Alignment of the gene Family HOG000095239 of HOGENOM

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Threshold: 50% 80% 100%
Size: Bigger Smaller Normal
Isoforms are ON
AILMEGL192700_1_1_PE16 NOISO ----------MAAVPQNNLQEQLERHSARKLNNKLSPSKPKSLGFTFKKKI-TSANNVSV ANOCA408_1_PE1 NOISO ------------------------------------------------------------ BOVIN21_23_PE15 NOISO ----------MAAVPQNNLQEQLERHSARKLNNKLSLSKPKSSGFTFKKKV-PSANNVSV CALJA6_18_PE38 ENSCJAG00000009803 ----------MAAVPQNNLQEQLERHSARKLNNKLSLSKPKFSGFTFKKKT-SSDNNVSL CALJA6_18_PE39 ISOFORMIN ------------------------------------------------------------ CALJA6_18_PE41 ISOFORMIN ----------MAAVPQNNLQEQLERHSARKLNNKLSLSKPKFSGFTFKKKT-SSDNNVSL CANFA3_58_PE22 NOISO ----------MAAVPQNNLQEQLERHSARKLSNKLSPSKPKSSVFTFKKK--TSANNVSV CAVPO10_34_PE14 NOISO ----------MAAVPLNNLQEQLERHSARKLNNQSSLSKPKSCGFTFKKKT-SSDNDASI CHICK10_PE561 ENSGALG00000008256 ----------MAAVPQNNLREQLRLHSARGALSKVLPARSRPAAFTFRRTH-SPAAGPA- CHICK10_PE562 ISOFORMIN ------------------------------------------------------------ CHOHOGS_7525_PE1 NOISO -------------------------------------------GFTFKKKT--SENDVSV DANRE18_28_PE5 NOISO TNERASCKYAMSSLPQNNLKEHLERHNN-AAQNKLSLLKPKPGGFCFKKKS-SSGISKVE DASNOGS_6909_PE1 NOISO ----------MAAIPQNNLQEQLERHSARKLNNKLSLSKPKSSGFTFKKKT--SDNEVSV DIPORGS_6396_PE1 NOISO ----------MAALPLNNLQEQLERHSAKKLTNQSSLSKPKPTGFTFKKKT-SSDSDASV ECHTEGS_8292_PE1 NOISO ----------MAAVPQNNLQEQLERHSARKLNNKLSLSKSKPSGFTFKKKT-SFDTDVSI ERIEUGS_8376_PE1 NOISO ----------MAAIPXXXXXXXXXXXXXXXXXXXXXXXXXXXXGFTFRKKV-SSAS---- GASACGROUPXIX_14_PE2 ENSGACG00000010863 ----------MSCLPQNNLKEQLARHSN-AAQSKLSLAKPKPGAFSFKKSS--STTPRVE GORGO15_75_PE1 ENSGGOG00000007710 ----------MAAVPQNNLQEQLERHSARTLNNKLSLSKPKFSGFTFKKKT-SSDNNVSV GORGO15_75_PE2 ISOFORMIN ----------MAAVPQNNLQEQLERHSARTLNNKLSLSKPKFSGFTFKKKT-SSDNNVSV HORSE1_98_PE1 NOISO ----------MAAVPLNNLQEQLERHSARKLNNKLSLSKPKSSGFTFKKKI-SSANDVSV HS15_PE1548 NOISO ----------MAAVPQNNLQEQLERHSARTLNNKLSLSKPKFSGFTFKKKT-SSDNNVSV LAMPAGS_3334_PE4 NOISO ----------MAAVPQNNLQEQLERHSARKLNNKLSLSKPKSSGFTFKKKV-PSANDGSG LOXAF28_17_PE12 NOISO ----------MAAVPQNNLQEQLERHSARKLNDKLSLSKPKSSGFTFKKKT-SSDNDVSI MACEUGS_9520_PE1 NOISO ----------MAVIPQNNLQQQLERHSAKEIQNKLNVLKPKSSGFTFKKKI-PSSNSVTQ MACMU7_73_PE3 NOISO ----------MAAVPQNNLQEQLERHSARTLNNKLSLSKPKFSGFTFKKKT-SSDNNVSV MONDO1_124_PE7 ENSMODG00000019449 ----------MAVIPQNNLQQQLERHSAKEIQNKLNVLRPKSTGFTFKKKI-PPGNSVTH MONDO1_124_PE8 ISOFORMIN ----------MAVIPQNNLQQQLERHSAKEIQNKLNVLRPKSTGFTFKKKI-PPGNSVTH MOUSE7_PE2117 NOISO ----------MAAVPLNNLQEQLQRHSARKLNNQPSLSKPKSLGFTFKKKT--SEGDVSV MYOLUGS_5736_PE1 NOISO ----------MAAVPQNNLQEQLERHSARKLNNKLNLSKPKPSCFTFKKKV-SSANNVSV OCHPRGS_2270_PE1 NOISO ----------MAAVPQNNLQEQLELHSARKLNNRSNLSKPKGSGFTFKRITLFRAHSVSV ORYLA6_13_PE34 NOISO ------------------------------------------------------------ OTOGAGS_5666_PE1 NOISO ----------MAGLPHNNLQEQLERHSARKLNNKLSFSKPKSLGFTFKKKT-PSDNSISL PANTR15_94_PE1 NOISO ----------MAAVPQNNLQEQLERHSARTLNNKLSLSKPKFSGFTFKKKT-SSDNNVSV PIG7_61_PE11 NOISO ------------------------------------------------------------ PIG7_61_PE12 NOISO ------------------------------------------------------------ POEGU10_21_PE29 NOISO ------------------------------------------------------------ PONPY15_91_PE1 NOISO ----------MAAVPQNNLQEQLERHSARTLNNKLSLSKPKFSGFTFKKKT-SLDNNVSV PTEVAGS_3767_PE1 NOISO ----------MAAVPQNNLQEQLERHSARKLNNKLSFSKPKSXXXXXXXXXXXXXXXXXX RABITUN0040_2_PE4 ENSOCUG00000013969 ----------MAAVPQNNLQEQLELHSARKLHNRLNLSKPKSSGFTFKKKA-SSGNSASV RAT1_PE1918 ENSRNOG00000011213 ----------MAAVPLNNLQEQLQRHSARKLKNQFSISKPKPSGFTFKKKT--PEGDVS- RAT1_PE1919 ISOFORMIN ----------MAAVPLNNLQEQLQRHSARKLKNQFSISKPKPSGFTFKKKT--PEGDVS- SORARGS_6804_PE1 NOISO ------------------------------------------------------------ TARSYGS_7935_PE1 NOISO ----------MAAVPQNNLQEQLERHSARRLNNKLSLSKPKSSGFTFKKKT-SSESDVSL TETNG13_PE138 NOISO ----------MSTLPQNNLKEQLARHSN-AAQSKLASTKPKTGPFCFKKKS-SSVTARVD TUPGBGS_2784_PE3 NOISO -------------------------------------------GFTFKKKT-SSDNDVSI TURTRGS_3319_PE1 NOISO ----------MAAVPQNNLQEQLERHSARKLNNKLSPSKPKSSE------I-XSANDVCV XENTR40_1_PE41 NOISO ----------MAALPQNNLQKQLELFSAKGTANKLSLQKPKSSVFTFKKKC-SPNGSLST MATCH CONSENSUS ????????????????????????????????????????????????????????????

AILMEGL192700_1_1_PE16 NOISO TSVSVAKTPVLNDKDVNVAEAVSFSGPP-PLTTSQQTRPSDF-RHAPAGQQTRRAVSKPL ANOCA408_1_PE1 NOISO ------------------------------------------------------------ BOVIN21_23_PE15 NOISO TSVSVAKTPVLSDKDVNITEAFSFSEPL-PHTTNQQTGINDF-KSAPSGPQTKRVGSKPL CALJA6_18_PE38 ENSCJAG00000009803 TNVSVAKTPVLRNKDVNVAEHFSFSEPL-PPTTDQ-QRGKDFSKNVPAGQQTQRVGSKPL CALJA6_18_PE39 ISOFORMIN ------------------------------------------------------------ CALJA6_18_PE41 ISOFORMIN TNVSVAKTPVLRNKDVNVAEHFSFSEPL-PPTTDQ-QRGKDFSKNVPAGQQTQRVGSKPL CANFA3_58_PE22 NOISO TSVSVAKTPVLNDKDVNVTEAFPFSEPL-PHATSQQTRPSDL-KNTPAGQQTRRTVSKPL CAVPO10_34_PE14 NOISO TSVSVAKAPVLSDKDVNVSEVFSFTEPP-PHTPNQQTKVNGFFKNATSGQQGQGLGSKPL CHICK10_PE561 ENSGALG00000008256 ---------ALRDKDVNTSLGSGGV--------ARPKDLRVG-PPGA-RP---------- CHICK10_PE562 ISOFORMIN ------------------------------------------------------------ CHOHOGS_7525_PE1 NOISO TSVSVAKTPVLSDKDVNVAEAFSFSEPL-ARATNQQTSIGDF-KNAAVGQQTKRVGSELS DANRE18_28_PE5 NOISO VPQKPERVAP----KVNFFTA-----------PSK--------PKTNTVNPLANPFALN- DASNOGS_6909_PE1 NOISO TSVSVAKTPVLCDKDVNVAEAFSFGEPL-TQATNLQAEISGF-KNAPAGWQTKRTGSKLS DIPORGS_6396_PE1 NOISO ASVSVARTPVLSDKDVNVSKAFSFSQPL-PCAPRQQAGVGSCFKSTPAGQ---GTGVKPL ECHTEGS_8292_PE1 NOISO TSVSVAKTPVLSDKDVNIAEVFSSGEPL-PRTPSQQTSLHDFFTTAQGRQQATRRHSKPM ERIEUGS_8376_PE1 NOISO -SVSVARTPVLSDKDVNAAEAFSSSELS-PHAWRQQAALSGF-SHSPAGPQTPKAGSEPS GASACGROUPXIX_14_PE2 ENSGACG00000010863 VPTKVIGANVLANRNVNVSKNNLVTKSH-LTFPNK--------LERPQKSQISNFVPVN- GORGO15_75_PE1 ENSGGOG00000007710 TNVSVAKTPVLRNKDVNVTKDFSFSEPL-SNTTNQ-QRVKDFFKNAPAGQQTQRVESKSL GORGO15_75_PE2 ISOFORMIN TNVSVAKTPVLRNKDVNVTKDFSFSEPL-SNTTNQ-QRVKDFFKNAPAGQQTQRVESKSL HORSE1_98_PE1 NOISO TSVSVAKTPVLSDKDVNVTEARSFTEPL-PPPPNQQTSISDF-KKAPGGQQTKRIGSKPL HS15_PE1548 NOISO TNVSVAKTPVLRNKDVNVTEDFSFSEPL-PNTTNQ-QRVKDFFKNAPAGQETQRGGSKSL LAMPAGS_3334_PE4 NOISO TSVSVAKTPVLSDKDVNVTEAFSFNEPL-PYTTSQ---QKDLFKNTSAEQQTKRVGSKLL LOXAF28_17_PE12 NOISO TSVSVAKKPVLSDKDAGVAAAVSFSEPL-PHTSSRQTRLHDFLQNAPADQEITRGGSKPL MACEUGS_9520_PE1 NOISO AL-------VLSDKDVNVTETFPLSKPF-LSAKNQQTSIGAFSERTSKGPQIQKFCSNQI MACMU7_73_PE3 NOISO TNVSVAKTPVLRNKDVNVTEDFSLSEPP-PDTTNQ-QRVKDFFKNAPAGQQTQRVGSTPL MONDO1_124_PE7 ENSMODG00000019449 AP-------VLGDKDVNVTETFPLSKAF-FNAKNQQTSISDSSEKTSKAQQIQKFCSNQI MONDO1_124_PE8 ISOFORMIN AP-------VLGDKDVNVTETFPLSKAF-FNAKNQQTSISDSSEKTSKAQQIQKFCSNQI MOUSE7_PE2117 NOISO TSVSVVKTPALSDKDVNVSEAFSFTESP-LHKPKQQAKIEGFFKHFPGRQQSKGTCSEPS MYOLUGS_5736_PE1 NOISO TCVSVAKTPVLSDKDVNVSEDFSFSETL-PHTMNPQTRISDF-KNAAAGQQTKRIGSKPL OCHPRGS_2270_PE1 NOISO TSMSVPGTSVVGRRDGHVTGGFSLSSEPQPRPPD--EECADSLRNARTSQQTQGAGAS-- ORYLA6_13_PE34 NOISO ------------------------------------------------------------ OTOGAGS_5666_PE1 NOISO TSM-----------SDNVTEAFSVSEPP-SHTTNQQTKINDFYKNAPAGQQTQRVGSKPL PANTR15_94_PE1 NOISO TNVSAAKTPVLRNKDVNVTEDVSFSEPL-PNTTNQ-QRAKDFFKNAPAGQQTQRVGSKSL PIG7_61_PE11 NOISO ------------------------------------------------------------ PIG7_61_PE12 NOISO ------------------------------------------------------------ POEGU10_21_PE29 NOISO ------------------------------------------------------------ PONPY15_91_PE1 NOISO TNVSVAKTPVLRNKDVNVTEDFSFSEPL-PNTTNQ-QRIKDFFKNAPAGQQTQRVESKPL PTEVAGS_3767_PE1 NOISO XXXXXXXXXXXXXXXXX---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTKRAGSQPL RABITUN0040_2_PE4 ENSOCUG00000013969 TSVSAARTPVLSDKDVNVTEGSSFSEPQ-ACPAGPPARINDFFKNAPAGLQSRGAGSTPL RAT1_PE1918 ENSRNOG00000011213 ----VVRTPVLSDKDVNMSEALSYTEPP-LHKPKQQSNIDGFFKNSPGGQQSKETCSELS RAT1_PE1919 ISOFORMIN ----VVRTPVLSDKDVNMSEALSYTEPP-LHKPKQQSNIDGFFKNSPGGQQSKETCSELS SORARGS_6804_PE1 NOISO -------------------------------TSSQPARVSDL--NAPESHRSKTVGSEPS TARSYGS_7935_PE1 NOISO TSVSVAKMPVLSNKDVNVTEDFSFSEPL-SHIKNQSTRISDVFKNAPEGQQTQRLASKPS TETNG13_PE138 NOISO IPTKVT--EVFQSRDVNVFRNNLVTNSP-LTFSNK--------LERSQTSKISTFFAVN- TUPGBGS_2784_PE3 NOISO TNVSVAKTPVLSDKDVNVSEAFSFSEPL-SHATDQQIKINELSKNAPAGQQPSRVGSKPS TURTRGS_3319_PE1 NOISO TSVSVAKAPVMK--DVTITEAFSFSEPF-PHTTNQQTKINDF-KNTPAGQQTKRVGSKPL XENTR40_1_PE41 NOISO GFVEVKQNVALKDKNVNVKQND--V----------QTNLTVL-PKSAERNKINGFFTPVY MATCH CONSENSUS ????????????????????????????????????????????????????????????

