Alignment of the gene Family HOG000013012 of HOGENOM

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Isoforms are ON
AILMEGL193619_1_PE3 NOISO --------------------------------------------------------------------------------RIAYQRNDDD-EEEAARERRRRARQERLRQKQEEESLGQ- ANOCA90_1_PE4 NOISO -------------------------------------------------------MDDFERRREL--RRQKREEMRLESERLAYQRNDDDDDEEAARERRRRARQERLRHKEDDDLTGQ- BOVIN4_107_PE3 ENSBTAG00000013953 --------------------------------------------------------------------------------RIAYQRNDDD-EEEAARERRRRARQERLRQKQEEEALGQ- CALJA8_118_PE4 ENSCJAG00000012295 -------------------------------------------------------MDDFERRR--ELRRQKREEMRLEAERIAYQRNDDD-EEEAARERRRRARQERLRQKQEEESLGQ- CALJA8_118_PE5 ISOFORMIN -------------------------------------------------------MDDFERRR--ELRRQKREEMRLEAERIAYQRNDDD-EEEAARERRRRARQERLRQKQEEESLGQ- CALJA8_118_PE6 ISOFORMIN -------------------------------------------------------MDDFERRR--ELRRQKREEMRLEAERIAYQRNDDD-EEEAARERRRRARQERLRQKQEEESLGQ- CALJA8_118_PE7 ISOFORMIN ---------------------------------------------------------------MLGGSGSHGRRSLAALSQIAYQRNDDD-EEEAARERRRRARQERLRQKQEEESLGQ- CALJA8_118_PE8 ISOFORMIN -------------------------------------------------------LDDYKSEKELGRK--TKSKQRRYSSPIAYQRNDDD-EEEAARERRRRARQERLRQKQEEESLGQ- CALJA8_118_PE9 ISOFORMIN ------------------------------------------------------PYIKVDRQWNAERLELILGSGQLSTGQIAYQRNDDD-EEEAARERRRRARQERLRQKQEEESLGQ- CANFA16_17_PE5 NOISO --------------------------------------------------------------------------------RIAYQRNDDD-EEEAARERRRRARQERLRQKQEEESLGQ- CAVPO10_14_PE12 ENSCPOG00000023504 -------------------------------------------------------MDDFERRR--ELRRQKREEMRLEAERIAYQRNDDD-EEEAARERRRRARQERLRQKQEEESLGQ- CAVPO10_14_PE13 ISOFORMIN --------------------------------------------------------------------------MSLQCCRIAYQRNDDD-EEEAARERRRRARQERLRQKQEEESLGQ- CHICK1_PE1105 ISOFORMIN --------------------------------------------------------------------------MRLEAERLSYQRNDDD-EEEAARERRRRARQERLRQKEEGDVSGE- CHICK1_PE1106 ISOFORMIN --------------------------------------------------------------------------MRLEAERLSYQRNDDD-EEEAARERRRRARQERLRQKEEGDVSGE- CHICK1_PE1107 ISOFORMIN --------------------------------------------------------------------------MRLEAERLSYQRNDDD-EEEAARERRRRARQERLRQKEEGDVSGE- CHICK1_PE1108 ENSGALG00000013071 -------------------------------------------------------MDDFERRREL--RRQKREEMRLEAERLSYQRNDDD-EEEAARERRRRARQERLRQKEEGDVSGE- CHOHOGS_2782_PE1 NOISO -------------------------------------------------------MDDFERRREL--RRQKREEM--XXILIAYQRNDDD-EEEAARERRRRARQERLRQKQEEESMGQ- ECHTEGS_2967_PE1 NOISO -------------------------------------------------------MDDFDRRREL--RRQKREEMRLEAERIAYQRNDDD-EEEAARERRRRARQERLRQKQEEESLGQ- FELCAGS_1637_PE1 NOISO -------------------------------------------------------MDDFERRREL--RRQKREEMRLEAERIAYQRNDDD-EEEAARERRRRARQERLRQKQEEESLGQ- FUGRU2_4_PE79 ENSTRUG00000016845 --------------------------------------------------------DDFDRRMEL--RRQRREQMRLDAQTIGVANDD---DEEEAREQRRRAREERKKMREVELA-GT- FUGRU2_4_PE80 ISOFORMIN --------------------------------------------------------DDFDRRMEL--RRQRREQMRLDAQTIGVANDD---DEEEAREQRRRAREERKKMREVELA-GT- GASACGROUPXIX_6_PE49 NOISO --------------------------------------------------------DDFERRMEQ--RRLRREQMRVDTDKDGYTNDD----EEEAREQRRRAREERKKMRDSDEP-GA- GORGO7_137_PE8 ENSGGOG00000009728 -------------------------------------------------------MDDFERRR--ELRRQKREEMRLEAERIAYQRNDDD-EEEAARERRRRARQERLRQKQEEESLGQ- GORGO7_137_PE9 ISOFORMIN --------------------------------------------------------------------------MRLEAERIAYQRNDDD-EEEAARERRRRARQERLRQKQEEESLGQ- HORSE4_93_PE3 NOISO ---------------------------------------------------------------MLGGSGSQGRRSLAALSQIAYQRNDDD-EEEAARERRRRARQERLRQKQEEESLGQ- HS7_PE3870 ISOFORMIN -------------------------------------------------------MDDFERRR--ELRRQKREEMRLEAERIAYQRNDDD-EEEAARERRRRARQERLRQKQEEESLGQ- HS7_PE3871 ISOFORMIN -------------------------------------------------------MDDFERRR--ELRRQKREEMRLEAERIAYQRNDDD-EEEAARERRRRARQERLRQKQEEESLGQ- HS7_PE3872 ISOFORMIN -------------------------------------------------------MDDFERRR--ELRRQKREEMRLEAERIAYQRNDDD-EEEAARERRRRARQERLRQKQEEESLGQ- HS7_PE3875 ENSG00000122786 -------------------------------------------------------MDDFERRR--ELRRQKREEMRLEAERIAYQRNDDD-EEEAARERRRRARQERLRQKQEEESLGQ- HS7_PE3876 ISOFORMIN -------------------------------------------------------MDDFERRR--ELRRQKREEMRLEAERIAYQRNDDD-EEEAARERRRRARQERLRQKQEEESLGQ- HS7_PE3879 ISOFORMIN ---------------------------------------------------------------MLGGSGSHGRRSLAALSQIAYQRNDDD-EEEAARERRRRARQERLRQKQEEESLGQ- HS7_PE3880 ISOFORMIN ---------------------------------------------------------------MLGGSGSHGRRSLAALSQIAYQRNDDD-EEEAARERRRRARQERLRQKQEEESLGQ- HS7_PE3881 ISOFORMIN ---------------------------------------------------------------MLGGSGSHGRRSLAALSQIAYQRNDDD-EEEAARERRRRARQERLRQKQEEESLGQ- HS7_PE3882 ISOFORMIN -------------------------------------------------------MDDFERRR--ELRRQKREEMRLEAERIAYQRNDDD-EEEAARERRRRARQERLRQKQEEESLGQ- HS7_PE3883 ISOFORMIN ---------------------------------------------------------------MLGGSGSHGRRSLAALSQIAYQRNDDD-EEEAARERRRRARQERLRQKQEEESLGQ- LOXAF101_1_PE8 NOISO ---------------------------------------------------------------LLSLCSYTAHDCLGVSCRIAYQRNDDD-EEEAARERRRRARQERLRQKQEEEALGQ- MACEUGS_3523_PE1 NOISO -------------------------------------------------------MDDFERRREL--RRQKREEMRLEAERIAYQRNDDD-EEEAARERRRRARQERLRQREEEESLGQ- MACMU3_178_PE13 ENSMMUG00000006527 -------------------------------------------------------MDDFERRR--ELRRQKREEMRLEAERIAYQRNDDD-EEEAARERRRRARQERLRQKQEEESLGQ- MACMU3_178_PE14 ISOFORMIN ---------------------------------------------------------------MLGGSGSHGRRSLAALSKIAYQRNDDD-EEEAARERRRRARQERLRQKQEEESLGQ- MACMU3_178_PE15 ISOFORMIN ---------------------------------------------------------------MLGGSGSHGRRSLAALSKIAYQRNDDD-EEEAARERRRRARQERLRQKQEEESLGQ- MACMU3_178_PE16 ISOFORMIN --------------------------------------------------------------------------------RIAYQRNDDD-EEEAARERRRRARQERLRQKQEEESLGQ- MICMUGS_3600_PE2 NOISO -------------------------------------------------------MDDFERRREL--RRQKREEMRLEAERIAYQRNDDD-EEEAARERRRARQKLQ-----SREILGVT MONDO8_203_PE5 ENSMODG00000014124 --------------------------------------------------------------------------------RIAYQRNDDD-EEEAARERRRRARQERLRQREEEESLGQ- MONDO8_203_PE6 ISOFORMIN ------------------------------------------------------------------------------------------------------------------------ MONDO8_203_PE7 ISOFORMIN ------------------------------------------------------------------------------------------------------------------------ MONDO8_203_PE8 ISOFORMIN ------------------------------------------------------------------------------------------------------------------------ MOUSE6_PE402 ISOFORMIN -------------------------------------------------------MDDFERRRELRRQ--KREEMRLEAERIAYQRNDDD-EEEAARERRRRARQERLRQKQEEESLGQ- MOUSE6_PE404 ISOFORMIN -------------------------------------------------------MDDFERRRELRRQ--KREEMRLEAERIAYQRNDDD-EEEAARERRRRARQERLRQKQEEESLGQ- MOUSE6_PE405 ISOFORMIN -------------------------------------------------------MDDFERRRELRRQ--KREEMRLEAERIAYQRNDDD-EEEAARERRRRARQERLRQKQEEESLGQ- MOUSE6_PE406 ISOFORMIN ---------------------------------------------------------------MLSGSGSQGRRCLATLSQIAYQRNDDD-EEEAARERRRRARQERLRQKQEEESLGQ- MOUSE6_PE407 ISOFORMIN ---------------------------------------------------------------MLSGSGSQGRRCLATLSQIAYQRNDDD-EEEAARERRRRARQERLRQKQEEESLGQ- MOUSE6_PE412 ENSMUSG00000029761 -------------------------------------------------------MDDFERRRELRRQ--KREEMRLEAERIAYQRNDDD-EEEAARERRRRARQERLRQKQEEESLGQ- ORNAN10_9_PE10 ENSOANG00000005001 --------------------------------------------------------------------------------RLAYQRNDDD-EEEAARERRRRARQERLRQREEEDSSSQ- ORNAN10_9_PE11 ISOFORMIN ------------------------------------------------------------------------------------------------------------------------ PANTR7_143_PE10 ENSPTRG00000019721 -------------------------------------------------------MDDFERRR--ELRRQKREEMRLEAERIAYQRNDDD-EEEAARERRRRARQERLRQKQEEESLGQ- PANTR7_143_PE11 ISOFORMIN -------------------------------------------------------MDDFERRR--ELRRQKREEMRLEAERIAYQRNDDD-EEEAARERRRRARQERLRQKQEEESLGQ- PANTR7_143_PE12 ISOFORMIN QAQTFVTGTDQRVNTKGEHGSILHRAFQPQITWPLRGPGPRPDRPAWPGLRISLPRRPFPTADMLGGSGSHGRRSLAALSQIAYQRNDDD-EEEAARERRRRARQERLRQKQEEESLGQ- PIG18_14_PE9 NOISO --------------------------------------------------------------------------MRLEAERIAYQRNDDD-EEEAARERRRRARQERLRQKQEEESLGQ- POEGU1A_72_PE7 NOISO -------------------------------------------------------MDDFERRREL--RRQKREEMRLEAERLSYQRNDDD-DEEAARERRRRARQERLRQKEEGDLSGE- PONPY7_137_PE7 ENSPPYG00000018020 -------------------------------------------------------MDDFERRR--ELRRQKREEMRLEAERIAYQRNDDD-EEEAARERRRRARQERLRQKQEEESLGQ- PONPY7_137_PE8 ISOFORMIN ---------------------------------------------------------------MLGGSGSHGRRSLAALSQIAYQRNDDD-EEEAARERRRRARQERLRQKQEEESLGQ- PTEVA9791_PE1 NOISO ---------------------------------------------------------------------------------IAYQRNDDD-EEEAARERRRRARQERLRQKQEEESFGQ- RABIT7_14_PE10 ISOFORMIN ------------------------------------------------------------------------------------------------------------------------ RABIT7_14_PE8 ISOFORMIN --------------------------------------------------------------------------MRLEAERIAYQRNDDD-EEEAARERRRRARQERLRQKQEEESLGQ- RABIT7_14_PE9 ENSOCUG00000008127 -------------------------------------------------------MDDFERRREL--RRQKREEMRLEAERIAYQRNDDD-EEEAARERRRRARQERLRQKQEEESLGQ- RAT4_PE477 ENSRNOG00000010233 ---------------------------------------------------------------MLSRSGSQGRRCLATLSQIAYQRNDDD-EEEAARERRRRARQERLRQKQEEESLGQ- SORARGS_7223_PE1 NOISO -------------------------------------------------------MDDFERRREL--RRQKREEMRLEAERIAYQRNDDD-EEEAARERRRRARQERLRQKQEEDSLGQV TARSYGS_2912_PE1 NOISO -------------------------------------------------------MDDFERRREL--RRQKREEMRLEAEXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXX- TETNG19_PE282 ENSTNIG00000018525 --------------------------------------------------------MDFERRREL--RRQKREEMRLEAERLARTE--DD-EEEAARERRRRARQERLMNKEMEEPSAQA TUPGBGS_1886_PE1 NOISO -------------------------------------------------------MDDFERRR--ELRRQKREEMRLEAERIAYQRNDDD-EEEAARERRRRARQERLRQKQEEESLGQ- TURTRGS_1100_PE1 NOISO ---------------------------------------------------------------------------------IAYQRNDDD-EEEAARERRRRARQERLRQKQEEESLGQ- XENTR24_3_PE12 NOISO ------------------------------------------------------------------------------------------------------------------------ MATCH CONSENSUS ???????????????????????????????????????????????????????????????????????????????????YQRNDDD?EEEAARERRRRARQERLRQK?E????G??

