Alignment of the gene Family HOG000049252 of HOGENOM

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Threshold: 50% 80% 100%
Size: Bigger Smaller Normal
Isoforms are ON
AILMEGL192953_1_1_PE3 NOISO -PTVGQASYRLQATR-AAMETERGSLVPGE----VEKEVQLRVTPSEVKFLNALAGRVYRLPVTVHNLGHCSQKIRFQEPLKPQFKLILTNLDKALASGLQMTAM----------VEYHP ANOCA266_2_PE12 NOISO -----------------------------------------RITPAELRFVDAAPGGCFRAQLSVQNLQAQSSLLQLSPPERPQFKLIVENQKKPIASGLHITAT----------VEYRP BOVINUN_004_106_PE1 NOISO ---------------STAMETERSSLVARDLDT-TKKDMKLRVTPSEMKFRNAVAGRVYRLPLTVQNLGRSSQKIHFQEPVKPQFKLILTNLDKSLASGLQTTAM----------VEYHP CALJAX_36_PE1 NOISO NTP----------RGS---LVPRGSLVPRDIES-PGRDMNLRVIPPELRFLDATAGSVYHLSFVVHNLGRWNQKIRFEEPTKPQFKLMLTSLDKELAAGLHMTAT----------VEYHP CANFAX_32_PE2 NOISO -PSVGRVSCRLRVTQGATMEAERGSLVPQDGEA-LKKEVQLRVTPSEVKFLDALAGRVYRLPVTVHNLGGSNQKIRFQEPLKPQFKLMLTNLDKALASGLQMTAM----------VEYHP CAVPO33_24_PE1 NOISO NSQLGKLV--WAGPGQTAMGTPGSSSVPRESGS-LKAEVQLRVTPLEMKFCDAMVGKVYRLPITVHNLGRWNKKIRFMEPTKKQFKLMLTNLDKELASGLKTTAM----------VEYHP CHICK1_PE1982 NOISO -----------------------------------RDVDRVRIAPPELRFTAAVPGRRYRAALSVQNLRAQSCRLRLLPPRRSEFKLIVENPENPVAPGLQVKAF----------IEYYP CIOIN2Q_6_PE12 NOISO ----------------------------------------IRISPPVVEFVDATINEVLTLNLVVQNVSKFSKRIRFHAPVTNKFKLHVTNPEKPVAPGLEIQAS----------VEYFN CIOSAREFTIG_17_1_PE70 NOISO ----------------------------------------IRISPPVVEFVDATINEVLTTNLSVQNVSKFSKRIRFHAPVTDKFKLHVSNPERPVAPGLEVQAT----------VEYMN DIPORGS_4839_PE1 NOISO ------------------------------------------------------------------------------EPSKPQFKLILTNLEKELASGLHFTVM----------IEYHP ECHTEGS_9099_PE1 NOISO -------------------MDRRFSLAPCARRN-QKKEVYVRVTPAEVKFFDTVVGRVYRFPITVHNIGHCMQKIQFEEPPKPQXXXXXXXXXXXXXXXXXXXXX----------XXXXX FUGRU36_1_PE11 NOISO ----------------------------------------VRVDPPVVKFKDINVGQRYGMKVTAANVGKTTKKILMEKPASKLFKLPS-GKAEMVAPGLSVGGV----------LEFIP GASACGROUPI_21_PE18 NOISO ----------------------------------------VRVDPPFVEFNGVSVGQVYKTTLTVTNVGKTAKKIRMGKPVLKFFKFSASSTAQLVAPGLSVSGL----------LEFTP GORGOX_38_PE4 NOISO NTQRGSLTIN-VHRGSLAMSIQRGSLVPRAMDS-SGRDMQLRVIPAEVKFLDTMAGKVYRLPITVHNLCRWNQKIRFKEPIKPQFKLMLTSLDKELASGLQMTAM----------VEYHP HORSEX_30_PE2 NOISO ---------------------REGSLVPRDVET--PKEMQLRVTPSEMKFLDTLAGRVYRLPITVHNLGRCNQKIRFQEPVKPQFKLVLANLDKALASGLQMTAI----------VEYHP HSX_PE525 NOISO NTQKGSLTIN-VHRGSLAMSIQRGSLVPRDMDS-SGRDMQLRVIPAEVKFLDTMAGRVYRLPITVHNICRWNQKIRFKEPVKPQFKLMLTSLDKELASGLQMTAM----------VEYHP LAMPAGS_2458_PE1 NOISO ------------------MATERSSLVARNLET-LKKDLQLRVTPSEVKFLDAVAGKVYRLPVTVQNLSQCSQKIRFQEPVKPQFKLLLTNLDKALASGLQTTAI----------VEYHP LOXAF82_1_PE10 NOISO ------------------------------------------------------------------------------------------------------------------------ MACEUGS_7203_PE1 NOISO -----------------------------PLLAMEKTVLWLRLCPAEVRFADVQVGTIYSTEIKVQNIGRSNKKIRF--------L--GPEDPQXXXXXXXXXXXXXXXXXXXXXXXXXX MACMUX_35_PE1 NOISO NTQRGSLTIS-IQRGSLAMSIQRGSFVSRDVDS-PGKDMQLRVIPAEVKFLDTMAGRVYRLPITVHNLGRWNQKIRFKEPIKPQFKLMLTSLDKELASGLQMTAM----------VEYHP MICMUGS_3224_PE1 NOISO ------------------MERERSSLMPLDIES-PKKDMQLRVTPSEMKFLDTVAGRVYRLPITVHNLGRSTQKIRFQEPVKPQFKLILTNLDKALASGLQMTAM----------VEYHP MONDO4_29_PE1 NOISO -------------------------------------------------------------------------KLQF--------KLNLNKDPIPLATGLQVTAT----------VTFKP MOUSEX_PE1109 NOISO ------------------MDAERGSVAPRDIDT-LKKEVQLRVNPLVLKFQDAVSGKVYRLPLTVHNLGRWNQKIRFQEPSKPQFKLLLTSLDKELASGLQMTAM----------VEYHP ORNANULTRA222_9_PE12 NOISO -----------------------------------GAERSVRVSPSRVRFSDVRVGQLYRAALTVQNVGRSSKAIRFQGPRSQQFKLIVTDRDKAVASGLQMTAT----------VEYRP OTOGAGS_5803_PE2 NOISO ------------------------------------------------------------------------------------------------------------------------ PANTRX_36_PE3 ENSPTRG00000021782 ----------------------QRGLVPRDMS---SRDMQLRI--SAVVFLDTMAGRVYRLPITVHN-CRWNQKIRFKEPVKPQFKLMLTSLDKELASGLQMTAM----------VEYHP PANTRX_36_PE4 ISOFORMIN ----------------------QRGLVPRDMS---SRDMQLRI--SAVVFLDTMAGRVYRLPITVHN-CRWNQKIRFKEPVKPQFKLMLTSLDKELASGLQMTAM----------VEYHP PIGX_33_PE1 NOISO -----------------AMETQRSSLLSRDLET-QKKDLQLRVTPSEVKFLDALAGRVYRLPITIHNVGRNSQKIRLQEPVKPQFRLLLTNPDKALASGLQVTAV----------VEYHP POEGU1_9_PE4 ISOFORMIN ----------------------------------------VRIAPAELRFS-AVPGSRHRAGLTVQNLRAGACHLRLLPPHQPQFKLIVENPEKPIASGLQVKAV----------VEYTP POEGU1_9_PE5 ENSTGUG00000006861 -----------------------------------------------------------------------------------QFKLIVENPEKPIASGLQVKAV----------VEYTP PONPYX_36_PE2 NOISO NTQRGSLTIN-VHRSSLAMSIQRGSLVPRDMDS-SGRDMQLRVIPAEVKFLDTMAGRVYRLPITVHNLCRWNQKIRFKEPIKPQFKLMLTSLDKELASGLQMTAM----------VEYHP PROCAGS_5376_PE1 NOISO ------------------------------------------------------------------------------------------------------------------------ PTEVAGS_2757_PE1 NOISO -------------------MDSRGSLVPRDVES--AKEMQLRVTPSEMKFQDTLAGKVYRLPVTIHNLGRTNQKIRFLEPVKPQFKLILXXXXXXXXXXXXXXXX----------XXXXX RABITX_23_PE3 NOISO -----------------SVDMRRSSLVPRDTES-LKKDIQLQVTPLELKFLDTLAGKVYRLPITLHNLGRSNQKIRFQEPTKPQFKLVLTNLEKELASGLQMTAI----------VEYHP RATX_PE602 NOISO ------------------MDLERGSVAPRDVDNTAKKEVQLRVNPLELKFQDAVSGKVYRLPLTVHNLGRWNQKIRFQEPSKPQFKLLLTSLDKELASGLQMTAM----------VEYHP SORARGS_5142_PE1 NOISO ------------------MDLEKSSFNSRDIES-AKRDLQLRVYPTELRFVDAVAGKVYRLSVTLHNVGRSNQKIRFQEPSKPQFKLVMSTLDKALASGLQLTAV----------VEYHP TARSYGS_6009_PE1 NOISO ------------------MDTKRGSFVPQDIEI-PKNDIPLRVTPLRMKFPDTLAGRVYRLPITVQNLGRCNQKIRFQEPIKPQFKLILANLDKELAPGLHVTAM----------XXXXX XENTR71_2_PE7 NOISO -----------------------------------------------------------------------------------QFTFTVQNPEKPIACGLQVTGT----------VEYRP MATCH CONSENSUS ????????????????????????S???????????????LRV?P?E?KF?D???G?VYRLP?TVHNLGR??QKIRF?EP?KPQFKL?LT?LDK?LASGLQ?TA???????????VEYHP

AILMEGL192953_1_1_PE3 NOISO DKDEDTFDQLLISIGK-KTIEIPLVGLIPSCQLEIES----EVNFGTLVADSKVYCKEINIINRGRAPGTFKAEYQGQLP--IVIFPSNGIVEPQSLVIVKVD--FCADQPRIVN----- ANOCA266_2_PE12 NOISO DSEEDLQDRLLLQIGK-KIVEIPIIGLIPRCCLQIEP----EINFGTVIANSKVINTEIKITNSGSSPGTFAIKYTGSVP--IIIEPTSGVVEPRSVQLVKLE--ICTDVPRIIN----- BOVINUN_004_106_PE1 NOISO DKNEDICDQLLISIGN-KTIEVPLIGLIPSCQLEIEP----EVNFGTLVASSKVYCKEINIINHGSVPGIFKTEYQGQLS--IVIFPTSGVVQPKSSVVIKVD--FCADQPIVVN----- CALJAX_36_PE1 NOISO DKDENTSDRILISIGS-KSTEIPLIGLIPSCQLAIES----VVDFGTLVANSKVYHKEITITNHGKVPGTFNAEYHGQLP--ILIFPTSGVVDVKSSLAIKVD--FCADQPRIVD----- CANFAX_32_PE2 NOISO DKDEDTFDQLLISIGN-KTIEIPLIGLIPSCQLEIES----EVNFGTLVADSKVYCKEINIVNHGRVPGTFKTEYQGQLP--IVIFPSNGIVEPKSSMIVKVD--FCADEPRIVN----- CAVPO33_24_PE1 NOISO DKDEDTFDQLLILVGT-KTIVVPLMGLIPSCEMEIES----VVDFGTLVSNSKVYSEVIRISNLGTVPGMFKVEYQGQLP--IHIFPNYGVVKPESFIIVKVD--FCADKSRLVN----- CHICK1_PE1982 NOISO ESEEDIEDSLRLLIEE-DIVNIPLVVLIPSCTLETEP----EVDFGTVIASSKIISKEISITNHGSLPGTFKISYNGDIF--LDIEPTRGVVKPKSYQVVKVQ--ICTDVPGVIK----- CIOIN2Q_6_PE12 NOISO DLAEDARDRIILSVDD-DIIEIPLYAYTPTPLLDVEG----PVDFGMVVANSRVLSQEVALINHGSLVGEFKVVYTGSKP--IVITPSSGKVNPKTIQLIKVE--LVTDNPGDVN----- CIOSAREFTIG_17_1_PE70 NOISO NMAEDARDRIILSVDE-DIIEIPLYAYTPTPLLDLEG----PVDFGMVVANSRVLNQEVALINHGSLAGEFKVVYSGSKP--IVITPSSGKVNPKTIQLIKVE--LVTDNPGSIYYLKFK DIPORGS_4839_PE1 NOISO IKNEEISDQLLITVGN-KVIAVPLIXXXXXXXXXXXXXXX----XXXXXXXXXXXXXXXXXXXXXXXXXLFRTDYQGHLP--ILIAPTTGTVKPKSFVVIKVD--FCANQPRIVN----- ECHTEGS_9099_PE1 NOISO XXXXXXXXXXXXXXXX-XXXXXXXXXLIPSCDLDIPP----EVNFGSLVAKSKVHSKEISIRNFGKSPGTFYIEYTGGFP--IFISPARGTVQAQSSVAVKIE--FCADKPLTVN----- FUGRU36_1_PE11 NOISO EKNEEVRDCLNVHVDDRETIEIPLLGIPKACSLLMDS----VVNFGCTAANSQVIIRHHAITNEGSLPGYFHVQYSGDPS--VTISSCSGVILPGGTTWLKVE--LCTDKPRLLV----- GASACGROUPI_21_PE18 NOISO EEEEEVRDCLLNHIDYIETIKIPLLGVLLDCQGLFLPN-RVSTRLWKHAASSQVISKRHHITNQGSAPGVFQLQYNGDPS--VRISPRGGVVAAGATLWLEVE--LRTDRPRQID----- GORGOX_38_PE4 NOISO DKDEDTFDRLLISIEN-KTTEIPLIGLIPSCQLEIES----VVNFGTLVANSKVYSKEITITNHGKAPGVFKAEYHGQLP--ILIFPTSGIVDAKSSMVIKVD--FCADQPRILD----- HORSEX_30_PE2 NOISO DKDEDTFDQLLISIGN-KTLEIPLIGLIPSCQLEIES----EVNFGTLVANSKVHCKEIIIINHGRVPGIFKTEYQGQLP--IVIFPTDGVVEPKSSVVVKVD--FCADQPRTVN----- HSX_PE525 NOISO DKDEDTFDRLLISIEN-KTTEIPLIGLIPSCQLEIES----VVNFGTLVANSKVYSKEITITNHGKAPGIFKAEYHGQLP--ILIFPTSGIVDAKSSMVIKVD--FCADQPRIVD----- LAMPAGS_2458_PE1 NOISO NKDEDTFDQLLISVGN-KTLEIPLIGLIPSCQLEIES----EVNFGILVANNKVHCKEINIVNHGTVPGMFKTEYQGQLP--IVFFPSNGIVQPKSSMVIKVD--FCADQPIIVN----- LOXAF82_1_PE10 NOISO ------------------------------------------------------------------------------------------------------------------------ MACEUGS_7203_PE1 NOISO XXXXXXXXXXXXXXXX-XXXXXXXXXLIPSCHLEIES----SVNFGTIIANSKAICKSISVINCGTIPGSFDIDYKGNLP--ITINPTSGIVDPKSSKNIKIF--ICTDKPRIVN----- MACMUX_35_PE1 NOISO