AILMEGL192700_1_1_PE16 NOISO SP-DVLQVQRGVLGNTQNTP----------TVKKSSNATFKKLEFSSSSDSFVTINDWDD ANOCA408_1_PE1 NOISO ------------------------------------------------------------ BOVIN21_23_PE15 NOISO LP-SLSQVPQEVSCTAQNTP----------VIKQSLNATFKKLEFSSSSDSLIAFNDWDD CALJA6_18_PE38 ENSCJAG00000009803 LP-DFLQTPKEVLCTTQNTP----------TLEKSRDTAFKKLEFSSSPDSLSTINDWDD CALJA6_18_PE39 ISOFORMIN ------------------------------------------------------------ CALJA6_18_PE41 ISOFORMIN LP-DFLQTPKEVLCTTQNTP----------TLEKSRDTAFKKLEFSSSPDSLSTINDWDD CANFA3_58_PE22 NOISO LP-DLSLV-SRVLCNTQNTP----------IVKKSSNATFKKLEFSSSSDSFVTINDWDD CAVPO10_34_PE14 NOISO LV-DLLKTSQEALPATRNTS----------AIKKPYDAVLKKLEFSSSQDSFCTMDDWDD CHICK10_PE561 ENSGALG00000008256 ----ALPGPAGSSG-----PTAGAPP------------GSVSVSLPSSGPAAYTGDEWDD CHICK10_PE562 ISOFORMIN ------------------------------------------------------------ CHOHOGS_7525_PE1 NOISO SP-DLLRFSQEVLCTVQNTP----------VTKEPRDATFK-LEFSSSTDSFITVNDWDD DANRE18_28_PE5 NOISO --KTPL--VQSTIKA---LPKSAALP-------KDSTNDQTVELKHD--ISQLSFNEWDD DASNOGS_6909_PE1 NOISO SP-DLLQFSPEVLCTTQNTP----------VIKEPRDVIFKKLELSSSTDSFAAINDWDD DIPORGS_6396_PE1 NOISO SP-GLLRSPPA-VPSGQNTP----------AARIPQDAAFKKLEFSSSPDSSSSPSHWDD ECHTEGS_8292_PE1 NOISO PP-DFLQTPQESVYTAQGTL----------ATREAQDVTFKKLEFNSSTDSAMAIDDWDD ERIEUGS_8376_PE1 NOISO SA-DLLHTPQGAFCTTQNTP----------AVKASRGSTMKKLEVSSSSDSFLLPNEWDD GASACGROUPXIX_14_PE2 ENSGACG00000010863 --SKSNRAPAAV-SS---IP---HNQ-------FTGGNGSKSRSLDT--SLGFPMDDWDD GORGO15_75_PE1 ENSGGOG00000007710 LP-DFLQTPKEVLCTTQNTP----------TIKKSRDTALKKLEFSSSPDSLSTINDWDD GORGO15_75_PE2 ISOFORMIN LP-DFLQTPKEVLCTTQNTP----------TIKKSRDTALKKLEFSSSPDSLSTINDWDD HORSE1_98_PE1 NOISO LP-DLLQFPQEVLCTTQKTP----------VVKKSRDATFKKLEFSSSSDSFITINDWDD HS15_PE1548 NOISO LP-DFLQTPKEVVCTTQNTP----------TVKKSRDTALKKLEFSSSPDSLSTINDWDD LAMPAGS_3334_PE4 NOISO LP-DLSPVPQEVLCATQNTP----------VIKESCDSTFKKLEFSSSSDSFTAFNDWDD LOXAF28_17_PE12 NOISO SP-DLLQTPGEVSCTARNTP----------AVRESHDVTCKKLKFSSSTASLITINDWDD MACEUGS_9520_PE1 NOISO -----LS---NSSKNTHKTSCSLQPPTKENSVDKELCRDSKKLELNSSFDSAILVNDWDD MACMU7_73_PE3 NOISO LP-DFLQTPKEVLCTTQNTP----------TVKKSQNTALKKLEFSSSPDSFRTINDWDD MONDO1_124_PE7 ENSMODG00000019449 -----LL---NSSKNTQETSKVSQPPTKENCVKKELCKDSKILETNSSFDS-ILVNDWDD MONDO1_124_PE8 ISOFORMIN -----LL---NSSKNTQETSKVSQPPTKENCVKKELCKDSKILETNSSFDS-ILVNDWDD MOUSE7_PE2117 NOISO LP-ATVQTAQDTLCTTPKTP----------TAKKLPVAVFKKLEFSSSADSL---SDWAD MYOLUGS_5736_PE1 NOISO LP-DSSQIPREVSLATQSTP----------SRKEFRDATFKKLEYSSS-------SDWDD OCHPRGS_2270_PE1 NOISO ------QPPQPTSWPSQNGA----------GAKNTWHTVFRNWNSSSSPDSLSALHGWAD ORYLA6_13_PE34 NOISO ------------------------------------------------------------ OTOGAGS_5666_PE1 NOISO LP-DLVQIPKEVLCTTPHTS----------VIKKPSDAAFKKLEFSSSSDSFGAIDNWDD PANTR15_94_PE1 NOISO LP-DFLQTPKEVLCTTQNTP----------TVKKSRDTALKKLEFSSSPDSLSTINDWDD PIG7_61_PE11 NOISO ------------------------------------------------------------ PIG7_61_PE12 NOISO ------------------------------------------------------------ POEGU10_21_PE29 NOISO ------------------------------------------------------------ PONPY15_91_PE1 NOISO LP-DFLQTPKEVLCTTQNTP----------TVKKSWDTALKRLEFSSSPDSLSTINDWDD PTEVAGS_3767_PE1 NOISO LA-DLV---QEVLHTTQSTP----------IIKESRDPTFKKLEFSSSSDSFITINNWDD RABITUN0040_2_PE4 ENSOCUG00000013969 LP-DVSQTPQEASCTPRLAP----------AAKTPRDTVFKKLDFSSSLDSLGALNGWDD RAT1_PE1918 ENSRNOG00000011213 LP-EVVQIPQDASCTTPKTP----------AVKKPHVAIFKKLEFSSSADSL---SDWAD RAT1_PE1919 ISOFORMIN LP-EVVQIPQDASCTTPKTP----------AVKKPHVAIFKKLEFSSSADSL---SDWAD SORARGS_6804_PE1 NOISO LQ-EMWSAPPEESYPTQNTP----------LTKGSRDATFKKLEFSSSSDSFLTTTGWDD TARSYGS_7935_PE1 NOISO -----LQIPKEVLCTTQNTP----------VIKKSRDAAFKTLEFSSSSDSFNAIDDWDD TETNG13_PE138 NOISO --SKTRSDSTSQIDN---LASSGQIS-------SATAKPDGSTSLDA--SLGFPEDNWDD TUPGBGS_2784_PE3 NOISO W-----QIPQEVLCTLQNTP----------VTKKPHDAAFKKLEFSSSLDSFSTINDWDD TURTRGS_3319_PE1 NOISO LP-NLSQVPQEVLCTTQNTL----------LVKESRDATFKKLEFSSSSDSLITFSDWDD XENTR40_1_PE41 NOISO TKSTQLPQTVAVKDHVHINDSANKHPRVE-------DSASKKTGINTSFGSVTSLEEWDD MATCH CONSENSUS ?????????????????????????????????????????????????????????W?D

AILMEGL192700_1_1_PE16 NOISO MDDFDTSGNSKAFVTPCRNHF-VRVSTAQKSKKSKRNFLKAQLPEANTV---------TA ANOCA408_1_PE1 NOISO ------------------------------------------------------------ BOVIN21_23_PE15 NOISO MDDFDTSGNSKAFVTPCKNHF-VRVSTAQKSKKSKRNLVKAQLNKTHTG---------ET CALJA6_18_PE38 ENSCJAG00000009803 MDDFDTSGTSKAFVTPPQSHF-VRVSTAQKSKKAKRNFFKAQLCATNTV---------KA CALJA6_18_PE39 ISOFORMIN ------------------------------------------------------------ CALJA6_18_PE41 ISOFORMIN MDDFDTSGTSKAFVTPPQSHF-VRVSTAQKSKKAKRNFFKAQLCATNTV---------KA CANFA3_58_PE22 NOISO MDDFDTSGNSK-LVTPCKNHF-VRVSTAQKSKKPKRNFLKAQLPQANTV---------KA CAVPO10_34_PE14 NOISO LDDFDTSETSKVFATPPKNHL-IRVSTAQKSKKAKRIFVKAPPHKTSIV---------KA CHICK10_PE561 ENSGALG00000008256 MDDFDLSGFEKKFSR--------------------------------PAVLSPK------ CHICK10_PE562 ISOFORMIN ------------------------------------------------------------ CHOHOGS_7525_PE1 NOISO MDDFDISGNSKAFVTPPKSHF-LRVSTAQKSKKAKRNFFKIQLPKTNTV---------KA DANRE18_28_PE5 NOISO LDDFETPVKSRVASPVAGTST-KKPSVSDQN------TSSSCSSKCEETKVNEESQATET DASNOGS_6909_PE1 NOISO MDDFDISN-SKAFVTPPKSHF-VRISTAQKSKKAKRNFFKIQLPKTNTV---------KA DIPORGS_6396_PE1 NOISO RDDFDTSSASKAFATPARGRF-VRVSTAQKSRQGKRNFVKASPHKALAV---------QV ECHTEGS_8292_PE1 NOISO MDDFDISGTSKAFVTPLRTHN--RVSTAXXXXXXXXXXXXXXXXXXXXX---------XX ERIEUGS_8376_PE1 NOISO MDDFDTSGNSKAFVTPPKNHF-VRVSTAQKSKKSKRNFFKAPRPKANKV---------EI GASACGROUPXIX_14_PE2 ENSGACG00000010863 LDDFEIPVKNDSGMSANQVS------LFNEE------RA------------------QSS GORGO15_75_PE1 ENSGGOG00000007710 MDDFDTSETSKSFVTPPQSHF-VRVSTAQKSKKGKRNFFKAQLYTTNTV---------KT GORGO15_75_PE2 ISOFORMIN MDDFDTSETSKSFVTPPQSHF-VRVSTAQKSKKGKRNFFKAQLYTTNTV---------KT HORSE1_98_PE1 NOISO MDDFDTSGSSKAFVTPSRNHS-VRVSTAQKCKKSKRTFLKAQLPKANSV---------KA HS15_PE1548 NOISO MDDFDTSETSKSFVTPPQSHF-VRVSTAQKSKKGKRNFFKAQLYTTNTV---------KT LAMPAGS_3334_PE4 NOISO MDDFDTSRNSKAFVTPHKNHF-VRVSTAQKSKKSKRNFLKAQLDKTDTV---------KV LOXAF28_17_PE12 NOISO MDDFDISGNSEAFVTPLRTHN-VRISTAQKSKKGKRNFLKSQLHKADVV---------KV MACEUGS_9520_PE1 NOISO IDDFDTSGNSKTFTTPSRTRF-TKLSNTQKSKGDKNNISNTWMSKANGKKVDPE------ MACMU7_73_PE3 NOISO MDDFDTSGTSKAFVTPPQSHF-VRVSTAQKSKKAKRNFFKAQLYTTNTV---------KA MONDO1_124_PE7 ENSMODG00000019449 IDDFDTSGNSKTFTTPSRTHF-TKLNNTQRSKTDKNNLSKT---QTSGKKIDPE------ MONDO1_124_PE8 ISOFORMIN IDDFDTSGNSKTFTTPSRTHF-TKLNNTQRSKTDKNNLSKT---QTSGKKIDPE------ MOUSE7_PE2117 NOISO MDDFDMSA-SDAFASLAKNPA-TRVSTAQKMKKTKRNFFKPPPRKANAV---------KT MYOLUGS_5736_PE1 NOISO MDDFDTSGNSKAFVTPLKNHS-VRVSTAQK--KSKRNFLKAQLQKEDTV---------KV OCHPRGS_2270_PE1 NOISO MIDFDPSRTPKALPTPSRKPG-VRVSTAQKPKRAKKNFCKPSTTRS-------------- ORYLA6_13_PE34 NOISO ------------------------------------------------------------ OTOGAGS_5666_PE1 NOISO MDDFDTSGTSKAFVTPLKNHFLLRVSTAQKSKKAKRNFSKEQLYKTDTV---------KA PANTR15_94_PE1 NOISO MDDFDTSETSKSFVTPPQSHF-VRVSTAQKSKKGKRNFFKAQLYTTNTV---------KT PIG7_61_PE11 NOISO ------------------------------------------------------------ PIG7_61_PE12 NOISO ------------------------------------------------------------ POEGU10_21_PE29 NOISO ------------------------------------------------------------ PONPY15_91_PE1 NOISO MDDFDTSETSKSFVTPPQSHF-VRVSTAQKSKKGKRNFFKAQLYTTNTV---------KA PTEVAGS_3767_PE1 NOISO MDDFDTSGNSKAFVTPLRNHF-VRVSTAQKSKKSKRNFFKAHLHKANTV---------KV RABITUN0040_2_PE4 ENSOCUG00000013969 MDDFDTSGTPKAFAASPRKPV-ARVSTAQKSKRAKRNFCKAQLKKADAA---------EA RAT1_PE1918 ENSRNOG00000011213 IDDFDVPA-SDAFVSLTRNPT-TRVSTAKKLSSSKRNFFKPPPRA-SAV---------KA RAT1_PE1919 ISOFORMIN IDDFDVPA-SDAFVSLTRNPT-TRVSTAKKLSSSKRNFFKPPPRA-SAV---------KA SORARGS_6804_PE1 NOISO MDDFDISGDSKAFITPSRNHF-IKVSTAQKSKVSKRNLSKAPLRKTSTL---------KA TARSYGS_7935_PE1 NOISO MDD-DTTGTSKAFVTPSRNHF-VRVSTAQKSKKAKRNFLKAQLYKTNTV---------NI TETNG13_PE138 NOISO LDDFEIPVKEPEEILGEKEQ------SSAET------GA-------PGHSVQD-VAAVSP TUPGBGS_2784_PE3 NOISO MDDFVTSGSSKAFVTPSKDHF-VRVSTAQKSKRAKRNFSKAELPKTNTE---------KA TURTRGS_3319_PE1 NOISO MDDFDTSGDSKAFVTPRQNHF-IRVSTAQKSKKSKRNFLKAHLGKTNTV---------KT XENTR40_1_PE41 NOISO LDDFDTSVSPPKSQAGKIKIT-P-QNC----KNTSPVSSK-------IQCLSPK------ MATCH CONSENSUS ?DDF????????????????????????????????????????????????????????

