Alignment of the gene Family HOG000054225 of HOGENOM

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Threshold: 50% 80% 100%
Size: Bigger Smaller Normal
Isoforms are ON
AILMEGL194206_1_PE15 NOISO APESCQEAKEAEKEAPLSLVGQEPVNGHLQPPAGTPQEAVAPSCPQDIKPSST-RVVFSV CALJA11_136_PE63 ISOFORMIN -----------WARPGG---DRESVSGHLGPPAGTPAASATS---------MT-RVACSA CALJA11_136_PE64 ENSCJAG00000012183 ----------RWLKPAGGSRDRESVSGHLGPPAGTPAASATS---------MT-RVACSA CANFA18_29_PE29 NOISO ---------LHWPAARRRRPGQALVNGPRERPAGTLQDPVAPKCPQDTKPSSS-RVVFST CAVPO218_PE25 NOISO -------KRPVWPGGR--GRGRQPVGNDSGPPTTIPTDTMASSCSRNRRPPSTG--EGSI DIPOR17830_PE2 NOISO ------AQ-PRPSAAV--RRHGEPASSDVGPPVDTPTDKGNPS---RSQDTTSQ--PPVV FELCAGS_4243_PE8 NOISO --------VRPWPPG---GRHEEPVSDHPEPPAGPPKDPVAPACLKDTKPSST-PVVFPV GORGO11_1_PE32 NOISO ---------IRWLRPAGRRREQESVSGHLGPPAGAPAAPETPTCLPDTTPHPA-PVVCSA HORSE12_33_PE10 NOISO --------------------DQELVSGHLGPAASTPAGPVAPTCPQDTKPNST-RMVSST HS11_PE61 ENSG00000185522 ---------MRWLRPAGRRREQESVSGHLGPPAGAPAAPETPTCLPDTTPHPA-PVVCSA LOXAF227_PE2 NOISO APKFHQDAEEAEEEMLSSLVDREQVHGGLGSPAGAVVNPVAPTGQQG-TKPQS-SQIFPV MACMU14_1_PE31 NOISO -------------EALLSPTERESVSGHLGPPAGAPAAPETPTCLPDTTPHPT-RAACSA MONDOUN_47_PE11 ENSMODG00000011024 ------------------------------------------------------------ MOUSE7_PE3945 NOISO APKSCQESEDKQVSPA--PAGVQPDSSDLGSPVGTPVDRVAPSYSQSAKLYTSTPMGCSV OCHPRGS_3375_PE2 NOISO ------ARRPRPAGRCVPRRGQE--------TSWGPQPTGLPTSQQDTKPVSP-PGAASA PANTR11_1_PE29 NOISO ---------MRWPRPAGRPREQESVSGHLGPPAGAPAAPETPTCLPDTTPHPA-PVVCSA PONPY11_1_PE16 NOISO --------------------EQESVSGHLGPPAGA--APETPTCLPDTTPHPA-PVVCSA PROCAGS_4986_PE2 NOISO --------------ARRGGWVRAAGHDGLGPAATAATDPVAPTGQQDEDEPQS-PPTFSI PTEVAGS_2542_PE2 NOISO ----------ARLGRPGGRLDREPVSGHLPASTADLV----APAGKDTKPSYK-GVVFPL RAT1_PE3030 NOISO APKSCQESEDEQVSPA--PAGVQPDSSDLGSPVGTPVARVASSCPQSAKLYTSTPMNCSV SPETRGS_3814_PE2 NOISO ------ARLQPGSEGG--PSDGEPVSSDLGLPAGTPTDTVVRPCPQNTKTHSTR--LASV TUPGBGS_3661_PE2 NOISO --------EPLWPEFAGGGRDQQPH------SALAPLAPMASTCPQNTKPHST-RMGVST TURTR103543_PE3 NOISO ------------ASQTAGRRRDRDVSGHVGPASASPD-RGAPACPQDTKPSST-RMVSSV MATCH CONSENSUS ????????????????????????????????????????????????????????????

AILMEGL194206_1_PE15 NOISO NLQSAPESLDPRTLRLLWRQRDLEIQALRWAIQNHHDARHCHVLHEVAGLPPERSACNQE CALJA11_136_PE63 ISOFORMIN NPQLAPESLDPRTLRLLWGQRELEIQALRWAVRNGRDTRLWHILQEVAGLPPKRSSHSQE CALJA11_136_PE64 ENSCJAG00000012183 NPQLAPESLDPRTLRLLWGQRELEIQALRWAVRNGRDTRLWHILQEVAGLPPKRSSHSQE CANFA18_29_PE29 NOISO NLQLTPESLDPRALRLLWGQRELEIQALRWAIQNRPDARHCHVLQEVAGIPPERGARNQE CAVPO218_PE25 NOISO STQLAPETLDPCTLRLLWEQRELEIQALRWAIRHGQHAQHHHILQEVAGLPPERSSHSQD DIPOR17830_PE2 NOISO NLQLSPEALDPRTLRLLWQLRELEIQSLRSALQN---DRHCHILQEVAGIPPERSPCTQE FELCAGS_4243_PE8 NOISO NLQLAPESLDPRTLRLLWGQRELEIQALRWTIRNRQNARRCHILYEVAGLPPESCSHSQE GORGO11_1_PE32 NOISO DPQLALESLDPRTLRLLWRQRELEIQALRWAVQNGEDAWLCHILEKVAGLPPKRSSHSQE HORSE12_33_PE10 NOISO NPKLAPESLDPRTLRLLWGQQELEIQALRWAIQNSWGPQHCRILQEVAGLPPERSLCRQQ HS11_PE61 ENSG00000185522 DPQLALESLDPRTLRLLWRQRELEIQALRWAIQNGEDARLCHILEEVAGLPPKRSSHSQE LOXAF227_PE2 NOISO NLRAAPESLDPRTLRLLWGQRELEIQALRWAVQGSRDGRYYRILQEVAGLPPERSYQSQE