DKDEDTFDRLLISIEN-KTTEIPLIGLIPSCNLEIQS----VVNFGTLVANSKVYSKEVTINNRGKAPGKCFPSYLLTLLEELILFEMSLIVLLKTVYRILIK--ICMYVL--IL----- MICMUGS_3224_PE1 NOISO DKNEDTFDQLLISVGN-KTIEIPLIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----XXXXXXXXXXXXXXXX----XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----- MONDO4_29_PE1 NOISO TKAEDVFEKMYVMVAK-RKIEIPLIGLIPSCHLEIQT----KINFGTVIANSKEICKSINISNHGTIPGSFGIKYTGVLP--ITIQPSNGIVKPKSSQTIKVY--LCTDKPRIVS----- MOUSEX_PE1109 NOISO NKNEDMSDHIFISVGN-KVLDIPLFGLIPVCQLEIVP----VVDFGTLVANSKVHCKEITIINRGKAPGKFKAEYQGQLP--IVISPSSGIVKAKTSMVIKVD--FCADQAQIVN----- ORNANULTRA222_9_PE12 NOISO DNEEDVFDRIFVLVEK-EVIEVPLIGLIPCCQLEIEP----KVNFGTLIANSIVICKEIHVTNHGSAPGAFHVEYKGNLP--IFIQPTGGIVGPKLSEAIKVD--ICTDLPRVVN----- OTOGAGS_5803_PE2 NOISO --------------------------MIPVCKLDIDS----EVNFGTLVANSKVYCKEITIVNHGKAPGTFNTEYQGQLP--IIISPTSGIVAPESSTVIKVD--FCADQPRIVN----- PANTRX_36_PE3 ENSPTRG00000021782 DKDEDTFDRLLISIEN-KTTEIPLIGLIPSCQLEIES----VVNFGTLVANSKVYSKEITITNHGKAPGIFKAEYHGQLP--ILIFPTSGIVDAKSSMVIKVD--FCADQPRIVD----- PANTRX_36_PE4 ISOFORMIN DKDEDTFDRLLISIEN-KTTEIPLIGLIPSCQLEIES----VVNFGTLVANSKVYSKEITITNHGKAPGIFKAEYHGQLP--ILIFPTSGIVDAKSSMVIKVD--FCADQPRIVD----- PIGX_33_PE1 NOISO DKDEDTFDQLLVSVGN-KTIQIPLIGLIPSCQLEIDS----EVNFGTLVADSKVYCKEINIRNRGSLPGKYFVSYKACLE--LQAFPCYGILEGSVLISLQFRKVMLKSRSIDVE----- POEGU1_9_PE4 ISOFORMIN KCAEDLQDKLTLLIDD-DVVHIPVLGLIPYCDLEIES----EVNFGEMIANNKLVTKEISISNRGTISGVFRILYDGVVL--LNIKPARGVVKPKSVRKIKVD--ICTDVPGVIK----- POEGU1_9_PE5 ENSTGUG00000006861 KCAEDLQDKLTLLIDD-DVVHIPVLGLIPYCDLEIES----EVNFGEMIANNKLVTKEISISNRGTISGVFRILYDGVVL--LNIKPARGVVKPKSVRKIKVD--ICTDVPGVIK----- PONPYX_36_PE2 NOISO DKDEDTFDRLLISIEN-KTTEIPLIGLIPSCQLEIES----VVNFGTLVANSKVYSKEITITNHGKAPGIFKAEYHGQLP--ILIFPTSGIVDAKSSMVIKVD--FCADQPRIVD----- PROCAGS_5376_PE1 NOISO ---------------------------------------------------------------------MFIAEYTGELP--ILIYPVSGIVGAKSSVTIRID--FCADQPRIVN----- PTEVAGS_2757_PE1 NOISO XXXXXXXXXXXXXXXX-XXXXXXXXXLIPACQLEIES----EVNFGILVANSKVYCKEIRIINRGKAPGM-TTEYQGLLP----MIPTNGIVEPKSSVIIKVD--FCADQPRVVN----- RABITX_23_PE3 NOISO DKDVDTSDQLHISIGN-KTIVIPLIGLIPYCQLEIES----EVHFGRLVANSKVYCKEINIFNHGRAPGKFDTEYHGQLP--IVIFPTTGIVQPKSSMIIKVD--FCADKPRNVD----- RATX_PE602 NOISO NKNEDTFDHIFISVGN-KVLDIPLIGLIPVCRLEIVP----VVDFGTLVANSKVHCKEITIINRGKAPGMFKTDYQGQLP--IVISPSSGIVKAKSSMVIKVD--FCADQARTVN----- SORARGS_5142_PE1 NOISO DKDEDNHDELVIYIGS-KTLTIPLIGLIPTCQWQVEQ----VIDFGKLVANSKVYCKEVNVFNHGKAPXXXXXXXXXXXXXXXXXXXXXXXX----XXXXXXXXXXXXXXXXXXX----- TARSYGS_6009_PE1 NOISO XXXXXXXXXXXXXXXX-XXXXXXXXXLIPFCLLEIESEIESVVNFGMLVANSKVYCKEIKIINRGRVPGMFKTEYQGRLP--ILISPTSGIVDSKSSIVIKVN--FCADHPRIVD----- XENTR71_2_PE7 NOISO TKKEDIRDRLLVFVDQ-DVINVPLLGFTPSCYLEVDS----EVNFGNIVASSKMIHKEIAIRNHGSSPGTFKIKYTGQLP--ITIAPSSGTVEPKTQQLIRVE--ICTDKPTLFE----- MATCH CONSENSUS DK?ED??D?LLIS????K??EIPLIGLIPSC?LEIES?????VNFGTLVANSKV??KEI?I?NHG??PG?F??EY?G?LP??I?I?P?SGIV?PKSS??IKVD??FCAD?PR?V??????

AILMEGL192953_1_1_PE3 NOISO -EVAKVSLEGHPDILLSVKAHVVEQIIELLNMSNDKKLECIHFGSVFFGTSKIEHALLYNNSPEPINWVAIMQNDSVGEELGTNIQQRTDIALNNL--TYLSKIKNMDVTTFISCVPNEG ANOCA266_2_PE12 NOISO -QPAIVELQGCPSVEVMIKANIVEQIIELFGVPHSNARYCVDFGCVYFGTSKAEEVVLHNKSPEPMHWVAVLQDDAIGTELGTNIQKSTNAVLKDL--HRTGGKPGVDISTLITCNPNEG BOVINUN_004_106_PE1 NOISO -ELAKVSLQDRPDVFLNIRAHVVEQIIELLNINNDKKLECISFGSVFFGTSKIERALLYNNSPEPINWVAIMQDDSVGEELGTNIKQRTDVALNNL--TYLRKIKSIDITTIISCVPNEG CALJAX_36_PE1 NOISO -EKAIVVLQDQPEMLLSIKAYVVEQIIELLHMSHDQRLKCLEFGAVYFGTSKLKHARIYNNSPEPINWVAIIQDDAVGEELGTNTQQRTDIALNSL--ASIRKLKDIDTTTIISCVPNEG CANFAX_32_PE2 NOISO -EVAMVSLQGRPDILLSVKAHVVEQIIELLNMSNDKKLECIHFGSVFFGTSKIERALLYNNSPEPINWVAIMQSDSVGEELGTNIHQKTDVALNNL--TYLRKSKNIDITTFISCVPNEG CAVPO33_24_PE1 NOISO -EVAKVRLQGRPEMYLNIKAHVVDQIIELLNTSDERKLECIHFGSVFFETSKIEHAFLYNNSPQPINWVAVMLNDCVGEELGTNIRQTTDFALNNL--TYLNKIKTIDITTVFSCVPNEG CHICK1_PE1982 NOISO -EMIKVEMEGCTCMEVWIKAVVVEQVLKVLGLPSGNVLECINFGSVYFGSSKIKQISLHNDSPECMDWVAVLEDNAVGGEMGTDLQKSADAVLQDL--SFINKTRDLDVSTFIRCIPDQG CIOIN2Q_6_PE12 NOISO -ETASVQLEGMQDTKLQIKACIVEQSLQLLSQDKQSALSCVSFGPAYYGTDRIEPAYLFNNGPEPLKWVSVLEEGADGEEAGTDLTKSTAAMLATSPMERIRGRAYDILTSLITVLPNQG CIOSAREFTIG_17_1_PE70 NOISO NMHHSVQLEGMQDTKLEIRATIVEQSLQLISHDKRSPLMCVSFGPAYYGTDRIEPAYLFNNGPEPVKWVSVLEEGADGEEAGTDLTKSTAAMLATSPMERIRGRAYDILTSLITVLPNQG DIPORGS_4839_PE1 NOISO -EVARVRLQGRPDILLNIKVHVVEQIIELFNMNNNKKLECIRFGSVFFGTSKIEHAILHNNSPQTINWVAIMEDDSVGEELGSNVPERTDIALNNL--AYLNKIKDIDVTNFISCMPNSG