISO WREQRRALEARSSGRYHSADDILDAGLDQHERPQYIHGRSRSSPSTDLYKQEAAIEPQQQ CAVPO126_2_PE3 NOISO WKEQKKPLEAISAGRCHSADDILDAALDQHQRPQYVHERSRSSPSTDHYVQEASVEPLRQ CHICK1_PE2106 NOISO WKEQRKPIEARSSGRYHSAVSLVDAYLTMQM--IY--KSRDSSPGNTHLE-TEEVPVEVR DANRE11_47_PE9 NOISO WNLQKKQVERRNTGRYHSAENILDSGLEESNSALCVHERSRSSPSADFYGQKLPLPPRKL DANRE6_32_PE4 NOISO WNTQRKTTEPRVSGRYHSADNILDTGKERRSNPTCVHERSRSSPSADFYGQKLPPQEKKS ECHTEGS_4788_PE1 NOISO WKEQRKPVEARGSSRYHSADDILDVGLNQRERAQYLHERSRSSPSTEHYTEGVSVEAQRP FELCAGS_2696_PE1 NOISO WREQRNALEARSSGRYHSADDILDAGLDQHERPQYVHGRSRSSPSTDPYKQEAAIEPQQQ FUGRU13_1_PE137 ISOFORMIN WSTQEKKPETKDSGRYRSVDDILNPGPAERSPLNCFHERSRSSPSTDLYGQDTDS----- FUGRU13_1_PE138 ISOFORMIN WSTQEKKPETKDSGRYRSVDDILNPGPAERSPLNCFHERSRSSPSTDLYGQVRTITDRRS FUGRU13_1_PE139 ENSTRUG00000012349 WSTQEKKPETKDSGRYRSVDDILNPGPAERSPLNCFHERSRSSPSTDLYGQVRTITDREN FUGRU13_1_PE140 ISOFORMIN WSTQEKKPETKDSGRYRSVDDILNPGPAERSPLNCFHERSRSSPSTDLYGQ--------- FUGRU57_1_PE17 NOISO WNKYKKCSDVKSQGRYHSTENILDTDTE--ETSLCIHERSRSSPSADFYTQASTLNYRRD GASACGROUPI_29_PE25 NOISO WSQQKKSAEAQKQGRFHSAENILDAEGE--EKAACIHERSRSSPSADLYTQERPSQPAEQ GASACGROUPVIII_19_PE38 NOISO WSAQNPPPETRASGRYRSADNILDPGPEERTKTTCFHERSRSSPSADIYGRKIQVPARRF GORGOX_11_PE1 NOISO WKEQRKPLEARSSGRCHSADDILDVSLDPQERPQHVHGRSRSSPSTDHYKQEASVELRRQ HORSEX_7_PE4 ISOFORMIN WREQRNALEARSSGRYHSADDILDAGLDQHERPQYIHERSRSSPSTDLYKQEASVEPRRQ HORSEX_7_PE5 ENSECAG00000012150 WREQRNALEARSSGRYHSADDILDAGLDQHERPQYIHERSRSSPSTDLYKQEASVEPRRQ HSX_PE143 ENSG00000146950 WKEQRKPLEARSSGRCHSADDILDVSLDPQERPQHVHGRSRSSPSTDHYKQEASVELRRQ LOXAF94_6_PE2 NOISO WKEQREPLETRSSGRYHSADDILDVGLNQHERPQYMHARSRSSPSTDHYKEEVSVESRRQ MACEUGS_5635_PE1 NOISO WKEQRKPLEARSSGRYHSADDILDASLEQHDKPQYIHERSRSSPSTEHYKQEPSAGVRRQ MACMUX_8_PE9 ENSMMUG00000006193 WKEQRKPLEARSSGRCHSADDILDVGLDPHERPQHVHGRSRSSPSTDHYKQEASVELRRQ MICMUGS_799_PE3 NOISO WKEQRKPLEARSSGRYHSADDILDAGLDQHERPRYLHERSRSSPSTDHYKQEPSVEPQRQ MONDO7_34_PE7 ENSMODG00000017449 WKEQRKPLEARSSGRYHSADDILDASLEQHEKPQYIHERSRSSPSTEHYKQEPSAGVRRQ MONDO7_34_PE8 ISOFORMIN WKEQRKPLEARSSGRYHSADDILDASLEQHEKPQYIHERSRSSPSTEHYKQWLPPH---- MOUSEX_PE1950 ISOFORMIN WKEQKKPLEARSSGRYHSADDILDAGLDQQQRPQYIHERSRSSPSTDHYSQEVPVEPNRQ MOUSEX_PE1951 ENSMUSG00000045180 WKEQKKPLEARSSGRYHSADDILDAGLDQQQRPQYIHERSRSSPSTDHYSQEVPVEPNRQ MYOLUGS_3236_PE1 NOISO WRKQSKGPEARGSGRYHSADDILDVGLDQQERLQYVHERSRSSPSTDLYKQEAPIEPRRQ ORNANULTRA462_6_PE4 ENSOANG00000009689 WKEQRKPLEARSSGRYHSADDILDVVLEQNEKPQYVHERSRSSPSTDHYKQEASAGVRRQ ORNANULTRA462_6_PE5 ISOFORMIN WKEQRKPLEARSSGRYHSADDILDVVLEQNEKPQYVHERSRSSPSTDHYKQEASAGVRRQ ORYLA2_17_PE12 NOISO WNKQKKTAEAKTPGKFHSAENILDAGAD--ETPVCVHERSRSSPSADFYPQVRSMKISSP ORYLA4_32_PE17 NOISO WSKQRKAPEKKPSGRYHSADNIVDSTPE-DSDKTCFHERSRSSPSAHIYGQDSRTQDIIR OTOGAGS_2886_PE1 NOISO WKEQRKPLEARSXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXEASVEPRRQ PANTRX_11_PE1 NOISO WKEQRKPLEARSSGRCHSADDILDVSLDPQERPQHVHGRSRSSPSTDHYKQEASVELRRQ PIGX_6_PE3 NOISO WREQRKAPEARSAGRYHSADDILEVGLDQQERPPYIHERSRSSPSTDLYKQEASVDLRRE POEGU1_20_PE6 NOISO WKEPWKPVEPRGSGRYHSADNILDTGHEQHGKSQYTHERSRSSPSTDFYKQVQVRPDTSA PONPYX_10_PE2 NOISO WKEQRKPLEARSSGRCHSADDILDVSLDPHERPQHVHGRSRSSPSTDHYKQEASVELRRQ PTEVAGS_2083_PE1 NOISO WRRQKQAQEVKGSGRYHSADDILDAGLDQHSGLQYVHARSQSSPSGDVCKQEASIEPRQP RATX_PE414 ENSRNOG00000024322 WKEQKKSLEARSSGRYHSADDILDAGLDQQQRPQYIHERSRSSPSTDHYSQEVPVEPNRQ RATX_PE415 ISOFORMIN WKEQKKSLEARSSGRYHSADDILDAGLDQQQRPQYIHERSRSSPSTDHYSQEVPVEPNRQ SPETRGS_3166_PE1 NOISO WKEQRKPLEAKSAGRYHSADDILDVGLDQHHRPQYVHERSRSSPPTDHYTQEVAVKPRRQ TARSYGS_4663_PE1 NOISO WKEQRKPLESRSSGRYHSADDILDAGLDQHERPQYVHERSRSSPSTDHYKQEASVEQRRQ TETNG3_PE72 ENSTNIG00000017158 WNKCKKRPEGTSQGRCHSTENILDADTQ--ETSQCIHERSRSSPSADFYTQASAFESSSA TETNG3_PE73 ISOFORMIN WNKCKKRPEGTSQGRCHSTENILDADTQ--ETSQCIHERSRSSPSADFYTQASAFESSSA TURTRGS_550_PE3 NOISO WREQRKAPEARSSGRYHSADNILDVGLDQHERPQYIHGRSRSSPSTDLYKQEASVEVRRQ MATCH * : CONSENSUS W??Q?K??E????GR?HSAD?ILD????????????H?RSRSSPS?D?Y?Q?????????

