Alignment of the gene Family HOG000012381 of HOGENOM

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Threshold: 50% 80% 100%
Size: Bigger Smaller Normal
Isoforms are ON
AILMEGL193473_1_PE1 NOISO SNQYQEEGCSERPECK-SKSPTLLSSYCIDSILGRRSPCKMRLLGARAGRLAGHLHRAAR ANOCA775_PE2 NOISO ------------------------------------------------------------ BOVINX_74_PE2 NOISO SNQYQEEGCSERPECK-SKSPTLLSSYCIDSILGRRSPCKMRLLGAAQSLPAPLASRTDQ CALJAX_25_PE2 NOISO SNQYQEEGCSERPECK-SKSPTLLSSYCIDSILGRRSPCKMRLLGAAQSLPAPLTSRADQ CANFAX_21_PE7 NOISO SNQYQEEGCSERPECK-SKSPTLLSSYCIDSILGRRSPCKMRLLGAAQSLPAPLASRADQ DANRE24_26_PE20 ENSDARG00000058011 SSQYDDDSR-DRSECK-SKSPTVLSSYCIDSILGRRSPCKVRQLGA-QSLPA-PV-RP-- DANRE24_26_PE21 ISOFORMIN SSQYDDDSR-DRSECK-SKSPTVLSSYCIDSILGRRSPCKVRQLGA-QSLPA-PV-RP-- DANREZV9_3460_PE2 NOISO SSEVEEDNP-EQTNCR-CKTPTLLSSYCIDSILGRKSPLKVQEYIV-HGKSK-LMLKNST FUGRU152_PE63 ENSTRUG00000007885 SGQFEDDIC-DRSERKSSKSPTLLSSYCIDSILGRRSPCKVRLIGT-QSLTG-LPGRGEL FUGRU152_PE64 ISOFORMIN SGQFEDDIC-DRSERKSSKSPTLLSSYCIDSILGRRSPCKVRLIGT-QSLTG-LPGRGEL GORGOX_27_PE4 ENSGGOG00000023361 SNQYQEEGCSERPECK-SKSPTLLSSYCIDSILGRRSPCKMRLLGAAQSLPAPLTSRADP GORGOX_27_PE5 ISOFORMIN SNQYQEEGCSERPECK-SKSPTLLSSYCIDSILGRRSPCKMRLLGAAQSLPAPLTSRADP HORSEX_20_PE4 NOISO ------------------------------------------------------------ HSX_PE449 NOISO SNQYQEEGCSERPECK-SKSPTLLSSYCIDSILGRRSPCKMRLLGAAQSLPAPLTSRADP LOXAF39_7_PE1 ISOFORMIN SNQYQDEGCSERPECK-SKSPTLLSSYCIDSILGRRSPCKMRLLGAAQSLPAPLASRADQ LOXAF39_7_PE2 ENSLAFG00000001779 SNQYQDEGCSERPECK-SKSPTLLSSYCIDSILGRRSPCKMRLLGAAQSLPAPLASRADQ LOXAF39_7_PE3 ISOFORMIN ------------------------------------------------------------ MACEUGS_1794_PE2 NOISO SSQYQEESCSERPECK-SKSPTLLSSYCIDSILGRRSPCKMRLLGAAQSLPS-LSNRADQ MACMUX_24_PE5 NOISO SNQYQEEGCSERPECK-SKSPTLLSSYCIDSILGRRSPCKMRLLGAAQSLPAPLTSRADP MONDO4_41_PE1 NOISO SNQYQEESCSERPECK-SKSPTLLSSYCIDSILGRRSPCKMRLLGAAQSLPS-LSNRTDQ MOUSEX_PE1159 ENSMUSG00000035277 SNQYQEEGCSERPECK-SKSPTLLSSYCIDSILGRRSPCKMRLLGAAQSLPAPLASRADQ MOUSEX_PE1160 ISOFORMIN SNQYQEEGCSERPECK-SKSPTLLSSYCIDSILGRRSPCKMRLLGAAQSLPAPLASRADQ ORYLA20_14_PE18 NOISO SGQFEDDIH-ERGERKSSKSPTLLSSYCIDSILGRRSPCKVRLIGA-QTLTA-LPCRGEL POEGU1_13_PE1 NOISO SGPYPEESCAERPECK-SKSPTLLSSYCIDSILGRRSPCKVRLLGTAPTLPA-IAARPDT PONPYX_26_PE7 NOISO SNQYQEEGCSERPECK-SKSPTLLSSYCIDSILGRRSPCKMRLLGAAQSLPAPLTSRADP RABITX_12_PE2 NOISO SNQYQEEGCSERPECK-SKSPTLLSSYCIDSILGRRSPCKMRLLGAAQSLPAPLASRADQ RATX_PE669 ENSRNOG00000032074 SNQYQEEGCSERPECK-SKSPTLLSSYCIDSILGRRSPCKMRLLGAAQSLPAPLASRTDQ RATX_PE670 ISOFORMIN SNQYQEEGCSERPECK-SKSPTLLSSYCIDSILGRRSPCKMRLLGAAQSLPAPLASRTDQ SORARGS_26_PE1 NOISO ------------------------------------------------------------ SPETRGS_987_PE2 NOISO SNQYQEEGCSERPECK-SKSPTLLSSYCIDSILGRRSPCKMRLLGAAQSLPAPLASRADQ TARSYGS_29_PE1 NOISO SNQYQEEGCSERPECK-SKSPTLLSSYCIDSILGRRSPCKMRLLGAAQSLPAPLASRADQ TETNG6_PE76 NOISO SGQFEDETR-DRGESKSSKSPTLLSSYCIDSILGRRSPCKVRLVGP-QSLTA-LPGRGEP TUPGBGS_380_PE4 NOISO SNQYQEEGCSERPECK-SKSPTLLSSYCIDSILGRRSPCKMRLLGAAQSLPAPLASRADQ XENTR64_2_PE6 NOISO SSHYPEE-TSERPECK-SKSPTLLSSYCIDSILGRRSPCKMRLLGA-QSLPS-LAHRLDP MATCH CONSENSUS S??????????R?E?K?SKSPTLLSSYCIDSILGRRSPCK?R??G????L??????R???