ECHTEGS_9099_PE1 NOISO -EVARVSLQGHSGVILTIKADVVEQIIELLNMSADRRIECIRFGSVFFGTSRIEHALLYNNSPEAINWVAIMQDDAVGEELGTNVRQRTDIALNNL--TYIPKAKAADLTSFISCIPNEG FUGRU36_1_PE11 NOISO -EKAIVKLQNHPA-VLSIRAEVVDQCLELFDLQG-APLSHLSFGPLHFGTSSTKNVVLRNSGPLACDWLCVLQLNAAGTEVGTDLQKRTEAALLEE--MEKCSSFPQDSFPCLLCVPEQG GASACGROUPI_21_PE18 NOISO -EKALLELQNHSDVVLSIKAEVVDQRLEVLDMQD-APLSCLWFGPLYFGTSSVKKVVLRNKSPRACDWVGLLQDTAAGTEAGVDLQKSSDTVLLEG--MERCSPVKPDVSQVLVFVPKQG GORGOX_38_PE4 NOISO -EEAIVILQGQPEMLLNIKAHVVEQIIELLNMSSDRRLECIHFGPVFFGSSKIKHARVYNNSPEPINWVAIIQDDAVGEELGTDIQQRTDIALNNL--TYIRKIKNIDTTIIISCLPNEG HORSEX_30_PE2 NOISO -EVAIVSLQDRPNILLSVKAHVVEQIIELLNMSSDEKLECIHFGSVFFGASKIERALLYNNSPEPINWVAIIQDDSVGEELGTNIQQRTDVVLNNL--TYLRKIKKIDVATFISCVPNEG HSX_PE525 NOISO -EEAIVILQGQPEMLLSIKAHVVEQIIELLSMSSDRRLECIHFGPVFFGSSKIKHARVYNNSPEPINWVAIIQDDAVGEELGTDIQQRTDIALNNL--TYIRKIKNIDTTIIISCLPNEG LAMPAGS_2458_PE1 NOISO -EVAKVSLQDRPDVFLNIKAHVVEQIIELLNMSNGAKLKCIRFGSVFFGASKIEQALLYNNSPEPINWVAIMQDDSVGEELGTNTRQKTVVALNNL--TYLRKIKDIDVTTFISCVPNEG LOXAF82_1_PE10 NOISO -----VSLQGRPDVLLTIKVHVVEQIIELLNMTGDKKLKCIRFGSVFFGTSKIERALIHNKSPEPINWVAIVQDDSVGEELGTNIQQRTDVALNNL--TYLSKIRDIDVTSFISCVPNEG MACEUGS_7203_PE1 NOISO -ELAKVSLQGGEDTFLKIEACVVQQIIELLDICGERSLKCIRFGTIFFGTSKIEQAILYNNSPEHTSWVAVMEHEAVGEELGTNLQQGIDGTLRDL--SYINKMRNIDVTTFIACIPNEG MACMUX_35_PE1 NOISO -LSCRVILQGQPEMLLSIKAHVVEQIIELLNVSRDRRLECIHFGPVFFGSSKIKHARIHNNSPEPINWVAIIQDDAVGEEVGTDIRQRTDIALNNL--TYIRKIKNIDTTTIISCLPNEG MICMUGS_3224_PE1 NOISO -XXXXVNLQGRPDVLLNIKAHVVEQIIELLNMSSDKKLECIRFGSIFFGTSKIEHALLFNNSPESINWVAIMQDNSVGEEVGTNIRQRTDIALNNL--TYLNKIKDIDITALISCVPNEG MONDO4_29_PE1 NOISO -ELAKVSLQGGEGTFLRIEAYIVQQIIELLDMYGEKILKCIQFGTTFFGTSRIEHAIIYNNSPNSMSWVAVMEHETVGEELGTNLQQRIDDTLYDL--CYINKIRSIDVTTIISCIPNEG MOUSEX_PE1109 NOISO -EMARVSLQGCPETFLNIKVRVVEQIIELFHMNSERKLECIRFGSVFFGTSKLEHALLYNNSPESINWVAIMQDDCVGEELGTNIHQRTDIAINNI--SYLNKIKKIDMTDFMSCVPNEG ORNANULTRA222_9_PE12 NOISO -EVAKVRLQGCEDTFLRIEANVVEQVIELLNVYD-DKLECVSFGSVFFGTSKTEQAVLYNKSPEPVMWVAVLEDDAVGEELGIDLQKNTDAALQDL--CFLNRTRDVDVTALISCFPNQG OTOGAGS_5803_PE2 NOISO -EKAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXX PANTRX_36_PE3 ENSPTRG00000021782 -EEAIVILQGQPELLLSIKAHVVEQIIELLNMSSDRRLECIHFGPVFFGSSKIKHARIYNNSPEPINWVAIIQDDAVGEELGTDIQQRTDIALNNL--TYIRKIKNIDTTIIISCLLNEG PANTRX_36_PE4 ISOFORMIN -EEAIVILQGQPELLLSIKAHVVEQIIELLNMSSDRRLECIHFGPVFFGSSKIKHARIYNNSPEPINWVAIIQDDAVGEELGTDIQQRTDIALNNL--TYIRKIKNIDTTIIISCLLNEG PIGX_33_PE1 NOISO -WIVTVSLQDRPEIFLTIKARVVEQIIELLDVNDNKKLKCIRFGSVFFGASKVEDAFLYNNSPEPINWVAIMQDDCVGEEVGTNIRQRTDIALNNL--TYLRKIKNVDITSIISCVPNEG POEGU1_9_PE4 ISOFORMIN -EMMKVELESRGCTEVWIKGVVVEQFLKVLGINCGKVLKCINFGPLYFGTSKTEQIHLYNESPECVDWVAVLEDSAIGGEIVRNSSFYSDAVLHDL--SL--KTKDVDVSTVILCVPNQG POEGU1_9_PE5 ENSTGUG00000006861 -EMMKVELESRGCTEVWIKGVVVEQFLKVLGINCGKVLKCINFGPLYFGTSKTEQIHLYNESPECVDWVAVLEDSAIGGEIGTDLQGSTDAVLHDL--SL--KTKDVDVSTVILCVPNQG PONPYX_36_PE2 NOISO -EEATVILQGQPEMLLSIKAHVVEQIIELLNMSSDRRLECIHFGPVFFGSSKIKHARVYNNSPEPINWVAIIQDDAVGEELGTDIRQRTDIALNNL--AYMRKIKNIDTTIIISCLPNEG PROCAGS_5376_PE1 NOISO -DVAKILQ---RRVLLHVRVRSAEQIMML---TSSDTKDCIRFGCVYFGTSK-ERALLYNNSPEAINWVAIMQNDSVGEELGTNTGQRTDVALNNL--TYINKIRNLDVNSFISCIPNEG PTEVAGS_2757_PE1 NOISO -EVAKVRLQGHPDIFLNIKVHVVEQIIELLNISDDQKLECIHFGFAFFGTSKIEHALLYNNSPEPINWVAIMQNDTVGEELGTNIP-RTDVAVNNL---YLRKIKNIDITNFISCH-NEG RABITX_23_PE3 NOISO -ELAIVNLEGRPTMSFNIKAEVVEQIIELLNISDDKKLECIHFGSIFFGTSKIEHALLYNNSPEPINWVAIMQDDSVGEELGTNIRQRTDVALNNL--TYLRKIRALDVTDFISCIPNEG RATX_PE602 NOISO -EVARVSLQGRPETFLNIKVRVVEQIIELFHMNSERKLECIRFGSVFFGTSKIEHALLYNNSPETVNWVAIMQDDCVGEELGANIHQRTDIALNNL--SYLNKIKKIDMTDFMSCVPNEG SORARGS_5142_PE1 NOISO -XXXXMSLQGQPDIHLNIKAHVVNQVIEVLNINTGKKIKCIDFSFVYFGTSKLEYAYLHNDSPEAVTWVAILQDDTVGEEVATNIRQRTDVVLNNL--SYLSKIRNIDVSNFITCIPNEG TARSYGS_6009_PE1 NOISO -EEAIVSLQDRPDIHLIIKAHVVEQIIELLNMNSNKRLDCIRFGSIFFGTSKIERAVIHNNSPEPLSWVAIMHDDSVGEELGTNIQQGTDVALNNL--NYIRKIKNIDITNFISCVPNEG XENTR71_2_PE7 NOISO -EVAKVKLQGRDEILVKIKGNVVYQVLRLLDVSG-KSLECLHFGSVYFGTSATRQAVIYNDSPETMHWVSVLDDDALGVEMGTDFEESTDAALQKL--DYRSKAEKTQATDMISCLPNQG MATCH CONSENSUS ?E?A?V?LQG?P???L?IKA?VVEQIIELLNM?????LECI?FG?VFFGTSKIE?A?LYNNSPEPINWVAI?QDDAVGEELGTNI?QRTD?ALNNL???Y??KIK?ID?T??ISC?PNEG