AILMEGL193619_1_PE3 NOISO ---VTDQ-VEVNAQNSVADEEVKPSS-SHT-QAEGDDEAALLERLARREERRQKRLQEALERQREFDPTVT--DAGVSLPSRRTQNDAAADSEAAEKEEKSERRQERYEVEETEIVTKSY ANOCA90_1_PE4 NOISO ---GTEK-TEVNAQNNIGDEETKSTTTVRNTQGDGDDDAVFLERMARREERRQKRLQEALERQKEFDPTIT--DESLSLVNRKVMNNFEE-NETPDKEEKVETQRRRYEVEETGTITKSY BOVIN4_107_PE3 ENSBTAG00000013953 ---VTDQ-VEVNTQNSVPDEEVKTTT-TNT-QAEGDDEAALLERLARREERRQKRLQEALERQKEFDPTIT--DASLSLSSRRMQNDTTD-NETAEKEGRSESRQERQELEETEIVTKSH CALJA8_118_PE4 ENSCJAG00000012295 ---VTDQ-VEVNAQNSVPNEEAKTAT-TNT-QVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTIT--DASLSLPSRRMQNDTAE-NETAEKEEKSESRQERYEIEETETITKSY CALJA8_118_PE5 ISOFORMIN ---VTDQ-VEVNAQNSVPNEEAKTAT-TNT-QVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTIT--DASLSLPSRRMQNDTAE-NETAEKEEKSESRQERYEIEETETITKSY CALJA8_118_PE6 ISOFORMIN ---VTDQ-VEVNAQNSVPNEEAKTAT-TNT-QVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTIT--DASLSLPSRRMQNDTAE-NETAEKEEKSESRQERYEIEETETITKSY CALJA8_118_PE7 ISOFORMIN ---VTDQ-VEVNAQNSVPNEEAKTAT-TNT-QVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTIT--DASLSLPSRRMQNDTAE-NETAEKEEKSESRQERYEIEETETITKSY CALJA8_118_PE8 ISOFORMIN ---VTDQ-VEVNAQNSVPNEEAKTAT-TNT-QVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTIT--DASLSLPSRRMQNDTAE-NETAEKEEKSESRQERYEIEETETITKSY CALJA8_118_PE9 ISOFORMIN ---VTDQ-VEVNAQNSVPNEEAKTAT-TNT-QVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTIT--DASLSLPSRRMQNDTAE-NETAEKEEKSESRQERYEIEETETITKSY CANFA16_17_PE5 NOISO ---VTDQ-VEVNAQNSVADEEGKSG-A-TPAPVEGDDEAALLERLARREERRQKRLQEALERQRELDPTVTVTDASASPASRRLQNNAAP-GEAAEKEEKSEPGQEGYAIAGPQVATKPQ CAVPO10_14_PE12 ENSCPOG00000023504 ---VTDQ-LEVHAQNSVPDEEAKPTT-TNT-QAEGDEEAALLERLARREERRQKRLQEALERQKEFDPTIA--DSSLSQPSQRMQNNLVE-NETAEKEEKRESRQERYEMEETEIVTKSY CAVPO10_14_PE13 ISOFORMIN ---VTDQ-LEVHAQNSVPDEEAKPTT-TNT-QAEGDEEAALLERLARREERRQKRLQEALERQKEFDPTIA--DSSLSQPSQRMQNNLVE-NETAEKEEKRESRQERYEMEETEIVTKSY CHICK1_PE1105 ISOFORMIN ---VTEK-SEVNAQNSVAEEETKRS---------TDDEAALLERLARREERRQKRLQEALERQKEFDPTIT--DGSLSVPSRREVNNVEE-NETTGKEEKVETRQGRCEIEETETVTKSY CHICK1_PE1106 ISOFORMIN ---VTEK-SEVNAQNSVAEEETKRS---------TDDEAALLERLARREERRQKRLQEALERQKEFDPTIT--DGSLSVPSRREVNNVEE-NETTGKEEKVETRQGRCEIEETETVTKSY CHICK1_PE1107 ISOFORMIN ---VTEK-SEVNAQNSVAEEETKRS---------TDDEAALLERLARREERRQKRLQEALERQKEFDPTIT--DGSLSVPSRREVNNVEE-NETTGKEEKVETRQGRCEIEETETVTKSY CHICK1_PE1108 ENSGALG00000013071 ---VTEK-SEVNAQNSVAEEETKRS---------TDDEAALLERLARREERRQKRLQEALERQKEFDPTIT--DGSLSVPSRREVNNVEE-NETTGKEEKVETRQGRCEIEETETVTKSY CHOHOGS_2782_PE1 NOISO ---VTDQ-VEVNAQNSVPEEETKATT-TNT-QVEGDDEAALLERLARREERRQKRLQEALERQKEFDPTIT--DASLSLPGRGMQNNTAE-NETAEKDEKSESRQERYEIEETEIVTRSY ECHTEGS_2967_PE1 NOISO ---VTDQ-VEVNAQNSVSAEEAKTSA-PNP-QGEGDEEAALLERLARREERRQKRLQEALERQKEFDPTIT--DAGGSLPSR-MENNTAE-NEAAEKEEKSESRQESYEIEEVQIITKAY FELCAGS_1637_PE1 NOISO ---VTDQ-VEVNAQNXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--X-XXXXXXXX-XXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXX FUGRU2_4_PE79 ENSTRUG00000016845 -----TEVIDTNSEGSADMKRSKQT--VTLQRVRGRLRPCLADRLAKREERRQKRMKEAVERQKENDVG-E--TNGTENDSSLQQEDKDEEDEPVGKE--------------------DD FUGRU2_4_PE80 ISOFORMIN -----TEVIDTNRYGVQITK-----------TNEGSADMSLADRLAKREERRQKRMKEAVERQKENDVG-E--TNGTENDSSLQQEDKDEEDEPVEE----------------------- GASACGROUPXIX_6_PE49 NOISO -----TDGIDTNSVETTGGEG-------------ADDDQALLERLAKREERRQKRMKEALERQKDLDQSAS--TNGTELPPSLRQRDTT----PIPT----------------------- GORGO7_137_PE8 ENSGGOG00000009728 ---VTDQ-VEVNAQNSVPDEEAKTTT-TNT-QVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTIT--DASLSLPSRRMQNDTAE-NETAEKEEKSESRQERYEIEETETVTKSY GORGO7_137_PE9 ISOFORMIN ---VTDQ-VEVNAQNSVPDEEAKTTT-TNT-QVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTIT--DASLSLPSRRMQNDTAE-NETAEKEEKSESRQERYEIEETETVTKSY HORSE4_93_PE3 NOISO ---VTDQ-VEVNAQNSVPDEEVKTTT-TNT-QVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTIT--DASLSPPSRRMQNNTGE-NETAEKEEKSESRRERYEIEETETVTKSY HS7_PE3870 ISOFORMIN ---VTDQ-VEVNAQNSVPDEEAKTTT-TNT-QVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTIT--DASLSLPSRRMQNDTAE-NETTEKEEKSESRQERYEIEETETVTKSY HS7_PE3871 ISOFORMIN ---VTDQ-VEVNAQNSVPDEEAKTTT-TNT-QVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTIT--DASLSLPSRRMQNDTAE-NETTEKEEKSESRQERYEIEETETVTKSY HS7_PE3872 ISOFORMIN ---VTDQ-VEVNAQNSVPDEEAKTTT-TNT-QVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTIT--DASLSLPSRRMQNDTAE-NETTEKEEKSESRQERYEIEETETVTKSY HS7_PE3875 ENSG00000122786 ---VTDQ-VEVNAQNSVPDEEAKTTT-TNT-QVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTIT--DASLSLPSRRMQNDTAE-NETTEKEEKSESRQERYEIEETETVTKSY HS7_PE3876 ISOFORMIN ---VTDQ-VEVNAQNSVPDEEAKTTT-TNT-QVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTIT--DASLSLPSRRMQNDTAE-NETTEKEEKSESRQERYEIEETETVTKSY HS7_PE3879 ISOFORMIN ---VTDQ-VEVNAQNSVPDEEAKTTT-TNT-QVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTIT--DASLSLPSRRMQNDTAE-NETTEKEEKSESRQERYEIEETETVTKSY HS7_PE3880 ISOFORMIN ---VTDQ-VEVNAQNSVPDEEAKTTT-TNT-QVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTIT--DASLSLPSRRMQNDTAE-NETTEKEEKSESRQERYEIEETETVTKSY HS7_PE3881 ISOFORMIN ---VTDQ-VEVNAQNSVPDEEAKTTT-TNT-QVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTIT--DASLSLPSRRMQNDTAE-NETTEKEEKSESRQERYEIEETETVTKSY HS7_PE3882 ISOFORMIN ---VTDQ-VEVNAQNSVPDEEAKTTT-TNT-QVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTIT--DASLSLPSRRMQNDTAE-NETTEKEEKSESRQERYEIEETETVTKSY HS7_PE3883 ISOFORMIN ---VTDQ-VEVNAQNSVPDEEAKTTT-TNT-QVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTIT--DASLSLPSRRMQNDTAE-NETTEKEEKSESRQERYEIEETETVTKSY LOXAF101_1_PE8 NOISO ---VTDQ-VEVNAQNSVPAEEAKTTT-PNT-QGEGDDEAALLERLARREERRQKRLQEALERQKEFDPTIT--DAGLSLPSRRMENNTAE-NETAEKEEKSESRQERYEIEETEIITKSY MACEUGS_3523_PE1 NOISO ---ATEK-VEVNAQNSVGDEETKST-TISNTQVEGSDDAAFLERLARREERRQKRLQEALERQKEFDPTIT--DESLSLSNRRAQNDAAE-NETSEKEEKSEIRQERYKVEETETVTKSY MACMU3_178_PE13 ENSMMUG00000006527 ---VTDQ-VEVNAQNSVPDEEAKTTT-TNT-QVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTVT--DASLSLPSKRMQNDTAE-NETAEKEEKRESRQERYEIEETETVTKSY MACMU3_178_PE14 ISOFORMIN ---VTDQ-VEVNAQNSVPDEEAKTTT-TNT-QVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTVT--DASLSLPSKRMQNDTAE-NETAEKEEKRESRQERYEIEETETVTKSY MACMU3_178_PE15 ISOFORMIN ---VTDQ-VEVNAQNSVPDEEAKTTT-TNT-QVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTVT--DASLSLPSKRMQNDTAE-NETAEKEEKRESRQERYEIEETETVTKSY MACMU3_178_PE16 ISOFORMIN ---VTDQ-VEVNAQNSVPDEEAKTTT-TNT-QVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTVT--DASLSLPSKRMQNDTAE-NETAEKEEKRESRQERYEIEETETVTKSY MICMUGS_3600_PE2 NOISO DSEVMPX-XXXXXXXXVPDEEAKTST-TNA-QVEGDDEAALLERLARREERRQKRLQEALERQKEFDPTVT--DASLSLPSRRMQNDTAE-NETAEKEEKNESRQERYEIEETQIVTKSY MONDO8_203_PE5 ENSMODG00000014124 ---VTEK-VEVNAQNSVGDEETKTS-TTSNTQVEEGDDAAFLERLARREERRQKRLQEALERQKEFDPTIT--DESLSLTNRRAQNDAAE-NETSEKEEKSEIRRERYQVEETETVTKSY MONDO8_203_PE6 ISOFORMIN ---------------SVGDEETKTS-TTSNTQVEEGDDAAFLERLARREERRQKRLQEALERQKEFDPTIT--DESLSLTNRRAQNDAAE-NETSEKEEKSEIRRERYQVEETETV---- MONDO8_203_PE7 ISOFORMIN ---------------SVGDEETKTS-TTSNTQVEEGDDAAFLERLARREERRQKRLQEALERQKEFDPTIT--DESLSLTNRRAQNDAAE-NETSEKEEKSEIRRERYQVEETET----- MONDO8_203_PE8 ISOFORMIN ---------------SVGDEETKTS-TTSNTQVEEGDDAAFLERLARREERRQKRLQEALERQKEFDPTIT--DESLSLTNRRAQNDAAE-NETSEKEEKSEIRRERYQVEETE------ MOUSE6_PE402 ISOFORMIN ---VTDQ-VEAHVQNSVPDEESKPAS-SNT-QVEGDEEAALLERLARREERRQKRLQEALERQKEFDPTIT--DGSLSGPSRRMQNDSAE-NETAEGEEKRESRSGRYEVEETEVVIKSY MOUSE6_PE404 ISOFORMIN ---VTDQ-VEAHVQNSVPDEESKPAS-SNT-QVEGDEEAALLERLARREERRQKRLQEALERQKEFDPTIT--DGSLSGPSRRMQNDSAE-NETAEGEEKRESRSGRYEVEETEVVIKSY MOUSE6_PE405 ISOFORMIN ---VTDQ-VEAHVQNSVPDEESKPAS-SNT-QVEGDEEAALLERLARREERRQKRLQEALERQKEFDPTIT--DGSLSGPSRRMQNDSAE-NETAEGEEKRESRSGRYEVEETEVVIKSY MOUSE6_PE406 ISOFORMIN ---VTDQ-VEAHVQNSVPDEESKPAS-SNT-QVEGDEEAALLERLARREERRQKRLQEALERQKEFDPTIT--DGSLSGPSRRMQNDSAE-NETAEGEEKRESRSGRYEVEETEVVIKSY MOUSE6_PE407 ISOFORMIN ---VTDQ-VEAHVQNSVPDEESKPAS-SNT-QVEGDEEAALLERLARREERRQKRLQEALERQKEFDPTIT--DGSLSGPSRRMQNDSAE-NETAEGEEKRESRSGRYEVEETEVVIKSY MOUSE6_PE412 ENSMUSG00000029761 ---VTDQ-VEAHVQNSVPDEESKPAS-SNT-QVEGDEEAALLERLARREERRQKRLQEALERQKEFDPTIT--DGSLSGPSRRMQNDSAE-NETAEGEEKRESRSGRYEVEETEVVIKSY ORNAN10_9_PE10 ENSOANG00000005001 ---GTEKTAEVNAQNSVADEEAKTAP--SPSTTDESDDAAFLERLARREERRQKRLQEALERQKEFDPTVT--DDGLSVPSERQANDTGK-DEAAGDEDKAETRRARYEIQETETVTKSY ORNAN10_9_PE11 ISOFORMIN ------------------------------------------------------------------------------------------------------------------------ PANTR7_143_PE10 ENSPTRG00000019721 ---VTDQ-VEVNAQNSVPDEEAKTTT-ANT-QVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTIT--DASLSLPSRRMQNDTAE-NETAEKEEKSESRQERYEIEETETVTKSY PANTR7_143_PE11 ISOFORMIN ---VTDQ-VEVNAQNSVPDEEAKTTT-ANT-QVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTIT--DASLSLPSRRMQNDTAE-NETAEKEEKSESRQERYEIEETETVTKSY PANTR7_143_PE12 ISOFORMIN ---VTDQ-VEVNAQNSVPDEEAKTTT-ANT-QVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTIT--DASLSLPSRRMQNDTAE-NETAEKEEKSESRQERYEIEETETVTKSY PIG18_14_PE9 NOISO ---VTDQ-VEVNTQNSVPDEQVKTTT-TNT-QMEADDEAALLERLARREERRQKRLQEALERQKEFDPTIA--DASSSPPSRRMQNSTAE-DETAEKDEKSESRQERYEIEETEVVTKSY POEGU1A_72_PE7 NOISO ---VTEK-SEVNAQNSVAGEESKRS---------TDDEAALLERLARREERRQKRLQEALERQKEFDPTIT--DGSLSVPSRREVNNVEE-NESTGKEEKAETRRGRYEIEETETVTKSY PONPY7_137_PE7 ENSPPYG00000018020 ---VTDQ-VEVNAQNSVPDEEAKTTT-TNT-QVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTIT--DSSLSLPNRRMQNDTAE-NETAEKEEKSESCQERYEIEETETVTKSY PONPY7_137_PE8 ISOFORMIN ---VTDQ-VEVNAQNSVPDEEAKTTT-TNT-QVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTIT--DSSLSLPNRRMQNDTAE-NETAEKEEKSESCQERYEIEETETVTKSY PTEVA9791_PE1 NOISO ---VTDQ-VEVNAQNXXXXXXXXXX-X-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXX RABIT7_14_PE10 ISOFORMIN ------------------------------------------------------------------------------------------------------------------------ RABIT7_14_PE8 ISOFORMIN ---VADQ-VEVHAQNSVSNEDSKPS-T-TSTQVEGDDEAALLERLARREERRQKRLQEALERQKEFDPTVTD--ASASLPSRRMPNDTAE-NETAEKEAKAESRRERYETEETETITKSE RABIT7_14_PE9 ENSOCUG00000008127 ---VADQ-VEVHAQNSVSNEDSKPS-T-TSTQVEGDDEAALLERLARREERRQKRLQEALERQKEFDPTVTD--ASASLPSRRMPNDTAE-NETAEKEAKAESRRERYETEETETITKSE RAT4_PE477 ENSRNOG00000010233 ---VTDQ-VEAHVQNSVPDEESKPAT-ANA-QVEGDEEAALLERLARREERRQKRLQEALERQKEFDPTIT--DGSLSVPSRRMQNNSAE-NETAEGEEKGESRSGRYEMEETEVVITSY SORARGS_7223_PE1 NOISO ---TTDQ-VEVNAQNSVSNEEVKTTS-THTSVLEGDDEAAFQERLARREERRQKRLQEALERQKELDPTIT--DGGSSLLSRRATNSTAD-ADGAEKEEKRESRQERYELDGA--GSKSY TARSYGS_2912_PE1 NOISO ---XXXX-XXXXXXXXVPDEETKTA-T-TNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTMA--DASVSLPSRRVQNDMAE-DETAEREEKTESCQGRYEIEERETVTKSY TETNG19_PE282 ENSTNIG00000018525 DGALAAN-----SHGAS--EDQNISSQRSFTCLEVTDEQALLERMAKREERRQRRMKEALERQRQQEPEGG-----ESVAA--------------EEDRPSSRRRARYRDRLKRILHDGA TUPGBGS_1886_PE1 NOISO ---VTDQ-VELNAQNSVPDEEAKTTT-TNT-QAEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTVT--DASLSLPSRRTQNDTAE-NDTAEKEEKRESRQERYEIEETEIVTRSY TURTRGS_1100_PE1 NOISO ---VTDQ-VEVNTQNSVPDEEVKTTT-TDT-QVEADDEAALLERLARREERRQKRLQEALERQKDSDPTIA--DASLLLPSRRMQNNTAE-NEMAEKEEKSESRRERYEIEETETVTKSH XENTR24_3_PE12 NOISO ------------------------------------------------------------------------------------------------------------------------ MATCH CONSENSUS ????T????E???QNSV??EE?K??????????E?D??AA?LERLARREERRQKRLQEALERQKEFDPT?T??D?S?S????R??N???E??E??E?EEK?E?R??RY??EETE????S?

