Alignment of the gene Family HOG000082472 of HOGENOM

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Isoforms are ON
AILMEGL192487_1_2_PE2 NOISO -----MATLEKLMKAFESLKSFQQRSSIQNFL---KG--------RAPSPFLRRDPVPWP ANOCA879_PE7 NOISO ------------------------------------------------------------ BOVIN6_123_PE7 NOISO -----MATLEKLMKAFESLKSFQQQQQQQQQQQQQQQ--------PPPPPQPPQPPQPPP CALJA3_197_PE1 ISOFORMIN -----MATLEKLMKAFESLKSPAGRRRGDRVTQQPQTRRDTRSLLRRDPPPLPPGSRTWV CALJA3_197_PE2 ENSCJAG00000014069 -----MATLEKLMKAFESLKSFQQQQQQQQQ---------------PPPPPPPPPPPPPQ CANFA3_66_PE9 NOISO GREAAMATLEKLMKAFESLKSFQQQQQQQQQQ---P-----------PPPPPPQPPQPLP CAVPO166_3_PE1 NOISO -----MATLEKLMKAFESLKSFQQQQPVRARGAA------------APTVSPRRPRSPSP CHICK4_PE1373 ENSGALG00000015635 -----MATMEKLMKAFESLRSFQQQQVPAAIPEEPTQ--RP-----------A-DPQWKL CHICK4_PE1374 ISOFORMIN -----MATMEKLMKAFESLRSFQQQQVPAAIPEEPTQ--RP-----------A-DPQWKL CIOIN5Q_4_PE92 ENSCING00000012200 ------------------------------------------------------------ CIOSAREFTIG_48_4_PE28 ENSCSAVG00000011198 -----NIAMEKLVKSVNALKFFHGGL---------------------------------- CIOSAREFTIG_48_4_PE30 ISOFORMIN -----NIAMEKLVKSVNALKFFHGGL---------------------------------- CIOSAREFTIG_48_4_PE31 ISOFORMIN ------------------------------------------------------------ DANRE1_43_PE16 NOISO -----MATMEKLMKAFESLKSFQQQQGPLSAEELVQKQ---------------------- DIPORGS_6403_PE1 NOISO ------------------------------------------------------------ ECHTEGS_8301_PE1 NOISO -----MATLEKLMKAFESLKSFQQQQQQQ------------------PPPPPPQPPQPPP FELCAGS_590_PE5 NOISO ------------------------------------------------------------ FUGRU62_1_PE15 ENSTRUG00000005174 -----MATMEKLMKAFESLKSFQQQQGPPTAEEIVQRQ---------------------- FUGRU62_1_PE16 ISOFORMIN -----MATMEKLMKAFESLKSFQQQQGPPTAEEIVQRQ---------------------- GASACGROUPIX_12_PE29 ENSGACG00000018347 -----MATMEKLMKAFESLKSFQQQQGPPTAEELVQRQ---------------------- GASACGROUPIX_12_PE30 ISOFORMIN -----MATMEKLMKAFESLKSFQQQQGPPTAEELVQRQ---------------------- GORGO4_4_PE8 ENSGGOG00000016385 ------------------------------------------------------------ GORGO4_4_PE9 ISOFORMIN ------------------------------------------------------------ HORSE3_121_PE1 NOISO ------------------------------------------------------------ HS4_PE336 ENSG00000197386 -----MATLEKLMKAFESLKSFQQQQQQQQQQQQQQQQQ-----QQQQPPPPPPPPPPPQ LOXAF18_3_PE1 ENSLAFG00000013021 -----MATLEKLMKAFESLKSFQQQQQQQQQQ---Q------------QPPPPQPPQLP- LOXAF18_3_PE2 ISOFORMIN ------------------------------------------------------------ MACMU1_1_PE10 NOISO -----MATLEKLMKAFESLKSPAGRRHEPPRPRSDRVTQQPRANEGHPPPP-AARPSPTS MICMUGS_1602_PE2 NOISO -------------------------------------------------PLLPLPPLPPH MONDO5_236_PE5 ENSMODG00000003615 ------------------------------------------------------------ MONDO5_236_PE6 ISOFORMIN ------------------------------------------------------------ MOUSE5_PE653 ENSMUSG00000029104 -----MATLEKLMKAFESLKSFQQQQQQQPPPQA-PP--------PPPPPPPPQPP---- MOUSE5_PE654 ISOFORMIN -----MATLEKLMKAFESLKSFQQQQQQQPPPQA-PP--------PPPPPPPPQPP---- MYOLUGS_2052_PE1 NOISO -----MATLEKLMKAFESLKSFQQQQQQQQQQP--------------PPPPPPQXXXXXX ORYLA1_40_PE1 NOISO -----MATMEKLMKAFESLKSFQQQQGPPTAEELVQKQ---------------------- OTOGAGS_4539_PE1 NOISO ------------------------------------------------------------ PANTR4_4_PE11 NOISO -----MATLEKLMKAFESLKSFQQQQQQQQQ-------Q-----QQQQQPPPPPPPLPPQ PIG8_2_PE5 NOISO -----MATLEKLMKAFESLKSFQQQQQQQQQQQQQQQ--------QQPPPPPPQPPQPPP POEGU4_64_PE9 NOISO ------------------------------------------------------------ PONPY4_4_PE8 NOISO -----MATLEKLMKAFESLKSFQQQQQQ----------Q-----QQQPPPPPPPPPPPPQ PROCAGS_7171_PE1 NOISO ------------------------------------------------------------ PTEVAGS_485_PE5 NOISO -----MATLEKLMKAFESLKSFQQQQQPSPP-------------------QPPQPPPPQA RABITUN0098_2_PE1 NOISO ---------------------------------PPPASQGPRRL-GRPPP-ASQGPRRLG RAT14_PE728 ENSRNOG00000011073 -----MATLEKLMKAFESLKSFQQQQQQQQPPPQ-AP--------PPPPPPPPQPP---- RAT14_PE729 ISOFORMIN ------------MKAFESLKSFQQQQQQQQPPPQ-AP--------PPPPPPPPQPP---- RAT14_PE730 ISOFORMIN ------------MKAFESLKSFQQQQQQQQPPPQ-AP--------PPPPPPPPQPP---- SORARGS_2621_PE1 NOISO -----MATLEKLMKAFESLKSFQQQQQQP-------------------PPPPSQLPQPPP SPETRGS_688_PE4 NOISO -----------------------------------------------PPP---QP----- TARSYGS_7946_PE1 NOISO -----MATLEKLMKAFESLKSFQQQQQQP-------------------PPPPPQLPQTPT TETNG18_PE387 ENSTNIG00000012050 ------------MKAFESLKSFQQQQGPPTAEEIVQRQ----------------QPTE-- TUPGBGS_5468_PE1 NOISO ------------------------------------------------------------ TURTRGS_3325_PE1 NOISO ---------------FESKSQ---QQQQQQQQ---QQ--------LHQQPP--------- MATCH CONSENSUS ????????????????????????????????????????????????????????????

AILMEGL192487_1_2_PE2 NOISO CPGPPAGACAA-PQAASLLSV-RE-PPPLPLVPESEPAIWDHRLYKKKKELSATKKDRVN ANOCA879_PE7 NOISO ---------------------------------------AEEPPQRPKKELSTTKKDRVN BOVIN6_123_PE7 NOISO -------------------QA-QPPPQPPPPPPPLGPAAAEEPLHRPKKELSATKKDRVH CALJA3_197_PE1 ISOFORMIN FPGP-PAGRGR-ASWEPVLK--SPRRSPSPSPPFPVLTVKLKGLHLPKKELSATKKDRVN CALJA3_197_PE2 ENSCJAG00000014069 LPQP-PP------QAQPLLP--QPQPPPPPPPPPPGPAAAEEPLHRPKKELSATKKDRVN CANFA3_66_PE9 NOISO -------------QAQPPLP--QP-PPPPPPPPPPGPAVAEEPLHRPKKELSATKKDRVN CAVPO166_3_PE1 NOISO ALGSPA----L-PS----PPR-PVFSAPPPGRGASSPGVASLSRAQRKKELSATKKDRVN CHICK4_PE1373 ENSGALG00000015635 GSWPPAPTVQFDTDAKSLIPRLNRKTGNAVVPLGTLISSLPELFHFRKKELLTTKKDRVN CHICK4_PE1374 ISOFORMIN GSWPPAPTVQFDTDAKEN-------------------------THERKKELLTTKKDRVN CIOIN5Q_4_PE92 ENSCING00000012200 -----------------------------------------------QKDALQSPNERQS CIOSAREFTIG_48_4_PE28 ENSCSAVG00000011198 -----------------------------------------SSEDKTQKDSLQSPTERQN CIOSAREFTIG_48_4_PE30 ISOFORMIN -----------------------------------------SSEDKTQKDSLQSPTERQN CIOSAREFTIG_48_4_PE31 ISOFORMIN --------------------------------------------------------ERQN DANRE1_43_PE16 NOISO -----------------------------------------------KKDLATTKKDRVT DIPORGS_6403_PE1 NOISO -----------------------------------------------KKELAATKKDRVN ECHTEGS_8301_PE1 NOISO QA-----------------------QPPPPPPPPPGPSVAEEPPHRXXXXXXXXXXXXXX FELCAGS_590_PE5 NOISO -----------------------------------------------KKELSATKKDRVN FUGRU62_1_PE15 ENSTRUG00000005174 -----------------------------------------------KKEQATTKKDRVS FUGRU62_1_PE16 ISOFORMIN -----------------------------------------------KKEQATTKKDRVS GASACGROUPIX_12_PE29 ENSGACG00000018347 -----------------------------------------------KKEQATTKKDRVT GASACGROUPIX_12_PE30 ISOFORMIN -----------------------------------------------KKEQATTKKDRVT GORGO4_4_PE8 ENSGGOG00000016385 -----------------------------------------------KKELSATKKDRVN GORGO4_4_PE9 ISOFORMIN -----------------------------------------------KKELSATKKDRVN HORSE3_121_PE1 NOISO -----------------------------------------------KKELSATKKDRVN HS4_PE336 ENSG00000197386 LPQP-PP------QAQPLLP--QPQPPPPPPPPPPGPAVAEEPLHRPKKELSATKKDRVN LOXAF18_3_PE1 ENSLAFG00000013021 ------------------PQT-QPPPPPPPPPPPPGPAVAEEPLHRPKKELLNTKKDRVN LOXAF18_3_PE2 ISOFORMIN -------------------------------PPCSGPQ---PASQRKKKELLNTKKDRVN MACMU1_1_PE10 NOISO APVP---------HLGLVLP--REHPERSPYPSPPFPVWSKQKLYRTKKELSATKKDRVN MICMUGS_1602_PE2 NOISO -----LS----------QAQQWPHLRLPPPQPPPLGPAVAEEQLPRPKKELSATKKDRVN MONDO5_236_PE5 ENSMODG00000003615 ----------------------------------PGPSGVEEPAHRPKKELSTTKKDRVN MONDO5_236_PE6 ISOFORMIN -----------------------------------------------KKELSTTKKDRVN MOUSE5_PE653 ENSMUSG00000029104 --------------------Q-PPPQGQPPPPPPPLPGPAEEPLHRPKKELSATKKDRVN MOUSE5_PE654 ISOFORMIN --------------------Q-PPPQGQPPPPPPPLPGPAEEPLHRPKKELSATKKDRVN MYOLUGS_2052_PE1 NOISO XXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX ORYLA1_40_PE1 NOISO -----------------------------------------------KKEQATTKKDRVT OTOGAGS_4539_PE1 NOISO -----------------------------------------------KKELSATKKDRVN PANTR4_4_PE11 NOISO LPQP-PP------QAQPLLP--QPQPPPPPPPPPPGPAVAEEPLHRPKKELSATKKDRVN PIG8_2_PE5 NOISO QTQP--------------PPQ-PPPPPPPPPPPPPGPAVAEEPLHRPKKELSATKKDRVN POEGU4_64_PE9 NOISO ------------------------------------------------------------ PONPY4_4_PE8 NOISO LPQP-PP------QAQPLLP--QQQPPPPPPPPPPGPAVAEEPLHRPKKELSFSWKDRVN PROCAGS_7171_PE1 NOISO -----------------------------------------------KKELLNTKKDRVN PTEVAGS_485_PE5 NOISO Q------------------PP-PPQPQPPPPPPPPGPAVAEEPLHRPKKELSATKKDRVN RABITUN0098_2_PE1 NOISO RPPPPSQGPRR-LAI---------------SPALPGAQALGPSSTALKKELSATKKDRVN RAT14_PE728 ENSRNOG00000011073 --------------------Q-PPPQGQPPP-PPPLPGPAEEPLHRPKKELSATKKDRVN RAT14_PE729 ISOFORMIN --------------------Q-PPPQGQPPP-PPPLPGPAEEPLHRPKKELSATKKDRVN RAT14_PE730 ISOFORMIN --------------------Q-PPPQGQPPP-PPPLPGPAEEPLHRPKKELSATKKDRVN SORARGS_2621_PE1 NOISO QAQPP-----------------PPQPQPPPPPPPQGPAGADEPLHRPKKELLATKKDRVN SPETRGS_688_PE4 NOISO --------------------THAELQPPPPPPPPAPLCVAEEPLPRPKKELSATKKDRVN TARSYGS_7946_PE1 NOISO QAQPP---------------PPQPQPPPPPPPPPPGPTVAEEPLHRPKKELSATKKDRVN TETNG18_PE387 ENSTNIG00000012050 ----------------------------HAIEIELENAPNPEESLFRKKEQATTKKDRVT TUPGBGS_5468_PE1 NOISO ------------------------------------------------------------ TURTRGS_3325_PE1 NOISO -------------QAQPPLPQ-SPPPPPPPPPPPPGPAVAEEPLHRPKKELSATKKDRVN MATCH CONSENSUS ???????????????????????????????????????????????KKE???TKKDRV?