AILMEGL192953_1_1_PE3 NOISO RLLPYQKIVVTFCFSPKLMIDGK---KNNDPSHRQDYACFLRFESVGSKDGFLRDDNSK---TI--KSDRFQKVELAVTGTGLPVLLQFEPGKVLNFAPCFMGEHSELLCIMQNRSNSLP ANOCA266_2_PE12 NOISO MLQPYQKIVVTLCFSPRFSWLGS---QGCFP-PRQDYAIFLKFEVVGSKDDFLKALSGD---DIPTKAHNPHQIELGLTGSGLPVMLTFIPGPVVNFMECYMGEHTDIVCMLKNECDALP BOVINUN_004_106_PE1 NOISO RLLPYQKSLISFCFSPKLIIDVQ---K-NDPSHRQDYAVFLRFESVASKDGFLRDDN-Q---II--KSGSFQKIELALTGSGLPVLLQFDPGRILNFAPCFMGGHSEIHCVMQNRSKSLP CALJAX_36_PE1 NOISO TLQPYQKIVIIFCFSPKLTDECK---KDIGPSYKQDYVLYLRFESVGSKDGFLRDDDYK---TI--KSERLQKTELAVKGSGIPVLLQFDPGKVLNFKPCFVGERSEIHFTIQNQCQLLP CANFAX_32_PE2 NOISO RLLPYQKTTITFCFSPKLMIDGK---KNNDPSHRQDYAVFLRFDSVGSKDGFLRDDNSK---TI--KSDRFQKVELALTGSGFPVLLHFDPGKVLNFAPCFMGEHSETLCIMQNRSNSLP CAVPO33_24_PE1 NOISO ILLPYQKIVITFCFSPKLIVESK---MNVDPSHRQDYAVFLRFETVRSRDGFSQDDISE---TV--KSDQFQKVELALTGSGHPVLLHLNPGTIFKFSPCFMGEHSDVVCTIHNQSEFLP CHICK1_PE1982 NOISO TLPPYQKSEVTLCFCPKKFKRAF---VANDPSPKQDYLLFLRFEAAGNLQIPSDG-TTP---C---TKNRPNCTELAVTGSALPVMLTFNPGPVIKFMDCFLGEQTQVLCTLKNESESLP CIOIN2Q_6_PE12 NOISO TIGPYQKIPVNFRFSPRFNSSSVGWEATEKPPPRQDFALFMKFEMVGSNDSFLSELEN-----S--KFYSNKKIEVAIRATAVPVLVNIQPSNTFDFGEILCGDHASALCTLTNESALLP CIOSAREFTIG_17_1_PE70 NOISO TIGPYQKVPVNFRFSPRFNSSTVGWEATEKPPPRQDFALFMKFEMVGSNDSFLEEINNS---GS--PYWSNKKIEVAIRATAVPVLVNIHPSNTFDFGEIFCGDHTSALCTLTNESALLP DIPORGS_4839_PE1 NOISO TLLPYEKIVITFCFSPKLVADRI---KDIGPSHRQDYALYVRFDSVGSKDGFLRDDDYK---TI--QSDRHQKVELALTGSGLPVVLQFDPGNVLHFPPCNMGEHSDLMCIVQNQSKSLP ECHTEGS_9099_PE1 NOISO FLSPYGKIEITLCFSPKLVDDGK---VDIDASHRQDYALFLRFESIGSKDSSLKDYDNE---MS--KNQLFQRLELAVTGSGLPVLLQFDP-KILNFAPCVMGEHSEILCVMQNQSQSLP FUGRU36_1_PE11 NOISO RLAPYEQTTVAVRFSPLSNSST-GES-----GFRQDYCLFLLFESVGSKHGFTNRIGFQ---CL--LSPGKSNVELAVTGTGLPVVLVPHPSHDFDFGHCIEGQQVNLPCVLQNFCPLFP GASACGROUPI_21_PE18 NOISO RLGPYDKTTVAVCFSPMSKSKS-GQRKCHRSTGRQDYCLYLLFESVGSRFGFTHCNGTQQTHTL--TSNSSSSVELAVTGSGLPVSLVPSPTRKFDFLTCATGQRVDLLCVLQNLCPQLP GORGOX_38_PE4 NOISO TLQPYQKTVITFCFTPKLMAVGK---KDIGPSYRQDYVLFLRFESVGSKDGFLRDDDYK---TI--KSERFQKVELALTGTGLPVLLQFDPGPVLNFKPCFMGERSEIQCIIKNQCKLLP HORSEX_30_PE2 NOISO RLLPYQKAVISFCFSPKLIVDGK---KNSDPSHRQDYAVFLRFESVGSKDGFLRDDINK---TI--KSDRCQKLELALTGSGLPVLLQFDTGRVLNFAPCFMGECSEIQCIMQNQSKALP HSX_PE525 NOISO TLQPYQKTVITFCFTPKLMAVGK---KDIGPSYRQDYALFLRFESVGSKDGFLRDDDYK---TI--KSERFQKVELALTGTGLPVLLQFDPGPVLNFKPCFMGERSEIQCIIKNQCELLP LAMPAGS_2458_PE1 NOISO RLLPYQKIIITFCFSPKLISDGQ---MNNDPSHRQDYAVFLRFESVGSKDGFLRDDNSK---TI--KSDRFQKVELALTGSGLPVLLQFDPGN--------------------------- LOXAF82_1_PE10 NOISO TLSPYQKTAITFCFSPKLIYDSK---KDVDPSHRQDYALFLRFESVGSKDGFLRDDDNT---IN--KNDRFQKVELALTGSGLPVALQFDPGMVLNFAPCVMGEHSEVLCIMQNRTKSLP MACEUGS_7203_PE1 NOISO TLLPYQKTVITFCFSPXXXXXXX---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---XX--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX MACMUX_35_PE1 NOISO TLQPYQKTVITFCFTPKLMADGK---KDIGPSYRQDYALFLRFESVGSKDGFLRDDDYK---TI--KSERFQKMELALTGTGLPVLLQFDPGPVLNFKPCFMGERSEIQCIIKNQCELLP MICMUGS_3224_PE1 NOISO ALLPYEKTVITFCFSPXXXXXXX---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---XX--XXDRFQKVELALTGSGLPVLLQFDPGKILNFTPCVMGERSEIQCIIRNQSKSLP MONDO4_29_PE1 NOISO ILLPYQKTVITFCFSPKLYENGK---KYAGSSHRQDYALFLKFEAIESKDPFSKSAKGK---AG--ESHSFHKVELALTGSGVPVLLNFVPGTDLEFTPCFMGQHSDILCRIENQSSLIP MOUSEX_PE1109 NOISO TLLPYQKIVITFCFSPKLVVDTK---KDVGPSHRQDYALFVRFDSVGSKDGFLRDDNSN---TM--KSNRLQKVELALTGSGLPVILQFDPGKSLTFAPCHMGEHSDILCIVKNQSISLP ORNANULTRA222_9_PE12 NOISO TLLPYQKTVVTLCFSPKQLSCGV---RRNEPSSRQDYVLFLRFEAVGSKDGFLKSSNGD---QS--SNTDCHRVELAVTGSGLPVLLNCIPGRILNFVPCYMGESSEIFGVLKNESDSLP OTOGAGS_5803_PE2 NOISO XXXXXXXXXXXXXXXXXLIADVK---KKIDPSHRQDYAVFLRFETVGSKDRFSTDDNYK---TT--KSDRFKKVELALTGSGIPVLLQFEPGKILNFSPCVVGEHSELACIIKNQSKSLP PANTRX_36_PE3 ENSPTRG00000021782 TLQPYQKTVITFCFTPKLMAVGK---KDIGPSYRQDYALFLRFESVGSKDGFLRDDDYK---TI--KSERFQKVELALTGTGLPVLLQFDPGPVLNFKPCFMGERSEIQCIIKNQCELLP PANTRX_36_PE4 ISOFORMIN TLQPYQKTVITFCFTPKLMAVGK---KDIGPSYRQDYALFLRFESVGSKDGFLRDDDYK---TI--KSERFQKVELALTGTGLPVLLQFDPGPVLNFKPCFMGERSEIQCIIKNQCELLP PIGX_33_PE1 NOISO RLLPYQRVLIAFCFSPKLIVDGQ---K-NDPSHRQDYAFFLRFESVGSKDGFLRDDNSK---TV--KSDQLQKVELALTGSGIPILLHFDPGRVFNFAPCFMGGHSEIQCVIQNRSKLLP POEGU1_9_PE4 ISOFORMIN TLQPYEKSLITLCFSLEKLERDF---EVNDISLVQDYVLFLRFETVGKRGDCLQDLS----------GSDSLHVDLALTGSGLPVILTFKPGTVLNFEDCYLGEQTQVVCTMKNESKLLP POEGU1_9_PE5 ENSTGUG00000006861 TLQPYEKSLITLCFNWKRYQ--I---TMNDISLVQDYVLFLRFETVGKRGDCLQDLTLK---P---LRSDSLHVDLALTGSGLPVILTFKPGTVLNFEDCYLGEQTQVVCTMKNESKLLP PONPYX_36_PE2 NOISO