MACMU14_1_PE31 NOISO DLQLALESLDPRTLRLLWKQRELEIQALRWAVQNGKDTRLCHILEEVAGISPKRSAAQSP MONDOUN_47_PE11 ENSMODG00000011024 ---MHLEHANPRLLKLLLAQRDLEIQSLREAARCPAGKRMNYILRVLTDAKPDRAPQDQL MOUSE7_PE3945 NOISO KQQLAPETLDPRTLRLLWEQRELEIQALRWAVQNGHNARYSSILQEVAGVPSERNSKSQD OCHPRGS_3375_PE2 NOISO TLHLAPETLDPRTLQLLWGQRELEIQALRWAVKNGCNTQHQRVLQEVAGFPPQXXXXXXX PANTR11_1_PE29 NOISO DPQLALESLDPRTLRLLWRQRELEIQALRWAVQNGEDARLCHILEEVAGLPPKRSSHSQE PONPY11_1_PE16 NOISO DPQLALESLDPRTLRLLWRQRELEIQALRWAVQNGQDAWRCHILEEVAGLPPKRSSHSQE PROCAGS_4986_PE2 NOISO NSQAAPESLDPRTLRLLWGQRELELQALRWTVQGGRTARSHHILQEVAGP--ETSSRNWE PTEVAGS_2542_PE2 NOISO KLHLAPESLDPRTLKLLWRQRELEIQALRCAIQEPQSARRGRILQEVAGLPFERSPHSQK RAT1_PE3030 NOISO KQQLAPETLDPRTLRLLWEQRELEIQALRWAVQNGQNARYYYILQEVAGIPPERNSKRQD SPETRGS_3814_PE2 NOISO HLQLAPEALDPRTLRLLWEQRELEIQALRWAIRNGPHARHCHILQEVSGLPSERSFHSPD TUPGBGS_3661_PE2 NOISO NTRLAPESLDPHTLRLLWGQRELEIQALRWAVQNGQDARHCHILQEVAGLLPERSSRNQE TURTR103543_PE3 NOISO NPQSAPESLDPRTLRLLWRQRELEIQALRWAIENHREARHCRILQEVAGLPAERSSCSR- MATCH * :* *:** ::**:*:** : . :* ::. . CONSENSUS ????A?E?LDPRTLRLLW?QRELEIQALRWA???????????IL?EVAG?P??R??????

AILMEGL194206_1_PE15 NOISO KVLQNQVQKLTVQLKEQKEQAQLQEKSQLEERLLQTMTTMQQLEAELQAFQKSCLLQLAR CALJA11_136_PE63 ISOFORMIN RLLQSQVQKLTLQLKEQKEQAQW-EKEYLEEQLLETTRRLQEVEAELQNFQKSCLLQLAR CALJA11_136_PE64 ENSCJAG00000012183 RLLQSQVQKLTLQLKEQKEQAQW-EKEYLEEQLLETTRRLQEVEAELQNFQKSCLLQLAR CANFA18_29_PE29 NOISO RFLQNKVQKLTLELKKQKEQAQL-EKSQLEERLLQTATTIQQLEAELQAFQK-CPLQLAR CAVPO218_PE25 NOISO TFLQNQVQKLTLELRAQKEQAQL-ERECLEAQLAQTTDKLQQLEAELQAYQKSCLLHLAQ DIPOR17830_PE2 NOISO KFLQNQVRKLTLDLKAQKEQARL-EKELLEKQLMQTLHMVQQLEDELQNFQKSCLLHLAH FELCAGS_4243_PE8 NOISO KLLQNQVQKLTLELKGQKEQAQLEK---------------SQLETELQAFQRSCLLQLAR GORGO11_1_PE32 NOISO KLLQNQVQKLTLELKEQKERAQW-EKEHLEERLLQTTRTLQEVEAELQNLQNSCLLQLAH HORSE12_33_PE10 NOISO KFLQNQVQKLTLELKEQKEQAQL-EKAQLEEQLLQTMNTLQQMEAELQGFQKSCLLQLAQ HS11_PE61 ENSG00000185522 KLLQNQVQKLIQELKEQKERAQW-EKEHLEERLLQTTRTLQEMEAELQNLQKSCLLQLAR LOXAF227_PE2 NOISO KFLQNQVQKLTLELKEQKKQARL-EKEQLEQQLLQTLETVRQLEVELQTFQKSCLLQLAR MACMU14_1_PE31 NOISO TNPT-----------------------------------------------LPC---PRP MONDOUN_47_PE11 ENSMODG00000011024 KDLQQQMEKMTEELKGQKERADQ-EKLELEAQLKEAKATMQQLEDELLSFQRSCLLHLAR MOUSE7_PE3945 NOISO KFLRNQVQKLTLELKAQKEQAQQ-EKQQLEEKLQQNLWAKQQLEAELQTFQKSCLLQLAR OCHPRGS_3375_PE2 NOISO XXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX PANTR11_1_PE29 NOISO KLLQNQVQKLTQELKKQKERAQW-EKEHLEERLLQTTRTLQEMEAELQNLQKSCLLQLAR PONPY11_1_PE16 NOISO KFLQNQVQKLTLELKEQKEQAQW-EKEHLEERLLQTTRTLQEVEAELQNLQKSCLLQLAR PROCAGS_4986_PE2 NOISO KVLQNQVQKLTLELREQKGRAQL-EKEHLEQRLRQAVERLQQLEAELLTLRRSCLLKLAH PTEVAGS_2542_PE2 NOISO KLLQTQVQKLTLELKEQKEQAQL-EKAHLEEQLMQTKQLLQQVEAELQALEKSCLLQLAR RAT1_PE3030 NOISO KFLRNQVQKLTLELKAQKEQAQQ-EKQQLEEKLQQNLCAMQQLEAELQSFQKSCLLQLAR SPETRGS_3814_PE2 NOISO KFLQEQVEKLTLELKAQKEQAQL-EKEHLEEQLMQTVSMLQQLEAQLQAFQKSCLLQLAC TUPGBGS_3661_PE2 NOISO KFLQSQIQKXXXXXXXXXXXX-XXXKQHLEEQLRLTTSTLQQLQAELQTFQKSCLLQLAR TURTR103543_PE3 NOISO KLLQNQVQKLTLELEEQKGQAQL-EKAHLEERLLQTRNTLRQLEAELQALQKSCLLQLAR MATCH CONSENSUS ??LQ?QV?KLT??L??QK??A???EK??LE??L??????????E?ELQ??Q?SCLL?LA?