AILMEGL193619_1_PE3 NOISO QKNDWRDAEEKKQEEKEKE----EEEEEKPKQGSLEENQVEVTAEGGTP----DTAAVPLETGQLSAEEPRTEEEPERGSDE-AAHNGRMETEG-------------------------- ANOCA90_1_PE4 NOISO QRNNLRQEEEDEKKDEE---DKEETEEDKPKERAIEDNQVEVTLEKKT-DTEEEAVVLEIKYPEVNAEEGKKDEEEDDEAE-----KEKIEEKERAEREEMERAKAEEQR-KAEEEKERL BOVIN4_107_PE3 ENSBTAG00000013953 QKNDWMEAEEKKKEEKEKE----EEEEEKPKPGSIEENQL-------------------------------------------------------------------------------- CALJA8_118_PE4 ENSCJAG00000012295 QKNDWRNADENKKDAKEKE----EEEEEKSKRGSIGENQVEGMVEEKTTASQEETVGMSLKNGQISSEEPQPEEEREQGSDE-IPHHEKMEEED-------------------------- CALJA8_118_PE5 ISOFORMIN QKNDWRNADENKKDAKEKE----EEEEEKSKRGSIGENQVE------------------------------------------------------------------------------- CALJA8_118_PE6 ISOFORMIN QKNDWRNADENKKDAKEKE----EEEEEKSKRGSIGENQ--------------------------------------------------------------------------------- CALJA8_118_PE7 ISOFORMIN QKNDWRNADENKKDAKEKE----EEEEEKSKRGSIGENQVE------------------------------------------------------------------------------- CALJA8_118_PE8 ISOFORMIN QKNDWRNADENKKDAKEKE----EEEEEKSKRGSIGENQVEGMVEEKTTASQEETVGMSLKNGQISSEEPQPEEEREQGSDE-IPHHEKMEEED-------------------------- CALJA8_118_PE9 ISOFORMIN QKNDWRNADENKKDAKEKE----EEEEEKSKRGSIGENQI-------------------------------------------------------------------------------- CANFA16_17_PE5 NOISO QKNDCRDTEEKQQEEEEEGKAEEEEEEEKAKPGSREENQVEAAAAGAGPEAA----ALRWGTGQPGAEEPGPEERGARGPA--EA----------------------------------- CAVPO10_14_PE12 ENSCPOG00000023504 QKNDWQDAEDRKREEKEKE----EEEAEKPKQGSIGENQVEGLVEEKTAEIQEETVVTVMKNGQISAEESKPEEERDRGSGE-ASHNEKMEEEE-------------------------- CAVPO10_14_PE13 ISOFORMIN QKNDWQDEESKPEEER------------------------------------------------------------DRGSGE-ASHNEKM------------------------------ CHICK1_PE1105 ISOFORMIN QRNNWRQDGEEEGK--KEEKDS---EEEKPKEVPTEENQVDVAVEKSTDKEE----VVETKTLAVNAENDTNAMLEGEQSITDAADKEKEEAE--KEREKLE-----------AEEKERL CHICK1_PE1106 ISOFORMIN QRNNWRQDGEEEGK--KEEKDS---EEEKPKEVPTEENQVDVAVEKSTDKEE----VVETKTLAVNAENDTNAMLEGEQSITDAADKEKEEAE--KEREKLE-----------AEEKERL CHICK1_PE1107 ISOFORMIN QRNNWRQDGEEEGK--KEEKDS---EEEKPKEVPTEENQ--------------------------------------------------------------------------------- CHICK1_PE1108 ENSGALG00000013071 QRNNWRQDGEEEGK--KEEKDS---EEEKPKEVPTEENQVDVAVEKSTDKEE----VVETKTLAVNAENDTNAMLEGEQSITDAADKEKEEAE--KEREKLE-----------AEEKERL CHOHOGS_2782_PE1 NOISO QKNDWRDAEEKKKEEKEKE----EEEEEKPKQRSIEENQVEVMVKEETTETQEETVAMPLKNGQISAEEPKVEEERKQDSDE-GALNEKVEEKA-------------------------- ECHTEGS_2967_PE1 NOISO QKNDWRDAAGENKKE---EK-E-EGEEEKPKQGSVDDHQVEVMVEERRREGTAEAVGTPLKNGHLSAEESTPEEGRDQESEE-GAHQEKVEAIE-------------------------- FELCAGS_1637_PE1 NOISO XXXXXRDTEEKKKE----EKEKEEEEEEKPKQGSPEENQVEGPVEDRTTET----SAMPLTTGQTSAEEPQTEGEGEQGSE--EAAHRER------------------------------ FUGRU2_4_PE79 ENSTRUG00000016845 DANSCRTAEEDKGEEDKVQK-------------------------------------LELINMTD----KEEEEERLRKE---EEDRLKIEEEEK------------------------- FUGRU2_4_PE80 ISOFORMIN ------------------------------------------------------------------------EEERLRKE---EEDRLKIEEEEK------------------------- GASACGROUPXIX_6_PE49 NOISO -----------AGEKEK-----------------------------------------------------------------------------K------------------------- GORGO7_137_PE8 ENSGGOG00000009728 QKNDWRDAEENKKEDKEKE----E-EEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDE-IPHHEKMEEED-------------------------- GORGO7_137_PE9 ISOFORMIN QKNDWRD----------------------PKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDE-IPHHEKMEEED-------------------------- HORSE4_93_PE3 NOISO QRNDWRDAEEKKKEEKEKE----EEEEEKPKQGSIEENQ--------------------------------------------------------------------------------- HS7_PE3870 ISOFORMIN QKNDWRDAEENKKEDKEKE----EEEEEKPKRGSIGENQI-------------------------------------------------------------------------------- HS7_PE3871 ISOFORMIN QKNDWRDAEENKKEDKEKE----EEEEEKPKRGSIGENQI-------------------------------------------------------------------------------- HS7_PE3872 ISOFORMIN QKNDWRDAEENKKEDKEKE----EEEEEKPKRGSIGENQ--------------------------------------------------------------------------------- HS7_PE3875 ENSG00000122786 QKNDWRDAEENKKEDKEKE----EEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDE-ISHHEKMEEED-------------------------- HS7_PE3876 ISOFORMIN QKNDWRDAEENKKEDKEKE----EEEEEKPKRGSIGENQI-------------------------------------------------------------------------------- HS7_PE3879 ISOFORMIN QKNDWRDAEENKKEDKEKE----EEEEEKPKRGSIGENQ--------------------------------------------------------------------------------- HS7_PE3880 ISOFORMIN QKNDWRDAEENKKEDKEKE----EEEEEKPKRGSIGENQ--------------------------------------------------------------------------------- HS7_PE3881 ISOFORMIN QKNDWRDAEENKKEDKEKE----EEEEEKPKRGSIGENQGE------------------------------------------------------------------------------- HS7_PE3882 ISOFORMIN QKNDWRDAEENKKEDKEKE----EEEEEKPKRGSIGENQ--------------------------------------------------------------------------------- HS7_PE3883 ISOFORMIN QKNDWRDAEENKKEDKEKE----EEEEEKPKRGSIGENQGE------------------------------------------------------------------------------- LOXAF101_1_PE8 NOISO QKNDWRDAQKMEEEERKR------------------------------------------------------------------------------------------------------ MACEUGS_3523_PE1 NOISO QKNDWREPEEDKKEGKEK------EEEEKPKQRIIEENQVEVMVEKKT-ETQEEKVVIELKNGQVCAEEPKIEERTVDTDE--FTSNEKVEEQG------QERAEAEKLRLEAEAEKLRL MACMU3_178_PE13 ENSMMUG00000006527 QKNDWRDAEENKKEDKEKE----EEEEEKPKRGSIGENQ--------------------------------------------------------------------------------- MACMU3_178_PE14 ISOFORMIN QKNDWRDAEENKKEDKEKE----EEEEEKPKRGSIGENQ--------------------------------------------------------------------------------- MACMU3_178_PE15 ISOFORMIN QKNDWRDAEENKKEDKEKE----EEEEEKPKRGSIGENQGE------------------------------------------------------------------------------- MACMU3_178_PE16 ISOFORMIN QKNDWRDAEENKKEDKEKE----EEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDE-IPHHEKMEEED-------------------------- MICMUGS_3600_PE2 NOISO QKNDWRDAEENKKEK-EKEE-E-EEEDEKPKQRSIGDNQVEAMVEENTAESQEETVVMSLKNGQISAEEPKLEEEREQGSDE-IPHNEKTEDED-------------------------- MONDO8_203_PE5 ENSMODG00000014124 QKNDWREPEEDKKEEKKK-----EEEEEKPKQRIIEENQVEAMVERKT-ETQEEEVVIQLKNGQIYAEEPKLEENRTDRDE--VTGNEKAEEQD------Q--AEAEKLRLEAEAEKLRL MONDO8_203_PE6 ISOFORMIN ------------------------------------------------------------------------------------TGNEKAEEQD------Q--AEAEKLRLEAEAEKLRL MONDO8_203_PE7 ISOFORMIN ---------------------------------------VEAMVERKT-ETQEEEVVIQLKNGQIYAEEPKLEENRTDRDE--------------------------------------- MONDO8_203_PE8 ISOFORMIN --------------------------------------------------------------------TPKLEENRTDRDE--VTGNEKAEEQD------Q--AEAEKLRGG-------- MOUSE6_PE402 ISOFORMIN QKNSYQDAEDKKKEEKEE------EEQEKLKGGSLGENQI-------------------------------------------------------------------------------- MOUSE6_PE404 ISOFORMIN QKNSYQDAEDKKKEEKEE------EEQEKLKGGSLGENQVEKMVEEKTPEIQEEAVLMVLENGQVSAEESKIEGDGEQDMEE-IARRKKMGEEE-------------------------- MOUSE6_PE405 ISOFORMIN QKNSYQDAEDKKKEEKEE------EEQEKLKGGSLGENQI-------------------------------------------------------------------------------- MOUSE6_PE406 ISOFORMIN QKNSYQDAEDKKKEEKEE------EEQEKLKGGSLGENQ--------------------------------------------------------------------------------- MOUSE6_PE407 ISOFORMIN QKNSYQDAEDKKKEEKEE------EEQEKLKGGSLGENQEEEKGVKGQAQRQK------------------------------------------------------------------- MOUSE6_PE412 ENSMUSG00000029761 QKNSYQDAEDKKKEEKEE------EEQEKLKGGSLGENQVEKMVEEKTPEIQEEAVLMVLENGQVSAEESKIEGDGEQDMEE-IARRKKMGEEE-------------------------- ORNAN10_9_PE10 ENSOANG00000005001 QRNEWRETQ-----------------DGQPKQRILEGNQVEVTIGRKTVETREETAVVELKNGQVGVEESKLGKEEEAEEATEVVDHE-------------------------------- ORNAN10_9_PE11 ISOFORMIN -------------------------------------------------------------------KERKRGKEEEAEEATEVVDHE-------------------------------- PANTR7_143_PE10 ENSPTRG00000019721 QKNDWRDAEENKKEDKEKE----EEEEEKPKRGSIGENQVEVMVEEKTTASQEETVVMSLKNGQISSEEPKQEEEREQGSDE-IPHHEKMEEED-------------------------- PANTR7_143_PE11 ISOFORMIN QKNDWRDAEENKKEDKEKE----EEEEEKPKRGSIGENQI-------------------------------------------------------------------------------- PANTR7_143_PE12 ISOFORMIN QKNDWRDAEENKKEDKEKE----EEEEEKPKRGSIGENQGE------------------------------------------------------------------------------- PIG18_14_PE9 NOISO QKNDWRDAEEQKKEEKEKE----EEEEEKPNQGSIEENQE-------------------------------------------------------------------------------- POEGU1A_72_PE7 NOISO QRNNWRQDGEEEGK--KEEKDKEEVQEEKPKELPIEENQVDVAAEKSTDKEE----AVTVNAEEHTAENDTNAVPEGTQSVTDAVDKEKLRDEEKAEEERKE-----------AEERERL PONPY7_137_PE7 ENSPPYG00000018020 QKNDWRDAEENKKEDKEKE----EEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDE-IPHHEKMEEED-------------------------- PONPY7_137_PE8 ISOFORMIN QKNDWRDAEENKKEDKEKE----EEEEEKPKRGSIGENQ--------------------------------------------------------------------------------- PTEVA9791_PE1 NOISO XKNDWRVAEENKKDEK----EKEGEEEEKPKPGSIKENQVEVVVEEKTTEPQEETMGVALKNEQMGADRPHTEEREQGSEE--MISDEKMEE-E-------------------------- RABIT7_14_PE10 ISOFORMIN ----------M------------------------------------------------------------------------------------------------------------- RABIT7_14_PE8 ISOFORMIN QKNDWRDAEDK------------------------------------------------------------------------------------------------------------- RABIT7_14_PE9 ENSOCUG00000008127 QKNDWRDAEDK------------------------------------------------------------------------------------------------------------- RAT4_PE477 ENSRNOG00000010233 QKNSYQDAEDKKKEEKEE-----EEEEEKLKGGNLGENQ--------------------------------------------------------------------------------- SORARGS_7223_PE1 NOISO QKNDWRDAEAPKKEGKEKEE-EEEEEEAKPKPGSMEDNQVEVTAGEKPAESQEETGGMSLNNGQVSAEEPGQA--------E-VTGSAKVEEEE-------------------------- TARSYGS_2912_PE1 NOISO QKNDWRGADANKKEEKEK-----EEAEEKPEQGSTGEDQVEAMVEEKT-ESREETVVMSLENGLISAEEPKLEAERGQSSD--EI-AHDEEE-D-------------------------- TETNG19_PE282 ENSTNIG00000018525 QVSHR-------------------------------------------------------QRGPC-------------------FH---------------------------------- TUPGBGS_1886_PE1 NOISO QKNDWRDGEEIKKEEKEE-----EEEEGKPKQGNIGENQVEMMVEEKTTESQEETVGMPLKNGHVSAEEPHPEEERGPGSDE-SAHNEKREEEE-------------------------- TURTRGS_1100_PE1 NOISO QKNDWMDAEEKKEEEKEKEE-E-EEEEEKPKQGSIEENQVEVVAEEKAAETQEETVM-SLKNGQIGTDEPKTEEEREKGSHE-IPHNEKMEQEA-------------------------- XENTR24_3_PE12 NOISO ------------------------------------------------------------------------------------------------------------------------ MATCH CONSENSUS Q?N???????????????????????????????????Q?????????????????????????????????????????????????????????????????????????????????