AILMEGL193473_1_PE1 NOISO ----------------------------------TRKRPWGQGPGVIKLEMEERERTTLR ANOCA775_PE2 NOISO ------------------------------------------------------------ BOVINX_74_PE2 NOISO EKAVQGKAVL-----------AEH---L--------KRVLGTGLDTIFLGEEPPPLLVGA CALJAX_25_PE2 NOISO EKAVQGSPKSSGAPFEAELHLPPK---L--------RRLYGPGGGRLLQGGPRG------ CANFAX_21_PE7 NOISO EKAVQGNRKSQKSGERGEGGPRPG---A--------RGRRGPGPGARAAGRRADRSP--- DANRE24_26_PE20 ENSDARG00000058011 DHEMTTEVTSKENSFDSDMHLPPK---L--------RRLYGPGGKYLDSGRGFHEHLE-- DANRE24_26_PE21 ISOFORMIN DHEMTTEVTSKENSFDSDMHLPPK---L--------RRLYGPGGKYLDSGRGFHEHLE-- DANREZV9_3460_PE2 NOISO GKCLDSETPHSLWPLHPHMHLPPK---L--------RRPFAPLTDSSTDE---------- FUGRU152_PE63 ENSTRUG00000007885 EKTAEISEPTKDFCLTSDMHLPPK---L--------RRLYGPGGKYLHDH------KE-- FUGRU152_PE64 ISOFORMIN EKTAE-TKPTKDFCLTSDMHLPPK---L--------RRLYGPGGKYLHDH------KE-- GORGOX_27_PE4 ENSGGOG00000023361 EKAVQGSPKSSSAPFEAELHLPPK---L--------RRLYGPGGGRLLQGAAAAAXXXX- GORGOX_27_PE5 ISOFORMIN EKAVQGSPKSSSAPFEAELHLPPK---L--------RRLYGPGGGRLLQGAAAAAX---- HORSEX_20_PE4 NOISO ------------------------------------------------------------ HSX_PE449 NOISO EKAVQGSPKSSSAPFEAELHLPPK---L--------RRLYGPGGGRLLQGAAAAAAAAA- LOXAF39_7_PE1 ISOFORMIN EKAVQGKAAPASNLRRAPGIVCWGRRKKRGQ---PRGLVLP-R--AIII----------- LOXAF39_7_PE2 ENSLAFG00000001779 EKAVQGKAAPASNLRRAPGIV-WGRLSLSASKQQRPGFAFGPLGFAVLVVGRLN------ LOXAF39_7_PE3 ISOFORMIN ------------------------------------------------------------ MACEUGS_1794_PE2 NOISO DKVAQGSPKGSSPQFEAELHLPPK---L--------RRLYGPGGGRLLQGAAAAAAAAAA MACMUX_24_PE5 NOISO EKAVQGSPKSSSAPFEAELHLPPK---L--------RRLYGPGGGRLLQGAAAAAAAAA- MONDO4_41_PE1 NOISO DKVAQGSPKGSSPQFEAELHLPPK---L--------RRLYGPGGGRLLQGAAAAAAAAAA MOUSEX_PE1159 ENSMUSG00000035277 EKAMQGSPKSSSAPFEAELHLPPK---L--------RRLYGPGGGRLLQGAAAAAAAAAA MOUSEX_PE1160 ISOFORMIN EKAMQGSPKSSSAPFEAELHLPPK---L--------RRLYGPGGGRLLQGAAAAAAAAAA ORYLA20_14_PE18 NOISO GKAADGP-TKEPISLSADVHLPPK---L--------RRLYGPGGKYLHDH------AE-- POEGU1_13_PE1 NOISO DKAAQGSPKASPPFEPAELHLPPK---L--------RRLYGPGGGRLLPPRAAGPRGD-- PONPYX_26_PE7 NOISO EKAVQGSPKSSSAPFEAELHLPPK---L--------RRLYGPGGEE-------------- RABITX_12_PE2 NOISO EKAVQGSLDGSNLPFGGFEYAPNR---V--PQIRNKRCPLGPGSKNLMKTRNSKADGH-- RATX_PE669 ENSRNOG00000032074 EKAMQGSPKGSSAPFEAELHLPPK---L--------RRLYGPGGGRLLQGAAAAAAAAAA RATX_PE670 ISOFORMIN EKAMQGSPKGSSAPFEAELHLPPK---L--------RRLYGPGGGRLLQGAAAAAAAAAA SORARGS_26_PE1 NOISO ------------------------------------------------------------ SPETRGS_987_PE2 NOISO EKAVQXXXXGSGAPFGQMLLLPK----L--------GCLMCSGGGRSLLVADAGWSTAAA TARSYGS_29_PE1 NOISO EKAVQAFT---------------------------------------------------- TETNG6_PE76 NOISO EKTAEK--AAKDFPLAADMHLPPK---L--------RRLYGPGGKYLHDH------GD-- TUPGBGS_380_PE4 NOISO EKAVQGSPNGSSAPVGVELHLPPK---L--------RRLYGGGGLLLRDAAAAAAV---- XENTR64_2_PE6 NOISO DKTLEGSPKGN-AAFEADLHLPPK---L--------RRLYGPVGGSGRIHLQAVADAR-- MATCH CONSENSUS ????????????????????????????????????????????????????????????

AILMEGL193473_1_PE1 NOISO PGASKSG---KHLARGCLSLSLGFLKHRP--------SFALAGAGGGCLDFRNWSLNLLN ANOCA775_PE2 NOISO ------------------------------------------------------------ BOVINX_74_PE2 NOISO LG--ARSSLRAT---GPL-PPPREKKKRPLQRAP-ERATLET-CAPERSHSGPL-ALQSR CALJAX_25_PE2 NOISO ----------------EA-PPPPPPTARPGERPD-GAGAAAA----AASAADTL-E-ISQ CANFAX_21_PE7 NOISO -LPAGSP-KGSGAPFEAE-LHKQHPTARPGERPD-GAGAAVPAAAAAAAAWDTL-K-ISQ DANRE24_26_PE20 ENSDARG00000058011 ----------------------------KGER---E-RLL-------D--QACESLKISQ DANRE24_26_PE21 ISOFORMIN ----------------------------KGER---E-RLL-------D--QACESLKISQ DANREZV9_3460_PE2 NOISO ------------------------------TA---GPRLL-------Q--TACEKLKITE FUGRU152_PE63 ENSTRUG00000007885 ----------------------------TLDR---ERLLM-------E--QASESLKISQ FUGRU152_PE64 ISOFORMIN ----------------------------TLDR---ERLLM-------E--QASESLKISQ GORGOX_27_PE4 ENSGGOG00000023361 XXXXXXX-XXXXX---------------XXXXXX-XXXXXXXXXXAAAAAWDTL-K-ISQ GORGOX_27_PE5 ISOFORMIN ---------------------------------------------AAAAAWDTL-K-ISQ HORSEX_20_PE4 NOISO ------------------------------------------------------------ HSX_PE449 NOISO AAAAAAA-TATAGPRGEA-PPPPPPTARPGERPD-GAGAAAAAAAAAAAAWDTL-K-ISQ LOXAF39_7_PE1 ISOFORMIN -------------SPGAVSPSLL-----PSSR---GPASLS--GPLGPPPP--------- LOXAF39_7_PE2 ENSLAFG00000001779 ------------APFGGLGCTLT-----RDDR-----SEIV--GARVDPCSDNLVK---- LOXAF39_7_PE3 ISOFORMIN ------------------------------------------------------------ MACEUGS_1794_PE2 NOISO AAAAAA---A------AA-GPRGEPTARSADRPD-GAGAGAG--VGAASAWDTL-K-ISQ MACMUX_24_PE5 NOISO AAAAAAA-TATAGPRGEA-PPPPPPTARPGERPD-GAGAAAAAAAAAAAAWDTL-K-ISQ MONDO4_41_PE1 NOISO AAAAAAA---ATGPRG------EPQQQRSGDRPD-GAGAGVG----ATSAWDTL-K-ISQ MOUSEX_PE1159 ENSMUSG00000035277 AAAAATA-TGTAGPRGEV-PPPPPPAARPGERQD-SAGAVAA--AAAAAAWDTL-K-ISQ MOUSEX_PE1160 ISOFORMIN AAAAATA-TGTAGPRGEV-PPPPPPAARPGERQD-SAGAVAA--AAAAAAWDTL-K-ISQ ORYLA20_14_PE18 NOISO ----------------------------KLDR---ERLLL-------E--QASESLKISH POEGU1_13_PE1 NOISO ---------------------------RTEGRPEGGA-----GPVPAAAPWDTL-K-ISQ PONPYX_26_PE7 NOISO ------------------------------------------------------------ RABITX_12_PE2 NOISO L--CQALPLKGRGGLCLL-HPHFCPKPRPSQAHVHQDDFSLASCAGSPRPFSLW-A-IGA RATX_PE669 ENSRNOG00000032074 AXPAXTTPXRTXGXRXDX-PXR--PXXXPQXXXX-XXX-XXXXXXXXAAAWDTL-K-ISQ RATX_PE670 ISOFORMIN AXPAX-KXERTXGXRXDX-PXR--PXXXPQXXXX-XXXXXXXXXXXXAAAWDTL-K-ISQ SORARGS_26_PE1 NOISO ------------------------------------------------------------ SPETRGS_987_PE2 NOISO LA--SQGGLASSGSRGET-LLPLSPIARPGERPYG-AAATVLAAAAAAAAWDTL-K-ISQ TARSYGS_29_PE1 NOISO ----------------------------------------------PTAAWDTL-K-ISL TETNG6_PE76 NOISO ----------------------------ALDR---ERLLL-------E--QASESLKISQ TUPGBGS_380_PE4 NOISO -VAVSAAVTATAGPRGEA-PPPPPPTARPGERPD-SAGAAVAAAAAAAAAWDTL-K-ISQ XENTR64_2_PE6 NOISO ----------SGVP-------------R----SEKTDRILLL-GGAGENTWDNHSLKISQ MATCH CONSENSUS ????????????????????????????????????????????????????????????