AILMEGL194206_1_PE15 NOISO HSWVGRILRSSTGSVEVVTAETLMDFSDLSESEQGPSTGEGFRLEDVDWNSIAQRYPNLF CALJA11_136_PE63 ISOFORMIN SSWVGRMLQSQTGSVEVVMAGTLMDPSDLSENIQAP-TGEGFRLE-KDWNSIARRYPNLF CALJA11_136_PE64 ENSCJAG00000012183 SSWVGRMLQSQTGSVEVVMAGTLMDPSDLSENIQAP-TGEGFRLE-KDWNSIARRYPNLF CANFA18_29_PE29 NOISO SLWVGRILRSSTGSVEVVTAETLLELSDLPESAQGPSAGEGFRLEDVDWNSIAQRYPNLF CAVPO218_PE25 NOISO SSWVGRIIRSQTGSVEVITAETLMESGDSEDN-QEPTAGEGFRLEDVDWNSIAQRYPNLL DIPOR17830_PE2 NOISO SSWVGRILRSQTGSVEVITAETLMEPSDFSEN-E--QTGEGFRLEDVDWNSIARRFPNLL FELCAGS_4243_PE8 NOISO SSWVGRVLRSSTGSVEVVTAETLMDSSDLSENDQVPSTGEGFRLEDVDWNSIAHRYPNLL GORGO11_1_PE32 NOISO SSWVGRMLRSQTGSVEVVTAETLMDPSDLSENIQAP-TGEGFRLEDVDWNSVARQYPNLF HORSE12_33_PE10 NOISO SSWVGRVLRSSTGSVEVVTAETLMDFSDFSENGNISASGEGFRLEDVDWNSIAHRYPNLF HS11_PE61 ENSG00000185522 SSWVGRMLRSQTGSVEVVTAETLMDPSDLSENIQAP-TGEGFRLEDVDWNSVARRYPNLF LOXAF227_PE2 NOISO SSWVGRILRSQTGSVEVVTAETLMDPSDSSENELVP-AGEGFQLKDVDWNSVAQRYPNLF MACMU14_1_PE31 NOISO DSWF---------------------------------------LSDPNPNHLPSSSPTL- MONDOUN_47_PE11 ENSMODG00000011024 TSWAGRVLRSQTGSVEVVTAQALMMDVSDESLELSSSEGQHFRLEDVDWNSVAHRYPNLF MOUSE7_PE3945 NOISO SSWVGRVLRSQTGSVEVVTTEVLRDPSDFSESAEIPTSGEGFPLEDVDWNSIAQRYPNLF OCHPRGS_3375_PE2 NOISO XXXXXXXXXXXXXXXXVVTAETLREPSDMEDSDPALGSREGFRLEDTDWNSIARRYPNLF PANTR11_1_PE29 NOISO SSWVGRMLRSQTGSVEVVTAETLMDPSDLSENIQAP-TGEGFRLEDVDWNSVARRYPNLF PONPY11_1_PE16 NOISO SSWVGRMLRSQTGSVEVVTAETLMDPSDLSENIQAP-TGEGFRLEDVDWNSIAHRYPNLF PROCAGS_4986_PE2 NOISO SSWVGRILRSQTGSVEVVTAETLMDPSDSSETELVP-VREGFQLKDVDWNSIAQRYPNLF PTEVAGS_2542_PE2 NOISO SSWIGRMLRSSTGSVEVVTAETLIDPSDLSENDEAPPAQEGFRLEDVDWNSVAHRYPNLF RAT1_PE3030 NOISO SSWVGRTLRSQTGSVEVVTAEVLRDVSDSSQCAEVPNAGEGFRLEDVDWNSIAHRYPNLF SPETRGS_3814_PE2 NOISO SSWVGRVLRSPTGSVEVVTAETLRDFSDFSEN-EAPTAGEGFRLEDMDWHSIALQYPNLF TUPGBGS_3661_PE2 NOISO SSWVGRVLRSQTGSVEVVTAETLMDSCELSESDQTPVGGEGFRLEDVDWNSIAHRYPNLF TURTR103543_PE3 NOISO SSWVGRTLRSSTGSVEVVTAETLVDPGDLSENDRPPTAGEGFRLENVDWNSVAHRYPNLF MATCH *. : : :. *.* CONSENSUS SSWVGR?LRS?TGSVEVVTAETL????D??????????GEGFRLED?DWNS?A?RYPNLF

AILMEGL194206_1_PE15 NOISO INIESNSDQKHQRPLPPPQA---PLLDEWGSELCRHRMERRLKSVEWSSLPLMGTSS-SG CALJA11_136_PE63 ISOFORMIN TNVELDSQQKQPWPWPQLDTGSPG--------SPGKHSEGHQETVTRGSLPCLGTSS-SG CALJA11_136_PE64 ENSCJAG00000012183 TNVELDSQQKQPWPWPQLDTGSPG--------SPGKHSEGHQETVTRGSLPCLGTSS-SG CANFA18_29_PE29 NOISO TNIECSSDQKHPRPLSPPEA---SLSGEWGSELRRRHMEQRLKSVEWSTLPLVGTSS-SG CAVPO218_PE25 NOISO TSIHSSSEPK--QHQLPSGL------DSPGSDSPRKLVERQHKSLEWSTLPCAGTSS-SG DIPOR17830_PE2 NOISO TNITSSVEQKQIQPRPPSSL------DSLSLDSPDKHPERPGKSLEWSSLPVVRSSS-SE FELCAGS_4243_PE8 NOISO ANIKSNSDQKHPRALPSPPA---PVPGQWGSELHRECVEQHLKSVEWRSLPSVGTSS-SG GORGO11_1_PE32 NOISO TNMEPSSKQKQPRPWPQLDTGSPE--------SSGKHSERHHKTVEWGSPPCLNTSS-SG HORSE12_33_PE10 NOISO TSMESNLDQKHARPPPPPQLSPASTPEEWGSEPRKHGAEHRLKSVEWSALPLVGTSS-SG HS11_PE61 ENSG00000185522 TNMEPSSKQKQPRPWPQLDTGSPE--------SSGKHSERHHKTVEWGSLPCLNTSS-SG LOXAF227_PE2 NOISO TEAVL-LEHKQPRPPPQPPL------NEWDSESRPERTDGHTKSVEWSILPF-GSSS-SG MACMU14_1_PE31 NOISO --------------------------------------TLHPDPKLTRYXPCLNTSS-SG