AILMEGL192700_1_1_PE16 NOISO DLTPSSSESKQ----ACLTKKQN---------NDSEWF---SNDVICIDDDPN--PE-EL ANOCA408_1_PE1 NOISO ------------------------------------------------------------ BOVIN21_23_PE15 NOISO DLAPSSSESKQ----EHLTEKQK---------DDSEWL---SSDVICIDDDPD--PE-EL CALJA6_18_PE38 ENSCJAG00000009803 DLPP-SSESKQ----IDLTVEQK---------DDSEWF---SSDVICIDDGPIA---EVH CALJA6_18_PE39 ISOFORMIN ------------------------------------------------------------ CALJA6_18_PE41 ISOFORMIN DLPP-SSESKQ----IDLTVEQK---------DDSEWF---SSDVICIDDGPIA---EVH CANFA3_58_PE22 NOISO DLTPSSFESKQ----ACLTKKQN---------DDSEWF---SNDVICIDDDPN--PE-EL CAVPO10_34_PE14 NOISO DLTQSESQ-PV----VDLTKEEK---------HDLKWL---KSSMICIDDDSV--PQ-VL CHICK10_PE561 ENSGALG00000008256 GPRTPQGRGLR----VSKARADV--GPQEHGAEVSCSQGSSQGSLICLGDAGAP-AAAVL CHICK10_PE562 ISOFORMIN ------------------------------------------------------------ CHOHOGS_7525_PE1 NOISO DLSPSSE-NKQ----VDLTKEQQ---------DDSEWL---SNGVICIDGDPIS---KGL DANRE18_28_PE5 NOISO ITAP--KDVLSAANGVSTETAER--EPEDSPIK---KSKRPKKSV--------Q-HTALL DASNOGS_6909_PE1 NOISO DLASSSSENKQ----VDLTKEQQ---------DDSEWL---SSGVICIDDDPIP---EGL DIPORGS_6396_PE1 NOISO DLTSS-SESQQ----IDLTEEQK---------DETESF---RSAVICIDEDSTS---DVL ECHTEGS_8292_PE1 NOISO XXXXXXXXXXX----XXXXXXXX---------XXXXXX---XXXXXXXXXXXXX---XXX ERIEUGS_8376_PE1 NOISO NLTLSSE-SSH----IHSAKEQK---------GALEWS---HSGVICIDDDSQ--HE-EF GASACGROUPXIX_14_PE2 ENSGACG00000010863 LTKPPLSNCLENGNGLSRSEQ---------SFM---ETDELEHQV--------R-NAAAS GORGO15_75_PE1 ENSGGOG00000007710 DLPPPS-ESEQ----IDLTEEQK---------DDSEWL---SSDVICIDDGPIA---EVH GORGO15_75_PE2 ISOFORMIN DLPPPS-ESEQ----IDLTEEQK---------DDSEWL---SSDVICIDDGPIA---EVH HORSE1_98_PE1 NOISO DLTPSSSEIEQ----VDLTKK-Q---------DDSEWL---SSDVICIDDGPN--SK-EL HS15_PE1548 NOISO DLPPPSSESEQ----IDLTEEQK---------DDSEWL---SSDVICIDDGPIA---EVH LAMPAGS_3334_PE4 NOISO DLTPSSSESKQ----VYLTKKQK---------DDSEWL---RSDVICLDDGPDS---EEL LOXAF28_17_PE12 NOISO DLTSSSAESEQ----VDLTKEQQ---------NDSEWL---SGGVVCIEDDPIS---KRL MACEUGS_9520_PE1 NOISO LLSFPSGKSRQ----AELTKKE------------SSESEELSNPVICLDDDSIS-EEFR- MACMU7_73_PE3 NOISO DLPPSFSESEQ----IDLTKEQK---------DDSEWL---SSDVICIDDGPIG---EVH MONDO1_124_PE7 ENSMODG00000019449 LLNFPSGKSRQ----VELTRKE------------LPESEELNSPVICLDD-YVS-EEVR- MONDO1_124_PE8 ISOFORMIN LLNFPSGKSRQ----VELTRKE------------LPESEELNSPVICLDD-YVS-EEVR- MOUSE7_PE2117 NOISO DLTPPSPECLQ----VDLTKESEEEEEEEEEAEGADCL---SRDVICIDNDSAS---EEL MYOLUGS_5736_PE1 NOISO DLTTPPSECKQ----VDLTEEQK---------ADSEWLSSLSSGVICIDDGPSS---EEL OCHPRGS_2270_PE1 NOISO GSSPASMACKQ----VDLTEKDW---------GDSSWL---GGSVICINDDDDDDSISQV ORYLA6_13_PE34 NOISO ------------------------------------------------------------ OTOGAGS_5666_PE1 NOISO GLTTSSSENKQ----VDFTKGQK---------DDSERL---SSDVICIDDDCIS---EVR PANTR15_94_PE1 NOISO DLPPPSSETEQ----IDLTEEQK---------DDSEWL---SSDVICIDDGPIA---EVH PIG7_61_PE11 NOISO ------------------------------------------------------------ PIG7_61_PE12 NOISO ------------------------------------------------------------ POEGU10_21_PE29 NOISO ------------------------------------------------------------ PONPY15_91_PE1 NOISO DLPPPSSESEQ----IDLTEEQK---------DDSEWL---SSDVICIDDGPIA---EVH PTEVAGS_3767_PE1 NOISO DLTSSSSESKQ----VYSTKEQK---------ADSKWL---NSGVICIDDSPHS---QEL RABITUN0040_2_PE4 ENSOCUG00000013969 DLTPASAASKP----VELAGAGK---------GDCDGV---GGGVICIDDDDG--PVSQV RAT1_PE1918 ENSRNOG00000011213 DLTPSSPECLQ----VDLTKEQE---------EEADCL---SRDVICIDTDPAS---EEL RAT1_PE1919 ISOFORMIN DLTPSSPECLQ----VDLTKEQE---------EEADCL---SRDVICIDTDPAS---EEL SORARGS_6804_PE1 NOISO YFSPSSPESM----------QQR---------DESGWL---SSDVICIDDSTK-----EL TARSYGS_7935_PE1 NOISO DLTS-SSESKQ----VDLTKEQK---------DDSEWL---SSDVICIDDGPVF---KVP TETNG13_PE138 NOISO GPDPVQEDCVLGDSPVRPSRR---------R-----------RNV--------P-KNRVL TUPGBGS_2784_PE3 NOISO DLNSSLSESKQ----VDLTREEK---------EDSECL---SSDVICISDGPLS---KVL TURTRGS_3319_PE1 NOISO DLTPSSSESKQ----AFLTKKQK---------DDSEWL---NSDVICIDDDPN--SE-EL XENTR40_1_PE41 NOISO GPTIEKQMCAK----KPYENNEI--ASEPQKLVHAQTAEMPDKSLVCLGSVEHT-NLEKD MATCH CONSENSUS ????????????????????????????????????????????????????????????

AILMEGL192700_1_1_PE16 NOISO IHGDAQESQPLKTHLGEERDGSE-KKNL--GETEL-----HSVV-KSPCVELDEDDYETD ANOCA408_1_PE1 NOISO ------------------------------------------------------------ BOVIN21_23_PE15 NOISO INEDTQENHSLKTHLGAERGNCEKKKNL--EETEL-----RSVE-KSSCIELDEDDYDID CALJA6_18_PE38 ENSCJAG00000009803 VNEDAQESDSLKTHLQDERDNNEKKKNV--EEAEL-----HSTE-KVPCIEFDDDDYDID CALJA6_18_PE39 ISOFORMIN ------------------------------------------------------------ CALJA6_18_PE41 ISOFORMIN VNEDAQESDSLKTHLQDERDNNEKKKNV--EEAEL-----HSTE-KVPCIEFDDDDYDID CANFA3_58_PE22 NOISO IHGDPQESHSLKTHLEEERDSYSEKKNW--EETEL-----CSLE-KSPCVELDEDDYDTD CAVPO10_34_PE14 NOISO TSEDTQESKSLNR-LGDERDNNE-KHNE--EDVEL-----YSTE-KATCVEHNDDDY-ID CHICK10_PE561 ENSGALG00000008256 SDNGMEEARAA-----TDGGSGESQKL--SNGEKSSQLEPGDVGNELLADIELEEDDYLD CHICK10_PE562 ISOFORMIN ----------------------------------------------------LEEDDYLD CHOHOGS_7525_PE1 NOISO INEDTQESHSLKIHLRDERDNSEKKKSL--EETEL-----HSNE-KPPCTEFDEDDFNLD DANRE18_28_PE5 NOISO SDTEDEE-----IIHCVSPDTNQKNFKSVAVAEKDKWGEPNVID-SDDCEENNHYEGFED DASNOGS_6909_PE1 NOISO INEDAQESHSLKIHLEDGSDDNEKKQSL--EETEL-----HSVE-KSPCXXXXXXXXXXX DIPORGS_6396_PE1 NOISO LNKDSQESHTSETHLEDERGSRDRKQLV--EGAEP-----PSAQ-QGPCIELD-DDYDVD ECHTEGS_8292_PE1 NOISO XXXXXXXXXXXXXXXXXXXXNSEKKTSL--EETAL-----HPIE-KSPCVELDEDDCCID ERIEUGS_8376_PE1 NOISO LKEETRGSRSPET----------------------------HSE-GSSCVELREEAYDID GASACGROUPXIX_14_PE2 ENSGACG00000010863 PEQCL----------NNEPAEFELDVSPFILDDETKWTDPKVIQ-LYDNSD---PEDDLD GORGO15_75_PE1 ENSGGOG00000007710 INEDAQESDSLKTHLEDERDNSEK-KNL--EEAEL-----HSTE-KVPCIEFDDDDYDTD GORGO15_75_PE2 ISOFORMIN INEDAQESDSLKTHLEDERDNSEK-KNL--EEAEL-----HSTE-KVPCIEFDDDDYDTD HORSE1_98_PE1 NOISO INEDMQESHS----LGEERDSGEKKKNL--EEKEL-----HSIE-KSPCVEFDEDDYDMD HS15_PE1548 NOISO INEDAQESDSLKTHLEDERDNSEKKKNL--EEAEL-----HSTE-KVPCIEFDDDDYDTD LAMPAGS_3334_PE4 NOISO INEDPQENHSLKTHLGEERGDCEKEKNS--KESEL-----PSVE-KSSCIELNEDDYDIE LOXAF28_17_PE12 NOISO VDEETQESDPLKTHLGDEKGNSEKKKSL--QDTEL-----YSVE-KSPRVDLDEDDYDRD MACEUGS_9520_PE1 NOISO -NEGIQESHALKTHLGIERDDNEKKKY--PEGVERH-AVDEPLGAD--CVEFNEDDFDID MACMU7_73_PE3 NOISO INEDAQESDSLKTHLEDERDNSEKKKNL--EEAEL-----HSTE-KVPCIEFDDDDYDID MONDO1_124_PE7 ENSMODG00000019449 -NEDIQESHASKTHLCKERDDNEKKKY--PNGTEQH-AADESLGAD--FAEFNEDDFDID MONDO1_124_PE8 ISOFORMIN -NEDIQESHASKTHLCKERDDNEKKKY--PNGTEQH-AADESLGAD--FAEFNEDDFDID MOUSE7_PE2117 NOISO TEKDTQESQSLKAHLGAERGDSEKKSHE--DEAVF-----HSVQ-NTEYFEHNDNDYDID MYOLUGS_5736_PE1 NOISO ANEDTQNSHSLKTHLGEERXXXXXXXXX--XXXXX-----XXXX-XXXXXXXXXXXXXXX OCHPRGS_2270_PE1 NOISO LIEDSQENQLLETHMGDKKGDSEDQKHL--EVMES-----DCNK-EVPPVDLDDDNYDVD ORYLA6_13_PE34 NOISO ------------------------------------------------------------ OTOGAGS_5666_PE1 NOISO INEDTQESHSLKTHLGDERDNSGKKKNL--EDTEL-----HSTE-KIPYTKLS-DDYDTD PANTR15_94_PE1 NOISO INEDAQESDSLKTHLEDERDNSKKKKNL--EEAEL-----HSTE-KVPCIEFDDDDYDTD PIG7_61_PE11 NOISO ------------------------------------------------------------ PIG7_61_PE12 NOISO ------------------------------------------------------------ POEGU10_21_PE29 NOISO -----------------------------------------------------LEEDDLD PONPY15_91_PE1 NOISO INEDAQESDSLKTHLEDERDNSKKKKNL--EEAEL-----HSTE-KVPCIEFDDDDYDTD PTEVAGS_3767_PE1 NOISO INEDSQDSHSLKTHLREEGDNSEKKKNF--KETEL-----YSIE-KSPCIELDEDDYDID RABITUN0040_2_PE4 ENSOCUG00000013969 LILDSQESHSLETHLGGERDHPEDKKVL--DTVEL-----HSAE-EVPCIELEDDDYDID RAT1_PE1918 ENSRNOG00000011213 LEKDVQEGLSLDARLGTERVDSAKKSHE--DKAAF-----QSPQ-NALYFEHNDNDYDID RAT1_PE1919 ISOFORMIN LEKDVQEGLSLDARLGTERVDSAKKSHE--DKAAF-----QSPQ-NALYFEHNDNDYDID SORARGS_6804_PE1 NOISO TDEDAQESQCLKTPFREEKXXXXXXXXX--XXXXX-----XXXX-XXXXXXXX-XXXXXX TARSYGS_7935_PE1 NOISO TSEDTQKSHSLETHLGDERDNSEKKNNL--EEAEL-----HSTE-KVPCIEFDDDDYNID TETNG13_PE138 NOISO SESDE----------DNADEPCDEAKGDVFLETKSLWIEPKVIE-LDDNSE---PEDDFN TUPGBGS_2784_PE3 NOISO VSEDTHESHSLETQLRDEKNNSEEKENL--EEAEL-----HSTE-NVPCVELDDDDYDID TURTRGS_3319_PE1 NOISO INEDTQENHPLKTHLGEERDNCEKKKNL--EEMEL-----HSFE-KSSCVELDEDDYDID XENTR40_1_PE41 NOISO ------TCRNI-----DYSGTD------------DIEHDQETL---SQALIENEDDCEPD MATCH CONSENSUS ????????????????????????????????????????????????????????????