AILMEGL194998_1_PE1 NOISO NNSLRT----FF-KNSSSTH-THTHTQVSSLGTMTALDRCGKTY-MDLIPSNDKPS---- ANOCA81_2_PE4 NOISO KEEKDN----SS------------------------------------------------ BOVINX_88_PE9 NOISO AGDPEE----HT-ELSSAAPAEDRSPTPRIAGEDIA-GHCRSRPALTCRLVF---C---- CALJAX_9_PE1 ENSCJAG00000000928 AGDPGE----HREEFPS----EEGQSTPRQADAWCREGSPGSQRH---PPSQSAPN---- CALJAX_9_PE2 ISOFORMIN AGDPGE----HREEFPS----EEGQSTPRQADAWCREGSPGSQRH---PPSQSAPN---- CANFAX_7_PE3 NOISO VGDPGE----RR-ELSSAVWAEEGHPS---LR-QADDAQCPEDS-TTAQQDFQKPS---- CAVPO126_2_PE3 NOISO PGNSGG----HR-ETPASTVCVR-------------EAHCTPS----------------- CHICK1_PE2106 NOISO RQA-ED----LK------------------------------------------------ DANRE11_47_PE9 NOISO PLDSPPEAKDQQEAHISSASEKEHNALNI---------------------SKS-QESITM DANRE6_32_PE4 NOISO ADCFKS----EKS----------------------------------------------- ECHTEGS_4788_PE1 NOISO AEDPAE----HG-EQHPCPAAQEDSSTLGVASTQHQEN-SPSTS-VEL----PHPC---- FELCAGS_2696_PE1 NOISO VGDAGE----HR-QLSAAVRAEEGRPNPRQA-----DVRRPASG-AAGQQDSRTPA---- FUGRU13_1_PE137 ISOFORMIN --------------------C----ELNKRQRLNV-----GEASD---PVPEGERQAEAM FUGRU13_1_PE138 ISOFORMIN RDNS-S------------------------------------------------------ FUGRU13_1_PE139 ENSTRUG00000012349 DCFP-P----KRFSSLNPPSC----FLSFYWDTDS-----CEASD---PVPEGERQAEAM FUGRU13_1_PE140 ISOFORMIN ------------------------------------------------------------ FUGRU57_1_PE17 NOISO I---QI----PIF-IRVNLS-RLDKSLLQNVP-SSWE------------D--------PP GASACGROUPI_29_PE25 NOISO ---------------SQSLS-RVERSLLEPCNDPLWRS--G-------SL--------SL GASACGROUPVIII_19_PE38 NOISO ETEYSPAEGTPAERLVAATGCDNTVSLAAPRDPGRRSDGVGETSG---PLGHSE------ GORGOX_11_PE1 NOISO AGEPGE----PREELPSAVRAEEGQSTPRQADAQCQEGSPGSQQH---PPSQKAPN---- HORSEX_7_PE4 ISOFORMIN AEDPGE----HK-ELSPTVRAEEGPAAVGNTVL--------------------------- HORSEX_7_PE5 ENSECAG00000012150 AEDPGE----HK-ELSPTVRAEEGRSNPH------------------------------- HSX_PE143 ENSG00000146950 AGDPGE----PREELPSAVRAEEGQSTPRQADAQCREGSPGSQQH---PPSQKAPN---- LOXAF94_6_PE2 NOISO AEDPAD----FK-TRNVCSLDAFEG--------------CISPR---------------- MACEUGS_5635_PE1 NOISO ADDSGE----DRNYIRSKISTDEGNSNLRPVDTEHQGESPEGKRD---PLYKQ------- MACMUX_8_PE9 ENSMMUG00000006193 AGDPGE----HREELPFAVRAKEGQSTLRQADVQCWEGSPGSQQH---PPSQNAPN---- MICMUGS_799_PE3 NOISO AEDARE----HR-ELPSIVHAEEGRSTPRQADAQCQEGSAGTGRH---PPSQK------- MONDO7_34_PE7 ENSMODG00000017449 TDDSGE----DRNYIRSQISPDEGHFTLRQTDTEHPGESPGKQVD---PSDPNR------ MONDO7_34_PE8 ISOFORMIN ------------------------------------------------------------ MOUSEX_PE1950 ISOFORMIN AEDSGD----HK-EAILCTLQAEEG--------------CSAPS---------------- MOUSEX_PE1951 ENSMUSG00000045180 AEDSGD----HK-EAILCTLQAEEG--------------CSAPS---------------- MYOLUGS_3236_PE1 NOISO AEDPGE----HR-EHPSTVPAEDGGPAPRQADAQCPEDGPGAHRG---LA---------- ORNANULTRA462_6_PE4 ENSOANG00000009689 AEDYRA----DREPISSKTRTDEGNSTWRQADAEPQRASPEEERY---WLDQNV------ ORNANULTRA462_6_PE5 ISOFORMIN AEDYRA----DREPISSKTRTDEGNSTWRSSPSEPI------------------------ ORYLA2_17_PE12 NOISO WRDPED----QGI-WKQRKSAALHGSDVQTQEIK-------------------------- ORYLA4_32_PE17 NOISO RKAE-R----PRRFLLSRGFLESEEEVDHEAEIQIRPFQPHESRR---PLSQS--LCRAL OTOGAGS_2886_PE1 NOISO AGDPRE----CR-EPPSAVCAEEGQSTLRQADAPYPEGSLGTGRR---PLNHSPWK---- PANTRX_11_PE1 NOISO AGDPGE----PRKELPSTVRAEEGQSTP-------------------------------- PIGX_6_PE3 NOISO AEEPRE----QR-ELFSAVLAEEGRPPQRSNQMAPQ------------------------ POEGU1_20_PE6 NOISO ------------------------------------------------------------ PONPYX_10_PE2 NOISO AGDPGE----PREELPSAVRAEEGQSTLRQADAQCREGSPGSQQH---PPSQNAPN---- PTEVAGS_2083_PE1 NOISO AEESAE----HR-ELSSTAWAEERRPALRQAHAQCAEDRPGAQW--------GLWE---- RATX_PE414 ENSRNOG00000024322 AEDSGG----QK-EALLCTLQAEEG--------------CSAPS---------------- RATX_PE415 ISOFORMIN AEDSGG----QK-EALLCTLQAEEG--------------CSAPS---------------- SPETRGS_3166_PE1 NOISO SEEPSG----HQEAVLSTVCAEEGQSAVXXXXXXXXXXXXXXXXX---XXXXXXXX---- TARSYGS_4663_PE1 NOISO AEDPGE----HREELPHTVCAEEGQSTLRQADAQCQEGSPGTQRR---PPSQNLQN---- TETNG3_PE72 ENSTNIG00000017158 FSGREI----PGL-L--------------------------------------------- TETNG3_PE73 ISOFORMIN FSGREI----PGL-LQLDET-E--GK----FT-SCFRM--C-------PR--------PG TURTRGS_550_PE3 NOISO TEDPGA----RRE-LSSSVQAEEGRPTPRQASAACAEDSPGAQRD---PQQPSQ------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

AILMEGL194998_1_PE1 NOISO --------------QL------------SK--PPPTWEAPDTPQ-EARSRAGTLPRDYRY ANOCA81_2_PE4 NOISO ------------------------------------------------------------ BOVINX_88_PE9 NOISO --------------WD------------MMDKQGPVVEPADCSE-KNKMHSGETFHPFRL CALJAX_9_PE1 ENSCJAG00000000928 --------------PP------------AFSELSHSQGAPELPQ-EVRGRAGTLPRDYRY CALJAX_9_PE2 ISOFORMIN --------------PP------------AFSELSHSQGAPELPQ-EVRGRAGTLPRDYRY CANFAX_7_PE3 NOISO --------------QP------------PK--PSPAWEAPEVPQ-EARSRAGTLPRDYRY CAVPO126_2_PE3 NOISO ------------------------------------------------------------ CHICK1_PE2106 NOISO ------------------------------------------------------------ DANRE11_47_PE9 NOISO SILDNSVEPLGYNQKS--------------------------------------RSDTKQ DANRE6_32_PE4 NOISO ------------------------------------------------------------ ECHTEGS_4788_PE1 NOISO --------------AK------------DQSPPAQPELPHDAPE-KGRCRAGTLPRDYRY FELCAGS_2696_PE1 NOISO --------------QL------------GQ--PSPAWGAPEVPP-EARGRAGTLPRDYRS FUGRU13_1_PE137 ISOFORMIN SRTGWPIPPQNYPNLPQVKLIQGCNGSPLFPDRGSS---------DCKVREK--SVEFE- FUGRU13_1_PE138 ISOFORMIN ------------------------------------------------------------ FUGRU13_1_PE139 ENSTRUG00000012349 SRTGWPIPPQNYAK---------------FPDRGSS---------DCKVREK--SVEFE- FUGRU13_1_PE140 ISOFORMIN ------------------------------------------------------------ FUGRU57_1_PE17 NOISO S-------QQ-----S---SGSSGLQILLRMKF-------YLI-L---------TARLPY GASACGROUPI_29_PE25 NOISO I-------QSGYSSAA---RGTRCTRGLYVCKF-------VFT-LTSR---GKAERTLRF GASACGROUPVIII_19_PE38 NOISO --------------EVFYSALSECDGGLSSGG------------SGCGGGGGQPESEYDV GORGOX_11_PE1 NOISO --------------PP------------AFSELSHCRGAPELPR-EGRGRAGTLPRDYRY HORSEX_7_PE4 ISOFORMIN ------------------------------------------------------------ HORSEX_7_PE5 ENSECAG00000012150 ------------------------------------------------------------ HSX_PE143 ENSG00000146950 --------------PP------------TFSELSHCRGAPELPR-EGRGRAGTLPRDYRY LOXAF94_6_PE2 NOISO ------------------------------------------------------------ MACEUGS_5635_PE1 NOISO ---------------------NSKSTEP-------SHRASGLPQ-ESRGRSGTLPSDYRY MACMUX_8_PE9 ENSMMUG00000006193 --------------PP------------TFSEPSHSQGAPELPQ-EGRGRAGTLPRDYRY MICMUGS_799_PE3 NOISO --------------PP------------ASSESSHTWKAPAPPR-EGRGRAGTLPRDYRY MONDO7_34_PE7 ENSMODG00000017449 -----------------PSKLRPFEPCQ-------PREPLALPQ-ESRGRSGTLPSDYRY MONDO7_34_PE8 ISOFORMIN ----------------------PHTPCE-------E------------------------ MOUSEX_PE1950 ISOFORMIN ------------------------------------------------------------ MOUSEX_PE1951 ENSMUSG00000045180 ------------------------------------------------------------ MYOLUGS_3236_PE1 NOISO --------------PG------------PGSEPSRAPEAPEVPQ-EGRGRAGTLPRDYRY ORNANULTRA462_6_PE4 ENSOANG00000009689 -----------------LGHWKSCGAAH-------PREPVASPR-ESRGRAGTLPNDYRF ORNANULTRA462_6_PE5 ISOFORMIN ------------------------------------------------------------ ORYLA2_17_PE12 NOISO ---------------I---THSQC-----------------------R---QNAQTQFTY ORYLA4_32_PE17 NOISO SIMD----------PPLRSRLAAGDGQPSAEQEGEPRQTWVSPKFSGDGEEN--PAEFK- OTOGAGS_2886_PE1 NOISO --------------PP------------TSSEFPD-------AR-EGRSRAGTLPRDYRY PANTRX_11_PE1 NOISO ------------------------------------------------------------ PIGX_6_PE3 NOISO ------------------------------------------------------------ POEGU1_20_PE6 NOISO ------------------------------------------------------------ PONPYX_10_PE2 NOISO --------------PP------------AFSELSHSRGAPELPQ-EGRGRAGTLPRDYRY PTEVAGS_2083_PE1 NOISO --------------PP------------QVPEQSPAQEAPELPL-EGGGRAETLPRDYRY RATX_PE414 ENSRNOG00000024322 ------------------------------------------------------------ RATX_PE415 ISOFORMIN ------------------------------------------------------------ SPETRGS_3166_PE1 NOISO --------------XX------------XXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXX TARSYGS_4663_PE1 NOISO --------------PS------------TVSESSHPQEAPQLPR-EGRSRAGTLPRDYRY TETNG3_PE72 ENSTNIG00000017158 ------------------------------------------------------------ TETNG3_PE73 ISOFORMIN T-------IL-----T---ASRAAAGKLKHRRH-------GSA-S---------TARLPY TURTRGS_550_PE3 NOISO -----------------VSESAGS--------------RALVPP-EGRDWAG--TCDYRY MATCH CONSENSUS ????????????????????????????????????????????????????????????