AILMEGL193473_1_PE1 NOISO APFGGLGGALKRGDRS-----ETAGREEW-----ERDGGGQKKKREGKRKAPPKAA---A ANOCA775_PE2 NOISO ------------------------------------------------------------ BOVINX_74_PE2 NOISO LPARSQARRKQ------RCRPSPPGLKSPLSIAVLSPSAH-IKRSVGLLYA--------G CALJAX_25_PE2 NOISO APHVSISRSKSYRENGAPFLPP-PALDE------LGGPGG-VPHPE-ELCC--------A CANFAX_21_PE7 NOISO APQVSISRSKSYRENGAPFVPPPPALDE------LGGPGG-AAHPD-ERLG--------A DANRE24_26_PE20 ENSDARG00000058011 APQVSISRSKSYRENAPFSQSDEGQSPE-----------H-------------------- DANRE24_26_PE21 ISOFORMIN APQVSISRSKSYRENAPFSQSDEGQSPE-----------H-------------------- DANREZV9_3460_PE2 NOISO ASIVNISRAGSYQEHASCKNTPINEEE--------------------------------- FUGRU152_PE63 ENSTRUG00000007885 APQVSISRSKSYRENASLGRGEGEQSPG-----------E-GSE---------------- FUGRU152_PE64 ISOFORMIN APQVSISRSKSYRENASLGRGEGEQSPG-----------E-GSE---------------- GORGOX_27_PE4 ENSGGOG00000023361 APQVSISRSKSYRENGAPFVPPPPALDE------LGGPGG-VTHPE-ERLG--------V GORGOX_27_PE5 ISOFORMIN APQVSISRSKSYRENGAPFVPPPPALDE------LGGPGG-VTHPE-ERLG--------V HORSEX_20_PE4 NOISO ------------------------------------------------------------ HSX_PE449 NOISO APQVSISRSKSYRENGAPFVPPPPALDE------LGGPGG-VTHPE-ERLG--------V LOXAF39_7_PE1 ISOFORMIN PPQAFPR------AFSLGSSRPLPLRAGW------GEAGAQGHRAASPRRGRPRGSTPLA LOXAF39_7_PE2 ENSLAFG00000001779 TRNPKIE------LSCCSSSRPLPLRAGW------GEAGAQGHRAASPRRGRPRGSTPLA LOXAF39_7_PE3 ISOFORMIN ------------------------------------------------------------ MACEUGS_1794_PE2 NOISO APQVSISRSKSYRENGAPFVPPPPALDE------LGSKGG-APHPD-DRLG--------Q MACMUX_24_PE5 NOISO APQVSISRSKSYRENGAPFVPPPPALDE------LGGPGG-VTHPE-ERLG--------A MONDO4_41_PE1 NOISO APQVSISRSKSYRENGAPFVPPPPALDE------LGSKGG-APHPD-DRLG--------Q MOUSEX_PE1159 ENSMUSG00000035277 APQVSISRSKSYRENGAPFVPPPPALDE------LSGPGG-VAHPE-ERLS--------A MOUSEX_PE1160 ISOFORMIN APQVSISRSKSYRENGAPFVPPPPALDE------LSGPGG-VAHPE-ERLS--------A ORYLA20_14_PE18 NOISO APQVSISRSKSYRENASLSRGEGDQSPG-----------E-VSE---------------- POEGU1_13_PE1 NOISO APQVSISRSKSYRENA-PFVAPPPARDE------LGSPAAHVEERPG------------- PONPYX_26_PE7 NOISO ------------------------------------------------------------ RABITX_12_PE2 NOISO RPAL---WAKGLSPGCTPALPLSPARTR-------GGAAGRGPAAPRERRQ--------- RATX_PE669 ENSRNOG00000032074 APQVSISRSKSYRENGAPFVPPPPALDE------LGGPGG-VAHPE-ERLS--------A RATX_PE670 ISOFORMIN APQVSISRSKSYRENGAPFVPPPPALDE------LGGPGG-VAHPE-ERLS--------A SORARGS_26_PE1 NOISO ---------------EDPYVQPPPPMVE------LASPGG-TTHPD-ERHG--------P SPETRGS_987_PE2 NOISO APQVSISRSKSYRENGAPFVPPPPALDE------LGGPGG-VAHPD-ERLG--------A TARSYGS_29_PE1 NOISO APQVSISRSKSYRENGAPFVPPPPALDE------LGGPGG-VTHPD-ERLG--------A TETNG6_PE76 NOISO APQVSISRSKSYRENASLSRGEGDQSPG-----------E-GSE---------------- TUPGBGS_380_PE4 NOISO APQVSISRSKSYRENGAPFVPPPPALDE------LGGSGG-VAHPD-ERLG--------A XENTR64_2_PE6 NOISO APQVSISRSKSYRENSAPLLREEHSPEGL-----LQQSQQQIQTSATTACT--------S MATCH CONSENSUS ????????????????????????????????????????????????????????????

AILMEGL193473_1_PE1 NOISO PRSRLS-CTCRPSCG-AEDDEEELL-------EDEEDEDEEE-----EL-LEDDEEELL- ANOCA775_PE2 NOISO ------------------------------------------------------------ BOVINX_74_PE2 NOISO LQGQAWTAGSPAGNR-QNSWG--------------EFPPSDW-----C-------LNLG- CALJAX_25_PE2 NOISO LTTPAWCPRSLVGIR-TPEITKKGN-------AARPFESEEK-----SL-LRAREAELR- CANFAX_21_PE7 NOISO ASGPGGAPAAGGGTG-AEDDEEELL-------EDEEDEDEEE-----EL-LEDDEEELL- DANRE24_26_PE20 ENSDARG00000058011 -------------------MAQELVELSTLKFEEDVV-KEEACGDNS-LSPKDEES---L DANRE24_26_PE21 ISOFORMIN -------------------MAQELVELSTLKFEEDVV-KEEACGDNS-LSPKDEES---L DANREZV9_3460_PE2 NOISO --------------------------------------GADICGETNVTLKQ--EREA-- FUGRU152_PE63 ENSTRUG00000007885 ------------------DSSLGLVDLGPLKFEEEAGNKEESCRDAAALSPKDEERESLN FUGRU152_PE64 ISOFORMIN ------------------DSSLGLVDLGPLKFEEEAGNKEESCRDAAALSPKDEERESLN GORGOX_27_PE4 ENSGGOG00000023361 AGGPGSAPAAGGGTG-TEDDEEELL-------EDEEDEDEEE-----EL-LEDDEEELL- GORGOX_27_PE5 ISOFORMIN AGGPGSAPAAGGGTG-N------------------------------------------- HORSEX_20_PE4 NOISO -----------------------------------------------EL-LKDDEEELL- HSX_PE449 NOISO AGGPGSAPAAGGGTG-TEDDEEELL-------EDEEDEDEEE-----EL-LEDDEEELL- LOXAF39_7_PE1 ISOFORMIN NQGPRGGAARRGRAQSFQDSGDFLFFPGPKSVQNEKGKERKG-----ERGNEKDRQKSGE LOXAF39_7_PE2 ENSLAFG00000001779 NQGPRGGAARRGRAQSFQDSGVQ----------NEKIREKER-----EVMKKT-DRKVGK LOXAF39_7_PE3 ISOFORMIN ------------------------------------------------------------ MACEUGS_1794_PE2 NOISO