AILMEGL193619_1_PE3 NOISO ---------------REQAEADRARLEA-----EERERIKA---EQEQRVAEEQARREAEERAA------A-QERERREAAERERVEQERRA---------------------------- ANOCA90_1_PE4 NOISO EA-------------EKRAAEEKERLEAEERVRKEQERIKA---EEERKAAEEKKRIEEEEKRA------A-QEKERQEAEE--------------RERIKAAE---AKKAAEERERAKE BOVIN4_107_PE3 ENSBTAG00000013953 ------------------------------------------------------------------------------------------------------------------------ CALJA8_118_PE4 ENSCJAG00000012295 ---------------KERAEAERVRLE-------AEERERI-KAEQDKKIADERARIEAEEKAA------A-QERERREAEERERMREEEKRAAEERQ-RVKEEEKRAAEERQ---RVKE CALJA8_118_PE5 ISOFORMIN ------------------------------------------------------------------------------------------------------------------------ CALJA8_118_PE6 ISOFORMIN ------------------------------------------------------------------------------------------------------------------------ CALJA8_118_PE7 ISOFORMIN ------------------------------------------------------------------------------------------------------------------------ CALJA8_118_PE8 ISOFORMIN ---------------KERAEAERVRLEA-----EERERIKA---EQDKKIADERARIEAEEKAA------A-QEREKINFRQLSQRNRYKRRERKWLE-PLLKKK------S-------- CALJA8_118_PE9 ISOFORMIN ------------------------------------------------------------------------------------------------------------------------ CANFA16_17_PE5 NOISO ----------------------AARLEE-----EEGETTKA---EQERREAAEQAGREAEERAA------E-QERARREAAE--------------REKEREREKERERERERERERVAE CAVPO10_14_PE12 ENSCPOG00000023504 ---------------RERAEAERLRLE-------AEERERI-KAEQEKEIAQERARIEAEEKAA------A-QERERKEAEEREKTKEEERRRAEEER-RVEEERRAEEERRAEEERRAE CAVPO10_14_PE13 ISOFORMIN ------------------------------------------------------------------------------------------------------------------------ CHICK1_PE1105 ISOFORMIN KAEE-----------EKKAAEEKQKAEEEKKAAEERERAKA---EEEKRAAEERERAKAEEERK------AAEERERAKAEEERKAAEERAKAEEERKAAEERAKAEEERKAAEERAKAE CHICK1_PE1106 ISOFORMIN KAEE-----------EKKAAEEKQKAEEEKKAAEERERAKA---EEEKRAAEERERAKAEEERK------AAEERERAKAEEERKAAEERAKAEEERKAAEERAKAEEERKAAEERAKAE CHICK1_PE1107 ISOFORMIN ------------------------------------------------------------------------------------------------------------------------ CHICK1_PE1108 ENSGALG00000013071 KAEE-----------EKKAAEEKQKAEEEKKAAEERERAKA---EEEKRAAEERERAKAEEERK------AAEERERAKAEEERKAAEERAKAEEERKAAEERAKAEEERKAAEERAKAE CHOHOGS_2782_PE1 NOISO ---------------RERAEAERMRLEA-----EERERIKA---EQDKKIAEEKARIEAEEKAA------A-QERERREAEERERIKEEEKRAAEERQ-RIK------------------ ECHTEGS_2967_PE1 NOISO ---------------RERAEAERAKLEA-----EERERLQA---EQERKMAEERARVEAEAQAA------R-E-REQREREERERAEEEEKRAEE------------------------- FELCAGS_1637_PE1 NOISO ----------REREEKERAEAERARLEA-----EERERMKA---EEEQRVAEEKARIEAEERAA------A-QERERREAAE--------------------------------RERAKE FUGRU2_4_PE79 ENSTRUG00000016845 ---------------QKREMEEKLRKEE-------E--------EKKKREMEEKQKKEEEEKRKKEAKRKEEEENRRKEMEEKKKREEEERQKKRELEQKKK--------KEEEEKRK-- FUGRU2_4_PE80 ISOFORMIN ---------------QKREMEEKLRKEE-------E--------EKKKREMEEKQKKEEEEKRKKEAKRKEEEENRRKEMEEKKKREEEERQKKRELE---------------------- GASACGROUPXIX_6_PE49 NOISO ---------------TKRKM----RRSE-------Q--------IKE------------------NAA-------ATEEFEQPDRRTNEK------------------------------ GORGO7_137_PE8 ENSGGOG00000009728 ---------------KERAEAERARLE-------AEERERI-KAEQDKKIADERARIEAEEKAA------A-QERERREAEERERMREEEKRAAEERQ-RIKEEEKRAAEERQ---RIKE GORGO7_137_PE9 ISOFORMIN ---------------KERAEAERARLEA-----EERERIKA---EQDKKIADERARIEAEEKAA------A-QERERR------------------------------------------ HORSE4_93_PE3 NOISO ------------------------------------------------------------------------------------------------------------------------ HS7_PE3870 ISOFORMIN ------------------------------------------------------------------------------------------------------------------------ HS7_PE3871 ISOFORMIN ------------------------------------------------------------------------------------------------------------------------ HS7_PE3872 ISOFORMIN ------------------------------------------------------------------------------------------------------------------------ HS7_PE3875 ENSG00000122786 ---------------KERAEAERARLE-------AEERERI-KAEQDKKIADERARIEAEEKAA------A-QERERREAEERERMREEEKRAAEERQ-RIKEEEKRAAEERQ---RIKE HS7_PE3876 ISOFORMIN ------------------------------------------------------------------------------------------------------------------------ HS7_PE3879 ISOFORMIN ------------------------------------------------------------------------------------------------------------------------ HS7_PE3880 ISOFORMIN ------------------------------------------------------------------------------------------------------------------------ HS7_PE3881 ISOFORMIN ------------------------------------------------------------------------------------------------------------------------ HS7_PE3882 ISOFORMIN ------------------------------------------------------------------------------------------------------------------------ HS7_PE3883 ISOFORMIN ------------------------------------------------------------------------------------------------------------------------ LOXAF101_1_PE8 NOISO ------------------AEAE-------------------------------------------------------------------------------------------------- MACEUGS_3523_PE1 NOISO EAEAEKKVGGRGRETQVGAEAEKLRLEA-----EERERIKA---EQERRAEEERVRIEAEERLA------A-QEKERKEAEE--------------------------------RERIKE MACMU3_178_PE13 ENSMMUG00000006527 ------------------------------------------------------------------------------------------------------------------------ MACMU3_178_PE14 ISOFORMIN ------------------------------------------------------------------------------------------------------------------------ MACMU3_178_PE15 ISOFORMIN ------------------------------------------------------------------------------------------------------------------------ MACMU3_178_PE16 ISOFORMIN ---------------KERAEAERVRLEA-----EERERIKAEQDKKIADERARIEAEEKAAAQE------R-ERREAEERERIREEEKRAAEERQRIK-EEEKRAAEERQRIKEEEKRAA MICMUGS_3600_PE2 NOISO ---------------RERAEAERARLEA-----EERERIKA---EQEKKIADEQARIEAEEKAA------L-QERERREAEERERREAEEREKREAEE-RKRRETE-ERERK-------- MONDO8_203_PE5 ENSMODG00000014124 EAEAEKL--------RLEAEAEK-------------LRLEA---EQERKAEEERMRIEAEEREA------A-QEKERKEAEE--------------------------------RERIKE MONDO8_203_PE6 ISOFORMIN EAEAE------------------------------------------------------------------------------------------------------------------- MONDO8_203_PE7 ISOFORMIN ------------------------------------------------------------------------------------------------------------------------ MONDO8_203_PE8 ISOFORMIN ------------------------------------------------------------------------------------------------------------------------ MOUSE6_PE402 ISOFORMIN ------------------------------------------------------------------------------------------------------------------------ MOUSE6_PE404 ISOFORMIN ---------------RERAEAERLRLEV-----EGQEQERI-KAEQDRKLAEERARVEAEQKAA------A-EERERREAEERERREAEERERREAEE-RAE------QARIQEE----- MOUSE6_PE405 ISOFORMIN ------------------------------------------------------------------------------------------------------------------------ MOUSE6_PE406 ISOFORMIN ------------------------------------------------------------------------------------------------------------------------ MOUSE6_PE407 ISOFORMIN ------------------------------------------------------------------------------------------------------------------------ MOUSE6_PE412 ENSMUSG00000029761 ---------------RERAEAERLRLEV-----EGQEQERI-KAEQDRKLAEERARVEAEQKAA------A-EERERREAEERERREAEERERREAEE-RAE------QARIQEE----- ORNAN10_9_PE10 ENSOANG00000005001 ---------------GVEADAEKQRLEA-----EERERARA---EQEKRAAAERERRQVNEKKV------Q-EDTLQSVVLK---------------KQVQF-----MKH----LLSALS ORNAN10_9_PE11 ISOFORMIN ---------------GVEADAEKQRLEA-----EERERARA---EQEKRAAAERERRQVNEKKV------Q-EDTLQSVVLK---------------K---------------------- PANTR7_143_PE10 ENSPTRG00000019721 ---------------KERAEAERARLE-------AEERERI-KAEQDKKIADERARIEAEEKAA------A-QERERREAEERERMREEEKRAAEERQ-RIKEEEKRA------------ PANTR7_143_PE11 ISOFORMIN ------------------------------------------------------------------------------------------------------------------------ PANTR7_143_PE12 ISOFORMIN ------------------------------------------------------------------------------------------------------------------------ PIG18_14_PE9 NOISO ------------------------------------------------------------------------------------------------------------------------ POEGU1A_72_PE7 NOISO KAEE-----------EKRAAEEKQKAEEEKRAAEER--AKA---EEEKRAAEERERARAEEER---------------------RAAEEKQRAEEERRAAEEKQRAEEEKRAAEE----- PONPY7_137_PE7 ENSPPYG00000018020 ---------------KERAEAERVRLE-------AEERERI-KAEQDKKIADERARIEAEEKAA------A-QERERREAEERERMREEEKRAAEEKQ-RIKEEEKRAAEERQ---RIKE PONPY7_137_PE8 ISOFORMIN ------------------------------------------------------------------------------------------------------------------------ PTEVA9791_PE1 NOISO ---------------RERTEAERIRLEA-----EERERIKA---EQDQKIAEEKARLEAEEKAR------------------------------------EERETREERREAEERERVKE RABIT7_14_PE10 ISOFORMIN ------------------------------------------------------------------------------------------------------------------------ RABIT7_14_PE8 ISOFORMIN ------------------------------------------------------------------------------------------------------------------------ RABIT7_14_PE9 ENSOCUG00000008127 ------------------------------------------------------------------------------------------------------------------------ RAT4_PE477 ENSRNOG00000010233 ------------------------------------------------------------------------------------------------------------------------ SORARGS_7223_PE1 NOISO ---------------RERVQAERVRLDV-----EERERIKAE---QEHKL-AEIARLEAEETAA------A-QEREKREADYMRMRDEQRKLRDEEQRKRKGDSKAAESQRMEE------ TARSYGS_2912_PE1 NOISO ---------------RERAEAERVRLEA-----EERERIKA---ERDKKIADEQARIEAEEKAA------A-QARERREAEE--------------------------------RERKKG TETNG19_PE282 ENSTNIG00000018525 -----------------------------------R--NPA------------------------------------------------------------------------------- TUPGBGS_1886_PE1 NOISO ---------------RERVEAERLRLE-------AEERERV-KAEQDKKIAEEQARIEAEEKAA------A-QEKERREAEERERRKEEE------------------------------ TURTRGS_1100_PE1 NOISO ---------------RERAEAERARLEA-----EERERI---KVEQEQKIAEEKARKEAEEKAA------A-QERERQEAKERERIKEEERRAAEERQ-RAKERERIKEE---------- XENTR24_3_PE12 NOISO ------------------------------------------------------------------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????