AILMEGL194998_1_PE1 NOISO PEETLGPGPHV----PSA----P--PSALHTRGQDPRPVN--------TAPLPKK----- ANOCA81_2_PE4 NOISO ------------------------------------------------------------ BOVINX_88_PE9 NOISO SHQNSNNNNNDKVFTQAC----KYMYSCTLYRDANALSLV--------TFPSLKKKQN-- CALJAX_9_PE1 ENSCJAG00000000928 SEESTPADLG-----PRA----QSPSSPLHAQGQDSWPVS--------SALLTKR----- CALJAX_9_PE2 ISOFORMIN SEESTPADLG-----PRA----QSPSSPLHAQGQDSWPVS--------SALLTKR----- CANFAX_7_PE3 NOISO PEETLHPGPQV----QSA-------PSALHTRGQDPRPVN--------TTPLTKK----- CAVPO126_2_PE3 NOISO ------------------------------------------------------------ CHICK1_PE2106 NOISO ------------------------------------------------------------ DANRE11_47_PE9 NOISO PAPITSQHLQVP-MSEQLLPKNNGLIPQHKELETT------------------------- DANRE6_32_PE4 NOISO --------------------------PCQQDKNST--------------------SKGP- ECHTEGS_4788_PE1 NOISO PVEVESPANLG----PPA----PSVPSSLPDRERDTRLSS--------ASSVTKR----- FELCAGS_2696_PE1 NOISO SER----------------------ASAPHTRGQEPRPLS--------AAPVPKQ----- FUGRU13_1_PE137 ISOFORMIN -R--YSRLPPTP-MTGANPDSKQRAAPATENHRPTSVSHSPKESKDHSQAEPL---SGPR FUGRU13_1_PE138 ISOFORMIN ------------------------------------------------------------ FUGRU13_1_PE139 ENSTRUG00000012349 -R--YSRLPPTP-MTGANPDSKQRAAPATENHRPTSVSHSPKESKDHSQAEPL---SGPR FUGRU13_1_PE140 ISOFORMIN ------------------------------------------------------------ FUGRU57_1_PE17 NOISO QHDHSSEPAP------SA-PKNEGPVPIHADHKTKAEEDS-----PAHATHP-------- GASACGROUPI_29_PE25 NOISO QSDLSP---Q------SA-PRDRGPVPGLPDHRTKADAAR-----PPDTIRS-------- GASACGROUPVIII_19_PE38 NOISO PEDSSSPTQGPP-A-------------AAPGRRTTRTSASEPNTGPPRSPAAS-RGPSPL GORGOX_11_PE1 NOISO SEESTPADLG-----PRA----QSPGSPLHARGQDSWPVI--------SALLSKK----- HORSEX_7_PE4 ISOFORMIN ------------------------------------------------------------ HORSEX_7_PE5 ENSECAG00000012150 ------------------------------------------------------------ HSX_PE143 ENSG00000146950 SEESTPADLG-----PRA----QSPGSPLHARGQDSWPVS--------SALLSKR----- LOXAF94_6_PE2 NOISO ------------------------------------------------------------ MACEUGS_5635_PE1 NOISO SEENAPSD-------LEAHAKNESVNPSSQDREEDSWWI--------DSAPFS-KRRGP- MACMUX_8_PE9 ENSMMUG00000006193 SEESIPADLG-----PRA----HSPGSPLHARGQDSWPVS--------SALLAKR----- MICMUGS_799_PE3 NOISO PEESTPADSG-----PLA----R---------GRDSRPLS--------A----------- MONDO7_34_PE7 ENSMODG00000017449 SEENEKEGAQVPDAPQEAPAQGDGVLPCPQAREEDSRW----------------KRRGP- MONDO7_34_PE8 ISOFORMIN ------------------------------------------------------------ MOUSEX_PE1950 ISOFORMIN ------------------------------------------------------------ MOUSEX_PE1951 ENSMUSG00000045180 ------------------------------------------------------------ MYOLUGS_3236_PE1 NOISO SEERTPPGPG-----SQA----QSGLSAPHAGGQDPRPVS--------AAPLAKR----- ORNANULTRA462_6_PE4 ENSOANG00000009689 SKETLPE----------APAKGQGLCPPQQARGEVSHPT--------DPTALN-RRRGP- ORNANULTRA462_6_PE5 ISOFORMIN ------------------------------------------------------------ ORYLA2_17_PE12 NOISO AKAGKPPLN--------------SYVAGLNRCLGSPSLPK-----P-ELSSA-------- ORYLA4_32_PE17 NOISO -N--DSPPLAPP-MTGANLDSRQGAAPAALSHRPTSFSHSAAESGPSQSDERS-HTAGRK OTOGAGS_2886_PE1 NOISO PEEGPPADSG-----PQI----W---------GQDSRPV--------------------- PANTRX_11_PE1 NOISO ----------------RA----QSPGSPLHARGQDSWPVS--------SALLSKR----- PIGX_6_PE3 NOISO ------------------------------------------------------------ POEGU1_20_PE6 NOISO ------------------------------------------------------------ PONPYX_10_PE2 NOISO SEESTPADLG-----PRA----QSPGSPLHAQGQDSWPVR--------SALLSKR----- PTEVAGS_2083_PE1 NOISO SEHPAAADPP-----PWA----GSAG-AEQPPGQGAWAVS--------TVPLPKR----- RATX_PE414 ENSRNOG00000024322 ------------------------------------------------------------ RATX_PE415 ISOFORMIN ------------------------------------------------------------ SPETRGS_3166_PE1 NOISO XXXXXXXXXX-----XXX----XXXXXXXXXXXXXXXXXX--------XXXXXXX----- TARSYGS_4663_PE1 NOISO SEENIPADSG-----PQT----QCISSPPQARGQDSWLVS--------AAPLTKR----- TETNG3_PE72 ENSTNIG00000017158 ------------------------------------------------ATPP-------- TETNG3_PE73 ISOFORMIN QHDGSPDAAV------SA-STN-----------GGAEADS-----PAQATPP-------- TURTRGS_550_PE3 NOISO PETRAADRPAAP------HARGXXAR-----------------------------PAGP- MATCH CONSENSUS ????????????????????????????????????????????????????????????