VGGR---RRLLGPPG-PEDDEEELL-------EDEEEDDEEE-----EL-LEDDEEELL- MACMUX_24_PE5 NOISO AGGPGSAPAAGGGTG-TEDDEEELL-------EDEEDEDEEE-----EL-LEDDEEELL- MONDO4_41_PE1 NOISO VASAA--AATSGPPG-PEDDDEELL-------EDEEEDDEEE-----EL-LEDDEEELL- MOUSEX_PE1159 ENSMUSG00000035277 ASGPGSAPAAGGGTG-AEDDEEELL-------EDEEDEEEEE-----EL-LEDDDEELL- MOUSEX_PE1160 ISOFORMIN ASGPGSAPAAGGGTG-AEDDEEELL-------EDEEDEEEEE-----EL-LEDDDEELL- ORYLA20_14_PE18 NOISO ------------------DGSLGLVELGPLKFEDDAGKEEESCGDASALSPKDEEREGLN POEGU1_13_PE1 NOISO -------PAAPAAEE-EEEEEDEEM-------LEEEEDEEEE-----EL-EDDEEEELL- PONPYX_26_PE7 NOISO ------------------------------------------------------------ RABITX_12_PE2 NOISO ---AGSAPAARAGTP-GPADTLTTL-------PCPQAPLIAA-----SL-LEDDEEELL- RATX_PE669 ENSRNOG00000032074 ASGPGSAPAAGGGTG-TEEDEEEML-------EDEEDEDEEE-----EL-LEDDEEELL- RATX_PE670 ISOFORMIN ASGPGSAPAAGGGTG-TEEDEEEML-------EDEEDEDEEE-----EL-LEDDEEELL- SORARGS_26_PE1 NOISO AGGPGCAPRDGGRPG-AEDDEEELL-------EDDEDDVDEE-----EL-LEDDDEELL- SPETRGS_987_PE2 NOISO AGGPGSAPAA-GGAG-AEDDEEELL-------EDEEDEEEEE-----EL-LEDDEEELX- TARSYGS_29_PE1 NOISO AGGPGSAPAASGGTG-TEDDEEELL-------EDEEDEDEEE-----EL-LEXXXXXXX- TETNG6_PE76 NOISO ------------------DSSLGLVDLGPLKFEEEAGNKEESCGDAAALSPKDEERESLN TUPGBGS_380_PE4 NOISO ASGPGSAPAAGSGTG-AEDDEEELL-------EDEEDEDEEE-----EL-LEDDEEELL- XENTR64_2_PE6 NOISO LQDRLG--ALSQSPR-DEDDDDEED-------EDE-----EE-----EE-EEEDEANKQ- MATCH CONSENSUS ????????????????????????????????????????????????????????????

AILMEGL193473_1_PE1 NOISO EDAA----------------------------------------AVATEGGE-------- ANOCA775_PE2 NOISO ------------------------------------------------------------ BOVINX_74_PE2 NOISO VPSGSAPFPFTRVLGERCTCEMTGPLRAGL---VIP-------GMPAR------------ CALJAX_25_PE2 NOISO GLSPLAPAP----E-PACSAALDLLVLT----------------VAGGNGGHLWRRFSSG CANFAX_21_PE7 NOISO EDDARALLK----EPRRCAVAATGAVAAAA---AA-AAAA---AAVATEGGELS------ DANRE24_26_PE20 ENSDARG00000058011 HNDGDVKDG----EDSVCLSAGS------------------------------------- DANRE24_26_PE21 ISOFORMIN HNDGDVKDG----EDSVCLSAGS------------------------------------- DANREZV9_3460_PE2 NOISO ------------------------------------------------------------ FUGRU152_PE63 ENSTRUG00000007885 AGDGDVRDG----EDSVCLSAGS------------------------------------- FUGRU152_PE64 ISOFORMIN AGDGDVRDG----EDSVCLSAGS------------------------------------- GORGOX_27_PE4 ENSGGOG00000023361 EDDARALLK----EPRRCPVAATGAVAAA---------AA---AAVATEGGELS------ GORGOX_27_PE5 ISOFORMIN ---ARALLK----EPRRCPVAATGAVAAA---------AA---AAVATEGGELS------ HORSEX_20_PE4 NOISO KDDGRALLK----EPRRCAVAATARWAA---------AAS---AAVATEGGELS------ HSX_PE449 NOISO EDDARALLK----EPRRCPVAATGAVAAA---------AA---AAVATEGGELS------ LOXAF39_7_PE1 ISOFORMIN GDEGLGVGP---RGGGSGGVPGALTALPCP---QAP-----------PKAAAPSFEPSEG LOXAF39_7_PE2 ENSLAFG00000001779 ETKGWELDR---AE---G------AVAGCL---AAP-----------PKAAAPSFE--EG LOXAF39_7_PE3 ISOFORMIN ----------------------------------------------------------EG MACEUGS_1794_PE2 NOISO EDDGRGLLK----EPRRCPAATAAAAAA---------AAA---VAAAAEGGELS------ MACMUX_24_PE5 NOISO EDNARALLK----EPRRCAVAATGAVAAA---------AA---AAVVTEGGELS------ MONDO4_41_PE1 NOISO EDDGRGLLK----EPRRCTAATAAAAAAAA---AAAAAAA---AAAAAEGGELS------ MOUSEX_PE1159 ENSMUSG00000035277 EDDARALLK----EPRRCSVATTGTVAAAA---A---AAA---AAVATEGGELS------ MOUSEX_PE1160 ISOFORMIN EDDARALLK----EPRRCSVATTGTVAAAA---A---AAA---AAVATEGGELS------ ORYLA20_14_PE18 NOISO AGDGDVRDG----EDSVCLSAGS------------------------------------- POEGU1_13_PE1 NOISO GEDGGGLLKDARR------------------------GAT---AAPGAEGGD-------- PONPYX_26_PE7 NOISO ------------------------------------------------------------ RABITX_12_PE2 NOISO EDDARALLK--------------------------------------EQGG--------- RATX_PE669 ENSRNOG00000032074 EDDARALLK----EPRRCSVATTGTVAAAA---AA-AAAA---AAVATEGGELS------ RATX_PE670 ISOFORMIN EDDARALLK----EPRRCSVATTGTVAAAA---AA-AAAA---AAVATEGGELS------ SORARGS_26_PE1 NOISO D-DARALLK----KPRRCGVAAPGAVASAA---------A---AAVAPEGGELS------ SPETRGS_987_PE2 NOISO XXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-----------------XXXXXXX------ TARSYGS_29_PE1 NOISO XXXXXXXXX--------------------------------------------------- TETNG6_PE76 NOISO AGDGDVRDG----EDSVCLSAGSDTEEGMLKKDALPRRLHQVNRNSSPKN--------RK TUPGBGS_380_PE4 NOISO EDDARALLK----EPRRCAVATTGAVATAA---------A---AAVATEGGELS------ XENTR64_2_PE6 NOISO HN------PNNSSNPNRAHLQEQQHPQF---------------QSQQSQQQQPPPGCGTD MATCH CONSENSUS ????????????????????????????????????????????????????????????