AILMEGL192487_1_2_PE2 NOISO HCLTICENIVAQSL-RNSPEFQKLLGIAMELFLLCSDDAESDVRMVADECLNRVIKALM- ANOCA879_PE7 NOISO HCLTICENIVAQSL-RNSPEFQKLLGIAMELFLLCSDDVESDVRMVADECLNKVIKALM- BOVIN6_123_PE7 NOISO HCLTICENIVAQSL-RNSPEFQKLLGIAMELFLLCSDDAESDVRMVADECLNKVIKALM- CALJA3_197_PE1 ISOFORMIN HCLTICENIVAQSV-RNSPEFQKLLGIAMELFLLCSDDAESDVRMVADECLNKVIKALM- CALJA3_197_PE2 ENSCJAG00000014069 HCLTICENIVAQSV-RNSPEFQKLLGIAMELFLLCSDDAESDVRMVADECLNKVIKALM- CANFA3_66_PE9 NOISO HCLTICENIVAQSL-RNSPEFQKLLGIAMELFLLCSDDAESDVRMVADECLNRVIKALM- CAVPO166_3_PE1 NOISO HCLTICENIVAQSL-RNSPEFQKLLGIAMELFLLCGDDAESDVRMVADECLNKVIKALM- CHICK4_PE1373 ENSGALG00000015635 HCLTICENIVAQSL-RNSPEFQKLLGIAMELFLLCSEDVESDVRMVADECLNKVIKALM- CHICK4_PE1374 ISOFORMIN HCLTICENIVAQSL-RNSPEFQKLLGIAMELFLLCSEDVESDVRMVADECLNKVIKALM- CIOIN5Q_4_PE92 ENSCING00000012200 HCNIVLESIISPSI-RSLADYPGLLAVSVETLLQSCADDNADVRLNANECLNRLIKGLY- CIOSAREFTIG_48_4_PE28 ENSCSAVG00000011198 HCNIITDSIISQSI-RSLVDFPGLLAVSVETLLQSCADENADVRLNSNECLNRVIKGLY- CIOSAREFTIG_48_4_PE30 ISOFORMIN HCNIITDSIISQSI-RSLVDFPGLLAVSVETLLQSCADENADVRLNSNECLNRVIKGLY- CIOSAREFTIG_48_4_PE31 ISOFORMIN HCNIITDSIISQSI-RSLVDFPGLLAVSVETLLQSCADENADVRLNSNECLNRVIKGLY- DANRE1_43_PE16 NOISO HCLTICENIVAQSL-RTSPEFQKLLGIAMEMFLLCSDDKESDVRMVADECLNKIIKALM- DIPORGS_6403_PE1 NOISO HCLTICENIVAQSL-RNSPEFQKLLGIAMELFLLCSDDAESDVRMVADECLNKVIKALM- ECHTEGS_8301_PE1 NOISO X-XXXXXXXXXXXXXXNSPEFQKLLGIAVELFLLCSDDAESDVRMVADECLNKVIKALM- FELCAGS_590_PE5 NOISO HCLTICENIVAQSL-RNSPEFQKLLGIAMELFLLCSDDAESDVRMVADECLNRVIKALM- FUGRU62_1_PE15 ENSTRUG00000005174 HCLTICENIVAQSL-RTSPEFQKLLGIAMEMFLLCSDDSESDVRMVADECLNRIIKALM- FUGRU62_1_PE16 ISOFORMIN HCLTICENIVAQSL-RTSPEFQKLLGIAMEMFLLCSDDSESDVRMVADECLNRIIKALM- GASACGROUPIX_12_PE29 ENSGACG00000018347 HCLTICENIVAQSL-RTSPEFQKLLGIAMEMFLLCSDDSESDVRMVADECLNKIIKALM- GASACGROUPIX_12_PE30 ISOFORMIN HCLTICENIVAQSL-RTSPEFQKLLGIAMEMFLLCSDDSESDVRMVADECLNKIIKALM- GORGO4_4_PE8 ENSGGOG00000016385 HCLTICENIVAQSV-RNSPEFQKLLGIAMELFLLCSDDAESDVRMVADECLNKVIKALM- GORGO4_4_PE9 ISOFORMIN HCLTICENIVAQSV-RNSPEFQKLLGIAMELFLLCSDDAESDVRMVADECLNKVIKALM- HORSE3_121_PE1 NOISO HCLTICENIVAQSL-RNSPEFQKLLGIAMELFLLCSDDAESDVRMVADECLNKVIKALM- HS4_PE336 ENSG00000197386 HCLTICENIVAQSV-RNSPEFQKLLGIAMELFLLCSDDAESDVRMVADECLNKVIKALM- LOXAF18_3_PE1 ENSLAFG00000013021 HCLTICENIVAQSL-RNSPEFQKLLGIAMELFLLCSDDAESDVRMVADECLNKVIKALM- LOXAF18_3_PE2 ISOFORMIN HCLTICENIVAQSLSRNSPEFQKLLGIAMELFLLCSDDAESDVRMVADECLNKVIKALM- MACMU1_1_PE10 NOISO HCLTICENIVAQSV-RNSPEFQKLLGIAMELFLLCSDDAESDVRMVADECLNKVIKKTFV MICMUGS_1602_PE2 NOISO HCLTICENIVAQSL-RNSPEFQKLLGIAMELFLLCSDDAESDVRMVADECLNKVIKALM- MONDO5_236_PE5 ENSMODG00000003615 HCLTICENIVA----QNSPEFQKLLGIAMELFLLCSDDAESDVRMVADECLNKVIKALM- MONDO5_236_PE6 ISOFORMIN HCLTICENIVAHSL-QNSPEFQKLLGIAMELFLLCSDDAESDVRMVADECLNKVIKALM- MOUSE5_PE653 ENSMUSG00000029104 HCLTICENIVAQSL-RNSPEFQKLLGIAMELFLLCSDDAESDVRMVADECLNKVIKALM- MOUSE5_PE654 ISOFORMIN HCLTICENIVAQSL-RNSPEFQKLLGIAMELFLLCSDDAESDVRMVADECLNKVIKALM- MYOLUGS_2052_PE1 NOISO XXXXXXXXXXXXXXXXNSPEFQKLLGIAMELFLLCSDDAESDVRMVADECLNKVIKALM- ORYLA1_40_PE1 NOISO HCLTICENIIAQSL-RTSPEFQKLLGIAMEMFLLCSDDSESDVRMVADECLNKIIKALM- OTOGAGS_4539_PE1 NOISO HCLTICENIVAQSL-RNSPEFQKLLGIAMELFLLCSDDAESDVRMVADECLNKVIKALM- PANTR4_4_PE11 NOISO HCLTICENIVAQSV-RNSPEFQKLLGIAMELFLLCSDDAESDVRMVADECLNKVIKALM- PIG8_2_PE5 NOISO HCLTICENIVAQSL-RNSPEFQKLLGIAMELFLLCSDDAESDVRMVADECLNKVIKALM- POEGU4_64_PE9 NOISO ------------------------------------------------------------ PONPY4_4_PE8 NOISO HCLTICENIVAXXL-RNSPEFQKLLGIAMELFLLCSDDAESDVRMVADECLNKVIKALM- PROCAGS_7171_PE1 NOISO HCLTICENIVAQSL-RNSPEFQKLLGIAMELFLLCSDDAESDVRMVADECLNRVIKALM- PTEVAGS_485_PE5 NOISO HCLTICENIVAQSL-RNSPEFQKLLGIAMELFLLCSDDAESDVRMVADECLNKVIKALM- RABITUN0098_2_PE1 NOISO HCLTICENIVAQSLSRNSPEFQKLLGIAMELFLLCSDDAESDVRMVADECLNKVIKALM- RAT14_PE728 ENSRNOG00000011073 HCLTICENIVAQSL-RNSPEFQKLLGIAMELFLLCSDDAESDVRMVADECLNKVIKALM- RAT14_PE729 ISOFORMIN HCLTICENIVAQSL-RNSPEFQKLLGIAMELFLLCSDDAESDVRMVADECLNKVIKALM- RAT14_PE730 ISOFORMIN HCLTICENIVAQSL-RNSPEFQKLLGIAMELFLLCSDDAESDVRMVADECLNKVIKALM- SORARGS_2621_PE1 NOISO HCLTICENIVAQSL-RNSPEFQKLLGIAMELFLLCSDDAESDVRMVADECLNKVIKALM- SPETRGS_688_PE4 NOISO HCLTICENIVAQSL-RNSPEFQKLLGIAMELFLLCSDDAESDVRMVADECLNKVIKALM- TARSYGS_7946_PE1 NOISO HCLTICENIVAQSL-RNSPEFQKLLGIAMELFLLCSDDAESDVRMVADECLNKVIKXXXX TETNG18_PE387 ENSTNIG00000012050 HCLTICENIVAQSL-RMSPEFQKLLGIAMETFLLCSDD-----RMVADECLNKIIKALM- TUPGBGS_5468_PE1 NOISO ----------------NSPEFQKLLGIAMELFLLCSDDAESDVRMVADECLNKVIKALM- TURTRGS_3325_PE1 NOISO HCLTICENIVAQSL-RNSPEFQKLLGIAMELFLLCSDDAESDVRMVADECLNKVIKALM- MATCH CONSENSUS HCLTICENIVAQS??R?SPEFQKLLGIAME?FLLCSDD?ESDVRMVADECLN?VIKALM?