AILMEGL192700_1_1_PE16 NOISO FVPPSPEEEVISASS--SSLKCFSMLKDLDSSG-----PSTSED-LPTPEGMA-PQ---P ANOCA408_1_PE1 NOISO ------------------------------------------------------------ BOVIN21_23_PE15 NOISO FVPPSPEEGMTSTSS--SSLKCSSMLKDLDTSDKKHS-LSTSED-LSKLKEMATQQ---P CALJA6_18_PE38 ENSCJAG00000009803 FVPPSPEEIISAS-S--SSSKCFSVSKDLDTSDRREDVLGTSKDLLSKPEKMTMQE---P CALJA6_18_PE39 ISOFORMIN ---------------------------------------------------MTMQE---P CALJA6_18_PE41 ISOFORMIN FVPPSPEEIISAS-S--SSSKCFSVSKDLDTSDRREDVLGTSKDLLSKPEKMTMQE---P CANFA3_58_PE22 NOISO FVPPSPE--VISASS--SSLKCFSMLKDLDASGTEDG-PSTSED-LPTPKGMTTQQ---P CAVPO10_34_PE14 NOISO FVPPSPEEQSISASS--SSLKCFSTLKDLDASDHEEN-VNTSKDFLSKPEKLTTQE---P CHICK10_PE561 ENSGALG00000008256 VVPPSPEEELPSFSPSVRNV---SNIFKESPTDGRS----AVHGTESEPELMAPKQPA-A CHICK10_PE562 ISOFORMIN VVPPSPEEELPSFSPSVRNV---SNIFKESPTDGRS----AVHGTESEPELMAPKQPA-A CHOHOGS_7525_PE1 NOISO CVPPSPEEGITSASS--SSLKCFXXXXXXXXXXIKKD-VSTSED-LSKPGKVTTHQ---P DANRE18_28_PE5 NOISO FIPPSPIPEEISLSVSDKEKSSSEP-----VTPANK---KES--SRSASGLPAPLD---- DASNOGS_6909_PE1 NOISO XXXXXX-XXXXXXXX--XXXXXXXMLKDPDTSGMKKDVFSTSEDLSSKPEKMATQH---P DIPORGS_6396_PE1 NOISO FVPPSPEEESISSA---TSSKCLSVLKDFDASDQEKD-------LLSKPAKIAGQE---P ECHTEGS_8292_PE1 NOISO FVPPSPEEEIISVGS--SSLKTLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---X ERIEUGS_8376_PE1 NOISO LVPRSPEEEIIS-----SSFPCISILKDLDTSEGKKD----TAEDLSKPEQTTSQQ---F GASACGROUPXIX_14_PE2 ENSGACG00000010863 YIPPSPIPDEISYTTSALETRS-KS-----VD--AK---SR-DSCVQSKGPIATLHASSD GORGO15_75_PE1 ENSGGOG00000007710 FVPPSPEEIISAS-S--SSSKCLSVLRDLDTSDRKEDVLSTSKDLLSKPEKMSMQE---L GORGO15_75_PE2 ISOFORMIN FVPPSPEEIISAS-S--SSSKCLSVLRDLDTSDRKEDVLSTSKDLLSKPEKMSMQE---L HORSE1_98_PE1 NOISO FVPPSPEEGMISGSS--SSLKCLSVLKDLDTPDRKDG-LSTSED-LSKAEKMTVQQ---P HS15_PE1548 NOISO FVPPSPEEIISAS-S--SSSKCLSTLKDLDTSDRKEDVLSTSKDLLSKPEKMSMQE---L LAMPAGS_3334_PE4 NOISO FVPPSPEEGMTSTSS--SSLKCSSVLKDLDTSDRKNG-LTQSED-LSSPEKVTTQR---P LOXAF28_17_PE12 NOISO FVPPSPEE-IISSTS--SSLKCFSMVKDLDTSDRKKDVLSTSEDLLSKPEKMTAQQ---P MACEUGS_9520_PE1 NOISO FVPPSPEEGVFSSPS--SSLMCLSTIKDPSICDGEKNSTKLSNYFSSESEKTTSP--Q-P MACMU7_73_PE3 NOISO FVPPSPEEI-SAS-S--SSSKCLSMLKDLDTSDRKEDVLSTSKDLLSKPEKMSTQE---P MONDO1_124_PE7 ENSMODG00000019449 FIPPSPEEEVFSPSSCSSSLKYFSTLKESSTCDKEKNGTKLSDDFLSESEKTTSL--Q-P MONDO1_124_PE8 ISOFORMIN FIPPSPEEEVFSPSSCSSSLN---TLKESSTCDKEKNGTKLSDDFLSESEKTTSL--Q-P MOUSE7_PE2117 NOISO FVPPSPEE-IISTAS--SSLKCSSMLKDLDDSDKEKGILSTSEELLSKPEEMTTHK---S MYOLUGS_5736_PE1 NOISO XXXXXXXXXXXXX-X--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---X OCHPRGS_2270_PE1 NOISO FVPPSPEEELSSTTS--SSLRCSSVLKDLDTSHKDG--LSISEDTLSIPQKRTPPE---P ORYLA6_13_PE34 NOISO ------------------------------------------------------------ OTOGAGS_5666_PE1 NOISO FVPPSPEEESISTAS--SSLKCFXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXX---X PANTR15_94_PE1 NOISO FVPPSPEKIISSS-S--SSSKCLSMLKDLDTSDRKEDVLSTSKDLLSKPEKMSTQE---L PIG7_61_PE11 NOISO -----------------------SMLKDLDTSDRRDG-LGTSED-LSEPEKMTSQQ---P PIG7_61_PE12 NOISO ------------------------------------------------------------ POEGU10_21_PE29 NOISO IIPPSPEEELPAFSPSVQSASVFRD----SPTGGRC----TAGSSEARQEKVSTVHPG-- PONPY15_91_PE1 NOISO FVPPSPEEIISAS-S--SSSKCLSMLKDLDTSDRKEDVLSTSKDLLSKPEKMSMQE---P PTEVAGS_3767_PE1 NOISO FVPPSPEEEMTSASS--SSLKCFSMLKDLDTCDQKKESFGTSED-LTKPEKMPTQQ---S RABITUN0040_2_PE4 ENSOCUG00000013969 FVPPSPEEEVSSATS--SSLKCSSMLKDLDTPHREKDVLSPAQDLLSKPEKLTPQE---P RAT1_PE1918 ENSRNOG00000011213 FVPPSPEE-IISTAS--SSLKCSSMLKDLDDSDKEKDILSTSKD-LSKPEEMTTPK---S RAT1_PE1919 ISOFORMIN FVPPSPEE-IISTAS--SSLKCSSMLKDLDDSDKEKDILSTSKD-LSKPEEMTTPK---S SORARGS_6804_PE1 NOISO XXXXXXXXXXXXXXX--XXXXXXXILKDLDTSEGKAGHLNMSEG-LSKLEKRTTQQ---S TARSYGS_7935_PE1 NOISO FVPPSPEEEINSTTS--SSLKCFXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---X TETNG13_PE138 NOISO FIPPSPISDEMSSALSARFVHLIQS-----ILAGPK---GQDSPPLQPHGPSVEDH---- TUPGBGS_2784_PE3 NOISO FVPPSPEEEIISTAS--PSVKRFXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX---X TURTRGS_3319_PE1 NOISO FVPPSPEEGMTSTSS--SSLKYSSVLKDLDTSDSKDG-LSISED-LSKSEKMTTKQ---P XENTR40_1_PE41 NOISO FIPPSPSDESLSSPPVLRVI---GAQRKHKV-SSVT----DVNDCENT---------A-D MATCH CONSENSUS ??PPSP??????????????????????????????????????????????????????

AILMEGL192700_1_1_PE16 NOISO DQEASTDCDARQTSLQQQLIHVMDQICKLVDTIPDDELKALDCGDELRQQRDIRRNLLAD ANOCA408_1_PE1 NOISO ------------------------------------------------------------ BOVIN21_23_PE15 NOISO NQETSTSCEARQTSLQQQLIRVMDRICKLVDAVPDDELKALDCGNELLQQRDIRRKLLAE CALJA6_18_PE38 ENSCJAG00000009803 NPETSTDCDARRISLQQQLIHVMDRICKLVDIIPADKLKLLDCGNELLQQRNIRRKLLTE CALJA6_18_PE39 ISOFORMIN NPETSTDCDARRISLQQQLIHVMDRICKLVDIIPADKLKLLDCGNELLQQRNIRRKLLTE CALJA6_18_PE41 ISOFORMIN NPETSTDCDARRISLQQQLIHVMDRICKLVDIIPADKLKLLDCGNELLQQRNIRRKLLTE CANFA3_58_PE22 NOISO NQETSTNCDARQPSLQQQLIHVMDQICKLVDTIPDDELKALTCGNALHQQRDIRRKLLAE CAVPO10_34_PE14 NOISO NPEISMDCDARPISLQQQLLLVMEHICKLVDTIPLDELKALDCGDELLQQRNRRRKLLSE CHICK10_PE561 ENSGALG00000008256 EQDSSAEHADKGLHLEQQLYSVMEDICKLVDAIPLHELTSISCAKELLQQRELRRKLLAD CHICK10_PE562 ISOFORMIN EQDSSAEHADKGLHLEQQLYSVMEDICKLVDAIPLHELTSISCAKELLQQRELRRKLLAD CHOHOGS_7525_PE1 NOISO NEETSTDCDARQLSLQQQLIHVMEDICKLVDTIPDEELKALDCGNELLQQRDIRRKLLAD DANRE18_28_PE5 NOISO ------QSAKGLKGADDALFSVMESICCLVDTIPEHELIALTCGTELLLQRAHRKRILAK DASNOGS_6909_PE1 NOISO NQETSTDCDARQLSLRQQLILVMEDICKLVDAIPAGELQALDCGNELLRQXXXXXXXXXX DIPORGS_6396_PE1 NOISO DLETSVDCDARRTRLQEQLIQVMERICRVVDTIRVDELTSLDCGDELLQLRDQRRKLLAE ECHTEGS_8292_PE1 NOISO XXXXXXXXXXKQLSVQQQLIRVMENICKFVDTIPEDKLRALDCGNELLQQRNIRKELLAD ERIEUGS_8376_PE1 NOISO TQDTSTDNNARQTSLQQQLICVMEHICNLVDAIPAGELRALGCGDELLQQRDIRRKLLAE GASACGROUPXIX_14_PE2 ENSGACG00000010863 NHSNDNTIFSCDYVTDEQLFSIMQCICSLVDSIPEHEVIGLSCGSELLLKRAQRKRILAT GORGO15_75_PE1 ENSGGOG00000007710 NPETSTDCDARQISLQQQLIHVMEHICKLIDTIPDDKLKLLDCGNELLQQRNIRRKLLTE GORGO15_75_PE2 ISOFORMIN NPETSTDCDARQISLQQQLIHVMEHICKLIDTIPDDKLKLLDCGNELLQQRNIRRKLLTE HORSE1_98_PE1 NOISO HQETSTDCDVRQISLQQQLIHVMDHICKLVDTIPDAELKALNCGNELLQQRNIRRKLLAE HS15_PE1548 NOISO NPETSTDCDARQISLQQQLIHVMEHICKLIDTIPDDKLKLLDCGNELLQQRNIRRKLLTE LAMPAGS_3334_PE4 NOISO DQETGTDCDARQISLQQQLIRVMDHICKLVDTIPDDELKALDCGNELLQQRDVRRKLLAE LOXAF28_17_PE12 NOISO NQETSTDCDAERLSLQQQLIRVMEDICKLVDTIPADELETLDCGNELLQQRNIRRRLLAD MACEUGS_9520_PE1 NOISO IQETTTKYDGKLLTLQQQLFHVMEDICSLVDTIPAYQLQGLACGNKLLQHRNLRRKLLAD MACMU7_73_PE3 NOISO NPETSTDCDARQINLQQQLIHVMDHICKLIDTIPADKLKLLDCGNELLQQRNIRRKLLTE MONDO1_124_PE7 ENSMODG00000019449 IQETSTKHDGKLLTLQQQLFHVMEDICSLVDTIPIIQLKGLDCGNKLLQHRDLRRKLLAD MONDO1_124_PE8 ISOFORMIN IQETSTKHDGKLLTLQQQLFHVMEDICSLVDTIPIIQLKGLDCGNKLLQHRDLRRKLLAD MOUSE7_PE2117 NOISO DAGTSKDCDAQQIRIQQQLIHVMEHICKLVDTVPTDELEALNCGTELLQQRNIRRKLLAE MYOLUGS_5736_PE1 NOISO XXXXXXXXXXRQISLQQQLIQVMDHICNLVDAIPDDELKALDCGNDLLQQRNIRRKLLAE OCHPRGS_2270_PE1 NOISO DPGTTTGCEAGQVHVRQQLLQVMHLICDLVDAIPTEALRALEGGSELLRQRDTRRKLLAE ORYLA6_13_PE34 NOISO ------------------------------------------------------------ OTOGAGS_5666_PE1 NOISO XXPESTDYDARQISVQQQLIHVMDHICKLIDTVPADKLKALDCGDELLLQRNVRRKLLAE PANTR15_94_PE1 NOISO NPETSTDCDARQISLQQQLIHVMEHICKLIDTIPDDKLKLLDCGNELLQQRNIRRKLLTE PIG7_61_PE11 NOISO NPETSTNCEAGQINVQQQLIRVMDHICKLLDTIPDDKLKALDCGNELLQQRDMRRKLLAE PIG7_61_PE12 NOISO ------------------------------------------------------------ POEGU10_21_PE29 NOISO -GDPSAGDAGEAVPVAPGLYRVMEAICELVDAIPLQELQALRCARALLQHRELRRKLLAN PONPY15_91_PE1 NOISO NPETSTDYDVGQISLQQQLIYVMEHICKLIDTIPDDKLKLLDCGNELLQQRNIRRKLLTE PTEVAGS_3767_PE1 NOISO NEESSTDCDAKQINLQQQLIRVMDHICNLVDTIPDNELKSLDCGNNLLQQRNIRRKLLAE RABITUN0040_2_PE4 ENSOCUG00000013969 DPETTAGCEARPSPVQRRLLQVMEHICVLVDAIPAEALRALEGGSELLRQRDTRRKLLAE RAT1_PE1918 ENSRNOG00000011213 DLGTNEDCDAQQTSLQQQLIRVMEHICKLVDTVPIDELKALTCGDKLLQQRDIRRKLLAE RAT1_PE1919 ISOFORMIN DLGTNEDCDAQQTSLQQQLIRVMEHICKLVDTVPIDELKALTCGDKLLQQRDIRRKLLAE SORARGS_6804_PE1 NOISO NQGNSTDCDMKQRSLQQQLMCVMDHICKLVDTISADELKTLNCGNELLQQRNLRRRLLAE TARSYGS_7935_PE1 NOISO XXXXXXXXXXGQKSLQQQLIQVMDRICKLVDTIPADKLIALDCGNELLQQRNIRRKLLAE TETNG13_PE138 NOISO ----EPLGSSAKAKTNEQLFSIMESICALVDSVPEHELIALSCGNELLLKRAQRKRILAT TUPGBGS_2784_PE3 NOISO XXXXXXXXXXRQLSLQQQLIDVMDHICKLVDSISADELKALDCGNELLQQRNIRRKLLAE TURTRGS_3319_PE1 NOISO NQETSTSYDARQISLQQQLIRVMDHICELVDTIPDDKLKTLDCGNKLLQQRDIRRKLLAE XENTR40_1_PE41 NOISO HLQSQCVSSSLDSKVPSHLLSVMLEICDLVDKIPISELHVLSCGMDLKKKRDMRKRLLLN MATCH CONSENSUS ?????????????????QL??VM??IC?L?D?IP???L??L?CG??LL??R??RR?LL??