AILMEGL193473_1_PE1 NOISO --LSPKEELLL--HPEDAEGKDGEDSVCLSAGSDSEEGLLKRKQRRYRTTFTSYQLEELE ANOCA775_PE2 NOISO ---SPKEELSL---LPGDEGKDGEDGVCLSAGSDSEEGLLKRKQRRYRTTFTSYQLEELE BOVINX_74_PE2 NOISO ------QGAFLS-HPKGEEPEE-----GKGDGSQPRLGLVKLEQPQLRTSRTHNSKEENE CALJAX_25_PE2 NOISO AEVSGVDWVLPA-GHLRVPGFSSPRSFILASGGPIILGALIFSSKNYPTELL-TSLTYLQ CANFAX_21_PE7 NOISO ----PKEELLL--HPEDAEGKDGEDSVCLSAGSDSEEGLLKRKQRRYRTTFTSYQLEELE DANRE24_26_PE20 ENSDARG00000058011 ---------------------------------DSEEGMLKRKQRRYRTTFTSYQLEELE DANRE24_26_PE21 ISOFORMIN ---------------------------------DSEEGMLKRKQRRYRTTFTSYQLEELE DANREZV9_3460_PE2 NOISO ---------F----------LKNSEETSLSAGSDTEDGMLKRKQRRYRTTFTSYQLEELE FUGRU152_PE63 ENSTRUG00000007885 ---------------------------------DTEEGMLKRKQRRYRTTFTSYQLEELE FUGRU152_PE64 ISOFORMIN ---------------------------------DTEEGMLKRKQRRYRTTFTSYQLEELE GORGOX_27_PE4 ENSGGOG00000023361 ----PKEELLL--HPEDAEGKDGEDSVCLSAGSDSEEGLLKRKQRRYRTTFTSYQLEELE GORGOX_27_PE5 ISOFORMIN ----PKEELLL--HPEDAEGKDGEDSVCLSAGSDSEEGLLKRKQRRYRTTFTSYQLEELE HORSEX_20_PE4 NOISO ----PKEELLL--HPEDAEGKDGEDSVCLSAGSDSEEGLLKRKQRRYRTTFTSYQLEELE HSX_PE449 NOISO ----PKEELLL--HPEDAEGKDGEDSVCLSAGSDSEEGLLKRKQRRYRTTFTSYQLEELE LOXAF39_7_PE1 ISOFORMIN GELSPKEELLP--PPEGAEGKDGRDCVCLFAGSDSEEGLLKRKQRRYRTTFTSYQLEELE LOXAF39_7_PE2 ENSLAFG00000001779 GELSPKEELLP--PPEGAEGKDGRDCVCLFAGSDSEEGLLKRKQRRYRTTFTSYQLEELE LOXAF39_7_PE3 ISOFORMIN GELSPKEELLP--PPEGAEGKDGRDCVCLFAGSDSEEGLLKRKQRRYRTTFTSYQLEELE MACEUGS_1794_PE2 NOISO ----PKEELLLH-PGEDAEGKDGEDSMCLSAGSDSEEGLLKRKQRRYRTTFTSYQLEELE MACMUX_24_PE5 NOISO ----PKEELLL--HPEDAEGKDGEDSVCLSAGSDSEEGLLKRKQRRYRTTFTSYQLEELE MONDO4_41_PE1 NOISO ----PKEELLLH-PGEDGEGKDGEDSVCLSAGSDSEEGLLKRKQRRYRTTFTSYQLEELE MOUSEX_PE1159 ENSMUSG00000035277 ----PKEELLL--HPEDAEGKDGEDSVCLSAGSDSEEGLLKRKQRRYRTTFTSYQLEELE MOUSEX_PE1160 ISOFORMIN ----PKEELLL--HPEDAEGKDGEDSVCLSAGSDSEEGLLKRKQRRYRTTFTSYQLEELE ORYLA20_14_PE18 NOISO ---------------------------------DSEEGMLKRKQRRYRTTFTSYQLEELE POEGU1_13_PE1 NOISO --LSPKEELLL--HPEDGEGKDGEESVCLSAGSDSEEGLLKRKQRRYRTTFTSYQLEELE PONPYX_26_PE7 NOISO ------------------------------------------------------------ RABITX_12_PE2 NOISO -ELSPKEELLL--HPEDTEGKDGEDSVCLSAGSDSEEGLLKRKQRRYRTTFTSYQLEELE RATX_PE669 ENSRNOG00000032074 ----PKEELLL--HPEDAEGKDGEDSVCLSAGSDSEEGLLKRKQRRYRTTFTSYQLEELE RATX_PE670 ISOFORMIN ----PKEELLL--HPEDAEGKDGEDSVCLSAGSDSEEGLLKRKQRRYRTTFTSYQLEELE SORARGS_26_PE1 NOISO ----PKEELLL--HPEDAEGKDGEDSVCLSAGSDSEEGLLKRKQRRYRTTFTSYQLEELE SPETRGS_987_PE2 NOISO ----XXXXXXXX-XXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX TARSYGS_29_PE1 NOISO -----------------------------------------------------X------ TETNG6_PE76 NOISO LQLSYRENAYLRRGEGDQSPGEGSESVCLSAGSDTEEGMLKRKQRRYRTTFTSYQLEELE TUPGBGS_380_PE4 NOISO ----PKEELLL--HPEDAEGKDGEDSVCLSAGSDSEEGLLKRKQRRYRTTFTSYQLEELE XENTR64_2_PE6 NOISO AELSPKEELML--HSSDADGKDGEDSVCLSAGSDSEEGMLKRKQRRYRTTFTSYQLEELE MATCH CONSENSUS ?????????????????????????????????D?EEG?LKRKQRRYRTTFTSYQLEELE

AILMEGL193473_1_PE1 NOISO -RAFQKTHYPDVFT--REELAMRLDLTEA-RVQVSIAAERERERGRGKGGEKSGDPGLIT ANOCA775_PE2 NOISO -RAFQKTHYPDVFT--REELAMRLDLTEA-RVQVWFQNRRAKWRKREKAGAQSHPPGLPF BOVINX_74_PE2 NOISO VMSLGTQVCPFSFS--REELAMRLDLTEA-RVQVWFQNRRAKWRKREKAGAQTHPPGLPF CALJAX_25_PE2 NOISO -RKGQKSIFLKLWL--KEELAMRLDLTEA-RVQVWFQNRRAKWRKREKAGAQTHPPGLPF CANFAX_21_PE7 NOISO -RAFQKTHYPDVFT--REELAMRLDLTEA-RVQVWFQNRRAKWRKREKAGAQTHPPGLPF DANRE24_26_PE20 ENSDARG00000058011 -RAFQKTHYPDVFT--REELAMRLDLTEA-RVQVWFQNRRAKWRKREKAGVQAHPTGLPF DANRE24_26_PE21 ISOFORMIN -RAFQKTHYPDVFT--REELAMRLDLTEA-RVQVWFQNRRAKWRKREKAGVQAHPTGLPF DANREZV9_3460_PE2 NOISO -RAFQKTHYPDVFTSLREELAMRLDLTEA-RVQVWFQNRRAKWRKREKVGVQPHTLSLHY FUGRU152_PE63 ENSTRUG00000007885 -RAFQKTHYPDVFT--REELAMRLDLTEA-RVQVWFQNRRAKWRKREKAGVQAHPSGLPF FUGRU152_PE64 ISOFORMIN -RAFQKTHYPDVFT--REELAMRLDLTEA-RVQVWFQNRRAKWRKREKAGVQAHPSGLPF GORGOX_27_PE4 ENSGGOG00000023361 -RAFQKTHYPDVFT--REELAMRLDLTEA-RVQVWFQNRRAKWRKREKAGAQTHPPGLPF GORGOX_27_PE5 ISOFORMIN -RAFQKTHYPDVFT--REELAMRLDLTEA-RVQVWFQNRRAKWRKREKAGAQTHPPGLPF HORSEX_20_PE4 NOISO -RAFQKTHYPDVFT--REELAMRLDLTEA-RVQVWFQNRRAKWRKREKAGAQSHPPGLPF HSX_PE449 NOISO -RAFQKTHYPDVFT--REELAMRLDLTEA-RVQVWFQNRRAKWRKREKAGAQTHPPGLPF LOXAF39_7_PE1 ISOFORMIN -RAFQKTHYPDVFT--REELAMRLDLTEA-RVQVWFQNRR-KWRKRERRAR-RPTLGLPF LOXAF39_7_PE2 ENSLAFG00000001779 -RAFQKTHYPDVFT--REELAMRLDLTEA-RVQVWFQNRR-KWRKRERRAR-RPTLGLPF LOXAF39_7_PE3 ISOFORMIN -RAFQKTHYPDVFT--REELAMRLDLTEA-RVQVWFQNRR-PKSSAERKST-G---ERPH MACEUGS_1794_PE2 