MONDOUN_47_PE11 ENSMODG00000011024 EDISKIKH-RYGRP--LVRRGQPP--------SPSGPSRFRFKSVDWSL-PLPQKSASST MOUSE7_PE3945 NOISO SNLNFYSDQKQSQPP-TSET------YTLDSEGATKHTEKPTKILEWSALPLLDTSS-SE OCHPRGS_3375_PE2 NOISO TDFEPNPEPREP-----P--------------SQGSQPDERHKSVEWSSLPQPSSSS-SR PANTR11_1_PE29 NOISO TNMEPSSKQKQPRPWPQLDTGSPE--------SSGKYSERHHKTVEWGSLPCLNTSS-SG PONPY11_1_PE16 NOISO TSMEPSSKQKQPQPWPQLDTGSSE--------SSRKHSERHHKTVEWGSLPCLNTSS-SG PROCAGS_4986_PE2 NOISO ADVDF-SEYRQ---SLQPPK------DEEDSESRPERVAGHTKSVEWHILPL-RSSS-SG PTEVAGS_2542_PE2 NOISO ATTKSNLDYKHLEPQPPTKQPVAPAPEERGSEPSVHQAERSLKTVEWRPLPLEGTSS-SG RAT1_PE3030 NOISO SSLSFHSDQKLSQPP-ASEV------DACDSECATKHTEKPTKTLEWSALPLVDTSS-SE SPETRGS_3814_PE2 NOISO SDSSTKQK----QPQQSPSL------GKGGSDSSVEHLEKHPKNLEWSSLPCMATSS-SG TUPGBGS_3661_PE2 NOISO TSIHSNSDQKQTRRWPSLPL------DASSSESHRDRVTGRLKSVEWSSLTWVGTSR-SG TURTR103543_PE3 NOISO TNLESSSDQQHPWAPPLPDAG---------NSLYCRQSEHRLKSVEWSSLPLVGTSS-SG MATCH . . .* * CONSENSUS ??????????????????????????????????????????K??EW??LP????SS?S?

AILMEGL194206_1_PE15 NOISO GADSDSSSDQLAERYRVRKVLGHPPCTPGPSSSDLAEA-PSNFSREMQTQPKGLLSLDLR CALJA11_136_PE63 ISOFORMIN GADSDSSSCQQGLPYHLLKASRHSPRGWGASSEKALVQ-ARSFGRGS---------EDLQ CALJA11_136_PE64 ENSCJAG00000012183 GADSDSSSCQQGLPYHLLKASRHSPRGWGASSEKALVQ-ARSFGRGS---------EDLQ CANFA18_29_PE29 NOISO GTDSGSSSGQLAARCRVRKVTGRPPRSPGRKSSEPTEA-HSRI-----FSRESLLSPDLR CAVPO218_PE25 NOISO GADSDSSSCQLVLHPRVQRVIGHPPPAADTASYEQTAVQTKRFSGDS---------EDLQ DIPOR17830_PE2 NOISO GTNADSHHCQPVLHSQGQKVPGYPDLSSE-----QNQTWSESFSKDT---------EGRQ FELCAGS_4243_PE8 NOISO GTDSDPGSGWLAEPHRVQKVTGQPPCAAGRSSEQTPEE-FGRES---RHSEDP----WKP GORGO11_1_PE32 NOISO GADSDSSSCRPGLPSF-VQVIGHPPRDHRASSEQALVQ-AGGYGRDS---------EDLQ HORSE12_33_PE10 NOISO GSISESSTSSQGQA-SKQKVTRPLPQALGHASEQPVAQ-VRSCSR---------DYQA-- HS11_PE61 ENSG00000185522 GADSDSSSCRPGLPSF-VQVIGHPPRDHRASSEQALVQ-AGSYSRDS---------EDLQ LOXAF227_PE2 NOISO ATDSDTRSSQLSIPSRVQKVTGHPPGESSCFSFQPTKGQEKTLSAD---------RQAVL MACMU14_1_PE31 NOISO GVDSDSSSCRPGLPSL-VQVVGHPPRDHRASSKQALVQ-ARSSSRDL---------EDLQ MONDOUN_47_PE11 ENSMODG00000011024 AMAVEGSSAGSNSM----STAGGLETSPSL--VLPVQEEEASSSG--------------- MOUSE7_PE3945 NOISO RTQSDTSSCPIALHSGAKKTTGHPSQGTNLASSEQMQEHTRSFSGYT---------EDLC OCHPRGS_3375_PE2 NOISO GAGSDSSSCQLAKKHRRRGVATRSLGREEPSEGQQM------------------------ PANTR11_1_PE29 NOISO GADSDSSSCRPGLPSF-VQVIGHPPRDHRASSEQALVQ-AGSYSKDS---------EDLQ PONPY11_1_PE16 NOISO GADSDSSICRPGLPSL-VQAIGHTPRDHRASSEQALVQ-AGSHSRDS---------EDLQ PROCAGS_4986_PE2 NOISO ATGSDTTSSQLSVPSRVQKVTGHPPGEFSCSSDQGTKGQEKTLSRS---------TGDLQ PTEVAGS_2542_PE2 NOISO GADSDSSSPRLDLKSRMQKVTGHLPRDQDT-SEQTKPQ-AGSCRRDSQAES-----EDQQ RAT1_PE3030 NOISO SIESDISSSQMVLHSGAKTTTGHPPQGPNLAASEQMQECTRSVNGYT---------EDLH SPETRGS_3814_PE2 NOISO GAGSDSSSCQPVVPSRVQKASGYPPQTEDLASSEQIPTMAWSFGGDS---------EDLL TUPGBGS_3661_PE2 NOISO STDSDSSSCQLALS-SLVQVTGDPPQQPDHASSEQIQT-LKNFSGDSE--------PEGF TURTR103543_PE3 NOISO GADSESSSCLLAARYHVQKVTRDPLQRQ-ATSEQNGAQ--SLCWD------SRATWEDLR MATCH . CONSENSUS ???SD?SS???????????????????????S????????????????????????????