AILMEGL193619_1_PE3 NOISO ---------------------------AEERQRAKAE------EEEKA----KIE-ER-K------LRQLGENR---------------SEVQEKKRKGEKV-DEKREGKWVNEKKVQED ANOCA90_1_PE4 NOISO KEK----------------------REAEEREKAKAEAKRAAE--EKA----KLE-EERLKA------KQKAEE---------------K--KVAEVKGKKVEDKKIEDKQVKEKKVQEE BOVIN4_107_PE3 ENSBTAG00000013953 ------------------------------------------------------------------------------------------------------------------------ CALJA8_118_PE4 ENSCJAG00000012295 EEKRAAEER----QRVKEEEKRAAEER-QRAKAEEEE------K---A----KTE-EQKR------NKQLEEKK---------------NATQETKIKGEKV-KVKIEGKWVNEKKVQED CALJA8_118_PE5 ISOFORMIN ------------------------------------------------------------------------------------------------------------------------ CALJA8_118_PE6 ISOFORMIN ------------------------------------------------------------------------------------------------------------------------ CALJA8_118_PE7 ISOFORMIN ------------------------------------------------------------------------------------------------------------------------ CALJA8_118_PE8 ISOFORMIN ----------------------------QNPDLPTCR--------PQL----NVD-LQKAI-----NLGLQGCI---------------RSTVPNKHHTTTI-PKKKEKKMLAH-----S CALJA8_118_PE9 ISOFORMIN ------------------------------------------------------------------------------------------------------------------------ CANFA16_17_PE5 NOISO QER----------------------KAAEERQRAEA------KDQENA----KLE-EQKLRQ------L-EEHR---------------SEMQEKKRKGEKV-DEKLEGRRGNEKTAPED CAVPO10_14_PE12 ENSCPOG00000023504 EERRAEEERKAAEKRKVEEEKRAEEER-QRAKA--EE------E---A----RIE-EQKR------KKQLEEKK---------------KEMQDTKMTGEKG-KDKREGKWVNEKKVQED CAVPO10_14_PE13 ISOFORMIN ------------------------------------------------------------------------------------------------------------------------ CHICK1_PE1105 ISOFORMIN KER----------------------KAAEERERAKAEEEKRAAEE-KA----RLE-------------------------------------AEKLKEKKKMEEKKAQEEK--------- CHICK1_PE1106 ISOFORMIN KER----------------------KAAEERERAKAEEEKRAAEE-KA----RLE-------------------------------------AEKLKEKKKMEEKKAQEEK--------- CHICK1_PE1107 ISOFORMIN ------------------------------------------------------------------------------------------------------------------------ CHICK1_PE1108 ENSGALG00000013071 KER----------------------KAAEERERAKAEEEKRAAEE-KA----RLE-------------------------------------AEKLKEKKKMEEKKAQEEK--------- CHOHOGS_2782_PE1 NOISO ------------------------------------------------------------------------------------------------------------------------ ECHTEGS_2967_PE1 NOISO -RRRAQ--------------AEEEEKRAEERRRAQAE------EEERA----KRE-EQRR------RQQLEANR---------------NEAQERRSQGERV-PEQLAGKRVPEKKVPEE FELCAGS_1637_PE1 NOISO EER----------------------RAEEERQRAKA------EEEQKA----KLE-EQKR-Q------QLEENR---------------REMQEKKQKGEKV-DEKIEGKRVNEKKVQED FUGRU2_4_PE79 ENSTRUG00000016845 -------------------------KEMEERKK---------EEEEKK----KKEAEEKK------------------------------KKEEDKRKKGELEEK---------KKSISL FUGRU2_4_PE80 ISOFORMIN ------------------------------------------------------------------------------------------------------------------------ GASACGROUPXIX_6_PE49 NOISO ------------------------------------------------------------------------------------------RTSSNKRKKREMEEK---------TKKE-- GORGO7_137_PE8 ENSGGOG00000009728 EEKRAAEER----QRIKEEEKRAAEER-QRARAEEEE------K---A----KVE-EQKR------NKQLEEKK---------------RAMQETKIKGEKV-EQKIEGKWVNEKKAQED GORGO7_137_PE9 ISOFORMIN ---------------------------------ARAE------EEEKA----KVE-EQKR------NKQLEEKK---------------RAMQETKIKGEKV-EQKIEGKWVNEKKAQED HORSE4_93_PE3 NOISO ------------------------------------------------------------------------------------------------------------------------ HS7_PE3870 ISOFORMIN ------------------------------------------------------------------------------------------------------------------------ HS7_PE3871 ISOFORMIN ------------------------------------------------------------------------------------------------------------------------ HS7_PE3872 ISOFORMIN ------------------------------------------------------------------------------------------------------------------------ HS7_PE3875 ENSG00000122786 EEKRAAEER----QRIKEEEKRAAEER-QRARAEEEE------K---A----KVE-EQKR------NKQLEEKK---------------HAMQETKIKGEKV-EQKIEGKWVNEKKAQED HS7_PE3876 ISOFORMIN ------------------------------------------------------------------------------------------------------------------------ HS7_PE3879 ISOFORMIN ------------------------------------------------------------------------------------------------------------------------ HS7_PE3880 ISOFORMIN ------------------------------------------------------------------------------------------------------------------------ HS7_PE3881 ISOFORMIN ------------------------------------------------------------------------------------------------------------------------ HS7_PE3882 ISOFORMIN ------------------------------------------------------------------------------------------------------------------------ HS7_PE3883 ISOFORMIN ------------------------------------------------------------------------------------------------------------------------ LOXAF101_1_PE8 NOISO --------------------------------------------------------------------------------------------------------RVRGGKWAN------- MACEUGS_3523_PE1 NOISO KER----------------------KAAEERERAKAEEKRAAD--EKA----KLE-EQKIKK------QLEEKR---------------K--QQKKIKGGKG-EKKIPEKLVNEKKVQDN MACMU3_178_PE13 ENSMMUG00000006527 ------------------------------------------------------------------------------------------------------------------------ MACMU3_178_PE14 ISOFORMIN ------------------------------------------------------------------------------------------------------------------------ MACMU3_178_PE15 ISOFORMIN ------------------------------------------------------------------------------------------------------------------------ MACMU3_178_PE16 ISOFORMIN EERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAE------EEEKA----KIE-EQKR------NKQLEEKK---------------RAMQETKIKGEKV-EQKIEGKWVNEKKAQED MICMUGS_3600_PE2 NOISO --------------------KQEEKRAAEERQR-AKA------EEEKA----KIE-EQKL------NKQLEEKR---------------RTMQETKVQGEK-----IEGKQVNEKKAQED MONDO8_203_PE5 ENSMODG00000014124 KER----------------------QAAEAREQAKAEEKRVAEAEAKA----KLE-EQIIKK------QLEEKK---------------DKTSEKQIKGGKG-EEKIQEKKVNEKKVQDN MONDO8_203_PE6 ISOFORMIN ------------------------------------------------------------------------------------------------------------------------ MONDO8_203_PE7 ISOFORMIN ------------------------------------------------------------------------------------------------------------------------ MONDO8_203_PE8 ISOFORMIN ------------------------------------------------------------------------------------------------------------------------ MOUSE6_PE402 ISOFORMIN ------------------------------------------------------------------------------------------------------------------------ MOUSE6_PE404 ISOFORMIN -----------------------QRRVAEAQKKAKAE------EEEKA----RIE-EQRQ------KQQLEEQR---------------SEKREAKDKGEKG-AEKADRKGVNEREAPDD MOUSE6_PE405 ISOFORMIN ------------------------------------------------------------------------------------------------------------------------ MOUSE6_PE406 ISOFORMIN ------------------------------------------------------------------------------------------------------------------------ MOUSE6_PE407 ISOFORMIN ------------------------------------------------------------------------------------------------------------------------ MOUSE6_PE412 ENSMUSG00000029761 -----------------------QRRVAEAQKKAKAE------EEEKA----RIE-EQRQ------KQQLEEQR---------------SEKREAKDKGEKG-AEKADRKGVNEREAPDD ORNAN10_9_PE10 ENSOANG00000005001 LGR----------------------GGLEKLAQGSGSLLRFLQDCTEVTVSPDFTPLQRRWACTPEVRSMKANTGAAPGCVSKGRRASPGDAGSARVRGAT-SPRILTGTWAPGRLLEND ORNAN10_9_PE11 ISOFORMIN ------------------------------------------------------------------------------------------------------------------------ PANTR7_143_PE10 ENSPTRG00000019721 -----AEER----QRIKEEEKRAAEER-QRARAEEEE------K---A----KVE-EQKR------NKQLEEKK---------------RAMQETKIKGEKV-EQKIEGKWVNEKKAQED PANTR7_143_PE11 ISOFORMIN ------------------------------------------------------------------------------------------------------------------------ PANTR7_143_PE12 ISOFORMIN ------------------------------------------------------------------------------------------------------------------------ PIG18_14_PE9 NOISO ------------------------------------------------------------------------------------------------------------------------ POEGU1A_72_PE7 NOISO --------------------------------RAKAEEEKRAAEE-KA----KLE-------------------------------------AEKLKEKQKMEEQKIEDKQVKEKEVEDA PONPY7_137_PE7 ENSPPYG00000018020 EEKRAAEER----QRIKEEEKRAAEER-QRARAEEEE------K---A----KVE-EQKR------NKQLEEKK---------------RAMQETKIKGEKV-EQKIEGKWVNEKKAQED PONPY7_137_PE8 ISOFORMIN ------------------------------------------------------------------------------------------------------------------------ PTEVA9791_PE1 NOISO RER----------------------RAAEER-RAKA------EEEEKD----QLE-EQKRAK------Q-LEEK---------------SEVPEKKIKGEEV-EGKVERKWVHEKKGPED RABIT7_14_PE10 ISOFORMIN ------------------------------------------------------------------------------------------------------------------------ RABIT7_14_PE8 ISOFORMIN ------------------------------------------------------------------------------------------------------------------------ RABIT7_14_PE9 ENSOCUG00000008127 ------------------------------------------------------------------------------------------------------------------------ RAT4_PE477 ENSRNOG00000010233 ------------------------------------------------------------------------------------------------------------------------ SORARGS_7223_PE1 NOISO EER--------------KRREEEERKAAEERQRIQAE------EAEKA----KKE-EQKR------QQQLEEKR---------------RERQEEKINGEKV-DAKKEGKWVNEKKATED TARSYGS_2912_PE1 NOISO EEK----------------------RAAEERQRARV------EEEEKA----KTE-EQKLSQ------QLEEKR---------------PSMQETKMKGGKV-EEKMEGKQVNEKKVQED TETNG19_PE282 ENSTNIG00000018525 ----------------------------KE----------------RA--------------------------G-----------------PAAGLEGGEV----------ERSQLLLD TUPGBGS_1886_PE1 NOISO --------------------KRKAEER-QRAQAEEEE------R---A----KIE-EQKL------KKQLEEKR---------------NEVNEKKVKGGKV-EEKLEGKWVNEKKAEED TURTRGS_1100_PE1 NOISO -ERRAA-------------------EERQRA---KAE------EEERA----KIE-EQKR------KKQLEEKK---------------REMQEKKIKGEKV-EEKTEGKWVNEKKVQED XENTR24_3_PE12 NOISO ------------------------------------------------------------------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????