AILMEGL192487_1_2_PE2 NOISO --DSSLPRLQLELYKEIKKNGAPRSLRAALWRFAELAHLVRPQKC--RPYLVNLLPCLTR ANOCA879_PE7 NOISO --DSNLPRLQLELYKEIKKNGASRSLRAALWRFAELAHLVRPQKC--RPYFVNLLPCLTR BOVIN6_123_PE7 NOISO --DSNLPRLQLELYKEIKKNGAPRSLRAALWRFAELAHLVRPQKC--RPYLVNLLPCLTR CALJA3_197_PE1 ISOFORMIN --DSNLPRLQLELYKEIKKNGAPRSLRAALWRFAELAHLVRPQKCSHRPYLVNLLPCLTR CALJA3_197_PE2 ENSCJAG00000014069 --DSNLPRLQLELYKEIKKNGAPRSLRAALWRFAELAHLVRPQKC--RPYLVNLLPCLTR CANFA3_66_PE9 NOISO --DSNLPRLQLELYKEIKKNGAPRSLRAALWRFAELAHLVRPQKC--RPYLVNLLPCLTR CAVPO166_3_PE1 NOISO --DSNLPRLQLELYKEIKKNGAPRSLRAALWRFAELAHLVRPQKC--RPYLVNLLPCLTR CHICK4_PE1373 ENSGALG00000015635 --DSNLPRLQLELYKEIKKNGASRSLRAALWRFAELAHLVRPQKC--RPYLVNLLPCLTR CHICK4_PE1374 ISOFORMIN --DSNLPRLQLELYKEIKKNGASRSLRAALWRFAELAHLVRPQKC--RPYLVNLLPCLTR CIOIN5Q_4_PE92 ENSCING00000012200 --EISNSKILVELYKEIKKNGHPRSLRAALDRFSRLSHNIRSNKC--RPYILNLLPCLCR CIOSAREFTIG_48_4_PE28 ENSCSAVG00000011198 --DVSVSKILVELYKEIKKNGHARSLRAALKRFSYLSPNIRSNKC--RPYILNLLPCLCR CIOSAREFTIG_48_4_PE30 ISOFORMIN --DVSVSKILVELYKEIKKNGHARSLRAALKRFSYLSPNIRSNKC--RPYILNLLPCLCR CIOSAREFTIG_48_4_PE31 ISOFORMIN --DVSVSKILVELYKEIKKNGHARSLRAALKRFSYLSPNIRSNKC--RPYILNLLPCLCR DANRE1_43_PE16 NOISO --DSNLPRLQLELYKEIKKNAASRSLRAALWRFAELAHLVRPQKC--RPYLVNLLPCLTR DIPORGS_6403_PE1 NOISO --DSNLPRLQLELYKEIKKNGAPRSLRAALWRFAELAHLVRPQKC--RPYLVNLLPCLTR ECHTEGS_8301_PE1 NOISO --DSNLPRLQLELYKEIKKXXXXXXXXXXXXXXX--XXXXXXXXXXXXPYLVNLLPCLTR FELCAGS_590_PE5 NOISO --DSNLPRLQLELYKEIKKNGAPRSLRAALWRFAELAHLVRPQKC--RPYLVNLLPCLTR FUGRU62_1_PE15 ENSTRUG00000005174 --DSNLPRLQLELYKEIKKNGASRSLRAALWRFAELAHLIRPQKC--RPYLVNLLPCLTR FUGRU62_1_PE16 ISOFORMIN --DSNLPRLQLELYKEIKKNGASRSLRAALWRFAELAHLIRPQKC--RPYLVNLLPCLTR GASACGROUPIX_12_PE29 ENSGACG00000018347 --DSNLPRLQLELYKEIKKNGASRSLRAALWRFAELAHLIRPQKC--RPYLVNLLPCLSR GASACGROUPIX_12_PE30 ISOFORMIN --DSNLPRLQLELYKEIKKNGASRSLRAALWRFAELAHLIRPQKC--RPYLVNLLPCLSR GORGO4_4_PE8 ENSGGOG00000016385 --DSNLPRLQLELYKEIKKNGAPRSLRAALWRFAELAHLVRPQKCRHRPYLVNLLPCLTR GORGO4_4_PE9 ISOFORMIN --DSNLPRLQLELYKEIKKNGAPRSLRAALWRFAELAHLVRPQKCR--PYLVNLLPCLTR HORSE3_121_PE1 NOISO --DSNLPRLQLELYKEIKKNGAPRSLRAALWRFAELAHLVRPQKC--RPYLVNLLPCLTR HS4_PE336 ENSG00000197386 --DSNLPRLQLELYKEIKKNGAPRSLRAALWRFAELAHLVRPQKCR--PYLVNLLPCLTR LOXAF18_3_PE1 ENSLAFG00000013021 --DSNLPRLQLELYKEIKKNGAPRSLRAALWRFAELAHLVRPQKC--RPYLVNLLPCLTR LOXAF18_3_PE2 ISOFORMIN --DSNLPRLQLELYKEIKKNGAPRSLRAALWRFAELAHLVRPQKC--RPYLVNLLPCLTR MACMU1_1_PE10 NOISO KLNQGLIRLLVLFKKISQNNGAPRSLRAALWRFAELAHLVRPQKCRHRPYLVNLLPCLSR MICMUGS_1602_PE2 NOISO --DSNLPRLQLELYKEIKKNGAPRSLRAALWRFAELAHLVRPQKC--RPYLVNLLPCLTR MONDO5_236_PE5 ENSMODG00000003615 --ESNLPRLQLELYKEIKKNGASRSLRAALWRFAELAHLVRPQKC--RPYLVNLLPCLTR MONDO5_236_PE6 ISOFORMIN --ESNLPRLQLELYKEIKKNGASRSLRAALWRFAELAHLVRPQKC--RPYLVNLLPCLTR MOUSE5_PE653 ENSMUSG00000029104 --DSNLPRLQLELYKEIKKNGAPRSLRAALWRFAELAHLVRPQKC--RPYLVNLLPCLTR MOUSE5_PE654 ISOFORMIN --DSNLPRLQLELYKEIKKNGAPRSLRAALWRFAELAHLVRPQKC--RPYLVNLLPCLTR MYOLUGS_2052_PE1 NOISO --DSNLPRLQLELYKEIKKNGAPRSLRAALWRFAELAHLVRPQKC--RPYLVNLLPCLTR ORYLA1_40_PE1 NOISO --DSNLPRLQLELYKEIKKNGASRSLRAALWRFAELAHLIRPQKC--RPYLVNLLPCLTR OTOGAGS_4539_PE1 NOISO --DSNLPRLQLELYKEIKKNGAPRNLRAALWSFAELAHLVSPQKC--RPYLVNLLPCLTR PANTR4_4_PE11 NOISO --DSNLPRLQLELYKEIKKNGAPRSLRAALWRFAELAHLVRPQKCR--PYLVNLLPCLTR PIG8_2_PE5 NOISO --DSNLPRLQLELYKEIKKNGAPRSLRAALWRFAELAHLVRPQKC--RPYLVNLLPCLTR POEGU4_64_PE9 NOISO ------------------------------------------------------------ PONPY4_4_PE8 NOISO --DSNLPRLQLELYKEIKKNGAPRSLRAALWRFAELAHLVRPQKCR--PYLVNLLPCLTR PROCAGS_7171_PE1 NOISO --DSSLPRLQLELYKEIKKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX PTEVAGS_485_PE5 NOISO --DSNLPRLQLELYKEIKKNGAPRSLRAALWRFAELAHLVRPQKC--RPYLVNLLPCLTR RABITUN0098_2_PE1 NOISO --DSNLPRLQLELYKEIKKNGAPRSLRAALWRFAELAHLVRPQKC--RPYLVNLLPCLTR RAT14_PE728 ENSRNOG00000011073 --DSNLPRLQLELYKEIKKNGAPRSLRAALWRFAELAHLVRPQKC--RPYLVNLLPCLTR RAT14_PE729 ISOFORMIN --DSNLPRLQLELYKEIKKNGAPRSLRAALWRFAELAHLVRPQKC--RPYLVNLLPCLTR RAT14_PE730 ISOFORMIN --DSNLPRLQLELYKEIKKNGAPRSLRAALWRFAELAHLVRPQKC--RPYLVNLLPCLTR SORARGS_2621_PE1 NOISO --DSNLPRLQLELYKEIKKNGASRSLRAALWRFAELAHLVRPQKCXXXXXXXXXXXXXXX SPETRGS_688_PE4 NOISO --DSNLPRLQLELYKEIKKNGASRSLRAALWRFAELAHLVRPQKC--RPYLVNLLPCLT- TARSYGS_7946_PE1 NOISO XXXXXXXXXXXXXXXXXXX-----XXXXXXXXXXXXXXXXXXXXXXXXPYLVNLLPCLTP TETNG18_PE387 ENSTNIG00000012050 --DSNLPRLQLELYKEIKKNGASRSLRAALWRFAELAHLIRPQKC--RPYLVNLLPCLTR TUPGBGS_5468_PE1 NOISO --DSNLPRLQLELYKEIKKNGAPRSLRAALWRFAELAHLVRPQKC--RPYLVNLLPCLTR TURTRGS_3325_PE1 NOISO --DSNLPRLQLELYKEIKKNGAPRSLRAALWRFAELAHLVRPQKC--RPYLVNLLPCLTR MATCH CONSENSUS ??DSNLPRLQLELYKEIKKNGA?RSLRAALWRFAELAHL?RPQKC??RPYLVNLLPCLTR

AILMEGL192487_1_2_PE2 NOISO ISKRPEESVQETLAAAVPKIMASFGNFANDNEIKVLLKAFIANLKSSSPTIRRTAAGSAV ANOCA879_PE7 NOISO VSNRSEESVQETLAAAIPKIMAAFGNFANDNEIKILLKAFVANLKSTSPTIRRTAAASVV BOVIN6_123_PE7 NOISO TSKRPEESVQETLAAAIPKIMASFGNFANDNEIKVLLKAFIANLKSSSPTVRRTAAGSVV CALJA3_197_PE1 ISOFORMIN TSKRPEESVQETLAAAVPKIMASFGNFANDNEIKVLLKAFIANLKSSSPTIRRTAAGSAV CALJA3_197_PE2 ENSCJAG00000014069 TSKRPEESVQETLAAAVPKIMASFGNFANDNEIKVLLKAFIANLKSSSPTIRRTAAGSAV CANFA3_66_PE9 NOISO ISKRPEESVQETLAAAVPKIMASFGNFANDNEIKVLLKAFIANLKSSSPTIRRTAAGSAV CAVPO166_3_PE1 NOISO TSKRPEESVQETLAAAVPKIMASFGNFANDNEIKVLLKAFIANLKSSSPTVRRTAAGSAV CHICK4_PE1373 ENSGALG00000015635 ISKRPEESVQETLAAAIPKIMAAFGNFANDNEIKVLLKAFIANLKSSSPTIRRTAAGSAV CHICK4_PE1374 ISOFORMIN ISKRPEESVQETLAAAIPKIMAAFGNFANDNEIKVLLKAFIANLKSSSPTIRRTAAGSAV CIOIN5Q_4_PE92 ENSCING00000012200 ISQREEDGVQETLGLSLVKIFKILGPFASESEIQGLLASFLKNLSHKSATMRRTACVCLH CIOSAREFTIG_48_4_PE28 ENSCSAVG00000011198 ISQREEDAVQEVLSSSLAKIFIVLGAFASESEIQGLLASFLKNLSHKSPTVRRTACICLH CIOSAREFTIG_48_4_PE30 ISOFORMIN ISQREEDAVQEVLSSSLAKIFIVLGAFASESEIQGLLASFLKNLSHKSPTVRRTACICLH CIOSAREFTIG_48_4_PE31 ISOFORMIN ISQREEDAVQEVLSSSLAKIFIVLGAFASESEIQGLLASFLKNLSHKSPTVRRTACICLH