TLQPYQKTVITFCFTPKLMADGK---KDIGPSYRQDYALFLRFESVGSKDGFLRDDDYK---TI--KSERFQKMELALTGTGLPVLLQFDPGPVLNFKPCFVGERSEIQCIIKNQCELLP PROCAGS_5376_PE1 NOISO SLLPYRKIPITFCFTPXXXXXXX---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---XX--XXDQFEKLEFALTGSGIPVTVHFDPGRVLNFEPCVVGERSDVLCVIYNLSVLLP PTEVAGS_2757_PE1 NOISO RL-LYQKITITFCFSPKLIADSK---KDNDPSHRQDYAVFLRFDSVGSKDGFLRDDNSK---TI--TSDRFQKLELALTGSGLPVILQFDTGRVLNFAPCLIGEQSDIACVMQNPSKLLP RABITX_23_PE3 NOISO TLLPYQKIVITFCFSPKLIFDGK---NNVDPSHRQDYAVFLTFEFIGSKDGFLRDDNYK---TI--KSDRFQKVELALTGTGFPVVLHFDPARVLNFKPCFMGERSDILCVMQNQSKLLP RATX_PE602 NOISO SLLPYQKIVITFCFSPKLVVDIK---KDVGPSHRQDYALFVRFDFVGSKEGFLRDDNSD---TM--KSNRLQKVELALTGSGLPVILQFDPGKALTFAPCHMGEHSDILCIVKNQSISLP SORARGS_5142_PE1 NOISO KLQPYEKVQLTFCFSPKLLTDDT---KNFDPAHRQDYALFLRFECVGSRDGYLRNDINK---EI--KSDQYNRVELALTGTGLPVLLQFIPGKVFTFQPCLIGGHSDMICTMHNHSRSLP TARSYGS_6009_PE1 NOISO TLLPYQKTVITFCFSPKLIIDGK---KDIEPSHRQDYAVFMRFEFKGNKDGFLRDDNYK---TI--KSDQFQKVELALTGTGLPVVLQFNSGKVLNFTPCFMGERSEIQCIIQNQSKSLP XENTR71_2_PE7 NOISO VLLPFQKTNVTIYFTPKQFNEDN---FYDQFPPQQDYALFIRFEPTGSKDRFLQSQSYH---NV-NKETKKQHVELAVTGSGVPVALSFNPGTLYNFKECFIGEQVDILCSLQNKSLCLP MATCH CONSENSUS TL?PYQK?VITFCFSPKL????K???K???PS?RQDYALFLRFESVGSKDGFLRDD??K???T???KS?RFQKVELALTGSGLPVLLQFDPG?VLNF?PCFMGE?S?I?C???N?S??LP

AILMEGL192953_1_1_PE3 NOISO VMYRFQKTAHFKIDPEKGKIDEGCTQNVTCSFIPHQVGVFKVKQLVEIIGSVADEN--------LQS-SLKPFHQVYLDFKSICKPSTKKVVLKINPGISSLVSNPVGQFVVRD---LPK ANOCA266_2_PE12 NOISO ISYVFHKIAHFNICPEKGNIKAKSNQDVIFSFVPHRVGTFSVKQIVDIIGPVVTKN-------SPPILKMEPFHQIQLSFFGFCKSVTNKVVLKSNPGLTPLVSNATGVFVANK---LDQ BOVINUN_004_106_PE1 NOISO LMYHFKKTAHFKIDPQKGKIDEGCIQNVTCSFIPHQVGVFKVKQFIEIIGSVADEN--------LQSSSLKPFHHIYLYFNSVCKPSTKKVVMKVNPGISPLVSNPTGQFVVKD---LVQ CALJAX_36_PE1 NOISO VIYHFPRNANFKIEPEKGRINEGCMVNVMFSFAPHQLGVFKVKQMIEIIGLVADED--------LQSLSMKPFCHVSLDFNSICKAPTMKVVRKTIPGVSPVIHNPTEKIVVED---LAK CANFAX_32_PE2 NOISO VMYRFQKTAHFKIDPEKGRIDEGCVQNVTCSFIPHQVGVFKVKQLIEVIGTVADEN--------LQSSSLKPFHQIYLYFKSTCKPSTKKVVMKINPGISPLVTNPAGQFVVRD---LPK CAVPO33_24_PE1 NOISO VTYSFPKTAHFKIEPNRGKINEGCIQTVTFSFIPHQVGAFKVKQALELIGPVADKN--------LQSTSMKPFYHITLNFKSLCKPFTKKVVMKANPGISPLVSNPTGQFVAKD---LTK CHICK1_PE1982 NOISO VKFSFRKTIHFKISPEKGKIKKSSTKDLVFSFSPRQIGIFEVKQVIDIMGRELEEN-------CLQLPKTKSIHQIYLSFIAVCKPKPKTIRFRINPGITPMITNATGWFVADD---TGQ CIOIN2Q_6_PE12 NOISO LNIQCKKVAHFNATPVQTKIAPGKTQDIMLSFQPNQAGTFQPLQLLDVLGKVCIATKEEGGSEEVTRLRLTSFQTIPIQLVGTSIAIPKHREPKVNPGITPLVTNETGQFVDVTFDDINK CIOSAREFTIG_17_1_PE70 NOISO LNIQCRKVAHFNVTPAQTKIPPGKTQDIILSFQPNQAGSFQPLQLLDVIGKVCISASENEGCDEVTRLRLTSFQTIPIQLVGTSVAIPKHKEPKVNPGITPLVTNETGQFIDVTFENINK DIPORGS_4839_PE1 NOISO VMYRFQNTAHFTIDPARGKIDEGCIQNVI--FLTHGQIGFKVQQIIDIIGPVADEK--------LESLSMKPFHQIYLEFHSVCKAVTKKVVMKINPGLSPFVSNPIGKFVIKD---LAK ECHTEGS_9099_PE1 NOISO VIYRFQRIAHFKIDPEKGKIDEGCIQNITCSFTPRHIGSFKVKQTIEIIGLVADKS--------LQTLSMKPFHYIHLDFTSVCKPRNKRVLMKINPXXXXXXXXXXXXXXXXX---XXX FUGRU36_1_PE11 NOISO VKFHFRKLAHFSTEPSTGKIPPGQCQDVVLSFDARRTGRLKVHQKLDVLGLVQRDG--NQQTEDITPLKLGCIHTITLNLSAVCCSQTVQLPPKLNPGLTPQVTNPAGQRPNVCYSELSR GASACGROUPI_21_PE18 NOISO VYFRFRKVAHFTTDPSTGTIAAGQCQDVVLSFTARQQGSFQVRQKLDVLGPGVQRG--GNTKEDVTEPVLLCFHTITLNLSAVCRCDTTHLGPKLNPGITPAVTNPTGSLPDVRSSDLSR GORGOX_38_PE4 NOISO VTYHFKKTANFEIDPEKGKITGGGMVDVMCSFVPHQLGVFKVKQMIEIIGLVAEED--------LQSLSVKSFHHVYLAFNSICKASTKKVVMKFDPGILPSIRNPTGKFVVKD---LAK HORSEX_30_PE2 NOISO VTYHFQKTANFKIDPKRGRIDEGCIQNVTCSFIPHQVGVFKVKQLLEIIGLVADEN--------LKS-SMKPFHQIYLHFNSVCKPSTKKVVMKINPGISPLVSNPTGQFVIKD---LAK HSX_PE525 NOISO VTYHFKKTANFEIDPEKGKITGGGMVDVMCSFVPHQLGVFKVKQMIEIIGLVAEED--------LQSLSVKSFHHVYLAFNSICKASTKKVVMKFDPGILPSIRNPTGKFVVKD---LAK LAMPAGS_2458_PE1 NOISO ---------------------------VTCSFIPHQVGVFNVKQFIEIIGSVADET--------LQSSSLKPFHQICLYFSSVCKSSTKKVVMKINPGISPLVSNPTGQFVVEN---LVE LOXAF82_1_PE10 NOISO VIYHFRKTAHFKIDPERGKINEGCMQIVMCSFIPRQVGTFKVKQVIEIIGLVADEN--------LQSLSMKPFHHIHLDFNSVCKPFTKEVVMKINPGISPLVSNPTGQFVVKD---FAK MACEUGS_7203_PE1 NOISO XXXXXXXXXXXXXXXXXXXXXXXXXXNVLFSFVPHQLGIFKVKQLMDILGFVAEDD--------LQSVKVKPFHQIQLSFTSICKPTTKRIEMKIIPGLTPLITNSTGQYVVDE---AGE MACMUX_35_PE1 NOISO LTYHFEKTANFKIDPEKGEINEGGMVDVMCSFVPHQLGVFKVKQKIEIIGLVAEKD--------LQSLSIKPFYHMYLNFNSICKASTKKVVMKFDAGMLPLIRNPTGNFVGKD---LAK MICMUGS_3224_PE1 NOISO VMYHFKKTGNFKIDPERGTINEGCSQNVICSFIPHQIGIFKVKQLVEIIGLVADEN--------LLSLSMKPFHHIYLDFNSICKPATKKVVMKINPGISPLVSNPTGQFVAKD---LAK MONDO4_29_PE1 NOISO