AILMEGL194206_1_PE15 NOISO KAHQDQPGKTVLTRESCAGPEHPHSGRG--WSPTGSCLKIVAVNGRERFVRVLNQSLEET CALJA11_136_PE63 ISOFORMIN KTQSARHRKPVLTPELCTDPDYPGPEHQ--QSPTGSCLKIVAVSVREKLVRILNQSQLET CALJA11_136_PE64 ENSCJAG00000012183 KTQSARHRKPVLTPELCTDPDYPGPEHQ--QSPTGSCLKIVAVSVREKLVRILNQSQLET CANFA18_29_PE29 NOISO KAHQDQPGKTVLTGEPCAGPEHGPPRRR--WSPTGSCLKIIAVSRRDRFVRVLNQSLEET CAVPO218_PE25 NOISO KFGSHLFGQTLL--KPTADLCYLSTGHTESLSRISSSLQIVAVSQREKFVRILNRSLQDA DIPOR17830_PE2 NOISO KPHLGHPSKTVP--KPYADPDYQGSGYQ--LS--QIGLKIVAVNCRERFVRILNQSQEET FELCAGS_4243_PE8 NOISO PPPRDPPGKTVLTGESCADSEHRHPAPP--PCPINSSLKIVTVSRKERFVRVLNQSLEET GORGO11_1_PE32 NOISO KTHSPRHGEPVLSPQPCTDPDHWSAELL--QSPTG--LKIVAVSCRERFVRIFNPSQEST HORSE12_33_PE10 NOISO EPEGGGPGPASQEISPCLCTAPVPSLAR--PSASGCCLKIVAVSRHERFVRILNQSLEET HS11_PE61 ENSG00000185522 KTHSPRHGEPVLSPQPCTDPDHWSPELL--QSPTG--LKIVAVSCREKFVRIFNPSQEST LOXAF227_PE2 NOISO VGAAEEPEQTVLLPKASEDSSHQPHRYR--SRLTGSCLKIVAVSRREKFVRVLNQSLEET MACMU14_1_PE31 NOISO KIHSPRHGGPLLAPQPCTDPDHWSPEHL--QSPTG--LKIVAVSCREKFVRIFNPSQEST MONDOUN_47_PE11 ENSMODG00000011024 RACCPAPSGPLPAGAP----RSGLPR----RKDLNSSLRMVKMDKRGKFIQVLNESLEES MOUSE7_PE3945 NOISO KSHSPSCSKTVL--ESYTDLHHPYTRPQ--LNPFGCCLKIAAVSHREKFIRVINQSQAET OCHPRGS_3375_PE2 NOISO -TSLGEPSR-----SKVAEPDHLHMGSG--LSP--LDLKIVAVSRRQKFVRILNQSREQT PANTR11_1_PE29 NOISO KTHSPRHGEPVLSPQPCTDPDHWSPELL--QSPTG--LKIVAVSCREKFVRIFNPSQEST PONPY11_1_PE16 NOISO KTHSPRHGDPVLSPQPCTDPDHWSPELL--QSPTG--LKIVAVSRREKFVRIFNPSQEST PROCAGS_4986_PE2 NOISO KAHAEEADRTALLSKACKDADHWTHWLP--GRWTDSSLRIVAVSHREKFVRILNLSS-ET PTEVAGS_2542_PE2 NOISO ETDLDRQGK----PRPSADSDSWHPGHR--WSLTGSCLKIVAVSRREKSVRIVNESLEGD RAT1_PE3030 NOISO KSWSPSCSKTVL--ESYTDLQHPYTRPQ--LNPFGCCLKIAAVSHREKFIRIINQSQAET SPETRGS_3814_PE2 NOISO KTHSQPPSK--P--RPCTAPGHRRVSHQ--LSPTGCCLKIVAVSPQEKFVRVLNESREET TUPGBGS_3661_PE2 NOISO QKTSDWPGETALEPEPRADLAH----HC--PDPWPRGLKIVAVSCRGKFVRVFNQSLEDT TURTR103543_PE3 NOISO KTHSDRQGKNGQEPESRADPHPRHYGRC--PSPTGSCLKIMAVSHRRGFVRILNQSLEET MATCH *:: :. : :::.* * CONSENSUS ?????????????????????????????????????LKIVAVS?R??FVR??N?S???T

AILMEGL194206_1_PE15 NOISO ADLGGLTLQQRVRDVPVCVYRFPPGTLLAPRHHVTVWGEGPRPKL--LPSTLGQELVHFH CALJA11_136_PE63 ISOFORMIN ADLGGAVLKQLVRGRPERLYRFPPATLLAPRHHITIWGEGPRNAKKPPCASSGREPQPSH CALJA11_136_PE64 ENSCJAG00000012183 ADLGGAVLKQLVRGRPERLYRFPPATLLAPRHHITIWGEGPRNAKKPPCASSGREPQPSH CANFA18_29_PE29 NOISO VDLSGLTLQQLVQDFPVCMYRFPPGTLLAPRHHVTVWGEGPRSTKKQLPSS-----LGFH CAVPO218_PE25 NOISO ADLGGLVLQQRVHDCPVRMFCFPKGTVLEPQHHLTVWGEGTGGIQQQPPFPSGQDPLQFH DIPOR17830_PE2 NOISO VELGGFLLQQLVQNFPVCMFRFPPGTLLAPRHHITVWGEGTRRTKKQPPIFLGQEPFYFH FELCAGS_4243_PE8 NOISO ADLGGLTLRQLLYGFPVCMYRFPPGTLLAPGHHVTVWGEGPGSTKKQPPSSLGQEPVHFH GORGO11_1_PE32 NOISO ADLSGVVLKQLVRGFPERLYRFPPGTLLAPRHHVTVWGEATRRAKKPLRASSSREPVPLL HORSE12_33_PE10 NOISO ADLGGCMLQQLVRDFPVATYRFPAGMLLAPRHHITVWGEGPPTTKKQPSSFLGGEPVHFH HS11_PE61 ENSG00000185522 ADLSGMVLKQLVRGFPERLYRFPPGTLLAPRHHVTVWGEATRSAKKPLRASSSREPVPLL LOXAF227_PE2 NOISO AYLGGFVLQQFVRGFPVCMYRFPSGTLLEPRHHITVWGEGTSRTKKHPPASLGRESVNFH MACMU14_1_PE31 NOISO ADLSGMVLKQVVRGLPERLYRFPPGTLLAPRHHITVWGEGTRSAKKPPRASSGREPVPLL