AILMEGL194998_1_PE1 NOISO -PAPQRPP--PPKREPR--QLKGLA-----GGTPGTAPLSAPSKPLPPP------SPEAL ANOCA81_2_PE4 NOISO ----------------------ASLA------ASSESSLSVPNRSIQSL------SSPAA BOVINX_88_PE9 NOISO -MAPQNKT---PGSQKN--KFKKKN-----YSG--ALLKYSCS--------------AVF CALJAX_9_PE1 ENSCJAG00000000928 -PAPQRPP--PPKREPR--RYRAT------DSTPADVPLAIPSRPFPTP------SPASL CALJAX_9_PE2 ISOFORMIN -PAPQRPP--PPKREPR--RYRAT------DSTPADVPLAIPSRPFPTP------SPASL CANFAX_7_PE3 NOISO -PAPQRPP--PPKREPR--PFKGLA-----GGTPVATHLGAPSKSLPPP------SPEAL CAVPO126_2_PE3 NOISO ------------------------------------------------------------ CHICK1_PE2106 NOISO ----------------------KHLD------AILNTVLAIASVS-LSS------AQPRD DANRE11_47_PE9 NOISO ---------------------CPIMAS--------------LEVRI-QT------FSPEP DANRE6_32_PE4 NOISO --VGEE------------------------------------------------------ ECHTEGS_4788_PE1 NOISO -LAPLQSP--PPKHEPR--RSKGQD-----TTG--DTAEGACSRHCP----------NPV FELCAGS_2696_PE1 NOISO -PAPRRPPPPPPKREPG--QLGGLA-----GGTPSG----------PQP------SPEAP FUGRU13_1_PE137 ISOFORMIN RKSLEKPP--PPRCPEI--NSHEPFTS-----S--------QSEAF---------SHCSP FUGRU13_1_PE138 ISOFORMIN ------------------------------------------TEEM-------------- FUGRU13_1_PE139 ENSTRUG00000012349 RKSLEKPP--PPRCPEI--NSHEPFTS-----S--------QSEAF---------SHCSP FUGRU13_1_PE140 ISOFORMIN ------------------------------------------SEAF---------SHCSP FUGRU57_1_PE17 NOISO -SVPRSLS-PSAGSQDSLPTPRSHLVPE---TTS--TSLSSSQKKFPSGAQADSASFQPL GASACGROUPI_29_PE25 NOISO -SA-QNPP-PPPQAQGLLPPPRPHLGPE---TTS--S-----SQEFLAGARADPTAPQPP GASACGROUPVIII_19_PE38 NOISO RRRPAG-G--PPRHPDA--RRSTPMSP-----------------------------PPVP GORGOX_11_PE1 NOISO -PAPQRPP--PPKREPR--RYRAT------DGVPADAPLAVLGRPFPTP------SPASL HORSEX_7_PE4 ISOFORMIN ------------------------------------------------------------ HORSEX_7_PE5 ENSECAG00000012150 ------------------------------------------------------------ HSX_PE143 ENSG00000146950 -PAPQRPP--PPKREPR--RYRAT------DGAPADAPVGVLGRPFPTP------SPASL LOXAF94_6_PE2 NOISO ------------------------------------------------------------ MACEUGS_5635_PE1 NOISO --APQRPP--PPRRDTS--KYRTSVG------SSSEYLLAVPSRPVQSQ------SPNSP MACMUX_8_PE9 ENSMMUG00000006193 -PAPQRPP--PPKREPR--RYRAT------DSAPADAPLAVLGRPFPTP------SPASL MICMUGS_799_PE3 NOISO -----------ASRAPR--KCRGP------EGAPAPAHLVASGRALSVP---------PE MONDO7_34_PE7 ENSMODG00000017449 --APQRPP--PPKRDAS--RHRRQDGPPDA------------------------------ MONDO7_34_PE8 ISOFORMIN ------------------------------------------------------------ MOUSEX_PE1950 ISOFORMIN ------------------------------------------------------------ MOUSEX_PE1951 ENSMUSG00000045180 ------------------------------------------------------------ MYOLUGS_3236_PE1 NOISO -PAPQRPP--PPKREPR--PFRGPA-SATPAGTPAGNHLAVPSRPLPPP------PSPAR ORNANULTRA462_6_PE4 ENSOANG00000009689 --VPQRPP--PPKLDGN--KYRRPDVSTPSSGTSPESLWVAPGKTFLPH------SP--- ORNANULTRA462_6_PE5 ISOFORMIN ------------------------------------------------------------ ORYLA2_17_PE12 NOISO -LPFRSLP-PNSSCTTH--NVNQIMHPK---EQQ--MSFHKEN----KLTNKKTACFRPD ORYLA4_32_PE17 NOISO PSAPETLP--PAASPEP--ASCESLTG-----S--------LSEVS---------FCRSP OTOGAGS_2886_PE1 NOISO -----------PPHQPR--KCRGP------EGASAREHLAAPRGALPAP---------PE PANTRX_11_PE1 NOISO -PAPQRPP--PPKREPR--RYRAT------DGAPADAPLAVLGRPFPTP------SPASL PIGX_6_PE3 NOISO ------------------------------------------------------------ POEGU1_20_PE6 NOISO ----------------------PPLG------TSSESLLAAASRPFLSS------SPSSA PONPYX_10_PE2 NOISO -PAPQRPP--PPKREPG--RYRAT------DGVPADAPLAVLGRPFPTP------SPASL PTEVAGS_2083_PE1 NOISO -PAPQRPP--PPKA---------------PAGTPAAGHLASPSKPLPPP------SPAAL RATX_PE414 ENSRNOG00000024322 ------------------------------------------------------------ RATX_PE415 ISOFORMIN ------------------------------------------------------------ SPETRGS_3166_PE1 NOISO -XXXXXXX--XXXXXXX--XXXXX------XXXXXXXXXXXXXXXXXXX------XXXXX TARSYGS_4663_PE1 NOISO -PVPQRPP--PSKREPR--KYRSP------DSTPADIHLAIPSRPFPPP------SPASL TETNG3_PE72 ENSTNIG00000017158 -LGPRSLS-PSAGSQDSPPTPSSHLAPE---TAP--SSLSSSCQRVPP--EADPASFQPE TETNG3_PE73 ISOFORMIN -LGPRSLS-PSAGSQDSPPTPSSHLAPE---TAP--SSLSSSCQRVPP--EADPASFQPE TURTRGS_550_PE3 NOISO --APD-----------------------------PEVLVLGPS----------------- MATCH CONSENSUS ????????????????????????????????????????????????????????????

AILMEGL194998_1_PE1 NOISO EVCVDRLSLSHSPCALVEKL-----SSAQPEDGV---RAAGEHDKRHVDEHIACPKREAL ANOCA81_2_PE4 NOISO --------------------------------------------NVHL-EEKPHLRSEPV BOVINX_88_PE9 NOISO QVYSRRIQLYRPQPPKRELWPPPGDTPSRPHTSVASSEAVDTRSTRRVEEPTARPWREAL CALJAX_9_PE1 ENSCJAG00000000928 DVCVAHLSLSHSPSVFS---------STQPQDTP--KTTTCERVGQHVSADTSCPLPEAL CALJAX_9_PE2 ISOFORMIN DVCVAHLSLSHSPSVFS---------STQPQDTP--KTTTCERVGQHVSADTSCPLPEAL CANFAX_7_PE3 NOISO EACVDRLSLSHIPCASVEKL-----SSTQPEDSL---RAAGEHSRQHVDEHTACPKREAL CAVPO126_2_PE3 NOISO ----------------QSVL-----SSAQPQDTP--KATACERDSQHVKEDVLYPQPEAL CHICK1_PE2106 NOISO --------------------------------------------GQHL-EEKTHLKSKSV DANRE11_47_PE9 NOISO TQ--ERLRLNTSEPLDGDMH-------------A--QV--DEHKSERMLSPIPHNSAGSP DANRE6_32_PE4 NOISO ------------------------------------------EQHQELVPPPFPPPPPPV ECHTEGS_4788_PE1 NOISO ALDVDRLPLFQSPPTLS-----------RPHCAP--PAAPCEHDRPRMN----------- FELCAGS_2696_PE1 NOISO DACAPRPALGQR-------------------------PVDGERAGRHVDGHPAGHESQAP FUGRU13_1_PE137 ISOFORMIN SVNTNPAFVTSH-TAEEESE-----QG-----KR--LVDKGPEAVQHLSTSNPELESSP- FUGRU13_1_PE138 ISOFORMIN ----------IV-CSKEESE-----QG-----KR--LVDKGPEAVQHLSTSNPELESSP- FUGRU13_1_PE139 ENSTRUG00000012349 SVNTNPAFVTSH-TAEEESE-----QG-----KR--LVDKGPEAVQHLSTSNPELESSP- FUGRU13_1_PE140 ISOFORMIN SVNTNPAFVTSH-TAEEESE-----QG-----KR--LVDKGPEAVQHLSTSNPELESSP- FUGRU57_1_PE17 NOISO SSTD------THQQTAS--RSPVGTAPVG---FPQLSMTSGADTGRGAAQGGEETEPPRP GASACGROUPI_29_PE25 NOISO SGCD------RHHAAG--------PASGR---LPSS--TSG----GGG--GNEAE--KQP GASACGROUPVIII_19_PE38 NOISO REKPSPAALPTPPTLRRES----------------------------PST------ATKD GORGOX_11_PE1 NOISO DVYVARLSLSHSPSVFS---------SAQPQDTP--KATVCERGSQHVSGDASRPLPEAL HORSEX_7_PE4 ISOFORMIN -------------------------------------RSAVPTDKHALNVDLTAPQTTCP HORSEX_7_PE5 ENSECAG00000012150 ---------------------------------------LPPQSEQHHNPDRWYPRAACP HSX_PE143 ENSG00000146950 DVYVARLSLSHSPSVFS---------SAQPQDTP--KATVCERGSQHVSGDASRPLPEAL LOXAF94_6_PE2 NOISO ----------------NSQV-----CS----------LLQSESSQHHVNEDPPKP----- MACEUGS_5635_PE1 NOISO DVYVNPLTLPQSPSTFSEKL-----TSAQLQDSR--QPASSENDCQPLNEETSNLKPEAV MACMUX_8_PE9 ENSMMUG00000006193 