DANRE1_43_PE16 NOISO ITKRQEETVQETLSSSIPKIMAALGHFANDGEIKMLLKAFVANLKSSSPTIRRTAASSAV DIPORGS_6403_PE1 NOISO TSKRPEESVQETLAAAIPKIMASFGNFANDNEIKVLLKAFIANLKSNSPTVRRTAAGSAV ECHTEGS_8301_PE1 NOISO ISKRPEESVQETLAAAVPKIMASFGNFANDNEIKALLKAFIANLKSGSPTIRRTAAGAAV FELCAGS_590_PE5 NOISO ISKRPEESVQETLAAAVPKIMASFGNFANDNEIKVLLKAFIANLKSSSPTIRRTAAGSAV FUGRU62_1_PE15 ENSTRUG00000005174 ITKRQEETIQETLAAAMPKIMAALGHFANDGEIKMLLKSFVANLKSSSPTIRRTAASSAV FUGRU62_1_PE16 ISOFORMIN ITKRQEETIQETLAAAMPKIMAALGHFANDGEIKMLLKSFVANLKSSSPTIRRTAASSAV GASACGROUPIX_12_PE29 ENSGACG00000018347 ITKRQEETVQETLAAAMPKIMGALGHFANDGEIKVLLKSFVANLKSSSPTIRRTAASSAV GASACGROUPIX_12_PE30 ISOFORMIN ITKRQEETVQETLAAAMPKIMGALGHFANDGEIKVLLKSFVANLKSSSPTIRRTAASSAV GORGO4_4_PE8 ENSGGOG00000016385 TSKRPEESVQETLAAAVPKIMASFGNFANDNEIKVLLKAFIANLKSSSPTIRRTAAGSAV GORGO4_4_PE9 ISOFORMIN TSKRPEESVQETLAAAVPKIMASFGNFANDNEIKVLLKAFIANLKSSSPTIRRTAAGSAV HORSE3_121_PE1 NOISO TSKRPEESVQETLATAIPKIMASFGNFANDNEIKVLLKAFIANLKSSSPTIRRTAAGSAV HS4_PE336 ENSG00000197386 TSKRPEESVQETLAAAVPKIMASFGNFANDNEIKVLLKAFIANLKSSSPTIRRTAAGSAV LOXAF18_3_PE1 ENSLAFG00000013021 ISKRPEESVQETLAAAIPKIMASFGNFANDNEIKVLLKAFMANLKSSSPTIRRTAAGSAV LOXAF18_3_PE2 ISOFORMIN ISKRPEESVQETLAAAIPKIMASFGNFANDNEIKVLLKAFMANLKSSSPTIRRTAAGSAV MACMU1_1_PE10 NOISO TSKRPEESVQETLAAAVPKIMASFGNFANDNEIKVLLKAFIANLKSSSPTIRRTAAGSAV MICMUGS_1602_PE2 NOISO TSKRPEESVQETLAAAVPKIMASFGNFANDNEIKVLLKAFIVNLKSSSPTIRRTAAGSAV MONDO5_236_PE5 ENSMODG00000003615 ISKRTEESVQETLAAAIPKIMASFGNFANDNEIKVLLKAFIANLKSSSPTIRRTAAGSAV MONDO5_236_PE6 ISOFORMIN ISKRTEESVQETLAAAIPKIMASFGNFANDNEIKVLLKAFIANLKSSSPTIRRTAAGSAV MOUSE5_PE653 ENSMUSG00000029104 TSKRPEESVQETLAAAVPKIMASFGNFANDNEIKVLLKAFIANLKSSSPTVRRTAAGSAV MOUSE5_PE654 ISOFORMIN TSKRPEESVQETLAAAVPKIMASFGNFANDNEIKVLLKAFIANLKSSSPTVRRTAAGSAV MYOLUGS_2052_PE1 NOISO TSKRPEESVQETLAAAIPKIMASLGNFANDNEIKVLLKAFITNLKSSSPTTRRTAAACVV ORYLA1_40_PE1 NOISO ITKRQEETVQETLAAATPKIMAALGNFANDGEVKLLLKSFVANLKSSSPTIRRTAASSAV OTOGAGS_4539_PE1 NOISO TSKRPEESVQETLAAAVPKIMASFGNFANDNEIKVLLKAFIANLKSSSPTIRRTAAGSAV PANTR4_4_PE11 NOISO TSKRPEESVQETLAAAVPKIMASFGNFANDNEIKVLLKAFIANLKSSSPTIRRTAAGSAV PIG8_2_PE5 NOISO TSKRPEESVQETLAAAVPKIMASFGNFANDNEIKVLLKAFVANLKSGSPTVRRTAAGAAV POEGU4_64_PE9 NOISO ------------------------------------------------------------ PONPY4_4_PE8 NOISO TSKRPEESVQETLAAAVPKIMASFGNFANDNEIKVLLKAFIANLKSSSPTIRRTAAGSAV PROCAGS_7171_PE1 NOISO XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXX PTEVAGS_485_PE5 NOISO TSKRPEESVQETLAAAIPKIMASFGNFANDNEIKVLLKAFVANLKSSSPTVRRTAAGCAV RABITUN0098_2_PE1 NOISO TSKRPEESVQETLAAAVPKIMASFGNFANDNEIKVLLKAFIANLKSSSPAVRRTAASAAV RAT14_PE728 ENSRNOG00000011073 TSKRPEESVQETLAAAVPKIMASFGNFANDNEIKVLLKAFIANLKSSSPTVRRTAAGSAV RAT14_PE729 ISOFORMIN TSKRPEESVQETLAAAVPKIMASFGNFANDNEIKVLLKAFIANLKSSSPTVRRTAAGSAV RAT14_PE730 ISOFORMIN TSKRPEESVQETLAAAVPKIMASFGNFANDNEIKVLLKAFIANLKSSSPTVRRTAAGSAV SORARGS_2621_PE1 NOISO XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXX SPETRGS_688_PE4 NOISO TSKRPEVSVQETLAAAVPKIMASFXXXXXXXXXXLLLKAFIANLKSSSPTVRRTAAGSAV TARSYGS_7946_PE1 NOISO TSKKTEESVQETLAAAVPKIMAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX TETNG18_PE387 ENSTNIG00000012050 ITKRQEETIQETLAAAMPKIMAALGHFANDGEIKVLLKSFVANLKSSSPTIRRTAASSAV TUPGBGS_5468_PE1 NOISO TSKRPEESVQETLAAAVPKIMASFGNFANDNEIKVLLKAFIANLKSSSPTIRRTAAGSAV TURTRGS_3325_PE1 NOISO TSKRPEESVQETLAAAVPKIMASFGNFANDNEIKVLLKAFIANLKCSSPTVRRTAAGSAV MATCH CONSENSUS ?SKR?EE?VQETLAAA?PKIMA??G?FAND?EIK?LLK?F?ANLKS?SPT?RRTAA???V

AILMEGL192487_1_2_PE2 NOISO SICQHSRRTQYFYNWLLNVLLGLLVPVEGEHSTLLILGVLLTLRYLVPLLQQQVKDTSLK ANOCA879_PE7 NOISO SICQHSRRTQYFYTWLLNVLLGLLFPMEDEYPSVLILGVLLTLRYLIPLLQQQVKDTSLK BOVIN6_123_PE7 NOISO SICQHSRRTQYFYSWLLSVLLGLLVPVEGEHPTLLILGVLLALRYLVPLLQQQVKDTSLK CALJA3_197_PE1 ISOFORMIN SICQHSRRTHYFYSWLLNVLLGLLVPVEDEHSTLLILGVLLTLRYLVPLLQQQVKDTSLK CALJA3_197_PE2 ENSCJAG00000014069 SICQHSRRTHYFYSWLLNVLLGLLVPVEDEHSTLLILGVLLTLRYLVPLLQQQVKDTSLK CANFA3_66_PE9 NOISO SICQHSRRTQYFYSWLLNVLLGLLVPVEGEHSTLLILGVLLTLRYLVPLLQQQVKDTSLK CAVPO166_3_PE1 NOISO SICQHSRRTQYFYSWLLNVLLGLLVPVEEEHPTLLILGVLLTLRYLVPLLQQQVKDTSLK CHICK4_PE1373 ENSGALG00000015635 SICQHSRRTQYFYAWLLNVLLGLLVPVEDDHPTLLILGVLLTLRYLIPLLQQQVKDTSLK CHICK4_PE1374 ISOFORMIN SICQHSRRTQYFYAWLLNVLLGLLVPVEDDHPTLLILGVLLTLRYLIPLLQQQVKDTSLK CIOIN5Q_4_PE92 ENSCING00000012200 SVILNCRKQNLVIGPLMNSILDILLQRNTDR--NTVLGCLQALRILSPLFETCVPGKISE CIOSAREFTIG_48_4_PE28 ENSCSAVG00000011198 SILTNSRKKNVVIGPLVHSIIDILLQRSTDR--NTVLGCLQALRILNPLFKITVQGKITD CIOSAREFTIG_48_4_PE30 ISOFORMIN SILTNSRKKNVVIGPLVHSIIDILLQRSTDR--NTVLGCLQALRILNPLFKITVQGKITD CIOSAREFTIG_48_4_PE31 ISOFORMIN SILTNSRKKNVVIGPLVHSIIDILLQRSTDR--NTVLGCLQALRILNPLFKITVQGKITD DANRE1_43_PE16 NOISO SVCQHSRRTHYFYTWLLNVLLGLVVPVDEEHSSHLILGVLLTLRYLMPLIQQQTPSTSLK DIPORGS_6403_PE1 NOISO SICQHSRRTQYFYSWLLNVLLGLLVPVEEEHSTLLILGVLLTLRYLVPLLQQQVKDTSLK ECHTEGS_8301_PE1 NOISO SVCQHSRRAQHFYSWLLNVLLGLLLPMEDEHPTLLTLGVLLTLRYLVPLLQQQVKDTSLK FELCAGS_590_PE5 NOISO TICQHSRRTQYFYSWLLNVLLGLLVPVEDEHSTLLILGVLLTLRYLVPLLQQQVKDTSLK FUGRU62_1_PE15 ENSTRUG00000005174 SVCQHSRRTSYFYTWLLNVLLGLLVPVDEEHHSHLILGVLLTLRYLMPLLQQQVNTISLK FUGRU62_1_PE16 ISOFORMIN SVCQHSRRTSYFYTWLLNVLLGLLVPVDEEHHSHLILGVLLTLRYLMPLLQQQVNTISLK GASACGROUPIX_12_PE29 ENSGACG00000018347 SVCQHSRRTSYFYTWLLNVLLGLLVPVDEEHPSHLILGVLLTLRYLMPLLQQQVNTTSLK GASACGROUPIX_12_PE30 ISOFORMIN SVCQHSRRTSYFYTWLLNVLLGLLVPVDEEHPSHLILGVLLTLRYLMPLLQQQVNTTSLK GORGO4_4_PE8 ENSGGOG00000016385 SICQHSRRTQYFYSWLLNVLLGLLVPVEDEHSTLLILGVLLTLRYLVPLLQQQVKDTSLK GORGO4_4_PE9 ISOFORMIN SICQHSRRTQYFYSWLLNVLLGLLVPVEDEHSTLLILGVLLTLRYLVPLLQQQVKDTSLK HORSE3_121_PE1 NOISO SICQHSRRTQYFYTWLLNVLLGLLVPVEDEHSTLLILGVLLTLRYLVPLLQQQVKDTSLK HS4_PE336 ENSG00000197386 SICQHSRRTQYFYSWLLNVLLGLLVPVEDEHSTLLILGVLLTLRYLVPLLQQQVKDTSLK LOXAF18_3_PE1 ENSLAFG00000013021 SVCQHCRRTQYFYSWLLNVLLGLLVPVEDEHPTLLILGVLLTLRYLVPLLQQQVKDMSLK