VTFSFHKVAHFKIIPEKGKIDEGSNQNVLFSFVPHQLGMFKVKQLIDILGSVAEDD--------FQSVKVKPFHQIELNFTSICKPITKRIEMKVIPGLTPLITNSTGQYVVDE---TGQ MOUSEX_PE1109 NOISO VMYHFKKTAHFKMDPERGKIDEGCIQNVICSFVPHQIGVFKVKQVIEIIGPVADDN--------LRSLSMKPFLYIHLNFSSTCKAFTRKVGVKINPGISPLISNPTRHFVAKD---SEK ORNANULTRA222_9_PE12 NOISO VIFNFHKIAHFKTNPEKGKIEIRNTQDVQFSFVPHQVGIFKVKQVVDIIGSVATED-------NSPCLKMKPFHQIHLCFTGVCRPITKKIELKIHPGLAPLTSNTTGQAFMDE---MEK OTOGAGS_5803_PE2 NOISO VTYNFKKSAHFKIDPEKGKIDEGCIQNVLCSFIPHQIGVFKVKQVIELLGLVADEN--------RQSALMKPFYHVYLEFNSICKPSIKNDRMKITPG--------TGQFVIKD---LDT PANTRX_36_PE3 ENSPTRG00000021782 VTYHFKKTANFEIDPEKGKITGGGMVDVMCSFVPHQLGVFKVKQMIEIIGLVAEED--------LQSLSVKSFHHVYLAFNSICKASTKKVVMKFDPGILPSIRNPTGKFVVKD---LAK PANTRX_36_PE4 ISOFORMIN VTYHFKKTANFEIDPEKGKITGGGMVDVMCSFVPHQLGVFKVKQMIEIIGLVAEED--------LQSLSVKSFHHVYLAFNSICKASTKKVVMKFDPGILPSIRNPTGKFVVKD---LAK PIGX_33_PE1 NOISO VMYNFKKTAHFKIDPQRGKIDEGCMQNVTCSFIPHQVGVFKVKQFIEIIGSVADEN--------LQSSSLKPFHQICLYFNSVCRASTRKVVMKINPGISPLVSNPTGQFVVKD---LAK POEGU1_9_PE4 ISOFORMIN LMFRFRKTAHFSVSPARGKLKKNSEKEVVISFSPHQIGTFEMKQIIDIVGMGVDKS-------NVAVLKTKPFHQIYLTLLGVCKSKQTSVVFTINPGLTPLISNATGQFVVRG---TGQ POEGU1_9_PE5 ENSTGUG00000006861 LMFRFRKTAHFSVSPARGKLKKNSEKEVVISFSPHQIGTFEMKQIIDIVGMGVDKS-------NVAVLKTKPFHQIYLTLLGVCKSKQTSVVFTINPGLTPLISNATGQFVVRG---TGQ PONPYX_36_PE2 NOISO VMYHFKKTANFEIDPEKGEINGGGTVDVMCSFVPHQLGVFKVKQMIEIIGLVAEED--------LQSLSVKSFHHVYLAFNSICKASTKKVVMKFDPGILPSIRNPTGKFVVKD---LAK PROCAGS_5376_PE1 NOISO VTYRFKKTAQFKMDPESGTIETAGSQDVVCSFIPHQIGNFKVEXXXXXXXLVANPD--------VLSVSMKPFSSIYLEFKGMCRSSIKKIAMKVNTGLTPLVSSPVGQFVVKE---PPA PTEVAGS_2757_PE1 NOISO VMYRFKKTAHFKVDPEKGKVDEGCMQNVVCSFIPHQVGVFKVKQFIEIIGPVADEN--------FRSLSLKPFHQIHLVFNSVCKPSAKKVTMKINPGISPFVCNPTGQFVVKD---LAK RABITX_23_PE3 NOISO VKYHFEKVAHFKVDPERGKIDEGCIQNINCSFIPHQIGIFKVKQPIAIIGPVVDEN--------LQV-SMKIFHHVYLEFSSICKASTKKVVMKINPGISPFVSNPTGQFVVKD---LVK RATX_PE602 NOISO VMYHFQKTAHFKMDPERGKIDEGCIQNVICSFVPHQIGVFRVKQVIEIIGPVADDN--------LQSLSMKPFHYIHLEFNSTCKAYTKKVGVKINPGISPLVSNPTKHFVAKD---SEK SORARGS_5142_PE1 NOISO VSYQFKKAAHFKINPKKGKIDEGCNQVVTCSFIPHQIGIFKVKQIIEIIGLVANED--------FQSTTLKPFHEMNLYFNSVCKPSTTEVVMAINPGLSPLVSNPTVRYVTKD---VVN TARSYGS_6009_PE1 NOISO VLYHFKKTAHFKVDPKRGKIDEGCTQHVMCSFIPHQVGFFKVKQVIEIIGSVADEN--------LQSLSMKPFYHIYLDFNSICKPSRKKVVMKINPGISPLVSNPVGQFVVED---LAK XENTR71_2_PE7 NOISO VVFSFCKISHFYISPAKGKIEPGHSQDVMLTFSPHQVGTFRVKQVVDILGPTTEDN--------LPALKTNVFHQKTLIFHAVCNPVSKRIVMKINPGITPKVSNATGQFLAAAQE-TAM MATCH : * .. : : : : . . . CONSENSUS V?Y?F?KTAHFKIDPEKGKI?EG??Q?V?CSF?PHQ?G?FKVKQ?IEIIG?VADE?????????LQSLS?KPFH?IYL?F?S?CK??TKKVVMKINPGI?PLVSNPTGQFVVKD???L?K

AILMEGL192953_1_1_PE3 NOISO YKYRAPV-TMLQSAMTSLHNHRRGKE-SMKGALIAFPNDRAASIRSGDQHKLF---RTIFTKIPRYNYVDPDFAYTKFEKIKKQAHENYYAEYIKHLRSVRLRKQA-ERECMY---SYND ANOCA266_2_PE12 NOISO HSDITPI-ALLKSNRTQIHAHQIKKN--MSKAILALPNDRAGSIRPAELHKDY---RTIFTKVPRYSYVDPEFSYTTFEEAENQEHKEHYADYLRSLRQRRFYKKA-ARIFTM---LNNP BOVINUN_004_106_PE1 NOISO YKDHARV-AMLQSTMTRIHNHKINKE-LLKDALIAFPNDRAASIRSGEDHENF---RTIFTKIPRYNYVDPDFAYTKFEKIVKKSHDNYYVEYIKFLRNVRLQKEA-HRKHIY---SYND CALJAX_36_PE1 NOISO CKTYAPL-SVFKSTIRCTHNHHSRGE-SEKDMLLPFPKDGAATIGCTDHHKHF---RGTFITVPRFNFVNHDFACTTCEKQQRKYHAKNYSTYLKYLRNIHLQK-QAEREKTY---SYND CANFAX_32_PE2 NOISO YKDRAPV-AMLQSTMTRLHNHRLCKE-SMKDALIAFPNDRATSIRSEDQDKIF---RTIFTKIPRYNYVDPDFAYTKFERIKKQSHGNYYAGYIKHLRSVRLQKQA-ERECMY---SYND CAVPO33_24_PE1 NOISO YKDFAPV-AKLQSSRTHLHDYQSKNE-SMKGALMAFPNERAASVRPGERYEVF---RTIFTKVPRYTYIDPDFEYTELEKIEKRVHQDYYSNYIKFLRQNRLQKEAASRKCAH---SNNA CHICK1_PE1982 NOISO CTDTAPM-AILKSTKTQIHTHQINRN-CKRDALIAFPNDRSTSIRPSERNKKY---RTIFTKTERYNYVDPEFSYTDYEILSKKVHKEYYADFISGLRQHRLQKDATRDFHTIFSPSRHN CIOIN2Q_6_PE12 NOISO VKGQLRT-TIVNSANAKLHLQGGDKV---KKALVAFPNDRAQSIRPSKRDEEY---QTPFTRSKRHTYVDPDYAYTIEEENARKQHKDKYTHFLRECTDKRVRKEQ-TREYKE---INND CIOSAREFTIG_17_1_PE70 NOISO VKGQLRT-TIVNSANAKLHLHDGDKK---KKALVAFPNDRAQSIRPSKRDDEY---QTPFTRSKRHTYIDPDYAYTVEEEASRKQHRDKYTQFIREATDTRVRKEQ-TKAYKE---INNP DIPORGS_4839_PE1 NOISO NKNPVPV-AMLQSATTCLHNHHINEK-STANALIAYPNDRPGSIRPGDHHKTF---RTIFTKTPRHNYIDHEYEYTSLEQEKKKAHQDYYTKYIRNSRNIRLQKEA-ERQHMC---SHND ECHTEGS_9099_PE1 NOISO XXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXXXXXXXXXXXXXXXX---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNSKY---SYDD FUGRU36_1_PE11 NOISO CYTMVHA-AVLRADKTQLHEHQRKSQNTNEKVFLAFPNDRATSLRPADADTEY---RTIFTGVRRYHYIDTTFAFTEEEEKQRQQHKQIYMNFLSRRRQTYLQKIK-ESKQD----KITD