MONDOUN_47_PE11 ENSMODG00000011024 VDIGGFVLQQLIQHFPGCIYRFPKDTLLAPQHHVTVWGEGVSPTRKRMAKAPQKDLIHFY MOUSE7_PE3945 NOISO IDLGGFVLQQLVRDFPVCMYRFPPGTLLAPQHHITVWGEGTSRTKKQLPVASGQDPFQFQ OCHPRGS_3375_PE2 NOISO ADLAGVTLRQLEHGFPVRLYRFLPGTHLGPRRQLTIWSESGCGTQKRRPLNSGQEPTLFH PANTR11_1_PE29 NOISO ADLSGMVLKQLVRGFPQRLYRFPPGTVLAPRHHVTVWGETTRSAKKPLRASSSREPVPLL PONPY11_1_PE16 NOISO ADLSGMVLKQLVRGFPERLYRFPPGTLLAPRHHVTVWGEATRSAKKPLCASSGRVPVPLL PROCAGS_4986_PE2 NOISO ADLGGFLLQQSVGSFPVSSYRFPLGTCLAPSHHLTVWGETARRTQKRPPVPLGWGPISFH PTEVAGS_2542_PE2 NOISO CDLGGFALQQLQRDFXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX RAT1_PE3030 NOISO VDLGGFVLQQLVRDFPVCMYRFPPGTLLAPQHHITVWGEGTSRTKKQLPVSSGQDPFQFQ SPETRGS_3814_PE2 NOISO VDLDGFLLQQLERGFPVCLYRFPPGTLLAPQHHITVWGQGTSSTKKQPLLSLGQDAGLFH TUPGBGS_3661_PE2 NOISO ADLSDFMLQQLVRDFPVCMYRFPPGTLLAPRHHITVWGEGTSRTRKDPSLSLGREPVHFR TURTR103543_PE3 NOISO ADLGGFVLQQLVRDFPVCMYRFPPSTLLEPRQHITVWGEAPSSTKRQPPFSLGQEPVHFH MATCH : . *:* CONSENSUS ?DL?G??L?Q?????P???YRFP??T?L?P?HH?TVWGE??????K??????????????

AILMEGL194206_1_PE15 NOISO SRRGCVTLLLNPKGEVLSEHQAPPCVSPVSRIFADNTDLSIDRFPLSEAKPAADTCEQRP CALJA11_136_PE63 ISOFORMIN SSPDCVTLLLGPKGEVLSEHRIPHCATPAPRVFADDTDLSIDRFPLPEAGPGADPCEPPG CALJA11_136_PE64 ENSCJAG00000012183 SSPDCVTLLLGPKGEVLSEHRIPHCATPAPRVFADDTDLSIDRFPLPEAGPGADPCEPPG CANFA18_29_PE29 NOISO FNRGCVTLLLNPKGEVLSEYQAPHGVSRGSRIFVDNADLSIDRFPLPEAAPASATLEQMP CAVPO218_PE25 NOISO CGRGCVTLLLDAEGQVLSEYQAPLRVTSGSGIFADNTDWSIDRFPLPEAGAGAHTGKPQC DIPOR17830_PE2 NOISO SSQGCVTLLLNAEGQVLSEHQAPHCATLGSRTFEDNMDWSIDCFPLSEAGLGTDTQEQQR FELCAGS_4243_PE8 NOISO SGRGCVTLLLNPKGEVLSEHRAPHCVTPVSRIFADNTDLSVDRFPLSEDGLGADPGEQSR GORGO11_1_PE32 NOISO SIRGCATLLLSPKGEVLSEHRIPRRETPAPRVFADGTDLSIDRFPLPEAGPGADTRKPPR HORSE12_33_PE10 NOISO SSRSCVTLLLNPKGEVLTEYQPPHCVTPHSRVFTDNTDLSIDCFPLSEAGRGADQGEQPR HS11_PE61 ENSG00000185522 SIRGCATLLLSPKGEVLSEHRIPRRETPAPRVFADGTDLSIDRFPLPEAGPGADTRKPPR LOXAF227_PE2 NOISO SSLGYLTLLLNPKGEVLSEYQAPHCVTPVSRNFSDNSDLSIDRFPLSEAPPGSDTGELQR MACMU14_1_PE31 NOISO SSRGCATLLLSPKGEVLSEHQIPRRETPAPRVFDDGTDLSIDRFPLPEVGPGADTCKPQR MONDOUN_47_PE11 ENSMODG00000011024 THPGCVTLLLNPAGEVMSQYQAPHCVTEASKAFTDYTDMSIDCYPLREAPDTKPQEAVGL MOUSE7_PE3945 NOISO SSRGCVTVLVNPQGQVLSEHQATPCVTLGSKIFTDNTDWSIDCFPLSESEPDVHPGEQQC OCHPRGS_3375_PE2 NOISO VSPGCVTLLLGPKGEVLSEHQAPHCVTATARLCAEDTILSVDGFPLPEAQLGADLPEPRL PANTR11_1_PE29 NOISO SIRGCATLLLSPKGEVLSEHRIPRRETPAPRVFADGTDLSIDRFPLPEAGPGADTRKPPR PONPY11_1_PE16 NOISO SIRGCATLLLSPKGEVLSEHRIPRRETPAPRVFADGTDLSIDRFPLPEAGPGADTRKPPR PROCAGS_4986_PE2 NOISO SSRGCVTRLLNPKGEVLSEYQAPHCVTTVSRDFQDNTDLSVDCFPLAEGPPDPNTCEKRR PTEVAGS_2542_PE2 NOISO XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDNTDLSIDRFLLSEAQSEANAHEQRR RAT1_PE3030 NOISO SSRGCVTMLVNPQGQVLSEHQAVPCVTLGSKIFTDNTDWSIDRFPLSESEPNVDPGDQQY SPETRGS_3814_PE2 NOISO PSLGCLTLLLNPEGQVLSEHQTPHRVTSGSRIFTDNTDWSIDRFPLSKAPPGPDTSGPRS TUPGBGS_3661_PE2 NOISO SSRGCVTLLLNPKGEGCSQHTGPHM--PVSRIFVNND---SDCFPLSEAQPDTDTGQQKR TURTR103543_PE3 NOISO SSRGCVTLLLNPQGEVLSEHQAAHCVTPVCRIFADNTDLSIDRFPLSEARPGADLAERQP MATCH : * : * : CONSENSUS ???GC?TLLL?P?G?VLSE???P???T?????F?D?TD?SID?FPL?E????????????