LOXAF18_3_PE2 ISOFORMIN SVCQHCRRTQYFYSWLLNVLLGLLVPVEDEHPTLLILGVLLTLRYLVPLLQQQVKDMSLK MACMU1_1_PE10 NOISO SICQHSRRTQYFYSWLLNVLLGLLVPVEEEHSTLLILGVLLTLRYLVPLLQQQVKDTSLK MICMUGS_1602_PE2 NOISO SICQHSRRTQYFYSWLLNVLLGLLVPIEDEHSTLLILGVLLTLRYLVPLLQQQVKDTSLK MONDO5_236_PE5 ENSMODG00000003615 SICQHSRRTQYFYTWLLNVLLGLLVPVEEEHSTLFILGVLLTLRYLIPLLQQQVKDMSLK MONDO5_236_PE6 ISOFORMIN SICQHSRRTQYFYTWLLNVLLGLLVPVEEEHSTLFILGVLLTLRYLIPLLQQQVKDMSLK MOUSE5_PE653 ENSMUSG00000029104 SICQHSRRTQYFYNWLLNVLLGLLVPMEEEHSTLLILGVLLTLRCLVPLLQQQVKDTSLK MOUSE5_PE654 ISOFORMIN SICQHSRRTQYFYNWLLNVLLGLLVPMEEEHSTLLILGVLLTLRCLVPLLQQQVKDTSLK MYOLUGS_2052_PE1 NOISO SICQHSRRTQYFYSWLLSVLLGLLVPVEGEHPSLLVLGALLTLRYLVPLLQQQVQDTSLK ORYLA1_40_PE1 NOISO SVCQHSRRTSYFYTWLLNVLLGLLVPVDEEHPSHLILGTLLTLRYMMPLLQQQVNTTSLK OTOGAGS_4539_PE1 NOISO SICQHSRRTQYFYSWLLNVLLGLLVPVEDEHSTLLILGVLLTLRYLVPLLQQQVKDTSLK PANTR4_4_PE11 NOISO SICQHSRRTQYFYSWLLNVLLGLLIPVEDEHSTLLILGVLLTLRYLVPLLQQQVKDTSLK PIG8_2_PE5 NOISO SVCQHSRRTRYFYSWLLSVLLGLLVPVEEEHGTLLILGVLLTLRYLVPLLQQQVKDTSLK POEGU4_64_PE9 NOISO ------------------------------------------------------------ PONPY4_4_PE8 NOISO SICQHSRRTQYFYSWLLNVLLGLLVPVEDEHSTLLILGVLLTLRYLVPLLQQQVKDTSLK PROCAGS_7171_PE1 NOISO XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXX PTEVAGS_485_PE5 NOISO SICQHSRRTQYFYSWLLNALSGLLVPVEDEHPTLLILGVLLTLRYLVPLLQQQVKDTSLK RABITUN0098_2_PE1 NOISO SVCQHSRRTQYFYSWLLNVLLGLLVPVEEEHSTPLVLGVLLTLRYLVPLLQQQVKDTSLK RAT14_PE728 ENSRNOG00000011073 SICQHSRRTQYFYNWLLNVLLGLLVPMEEDHPTLLILGVLLTLRCLVPLLQQQVKDTSLK RAT14_PE729 ISOFORMIN SICQHSRRTQYFYNWLLNVLLGLLVPMEEDHPTLLILGVLLTLRCLVPLLQQQVKDTSLK RAT14_PE730 ISOFORMIN SICQHSRRTQYFYNWLLNVLLGLLVPMEEDHPTLLILGVLLTLRCLVPLLQQQVKDTSLK SORARGS_2621_PE1 NOISO -XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXX SPETRGS_688_PE4 NOISO SICQHSRRTQYFYSWLLNVLLGLLVPVEEEHPTLLILGVLLTLRYLVPLLQQQVKDTSLK TARSYGS_7946_PE1 NOISO XXXXXXXXXXXXXXXXXXXXXXLLVPVEDEHSTLLILGVLLTLRYLVPLLQQQVKDTSLK TETNG18_PE387 ENSTNIG00000012050 SVCQHSRRTSYFYTWLLNVLLGLLVPVDEEHHSHLILGVLLTLRYLMPLLQQQVNTISLK TUPGBGS_5468_PE1 NOISO SICQHSRRTQYFYSWLLNVLLGLLVPVEEEHSTLLILGVLLTLRYLVPLLQQQVKDTSLK TURTRGS_3325_PE1 NOISO SICQHSRRTQYFYSWLLSVLLGLLVPVEEERSALLILGVLLTLRYLVPLLQQQVKDTSLK MATCH CONSENSUS S?CQHSRRT?YFY?WLL?VLLGLLVP????H???LILGVLLTLR?L?PLLQQQV???SLK

AILMEGL192487_1_2_PE2 NOISO GSFGVTRKELEVSPSTEQLIQVYELTLHYTQHQDHNAVTGALELLQQLFRTPPPELLQAL ANOCA879_PE7 NOISO GSFGVTQKETEISPSLNQLVQVYELSLHYTQHRDHNVVTGSLELLQQLLRTPPPNLLLAL BOVIN6_123_PE7 NOISO GSFGVTRKEMEVSPSTEQLVQVYELTLHYTQHQDHNVVTGALELLQQLLRTPPPELLRVL CALJA3_197_PE1 ISOFORMIN GSFGVTRKEMEVSPSAEQLIQVYELTLHHTQHQDHNVVTGALELLQQLFRTPPPELLQAL CALJA3_197_PE2 ENSCJAG00000014069 GSFGVTRKEMEVSPSAEQLIQVYELTLHHTQHQDHNVVTGALELLQQLFRTPPPELLQAL CANFA3_66_PE9 NOISO GSFGVTRKELEVSPSTEQLIQVYELTLHYTQHQDHNAVTGALELLQQLFRTPPPELLQAL CAVPO166_3_PE1 NOISO GSFGVTQKEMEVSPSAEQLVQVYELTLHHTQHQDHNVVTGALELLQQLFRTPPPVLLQAL CHICK4_PE1373 ENSGALG00000015635 GSFGVTRKETEISPSPEQLIQVYELTLHYTQHQDHNVVTGALELLQQLFRTPPPELLHAL CHICK4_PE1374 ISOFORMIN GSFGVTRKETEISPSPEQLIQVYELTLHYTQHQDHNVVTGALELLQQLFRTPPPELLHAL CIOIN5Q_4_PE92 ENSCING00000012200 QHIL-NEHRDLVLK-------VFDACVFYLDNTDHTIVTAALELLEHLLNEFSSELASVL CIOSAREFTIG_48_4_PE28 ENSCSAVG00000011198 NQVL-KQHRDLILKV------AFDACIFYLDNTDHTIVTATLELLDNLLSGFPSELSAVL CIOSAREFTIG_48_4_PE30 ISOFORMIN NQVL-KQHRDLILKVVLRLTKAFDACIFYLDNTDHTIVTATLELLDNLLSGFPSELSAVL CIOSAREFTIG_48_4_PE31 ISOFORMIN NQVL-KQHRDLILKVVLRLTKAFDACIFYLDNTDHTIVTATLELLDNLLSGFPSELSAVL DANRE1_43_PE16 NOISO GSFGLVRKEADVTPAPEQLIQVYELTLHYTQHWDHNVVTASLELLQQMFRTPPPELLNVL DIPORGS_6403_PE1 NOISO GSFGVTRKEMEVSPSAEQLVQVYELTLHHTQHQDHNVVTGALELLQQLFRTPPPELLQAL ECHTEGS_8301_PE1 NOISO GSFGVTRKEAEVSPTTEQLIQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XX FELCAGS_590_PE5 NOISO GSFGVTRKEMEVCPSTEQLIQVYELTLHYTQHQDHNAVTGALELLQQLFRTPPPELLQAL FUGRU62_1_PE15 ENSTRUG00000005174 GSFGVMQKEADVQPAPEQLLQVYELTLHYTQHWDHNVVTAALELLQQTLRTPPPELLHVL FUGRU62_1_PE16 ISOFORMIN GSFGVMQKEADVQPAPEQLLQVYELTLHYTQHWDHNVVTAALELLQQTLRTPPPELLHVL GASACGROUPIX_12_PE29 ENSGACG00000018347 GSFGVMRKEADVQPTPEQLLQVYELTLHYTQHWDHNVVTAALELLQQMFRTPPPELLHML GASACGROUPIX_12_PE30 ISOFORMIN GSFGVMRKEADVQPTPEQLLQVYELTLHYTQHWDHNVVTAALELLQQMFRTPPPELLHML GORGO4_4_PE8 ENSGGOG00000016385 GSFGVTRKEMEVSPSAEQLVQVYELTLHHTQHQDHNVVTGALELLQQLFRTPPPELLQTL GORGO4_4_PE9 ISOFORMIN GSFGVTRKEMEVSPSAEQLVQVYELTLHHTQHQDHNVVTGALELLQQLFRTPPPELLQTL HORSE3_121_PE1 NOISO GSFGVTRKEMEVSPSTEQLVQVYELTLRYTQHQDHNVVTGALELLQQLFRTPPPELLQAL HS4_PE336 ENSG00000197386 GSFGVTRKEMEVSPSAEQLVQVYELTLHHTQHQDHNVVTGALELLQQLFRTPPPELLQTL LOXAF18_3_PE1 ENSLAFG00000013021 GSFGVTRKEMEVSPSTEQLVQVYELTLHYTQHPDHNVVTGALELLQQIFRTPPPELLQAL LOXAF18_3_PE2 ISOFORMIN GSFGVTRKEMEVSPSTEQLVQVYELTLHYTQHPDHNVVTGALELLQQIFRTPPPELLQAL MACMU1_1_PE10 NOISO GSFGVTRKEMEVSPSAEQLVQVYELTLHHTQHQDHNVVTGALELLQQLFRTPPPELLQAL MICMUGS_1602_PE2 NOISO GSFGVTRKEMEVSPSAEQLVQVYELTLHHTQHQDHNVVTGALELLQQLFRTPPPELLQGL MONDO5_236_PE5 ENSMODG00000003615 GSFGVTRKETEISPSTDQLIQVYELTLHYTQHQDHNVVTGALELLQQLFKTPPVELLQAL MONDO5_236_PE6 ISOFORMIN GSFGVTRKETEISPSTDQLIQVYELTLHYTQHQDHNVVTGALELLQQLFKTPPVELLQAL MOUSE5_PE653 ENSMUSG00000029104 GSFGVTRKEMEVSPSTEQLVQVYELTLHHTQHQDHNVVTGALELLQQLFRTPPPELLQAL MOUSE5_PE654 ISOFORMIN GSFGVTRKEMEVSPSTEQLVQVYELTLHHTQHQDHNVVTGALELLQQLFRTPPPELLQAL MYOLUGS_2052_PE1 NOISO GSFGVTRKEMEVSPSTEQLVQVYELTLHYAQHPDHNVVTGALELLQQLLRTPPPELLRAL ORYLA1_40_PE1 NOISO GSFGVMRKEADVQPTPEQMLQVYELTLHYTQHWDHNVVTAALELLQQTFRTPPPELLHLL OTOGAGS_4539_PE1 NOISO GSFGVTQKEMEVSPSAEQLVQVYELTLHHTQHQDHNVVTGALELLQQLFRTPPPELLQAL PANTR4_4_PE11 NOISO GSFGVTRKEMEVSPSAEQLVQVYELTLHHTQHQDHNVVTGALELLQQLFRTPPPELLQTL PIG8_2_PE5 NOISO GSFGVTRKEMEVSPSTEQLVQVYELTLHYTQHQDHNVVTGALELLQQLLRTPPPELLQAL POEGU4_64_PE9 NOISO ------------------------------------------------------------ PONPY4_4_PE8 NOISO