AILMEGL193619_1_PE3 NOISO K--LQTAVQKK---------------------------------------------------QEEEKGAKAQAQREKSQED--KPTFKKEEIKDEKIKKDKEPK-EVKSFLDGKKGFTEV ANOCA90_1_PE4 NOISO I--PSAASLRKK---------------------------------------------------GEEKEVKVEAKKDKLQDEKLRSPFRKEEIKDSKFNRDKAPKEDTKPAWDRKKGIPDS BOVIN4_107_PE3 ENSBTAG00000013953 --------------------------------------------------------------------------------------------KDEKTKKDK-ESKDVKRFLDAKKGFTEV CALJA8_118_PE4 ENSCJAG00000012295 K--LQTAVPKK---------------------------------------------------QENKKGEEKGAKREKLQED--KPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEV CALJA8_118_PE5 ISOFORMIN -----------------------------------------------------------------EKGEEKGAKREKLQED--KPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEV CALJA8_118_PE6 ISOFORMIN -------------------------------------------------------------------------------------------IKDEKIKKDKEPKEEVKSFMDRKKGFTEV CALJA8_118_PE7 ISOFORMIN -----------------------------------------------------------------EKGEEKGAKREKLQED--KPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEV CALJA8_118_PE8 ISOFORMIN P--FQSKFSVT---KSAMNHCAVS--A--ETAEKKPSLSTCKAIRAPTHSCQSCDLTILENKKGEEKGA----KREKLQED--KPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEV CALJA8_118_PE9 ISOFORMIN --------------------------------------------------------------------------------------------KDEKIKKDKEPKEEVKSFMDRKKGFTEV CANFA16_17_PE5 NOISO K--PQTAVQKKQ---------------------------------------------------EEEKGAKAQAQREKSQED--KPAFKKEQIKDEKIKKDKEP-KEVKSFLDGKKGFPEA CAVPO10_14_PE12 ENSCPOG00000023504 K--PQTAVLKK-------------------------------------------------------------------------------QIKDEKIKKDKEPKEEVKTFLDRKKGFTEV CAVPO10_14_PE13 ISOFORMIN ------------------------------------------------------MLTTLANEKEEERGAKEQAQKQKFQED--KPASKTQEIKDEKIKKDKEPKEEVKTFLDRKKGFTEV CHICK1_PE1105 ISOFORMIN ---AQANLLRKQ---------------------------------------------------EEDKEAKVEAKKESLP-EKLQPTSKKDQVKDNK-DKEKAPKEEMKSVWDRKRGVPEQ CHICK1_PE1106 ISOFORMIN ---AQANLLRKQ---------------------------------------------------EEDKEAKVEAKKESLP-EKLQPTSKKDQVKDNK-DKEKAPKEEMKSVWDRKRGVPEQ CHICK1_PE1107 ISOFORMIN -------------------------------------------------------------------------------------------VKDNK-DKEKAPKEEMKSVWDRKRGVPEQ CHICK1_PE1108 ENSGALG00000013071 ---AQANLLRKQ---------------------------------------------------EEDKEAKVEAKKESLP-EKLQPTSKKDQVKDNK-DKEKAPKEEMKSVWDRKRGVPEQ CHOHOGS_2782_PE1 NOISO --------AEE---------------------------------------------------GGEEKGVKVQVKKEKPQED--KTTFKKEEIKDEKIKKDKEPKEEFKSFMDRKKGFTEV ECHTEGS_2967_PE1 NOISO K--AQPAHPKK---------------------------------------------------QGEDKGTKVQLKREKSQED--KATFKKEESKGEKLRKDKEPKEEGKSILDRKKGFTDV FELCAGS_1637_PE1 NOISO K--LQTAVQKKQ---------------------------------------------------EEEKGAKAQAKREKSQED--KPTFK-KEIKDEKIKKDKEP-KEVKSFLDGKKGFTEV FUGRU2_4_PE79 ENSTRUG00000016845 K------L---------YRNPTLK-----LFFL-------------KILSLIS------------------------------VPVFC---FKE-----------EKPKRFGFKDKFE-P FUGRU2_4_PE80 ISOFORMIN ----------------------------------------------------------------------------------------------------------------QKKKFE-P GASACGROUPXIX_6_PE49 NOISO --------------------E-VL-----MSFI---------------ASCPF------------------------------KKTEN---GKE-----------EKPKRFGFKEKQNEA GORGO7_137_PE8 ENSGGOG00000009728 K--LQTAVLKK---------------------------------------------------QGEEKGTKVQAKREKLQED--KPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEV GORGO7_137_PE9 ISOFORMIN K--LQTAVLKKQVQIKKMIKAGEGKNAKTNPWKLTGNKEGERNLLEPFLKKKLCDLTILENKKGEEKGTKVQAKREKLQED--KPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEV HORSE4_93_PE3 NOISO -------------------------------------------------------------------------------------------IKDEKFKKDKERKEEVKSFLDGKKGFTEV HS7_PE3870 ISOFORMIN --------------------------------------------------------------------------------------------KDEKIKKDKEPKEEVKSFMDRKKGFTEV HS7_PE3871 ISOFORMIN --------------------------------------------------------------------------------------------KDEKIKKDKEPKEEVKSFMDRKKGFTEV HS7_PE3872 ISOFORMIN ---------------------------------------------------------------GEEKGTKVQAKREKLQED--KPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEV HS7_PE3875 ENSG00000122786 K--LQTAVLKK---------------------------------------------------QGEEKGTKVQAKREKLQED--KPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEV HS7_PE3876 ISOFORMIN --------------------------------------------------------------------------------------------KDEKIKKDKEPKEEVKSFMDRKKGFTEV HS7_PE3879 ISOFORMIN -------------------------------------------------------------------------------------------IKDEKIKKDKEPKEEVKSFMDRKKGFTEV HS7_PE3880 ISOFORMIN -------------------------------------------------------------------------------------------IKDEKIKKDKEPKEEVKSFMDRKKGFTEV HS7_PE3881 ISOFORMIN -----------------------------------------------------------------EKGTKVQAKREKLQED--KPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEV HS7_PE3882 ISOFORMIN ---------------------------------------------------------------GEEKGTKVQAKREKLQED--KPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEV HS7_PE3883 ISOFORMIN -----------------------------------------------------------------EKGTKVQAKREKLQED--KPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEV LOXAF101_1_PE8 NOISO -----------------------------------------------------------------------------------------ENVKDEKIKKDKEPK-EVKSILDRKKGFTEV MACEUGS_3523_PE1 NOISO K--LQPAVLKTQ---------------------------------------------------GEEKGVKVEVKREKSQED--KPTFKREEIKEEKINKDKGPV-------DRKKGFPEV MACMU3_178_PE13 ENSMMUG00000006527 ---------------------------------------------------------------GEEKGAKVQAKREKLQED--KPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEV MACMU3_178_PE14 ISOFORMIN -------------------------------------------------------------------------------------------IKDEKIKKDKEPKEEVKSFMDRKKGFTEV MACMU3_178_PE15 ISOFORMIN -----------------------------------------------------------------EKGAKVQAKREKLQED--KPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEV MACMU3_178_PE16 ISOFORMIN K--LQTAVLKK---------------------------------------------------QGEEKGAKVQAKREKLQED--KPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEV MICMUGS_3600_PE2 NOISO K--LQTPVLKK---------------------------------------------------QEEEKGAKVQAIRDKSQED--KPAFKKQEIKDEKIKKDKEPKEEIKSFMDRKKGFTEV MONDO8_203_PE5 ENSMODG00000014124 K--LQPAVLKTQ---------------------------------------------------GEEKGVKVEVKREKSQED--KPTFKKEEIKEEKTIKDKGPKEDIKSNWDRKKGFPEV MONDO8_203_PE6 ISOFORMIN ---------------------------------------------------------------------------------------KNNQIKEEKTIKDKGPKEDIKSNWDRKKGFPEV MONDO8_203_PE7 ISOFORMIN -------------------------------------------------------------------------------------------IKEEKTIKDKGPKEDIKSNWDRKKGFPEV MONDO8_203_PE8 ISOFORMIN -----------------------------------------------------------------------------------KYYLRNNQIKEEKTIKDKGPKEDIKSNWDRKKGFPEV MOUSE6_PE402 ISOFORMIN --------------------------------------------------------------------------------------------KDEKIKKDKEPKEEVKSFLDRKKGFTEV MOUSE6_PE404 ISOFORMIN R--LQTAVPKT---------------------------------------------------QEEEKGVKGQAQRQKPRDD--KPAFRKEEIKDEKIKKDKEPKEEVKSFLDRKKGFTEV MOUSE6_PE405 ISOFORMIN --------------------------------------------------------------------------------------------KDEKIKKDKEPKEEVKSFLDRKKGFTEV MOUSE6_PE406 ISOFORMIN -------------------------------------------------------------------------------------------IKDEKIKKDKEPKEEVKSFLDRKKGFTEV MOUSE6_PE407 ISOFORMIN -----------------------------------------------------------------------------PRDD--KPAFRKEEIKDEKIKKDKEPKEEVKSFLDRKKGFTEV MOUSE6_PE412 ENSMUSG00000029761 R--LQTAVPKT---------------------------------------------------QEEEKGVKGQAQRQKPRDD--KPAFRKEEIKDEKIKKDKEPKEEVKSFLDRKKGFTEV ORNAN10_9_PE10 ENSOANG00000005001 ----LSILKNEK---------------------------------------------------GEERGIKVETKREKAQED--RPAFRKEEITAEKTNKDQGPREDIKSSWDRKKGFPET ORNAN10_9_PE11 ISOFORMIN -----------Q---------------------------------------------------GEERGIKVETKREKAQED--RPAFRKEEITAEKTNKDQGPREDIKSSWDRKKGFPET PANTR7_143_PE10 ENSPTRG00000019721 K--LQTAVLKK---------------------------------------------------QGEEKGTKVQANREKFQED--KPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEV PANTR7_143_PE11 ISOFORMIN --------------------------------------------------------------------------------------------KDEKIKKDKEPKEEVKSFMDRKKGFTEV PANTR7_143_PE12 ISOFORMIN -----------------------------------------------------------------EKGTKVQANREKFQED--KPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEV PIG18_14_PE9 NOISO ----------------------------------------------------------------EERGAKVQAKREKPQED--KPTFKKEEIKDEKTKKDKERKEEVKSFLGGKKGLTDV POEGU1A_72_PE7 NOISO K--PQAAVLKKQVHYKNWPNAQHM----MELWL------------------------HTGLVRKHSEEEKVEAKKEKLPEEKLQATSIKDQVKDDK---DKEPKEEMKSVWDRKKGVPEQ PONPY7_137_PE7 ENSPPYG00000018020 K--LQTAVLKK---------------------------------------------------QGEEKGAKVQAKREKLQED--KPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEV PONPY7_137_PE8 ISOFORMIN -------------------------------------------------------------------------------------------IKDEKIKKDKEPKEEVKSFMDRKKGFTEV PTEVA9791_PE1 NOISO K--CQTAVQKKQ---------------------------------------------------EEEKGAKVQPKREKSQED--KPTFKKEEIKDEKMKKDKEPREDVKSFLDGKKGFTEV RABIT7_14_PE10 ISOFORMIN ----------QK---------------------------------------------------EEEKRAKGQAQKEKSPED--KPAFRKEEVKDEKIKKDKEAKEEVKSFMDRKKGFTDV RABIT7_14_PE8 ISOFORMIN ----------KK---------------------------------------------------DEKEREDGE----EEKSK--QESVGENQVKDEKIKKDKEAKEEVKSFMDRKKGFTDV RABIT7_14_PE9 ENSOCUG00000008127 ----------KK---------------------------------------------------DEKEREDGE----EEKSK--QESVGENQVKDEKIKKDKEAKEEVKSFMDRKKGFTDV RAT4_PE477 ENSRNOG00000010233 -------------------------------------------------------------------------------------------IKDEKIKKDKEPKEEVKNFLDRKKGFTEV SORARGS_7223_PE1 NOISO K--LPTAAPKK---------------------------------------------------QGEEKGAKVPAKREQSQED--KPSYKKEEVKDEKMKKDKEPKGEVKSFLDGKKGFTEV TARSYGS_2912_PE1 NOISO K--PQTAVLKKQ---------------------------------------------------EEEKGAKVQAKREKFQED--KPPHKKEEIKDEKMKKDKEPKEEVKSFMDRKKGFTEV TETNG19_PE282 ENSTNIG00000018525 PLSPPPALAEKH------------------------------------------------------------------------QTFPVAFSGTSKLREYSPP----------IRSTPK- TUPGBGS_1886_PE1 NOISO R--LQTAVLKK---------------------------------------------------QEEEKGAKVQTQRGKSQED--KPTFKKEEIKDEKIKKDKEPKEEVKSFLDRKKGFTEV TURTRGS_1100_PE1 NOISO K--LQTAVQKK---------------------------------------------------QEEERGAKMQAKRGKSQED--KPTFKKEEIKDEKTKRDKES-KEVKSFLDGKKGFTEM XENTR24_3_PE12 NOISO ------------------------------------------------------------------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????????????????????????????????????KDEK??KDK?PKEE?KS??DRKKGF?E?