AILMEGL194206_1_PE15 NOISO GPQPSRAGRVREARARRRRPGPP-ASPGPFPARAALPASGLRISRPPRPPRTRGLFPRLS CALJA11_136_PE63 ISOFORMIN TP---RRGRVRESRVG-RRPRTR------------------------------ALQPPPS CALJA11_136_PE64 ENSCJAG00000012183 TP---RRGRVRESRVG-RRPRTR------------------------------ALQPPPS CANFA18_29_PE29 NOISO GTQHSRAGRAREPRARQRRPRG---TRGPFP--------------------------RQS CAVPO218_PE25 NOISO WPRPPRQGRGREAQSMHRRPG------------------------------TRCLMPLPS DIPOR17830_PE2 NOISO RPLPMCKGRVQESRAGRRKPG------------------------------TWGILPQLS FELCAGS_4243_PE8 NOISO GPQHSRGGRVREAGARRRRPXXX-XXXXXXXXXXXXXXXXXXXXX--------------- GORGO11_1_PE32 NOISO PPRPLRKGRVREPRVSRRRPGTR------------------------------GLLPPVS HORSE12_33_PE10 NOISO RPQPPRKGRVREARAGRRRPGTR------------------------------VPLPRLS HS11_PE61 ENSG00000185522 PPRPLRKGRVREPRVSRRRPGTR------------------------------GLLPPVS LOXAF227_PE2 NOISO GSRSPCKGRARGSRADRGRQRWGRAPHKPTPLQAPPPPCRLRLSGPTCPTRTRVFLPLLS MACMU14_1_PE31 NOISO PPRPLRKGRVREPRVSRRRPRTR------------------------------GLLPPMS MONDOUN_47_PE11 ENSMODG00000011024 RTKS--HRRHLPARKKPKIPGPP---------------------------------PS-- MOUSE7_PE3945 NOISO RPSSPQKGRAKDAGARRKKPGPGVRQ------HRHSSTSGLRASRTLHPTETRDILPLLS OCHPRGS_3375_PE2 NOISO QPPYPRKGRMRQAPGGHGRPPMP----------------------------APMKMPSLS PANTR11_1_PE29 NOISO PPRPLRKGRVREPRVSRRRPGTR------------------------------GLLPPMS PONPY11_1_PE16 NOISO PPRPLRKGRVREPRVSRRRPGTR------------------------------GLLPPMS PROCAGS_4986_PE2 NOISO RSPSRHKGRVRVSRAKRRRPSIH-------------------------------GLLLLS PTEVAGS_2542_PE2 NOISO QPRLPRDGRIREARVGSS--GTP------------------------------ALLPRLG RAT1_PE3030 NOISO RPSSPQKGRAKVAGARHKKPRPGVRQ------QRLSSTGGLRASRPLRPTETRDILPLLS SPETRGS_3814_PE2 NOISO RPRPPGKSRVRETGARRRRPG------------------------------MRDILPLLS TUPGBGS_3661_PE2 NOISO RPRPPCKGRVQEARAKLRKPGTR------------------------------GTLPLLG TURTR103543_PE3 NOISO LPRPPRKGRVQEARAGRRRPGTR------------------------------VQLPRLS MATCH . * . CONSENSUS ?P?????GR??????????P????????????????????????????????????P??S

AILMEGL194206_1_PE15 NOISO TGKIFRSREVPAPSEAAETLA--PELLPAI-P------------------DAGLCL-EDC CALJA11_136_PE63 ISOFORMIN SGKRFHPREGPAQHL-PAIPRERTPEGERG-PP--------DPTPPSPPADAGLGL-EDW CALJA11_136_PE64 ENSCJAG00000012183 SGKRFHPREGPAQHL-PAIPRERTPEGERG-PP--------DPTPPSPPADAGLGL-EDW CANFA18_29_PE29 NOISO ASKLFRPPE------ATGTRA--PERLPAI-PGEDADAEGRRPVLPQGPHDQAWWY-PAC CAVPO218_PE25 NOISO PRKSVHLRQGPAQLEGTKLAM--KSD-----------------PLPTISAEVAQDL-EQG DIPOR17830_PE2 NOISO TRKPCHPGKGPAQREGTKTE---VQQLPPTVPG--------EPPLPLSYTEAGLPL-EKC FELCAGS_4243_PE8 NOISO -XXXXX--X------XXXXXX----XX-XX-X------------XXXXXXXXXXXX-XXX GORGO11_1_PE32 NOISO SGKLFHAREGPARPENPEIPA--PQHLPAI-PG--------DPTLPSPPAEAGLGL-EDC HORSE12_33_PE10 NOISO SGKLFRPRAVPARPERTETHT--PELLPAL-PEGGRP----YPTPSFSHAEAGVGL-EIS HS11_PE61 ENSG00000185522 SGKLFHAREGPARPENPEIPA--PQHLPAI-PG--------DPTLPSPPAEAGLGL-EDC LOXAF227_PE2 NOISO SNKLFHRREGPGRLEGAEAEA--LEPLPAI-------------------PETRPGF-DNQ MACMU14_1_PE31 NOISO