GSFGVTRKEMEVSPSAEQLVQVYELTLHHTQHQDHNVVTGALELLQQLFRTPPPELLQTL PROCAGS_7171_PE1 NOISO XXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX PTEVAGS_485_PE5 NOISO GSFGVTRKEMEVSPSTEQLVQVYELTLRYTQHQDHNVVTGALELLQQLFRTPPPELLQAL RABITUN0098_2_PE1 NOISO GSFGVTRKEMEVCPSAEQLVQVYELTLHHTQHRDHNVVTGALELLQQLFRTPPPELLHAL RAT14_PE728 ENSRNOG00000011073 GSFGVTRKEMEVSPSAEQLVQVYELTLHHTQHQDHNVVTGALELLQQLFRTPPPELLQAL RAT14_PE729 ISOFORMIN GSFGVTRKEMEVSPSAEQLVQVYELTLHHTQHQDHNVVTGALELLQQLFRTPPPELLQAL RAT14_PE730 ISOFORMIN GSFGVTRKEMEVSPSAEQLVQVYELTLHHTQHQDHNVVTGALELLQQLFRTPPPELLQAL SORARGS_2621_PE1 NOISO XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX SPETRGS_688_PE4 NOISO GSFGVTRKEMEVSPSAEQLVQVYELTLHHTQHQDHNVVTGALELLQQLFRTPPPELLQAL TARSYGS_7946_PE1 NOISO GSFGVTRKEMEVSPSTEQLVQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXX TETNG18_PE387 ENSTNIG00000012050 GSFGVMQKEADVQPSPEQLLQVYELTLHYTQHWDHNVVTAALELLQQTLRTPPPELLHML TUPGBGS_5468_PE1 NOISO GSFGVTRKEMEVSPSAEQLVQVYELTLHHTQHQDHNVVTGALELLQQLLRTPPPELLQAL TURTRGS_3325_PE1 NOISO GSFGVTRKEMEVSPSTEQLVQVYELTLHYTQHQDHNVVTGALELLQQLLRTPPPELLRVL MATCH CONSENSUS GSFGV??KE????P??EQL?QVYELTL??TQH?DHN?VT?ALELLQQ???TPP?ELL??L

AILMEGL192487_1_2_PE2 NOISO STPGG-GPLAAAHRQPGCR---SRSGSIVELL-AGGGSSCSPVL-SRKQKGKVLFGEAA- ANOCA879_PE7 NOISO TTAGGITQACVSKDVVASR---NRSDSIVELI-AGGGSSCSPVF-SRKQKAKIFLGGEE- BOVIN6_123_PE7 NOISO TTAGGVRQLAASKDEPGGR---SRSGSIVELI-AGGGSSCSPVL-SRKQKGKVLFGEAA- CALJA3_197_PE1 ISOFORMIN TTVGGIRQLTEAKDESGGR---SRSGSIVELI-AGGGSSCSPVL-SRKQKGKVLLGEEE- CALJA3_197_PE2 ENSCJAG00000014069 TTVGGIRQLTEAKDESGGR---SRSGSIVELI-GNSGSSCSPVL-SRKQKGKVLLGEEE- CANFA3_66_PE9 NOISO STPGG-GLLNATQQQPGCR---SRSSSIVELL-AGGGSSCSPVL-SRKQKGKVLFGEAA- CAVPO166_3_PE1 NOISO TTPGGLAQLSAAQDEARGR---GRSESIVELLVTAGGGSCSPGL-SRKQKGKVLLGEEE- CHICK4_PE1373 ENSGALG00000015635 TSLGGIAQVSVSKDESAIR---SRSGSIVELI-AGGGSSCSPVL-ARKHKGKILLGEEE- CHICK4_PE1374 ISOFORMIN TSLGGIAQVSVSKDESAIR---SRSGSIVELI-AGGGSSCSPVL-ARKHKGKILLGEEE- CIOIN5Q_4_PE92 ENSCING00000012200 IVCGKLKPTSFTPSTVLPDEVETKATSVR-------KILCS------------------- CIOSAREFTIG_48_4_PE28 ENSCSAVG00000011198 TKVGALNETSFTPSATKMDIVQDKSVT-------------------LKKLLQVLLKHKL- CIOSAREFTIG_48_4_PE30 ISOFORMIN TKVGALNETSFTPSATKMDIVQDKSVTRD-------EGWCVIWVIIVKKLLQVLLKHKL- CIOSAREFTIG_48_4_PE31 ISOFORMIN TKVGALNETSFTP----------------------------------------------- DANRE1_43_PE16 NOISO ITRGKITHTSVFREEVESR---ARSGSILELI-AG-GSTCSPLL-LRKQKGKLLSGEEE- DIPORGS_6403_PE1 NOISO TMPGGLGQLAAAQEEAQGR---DRSGSIVELL-AGGGSSCSPIL-SRKQKGKILLGEEE- ECHTEGS_8301_PE1 NOISO XXXXXXXXXXXXXXXXXXX---XXXXXXXXXXXXXXGSSCSPVL-PRKQKXXXXXXXXXX FELCAGS_590_PE5 NOISO TAPGG-GQRSGVQYGPGGR---SRSGSIAELL-AGGGSSCSPVL-SRKQKGKVLFGDAA- FUGRU62_1_PE15 ENSTRUG00000005174 ITAGSIQHASVFRQDIESR---ARSGSILELI-AGGGSTCSPLL-HRKHRGKMLSGEED- FUGRU62_1_PE16 ISOFORMIN ITAGSIQHASVFRQDIESR---ARSGSILELI-AGGGSTCSPLL-HRKHRGKMLSGEED- GASACGROUPIX_12_PE29 ENSGACG00000018347 ITAGSILHGTVFRQDAESR---ARSSSIRELI-AGGGSSCSPLV-LRKPRGKMLSGEED- GASACGROUPIX_12_PE30 ISOFORMIN ITAGSILHGTVFRQDAESR---ARSSSIRELI-AGGGSSCSPLV-LRKPRGKMLSGEED- GORGO4_4_PE8 ENSGGOG00000016385 TAVGGIGQLTAAKEESGGR---SRSGSIVELI-AGGGSSCSPVL-SRKQKGGYCSGRQCE GORGO4_4_PE9 ISOFORMIN TAVGGIGQLTAAKEESGGR---SRSGSIVELI-AGGGSSCSPVL-SRKQKA--------- HORSE3_121_PE1 NOISO TTAGGLGRLAAAKDEPSCR---SRSGSIVELI-AGGGSSCSPVL-SRKQKGKVLLGEAA- HS4_PE336 ENSG00000197386 TAVGGIGQLTAAKEESGGR---SRSGSIVELI-AGGGSSCSPVL-SRKQKGKVLLGEEE- LOXAF18_3_PE1 ENSLAFG00000013021 TTAGGLGRLSMARDEPSCR---SRSGSIVELI-AGGGSSCSPVL-SRKQKGKVLLGEEE- LOXAF18_3_PE2 ISOFORMIN TTAGGLGRLSMARDEPSCR---SRSGSIVELI-AGGGSSCSPVL-SRKQKGKVLLGEEE- MACMU1_1_PE10 NOISO TTVGGIGQLTAAKEESGGR---SRSGSIVELI-AGGGSSCSPVL-SRKQKGKVLLGEEE- MICMUGS_1602_PE2 NOISO TTPGGLGQLTVAKDESSGR---SRSGSIVELISXXXXXXX-XXX-XXXXXXRVLLSEEA- MONDO5_236_PE5 ENSMODG00000003615 TTAGGFGQVNVTKEE-FSR---SRSGSIVELI-AGGGSSCSPVL-SRKQKGKVLLGEEE- MONDO5_236_PE6 ISOFORMIN TTAGGFGQVNVTKEE-FSR---SRSGSIVELI-AGGGSSCSPVL-SRKQKGKVLLGEEE- MOUSE5_PE653 ENSMUSG00000029104 TTPGGLGQLTLVQEEARGR---GRSGSIVELL-AGGGSSCSPVL-SRKQKGKVLLGEEE- MOUSE5_PE654 ISOFORMIN TTPGGLGQLTLVQEEARGR---GRSGSIVELL-AGGGSSCSPVL-SRKQKGKVLLGEEE- MYOLUGS_2052_PE1 NOISO TTPGGLAQLSAPRQEPGSR---SRSGSIVELI-GDWGSSCSPVL-SRKQKGKVLLGEAA- ORYLA1_40_PE1 NOISO ITAGSIPHATVFRQDNESR---ARSGSILELI-AGGGSSCSPLL-LRKQRGKVLSGEED- OTOGAGS_4539_PE1 NOISO TTPGGLGQLTVAKEESSGR---SRSGSIVELISNXXXXXXXXXX-XXXXXXXXXXXXXXX PANTR4_4_PE11 NOISO TAVGGIGQLTAAKEESGGR---SRSGSIVELI-AGGGSSCSPVL-SRKQKGKVLLGEEE- PIG8_2_PE5 NOISO TSPGGIAQLTANNDEPRCR---SRSGSIVELI-AGGGSSCSPVL-SRKQKGKVLLGDAA- POEGU4_64_PE9 NOISO ------------------------------------------------------------ PONPY4_4_PE8 NOISO TTVGGIGQLTAAKEESGGR---SRSGSIVELI-AGGGSSCSPVL-SRKQKGKVLLGEEE- PROCAGS_7171_PE1 NOISO XXXXXXXXXXXXXXXXXXX---XXXXXXXXXXXXGEGSSCSPVF-SRKQKGKVLLGEEA- PTEVAGS_485_PE5 NOISO TTAGGLAQLPATRDQPGGR---GRSGSIVELI-AGGGSSCSPVL-SRKQKGKVLFGEAA- RABITUN0098_2_PE1 NOISO TTPGGLGQLPAAEEESAGQ---SRSGSIVDLL-AGGGSSCSPVP-SRKHKGKVLLGEEE- RAT14_PE728 ENSRNOG00000011073 TTPGGLGQLTLVREEAGGR---GRSGSIVELL-AGGGSSCSPVL-SRKQKGKVLLGEEE- RAT14_PE729 ISOFORMIN TTPGGLGQLTLVREEAGGR---GRSGSIVELL-AGGGSSCSPVL-SRKQKGKVLLGEEE- RAT14_PE730 ISOFORMIN TTPGGLGQLTLVREEAGGR---GRSGSIVELL-AGGGSSCSPVL-SRKQKGKVLLGEEE- SORARGS_2621_PE1 NOISO XXXXXXXXXXXXXXXXXXX---XXXXXXXXXXXXXWGSSCSPVL-PRKQKGMVLLGEAA- SPETRGS_688_PE4 NOISO TTPGGLGQLAAAQEDAQGR---SRSRSIVELL-GSWSSSCSPIL-SRKQKGRVLMGEEE- TARSYGS_7946_PE1 NOISO XXXXXXXXXXXXXXXXXXX---XXXXXXXXXXXXGGGSSCSPVL-SRKQKGKVLLGEEE- TETNG18_PE387 ENSTNIG00000012050 ITAGSIQHASVFRQDAESR---ARSGSILELI-AGGGATCSPLL-HRKHRGKMLSGEED- TUPGBGS_5468_PE1 NOISO TMAGGIGQLTVAKDE-SSR---SRSGSIVELIGXX-XXXXXXXX-XXXXXXKVLLGEEE- TURTRGS_3325_PE1 NOISO TTAGGIGQLTAAKDEPGCR---SRSGSIVELI-AGGGSSCSPVL-SRKQKGKVLFGEAA- MATCH CONSENSUS ???G??????????????R????RS?SI?EL?????GS?CSP????RK?????L?G????