AILMEGL192700_1_1_PE16 NOISO ANFNTSDAS--RLASVWRCWPDSLGSPVD-------D--------TGESCPAGSSV-QEL ANOCA408_1_PE1 NOISO ------------------------------------------------------------ BOVIN21_23_PE15 NOISO ADFDPSDAS--VLSAMWGCRPDPLESPVK-------G--------D--SCLAGNAV-KEF CALJA6_18_PE38 ENSCJAG00000009803 VDLNKSDAS--LLGPVWRCRPDSLDEPVE-----------------GDSCPTENSM-KGL CALJA6_18_PE39 ISOFORMIN VDLNKSDAS--LLGPVWRCRPDSLDEPVE-----------------GDSCPTENSM-KGL CALJA6_18_PE41 ISOFORMIN VDLNKSDAS--LLGPVWRCRPDSLDEPVE-----------------GDSCPTENSM-KGL CANFA3_58_PE22 NOISO ADFNTSDAS--VLASVWTRGPDSLGSPVE-------G--------N--SHPTGNSV-KEL CAVPO10_34_PE14 NOISO ADFARNDAN---LDSVWKHNPDILGSPVE-------D--------D--CCPAESSI-KGP CHICK10_PE561 ENSGALG00000008256 SGALNTNSV-NGP-RNWKACVQQ-DPSS--RPGTPLCS-----GPGRGVSSVGSTP-KST CHICK10_PE562 ISOFORMIN SGALNTNSV-NGP-RNWKACVQQ-DPSS--RPGTPLCS-----GPGRGVSSVGSTP-KST CHOHOGS_7525_PE1 NOISO ADFNRIDSG--VLGSVWKCSPDLFPLLIK-----------------GDSYSTQNSV-KKL DANRE18_28_PE5 NOISO GGSSRTSHS-DS----VSTPGFLNRPTFGVTPSNLTSLTPVTSGKRE-GVKTGFSFRKSI DASNOGS_6909_PE1 NOISO XXXXXXXXX--XXX--------XXXXXXX-------XXXXXXXXPKGDACPPQN---VQL DIPORGS_6396_PE1 NOISO VDFTRKDVS--LLSGVWKHRRDSLGISVG-----------------GDSCPLEGS--VEL ECHTEGS_8292_PE1 NOISO ADLNRSKAG--FLGPLWRCRPDLLDSPVE-----------------GDFCPTENSV-KEL ERIEUGS_8376_PE1 NOISO VDLGTCDAS--VPDAVWRCRPRPHGSPVE-------G--------G--LCPTGRSA-KEF GASACGROUPXIX_14_PE2 ENSGACG00000010863 GGCNSLSMQ-QPDSTVISDCSHKIRSSFSCDTSSVMSS--SGSGPSD-SKKP-PQIRR-- GORGO15_75_PE1 ENSGGOG00000007710 VDFNKSDAS--LLGSMWRCRPDSLDGPME-----------------GDSWPTGNSM-KEL GORGO15_75_PE2 ISOFORMIN VDFNKSDAS--LLGSMWRCRPDSLDGPME-----------------GDSWPTGNSM-KEL HORSE1_98_PE1 NOISO VDFNTSDAG--VLGSTWRGRPDSLGSPVE-------D--------AG-SCPTEN-S-VEF HS15_PE1548 NOISO VDFNKSDAS--LLGSLWRYRPDSLDGPME-----------------GDSCPTGNSM-KEL LAMPAGS_3334_PE4 NOISO ADFNISDAS--IFGSEWRCRPESLGNPV-----------------EGDSCPTGNSV-KAL LOXAF28_17_PE12 NOISO AGFNRSDAG--FLGSLWRCRPNLLDIPVE-------GV----AFSQGDFCPTENSV-QEL MACEUGS_9520_PE1 NOISO ANSSKNDA--SPPPLNWIYQPNSQDLSV--K---------------GKSPFTGNLVGE-F MACMU7_73_PE3 NOISO VDFNKSDAS--LLGSVWRCRPDSLDGPVE-----------------GDSCSAGNSM-KEL MONDO1_124_PE7 ENSMODG00000019449 ANSNKSAT--SPPPLNWIYQANSHDLSV--NDMTAFSSLH--SFQKGKSAFTGNLVRE-F MONDO1_124_PE8 ISOFORMIN ANSNKSAT--SPPPLNWIYQANSHDLS-------------------GKSAFTGNLVRE-F MOUSE7_PE2117 NOISO AGFNGNDVR--LLGSLWRHRPDSLDNTVQ-----------------GDSCPVGHPN-KEL MYOLUGS_5736_PE1 NOISO ADFNPSDAS--VLGSMWRCRPDALGNPME-----------------GDSCPTAS-S-DEL OCHPRGS_2270_PE1 NOISO AGFDRDEPH--LLGSLWRVGPDSLGSPVH-------S--------D--PCPSAAPA-KAL ORYLA6_13_PE34 NOISO ------------------------------------------------------------ OTOGAGS_5666_PE1 NOISO VDFNRSGTS--HLGSAWRLRPDPCGSPVE-------E-----------DSSGENFM-KEL PANTR15_94_PE1 NOISO VDFNKSDAS--LLGSMWRCRPDSLDGPMK-----------------GDSCPTGNSM-KEL PIG7_61_PE11 NOISO ADFNTCDAS--ALALLWRCRPASLGSPVA-------SVSSPSAFPNGNSCPTGNSV-KEL PIG7_61_PE12 NOISO ------------------------------------------------------------ POEGU10_21_PE29 NOISO SCHLNQNGTNTTFPRSWKSPVEQ-SPRV--CPGAGPGSVPSRSFGSDRN------SPKST PONPY15_91_PE1 NOISO VDFNKSDAS--LLGSMWRCRPDSLDGPME-----------------GDSCPTGNSM-KEL PTEVAGS_3767_PE1 NOISO ADFNPGDAG--VLGVVWRCRPDALGSLME-----------------GDFCPRGN-S-DEF RABITUN0040_2_PE4 ENSOCUG00000013969 ADFTRNGAS--LLGSLWEVGPDSLGSPVD-------G--------E--SCSVGDSV-KAP RAT1_PE1918 ENSRNOG00000011213 AGFNRNDVN--LLGSLWRHRPDSLDNTVQ-----------------CDSCPVGHPG-KEL RAT1_PE1919 ISOFORMIN AGFNRNDVN--LLGSLWRHRPDSLDNTVQ-----------------CDSCPVGHPG-KEL SORARGS_6804_PE1 NOISO ADFSPSDAT--V-CSGWQCRPGSLGSPVE-------G----------AAHPTEKYV-KEW TARSYGS_7935_PE1 NOISO ADCNTNDAS--LLGWIWRRRPDSLCSPVE-----------------GDSYPREISM-KEL TETNG13_PE138 NOISO GGCSLFRMQ-LPDSTVVNEVDSKENPRFSTD--------------------A-PGVRR-- TUPGBGS_2784_PE3 NOISO ADFTRYDAS--LLNSVWRCRPNLPGSLM-----------------EGDSCPMENSI-KVL TURTRGS_3319_PE1 NOISO ADFNTSDAS--VLGSLWRCRPDSLGSSVK-------G--------D--SCPTGNSV-KEF XENTR40_1_PE41 NOISO NSVLRSSPA-DSSTVSLTSCPSQ-NMEF--DVSAPKDS----------ENFSGSSVNKIF MATCH CONSENSUS ????????????????W???????????????????????????????????????????

AILMEGL192700_1_1_PE16 NOISO NFPHLPSHCGTTRECLLATTPGK-------TGFSATP------QNPFER----------- ANOCA408_1_PE1 NOISO ------------------------------------------------------------ BOVIN21_23_PE15 NOISO TLPHLPSNSMSTRERLLTPPLGK-------TGVLATT------KSPFER----------- CALJA6_18_PE38 ENSCJAG00000009803 NFLHLSSDSVSPGECLLTTTPGK-------TGFSATR------ENLFER----------- CALJA6_18_PE39 ISOFORMIN NFLHLSSDSVSPGECLLTTTPGK-------TGFSATR------ENLFER----------- CALJA6_18_PE41 ISOFORMIN NFLHLSSDSVSPGECLLTTTPGK-------TGFSATR------ENLFER----------- CANFA3_58_PE22 NOISO NFPHLPSHSSSTGECLLATTPGK-------TGFSGTM------KNPSER----------- CAVPO10_34_PE14 NOISO HVPHLPSNSLFSRECLLNTTPGK-------TGFSATS------STPFER----------- CHICK10_PE561 ENSGALG00000008256 NLPPVLSRTVNSSSFSTIRNQTLD---KLDTSYSSKET-------DQEVICLEPAALPSP CHICK10_PE562 ISOFORMIN NLPPVLSRTVNSSSFSTIRNQTLD---KLDTSYSSKET-------DQEVICLEPAALPSP CHOHOGS_7525_PE1 NOISO NFPYLPSNSVSSEECLLTTTPGK-------IGFSATK------KNPFER----------- DANRE18_28_PE5 NOISO ASVMSVGDESVFEDSDCIINGVETPGGTWNPNSSTKISAGRDTFNGSIQTLSKPESKTDK DASNOGS_6909_PE1 NOISO KLPHLPSVSVSARECLLTTTSEK-------TTSSATP------KNPCER----------- DIPORGS_6396_PE1 NOISO KFPYLPSNSLCIGENVLSTAPGK-------TGLSAST------KELFES----------- ECHTEGS_8292_PE1 NOISO HFPHFPSNVVSTGECLPTTTPGR-------TGFSATA------KNCFDR----------- ERIEUGS_8376_PE1 NOISO NSPHLALTPLPASESLLTITPAK-------TGFSATTT-----KTLPER----------- GASACGROUPXIX_14_PE2 ENSGACG00000010863 -------SSIISVDDGCDHSDGITST---KPSYSRKSGADHA-TNQS--ICDSPS---TH GORGO15_75_PE1 ENSGGOG00000007710 NFSHLPSNSVSPGDCLLTTTLGK-------TGFSATR------KNLFER----------- GORGO15_75_PE2 ISOFORMIN NFSHLPSNSVSPGDCLLTTTLGK-------TGFSATR------KNLFER----------- HORSE1_98_PE1 NOISO NFPHLPSNSISAGECLLTTTPGK-------TGFSATT------KNLFER----------- HS15_PE1548 NOISO NFSHLPSNSVSPGDCLLTTTLGK-------TGFSATR------KNLFER----------- LAMPAGS_3334_PE4 NOISO TLPHLPSNSISAGECLQTTTPGK-------TGFSATT------KNLFER----------- LOXAF28_17_PE12 NOISO NFPHLPSNSISTGTCLPTATPGK-------TGFLATP------KNLSER----------- MACEUGS_9520_PE1 NOISO KSLHFLSNPVSTTDC------TTP---EKSELSSARTN-------VSERI---------- MACMU7_73_PE3 NOISO NFSHLPSNSVSPGDYLLTTTLGK-------TGFSATR------ENLFER----------- MONDO1_124_PE7 ENSMODG00000019449 KSLHLPSKPVSTTDWMCSTQRTTP---DKSESSSDKRN-------DSERI---------- MONDO1_124_PE8 ISOFORMIN KSLHLPSKPVSTTDWMCSTQRTTP---DKSESSSDKRN-------DSERI---------- MOUSE7_PE2117 NOISO NSPYLLSHSPSTEECLPTTTPGK-------TGFSATP------KNLFER----------- MYOLUGS_5736_PE1 NOISO HFPPIPSNSISSGGCLL-TPPGK-------TGFSVTK------KNLFER----------- OCHPRGS_2270_PE1 NOISO YWPRFPSASVSTGKHL-TTGPGK-------MNFSAPT------KHLFER----------- ORYLA6_13_PE34 NOISO ------------------------------------------------------------ OTOGAGS_5666_PE1 NOISO AFPYLPSNPISPGEYLPTTALGK-------TGFLATT------KNHCES----------- PANTR15_94_PE1 NOISO NFSHLPSNSVSPGDCLLTTTLGK-------TGFSATR------KNLFER----------- PIG7_61_PE11 NOISO AFPHCLSNSFSSGEHLLTTTPGK-------TGFSATT------KTVFER----------- PIG7_61_PE12 NOISO ------------------------------------------------------------ POEGU10_21_PE29 NOISO NLPSV--LSVISSSFSASTNRTLGSSGASK-------------QSAEEMPCPGAAELPCP PONPY15_91_PE1 NOISO NFSHLPSNAVSLGTVTDYHXLGR-------QDL-CHR------KNLFDR----------- PTEVAGS_3767_PE1 NOISO NFPLVPSNSISTGECLVTTTPGR-------AGFSATR------KNLTEG----------- RABITUN0040_2_PE4 ENSOCUG00000013969 TFPHLPSNSLSNGKCLT-TPPGK-------TEFSAPT------KHLSEG----------- RAT1_PE1918 ENSRNOG00000011213 NSPYLPSHSLSTEECLPTTASGK-------TGFSATP------KSLSER----------- RAT1_PE1919 ISOFORMIN NSPYLPSHSLSTEECLPTTASGK-------TGFSATP------KSLSER----------- SORARGS_6804_PE1 NOISO SFPQLPSNSVSPGECLQTTTSAE-------NILPATV------KNHTKG----------- TARSYGS_7935_PE1 NOISO NSSHLSLDSVSPGECLLTTTPGK-------TGFSA-R------KDLFER----------- TETNG13_PE138 NOISO -------SSSVFADCSSEHSDSIIPA---APVSSKKSTT-AQ-ADYE--RCDSPS---AR TUPGBGS_2784_PE3 NOISO YFLHFPSNSFSSGECLLTTTLGK-------TGFSATT------KNPFES----------- TURTRGS_3319_PE1 NOISO TFPNLPSNSISTGECLLTPTPGK-------TGFSATT------KNLFER----------- XENTR40_1_PE41 NOISO KFN-----KLVADEFGTKGNDRAS---DFAPNFREKM----------------------- MATCH CONSENSUS ????????????????????????????????????????????????????????????

AILMEGL192700_1_1_PE16 NOISO -------PLFSPHLQKSFVSS--NWAETP--RIEKRNESSYFPGNVLTSTAVKDQNKRAA ANOCA408_1_PE1 NOISO ------------------------------------------------------------ BOVIN21_23_PE15 NOISO -------PLFSSHLQKSFVSS--NWAETP--RAEKRNESPDFPGNVLTSTAVKDQNKYTT CALJA6_18_PE38 ENSCJAG00000009803 -------PLFNTHLQKSFVSS--NWAETP--RLEKRNESPYFPGNVLTSTAVKDWNKHTA CALJA6_18_PE39 ISOFORMIN -------PLFNTHLQKSFVSS--NWAETP--RLEKRNESPYFPGNVLTSTAVKDWNKHTA CALJA6_18_PE41 ISOFORMIN -------PLFNTHLQKSFVSS--NWAETP--RLEKRNKNHSKS----------------- CANFA3_58_PE22 NOISO -------LLFSPHLQKSFVSS--NWAETP--RIEKRNESSYFLGNVLTSTAVRDQNKRAA CAVPO10_34_PE14 NOISO -------PLFSSHLQKSFVSS--NWAETP--RVEKRNESSYFPGNVLTSTAVKDQKKHAA CHICK10_PE561 ENSGALG00000008256 KVNGKGSTSLSRPSEASFNGS---WCEKPTGRDSGNWRVPE---RPTASTALKAQHTAPA CHICK10_PE562 ISOFORMIN KVNGKGSTSLSRPSEASFNGS---WCEKPTGRDSGNWRVPE---RPTASTALKAQHTAPA CHOHOGS_7525_PE1 NOISO -------PLFNSHLDKSFVSS--NWAETP--RIEKRNESSYFPGSVLTSTAVKDQSKHTA DANRE18_28_PE5 NOISO CYSR-----------LS---------FNESSNQTDLFYSPKRVDS---GSRNADSSVEIN DASNOGS_6909_PE1 NOISO -------PFFNSQLHKSFVSS---SAETP--RTEKRKESPYFPGNVLTSTAVKDQSKHTT DIPORGS_6396_PE1 NOISO -------PSFSSPSQKAFVSS--KWAETP--SRERRNESSYFPGKALTSTTVKDLSKHPA ECHTEGS_8292_PE1 NOISO -------PLFSSHLPKSFVSS--NCTATP--KSDERYESTCFPENVLTSTAVKDLKKYPI ERIEUGS_8376_PE1 NOISO -------PLLGSHLQKSLVSD--SWAETP--STDQRSERSYFPGKVLTSTAVKDQNKHNA GASACGROUPXIX_14_PE2 ENSGACG00000010863 RLTG-----------PSFNSS---KKSTTHADGSDRLFSPKKPET---VVQSKSNTP--- GORGO15_75_PE1 ENSGGOG00000007710 -------PLFNTHLQKSFVNS--NWAETP--RLGKKNESSYFPGNVLTSTAVKDQNKHTA GORGO15_75_PE2 ISOFORMIN -------PLFNTHLQKSFVNS--NWAETP--RLGKKNESSYFPGNVLTSTAVKDQNKHTA HORSE1_98_PE1 NOISO -------PLFNSHLQKSFVSS--NWAETP--RIEKRNESSYFPGNVLTSTAVKDQNKHTA HS15_PE1548 NOISO -------PLFNTHLQKSFVSS--NWAETP--RLGKKNESSYFPGNVLTSTAVKDQNKHTA LAMPAGS_3334_PE4 NOISO -------PLFNSHLQKSFVSS--NWAETP--RIEKRNESSYFPGNVLTSTAVKDKNKHTT LOXAF28_17_PE12 NOISO -------PLFSSQLQRSFVSS--SCAVTP--GLGQSKKNIKSE----------------- MACEUGS_9520_PE1 NOISO --------LLSSQSPEPFVRS---SSAEI-LKTEEKYKRPHLLGNILTSTAIKDQNKHIN MACMU7_73_PE3 NOISO -------PSFNTPLQKSFVSS--NWAETP--RLGKKNESSYFPGNVLTSTAVKDQNKHTA MONDO1_124_PE7 ENSMODG00000019449 --------SSSSQSPEPFISS---NSVEI-SKTEEKYKRSHLLGNFLTSTAIKDQNKHIN MONDO1_124_PE8 ISOFORMIN --------SSSSQSPEPFISS---NSVEI-SKTEEKYKRSHLLGNFLTSTAIKDQNKHIN MOUSE7_PE2117 NOISO -------PLLNSHLQKSFVSS--NWAETP--RMENRNESTDFPGSVLTSTTVKAQSKQAA MYOLUGS_5736_PE1 NOISO -------PLFNSHLQKSFVSS--NWAETP--RTEKRNESSHFPGSVLTSTAVKDQNKHTV OCHPRGS_2270_PE1 NOISO -------PSSSSHLQKSFVGSSPLWPETP--GPQ-GSEGCSFPGSMLTSTAVKEQRTHTA ORYLA6_13_PE34 NOISO ------------------------------------------------------------ OTOGAGS_5666_PE1 NOISO -------MLLESSLQKSFVSN--NWAETP--KLEKSKESSFFPGSVLTSTAVKDQNKNTA PANTR15_94_PE1 NOISO -------PLFNTHLQKSFVSS--NWAETP--RLGKKNESSYFPGNVLTSTAVKDQNKHTA PIG7_61_PE11 NOISO -------PPFNSHLQKSFVSS--NWAETP--RVEKRNESSYFPGNVLTSTAVKDQNKHT- PIG7_61_PE12 NOISO ------------------------------------------------------------ POEGU10_21_PE29 NOISO TGGGRQGASL-RLSPRSCNSS---WDPSPGARNG---------IQPLCSTALRAPSTAAT PONPY15_91_PE1 NOISO -------PLFI-PIYRSLVSS--NWAETP--RLGK-NESSYFPGNVLTSTAVKDQNKHTA PTEVAGS_3767_PE1 NOISO -------TSFISHVQQSFVSS--DHTDTP--RDRKKNKSSRFPXXXXXXXXXXXXXXXXX RABITUN0040_2_PE4 ENSOCUG00000013969 -------PSFSSHLHKSFVSG--NWADTP--RTGQRNGRCYFPENVLTSTAVRDQSKHRA RAT1_PE1918 ENSRNOG00000011213 -------PPLNSHLQKSFVSS--NWAETP--RTESRTESTYFPGSVLTSTTVKDESKHVA RAT1_PE1919 ISOFORMIN -------PPLNSHLQKSFVSS--NWAETP--RTESRTESTYFPGSVLTSTTVKDESKHVA SORARGS_6804_PE1 NOISO -------QSLNSRIQKSSVSS--NCLESP--RPEKRNESSYFPGKVLTSTAVKDQNKHAT TARSYGS_7935_PE1 NOISO -------PLFNSHLQESFVSS--NWAETP--RLQKRNESSYFPGNVLTSTAVKDQNKHTA TETNG13_PE138 NOISO TVKN-----------AHLEFS---D-AGADLGGLDLFFSPKRQET---SLKNTP------ TUPGBGS_2784_PE3 NOISO -------LLFNSHLQKSFVSN--NWAKTP--RIEKRNESSYFPGNVLTSTAVKDQNKHTA TURTRGS_3319_PE1 NOISO -------PLFNSHLQESFVSS--NWAETP--RVEKRNESSYFPGNVLTSTAVKDQNKHTT XENTR40_1_PE41 NOISO --ENKTSFSLQAGGDSVMEDS---FSFQSNVLSTSQFNTPQN-EKPVSSST----CARPI MATCH CONSENSUS ????????????????S???S???????????????????????????S???????????