DVCVARLSLSHSPSVFS---------SAQPQDIP--KAAACERGSQHVSGDTSLPLPEAP MICMUGS_799_PE3 NOISO DTCAARLSLPHGPSVSR---------SAQPQDAP--EAAACQ----HVSRGAPRPEPQAP MONDO7_34_PE7 ENSMODG00000017449 --AAHPPALAQSPCALGEQP-----GGPPPQDSG--PPASSEGDCQPLNEDAAPP----- MONDO7_34_PE8 ISOFORMIN --SYSRKDCILSPCALGEQP-----GGPPPQDSG--PPASSEGDCQPLNEDAAPP----- MOUSEX_PE1950 ISOFORMIN -------------------------------------AQPQ--DSQHVNEDTTFPQPETQ MOUSEX_PE1951 ENSMUSG00000045180 ----------------SSVL-----SS----------AQPQ--DSQHVNEDTTFPQPETQ MYOLUGS_3236_PE1 NOISO SPCVLAEK-------PS---------GAQPADGP--KAP-GEQDRQHVDEHPACPKREAL ORNANULTRA462_6_PE4 ENSOANG00000009689 -------------GP----V-----ASPPPQEPR--QATTTENGFQHLDEEKLCLKPEPV ORNANULTRA462_6_PE5 ISOFORMIN ------------------------------------------IDSEHLDEEKLCLKPEPV ORYLA2_17_PE12 NOISO DEAKSVSNYKTTEGEAG--EPTVGSCGLQ---------EPGPR-------PQDQSRPCQR ORYLA4_32_PE17 NOISO TAQPSSSLHPTH-AVRGDSE-----QG-----RG--LVDKGQGAVHHPSKPSPPPASSPP OTOGAGS_2886_PE1 NOISO DTCAARLSLPHGPSVS----------SAHPQDVP--EAAAR----QHVSQAATCPEPQAL PANTRX_11_PE1 NOISO DVYVARLSLSHSPPVFS---------SAQPQDTP--KATVCERGSQHVSGDASRPLPEAL PIGX_6_PE3 NOISO -------------------------------------------DRIRASESSIFPQEKTQ POEGU1_20_PE6 NOISO ---------------------------------Q--QVSSTENVCQHL-EEKTHLKSE-- PONPYX_10_PE2 NOISO DACVARLSLSHSPSVFS---------SAQPQDTP--KTTVRERGSQHVSGGASCPLPEAL PTEVAGS_2083_PE1 NOISO EVCVDRLSRSCSPCVPAEKP-----SGAQPTHGP--KGP-EEPRRQHVDERAACPKPEAL RATX_PE414 ENSRNOG00000024322 ----------------SSVL-----SS----------AQPQ--DSQHVNEDPTSPQPEAQ RATX_PE415 ISOFORMIN ----------------SSVL-----SS----------AQPQ--DSQHVNEDPTSPQPEAQ SPETRGS_3166_PE1 NOISO XXXXXXXXXXXXXXXXX---------XXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXX TARSYGS_4663_PE1 NOISO DVCEARLPLSHSPSVVS---------SSQPQDAP--RAAACEHDSQHVSGDTPRPPPESL TETNG3_PE72 ENSTNIG00000017158 SSTD------AHQHPAS--SPPVGPAPPG---FPPLSLTPGPDARRGAAEDREDRE---- TETNG3_PE73 ISOFORMIN SSTD------AHQHPAS--SPPVGPAPPG---FPPLSLTPGPDARRGAAEDREDRE---- TURTRGS_550_PE3 NOISO -------ASPAAAPALG--R-----SRAPPARGG--PRAAGEPAGQHVDERAGWPRREAP MATCH CONSENSUS ????????????????????????????????????????????????????????????

AILMEGL194998_1_PE1 NOISO LP-SKFR--PLQTSAMETSRSPSPQFAPQKLTDKPPLLIQEENPTR-------------- ANOCA81_2_PE4 NOISO LA-STY--RGHLKPEMEASRSPSPQFAPQKLTDKPPVAVQDDNPA--------------- BOVINX_88_PE9 NOISO LP-APFR--PLQTSAMDSSRSPSPQFAPQKLTDKPPLLIQDENAAR-------------- CALJAX_9_PE1 ENSCJAG00000000928 LP-PKQQHLRLQTATMETSRSPSPQFAPQKLTDKPPLLIQDEDSTR-------------- CALJAX_9_PE2 ISOFORMIN LP-PKQQHLRLQTATMETSRSPSPQFAPQKLTDKPPLLIQDEDSTR-------------- CANFAX_7_PE3 NOISO LP-SRFR--PLHMSTMETSRSPSPQFAPQKLTDKPPLLIQDENSTR-------------- CAVPO126_2_PE3 NOISO PS-SKFQ--HLRAFAMETSRSPSPQFAPQKLTDKPPLLIHDEHSTR-------------- CHICK1_PE2106 NOISO LTSSKY--RYLQKPHMETSRSPSPQFAPQKLTDKPPVSVQDDNPA--------------- DANRE11_47_PE9 NOISO I--PPKQKADLTVTSASRTRSPSPQFFPQRLTDEPPANVYKKDPC--------------- DANRE6_32_PE4 NOISO V-LPTQQTAGPTQPTMDGQRSPSPQFAPQRLTDKPPVSVSSQDEA--------------- ECHTEGS_4788_PE1 NOISO ---LQAW--QPPAATMETSRSPSPQFAPQKLTDKPPLLIQDESATR-------------- FELCAGS_2696_PE1 NOISO LP-SSLR--APRPAAMETSRSPSPQFAPQKLTDRPPLLVQDESSTX-------------- FUGRU13_1_PE137 ISOFORMIN -----L--ASSGPASMEGRRSPSPQFSPQRLSDKPPVFVQDELSN--------------- FUGRU13_1_PE138 ISOFORMIN -----L--ASSGPASMEGRRSPSPQFSPQRLSDKPPVFVQDELSN--------------- FUGRU13_1_PE139 ENSTRUG00000012349 -----L--ASSGPASMEGRRSPSPQFSPQRLSDKPPVFVQDELSN--------------- FUGRU13_1_PE140 ISOFORMIN -----L--ASSGPASMEGRRSPSPQFSPQRLSDKPPVFVQDELSNSYHPGHVVFVESAL- FUGRU57_1_PE17 NOISO LP---S-----PPLSADGARTPSPQFGAQRLTDKPPAAFAQDDSPLSLRSLLGTENVL-- GASACGROUPI_29_PE25 NOISO LS---SCTAARSLPATDQARSPSPQ---------------RDDSPLGLLRSGDSR-WT-G GASACGROUPVIII_19_PE38 NOISO V--RPP--PTPGPLAMEEQRSPSPHFSPQRLSDKPPASLQDEDPP--------------- GORGOX_11_PE1 NOISO LP-PKQQHLRLQTATMETSRSPSPQFAPQKLTDKPPLLIQDEDSTR-------------- HORSEX_7_PE4 ISOFORMIN FP-SQCR--PLPPAAMDTSRSPSPQFAPQKLTDKPPLLIQDENSTR-------------- HORSEX_7_PE5 ENSECAG00000012150 FP-SQCR--PLPPAAMDTSRSPSPQFAPQKLTDKPPLLIQDENSTR-------------- HSX_PE143 ENSG00000146950 LP-PKQQHLRLQTATMETSRSPSPQFAPQKLTDKPPLLIQDEDSTR-------------- LOXAF94_6_PE2 NOISO ------G--HPQRATMETSRFPSPQFAPQKLTDKPPLLIQDESSTR-------------- MACEUGS_5635_PE1 NOISO L-SSKY--R--HLHLMESSRSPSPQFAPQKLTDKPPLLVQDENSA--------------- MACMUX_8_PE9 ENSMMUG00000006193 LP-PKQQHLRLQTATMETSRSPSPQFAPQKLTDKPPLLIQDEDSTR-------------- MICMUGS_799_PE3 NOISO LP-PACRALPLRT-AMETSRSPSPQFAPQKLTDKPPLLMQDEESTR-------------- MONDO7_34_PE7 ENSMODG00000017449 ---PKY--RLLPQSGMESSRSPSPQFAPQKLTDKPPLLVQDENSA--------------- MONDO7_34_PE8 ISOFORMIN ---PKY--RLLPQSGMESSRSPSPQFAPQKLTDKPPLLVQDENSASFYRHLLCAKTLDN- MOUSEX_PE1950 ISOFORMIN LS-SKCQ--HLQTSAMETSRSPSPQFAPQKLTDKPPLLIHEDNSAR-------------- MOUSEX_PE1951 ENSMUSG00000045180 LS-SKCQ--HLQTSAMETSRSPSPQFAPQKLTDKPPLLIHEDNSAR-------------- MYOLUGS_3236_PE1 NOISO LS-SKFR--PLQTSAMETSRSPSPQFL-QKLTDKPLLLIQDDS----------------- ORNANULTRA462_6_PE4 ENSOANG00000009689 LSSKFQHRHHLQKAAMEMSRSPSPQFAPQKLTDKPPVLLQDENPT--------------- ORNANULTRA462_6_PE5 ISOFORMIN LSSKFQHRHHLQKAAMEMSRSPSPQFAPQKLTDKPPVLLQDENPT--------------- ORYLA2_17_PE12 NOISO LP---NRTLPRP--SEHQVRSWEEE--------EEAHHLKQPPSDLTLEEKG-RRLETNR ORYLA4_32_PE17 NOISO A--SSY--RSSGLSGMERRRTPSPQFSPQRLSDKPPVPFPQEDSD--------------- OTOGAGS_2886_PE1 NOISO PP-PQTQQNT----AME--SRSYTQFAPXXXXXRPPLLMQDEESTR-------------- PANTRX_11_PE1 NOISO VP-PKQQHLRLQTATMETSRSPSPQFAPQKLTDRPPLLIQDEDSTR-------------- PIGX_6_PE3 NOISO VE-LGVA--HLDTCCVHAAREPRPLNQPEKLRTQVPGMRGCENSKL-------------- POEGU1_20_PE6 NOISO --SSKY--RYLQKPGMESSRSPSPQFAPQKLTDKPPVSLQDENPA--------------- PONPYX_10_PE2 NOISO LP-PKQQHLRLQTATMETSRSPSPQFAPQKLTDKPPLLIQDEDSTR-------------- PTEVAGS_2083_PE1 NOISO LP-SKVR--PPATSAMETSRSPSPQFAPQKLTDKPPLLIQDESSTR-------------- RATX_PE414 ENSRNOG00000024322 LS-SKCQ--HLQTSTMETSRSPSPQFAPQKLTDKPPLLIHEDNSAR-------------- RATX_PE415 ISOFORMIN LS-SKCQ--HLQTSTMETSRSPSPQFAPQKLTDKPPLLIHEDNSARYCPVTACYVFIPC- SPETRGS_3166_PE1 NOISO XX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------------- TARSYGS_4663_PE1 NOISO LP-PKHRHLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-------------- TETNG3_PE72 ENSTNIG00000017158 ----------------DRARTPSPPFGRQRLRDTAAAALLQDDSPPRLAAASASPVKPGG TETNG3_PE73 ISOFORMIN ----------------DRARTPSPPFGRQRLRDTAAAALLQDDSPPRLAAASASPVKPGG TURTRGS_550_PE3 NOISO LLSK-F--RPLQTSAMETSRSPSPQFAPQKLTDKPPLLVQDDNST--------------- MATCH CONSENSUS ???????????????M???RSPSPQF?PQ?L?D?PP????????????????????????