AILMEGL192487_1_2_PE2 NOISO -ALEDDSESRSEGSSPAFAASVKGEIGGELAA-SSGVSTPGSA-SSAADSVGHDIITEQP ANOCA879_PE7 NOISO EGLEDDSETRSEVSNTSFAASMKSELNSELASSDI-----PTATNSVADSSGHDIITEQP BOVIN6_123_PE7 NOISO -PLEDDSEPRSEGSSPAFSASVKGEVGGELAA-SSGISTPGSA-SSAADSVGHDIITEQP CALJA3_197_PE1 ISOFORMIN -ALEDDSESRSDVSSSAFAASVKDEISGELTA-SSGVSTPGS--------AGHDIITEQP CALJA3_197_PE2 ENSCJAG00000014069 -ALEDDSESRSDVSSSAFAASVKDEISGELTA-SSGVSTPGS--------AGHDIITEQP CANFA3_66_PE9 NOISO -ALDDDSESRSEGSSPAFTASVKGEIGGELAA-SSGVSTPGSA-SSATDSVGHDIITEQP CAVPO166_3_PE1 NOISO -ALEDDSESRSDTSSSAFAASVKGEISGELAA-ASGVSTPGS--------VGHDIITEQP CHICK4_PE1373 ENSGALG00000015635 -GLEDDPETRSDVSAASFAASVKGEITSELAS-SSGVSTAGSVGSSAADPTGHDIITEQP CHICK4_PE1374 ISOFORMIN -GLEDDPETRSDVSAASFAASVKGEITSELAS-SSGVSTAGSVGSSAADPTGHDIITEQP CIOIN5Q_4_PE92 ENSCING00000012200 -----------TPALI-------------YYH-S---------------------IKQTE CIOSAREFTIG_48_4_PE28 ENSCSAVG00000011198 ---FSECAHCSVTGAITFCCTCKPITSIAYLF-NLLIL-------CQNSCLAPSVLTREQ CIOSAREFTIG_48_4_PE30 ISOFORMIN ---FSECAHCSVTGAITFCCTCKPITSIAYLF-NLLIL-------CQNSCLAPSVLTREQ CIOSAREFTIG_48_4_PE31 ISOFORMIN -----KCAHCSVTGAITFCCTCKPITSIAYLF-NLLIL-------CQNSCLAPSVLTREQ DANRE1_43_PE16 NOISO -GLEDDPE-RAEVTTGSFTASVGGDSSSEAPS---SS--------GVSSLGTSDIITEQP DIPORGS_6403_PE1 NOISO -ALEDDSESRSDVSSAAFAASVKGEIGGELAA-SPGVSTPGS--------VGHDIITEQP ECHTEGS_8301_PE1 NOISO XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXX-------XXXXXXXXXX FELCAGS_590_PE5 NOISO -ALEDDSESRSEGSSPAFAASVKGEIGGELAA-SSGVSTPGS--------AGHDIITEQP FUGRU62_1_PE15 ENSTRUG00000005174 -ALEDDPE-KTDVTTGYFTASKR----CLLDSSAVGA--------DNSSAAQVDIITQQP FUGRU62_1_PE16 ISOFORMIN -ALEDDPE-KTDVTTGYFTA--------------VGA--------DNSSAAQVDIITQQP GASACGROUPIX_12_PE29 ENSGACG00000018347 -GLDDDAE-RTEVTTGVFTA------------AVVGA--------DGSSAAQVDIITEQP GASACGROUPIX_12_PE30 ISOFORMIN -GLDDDAE-RTEVTTGVFTA------------AVVGA--------DGSSAAQVDIITEQP GORGO4_4_PE8 ENSGGOG00000016385 RCLKDAQLSCISASSGCCAASVKDEISGELAA-SSGVSTPGS--------AGHDIITEQP GORGO4_4_PE9 ISOFORMIN --------------------SVKDEISGELAA-SSGVSTPGS--------AGHDIITEQP HORSE3_121_PE1 NOISO -ALEEDSESRSDSSSPAFAASVKGEIGGELAA-SSGVSTPGSA-SSAADSAGHDIITEQP HS4_PE336 ENSG00000197386 -ALEDDSESRSDVSSSALTASVKDEISGELAA-SSGVSTPGS--------AGHDIITEQP LOXAF18_3_PE1 ENSLAFG00000013021 -PLEDDSESRSDVSSSTFSASVKGEITGELAA-SSGVSTPGSV-SSAADSTGHDIITEQP LOXAF18_3_PE2 ISOFORMIN -PLEDDSESRSDVSSSTFSASVKGEITGELAA-SSGVSTPGSV-SSAADSTGHDIITEQP MACMU1_1_PE10 NOISO -ALEDDSESRSDVSSSAFAASVKDDISGELAT-SSGVSTPGS--------AGHDIITEQP MICMUGS_1602_PE2 NOISO -ALEDDSESRSDASSSAFAXXXXXXXXXXXXXXXXXXXXXXXXXXX---------XXXXX MONDO5_236_PE5 ENSMODG00000003615 -GLEDDPESRSEVSSATFAASMKSEITGELAS-SSGVSTPVST-SSAADSTGHDIITEQP MONDO5_236_PE6 ISOFORMIN -GLEDDPESRSEVSSATFAASMKSEITGELAS-SSGVSTPVST-SSAADSTGHDIITEQP MOUSE5_PE653 ENSMUSG00000029104 -ALEDDSESRSDVSSSAFAASVKSEIGGELAA-SSGVSTPGS--------VGHDIITEQP MOUSE5_PE654 ISOFORMIN -ALEDDSESRSDVSSSAFAASVKSEIGGELAA-SSGVSTPGS--------VGHDIITEQP MYOLUGS_2052_PE1 NOISO -ALEEDSESRSEGSSPAFAASVKGEICGELAA-SSGVSTPGS--------AGHDIITEQP ORYLA1_40_PE1 NOISO -GLEDEAE-KSEVPAAAFTAP--------------CV--------DGSSVSQVDIITEQP OTOGAGS_4539_PE1 NOISO XXXXXXXXXXXXXX---XXXXXXXXXXXXXXX-XXXXXXXXXX-X-----XXXXXXXXXX PANTR4_4_PE11 NOISO -ALEDDSESRSDVSSSALTASVKDEISGELAA-SSGVSTPGS--------AGHDIITEQP PIG8_2_PE5 NOISO -ALEDEPASRSEGSSPALTASVTGELGGELAP-SSGVSTPGSA-SSAADSVGHDIITEQP POEGU4_64_PE9 NOISO ------------------------------------------------------------ PONPY4_4_PE8 NOISO -ALEDDSESRSDVSSSALAASVKDEISGELAA-SSGVSTPGS--------AGHDIITEQP PROCAGS_7171_PE1 NOISO -ALEDDAESRSDVSGSGFAGSVKGEMTGELAA-SSGVSTPGS--------AGHDIVTEQP PTEVAGS_485_PE5 NOISO -TLEDDSESRSEASSPAFTASAKGEIGGELAA-SSGVSTPGS--------AGHDIITEQP RABITUN0098_2_PE1 NOISO -ALEDDSESRSDVSSSAFAASVKSEIGGELAA-SSGVSTPGA--------SGHDIITEQP RAT14_PE728 ENSRNOG00000011073 -ALEDDSESRSDVSSSAFAASVKSEIGGELAASSSGVSTPGS--------VGHDIITEQP RAT14_PE729 ISOFORMIN -ALEDDSESRSDVSSSAFAASVKSEIGGELAASSSGVSTPGS--------VGHDIITEQP RAT14_PE730 ISOFORMIN -ALEDDSESRSDVSSSAFAASVKSEIGGELAASSSGVSTPGS--------VGHDIITEQP SORARGS_2621_PE1 NOISO -ALEDDTEPRSEGSSPAFTASVKGEIGGELAA-SSGLSTPGS--------ASHDIITEQP SPETRGS_688_PE4 NOISO -ALEDDSESRSDVSSSAFAASVKGEIGGELAA-ASGVSAPGS--------VGHDIITEQP TARSYGS_7946_PE1 NOISO -ALEDDSESRSDVSSSAFAASVKSEIGGELAA-SSGVSTPGS--------VGHDIITEQP TETNG18_PE387 ENSTNIG00000012050 -GLEDDPE-RAEVATGSFTGEFGSFICSFLSASVVGA--------DNPSAAQVDIITEQP TUPGBGS_5468_PE1 NOISO -ALDDDSESRSDVSSSAFAASVKGEIGGELTA-SSGVSTPGS--------AGHDIITEQP TURTRGS_3325_PE1 NOISO -ALEDDSESRSDGSSPTFSASVKGEIGGELAA-SSGVSTPGSA----ADSVGHDIITEQP MATCH CONSENSUS ??L?D??E?????????F???????????????????????????????????DIITEQP

AILMEGL192487_1_2_PE2 NOISO RS-QHTLQP-DSADLTGCDLAS-----------AATDGDE---EDILSHSSSQISAVPSD ANOCA879_PE7 NOISO RS-QHTLQS-ES-DLTNCELTS-----------SANKGDT--DDDVLSRSSSQISTVQSD BOVIN6_123_PE7 NOISO RS-QHTLQT-DAVDLAACDLTS-----------AATDGDE---EDILSHSSSQMSAVPSD CALJA3_197_PE1 ISOFORMIN RS-QHTLQA-DSVDLAGCDLTS-----------SATDGDE---EDILSHSSSQVSAVPSD CALJA3_197_PE2 ENSCJAG00000014069 RS-QHTLQA-DSVDLAGCDLTS-----------SATDGDE---EDILSHSSSQVSAVPSD CANFA3_66_PE9 NOISO RS-QHTLQP-DSVDLTSCDLAS-----------AATDGDE---EDILSHSSSQISAVPSD CAVPO166_3_PE1 NOISO RS-QHTLQA-DSVDLSSCDLTS-----------AATDGDE---EDILSHSSSQISAVPSD CHICK4_PE1373 ENSGALG00000015635 RS-QHTLQS-DSVDLSSCDLTS-----------TATEGED---DDVLSRSSSQISAVQSD CHICK4_PE1374 ISOFORMIN RS-QHTLQS-DSVDLSSCDLTS-----------TATEGED---DDVLSRSSSQISAVQSD CIOIN5Q_4_PE92 ENSCING00000012200 YS--------------------------------------SLKIAQISIAVSSLSSLASS CIOSAREFTIG_48_4_PE28 ENSCSAVG00000011198 YISDMSPSPGLVVRCITANI-------------------------------SSLSSLASS CIOSAREFTIG_48_4_PE30 ISOFORMIN YISDMSPSPGLVVRCITANI-------------------------------SSLSSLASS CIOSAREFTIG_48_4_PE31 ISOFORMIN YISDMSPSPGLVVRCITANSVVNIWENILLAIHDLQRIFIDILANVLLYNIQHIYSLASS DANRE1_43_PE16 NOISO RSSQHALQPGDSVDLSASEQGVGP---------DTPDEED--EEDMLSRSSSGGAGLVST DIPORGS_6403_PE1 NOISO RS-QHTLQA-DSVDLSGCDLTS-----------AATDGDE---EDILSHSSSQISAVPSD ECHTEGS_8301_PE1 NOISO XX-XXXXXX-XX-XXXXXXXXX-----------XXXXXXX---XXXXXXX---X-XX-XX FELCAGS_590_PE5 NOISO RS-QHTLQP-DSVDLTGSDLAS-----------AATDGDE---EDILSHSSSQISAVPSD FUGRU62_1_PE15 ENSTRUG00000005174 RSSQHTIQPGDSVDLSASSEQGGRGGGASASDTPESPNDE---EDMLSRSSSCGANITPE FUGRU62_1_PE16 ISOFORMIN RSSQHTIQPGDSVDLSASSEQGGRGGGASASDTPESPNDE---EDMLSRSSSCGANITPE GASACGROUPIX_12_PE29 ENSGACG00000018347 RSSQHTLQPGDSVDLSASSEQC--GGGASASDTPESPNDN--EEEMLSRSSSGGANVTPE GASACGROUPIX_12_PE30 ISOFORMIN RSSQHTLQPGDSVDLSASSEQC--GGGASASDTPESPNDN--EEEMLSRSSSGGANVTPE GORGO4_4_PE8 ENSGGOG00000016385 RS-QHTLQA-DSVDLASCDLTS-----------SATDGDE---EDILSHSSSQVSAVPSD GORGO4_4_PE9 ISOFORMIN RS-QHTLQA-DSVDLASCDLTS-----------SATDGDE---EDILSHSSSQVSAVPSD HORSE3_121_PE1 NOISO RS-QHTLQP-DSVDLTGCDLTS-----------AATDGDE---EDILSHSSSQISAVPSD HS4_PE336 ENSG00000197386 RS-QHTLQA-DSVDLASCDLTS-----------SATDGDE---EDILSHSSSQVSAVPSD LOXAF18_3_PE1 ENSLAFG00000013021 RS-QHTLQS-DSVDLASCDPAS-----------AATEGDE---EDILSPSSSQISAVPSD