AILMEGL192700_1_1_PE16 NOISO PIDDLER----ETQAACDIDNFDIDGFDDD-DDDDWENIIHDLA-ASKSSTAASQPIKEG ANOCA408_1_PE1 NOISO ------------------------------------------------------------ BOVIN21_23_PE15 NOISO SINDLER----ELQAACEIDNFDIDDFDDD--DDDWENLMQNLA-ASKSSTAAYPPIKEG CALJA6_18_PE38 ENSCJAG00000009803 SINDLER----ESQPSCDIGNFDIDDFDD---DDDWEDIMHNLA-ASKSSTAAYQPIKEG CALJA6_18_PE39 ISOFORMIN SINDLER----ESQPSCDIGNFDIDDFDD---DDDWEDIMHNLA-ASKSSTAAYQPIKEG CALJA6_18_PE41 ISOFORMIN ------------------------------------------------------------ CANFA3_58_PE22 NOISO PINDLE------IQAACDIDNFDIDGFDD---DDDWEDIMHDLA-ASRSSTAACLPIKEG CAVPO10_34_PE14 NOISO SVNNLER----ESQASPDVDNFNIDDFDD---DDDWEKIMQDLT-ANKTSTAACQPIQKG CHICK10_PE561 ENSGALG00000008256 GAPASGCW--DVNDTDFDLDHFDIDDFDEGWEDAV----APEAA-PEAPPAPQWQPLREG CHICK10_PE562 ISOFORMIN GAPASGCW--DVNDTDFDLDHFDIDDFDEGWEDAV----APEAA-PEAPPAPQWQPLREG CHOHOGS_7525_PE1 NOISO SINDLEKREVSEIQASCNIDNFNIDDFDD---DDDWENIMHNLA-ASKSSTSAYQPIKEG DANRE18_28_PE5 NOISO IAGSSSLRTGAEPVDDFLLDDFDIDDFDENDIPDYYEEPPSVLE-SRNNSGVKTPSVQEG DASNOGS_6909_PE1 NOISO SINDLERREVSEIQGSCDIDNFDIDDFDD---DDEWENIMHNLA-ASKSSTSAYQPIKEG DIPORGS_6396_PE1 NOISO SGDNLAR----EAPTSCDVDDFDIDDFDD---DDDWDNIMQNLP-ASKPSTAVYPPVREG ECHTEGS_8292_PE1 NOISO PTNGLERRDGSETQAFYHTDHFDIEDFDDD--DDEWENIMHNLT-ASKSSTAAYQPIKEG ERIEUGS_8376_PE1 NOISO SMNDSET----ELQACCDIDNFDIDGFDD---DDDWEDIMHNLT-ANKSSTAAYHPIKEG GASACGROUPXIX_14_PE2 ENSGACG00000010863 ---AASTATEDVELDDFYNDYFDIDDFNDSDVPSYFDEPSNSST-VAS-------TAKDL GORGO15_75_PE1 ENSGGOG00000007710 SINDLER----ETQPSYDIDNFDIDDFDD---DDDWEDIMHNLA-ASKSSTAAYQPIKEG GORGO15_75_PE2 ISOFORMIN SINDLER----ETQPSYDIDNFDIDDFDD---DDDWEDIMHNLA-ASKSSTAAYQPIKEG HORSE1_98_PE1 NOISO SVNDLER----EIQASREIDNFDIDDFDD---DDDWENIMHNLA-ASKSSTAAYQPVKEG HS15_PE1548 NOISO SINDLER----ETQPSYDIDNFDIDDFDD---DDDWEDIMHNLA-ASKSSTAAYQPIKEG LAMPAGS_3334_PE4 NOISO SIIDLER----EIQASYDIDNFDIDDFDDD-DDDDWENMMHNLA-ASKSSTAAYQPIKEG LOXAF28_17_PE12 NOISO ------------------------------------------------------------ MACEUGS_9520_PE1 NOISO ---LVNDLRSKNFSETQDIDIFDIDDFDDYDWENP----SYNSV-EEESSKNIYLPIREG MACMU7_73_PE3 NOISO SINDLER----ETQPSYDIDNFDIDDFDD---DDDWENIMHNLA-ASKSSTAAYQPIKEG MONDO1_124_PE7 ENSMODG00000019449 ---SVNDLRN-GFSETQDIDIFDVDDFDDSDWENP----NYNSA-EEKSSKNKYLPIREG MONDO1_124_PE8 ISOFORMIN ---SVNDLRN-GFSETQDIDIFDVDDFDDSDWENP----NYNSA-EEKSSKNKYLPIREG MOUSE7_PE2117 NOISO SGWNVER----HGQASYDIDNFNIDDFDDDDDDDDWENIMHNFP-ASKSSTATYPPIKEG MYOLUGS_5736_PE1 NOISO STDDLER----EIQASCEIDNFDIDDLDD---DDEWENIMHGLA-TNKSSTAAYPPIKEG OCHPRGS_2270_PE1 NOISO ------R----NAQATCVIDSFDIDDFDD---DDDWEDIMHSVTTANKSSTAAYPPIREG ORYLA6_13_PE34 NOISO ------------------------------------------------------------ OTOGAGS_5666_PE1 NOISO SINDLER----EIQASCEVDNFDIDDFDD---DDDWENIMHNLA-ASKSSTTAHQPIREG PANTR15_94_PE1 NOISO SINDLER----ETQPSYDIDNFDIDDFDD---DDDWEDIMHNLA-ASKSSTAAYQPIKEG PIG7_61_PE11 NOISO TINDLER----EIQASCDIDNFDIDDFDDD--DDDWENMMHNLA-ASKSSTAVYQPIKEG PIG7_61_PE12 NOISO ------------------------------------------------------------ POEGU10_21_PE29 NOISO ASPAGSSL--AADHPDLELDAFDIDDLDEDWESLL-----PAAA-AEAPATPLCPPVPRG PONPY15_91_PE1 NOISO SINDLER----ETQPSYDIDNFDIDDFDD---DDDWENIMHNLA-ASKSSTAAYQPIKEG PTEVAGS_3767_PE1 NOISO XXXXXXX----XXXXXXXXXXXXXXXXXX---XXXXXXXXXXXX-XXXXXXXXXXXXXXX RABITUN0040_2_PE4 ENSOCUG00000013969 SASDTAR----DARAACDVDDFDIDDFDD---DDDWEDIMHSLA-ANKSSTAAYRPIREG RAT1_PE1918 ENSRNOG00000011213 SGRDIER----EVQASYDIDNFNIDDFDDD-DDDDWENIMHNFS-VSKSSTAAYPPIKEG RAT1_PE1919 ISOFORMIN SGRDIER----EVQASYDIDNFNIDDFDDD-DDDDWENIMHNFS-VSKSSTAAYPPIKEG SORARGS_6804_PE1 NOISO SVTDSGR----EAKALSDMDNFEIDDFDD---DDDWEDIMHNLT-SSKTSTAAYQPIKEG TARSYGS_7935_PE1 NOISO SISDLER----ETQASYDIDNFDIDDFDD---DDDWENIMHNLA-ASKSSTAAYQPIKEG TETNG13_PE138 NOISO ----RTSASEDAERDDFYDDDFDIDDLNDYDFPSYYEEPPPSPV-TSPNPRTLDRTIREG TUPGBGS_2784_PE3 NOISO SMNDLKS----ETQASYDIDNFDIDDFDDD--DDEWENIMQNLA-ANKSSTAACQPVKEG TURTRGS_3319_PE1 NOISO SMNDLER----EIQASCDIDSFDIDDFDDD--DDDWENVMHNLA-ASKSSTAAYQPIKEG XENTR40_1_PE41 NOISO SQ-PIDDM--DNPDLDFDIDNFDIEDFDDQLMDSP----AAPPV--SSKNAPQYPTICET MATCH CONSENSUS ???????????????????D?F?IDDFD??????????????????????????????EG

AILMEGL192700_1_1_PE16 NOISO RPVKPVSERISSAKANCLPVASTAQDKN------SESVQNYTDKSAQNLASRNLKHERFQ ANOCA408_1_PE1 NOISO -------------------------------------------------SARNPSLERFR BOVIN21_23_PE15 NOISO RPVKSVSERPSSAKTDCLPGASTTQNKN-----FSESIPNYPDKMEQNLASRNPKHERFQ CALJA6_18_PE38 ENSCJAG00000009803 RPIKSVSEQLSSAKTNCLPVASTAQNKN-----FSESMQNYTDKSTQNLASRNLKHERFQ CALJA6_18_PE39 ISOFORMIN RPIKSVSEQLSSAKTNCLPVASTAQNKN-----FSESMQNYTDKSTQNLASRNLKHERFQ CALJA6_18_PE41 ISOFORMIN ------------------------------------------------------------ CANFA3_58_PE22 NOISO RPVKPVSERISSAKTNCLPVASTAQNKN------SESIQNYTDKSAQNLASRNLKHERFQ CAVPO10_34_PE14 NOISO GPLKSISEKIALAKMHSLPGASVVPHHT-----DLGNLQKTIDKLTQNLASRNTSQERFQ CHICK10_PE561 ENSGALG00000008256 SASLR-----------CRLLAAAAGSAPGPHPTAPKSGCGISAKSSSEPLVHNPAHERFR CHICK10_PE562 ISOFORMIN SASLR-----------CRLLAAAAGSAPGPHPTAPKSGCGISAKSSSEPLVHNPAHERFR CHOHOGS_7525_PE1 NOISO RPIKSVSERISSAKTNCLPVSSTAQNKN-----FSESIQNYTGKSGQNLASKNLKHECFQ DANRE18_28_PE5 NOISO GSSK-SF-----------------ERK-TFTPPAPKSI----KTPNPEPLYRNPAHDRFR DASNOGS_6909_PE1 NOISO RPIKSVSERISSAKADHLPLVSTVQNKN-----FSESIQNYTGKSRQNLASRNLKHECFQ DIPORGS_6396_PE1 NOISO GPVKSLS-----AKTHCLPAASAAQRK------SSEAVQNYADKLAQNFTSRNVKHERFQ ECHTEGS_8292_PE1 NOISO RPIKSLSQGMSSAKTNCLPGAFTAHHKN-----FSESTQNYIDKSGQNFASKSVKHERFQ ERIEUGS_8376_PE1 NOISO RPVKSVSERISSAKTNCLPVIATTQSKN-----FSESIQNYPDKSTQNLASKNLKHEHFQ GASACGROUPXIX_14_PE2 ENSGACG00000010863 RSCESPW-----------------GNKPTTPAPAPKPA----KICSPEPTYRNPAHDRFR GORGO15_75_PE1 ENSGGOG00000007710 RPIKSVSERLSSAKTNCLPVASTAQNIN-----FSESIQNYTDKSAQNLASRNLKHERFQ GORGO15_75_PE2 ISOFORMIN RPIKSVSERLSSAKTNCLPVASTAQNIN-----FSESIQNYTDKSAQNLASRNLKHERFQ HORSE1_98_PE1 NOISO GPVKSVSERISSAKTNCLPVASTAQNKN-----FSESIQNCTVKSAQNLASGNLKHERFQ HS15_PE1548 NOISO RPIKSVSERLSSAKTDCLPVSSTAQNIN-----FSESIQNYTDKSAQNLASRNLKHERFQ LAMPAGS_3334_PE4 NOISO RPVKSVSERISSAKTNCLPVASTAQNKN-----LSESIQSYTDKSEQNLASRNLKHKQFQ LOXAF28_17_PE12 NOISO ------------------------------------------------------------ MACEUGS_9520_PE1 NOISO HPTKSFSERIPLTKTNCLSVIPPNQNK-------STSIQNCP------------------ MACMU7_73_PE3 NOISO RPIKSVSERLSSAKTNCLPVASTAQNIN-----FSESIQNYTDKSAQNLASRNLKHERFQ MONDO1_124_PE7 ENSMODG00000019449 QPIKSFSERTPMTKTNCLLMASANQNR-------SISIQNCFDKSVQNRPSRNPEHEHFK MONDO1_124_PE8 ISOFORMIN QPIKSFSERTPMTKTNCLLMASANQNR-------SISIQNCFDKSVQNRPSRNPEHEHFK MOUSE7_PE2117 NOISO GPVKSLSERISSAKAKFLPVVSTAQNTN-----LSESIQNCSDKLAQNLSSKNPKHEHFQ MYOLUGS_5736_PE1 NOISO RPVKSVSERISPTKTNCLPVTPAAQNKN-----FSGSMQKCN-QSTQNLPSRNLNHEHFQ OCHPRGS_2270_PE1 NOISO GPLRTASEKLSLAKSNRLTAVTTTPCGH-----FSESIQNDAXXXXXXXXXXXXXXXXXX ORYLA6_13_PE34 NOISO ---------------------------------------------------RNPAHDRFR OTOGAGS_5666_PE1 NOISO RPVKSVSERISSAKTNCLPVASTAQNIN-----FSETIQSYTDKSEQDSTYRNVKHEHFQ PANTR15_94_PE1 NOISO RPIKSVSERLSSAKTNCLPVSSTAQNIN-----FSESIQNYTDKSAQNLASGNLKHERFQ PIG7_61_PE11 NOISO RPVKSVSERISSAKTDSLPVASTAQNKN-----FSESIHNYTDKSEQNLTSRNLKHKHFQ PIG7_61_PE12 NOISO ------------------------------------------------------------ POEGU10_21_PE29 NOISO PPAQSLL---------AKIMSRATGPAGGSSPAAPKPGLPMATKSHPDPVVHNPALERFR PONPY15_91_PE1 NOISO RPIKSVSERLSSAKTNCLPVASTAQNIN-----FSESIQNYTDKSAQNLASRNLKHERFQ PTEVAGS_3767_PE1 NOISO XXXXXXXXXXXXXXXXXXXXXXXXXXXX-----XXXXXXXXXXESAQNLPSRHLKHERFQ RABITUN0040_2_PE4 ENSOCUG00000013969 GPVRSASERISSAKTSCLPMVSTAHRRH-----ISESVQNDADKPAQSLASGNLKHERFQ RAT1_PE1918 ENSRNOG00000011213 GPVKSLSERISSAKAKFLPVASTAQNKN-----LSESIQNCSDKFAQNLSSKNPKHEHFQ RAT1_PE1919 ISOFORMIN GPVKSLSERISSAKAKFLPVASTAQNKN-----LSESIQNCSDKFAQNLSSKNPKHEHFQ SORARGS_6804_PE1 NOISO QPIKS-SERISPAKTNCLRMASTAQNKN-----FSGSIQSYTDKLAQNLTPRNSKHEHFQ TARSYGS_7935_PE1 NOISO PPIKSVTERIASAKTNCLPVASTAQNIN-----SSESIQSYTDKSAQNLASRNLKHERFQ TETNG13_PE138 NOISO GPTTSPW-----------------EKKPATPPSAPKPS----IVSSPEPTFRNPAHDRFR TUPGBGS_2784_PE3 NOISO RPIKVVSERFFSAKTNCLPVASTAQNKN-----FPESIQNYTXXXXXXXXXXXXXXXXXX TURTRGS_3319_PE1 NOISO RPVKSVSERISSSAKTDCLLASTAQNKN-----FSESIQNYTDKSEQSLASRDLKHERFQ XENTR40_1_PE41 NOISO QFDSG------------------SKEKVTRHNVGDKTNT-ELSDSLLKPQIVNPALERFK MATCH CONSENSUS ????????????????????????????????????????????????????N?????F?