AILMEGL194998_1_PE1 NOISO ------------------------------IERVMDNNT-TVKMVPIKIVHSESQPEKES ANOCA81_2_PE4 NOISO -----------------------------RIERVMDNNT-TVKMVPIKIVHSESHAEKES BOVINX_88_PE9 NOISO ------------------------------IERVMDNNT-TVKMVPIKIVHSESQPEKES CALJAX_9_PE1 ENSCJAG00000000928 ------------------------------IERVIDNNT-TVKMVPIKIVHSESQPEKES CALJAX_9_PE2 ISOFORMIN ------------------------------IERVIDNNT-TVKMVPIKIVHSESQPEKES CANFAX_7_PE3 NOISO ------------------------------IERVIDNNT-TVKMVPIKIVHSESQPEKES CAVPO126_2_PE3 NOISO ------------------------------IERVIDNNT-TVKMVPIKIVHSESQPEKES CHICK1_PE2106 NOISO -----------------------------RIERVIDNNT-TVKMVPIKIVHSESSAEKES DANRE11_47_PE9 NOISO ------------------------------SSKVEEPNT-PGRKVPIQIVCTENGSERDI DANRE6_32_PE4 NOISO ---------------------------PGRMDQIKDENT-SVKKVPIKIVHSESDTEKES ECHTEGS_4788_PE1 NOISO ------------------------------IERVMDNNT-TVKMVPIKIVHSESQPEKES FELCAGS_2696_PE1 NOISO ------------------------------XXXXXXXXX-XXXXXXXXXXXXXXXXXXXX FUGRU13_1_PE137 ISOFORMIN -----------------------------RMTHVTETQTSAAKRVPIRIVHSEGVTEKES FUGRU13_1_PE138 ISOFORMIN -----------------------------RMTHVTETQTSAAKRVPIRIVHSEGVTEKES FUGRU13_1_PE139 ENSTRUG00000012349 -----------------------------RMTHVTETQTSAAKRVPIRIVHSEGVTEKES FUGRU13_1_PE140 ISOFORMIN ---------------INKLVDQIFCLSYFRMTHVTETQTSAAKRVPIRIVHSEGVTEKES FUGRU57_1_PE17 NOISO --------IVRMLSLHHRHEYCSLSENDLKLPAEMDVIS-AVRKVPVMIPHSDSSSE--Y GASACGROUPI_29_PE25 NOISO ---S----RQQKDVVRSKGGAVKMSEKDVKLPAEMEPMS-PGRKAPVSGIHSESGCRGEG GASACGROUPVIII_19_PE38 NOISO -----------------------------RTEHVVEKPHSAARKVPIRIVHSEVAADKEA GORGOX_11_PE1 NOISO ------------------------------IERVMDNNT-TVKMVPIKIVHSESQPEKES HORSEX_7_PE4 ISOFORMIN ------------------------------IERVIDNNT-TVKMVPIKIVHSESQPEKES HORSEX_7_PE5 ENSECAG00000012150 ------------------------------IERVIDNNT-TVKMVPIKIVHSESQPEKES HSX_PE143 ENSG00000146950 ------------------------------IERVMDNNT-TVKMVPIKIVHSESQPEKES LOXAF94_6_PE2 NOISO ------------------------------IERLMENNT-TVKMVPIKIVHSESQPEKES MACEUGS_5635_PE1 NOISO -----------------------------RIERVIDNNT-TVKMVPIKIVHSESHAEKES MACMUX_8_PE9 ENSMMUG00000006193 ------------------------------IERVMDNNT-TVKMVPIKIVHSESQPEKES MICMUGS_799_PE3 NOISO ------------------------------IERVMDNNT-TVKMVPIKIVHSESQPERES MONDO7_34_PE7 ENSMODG00000017449 -----------------------------RIEKVIDNNT-TVKMVPIKIVHSESHAEKES MONDO7_34_PE8 ISOFORMIN ------------CHFTISIITSVFLLPSLLIEKVIDNNT-TVKMVPIKIVHSESHAEKES MOUSEX_PE1950 ISOFORMIN ------------------------------IERVMDNNT-TVKMVPIKIVHSESQPEKES MOUSEX_PE1951 ENSMUSG00000045180 ------------------------------IERVMDNNT-TVKMVPIKIVHSESQPEKES MYOLUGS_3236_PE1 NOISO -----------------------------------------SKMVPIKIVHSESQPER-- ORNANULTRA462_6_PE4 ENSOANG00000009689 -----------------------------RIERVMENNT-TVKMVPIKIVHSESHAEKES ORNANULTRA462_6_PE5 ISOFORMIN -----------------------------RIERVMENNT-TVKMVPIKIVHSESHAEKES ORYLA2_17_PE12 NOISO FLVIL---FQITRQMELYSLGC-RWDKESRFPAAMEANS-LVRKVPVRIIRSENGAGGSV ORYLA4_32_PE17 NOISO -----------------------------RSVPVIQNQSSAARRVPIRIVHSEGTAEKEH OTOGAGS_2886_PE1 NOISO ------------------------------IERVMDSNT-TVKMVPIRIVHSETQPERES PANTRX_11_PE1 NOISO ------------------------------IERVMDNNT-TVKMVPIKIVHSESQPEKES PIGX_6_PE3 NOISO ------------------------------LQRGM---E-TVKDAPSPSASREATVERRT POEGU1_20_PE6 NOISO -----------------------------RIERVIDNNT-TVKMVPIKIVHSESSAEKES PONPYX_10_PE2 NOISO ------------------------------IERVMDNNT-TVKMVPIKIVHSESQPEKES PTEVAGS_2083_PE1 NOISO ------------------------------IERVIDSNT-TVKMVPIKIVHSESQPEKES RATX_PE414 ENSRNOG00000024322 ------------------------------IERVMDNNT-TVKMVPIKIVHSESQPEKES RATX_PE415 ISOFORMIN -------------RLQVFVAGALPQLQTLGIERVMDNNT-TVKMVPIKIVHSESQPEKES SPETRGS_3166_PE1 NOISO ------------------------------IERVMDNNT-TVKMVPIKIVHSESQPEKES TARSYGS_4663_PE1 NOISO ------------------------------IERVMDNNT-TVKMVPIKIVHSESQPEKES TETNG3_PE72 ENSTNIG00000017158 FERPRDARQKTANCLK-------------------------------------------- TETNG3_PE73 ISOFORMIN FERPRRKNYSSSSCLRRSTENCKLLE----------------------------IGG--F TURTRGS_550_PE3 NOISO -----------------------------RIERVMDNNT-TVKMVPIKIVHSESQPEKES MATCH CONSENSUS ??????????????????????????????????????????K?VPI?IVHSE???E?E?