SGKLFHAREGPTRPENPEIPV--PQHLPTI-PG--------DPTLPSPPAEAGLGL-ENC MONDOUN_47_PE11 ENSMODG00000011024 ----LEGQAGPYRSRWDAR------PPPPLQPHEGAS--PATSTRPEPHSEAALGRQDSC MOUSE7_PE3945 NOISO SRKLLPSGEVLTQQEGVKAET--SELLPVI-PE--------CP--------SRLCLGEDS OCHPRGS_3375_PE2 NOISO PCDALHSQEVPSQTKCFESPV--PELLPFLLGG---------LTPSSYPTEARLGL-EDC PANTR11_1_PE29 NOISO SGKLFHARERPARPEKPEIPEIPAQHPLRI-PG--------XPTLPSPPAE--------- PONPY11_1_PE16 NOISO SGKLFHEREGPARPETPEIPA--PHHLPAI-PG--------DP--PSPPAEAGLGL-KDC PROCAGS_4986_PE2 NOISO SEKPIHQEVLPRQREGA-TQS--LDPLRTI-PS--------DSTLPCPHTEARPGF-DCS PTEVAGS_2542_PE2 NOISO TSKPFRPPEVPARPESAETTT--RELLPAV-PG--------EHAPSFSHADHRPGF-ADC RAT1_PE3030 NOISO TRKLFPLGEGPAQQEGVKTEI--SELLPVI-PE--------CS--------SRVCLE-DS SPETRGS_3814_PE2 NOISO TCRPFHLPEVPTRPEDSHSET--LELLPPIIPG--------EPP-PLSQTEAGLCP-QDC TUPGBGS_3661_PE2 NOISO TSKPCHPREVPARPERAETKA--PELLPTI-SGDASL------TPAPAETEAESRL-QDC TURTR103543_PE3 NOISO TRKLLRQREVPGRPEGAAETH--PELLPAS-PA--------DPTPSLSRAEAALGL-EDC MATCH CONSENSUS ??K???????P?????????????????????????????????????????????????

AILMEGL194206_1_PE15 NOISO RARTEH--RVRVCRKSVDRSCPMVALSV--------HFRFLPCPPVTTDRKARV- CALJA11_136_PE63 ISOFORMIN RLLKEH--RVRVCRKSVDRSCPMVALSVPSTAQSRYGFRFLNCLPFTMDSCRRA- CALJA11_136_PE64 ENSCJAG00000012183 RLLKEH--RVRVCRKSVDRSCPMVALSVPSTAQSRYGFRFLNCLPFTMDSCRRA- CANFA18_29_PE29 NOISO RHRWPHAPXPQVCRKTVDRSCPMVALSVQSTAESRFGFRFLPCPPVTAGPNVRV- CAVPO218_PE25 NOISO MPGKER--RVSVCRRGVDLGCPIVALSVQSTAESRFGFRFLCCPPITTD------ DIPOR17830_PE2 NOISO LSRRED--KFQVCRKSVDRSCPMVALSVQSTAESKYGFRFLSCPPITTDVC---- FELCAGS_4243_PE8 NOISO XXXXXXXXXXXVCRRSVDPGCPMVALSVQSTAESRYGFRFLPCPPVTADPGAR-- GORGO11_1_PE32 NOISO GLQKEH--RVRV------------------------------------------- HORSE12_33_PE10 NOISO QARKEP--KVRVCRKTVDRSCPMVALSVQSTAESRFGFRFL-------------- HS11_PE61 ENSG00000185522 RLQKEH--RVRVCRKSVDRSCPLVALSVQNTAESRFGFRFLSCLPVTADTCRGA- LOXAF227_PE2 NOISO -AKKKH--TVQVCRKGVDRNCPMVALSVQTTAESRYGFRFLSCPPITVDACGRV- MACMU14_1_PE31 NOISO RLRKEH--QVRVCRKTVYRSCPLVALSVQITAERIFGFRFLSCLPVTADTCRGA- MONDOUN_47_PE11 ENSMODG00000011024 HGAMFL--PPRICRKYVDVECPMVALSVQKTAESRFGLKHLNYPPI--------- MOUSE7_PE3945 NOISO LGRQEY--KVQVCRKSVDLSCPMVALSVQNTAESRYGFRFLCYPPITEELCRRL- OCHPRGS_3375_PE2 NOISO QARKER--QVQVGRRSVDRDCPMVLLSMQNTAESRFGFRFLCCPPITAD------ PANTR11_1_PE29 NOISO ------------------------------------------------------- PONPY11_1_PE16 NOISO LLRKTR--ISGDSRL---XXXXXXXXXXXSTAESRFCSSIISCLPVTADTC---- PROCAGS_4986_PE2 NOISO QPRKEL--RVRVCRKGVDLSCPMVALSVQSTAESRYGFRFLSSPPVTVDACRGAW PTEVAGS_2542_PE2 NOISO QARKEH--RVPVCRKTVDRSCPMVALSVQSTAESRFGFRFLSCPPITVDACLG-- RAT1_PE3030 NOISO LGRQER--KVQVCRKTVDLSCPMVALSVQSTAESRYGFRFLCYPPITEELCRRL- SPETRGS_3814_PE2 NOISO PTRKEC--KVRVCRKNVDRSCPMVTLSVQSTAESRYGFRFLSCPPITVDTC---- TUPGBGS_3661_PE2 NOISO RARKEH--KVRVCRKSVDRSCPMVALSVQSTAESRFGFRFLSCPPLTADACRRV- TURTR103543_PE3 NOISO QARKEH--KVRVGRKSVDRGCPMVALSVQSTAESRFGFRFLSCPPITADSRCGVG MATCH CONSENSUS ???????????V?R??VD??CP?V?LSV??TA?S??GFRFL???P?T????????


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