AILMEGL193619_1_PE3 NOISO KSQNGEFM----THKLKHTE----NTFSRPGAG--------ARGSEAKEAE---GASQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAAQ-ELEE----LK--------KKREERRKV ANOCA90_1_PE4 NOISO KPQNGERFPEPPAHKLKHTE----NAFSRPGLKD------------SEESK---PVSHPEAGKRVDELRRRRGENENEEFEKMKQKQQEAAV-ELEELK------------KKREERRKI BOVIN4_107_PE3 ENSBTAG00000013953 KSQNGEFM----THKLKHAE----NTFSRAGGR--------VS--EAKEAE---GTSQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAAL-ELEE----LK--------KKREERRKV CALJA8_118_PE4 ENSCJAG00000012295 KSQNGEFM----THKLKHTE----NTFSRPGGK--------AS-VDTKEAE---GAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAAL-ELEE----LK--------KKREERRKV CALJA8_118_PE5 ISOFORMIN KSQNGEFM----THKLKHTE----NTFSRPGGK--------AS-VDTKEAE---GAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAAL-ELEE----LK--------KKREERRKV CALJA8_118_PE6 ISOFORMIN KSQNGEFM----THKLKHTE----NTFSRPGGK--------AS-VDTKEAE---GAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAAL-ELEE----LK--------KKREERRKV CALJA8_118_PE7 ISOFORMIN KSQNGEFM----THKLKHTE----NTFSRPGGK--------AS-VDTKEAE---GAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAAL-ELEE----LK--------KKREERRKV CALJA8_118_PE8 ISOFORMIN KSQNGEFM----THKLKHTE----NTFSRPGGK---------ASVDTKEAE---GAPQVEAGKRLEELRRRRGETESEEFEKLKVSLVLTHY-PILPLKKEKLESWR----------RFI CALJA8_118_PE9 ISOFORMIN KSQNGEFM----THKLKHTE----NTFSRPGGK--------AS-VDTKEAE---GAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAAL-ELEE----LK--------KKREERRKV CANFA16_17_PE5 NOISO KSQNGEFM----THKLKHTE----NTFSRPGAGA--------RASEAKEAE---GAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAA-QELEELK------------KKREERRKV CAVPO10_14_PE12 ENSCPOG00000023504 KSQNGEFM----THKLKVTE----NAFSRPGG--------------SKEAE---GAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAAL-ELEE----LK--------KKREERRKV CAVPO10_14_PE13 ISOFORMIN KSQNGEFM----THKLKVTE----NAFSPSRPG------------GSKEAE---GAPQVEAGKRLEELRRRRGETESEEFEKLVKNQKPNSG-LSED---SWTNKWYSQYCSYREVERSL CHICK1_PE1105 ISOFORMIN KAQNGERE--LTTPKLKSTE----NAFGRIRNGD--------SQNLLRTEDFEEVEENKKRLSKTKRSNLKGAANAEAGSEKLKEKQQEAAV-ELDELK------------KRREERRKI CHICK1_PE1106 ISOFORMIN KAQNGERE--LTTPKLKSTE----NAFGR--------------------------------------SNLKGAANAEAGSEKLKEKQQEAAV-ELDELK------------KRREERRKI CHICK1_PE1107 ISOFORMIN KAQNGERE--LTTPKLKSTE----NAFGRAGGLL----------GVFGEQPCS--SQKVAGKKKGIRSNLKGAANAEAGSEKLKEKQQEAAV-ELDELK------------KRREERRKI CHICK1_PE1108 ENSGALG00000013071 KAQNGERE--LTTPKLKSTE----NAFGR--------------------------------------SNLKGAANAEAGSEKLKEKQQEAAV-ELDELK------------KRREERRKI CHOHOGS_2782_PE1 NOISO KSQNGEFM----THKLKHTE----NIFSRGGGK--------AS-AETKEAE---AASQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAAV-ELEE----LK--------KKREERRKV ECHTEGS_2967_PE1 NOISO KAQNGDFM----AHKLKPTE----NTFSRGGAR---------PSSETKETE---ATSQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAAL-ELEELK------------KKREERRKV FELCAGS_1637_PE1 NOISO KSQNGEFM----THKLKHTE----NTFXXXXXXX--------XXXXXXXXX---XXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXXELEELK------------KKREERRKV FUGRU2_4_PE79 ENSTRUG00000016845 PKQNVSPF----ENKLRKTEKTSRNSLQRPNLRSSESPVAFSTVRDAVPPTSPDDVEKKEAERKLQELKRRRNDAESEELEKMKQKQQDAEA-ELEGLK------------KKREERRRI FUGRU2_4_PE80 ISOFORMIN PKQNVSPF----ENKLRKTEKTSRYRSE-----------------TLFNAQTPDDVEKKEAERKLQELKRRRNDAESEELEKMKQKQQDAEA-ELEGLK------------KKREERRRI GASACGROUPXIX_6_PE49 NOISO TKQNGGLF----ENKLKKAEKTS--------------------SRDIVPSNKAGGAEQQEAERKLQELKRRRNDAESEDFSTLRTKGIVAAS-FGSGLT------------ETRL----- GORGO7_137_PE8 ENSGGOG00000009728 KSQNGEFV----THKLKHTE----NTFSRPGGR--------AS-VDTKEAE---GAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAAL-ELEE----LK--------KKREERRKV GORGO7_137_PE9 ISOFORMIN KSQNGEFV----THKLKHTE----NTFRRWKLKGRLQAKAWRASVDTKEAE---GAPQVEAGKRLEELRRRRGETESEEFEKLK------------------------------------ HORSE4_93_PE3 NOISO KSQNGEFM----THKLKHTE----NVFSRPGAK--------VG--EAKEAE---GASQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAAL-ELEE----LK--------KKREERRKV HS7_PE3870 ISOFORMIN KSQNGEFM----THKLKHTE----NTFSRPGGR--------AS-VDTKEAE---GAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAAL-ELEE----LK--------KKREERRKV HS7_PE3871 ISOFORMIN KSQNGEFM----THKLKHTE----NTFSRPGGR--------AS-VDTKEAE---GAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAAL-ELEE----LK--------KKREERRKV HS7_PE3872 ISOFORMIN KSQNGEFM----THKLKHTE----NTFSRPGGR--------AS-VDTKEAE---GAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAAL-ELEE----LK--------KKREERRKV HS7_PE3875 ENSG00000122786 KSQNGEFM----THKLKHTE----NTFSRPGGR--------AS-VDTKEAE---GAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAAL-ELEE----LK--------KKREERRKV HS7_PE3876 ISOFORMIN KSQNGEFM----THKLKHTE----NTFSRPGGR--------AS-VDTKEAE---GAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAAL-ELEE----LK--------KKREERRKV HS7_PE3879 ISOFORMIN KSQNGEFM----THKLKHTE----NTFSRPGGR--------AS-VDTKEAE---GAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAAL-ELEE----LK--------KKREERRKV HS7_PE3880 ISOFORMIN KSQNGEFM----THKLKHTE----NTFSRPGGR--------AS-VDTKEAE---GAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAAL-ELEE----LK--------KKREERRKV HS7_PE3881 ISOFORMIN KSQNGEFM----THKLKHTE----NTFSRPGGR--------AS-VDTKEAE---GAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAAL-ELEE----LK--------KKREERRKV HS7_PE3882 ISOFORMIN KSQNGEFM----THKLKHTE----NTFSRPGGR--------AS-VDTKEAE---GAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAAL-ELEE----LK--------KKREERRKV HS7_PE3883 ISOFORMIN KSQNGEFM----THKLKHTE----NTFSRPGGR--------AS-VDTKEAE---GAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAAL-ELEE----LK--------KKREERRKV LOXAF101_1_PE8 NOISO KTQNGEFM----THKLKHTE----NTFRPTNRSGGR------PSRRPRRPK---AASQVEAGQRLEELRRRRAKSERRDYKRLHGSLRKSSI-EVVHLGPSSKRD------------RGV MACEUGS_3523_PE1 NOISO KSQNGELT----THKLKHTE----NIFSRSGGKG---------SVDTKEAE---PTSQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAAL-ELEELK------------KKREERRKV MACMU3_178_PE13 ENSMMUG00000006527 KSQNGEFM----THKLKHTE----NTFSRPGGR--------AS-VDTKEAE---GAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAAL-ELEE----LK--------KKREERRKV MACMU3_178_PE14 ISOFORMIN KSQNGEFM----THKLKHTE----NTFSRPGGR--------AS-VDTKEAE---GAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAAL-ELEE----LK--------KKREERRKV MACMU3_178_PE15 ISOFORMIN KSQNGEFM----THKLKHTE----NTFSRPGGR--------AS-VDTKEAE---GAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAAL-ELEE----LK--------KKREERRKV MACMU3_178_PE16 ISOFORMIN KSQNGEFM----THKLKHTE----NTFSRPGGR--------AS-VDTKEAE---GAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAAL-ELEE----LK--------KKREERRKV MICMUGS_3600_PE2 NOISO KSQNGEFM----THKLKHAE----NTFSLVGGRG-----------AVTEAE---GSFQVECGKRLNELHPRRRENESEEFEKLKQKQQEAAL-ELEELK------------KKREERRKV MONDO8_203_PE5 ENSMODG00000014124 KSQNGELT----THKLKHTE----NTFSRSGGKG---------IMDTKEAE---AASQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAAL-ELEELK------------KKREERRKV MONDO8_203_PE6 ISOFORMIN KSQNGELT----THKLKHTE----NTFS--GGKG---------IMDTKEAE---AASQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAAL-ELEELK------------KKREERRKV MONDO8_203_PE7 ISOFORMIN KSQNGELT----THKLKHTE----NTFSRSGGKG---------IMDTKEAE---AASQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAAL-ELEELK------------KKREERRKV MONDO8_203_PE8 ISOFORMIN KSQNGELT----THKLKHTE----NTFSRSGGKG---------IMDTKEAE---AASQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAAL-ELEELK------------KKREERRKV MOUSE6_PE402 ISOFORMIN KAQNGEFM----THKLKQTE----NAFS--RSG--------GRASGDKEAE---GAPQVEAGKRLEELRRRRGETENEEFEKLKQKQQEAAL-ELEE----LK--------KKREERRKV MOUSE6_PE404 ISOFORMIN KAQNGEFM----THKLKQTE----NAFS--RSG--------GRASGDKEAE---GAPQVEAGKRLEELRRRRGETENEEFEKLKQKQQEAAL-ELEE----LK--------KKREERRKV MOUSE6_PE405 ISOFORMIN KAQNGEFM----THKLKQTE----NAFSPSRSG--------GRASGDKEAE---GAPQVEAGKRLEELRRRRGETENEEFEKLKQKQQEAAL-ELEE----LK--------KKREERRKV MOUSE6_PE406 ISOFORMIN KAQNGEFM----THKLKQTE----NAFSPSRSG--------GRASGDKEAE---GAPQVEAGKRLEELRRRRGETENEEFEKLKQKQQEAAL-ELEE----LK--------KKREERRKV MOUSE6_PE407 ISOFORMIN KAQNGEFM----THKLKQTE----NAFS--RSG--------GRASGDKEAE---GAPQVEAGKRLEELRRRRGETENEEFEKLKQKQQEAAL-ELEE----LK--------KKREERRKV MOUSE6_PE412 ENSMUSG00000029761 KAQNGEFM----THKLKQTE----NAFS--RSG--------GRASGDKEAE---GAPQVEAGKRLEELRRRRGETENEEFEKLKQKQQEAAL-ELEE----LK--------KKREERRKV ORNAN10_9_PE10 ENSOANG00000005001 KSQNGERVQEFTTHRLKHTE----STFSHSRGKA--------G---ADTEE---AESQVEAGRRLEELRRRRGETEKSPFSIPLRQGQRVGGRGQQEAR------------KQREKKVPP ORNAN10_9_PE11 ISOFORMIN KSQNGERVQEFTTHRLKHTE----STFS--RGKA--------G---ADTEE---AESQVEAGRRLEELRRRRGETEKSPFSIPLRQGQRVGGRGQQEAR------------KQREKKVPP PANTR7_143_PE10 ENSPTRG00000019721 KSQNGEFM----THKLKHTE----NTFSRPGGR--------AS-VDTKEAE---GAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAAL-ELEE----LK--------KKREERRKV PANTR7_143_PE11 ISOFORMIN KSQNGEFM----THKLKHTE----NTFSRPGGR--------AS-VDTKEAE---GAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAAL-ELEE----LK--------KKREERRKV PANTR7_143_PE12 ISOFORMIN KSQNGEFM----THKLKHTE----NTFSRPGGR--------AS-VDTKEAE---GAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAAL-ELEE----LK--------KKREERRKV PIG18_14_PE9 NOISO KAQNGEFM----THKLKHTE----NTFSRPGGR--------AS-E-AKETE---GASQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAAL-ELEE----LK--------KKREERRKV POEGU1A_72_PE7 NOISO KAQNGERE--LPASKLKPTE----NAFGRSGAKG--------ATEEAKPGA--------EALKRLEDQRRRRGESESEELEKLKEKQQEAAA-ELDELK------------KRREERRKI PONPY7_137_PE7 ENSPPYG00000018020 KSQNGEFM----THKLKHTE----NTFSRPGGR--------AS-VDTKEAE---GAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAAL-ELEE----LK--------KKREERRKV PONPY7_137_PE8 ISOFORMIN KSQNGEFM----THKLKHTE----NTFSRPGGR--------AS-VDTKEAE---GAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAAL-ELEE----LK--------KKREERRKV PTEVA9791_PE1 NOISO KSQNGEFM----THKLKHTE----NTFSRPGG----------RAGEAKEAE---GASQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAAL-ELEELK------------KKREERRKV RABIT7_14_PE10 ISOFORMIN KSQNGEFM----THKLKHAE----NTFSPGRSGA--------RPSG--------DAQEAEAGKRLEELRRRRGETESEEFEKLKQKQQEAAL-ELEELK------------KKREERRKV RABIT7_14_PE8 ISOFORMIN KSQNGEFM----THKLKHAE----NTFSPGRSGA--------RPSG--------DAQEAEAGKRLEELRRRRGETESEEFEKLKDRKVREELSDMGSLP------------KFPEGCDDY RABIT7_14_PE9 ENSOCUG00000008127 KSQNGEFM----THKLKHAE----NTFSPGRSGA--------RPSG--------DAQEAEAGKRLEELRRRRGETESEEFEKLKQKQQEAAL-ELEELK------------KKREERRKV RAT4_PE477 ENSRNOG00000010233 KAQNGEFM----THKLKQTE----NAFSPSRSG--------GRASGDKEAE---GAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAAL-ELEE----LK--------KKREERRKV SORARGS_7223_PE1 NOISO KSQNGEFM----THKLKPTE----NTFXXXXXXA----------SEV---------KEAEEAGRLEELRRRRGETESEEFEKLKQKQQEAAL-ELEELK------------KKREERRKV TARSYGS_2912_PE1 NOISO KSHNGEFM----THKLKHTE----NTFXXXXXXX--------XX--DVMAK---DTPQTGIGRRVKK-HERRGETVSGEFERIKQKQHKPAL-ELEELW------------RKREERRRV TETNG19_PE282 ENSTNIG00000018525 --------------QHSQPE----RTLSRSSLRS----------SEEQE---EQDQARLEAERKLEELKRRRGDAESEEFERMRQKQQEAEA-ELNFIVKAA--SFPRLVFKMSSHN-KA TUPGBGS_1886_PE1 NOISO KSQNGEFM----THKLKHAE----NTSSRPGGR--------AS-GDTKEAE---GASQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAAL-ELEE----LK--------KKREERRKV TURTRGS_1100_PE1 NOISO KSQNGEFM----THKLKHTE----NTFSRPGGR--------AS--EAKEAE---GASQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAAL-ELEE----LK--------KKREERRKV XENTR24_3_PE12 NOISO --------------------------------------------------------------------RRRRGENESGEFDKLKQKQQEAAV-ELEGLK------------KRREERRKI MATCH CONSENSUS K?QNGE??????THKLK?TE????N?FS???????????????????????????????EAGKRLEELRRRRGETE?EEFEKLKQKQQEAA??ELEE??????????????K?REERRK?