NOISO -RAFQKTHXXX-XX--XEELAMRLDLTEA-RVQVWFQNRRAKWRKREKAGAQTHPPGLPF MACMUX_24_PE5 NOISO -RAFQKTHYPDVFT--REELAMRLDLTEA-RVQVWFQNRRAKWRKREKAGAQTHPPGLPF MONDO4_41_PE1 NOISO -RAFQKTHYPDVFT--RKQMSLGLKLSKSLYRQVWFQNRRAKWRKREKAGAQTHPPGLPF MOUSEX_PE1159 ENSMUSG00000035277 -RAFQKTHYPDVFT--REELAMRLDLTEA-RVQVWFQNRRAKWRKREKAGAQTHPPGLPF MOUSEX_PE1160 ISOFORMIN -RAFQKTHYPDVFT--REELAMRLDLTEA-RVQVWFQNRRAKWRKREKAGAQTHPPGLPF ORYLA20_14_PE18 NOISO -RAFQKTHYPDVFT--REELAMRLDLTEA-RVQVWFQNRRAKWRKREKAGVQAHPPGLPF POEGU1_13_PE1 NOISO -RAFQKTHYPDVFT--REELAMRLDLTEA-RVQVWFQNRRAKWRKREKAGAQTHPPGLPF PONPYX_26_PE7 NOISO -------------------LAMRLDLTEA-RVQVWFQNRRAKWRKREKAGAQTHPPGLPF RABITX_12_PE2 NOISO -RAFQKTHYPDVFT--REELAMRLDLTEA-RVQVWFQNRRAKWRKREKAGAQTHPPGLPF RATX_PE669 ENSRNOG00000032074 -RAFQKTHYPDVFT--REELAMRLDLTEA-RVQVWFQNRRAKWRKREKAGAQTHPPGLPF RATX_PE670 ISOFORMIN -RAFQKTHYPDVFT--REELAMRLDLTEA-RVQVWFQNRRAKWRKREKAGAQTHPPGLPF SORARGS_26_PE1 NOISO -RAFQKTHYPDVFT--RKKLAMRLDLTEA-RVQVWFQNRRAKWRKREKAGAQTHPPGLPF SPETRGS_987_PE2 NOISO XXXXXXXXXXXXXX--XEELAMRLDLTEA-RVQVWFQNRRAKWRKREKAGAQTHPPGLPF TARSYGS_29_PE1 NOISO -----------------------------------XXXXXXXXXXXXXXXXXTHPPRAPF TETNG6_PE76 NOISO -RAFQKTHYPDVFT--REELAMRLDLTEA-RVQVWFQNRRAKWRKREKAGVQAHPPGLAF TUPGBGS_380_PE4 NOISO -RAFQKTHYPDVFT--XXXXXXXXXXXXX-XXXVWFQNRRAKWRKREKAGAQTHPPGLPF XENTR64_2_PE6 NOISO -RAFQKTHYPDVFT--REELAMRLDLTEA-RVQVWFQNRRAKWRKREKAGAQTHAPGLPF MATCH CONSENSUS ?RAFQKTHYPDVFT??REELAMRLDLTEA?RVQVWFQNRRAKWRKREKAG?Q?HP?GLPF

AILMEGL193473_1_PE1 NOISO KETINTG------QPRWPTENR-CPWLPH-FREL---PPYNVC---LFAGANPAFPSLPP ANOCA775_PE2 NOISO PGPLSAS------HPLSPYLDASSPFPPH-HPAL---DSAWTAAAAAAAAAAAAFPGLPP BOVINX_74_PE2 NOISO PGPLSAT------HPLSPYLDA-SPFPPH-HPAL---DSAWTAAAA---AAAAAFPSLP- CALJAX_25_PE2 NOISO PGPLSAT------HPLSPYLDA-SPFPPH-HPAL---DSAWI-------------PSLP- CANFAX_21_PE7 NOISO PGPLSAT------HPLSPYLDA-SPFPPH-HPAL---DSAWTAAAA---AAAAAFPSLP- DANRE24_26_PE20 ENSDARG00000058011 PGPLAAA------HPLSHYLEG-GPFPPHPHPAL---ESAWTAAAA----AAAAFPGLAP DANRE24_26_PE21 ISOFORMIN PGPLAAA------HPLSHYLEG-GPFPPHPHPAL---ESAWTAAAA----AAAAFPGLAP DANREZV9_3460_PE2 NOISO SGAPPAA------QSLCHYLSG-NPFVPNPHPAI---DSAWPAP----------FQRLAQ FUGRU152_PE63 ENSTRUG00000007885 PGPLAAG------HPLSHYLEG-GPFPHHPHPAL---ESAWTAAAA----AAAAFPGLAP FUGRU152_PE64 ISOFORMIN PGPLAAG------HPLSHYLEG-GPFPHHPHPAL---ESAWTAAAA----AAAAFPGLAP GORGOX_27_PE4 ENSGGOG00000023361 PGPLSAT------HPLSPYLDA-SPFPPH-HPAL---DSAWTAAAA---AAAAAFPSLP- GORGOX_27_PE5 ISOFORMIN PGPLSAT------HPLSPYLDA-SPFPPH-HPAL---DSAWI-------------PSLP- HORSEX_20_PE4 NOISO PGPLSAT------HPLSPYLDA-SPFPPH-HPAL---DSAWTAAAA---AAAAAFPSLP- HSX_PE449 NOISO PGPLSAT------HPLSPYLDA-SPFPPH-HPAL---DSAWTAAAA---AAAAAFPSLP- LOXAF39_7_PE1 ISOFORMIN PGPLSPP--------IRPFLAPVQPSLCA-QPRVLAPPAPRARGHPG-------LVA--- LOXAF39_7_PE2 ENSLAFG00000001779 PGPLSPP--------IRPFLAPVQPSLCA-QPRVLAPPAPRARGHPG-------LVA--- LOXAF39_7_PE3 ISOFORMIN PPPLPPRGQGAGGLPRRRLLAGRR---AH-KPAFPAPAQSWAEKEPGRG----GFQR--- MACEUGS_1794_PE2 NOISO PGPLSAT------HPLSPYLDA-SPFPPH-HPAL---DSAWTAAAA---AAAAAFPSLP- MACMUX_24_PE5 NOISO PGPLSAT------HPLSPYLDA-SPFPPH-HPAL---DSAWTAAAA---AAAAAFPSLP- MONDO4_41_PE1 NOISO PGPLSAT------HPLSPYLDA-SPFPPH-HPAL---DSAWTAAAA---AAAAAFPSLP- MOUSEX_PE1159 ENSMUSG00000035277 PGPLSAT------HPLSPYLDA-SPFPPH-HPAL---DSAWTAAAA---AAAAAFPSLP- MOUSEX_PE1160 ISOFORMIN PGPLSAT------HPLSPYLDA-SPFPPH-HPAL---DSAWTAAAA---AAAAAFPSLP- ORYLA20_14_PE18 NOISO PGPLSAG------HPLSHYLEG-GPFPPHPHPAL---ESAWTAAAA----AAAAFPSLAP POEGU1_13_PE1 NOISO PGPLSAT------HPLSPYLDA-SPFPPH-HPAL---DSAWTAAAA---AA-AAFPSLPP PONPYX_26_PE7 NOISO PGPLSAT------HPLSPYLDA-SPFPPH-HPAL---DSAWTAAAA---AAAAAFPSLP- RABITX_12_PE2 NOISO PGPLSAT------HPLSPYLDA-SPFPPH-HPAL---DSAWI-------------PSLP- RATX_PE669 ENSRNOG00000032074 PGPLSAT------HPLSPYLDA-SPFPPH-HPAL---DSAWTAAAA---AAAAAFPSLP- RATX_PE670 ISOFORMIN PGPLSAT------HPLSPYLDA-SPFPPH-HPAL---DSAWTAAAA---AAAAAFPSLP- SORARGS_26_PE1 NOISO PGPLSAT------HPLSPYLDA-SPFPPH-HPAL---DSAWTAAAA---AAAAAFPSLP- SPETRGS_987_PE2 NOISO PGPLSAT------HPLSPYLDA-SPFPPH-HPAL---DSAWTAAAAA---AAAAFPL--P TARSYGS_29_PE1 NOISO PEPLSAT------HPLSPYLDA-SPFPPH-HPAL---DSAWTAAAA---AAAAAFPSLP- TETNG6_PE76 NOISO PGPLAAG------HPLSHYLEG-GPFPHHPHPAL---ESAWTAAAA----AAAAFPGLAP TUPGBGS_380_PE4 NOISO PEPLSAT------HPLSPYLDA-SPFPPH-HPAL---DSAWTAAAA---AAAAAFPSLP- XENTR64_2_PE6 NOISO PGPLSAS------HPLGPYLDA-SPFPPH-HPAL---DSAWTAAAA---AAAAAFPSLPP MATCH . . . CONSENSUS PGPL?A???????HPLS?YL????PFPPH?HPAL????SAW?????????????FP?L??