AILMEGL192700_1_1_PE16 NOISO SLSFPHTKEMMKIFHKKFGLHNFRTNQLEAINAALLGEDCFILMPTG--GGKSLCYQLPA ANOCA408_1_PE1 NOISO GCSFPHSNEMMKVFHKRFGLHHFRTNQQEAINAALLGEDCFVLMPTG--GGKSLCYQLPA BOVIN21_23_PE15 NOISO SLNFPHTKEMMKIFHKKFGLHNFRTNQLEAINAALLGEDCFILMPTG--GGKSLCYQLPA CALJA6_18_PE38 ENSCJAG00000009803 GLSFPHTKEMMKIFHKKFGLHNFRTNQLEAINAALLGEDCFILMPTG--GGKSLCYQLPA CALJA6_18_PE39 ISOFORMIN GLSFPHTKEMMKIFHKKFGLHNFRTNQLEAINAALLGEDCFILMPTG--GGKSLCYQLPA CALJA6_18_PE41 ISOFORMIN ------------------------------------------------------------ CANFA3_58_PE22 NOISO SLSFPHTKEMMKIFHKKFGLHNFRTNQLEAINAALLGEDCFILMPTG--GGKSLCYQLPA CAVPO10_34_PE14 NOISO SLSFPHTKEMMKIFHKKFGLHNFRTNQLEAINATLLGEDCFILMPTG--GGKSLCYQLPA CHICK10_PE561 ENSGALG00000008256 GMKFSHSEEMLKIFHRKFGLHSFRTNQLEAINAALLGEDCFILMPTG--GGKSLCYQLPA CHICK10_PE562 ISOFORMIN GMKFSHSEEMLKIFHRKFGLHSFRTNQLEAINAALLGEDCFILMPTG--GGKSLCYQLPA CHOHOGS_7525_PE1 NOISO SLSFPHSKEMMKIFHKKFGLHNFRTNQLEAINAALLGEDCFILMPTG--GGKSLCYQLPA DANRE18_28_PE5 NOISO GFNFPHSPEMMKIFHKKFGLHQFRFNQLEAINASLLGEDTFVLMPTG--GGKSLCYQLPA DASNOGS_6909_PE1 NOISO SLNFPHTKEMMKIFHKKFGLHHFRTNQLEAINAALLGEDCFILMPTG--GGKSLCYQLPA DIPORGS_6396_PE1 NOISO SLDFPHTKEMMTIFHKKFGLHNFRTNQLEAINAALLGEDCFILMPTG--GGKSLCYQLPA ECHTEGS_8292_PE1 NOISO SVDFPHTKEMMKIFHKKFGLHHFRTNQLEAINAALLGEDCFILMPTX--XXXXXXXXXXX ERIEUGS_8376_PE1 NOISO SLSLPHTKEMMKIFHKKFGLHHFRTNQLEAINAALLGEDCFILMPTG--GGKSLCYQLPA GASACGROUPXIX_14_PE2 ENSGACG00000010863 GFNFPHSQEMMKIFHKRFGLHQFRFNQLEAINATILAEDTFVLMPTG--GGKSLCYQLPA GORGO15_75_PE1 ENSGGOG00000007710 SLSFPHTKEMMKIFHKKFGLHNFRTNQLEAINAALLGEDCFILMPTG--GGKSLCYQLPA GORGO15_75_PE2 ISOFORMIN SLSFPHTKEMMKIFHKKFGLHNFRTNQLEAINAALLGEDCFILMPTG--GGKSLCYQLPA HORSE1_98_PE1 NOISO SLSFPHTKEMMKIFHKKFGLHHFRTNQLEAINAALLGEDCFILMPTG--GGKSLCYQLPA HS15_PE1548 NOISO SLSFPHTKEMMKIFHKKFGLHNFRTNQLEAINAALLGEDCFILMPTG--GGKSLCYQLPA LAMPAGS_3334_PE4 NOISO SLNFPHTKEMMKIFHKKFGLHNFRTNQLEAINAALLGEDCFILMPTG--GGKSLCYQLPA LOXAF28_17_PE12 NOISO ------------------------------------------------------------ MACEUGS_9520_PE1 NOISO ----------------AFGLHHFPTNQPEAINAVLLGEGCFILMPPG--GGKSLCYQLPA MACMU7_73_PE3 NOISO SLSFPHTKEMMKIFHKKFGLHNFRTNQLEAINAALLGEDCFILMPTG--GGKSLCYQLPA MONDO1_124_PE7 ENSMODG00000019449 SLDFPHTKEMMKIFHKKFGLHHFRTNQLEAINAVLLGEDCFVLMPTG--GGKSLCYQLPA MONDO1_124_PE8 ISOFORMIN SLDFPHTKEMMKIFHKKFGLHHFRTNQLEAINAVLLGEDCFVLMPTG--GGKSLCYQLPA MOUSE7_PE2117 NOISO SLNFPHTKEMMKIFHKKFGLHNFRTNQLEAINAALLGEDCFILMPTG--GGKSLCYQLPA MYOLUGS_5736_PE1 NOISO RLNFPHTKEMMKIFHKKFGLHHFRTNQLEAINAALLGEDCFILMPTG--GGKSLCYQLPA OCHPRGS_2270_PE1 NOISO XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--GGKSLCYQLPA ORYLA6_13_PE34 NOISO GFNFPHSQEMMKIFHKRFGLHQFRFNQLEAINAALLGEDAFVLMPTG--GGKSLCYQLPA OTOGAGS_5666_PE1 NOISO SLNFPHTKEMLKIFHKKFGLHNFRTNQLEAINAALLGEDCFILMPTG--GGKSLCYQLPA PANTR15_94_PE1 NOISO SLSFPHTKEMMKIFHKKFGLHNFRTNQLEAINAALLGEDCFILMPTG--GGKSLCYQLPA PIG7_61_PE11 NOISO SLNFPHTKEMMKIFHKKFGLHNFRTNQLEAINAALLGEDCFILMPTG--GGKSLCYQLPA PIG7_61_PE12 NOISO ------------------------------------------------------------ POEGU10_21_PE29 NOISO GMKFPHSAEMMNIFHRKFGLHCFRTNQLEAINAALLGEDCFILMPTG--GGKSLCYQLPA PONPY15_91_PE1 NOISO SLSFPHTKEMMKIFHKKFGLHNFRTNQLEAINAALLGEDCFILMPTG--GGKSLCYQLPA PTEVAGS_3767_PE1 NOISO SLSFPHTREMMKIFHKKFGLHNFRTNQLEAINAALLGEDCFILMPTG--GGKSLCYQLPA RABITUN0040_2_PE4 ENSOCUG00000013969 SLNFPHTKDMMKIFHKKFGLHNFRTNQLEAINAALLGEDCFILMPTG--GGKSLCYQLPA RAT1_PE1918 ENSRNOG00000011213 SLNFPHTKEMMKIFRKKFGLHNFRTNQLEAINAALLGEDCFILMPTG--GGKSLCYQLPA RAT1_PE1919 ISOFORMIN SLNFPHTKEMMKIFRKKFGLHNFRTNQLEAINAALLGEDCFILMPTG--GGKSLCYQLPA SORARGS_6804_PE1 NOISO SLSLPHTKEMMKIFHKKFGLHNFRTNQLEAINAALLGEDCFILMPTG--GGKSLCYQLPA TARSYGS_7935_PE1 NOISO SLSFPHTKEMMKIFHKKFGLHNFRTNQLEAINAALLGEDCFILMPTG--GGKSLCYQLPA TETNG13_PE138 NOISO GFNFPYSQEMMKIFHKRFGLHQFRFNQLEAINATLGGEDTFVLMPTG--GGKSLCYQLPA TUPGBGS_2784_PE3 NOISO XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX--XXXXXXXXXXX TURTRGS_3319_PE1 NOISO SLNFPHTKEMMKIFHKKFGLHNFRTNQLEAINAALLGEDCFILMPTG--GGKSLCYQLPA XENTR40_1_PE41 NOISO SFNFPHSKEMMKIFHKKFGLHRFRTNQLEAINACLLGEDCFILMPTGNGGGKSLCYQLPG MATCH CONSENSUS ???FPH??EMMKIFHK?FGLH?FRTNQLEAINA?LLGEDCF?LMPTG??GGKSLCYQLPA