GASACGROUPI_21_PE18 NOISO CRATLPV-AVLGAGRTLLHKHRRRRP--EGEEFLAFPNDRPASNRPASAHRQYSSLRTLFTGVQRYCYVDTSYAFTEEEEEQRRRHRKIYADFTRQLGKTRLQETD-ERQQKA---VEND GORGOX_38_PE4 NOISO RKNYAPV-AMLQSAMTRTHNHRSCEE-PVKDMLLAFPNDRAATIRSKDHHKHF---RPIFTKVPRFNYVNHDFAYTTFEKQQKKLHENYYAMYLKYLRSVRLQKKQAERERMY---SYDD HORSEX_30_PE2 NOISO YKDCLPV-AVLQSAMTHIHDHRSSKK-AMKDALIAFPNDRIASIRSGEQDKHF---RTIFTKIPRYNYVDPDFAYTELENIEKKAHDDYYTRYIKCLRNVRLRKQA-EREHMY---SYND HSX_PE525 NOISO RKNYAPV-AMLQSAMTRTHNHRSCEE-PVKDMLLAFPNDRAATIRSKDHHKHF---RPIFTKVPRFNYVNHDFAYTTFEKQQKKLHENYYAMYLKYLRSVRLQKKQAERERMY---SYDD LAMPAGS_2458_PE1 NOISO YKDHAPV-AMLQSTATQIHNHSTNKQ-LIKDAMIAFPNDRAASIRSGDEHTHF---RTIFTKIPRYTYVDPDFAYTEFEKIDKKAHENSYTGYIKYLRNVRLQKQA-QRKHTY---SYND LOXAF82_1_PE10 NOISO CKDYAPV-AMLQSAKARIHSHEASKD-TVKDALIAFPNDRAASIRPGEQGKHF---RTIFTKIPRYNYVDPDFAYTKIEELEKRVHQNYYEKYIKCLRSVRLQKQA-ERESRY---SYDE MACEUGS_7203_PE1 NOISO YKNFAPV-AMLKSNLTSIHNHHLSEP-LGDDVLVAFPNDRCASLRSGDHQVLC---WTIFTKVPRYNYVDPEFAYTKEEEIQIQENKDHYKLHPEW--QSVMQRKS-ARQGIY---SDNE MACMUX_35_PE1 NOISO RKNYAPV-AMLQSATTRTHNHRSCEE-PVKDVLLAFPNDRAATIRSKDHDKHF---RPIFTKIPRFDYVNPDYAYTALEKQRNKLHENYYALYLKYLRSVRLQKKQAKREHMY---SYDD MICMUGS_3224_PE1 NOISO YKDSAPV-AMLQSAKTYIHNHRSNKE-SVKDELIAFPNDRTASIRSGDHDKHF---RTIFTKIPRYNYVDPDFAYTEFEKMEKKAHNYYYAMYIKYLRNVRLQKQA-ERECMS---SRND MONDO4_29_PE1 NOISO YKNFAPV-AMLQSHITSIHNHRLSKN-LNKDALVAFPNDRSASLRSGDPRVEI---RTIFTKVERYNYVDPEFAYTKEEQKQINENKDYYANFTNNLAKQRMLRKS-EREFKR---SDNA MOUSEX_PE1109 NOISO KDDLPPVAAMLQSTATKLHDHCLKDE-STKNALIAFPNDRATSIRSGDHHEHF---RTIFTKIPRYDYTDPDYEYTDLEKLERKAHRDYYTNYINNLRTIRLRKEA-QRERKF---PVNE ORNANULTRA222_9_PE12 NOISO YKKLAPV-AILQAAQTKIHSHQRRKD--SKNVLIAFPNDRSGSIRSGERYKTF---RTVFTNADRYNYVDPSFAYTHSEEIKRKANQDIYFNYIQSLRNQRQQKEKASREFIL---LNNA OTOGAGS_5803_PE2 NOISO YKESAPI-AMLQSNKTSLHTHQSNQW-SRKDELIALPNDRSGSIRPGDHRKHF---RTIFTKTPRYNYVDPDYAYNELEKEM--KHDNYYTMYKHL--SVRLN--KKERESMY---PYND PANTRX_36_PE3 ENSPTRG00000021782 RKNYAPV-AMLQSAMTRTHNHRSCEE-PVKDMLLAFPNDRAATIRSKDHHKHF---RPIFTKVPRFNCVNHDFAYTTFEKQQKKLHENYYAMYLKYLRSVRLQKKQAERERMY---SYDD PANTRX_36_PE4 ISOFORMIN RKNYAPV-AMLQSAMTRTHNHRSCEE-PVKDMLLAFPNDRAATIRSKDHHKHF---RPIFTKVPRFNCVNHDFAYTTFEKQQKKLHENYYAMYLKYLRSVRLQKKQAERERMY---SYDD PIGX_33_PE1 NOISO YKDHAPV-AMLQSTMAEVHNHIKSKE-LLKGALIAFPNDRAASIRPGDEHEHF---RTIFTKIPRYNYLDPDFAYTELEKIEKKAHENYYARYIKYLRNVRLQKQA-QRKCIY---SFDD POEGU1_9_PE4 ISOFORMIN LSDTAPV-AILKSTQTQIHTHRKNRS-CEDDALIAFPNDRAASLRPSEWNKKY---RTIFTKTERYNYIDPEYAYTHSEQLLREENKKHYVQFISCLRQRRLEKNA-------------- POEGU1_9_PE5 ENSTGUG00000006861 LSDTAPV-AILKSTQTQIHTHRKNRS-CEDDALIAFPNDRAASLRPSEWNKKY---RTIFTKTERYNYIDPEYAYTHSEQLLREENKKHYVQFISCLRQRRLEKNAIGQFCIYN----NP PONPYX_36_PE2 NOISO RKNYAPV-AMLQSAMTRTHNHRSCEE-PVKDMLLAFPNDRAATIRSKDHHKHF---R----------------------------------------------------ERMY---SYDD PROCAGS_5376_PE1 NOISO EEEPTPA-EMPESEEAPIPIEEAKEE--AEESQVAVPSEPAPSTKPAKQGKNF----TVFRKTPRYNYVDEEYAYTKIEELKKKLHQNCYEYYLKDLRSARLQKQA-ERESRY---SYDD PTEVAGS_2757_PE1 NOISO YEEYAPV-AMLQSAMTTIHNQCSNKE-AVKDALIAFPNDRAASIRPGHPDKHF---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLGKY---VYDD RABITX_23_PE3 NOISO NKNPVPV-AMLQSALTDLHNHHSNKA-SVKNALIAYPNDRTASVRPGAQDKHF---RTIFTKIPRYNYLDPDFACTDVEKFIKKANEYYYINYIRDRRNLCLKKQA-EREHKN---LYND RATX_PE602 NOISO KEDLLPVAAMLRSTATNLHNHCSNDE-SMKNALIAFPNDRAASIRCGDHHEHF---RTIFTKMPRYDYTDPDYEYTDLEKLERKAHRDYYTNYINNLRTVRLHKEA-LRERKL---LVNE SORARGS_5142_PE1 NOISO RKESTRA-AMLQSALTPIHDHRSAKEYSAKDALIAFPNDRAASIRPGDH-KNF---RTIFTKIPRYSYVDPEFEYTDLEKLEKGLHKNYYARYINYLRNMRIQKQA-------------- TARSYGS_6009_PE1 NOISO SKDSAPV-AMLQSAMTSIHNHHSSKK-SMKDALIAFPNDRAASIRSGDHHKNF---RTIFTKIPRYNYVDPEFEYTEFEKLEKKSHEIYYANYIKYLGNVRLQQ-A-ARERKY---SYND XENTR71_2_PE7 NOISO YIGHTSV-AALSSNKTHIHNHQKKDD---NEELVAFPNDRAASIRPSDSSTKY---RTLFTKVERYNYVDPDYAYTEEEEKLRKSHKDYYINYIQSIREERLKREK-EREFED---VNNP MATCH CONSENSUS ?K??APV?AMLQS??T??HNH????????KDALIAFPNDRAASIR?GD??K?F???RTIFTK?PRYNYVDPDFAYT??E???KK?H??YY??YI??LR??RLQK?A??RE??Y???SYND

AILMEGL192953_1_1_PE3 NOISO TDIGLQPASGLKSPSLSETEIEEELCS-AKC-QIEPNQLLNTRNIESEETKALKRKV--LKGLKSDPSTPHEKHDCSLILTPKQIHQVIVGPSVLNFGDVCVNSTNTRLLHVINMLPMHI ANOCA266_2_PE12 NOISO VDIGLKPAHGLKSPKVKDLPQEKTKQD-V--TCITGSNMLTSQQLVEIKAKSVDKEV--SEGLNPVPCSPQEIEDCSLILTSRQLRQVFIGPSTIDFGEVCVHSSSSQKLHLINNLPVHI BOVINUN_004_106_PE1 NOISO IDIGLHPASGLKSPTVSEVEREEELPS-TQY-WIKHNQLLRTRNI