AILMEGL193473_1_PE1 NOISO PPPGSAS--LPPSGAPLGLSTFLG-AAVFRHPAFISPAFGRLFSTMAPLTSARA------ ANOCA775_PE2 NOISO PPPGSSAALAPGAGAPLGLSTFLG-AAVFRHPAFISPAFGRLFSTMAPLTSASTAAAALL BOVINX_74_PE2 NOISO PPPGSAS--LPPSGAPLGLSTFLG-AAVFRHPAFISPAFGRLFSTMAPLTSASTAA-ALL CALJAX_25_PE2 NOISO PPPGSAS--LPPSGAPLGLSTFLG-AAVFRHPAFISPAFGRLFSTMAPLTSASTAA-ALL CANFAX_21_PE7 NOISO PPPGSAS--LPPSGAPLGLSTFLG-AAVFRHPAFISPAFGRLFSTMAPLTSASTAA-ALL DANRE24_26_PE20 ENSDARG00000058011 PPNSSA---L-PPATPLGLGTFLGT-AMFRHPAFIGPTFGRLFSSMGPLTSASTAA-ALL DANRE24_26_PE21 ISOFORMIN PPNSSA---L-PPATPLGLGTFLGT-AMFRHPAFIGPTFGRLFSSMGPLTSAST------ DANREZV9_3460_PE2 NOISO PAQNSV---SP-----PGFSALLG-AAMFRHPAFFNPTFGRLFTSLGPMAL--------Q FUGRU152_PE63 ENSTRUG00000007885 PHHNGS---APPLASPLGLGTFLGTAAMFRHPAFIGPHFGRLFSSMGPLTSASTAA-ALL FUGRU152_PE64 ISOFORMIN PHHNGS---APPLASPLGLGTFLGTAAMFRHPAFIGPHFGRLFSSMGPLTSASTAA-ALL GORGOX_27_PE4 ENSGGOG00000023361 PPPGSAS--LPPSGAPLGLSTFLG-AAVFRHPAFISPAFGRLFSTMAPLTSASTAA-ALL GORGOX_27_PE5 ISOFORMIN PPPGSAS--LPPSGAPLGLSTFLG-AAVFRHPAFISPAFGRLFSTMAPLTSASTAA-ALL HORSEX_20_PE4 NOISO PPPGSAS--LPPSGAPLGLSTFLG-AAVFRHPAFISPAFGR------------------- HSX_PE449 NOISO PPPGSAS--LPPSGAPLGLSTFLG-AAVFRHPAFISPAFGRLFSTMAPLTSASTAA-ALL LOXAF39_7_PE1 ISOFORMIN A-PRGRTVCAPRAPGERGRPTWRR-AP-LRGRDRAVCSPRRLFSTMAPLTSASTAA-ALL LOXAF39_7_PE2 ENSLAFG00000001779 A-PRGRTVCAPRAPGERGRPTWRR-AP-LRGRDRAVCSPRRLFSTMAPLTSASTAA-ALL LOXAF39_7_PE3 ISOFORMIN LGLAATRAWLPPPAAAPGRPTWRR-AP-LRGRDRAVCSPRRLFSTMAPLTSASTAA-ALL MACEUGS_1794_PE2 NOISO PPPGSAT--LPPSGTPLGLSTFLG-AAVFRHPAFISPAFGRLFSTMAPLTSASTAA-ALL MACMUX_24_PE5 NOISO PPPGSAS--LPPSGAPLGLSTFLG-AAVFRHPAFISPAFGRLFSTMAPLTSASTAA-ALL MONDO4_41_PE1 NOISO PPPGSAT--LPPSGTPLGLSTFLG-AAVFRHPAFISPAFGRLFSTMAPLTSASTAA-ALL MOUSEX_PE1159 ENSMUSG00000035277 PPPGSAS--LPPSGAPLGLSTFLG-AAVFRHPAFISPAFGRLFSTMAPLTSASTAA-ALL MOUSEX_PE1160 ISOFORMIN PPPGSAS--LPPSGAPLGLSTFLG-AAVFRHPAFISPAFGRLFSTMAPLTSASTAA-ALL ORYLA20_14_PE18 NOISO PPHNGS---APPLATPLGLGTFLGTAAMFRHPAFIGPTFGRLFSSMGPLTSASTAA-ALL POEGU1_13_PE1 NOISO PPPGSAA--LPPGGTPLGLGTFLG-WDGFRHPAFINPAFGRLFSTMSPLGSASSAA-ALL PONPYX_26_PE7 NOISO PPPGSAS--LPPSGAPLGLSTFLG-AAVFRHPAFISPAFGRLFSTMAPLTSASTAA-ALL RABITX_12_PE2 NOISO PPPGSAS--LPPSGAPLGLSTFLG-AAVFRHPAFISPAFGRLFSTMAPLTSASTAA-ALL RATX_PE669 ENSRNOG00000032074 PPPGSAS--LPPSGAPLGLSTFLG-AAVFRHPAFISPAFGRLFSTMAPLTSASTAA-ALL RATX_PE670 ISOFORMIN PPPGSAS--LPPSGAPLGLSTFLG-AAVFRHPAFISPAFGRLFSTMAPLTSASTAA-ALL SORARGS_26_PE1 NOISO PPPGSAS--LPPSGAPLGLSTFLG-AAVFRHPAFISPAFGRLFSTMAPLTSASTAA-ALL SPETRGS_987_PE2 NOISO PPPGSAS--LPPSGXXXXXXXXXX-XXXXXXXXXXXXXX---XXXXXXXXXXTNASAIAL TARSYGS_29_PE1 NOISO PPPGSAS--LPPSGAPLGLSTFLG-AAVFRHPAFISPAFG-------------------- TETNG6_PE76 NOISO PHHNGY---RPPLAAPLGLGTFLGTAAMFRHPAFIGPHFGRLFSSMGPLTSASTAA-ALL TUPGBGS_380_PE4 NOISO PPPGSAS--LPPSGAPLGLSTFLG-AAVFRHPAFISPAFGRLFSTMAPLTSASTAA-ALL XENTR64_2_PE6 NOISO PPHGSAA--LPPSGSPLGLSTFLG-AAVFRHPAFISPAFGRLFSTMAPLTSASTAA-ALL MATCH . CONSENSUS P?????????PP???PLGL?TFLG?AA?FRHPAFI?P?FGRLFS?M?PLTSASTAA?ALL

AILMEGL193473_1_PE1 NOISO -----------------------ALADPA-TAAADRRASSIAALRLKAKEHAAQLTQLNI ANOCA775_PE2 NOISO RQPSPAAVESAVHSGGGGGGG-GGLSDPLAAAAADRRASSIAALRLKAKEHAAQLTQLNI BOVINX_74_PE2 NOISO RQPTPAV-EGAV-------AS-GALADPA-TAAADRRASSIAALRLKAKEHAAQLTQLNI CALJAX_25_PE2 NOISO RQPTPAV-EGAV-------AS-GALADPA-TAAADRRASSIAALRLKAKEHAAQLTQLNI CANFAX_21_PE7 NOISO RQPTPAV-EGAV-------AS-GALADPA-TVAADRRASSIAALRLKAKEHAAHLTQLNI DANRE24_26_PE20 ENSDARG00000058011 RQTAPPV-ESPVQPSAALPEPPSSS--S--STAADRRASSIAALRLKAKEHSAQLTQLNI DANRE24_26_PE21 ISOFORMIN ------------------------------------------------------------ DANREZV9_3460_PE2 NOISO RIPLPAI-EGPIQRSHLTTSLLSSSPPLPSSPTVDLRASSIAALRLKAKEHSAQLTHI-- FUGRU152_PE63 