AILMEGL194998_1_PE1 NOISO RQGLSRTAEL-P---ALPSGLEKDQIKTLSTSEQSYS-RFCL-YSRQGAE---------- ANOCA81_2_PE4 NOISO RQNLVSTIEP-P---ALPSGLEKDQIKTLSTSEQSYS-RFCA-YTRQGVE-PEPENKTRL BOVINX_88_PE9 NOISO RQALARVPEP-P---PLPRGLERDQIKTLSTSEQSYS-RFCP-YSRQGAE---------- CALJAX_9_PE1 ENSCJAG00000000928 RQSLARPTEP-P---ALPRGLEKDQIKTLSTSEQFYS-RFCL-YTRQGTE-PEAPHRAQP CALJAX_9_PE2 ISOFORMIN RQSLARPTEP-P---ALPRGLEKDQIKTLSTSEQFYS-RFCL-YTRQGTE-PEAPHRAQP CANFAX_7_PE3 NOISO RQGLARTAEL-P---ALPSGLERDQIKTLSTSEQSYS-RFCV-YSRQGAE---------- CAVPO126_2_PE3 NOISO RQSLVRLAEL-P---ALPRGLERDQIKTLSTSEQSYS-RFCV-YTRQQPP---------- CHICK1_PE2106 NOISO RQSLVSTMEP-P---ALPSGLEKDQIKTLSTSEQSYS-RFCA-YTRQGVE-PEPETKTKP DANRE11_47_PE9 NOISO RNYLLHSESS--------EEPQTDQLKTLESSEQCHS-PFIA-YSNQIEE-PILDPT--- DANRE6_32_PE4 NOISO RQYLDLPSET-P---VNSQGLVGAHLQSLGNPDQSYS-LFCT-YTRQKDQ-VPGL---RD ECHTEGS_4788_PE1 NOISO RQGLARPTEP-P---ALPTGLGRDQIKTLSSG-QLYS-RFCV-YTRQGAE---------- FELCAGS_2696_PE1 NOISO XXXXXXXXXX-X---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---------- FUGRU13_1_PE137 ISOFORMIN CPFLQPSEPP-A---VEPEGLGVTKFSSLGAAG-QDS-GFCV-FTRQKED-DGAPCSQTD FUGRU13_1_PE138 ISOFORMIN CPFLQPSEPP-A---VEPEGLGVTKFSSLGAAG-QDS-GFCV-FTRQKED-DGAPCSQTD FUGRU13_1_PE139 ENSTRUG00000012349 CPFLQPSEPP-A---VEPEGLGVTKFSSLGAAG-QDS-GFCV-FTRQKED-DGAPCSQTD FUGRU13_1_PE140 ISOFORMIN CPFLQPSEPP-A---VEPEGLGVTKFSSLGAAG-QDS-GFCV-FTRQKED-DGAPCSQTD FUGRU57_1_PE17 NOISO ETQLP--QGRES---CGGS--------PLP----P-----CV--SS--VS---------- GASACGROUPI_29_PE25 NOISO RACLP--RSGET---CVPV--------QAP----PPGARTCQ--DPAQAS---------- GASACGROUPVIII_19_PE38 NOISO CPYLQHGDAPHA---VEAEGPGVIRLVGRGAAG-QDS-GFCA-FTRQGET---------- GORGOX_11_PE1 NOISO RQSLACPAEP-P---ALPHGLEKDQIKTLSTSEQFYS-RFCL-YTXXXXXXXXXXXRAQP HORSEX_7_PE4 ISOFORMIN RQGLARATEL-P---ELPSGLERDQIKTLSTSEQCYS-RFCV-YSRQGPE---------- HORSEX_7_PE5 ENSECAG00000012150 RQGLARATEL-P---ELPSGLERDQIKTLSTSEQCYS-RFCV-YSRQGPE---------- HSX_PE143 ENSG00000146950 RQSLACPAEP-P---ALPHGLEKDQIKTLSTSEQFYS-RFCL-YTRQGAE-PEAPHRAQP LOXAF94_6_PE2 NOISO RQGLAQPAEP-P---TLPSGLERDQIKTLSTSEQSYS-RFCV-YTRQGAE-SGEPPRARP MACEUGS_5635_PE1 NOISO RQNLVSTMEP-P---ALPSGLEKDQIKTLSTSEQSYS-RFCA-YTRQGVE-PEAENKARV MACMUX_8_PE9 ENSMMUG00000006193 RQSLARPAEP-P---ALPRGLEKDQIKTLSTSEQFYS-RFCL-YTRQGAE-PEAPHRAQP MICMUGS_799_PE3 NOISO RQSLARPAEL-PALPALPSGLEKDQIKTLSTSEQFYS-RFCV-YTRQGAE---------- MONDO7_34_PE7 ENSMODG00000017449 RQNLVSTMEP-P---ALPSGLEKDQIKTLSTSEQSYS-RFCA-YTRQGVE-PEAENKTRA MONDO7_34_PE8 ISOFORMIN RQNLVSTMEP-P---ALPSGLEKDQIKTLSTSEQSYS-RFCA-YTRQGVE-PEAENKTRA MOUSEX_PE1950 ISOFORMIN RQSLACPAEL-P---PLPSGLERDQIKTLSTSEQCYS-RFCV-YTRQEVE---APHRARP MOUSEX_PE1951 ENSMUSG00000045180 RQSLACPAEL-P---PLPSGLERDQIKTLSTSEQCYS-RFCV-YTRQEVE---APHRARP MYOLUGS_3236_PE1 NOISO ------------------------------------------------------------ ORNANULTRA462_6_PE4 ENSOANG00000009689 RQSLVSPLEL-P---ALPCGLEKDQIKTLSTSEQSYS-RFCA-YTRQGAE-PEAPSKTRL ORNANULTRA462_6_PE5 ISOFORMIN RQSLVSPLEL-P---ALPCGLEKDQIKTLSTSEQSYS-RFCA-YTRQGAE-PEAPSKTRL ORYLA2_17_PE12 NOISO GSLSHAPLSDAT---VN-S--------DAS----L---FSAV--ARQAAG---------- ORYLA4_32_PE17 NOISO SPFLQQSELV-H---VEAGGPGAGRVGSFGALA-EDS-DFCA-FSRHCNK---TPETQVQ OTOGAGS_2886_PE1 NOISO RQSLACPAEL-P---ALPSGLQKDQIKTLSTSEQCYS-RFCV-YTRQGAPG--------- PANTRX_11_PE1 NOISO RQSLACPAEP-P---ALPHGLEKDQIKTLSTSEQFYS-RFCL-YTRQGAE-PEAPHRAQP PIGX_6_PE3 NOISO VSTAKCVVCF-P---NFDGGLSLDFLGRLGTPYLCQS-KACA-HTRTSSA-MHRPSASKP POEGU1_20_PE6 NOISO RQSLVSTMEP-P---ALPSGLEKDQIKTLSTSEQSYS-RFCA-YTRQGVE-PEPEARTKP PONPYX_10_PE2 NOISO RQSLACPTEP-P---ALPHGLEKDQIKTLSTSEQFYS-RFCL-YTRQGAE-PEAPLRAQP PTEVAGS_2083_PE1 NOISO RQGLACAAEL-P---ALPSGLERDQIKTLSTSEQSYS-RFCV-YSRPGAE---------- RATX_PE414 ENSRNOG00000024322 RQSLACPAEL-P---ALPSGLEKDQIKTLSTSEQCYS-RFCV-YTRQEVE---TPHRARP RATX_PE415 ISOFORMIN RQSLACPAEL-P---ALPSGLEKDQIKTLSTSEQCYS-RFCV-YTRQEVE---TPHRARP SPETRGS_3166_PE1 NOISO RQSLARPAEL-P---VLPSGLERDQIKTLSTSEQCYS-RFCV-YTRHGAE-TEAPHKAHS TARSYGS_4663_PE1 NOISO RQSLARPAEL-P---ALPSGLEKDQIKTLSTSEQSYS-RFCV-YTRQGAE-PEAQHRARP TETNG3_PE72 ENSTNIG00000017158 ----------------------------------------CK--S--------------- TETNG3_PE73 ISOFORMIN YCEAK--SGRCR---CCGR---------------------CR--SV-------------- TURTRGS_550_PE3 NOISO RQGLARVPEP-P---MLPSGLERDQIKTLSTSEQSYS-RFCL-YSRQGAE-PQPPGT--- MATCH CONSENSUS ???L???????????????G????????L???????S??FC????R??????????????