AILMEGL193619_1_PE3 NOISO LEEEEQKRKQEEAERKVREEEEKRR-LKE----EIERRRAEAAEKRQKMPEDSLSD---DKKPFKCFTPKGSSLKIEERAEFLNKSVQKS-SGVKSTHQAAVVSKIDSRLEQYTSAIEGT ANOCA90_1_PE4 NOISO LEEEEQKRKKDEAERKSREEEEKRR-LKE----EIERRRAEAAEKRQKMPEEAQTD---EKKPFKCFTPKGSSLKIEERAEFLNKSAQK--SGLKPTHTSPVVSKIDSRLEQYTSAIEGN BOVIN4_107_PE3 ENSBTAG00000013953 LEEEEQRKKQEEAERKVREEEEKRR-LKE----EIERRRAEAAEKRQKMPEDGLSE---DKKPFKCFTPKGSSLKIEERAEFLNKSVQK--SGVKSTHQAAVVSKIDSRLEQYTSAIEGT CALJA8_118_PE4 ENSCJAG00000012295 LEEEEQRRKQEEADRKLREEEEKRR-LKE----EIERRRAEAAEKRQKMPEDGLSD---DKKPFKCFTPKGSSLKIEERAEFLNKSVQKS-SGVKSTHQAAVVSKIDSRLEQYTSAIEGT CALJA8_118_PE5 ISOFORMIN LEEEEQRRKQEEADRKLREEEEKRR-LKE----EIERRRAEAAEKRQKMPEDGLSD---DKKPFKCFTPKGSSLKIEERAEFLNKSVQK--SGVKSTHQAAVVSKIDSRLEQYTSAIEGT CALJA8_118_PE6 ISOFORMIN LEEEEQRRKQEEADRKLREEEEKRR-LKE----EIERRRAEAAEKRQKMPEDGLSD---DKKPFKCFTPKGSSLKIEERAEFLNKSVQKS-SGVKSTHQAAVVSKIDSRLEQYTSAIEGT CALJA8_118_PE7 ISOFORMIN LEEEEQRRKQEEADRKLREEEEKRR-LKE----EIERRRAEAAEKRQKMPEDGLSD---DKKPFKCFTPKGSSLKIEERAEFLNKSVQKS-SGVKSTHQAAVVSKIDSRLEQYTSAIEGT CALJA8_118_PE8 ISOFORMIN GFNELQLIKQTQASRSQKCEEEKRR-LKE----EIERRRAEAAEKRQKMPEDGLSD---DKKPFKCFTPKGSSLKIEERAEFLNKSVQKS-SGVKSTHQAAVVSKIDSRLEQYTSAIE-- CALJA8_118_PE9 ISOFORMIN LEEEEQRRKQEEADRKLREEEEKRR-LKE----EIERRRAEAAEKRQKMPEDGLSD---DKKPFKCFTPKGSSLKIEERAEFLNKSVQKS-SGVKSTHQAAVVSKIDSRLEQYTSAIEGT CANFA16_17_PE5 NOISO LEEEEQKRKQEEAERKVREEEEKRR-LKE----EIERRRAEAAEKRQKMPEDNLSD---DKKPFKCFTPKGSSLKIEERAEFLNKSVQKS-SGVKSTHQAAVVSKIDSRLEQYTSAIEGT CAVPO10_14_PE12 ENSCPOG00000023504 LEEEEQKKKQEEADRRAREEEEKRR-LKE----EIERRRAEAAEKRQKMPEDGLSD---EKKPFKCFTPKGSSLKIEERAEFLNKSVQKS-SGVKSTHQAAVVSKIDSRLEQYTSAIEGT CAVPO10_14_PE13 ISOFORMIN L------------NDGGDREEEKRR-LKE----EIERRRAEAAEKRQKMPEDGLSD---EKKPFKCFTPKGSSLKIEERAEFLNKSVQKS-SGVKSTHQAAVVSKIDSRLEQYTSAIEGT CHICK1_PE1105 ISOFORMIN LEEEEQKKKQEEAERKIREEEEKKR-MKE----EIERRRAEAAEKRQKVPEDGVSE---EKKPFKCFSPKGSSLKIEERAEFLNKSAQKR-SGMKPAHTTAVVSKIDSRLEQYTSAVVGN CHICK1_PE1106 ISOFORMIN LEEEEQKKKQEEAERKIREEEEKKR-MKE----EIERRRAEAAEKRQKVPEDGVSE---EKKPFKCFSPKGSSLKIEERAEFLNKSAQ-K-SGMKPAHTTAVVSKIDSRLEQYTSAVVGN CHICK1_PE1107 ISOFORMIN LEEEEQKKKQEEAERKIREEEEKKR-MKE----EIERRRAEAAEKRQKVPEDGVSE---EKKPFKCFSPKGSSLKIEERAEFLNKSAQ-K-SGMKPAHTTAVVSKIDSRLEQYTSAVVGN CHICK1_PE1108 ENSGALG00000013071 LEEEEQKKKQEEAERKIREEEEKKR-MKE----EIERRRAEAAEKRQKVPEDGVSE---EKKPFKCFSPKGSSLKIEERAEFLNKSAQ-K-SGMKPAHTTAVVSKIDSRLEQYTSAVVGN CHOHOGS_2782_PE1 NOISO LEEEEQKKKQEEAERKVREEEEKRR-LKE----EIEKRRAEAAEKRQKMPEDGLSD---EKKPFKCFTPKGSSLKXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXTSAIEGT ECHTEGS_2967_PE1 NOISO LEEEEQKKKQEEAERKAREEXXXXX-XXX----XXXXXXXXXXXXXXXXXXXXXXX---XXXXXXXXXXXXXXXXIEERAEFLNKSAQKS-SGVKSTHQATVVSKIDSRLEQYTSAIEGT FELCAGS_1637_PE1 NOISO LEEEEQRRKQEEAERKVREEEEKRR-LRE----EIEKRRAEAAEKRQKMPEDSLSD---DKKPFKCFTPKGSSLKIEERAEFLNKSVQKS-SGVKSTHQAAVVSKIDSRLEQYTSAIE-- FUGRU2_4_PE79 ENSTRUG00000016845 MEEEERQKKQELEEKKARETEERKR-MRE----EIEKRRAEAAERKKQMEVEESAK-----PAFAINPKGSSKVQIGEKAEFLSKSAQKS--VTPRVSHTPIVSRIGNRMDQYASAIQGN FUGRU2_4_PE80 ISOFORMIN MEEEERQKKQELEEKKARETEERKR-MRE----EIEKRRAEAAERKKQMEVEESAK-----PAFAINPKGSSKVQIGEKAEFLSKSAQKS--VTPRVSHTPIVSRIGNRMDQYASAIQGN GASACGROUPXIX_6_PE49 NOISO YGHSQRLLKGEFQFNRSASLSQVVRHFYSLMCLCFSLFHF-KSPGISQIFLDDSIKIRWERAVLKHRTVTGSFSRIGAKAEFLSKSAQKS--TAARGSHTPIVSKIGNRLEQYTSAIQGN GORGO7_137_PE8 ENSGGOG00000009728 LEEEEQRRKQEEADRKLREEEEKKR-LKE----EIERRRAEAAEKRQKMPEDGLSD---DKKPFKCFTPKGSSLKIEERAEFLNKSVQKS-SGVKSTHQAAVVSKIDSRLEQYTSAIEGT GORGO7_137_PE9 ISOFORMIN ------------ADRKLREEEEKKR-LKE----EIERRRAEAAEKRQKMPEDGLSD---DKKPFKCFTPKGSSLKIEERAEFLNKSVQK--SGVKSTHQAAVVSKIDSRLEQYTSAIEGT HORSE4_93_PE3 NOISO LEEEEQRRKQEEAERKVREEEEKRR-LKE----EIERRRAEAAEKRQKMPEDGLSE---DKKPFKCFTPKGSSLKIEERAEFLNKSVQK--SGVKSTHQAAVVSKIDSRLEQYTSAIEGT HS7_PE3870 ISOFORMIN LEEEEQRRKQEEADRKLREEEEKRR-LKE----EIERRRAEAAEKRQKMPEDGLSD---DKKPFKCFTPKGSSLKIEERAEFLNKSVQKS-SGVKSTHQAAIVSKIDSRLEQYTSAIEGT HS7_PE3871 ISOFORMIN LEEEEQRRKQEEADRKLREEEEKRR-LKE----EIERRRAEAAEKRQKMPEDGLSD---DKKPFKCFTPKGSSLKIEERAEFLNKSVQKS-SGVKSTHQAAIVSKIDSRLEQYTSAIEGT HS7_PE3872 ISOFORMIN LEEEEQRRKQEEADRKLREEEEKRR-LKE----EIERRRAEAAEKRQKMPEDGLSD---DKKPFKCFTPKGSSLKIEERAEFLNKSVQK--SGVKSTHQAAIVSKIDSRLEQYTSAIEGT HS7_PE3875 ENSG00000122786 LEEEEQRRKQEEADRKLREEEEKRR-LKE----EIERRRAEAAEKRQKMPEDGLSD---DKKPFKCFTPKGSSLKIEERAEFLNKSVQKS-SGVKSTHQAAIVSKIDSRLEQYTSAIEGT HS7_PE3876 ISOFORMIN LEEEEQRRKQEEADRKLREEEEKRR-LKE----EIERRRAEAAEKRQKMPEDGLSD---DKKPFKCFTPKGSSLKIEERAEFLNKSVQKS-SGVKSTHQAAIVSKIDSRLEQYTSAIEGT HS7_PE3879 ISOFORMIN LEEEEQRRKQEEADRKLREEEEKRR-LKE----EIERRRAEAAEKRQKMPEDGLSD---DKKPFKCFTPKGSSLKIEERAEFLNKSVQKS-SGVKSTHQAAIVSKIDSRLEQYTSAIEGT HS7_PE3880 ISOFORMIN LEEEEQRRKQEEADRKLREEEEKRR-LKE----EIERRRAEAAEKRQKMPEDGLSD---DKKPFKCFTPKGSSLKIEERAEFLNKSVQKS-SGVKSTHQAAIVSKIDSRLEQYTSAIEGT HS7_PE3881 ISOFORMIN LEEEEQRRKQEEADRKLREEEEKRR-LKE----EIERRRAEAAEKRQKMPEDGLSD---DKKPFKCFTPKGSSLKIEERAEFLNKSVQK--SGVKSTHQAAIVSKIDSRLEQYTSAIEGT HS7_PE3882 ISOFORMIN LEEEEQRRKQEEADRKLREEEEKRR-LKE----EIERRRAEAAEKRQKMPEDGLSD---DKKPFKCFTPKGSSLKIEERAEFLNKSVQKS-SGVKSTHQAAIVSKIDSRLEQYTSAIEGT HS7_PE3883 ISOFORMIN LEEEEQRRKQEEADRKLREEEEKRR-LKE----EIERRRAEAAEKRQKMPEDGLSD---DKKPFKCFTPKGSSLKIEERAEFLNKSVQKS-SGVKSTHQAAIVSKIDSRLEQYTSAIEGT LOXAF101_1_PE8 NOISO Y-EYSRLGMRAQRDDPQSTEEEKRR-LKE----EIERRRAEAAEKRQKMPEDSVSD---DKKPFKCFTPKGSSLKIEERAEFLNKSVQK--SGVKSTHQAAVVSKIDSRLEQYTSAIEGT MACEUGS_3523_PE1 NOISO