ENSTRUG00000007885 RQPAPAV-ENPSHAGPVLPDPSNSS--PSSSSSADRRASSIAALRLKAKEHSAQLTQLNI FUGRU152_PE64 ISOFORMIN RQPAPAV-ENPSHAGPVLPDPSNSS--PSSSSSADRRASSIAALRLKAKEHSAQLTQLNI GORGOX_27_PE4 ENSGGOG00000023361 RQPTPAV-EGAV-------AS-GALADPA-TAAADRRASSIAALRLKAKEHAAQLTQLNI GORGOX_27_PE5 ISOFORMIN RQPTPAV-EGAV-------AS-GALADPA-TAAADRRASSIAALRLKAKEHAAQLTQLNI HORSEX_20_PE4 NOISO ------------------------------------------------------------ HSX_PE449 NOISO RQPTPAV-EGAV-------AS-GALADPA-TAAADRRASSIAALRLKAKEHAAQLTQLNI LOXAF39_7_PE1 ISOFORMIN RQPTPAV-EGAV-------AS-GALADPA-TAAADRRASSIAALRLKAKEHAAQLTQLNI LOXAF39_7_PE2 ENSLAFG00000001779 RQPTPAV-EGAV-------AS-GALADPA-TAAADRRASSIAALRLKAKEHAAQLTQLNI LOXAF39_7_PE3 ISOFORMIN RQPTPAV-EGAV-------AS-GALADPA-TAAADRRASSIAALRLKAKEHAAQLTQLNI MACEUGS_1794_PE2 NOISO RQPTPAV-DGGV-------QS-SALSDPA-TAAADRRASSIAALRLKAKEHAAQLTQLNI MACMUX_24_PE5 NOISO RQPTPAV-EGAV-------AS-GALADPA-TAAADRRASSIAALRLKAKEHAAQLTQLNI MONDO4_41_PE1 NOISO RQPTPAV-DSGV-------QS-SALSDPA-TAAADRRASSIAALRLKAKEHAAQLTQLNI MOUSEX_PE1159 ENSMUSG00000035277 RQPTPAV-EGAV-------AS-GALADPA-TAAADRRASSIAALRLKAKEHAAQLTQLNI MOUSEX_PE1160 ISOFORMIN RQPTPAV-EGAV-------AS-GALADPA-TAAADRRASSIAALRLKAKEHAAQLTQLNI ORYLA20_14_PE18 NOISO RQPAPPV-ENPSHASSVLPDPSSSS--SSTSAAADRRASSIAALRLKAKEHSAQLTQLNI POEGU1_13_PE1 NOISO RQPAPAA-EGAV-------GS-AGLGDPA-SAAADRRASSIAALRLKAKEHAAQLTQLNI PONPYX_26_PE7 NOISO RQPTPAV-EGAV-------AS-GALADPA-TAAADRRASSIAALRLKAKEHAAQLTQLNI RABITX_12_PE2 NOISO RQPAPAV-EGAV-------AS-GALADPA-TAAADRRASSIAALRLKAKEHAAQLTQLNI RATX_PE669 ENSRNOG00000032074 RQPTPAV-EGAV-------AS-GALADPA-TAAADRRASSIAALRLKAKEHAAQLTQLNI RATX_PE670 ISOFORMIN RQPTPAV-EGAV-------AS-GALADPA-TAAADRRASSIAALRLKAKEHAAQLTQLNI SORARGS_26_PE1 NOISO RQPTPAV-EGAV-------AS-GALADPA-TAAADRRASSIAALRLKAKEHAAQLTQLNI SPETRGS_987_PE2 NOISO RQPTFEM-EGAV-------GS-GALADAA-PAAADRRASSIEALRLKTKEDAAQLTQLNI TARSYGS_29_PE1 NOISO ------------------------------------------------------------ TETNG6_PE76 NOISO RQPAPAV-ENPPHAGPVLPDPSSSS--R------GPQASSIAALRLKAKEHSAQLTQLNI TUPGBGS_380_PE4 NOISO RQPTPAV-EGAV-------AS-GALADPA-TAAADRRASSIAALRLKAKEHAAQLTQLNI XENTR64_2_PE6 NOISO RQPSPAV-ESSV-------QS-SGLSDPV-TAAADRRASSIAALRLKAKEHAAQLTQLNI MATCH CONSENSUS RQP?P???E????????????????????????ADRRASSIAALRLKAKEH?AQLTQLNI

AILMEGL193473_1_PE1 NOISO LPGTS-TGKEVC ANOCA775_PE2 NOISO LPGNSAAGKEVC BOVINX_74_PE2 NOISO LPGTS-TGKEVC CALJAX_25_PE2 NOISO LPGTS-TGKEVC CANFAX_21_PE7 NOISO LAGTS-TGKEVC DANRE24_26_PE20 ENSDARG00000058011 LPSGT-AGKEVC DANRE24_26_PE21 ISOFORMIN ------------ DANREZV9_3460_PE2 NOISO TAAGT-AGKEEC FUGRU152_PE63 ENSTRUG00000007885 LPAGA-AGKEVC FUGRU152_PE64 ISOFORMIN LPAGA-AGKEVC GORGOX_27_PE4 ENSGGOG00000023361 LPGTS-TGKEVC GORGOX_27_PE5 ISOFORMIN LPGTS-TGKEVC HORSEX_20_PE4 NOISO ------------ HSX_PE449 NOISO LPGTS-TGKEVC LOXAF39_7_PE1 ISOFORMIN LPGTS-TGKEVC LOXAF39_7_PE2 ENSLAFG00000001779 LPGTS-TGKEVC LOXAF39_7_PE3 ISOFORMIN LPGTS-TGKEVC MACEUGS_1794_PE2 NOISO LPGNS-TGKEVC MACMUX_24_PE5 NOISO LPGTS-TGKEVC MONDO4_41_PE1 NOISO LPGNS-TGKEVC MOUSEX_PE1159 ENSMUSG00000035277 LPGTS-TGKEVC MOUSEX_PE1160 ISOFORMIN LPGTS-TGKEVC ORYLA20_14_PE18 NOISO LPAGA-AGKEVC POEGU1_13_PE1 NOISO LPGNS-TGKEVC PONPYX_26_PE7 NOISO LPGTS-TGKEVC RABITX_12_PE2 NOISO LPGTS-TGKEVC RATX_PE669 ENSRNOG00000032074 LPGTS-TGKEVC RATX_PE670 ISOFORMIN LPGTS-TGKEVC SORARGS_26_PE1 NOISO LPGTS-TGKEVC SPETRGS_987_PE2 NOISO LPGTS-TGKEVC TARSYGS_29_PE1 NOISO ------------ TETNG6_PE76 NOISO LPAGA-AGKEVC TUPGBGS_380_PE4 NOISO LPGTS-TGKEVC XENTR64_2_PE6 NOISO IPGNS-AGKEVC MATCH CONSENSUS LP?????GKEVC


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