AILMEGL194998_1_PE1 NOISO PEPQRPSAPAPRANDHGA---------SPSALSYVKA--------KERTAEDL-KSEELA ANOCA81_2_PE4 NOISO PYLQPAEALGPPTKDTDV---------SGHTVSYVRA--------KEKTIEDW-KSEELA BOVINX_88_PE9 NOISO PQP-ATGALGPPAKEGRA---------SPPVLSYVKA--------KDRTADDL-KSEELA CALJAX_9_PE1 ENSCJAG00000000928 AQPQPSSTQEPPEKDRCA---------SPPGLSYMKA--------KEKTEEDL-KSEELA CALJAX_9_PE2 ISOFORMIN AQPQPSSTQEPPEKDRCA---------SPPGLSYMKA--------KEKTEEDL-KSEELA CANFAX_7_PE3 NOISO PEPQPPSTPAPPTKDSGA---------SPSGLSYVKA--------KERTAEDL-KSEELA CAVPO126_2_PE3 NOISO V-PQSSVPPMAPASDVC----------ASPPFSYAKT--------KEKTAEDL-KSEELA CHICK1_PE2106 NOISO TDPQPAEEPGNNLKDSSA---------AVPVVSYVKA--------KEKTLEDW-KSEELA DANRE11_47_PE9 NOISO ------EPMRSN-------------------------------GVSEHSEDDL-KREELA DANRE6_32_PE4 NOISO PDMGPLKDQGPQ-----S---------NINPVSYVEPGLQTGPPLDQSTNEDD-KRKELA ECHTEGS_4788_PE1 NOISO P--GEPSRSQPPAPESRA---------SPAGLGYGKG--------REKTEEDL-KSEELA FELCAGS_2696_PE1 NOISO XXXXXXXXXXXXXXXXXX---------XXXXXXXXXX--------XXXXXXXXXXXXXXX FUGRU13_1_PE137 ISOFORMIN TKPQRLTYLSPIRDHISSSFQNPPQSSDESRSDEAVA--------PTQLSEDQ-KREELA FUGRU13_1_PE138 ISOFORMIN TKPQRLTYLSPIRDHISSSFQNPPQSSDESRSDEAVA--------PTQLSEDQ-KREELA FUGRU13_1_PE139 ENSTRUG00000012349 TKPQRLTYLSPIRDHISSSFQNPPQSSDESRSDEAVA--------PTQLSEDQ-KREELA FUGRU13_1_PE140 ISOFORMIN TKPQRLTYLSPIRDHISSSFQNPPQSSDESRSDEAVA--------PTQLSEDQ-KREELA FUGRU57_1_PE17 NOISO -------AT-------------------------EHPS---NSAGPLQSLEDA-KREELA GASACGROUPI_29_PE25 NOISO -------AT-------------------------VQGA---GPPGDRGSEEDA-KREELA GASACGROUPVIII_19_PE38 NOISO --AQADAYMTTVGDHGLSDGPPPAHAE----VTEVTE--------VTRLSEDQ-KRDELA GORGOX_11_PE1 NOISO AEPQPLGTQVPPEKDRCA---------SPPGLSYVKA--------KEKTVEDL-KSEELA HORSEX_7_PE4 ISOFORMIN AEPQPPGALAPAAKDSQA---------SPPGLSYVKA--------KERTAEDL-KSEELA HORSEX_7_PE5 ENSECAG00000012150 AEPQPPGALAPAAKDSQA---------SPPGLSYVKA--------KERTAEDL-KSEELA HSX_PE143 ENSG00000146950 AEPQPLGTQVPPEKDRCT---------SPPGLSYMKA--------KEKTVEDL-KSEELA LOXAF94_6_PE2 NOISO TEPEPPGAQVPPTKESCA---------SPGGLSYMKA--------KEKTAEDL-KSEELA MACEUGS_5635_PE1 NOISO SDSEPAEALGYNLKDSDA---------SIPVVSYMKA--------KEKTLEDL-KSEELA MACMUX_8_PE9 ENSMMUG00000006193 AEPQPLGTQAPPEKDRCA---------SPPGLSYMKA--------KEKTVEDL-KSEELA MICMUGS_799_PE3 NOISO --PEPPGARAPPEKDGCA---------SPPGLSYVKA--------KEKTVEDL-KSEELA MONDO7_34_PE7 ENSMODG00000017449 ADSEAAEALGYNLKDGEE---------SSPAVSYMKA--------KEKTLEDL-KSEELA MONDO7_34_PE8 ISOFORMIN ADSEAAEALGYNLKDGEE---------SSPAVSYMKA--------KEKTLEDL-KSEELA MOUSEX_PE1950 ISOFORMIN PEPRPPSTPAPPVRDSCS---------SPPSLNYGKA--------KEKTMDDL-KSEELA MOUSEX_PE1951 ENSMUSG00000045180 PEPRPPSTPAPPVRDSCS---------SPPSLNYGKA--------KEKTMDDL-KSEELA MYOLUGS_3236_PE1 NOISO ------------------------------------------------------------ ORNANULTRA462_6_PE4 ENSOANG00000009689 ADSQPAEALAPNMKDGEA---------STPTVSYVKA--------KEKTFEDL-KSEELA ORNANULTRA462_6_PE5 ISOFORMIN ADSQPAEALAPNMKDGEA---------STPTVSYVKA--------KEKTFEDL-KSEELA ORYLA2_17_PE12 NOISO -------DP-------------------------EQPSNQEGRPAGPVEEEDA-KREELA ORYLA4_32_PE17 NOISO QRPETDGYMTTIGDDVQLPPPPPMV-------AYMMT--------IGDDVEEQ-KREELA OTOGAGS_2886_PE1 NOISO -----APAQAPLEKDGCA---------SPPGLGYVKA--------KEKIVEDL-KSEELV PANTRX_11_PE1 NOISO AEPQPLGTQVPPEKDRCA---------SPPGLSYMKA--------KEKTVEDL-KSEELA PIGX_6_PE3 NOISO PRPFSPMKPIPTVLNTCV---------SPPNLETGRA--------LEGRMSAQ-RSGKLW POEGU1_20_PE6 NOISO VDPQPAEEPGSNLKDSSV---------ATQASSYVKA--------KEKTFEDW-KSEELA PONPYX_10_PE2 NOISO AEPQPLDTQVPPEKDRCA---------SPPGLSYMKA--------KEKTVEDL-KSEELA PTEVAGS_2083_PE1 NOISO --PQPQPPAAPAASDGRA---------SPPALSYVKA--------RERTAEDL-KSEELA RATX_PE414 ENSRNOG00000024322 PEPQPPSTPAPPVRDSCS---------SPPSLNYGKA--------KEKTVDDL-KSEELA RATX_PE415 ISOFORMIN PEPQPPSTPAPPVRDSCS---------SPPSLNYGKA--------KEKTVDDL-KSEELA SPETRGS_3166_PE1 NOISO LEPQPSSTPIPPVKNVCA---------SPPGLSYMKT--------KEKTMEDL-KSEELA TARSYGS_4663_PE1 NOISO AEPEPPSAQAPPEKERCA---------SPPGLSYIKA--------KEKTVEDL-KSEELA TETNG3_PE72 ENSTNIG00000017158 --------------------------------------------------------VLKR TETNG3_PE73 ISOFORMIN ----------------------------------E------AVVGVM--------RLLIW TURTRGS_550_PE3 NOISO --------PVPTAKDSRA---------STPTLSYVKA--------KERTAEDL-KSEELA MATCH CONSENSUS ???????????????????????????????????????????????????D??K?EELA

AILMEGL194998_1_PE1 NOISO REI-VGKDKSLA-DILDPS-VKIRTT-MDLME-GIFPKDEH-LLEEAQQRRKLLPKVPS- ANOCA81_2_PE4 NOISO REI-VGKDKSLA-DILDPN-MKIKTT-MDLMV-GIFPKDEH-LLEEAQQRRKLLLKVPS- BOVINX_88_PE9 NOISO REI-AGRDKSLA-DILDPG-VRMRTT-MDLME-GIFPKDEH-LLEGAQQRRKLLPKGPS- CALJAX_9_PE1 ENSCJAG00000000928 REI-VGKDKSLA-DILDPS-VKIKTT-MDLME-GIFPKDEH-LLEEAQQRRKLLPKIPS- CALJAX_9_PE2 ISOFORMIN REI-VGKDKSLA-DILDPS-VKIKTT-MDLME-GIFPKDEH-LLEEAQQRRKLLPKIPS- CANFAX_7_PE3 NOISO REI-VGKDKSLA-DILDPS-VKIRTT-MDLME-GIFPKDEH-LLEEAQQRRKLLPKIPS- CAVPO126_2_PE3 NOISO REI-VGKDKSLA-DILDPS-MKIKTT-MDLME-GIFPKDEH-LLEEAQQRRKLLPKIPS- CHICK1_PE2106 NOISO REI-VGRDKSLA-DILDPN-VKIKTA-MDLMV-GIFPKDEH-LLEEAQQRRKLLPKVPS- DANRE11_47_PE9 NOISO RDI-MGKDRSLV-DILDQ--RKMKTT-MDLME-GIFPQGEQ-ILEGAQQRRKAASKQTS- DANRE6_32_PE4 NOISO RDI-MDKDKSLA-DILDQ--SKMKTT-MDLME-GIFPQGDQ-LLEEAQQRRKAQPKPLS- ECHTEGS_4788_PE1 NOISO REI-VGKDRSLA-DVLDPS-VKMKTT-MDLMG-GIFPKAEL-LLEEAQQRRKLHPKAPS- FELCAGS_2696_PE1 NOISO XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX- FUGRU13_1_PE137 ISOFORMIN KDI-MGKDKSLA-DILDQ--SKMKTT-MDLME-GIFPPEEQ-LLEGAHQRRKVLPKQTV- FUGRU13_1_PE138 ISOFORMIN KDI-MGKDKSLA-DILDQ--SKMKTT-MDLME-GIFPPEEQ-LLEGAHQRRKVLPKQTV- FUGRU13_1_PE139 ENSTRUG00000012349 KDI-MGKDKSLA-DILDQ--SKMKTT-MDLME-GIFPPEEQ-LLEGAHQRRKVLPKQTV- FUGRU13_1_PE140 ISOFORMIN KDI-MGKDKSLA-DILDQ--SKMKTT-MDLME-GIFPPEEQ-LLEGAHQRRKVLPKQTV- FUGRU57_1_PE17 NOISO RDI-MGKDRTLV-DILDQ--SGRMTT-MDLME-GIFPMEDQ-LLEGVFQRRRASVGSRLP GASACGROUPI_29_PE25 NOISO RDI-IRKDKSLV-DILDQ--SGRMTT-MDLME-GLFPTEEQ-VLEGAHLRRRASSGSRLP GASACGROUPVIII_19_PE38 NOISO RSI-MGKDKSLT-EILDQ--SKMKTT-MDLME-GIFPQEEQ-LLEGAHQRRKVN------ GORGOX_11_PE1 NOISO REI-VGKDKSLA-DILDPS-VKIKTT-MDLME-GIFPKDEH-LLEEAQQRRKLLPKIPS- HORSEX_7_PE4 ISOFORMIN REI-VGKDKSLA-DILDPG-VKIKTA-MDLME-GIFPKDEH-LLEEAQQRRKLLPKIPS- HORSEX_7_PE5 ENSECAG00000012150 REI-VGKDKSLA-DILDPG-VKIKTA-MDLME-GIFPKDEH-LLEEAQQRRKLLPKIPS- HSX_PE143 ENSG00000146950 REI-VGKDKSLA-DILDPS-VKIKTT-MDLME-GIFPKDEH-LLEEAQQRRKLLPKIPS- LOXAF94_6_PE2 NOISO REI-VGKDRSLA-DVLDPS-VKMKTT-MDLMG-G