LOXAF18_3_PE2 ISOFORMIN RS-QHTLQS-DSVDLASCDPAS-----------AATEGDE---EDILSPSSSQISAVPSD MACMU1_1_PE10 NOISO RS-QHTLQA-DSVDLASCDLTS-----------SATDGDE---EDILSHSSSQVSAVPSD MICMUGS_1602_PE2 NOISO XX-XXXXXX-XXXXXXXXXXXX-----------XXXXXXX---XXILSHSSSQVSAVPSD MONDO5_236_PE5 ENSMODG00000003615 RS-QHTLQS-DPVDLTGCDLTS-----------AATDGDE---EDMLSRSSSQISAVPSD MONDO5_236_PE6 ISOFORMIN RS-QHTLQS-DPVDLTGCDLTS-----------AATDGDE---EDMLSRSSSQISAVPSD MOUSE5_PE653 ENSMUSG00000029104 RS-QHTLQA-DSVDLSGCDLTS-----------AATDGDE---EDILSHSSSQFSAVPSD MOUSE5_PE654 ISOFORMIN RS-QHTLQA-DSVDLSGCDLTS-----------AATDGDE---EDILSHSSSQFSAVPSD MYOLUGS_2052_PE1 NOISO RS-QHTLQP-DSVDLTGCDLAS-----------AATDGDE---EDILSHSSSQISAVPSD ORYLA1_40_PE1 NOISO RSSQHALQPADSVDLSASSEQGG-GGGTSASGTPESPNEN--EEEMLSRSSSGGANAAPE OTOGAGS_4539_PE1 NOISO XX-XXXXXX-X--XXXXXXXX------------XXXXXXX---XXXXXXXXXXXXXXXXX PANTR4_4_PE11 NOISO RS-QHTLQA-DSVDLASCDLTS-----------SATDGDE---EDILSHSSSQVSAVPSD PIG8_2_PE5 NOISO RS-QHTLQP-DSVDLSGCDLSS-----------AATDGDE---EDILSHSSSQMSAVPSD POEGU4_64_PE9 NOISO ------------------------------------------------------------ PONPY4_4_PE8 NOISO RS-QHTLQA-DSVDLAGCDLTS-----------SATDGDE---EDILSHSSSQVSAVPSD PROCAGS_7171_PE1 NOISO RS-QHTLQS-GSVDLASCDLGS-----------AATEGDE---EDILSPSSSQISAVPSD PTEVAGS_485_PE5 NOISO RS-QHTLQP-DSVDLTGCDLTS-----------TATDGDE---EDILSHSSSQVSAVPSD RABITUN0098_2_PE1 NOISO RS-QHTLQA-DSVDLSSCDLTS-----------AATDGDE---EDILSHSSSQISAVPSD RAT14_PE728 ENSRNOG00000011073 RS-QHTLQA-DSVDLSGCDLTS-----------AATDGDE---EDILSHSSSQFSAVPSD RAT14_PE729 ISOFORMIN RS-QHTLQA-DSVDLSGCDLTS-----------AATDGDE---EDILSHSSSQFSAVPSD RAT14_PE730 ISOFORMIN RS-QHTLQA-DSVDLSGCDLTS-----------AATDGDE---EDILSHSSSQFSAVPSD SORARGS_2621_PE1 NOISO RS-QHTLQP-DTVDLSSCDLTS-----------AATDGDE---EDILSLSSSQISAVPSD SPETRGS_688_PE4 NOISO RS-QYTLQT-DSVDLSGCDLAS-----------AATDGDE---EDILSHSSSQVSAVPSD TARSYGS_7946_PE1 NOISO RS-QHTLQA-DSVDLAGCDLTS-----------SATDGDE---EDILSHSSSQVSAVPSD TETNG18_PE387 ENSTNIG00000012050 RSS-HTIQPGDSVDLSAS------------SDTPESPNDN--EEDMLSRSSSCGANLTPE TUPGBGS_5468_PE1 NOISO RS-QHTLQA-DSVDLSSCDLTS-----------AATDGDE---EDILSHSSSQISAVPSD TURTRGS_3325_PE1 NOISO RS-QHTLQT-DSVDLTGCDLTS-----------GATDGDE---EDILSHSSSQISAVPSD MATCH CONSENSUS RS?QHT?Q??D?VDL???????????????????????????????LS?SSS??????S?

AILMEGL192487_1_2_PE2 NOISO PAM------------------DLNDGTQASSPVSDSSQTTTEGPDSAVTPSDSSEIVLDG ANOCA879_PE7 NOISO PTV------------------DLNSGTRASSPISDSSQTTTEGPDSAVTPSDCSEMIIEG BOVIN6_123_PE7 NOISO PAM------------------DLNDGTQASSPISDSSQTTTEGPDSAVTPSDSSEIVLDG CALJA3_197_PE1 ISOFORMIN PAM------------------DLNDGTQASSPISDSSQTTTEGPDSAVTPSDSSEIVLDG CALJA3_197_PE2 ENSCJAG00000014069 PAM------------------DLNDGTQASSPISDSSQTTTEGPDSAVTPSDSSEIVLDG CANFA3_66_PE9 NOISO PAM------------------DLNDGTQASSPVSDSSQTTTEGPDSAVTPSDSSEIVLDG CAVPO166_3_PE1 NOISO AAI------------------DLNDGTQASSPISDSSQTTTEGPDSAITPSDSSEIVLDG CHICK4_PE1373 ENSGALG00000015635 PTM------------------DLNDGTQASSPISDSSQTTTEGPDSAVTPSDSSEIVLEG CHICK4_PE1374 ISOFORMIN PTM------------------DLNDGTQASSPISDSSQTTTEGPDSAVTPSDSSEIVLEG CIOIN5Q_4_PE92 ENSCING00000012200 TIEDKL------------------SC-IRLLPVED----QDP-PSNPLLPHNEQTSQTNG CIOSAREFTIG_48_4_PE28 ENSCSAVG00000011198 TIEEKI------------------SG-IRHVPLED----TKTNQDDPLLPHNNNSAVKNT CIOSAREFTIG_48_4_PE30 ISOFORMIN TIEEKI------------------SG-IRHVPLED----TKTNQDDPLLPHNNNSAVKNT CIOSAREFTIG_48_4_PE31 ISOFORMIN TIEEKI------------------SG-IRHVPLED----TKTNQDDPLLPHNNNSAVKNT DANRE1_43_PE16 NOISO SGDLVTDANQMS------------AGAVSSSPPSESSQTTTEGPDSAVTPSDCAELVLDG DIPORGS_6403_PE1 NOISO PAL------------------DLNDGTQASSPISDSSQTTTEGPDSAVTPSDSSEIVLDG ECHTEGS_8301_PE1 NOISO XXX------------------XXXXXXXXXX---XXXXXXXXXXXXXXX--X-XXXXXXX FELCAGS_590_PE5 NOISO PAM------------------DLNDGTQASSPVSDSSQTTTEGPDSAVTPSDSSEIVLDG FUGRU62_1_PE15 ENSTRUG00000005174 TVEDATPENPAQEGRPVGG----SGAYDHSLPPSDSSQTTTEGPDSAVTPSDVAELVLDG FUGRU62_1_PE16 ISOFORMIN TVEDATPENPAQEGRPVGG----SGAYDHSLPPSDSSQTTTEGPDSAVTPSDVAELVLDG GASACGROUPIX_12_PE29 ENSGACG00000018347 TADYTTPET---EGGPLGEGATLLGANDRSMPPSDSSQTTTEGPDSAVTPSDVAELVLDG GASACGROUPIX_12_PE30 ISOFORMIN TADYTTPET---EGGPLGEGATLLGANDRSMPPSDSSQTTTEGPDSAVTPSDVAELVLDG GORGO4_4_PE8 ENSGGOG00000016385 PAM------------------DLNDGTQASSPISDSSQTTTEGPDSAVTPSDSSEIVLDG GORGO4_4_PE9 ISOFORMIN PAM------------------DLNDGTQASSPISDSSQTTTEGPDSAVTPSDSSEIVLDG HORSE3_121_PE1 NOISO PAM------------------DLNDGTQASSPISDSSQTTTEGPDSAVTPSDSSEIVLDG HS4_PE336 ENSG00000197386 PAM------------------DLNDGTQASSPISDSSQTTTEGPDSAVTPSDSSEIVLDG LOXAF18_3_PE1 ENSLAFG00000013021 PAM------------------DLNDGTQASSPISDSSQTTTEGPDSAVTPSDSSEIVLDG LOXAF18_3_PE2 ISOFORMIN PAM------------------DLNDGTQASSPISDSSQTTTEGPDSAVTPSDSSEIVLDG MACMU1_1_PE10 NOISO PAM------------------DLNDGTQASSPISDSSQTTTEGPDSAVTPSDSSEIVLDG MICMUGS_1602_PE2 NOISO PAM------------------DLNDGTQASSPISDSSQTTTEGPDSAVTPSDSSEIVLDG MONDO5_236_PE5 ENSMODG00000003615 PAV------------------DMNDGTQASSPISDSSQTTTEGPDSAVTPSDSSEIVLDG MONDO5_236_PE6 ISOFORMIN PAV------------------DMNDGTQASSPISDSSQTTTEGPDSAVTPSDSSEIVLDG MOUSE5_PE653 ENSMUSG00000029104 PAM------------------DLNDGTQASSPISDSSQTTTEGPDSAVTPSDSSEIVLDG MOUSE5_PE654 ISOFORMIN PAM------------------DLNDGTQASSPISDSSQTTTEGPDSAVTPSDSSEIVLDG MYOLUGS_2052_PE1 NOISO PAM------------------DLNDGTQASSPLSDSSQTTTEGPDSAVTPSDSSEIVLDG ORYLA1_40_PE1 NOISO TAEYTSSEIAVPEGEEGGAM---LATHDRSLPPSDSSQTTTEGPDSAVTPSDVAELVLDG OTOGAGS_4539_PE1 NOISO XXX------------------XXXXXXXXXXXXXXXSSTTTEGPDSAVTPSDSSEIVLDG PANTR4_4_PE11 NOISO PAM------------------DLNDGTQASSPISDSSQTTTEGPDSAVTPSDSSEIVLDG PIG8_2_PE5 NOISO PAM------------------DLNDGTQASSPVSDSSQTTTEGPDSAVTPSDSSEIVLDG POEGU4_64_PE9 NOISO --------------------------------------------------------VLEG PONPY4_4_PE8 NOISO PAM------------------DLNDGTQASSPISDSSQTTTEGPDSAVTPSDSSEIVLDG PROCAGS_7171_PE1 NOISO PAM------------------DLNDGTQASSPISDSSQTTTEGPDSAVTPSDSSEIXXXX PTEVAGS_485_PE5 NOISO PAM------------------DLNDGTQASSPISDSSQTTTEGPDSAVTPSDSSEIVLDG RABITUN0098_2_PE1 NOISO PAM------------------DLNDGTQASSPISDSSQTTTEGPDSAVTPSDSSEIVLDG RAT14_PE728 ENSRNOG00000011073 PAM------------------DLNDGTQASSPISDSSQTTTEGPDSAVTPSDSSEIVLDG RAT14_PE729 ISOFORMIN PAM------------------DLNDGTQASSPISDSSQTTTEGPDSAVTPSDSSEIVLDG RAT14_PE730 ISOFORMIN PAM------------------DLNDGTQASSPISDSSQTTTEGPDSAVTPSDSSEIVLDG SORARGS_2621_PE1 NOISO PAT------------------DLNDGTQASSPISDSSQTTTEGPDSAVTPSDSSEIXXXX SPETRGS_688_PE4 NOISO PAV------------------DLNDGTQASSPISDSSQTTTEGPDSAVTPSDSSEIVLDG TARSYGS_7946_PE1 NOISO PAM------------------DLNGGTQASSPISDSSQTTTEGPDSAVTPSDSSEIXXXX TETNG18_PE387 ENSTNIG00000012050 TADDATPER----------------AGDHSLPPSDSSQTTTEGPDSAVTPSDVAELVLDG TUPGBGS_5468_PE1 NOISO PAM------------------DLNDGTQASSPISDSSQTTTEGPDSAVTPSDSSEIVLDG TURTRGS_3325_PE1 NOISO PAM------------------DLNDGTQASSPISDSSQTTTEGPDSAVTPSDSSEIVLDG MATCH CONSENSUS ?????????????????????????G???S?P?SDSSQTTTEGPDSAVTPSD??E?VL?G