AILMEGL192700_1_1_PE16 NOISO CVSPGVTIVISPLRSLIVDQVQKLTSLDIPATYLTGDKTDSEATSIYLQLSKKDPIIKLL ANOCA408_1_PE1 NOISO CILVGVTIVISPLRSLIVDQVQKLTSMDIPATYLTGDKTDAEASRIYMQLSKKDPIIKLL BOVIN21_23_PE15 NOISO CVSPGVTIVISPLRSLIVDQVQKLTSLDIPATYLTGDKTDSEATSIYLQLSKKDPIIKLL CALJA6_18_PE38 ENSCJAG00000009803 CVSPGVTIVISPLRSLIVDQVQKLTSLDIPATYLTGDKTDSEATNIYLQLSKKDPIIKLL CALJA6_18_PE39 ISOFORMIN CVSPGVTIVISPLRSLIVDQVQKLTSLDIPATYLTGDKTDSEATNIYLQLSKKDPIIKLL CALJA6_18_PE41 ISOFORMIN ------------------------------------------------------------ CANFA3_58_PE22 NOISO CVSPGVTIVISPLRSLIVDQVQKLTSLDIPATYLTGDKTDSEATSIYLQLSKKDPIIKLL CAVPO10_34_PE14 NOISO CVLPGVTIVISPLRSLIVDQVQKLTSLDIPATYLTGDKTDSEAASIYLQLSKKDPIIKLL CHICK10_PE561 ENSGALG00000008256 CVSAGVTVVISPLRSLIIDQVQKLKTLDIAATYLTGDITDADASKTYMQLSKKDPIIKLL CHICK10_PE562 ISOFORMIN CVSAGVTVVISPLRSLIIDQVQKLKTLDIAATYLTGDITDADASKTYMQLSKKDPIIKLL CHOHOGS_7525_PE1 NOISO CVSPGVTIVISPLRSLIVDQVQKLTSLDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX DANRE18_28_PE5 NOISO CVSAGVTVVISPLRSLIVDQVQKLTTLDICATSLSGDKKDSEAARIYMQLSRKDPAIKLL DASNOGS_6909_PE1 NOISO CVSPGVTIVISPLRSLIVDQVQKLTSLDIPATYLTGDKTDSEATSIYLQLSKKDPIIKLL DIPORGS_6396_PE1 NOISO CVSPGVTIVISPLRSLIVDQVQKLTSLDIPATYLTGDKTDGEAASIYLQLSKKDPIIKLL ECHTEGS_8292_PE1 NOISO XXXXXXXXXXXXXXXXXXXXXXKLTSLDIPATYLTGDKTDSEATSIYLQLSKKDPIIKLL ERIEUGS_8376_PE1 NOISO CVSPGVTIVISPLRSLIVDQVQKLTSLDIPATYLTGDRTDSEATSIYLQLSKKEPIIKLL GASACGROUPXIX_14_PE2 ENSGACG00000010863 CVSPGVTVVISPLKSLIVDQVQKLTTLDIPATSLSGSKSDSEAGRIYMQLSRKDPIIKLL GORGO15_75_PE1 ENSGGOG00000007710 CVSPGVTIVISPLRSLIVDQVQKLTSLDFSFPYILKCIHPCMPARIYLFFSWLSLRNKFI GORGO15_75_PE2 ISOFORMIN CVSPGVTIVISPLRSLIVDQVQKLTSLD-------------------------------- HORSE1_98_PE1 NOISO CVSPGVTIVISPLRSLIVDQVQKLTSLDIPATYLTGDKTDSEATSIYLQLSKKDPIIKLL HS15_PE1548 NOISO CVSPGVTVVISPLRSLIVDQVQKLTSLDIPATYLTGDKTDSEATNIYLQLSKKDPIIKLL LAMPAGS_3334_PE4 NOISO CVSPGVTIVISPLRSLIVDQVQKLTSLDIPATYLTGDKTDSEATSIYLQLSKKDPIIKLL LOXAF28_17_PE12 NOISO ------------------------------------------------------------ MACEUGS_9520_PE1 NOISO CVSPGVTIVISPLRSLIIDQVQKLTSLDIPATYLTGDKTDSEAANIYLQLSKKDPIIKLL MACMU7_73_PE3 NOISO CVSPGVTIVISPLRSLIVDQVQKLTSLDIPATYLTGDKTDSEATNIYLQLSKKDPIIKLL MONDO1_124_PE7 ENSMODG00000019449 CVSPGVTIVISPLRSLIVDQVQKLTSLDIPATYLTGDKTDSEAANIYLQLSKKDPIIKLL MONDO1_124_PE8 ISOFORMIN CVSPGVTIVISPLRSLIVDQVQKLTSLDIPATYLTGDKTDSEAANIYLQLSKKDPIIKLL MOUSE7_PE2117 NOISO CVSPGVTIVISPLRSLIVDQVQKLTSFDIPATYLTGDKTDSEAANIYLQLSKKDPIIKLL MYOLUGS_5736_PE1 NOISO CVSPGVTIVISPLRSLIVDQVQKLTSLDIPATYLTGDKTDSEATSIYLQLSKKDPIIKLL OCHPRGS_2270_PE1 NOISO CVSPGVTIVISPLRSLIVDQVQKLTSLDIPATYLTGDKTDSEAASIYLQLSKKDPIIKLL ORYLA6_13_PE34 NOISO CVSPGVTVVVSPLKSLIVDQIQKLTTLDIPATSLSGDKSDSEAGRIYMQLSRKDPLIKLL OTOGAGS_5666_PE1 NOISO C-SPGVTVVISPLRSLIVDQVQKLTSLDIPATYLTGDKTDSEATSIYLQLSKKDPIIKLL PANTR15_94_PE1 NOISO CVSPGVTVVISPLRSLIVDQVQKLTSLDIPATYLTGDKTDSEATNIYLQLSKKDPIIKLL PIG7_61_PE11 NOISO CVSSGVTIVISPLRSLIVDQVQKLTSLDIPATYLTGDKTDSEATSIYLQLSKKDPIIKLL PIG7_61_PE12 NOISO ------------------------------------------------------------ POEGU10_21_PE29 NOISO CVSAGVTIVISPLRSLIIDQVQKLKTLDIAATYLTGDRTDADASKIYMQLSKKDPVIKLL PONPY15_91_PE1 NOISO CVSPGVTIVISPLRSLIVDQVQXXXXXXIPATYLTGDKTDSEATNIYLQLSKKDPIIKLL PTEVAGS_3767_PE1 NOISO CVSPGVTIVISPLRSLIVDQVQKLTSLDIPATYLTGDKTDSEATSIYLQLSKKDPIIKLL RABITUN0040_2_PE4 ENSOCUG00000013969 CISPGVTIVISPLRSLIVDQVQKLTSLDIPATYLTGDKTDSEAASIYLQLSKKDPIIKLL RAT1_PE1918 ENSRNOG00000011213 CVSPGVTIVISPLRSLIVDQVQKLTSFDIPATYLTGDKTDSEAANIYLQLSKKDPIIKLL RAT1_PE1919 ISOFORMIN CVSPGVTIVISPLRSLIVDQVQKLTSFDIPATYLTGDKTDSEAANIYLQLSKKDPIIKLL SORARGS_6804_PE1 NOISO CVSPGVTIVISPLRSLIIDQVQKLTSMDIPATYLTGDKTDSEATSIYLQLSKKDPIIKLL TARSYGS_7935_PE1 NOISO CISPGVTVVISPLRSLIVDQVQKLTSLDIPATYLTGDKTDSEAPTISLQLSKKTPIIKLL TETNG13_PE138 NOISO CVSPGVTVVISPLKSLIVDQIQKLTTLDIPATSLSGDLGDREAGRIYMQLSRKEPIVKLL TUPGBGS_2784_PE3 NOISO XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX TURTRGS_3319_PE1 NOISO CVSPGVTIVISPLRSLIIDQVQKLTSFDIPATYLTGDKTDSEATNIYLQLSKKDPIIKLL XENTR40_1_PE41 NOISO CVSPGVTIVISPLRSLIVDQVQKLTSLDIPATYLTGDKTDAEAASIYLQLSKKDPIIKLL MATCH CONSENSUS CVS?GVT?VISPLRSLI?DQVQKLT??DI?AT?L?GD??D??A??IY?QLS?K?P?IKLL

AILMEGL192700_1_1_PE16 NOISO YVTPEKVCASNRLISTLENLYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPS ANOCA408_1_PE1 NOISO YVTPEKVCSSGRLMSTLENLYQRQLLARFVIDEAHCVSQWGHDFRQDYKRLNMLRKKFAS BOVIN21_23_PE15 NOISO YVTPEKVCASNRLISTLENLYERKLLARFVIDEAHCVSQWGHDFRPDYKRMNILRQKFPS CALJA6_18_PE38 ENSCJAG00000009803 YVTPEKICASNRLISTLENLYERRLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPS CALJA6_18_PE39 ISOFORMIN YVTPEKICASNRLISTLENLYERRLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPS CALJA6_18_PE41 ISOFORMIN ------------------------------------------------------------ CANFA3_58_PE22 NOISO YVTPEKVCASNRLLSTLENLYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPS CAVPO10_34_PE14 NOISO YVTPEKVCASNRLISILENLYERKLLARFVIDEAHCVSQWGHDFRPDYKRMNMLRQKFPS CHICK10_PE561 ENSGALG00000008256 YVTPEKVCASNRLLSALENLYDRKLLARFVIDEAHCVSQWGHDFRKDYKRLNMLRKKFHS CHICK10_PE562 ISOFORMIN YVTPEKVCASNRLLSALENLYDRKLLARFVIDEAHCVSQWGHDFRKDYKRLNMLRKKFHS CHOHOGS_7525_PE1 NOISO XXXXXXXXXXXXXXXXXXXXYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPS DANRE18_28_PE5 NOISO YATPEKVCASGRMISALQNLYERGLLARLVIDEAHCVSQWGHDFRPDYKRLHELRRMFPN DASNOGS_6909_PE1 NOISO YVTPEKICASNRLISTLENLYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPS DIPORGS_6396_PE1 NOISO YVTPEKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX ECHTEGS_8292_PE1 NOISO YVTPEKVCASNRLLSTLENLYQRKLLARFVIDEAHCVSQXXXXXXXXXXXXXXXXXXXXX ERIEUGS_8376_PE1 NOISO YVTPEKVCASNRLISTLENLYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPS GASACGROUPXIX_14_PE2 ENSGACG00000010863 YVTPEKVSASQKLISAMQNLYERGLLVRFVIDEAHCVSQWGHDFRPDYKRLHELRQKFPS GORGO15_75_PE1 ENSGGOG00000007710 FILFTKICASNRLISTLENLYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPS GORGO15_75_PE2 ISOFORMIN ------ICASNRLISTLENLYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPS HORSE1_98_PE1 NOISO YVTPEKVCASNRLITTLENLYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPS HS15_PE1548 NOISO YVTPEKICASNRLISTLENLYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPS LAMPAGS_3334_PE4 NOISO YVTPEKVCASNRLISTLENLYERKLLARFVIDEAHCVSQWGHDFRQDYKRMSMLRQKFPS LOXAF28_17_PE12 NOISO ------------------------------------------------------------ MACEUGS_9520_PE1 NOISO YVTPEKVCASNRLISTLENLYERKLLARFVIDEAHCVSQWGHDFRPDYKRLNMLRQKFPS MACMU7_73_PE3 NOISO YVTPEKICASNRLISTLENLYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPS MONDO1_124_PE7 ENSMODG00000019449 YVTPEKVCASNRLISTLENLYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPS MONDO1_124_PE8 ISOFORMIN YVTPEKVCASNRLISTLENLYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPS MOUSE7_PE2117 NOISO YVTPEKVCASNRLISTLENLYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPS MYOLUGS_5736_PE1 NOISO YVTPEKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX OCHPRGS_2270_PE1 NOISO YVTPEKVCASNRLISTLENLYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPS ORYLA6_13_PE34 NOISO YVTPEKVSASGRLISALQNLYERGLLARFIIDEAHCVSQWGHDFRPDFKRLHELRQKFPS OTOGAGS_5666_PE1 NOISO YVTPEKVCASNRLISTLENLYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPS PANTR15_94_PE1 NOISO YVTPEKICASNRLISTLENLYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPS PIG7_61_PE11 NOISO YVTPEKVCASNRLISTLENLYNRKLLARFVIDEAHCVSQWGHDFRPDYKRMNMLRQKFPS PIG7_61_PE12 NOISO ------------------------------------------------------------ POEGU10_21_PE29 NOISO YVTPEKVCASNRLMSTLENLYDRKLLARFVIDEAHCVSQWGHDFRQDYKRLNMLRRKFGS PONPY15_91_PE1 NOISO YVTPEKICASNRLVSTLENLYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPS PTEVAGS_3767_PE1 NOISO YVTPEKVCASNRLISTLENLYERNLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPS RABITUN0040_2_PE4 ENSOCUG00000013969 YVTPEKVCASNRLISTLENLYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPS RAT1_PE1918 ENSRNOG00000011213 YVTPEKVCASNRLISTLENLYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQRFPS RAT1_PE1919 ISOFORMIN YVTPEKVCASNRLISTLENLYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQRFPS SORARGS_6804_PE1 NOISO YVTPEKVCASNRLISTLENLYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPS TARSYGS_7935_PE1 NOISO YVTPEKVCASNRLISTLENLYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPC TETNG13_PE138 NOISO YVTPEKVSASNKLISALQNLYERGLLARFVIDEAHCVSQWGHDFRPDYKKLHELRKKFPQ TUPGBGS_2784_PE3 NOISO XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX TURTRGS_3319_PE1 NOISO YVTPEKVCASNRLISTLENLYERKLLARFVIDEAHCVSQWGHDFRPDYKRMNMLRQKFPS XENTR40_1_PE41 NOISO YVTPEKVCASTRLISTMENLYERQLLARFVIDEAHCVSQWGHDFRPDYKRLNMLRQKFQS MATCH CONSENSUS YVTPEK??AS?RL?S?L?NLY?R?LLARFVIDEAHCVSQWGHDFR?DYKR???LR??F??

AILMEGL192700_1_1_PE16 NOISO VPVMALTATANPRVQKDILTQLKILQPQVFSMSFNRHNLKYYVLPKKPKKVAFDCLEWIR ANOCA408_1_PE1 NOISO VPMMALTATANPRVQKDILNQLEMLKPQVFSMSFNRHNLKYDVLPKRPKSVALDCLQWIR BOVIN21_23_PE15 NOISO VPVMALTATANPRVQKDILTQLKILRPQVFSMSFNRHNLKYYVLPKKPKKVAFDCLEWIR CALJA6_18_PE38 ENSCJAG00000009803 VPVMALTATANPRVQKDILTQLKILRPQVFSMSFNRHNLKYYVLPKKPKKVAFDCLEWIR CALJA6_18_PE39 ISOFORMIN VPVMALTATANPRVQKDILTQLKILRPQVFSMSFNRHNLKYYVLPKKPKKVAFDCLEWIR CALJA6_18_PE41 ISOFORMIN ------------------------------------------------------------ CANFA3_58_PE22 NOISO VPVMALTATANPRVQKDILTQLKILQPQVFSMSFNRHNLKYYVLPKKPKKVAFDCLEWIR CAVPO10_34_PE14 NOISO VPVMALTATANSRVQTDILTQLKILRPQVFSMSFNRHNLKYYVLPKKPKKVAFDCLEWIR CHICK10_PE561 ENSGALG00000008256 VPMMALTATANPRVQKDIQNQLEMLKPQVFTMSFNRHNLKYDVLPKKPKKVAMDCLEWIK CHICK10_PE562 ISOFORMIN VPMMALTATANPRVQKDIQNQLEMLKPQVFTMSFNRHNLKYDVLPKKPKKVAMDCLEWIK CHOHOGS_7525_PE1 NOISO VPVMALTATANPRVQKDILTQLKILKPQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX DANRE18_28_PE5 NOISO VPIMALTATATPRVQKDILNQLAMTRPQVFTMSFNRNNLKYSVLPKKPKKVDEECIQWIK DASNOGS_6909_PE1 NOISO VPVMALTATANPRVQKDILTQLKILKPQVFSMSFNRHNLKYYVLPKKPKKVAFDCLEWIR DIPORGS_6396_PE1 NOISO XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX ECHTEGS_8292_PE1 NOISO XXXXXXXXXXXXXXXXXXXXQLKILRLQVFSMSFNRHNLKYYVLPKKPKKVAFDCLEWIR ERIEUGS_8376_PE1 NOISO VPVMALTATANPRVQKDILTQLKILTPQVFSMSFNRHNLKYYVLPKKPKKVAFDCLEWIR GASACGROUPXIX_14_PE2 ENSGACG00000010863 VPMMALTATATPRVQKDILNQLNMTRPQVFTMSFNRTNLKYAVLPKKPKKVAEDCIDWIK GORGO15_75_PE1 ENSGGOG00000007710 VPVMALTATANPRVQKDILTQLKILRPQVFSMSFNRHNLKYYVLPKKPKKVAFDCLEWIR GORGO15_75_PE2 ISOFORMIN VPVMALTATANPRVQKDILTQLKILRPQVFSMSFNRHNLKYYVLPKKPKKVAFDCLEWIR HORSE1_98_PE1 NOISO VPVMALTATANPRVQKDILTQLKILSPQVFSMSFNRHNLKYYVLPKKPKKVAFDCLEWIR HS15_PE1548 NOISO VPVMALTATANPRVQKDILTQLKILRPQVFSMSFNRHNLKYYVLPKKPKKVAFDCLEWIR LAMPAGS_3334_PE4 NOISO VPVMALTATANPRVQKDILTQLKILRPQVFSMSFNRHNLKYYVLPKKPKKVAFDCLEWIR LOXAF28_17_PE12 NOISO ------------------------------------------------------------ MACEUGS_9520_PE1 NOISO VSIMALXXXXXXXXXXXXXXXXXXXXXXXFSMSFNRHNLKYSVLPKKPKKVAFDCLEWIR MACMU7_73_PE3 NOISO VPVMALTATANPRVQKDILTQLKILRPQVFSMSFNRHNLKYYVLPKKPKKVAFDCLEWIR MONDO1_124_PE7 ENSMODG00000019449 VPMMALTATANPRVQKDILTQLKILKPQVFSMSFNRHNLKYSVLPKKPKKVAFDCLEWIR MONDO1_124_PE8 ISOFORMIN VPMMALTATANPRVQKDILTQLKILKPQVFSMSFNRHNLKYSVLPKKPKKVAFDCLEWIR MOUSE7_PE2117 NOISO VPVMALTATANPRVQKDILTQLKILRPQVFSMSFNRHNLKYYVLPKKPKKVAFDCLEWIR MYOLUGS_5736_PE1 NOISO XXXXXXXXXXXXXXXXXXXXXXXXXXXXXFTMSFNRHNLKYYVLPKKPKKVAFDCLEWIR OCHPRGS_2270_PE1 NOISO VPVMALTATANPRVQKDILTQLRIAQPQVFSMSFNRHNLKYYVLPKKPKKVAYDCLEWIR ORYLA6_13_PE34 NOISO VRMMALTATATPRVQKDILNQLNMMRPQVFTMSFNRSNLKYSVLPKKPKKVDEDCIGWIK OTOGAGS_5666_PE1 NOISO VPVMALTATANPRVQKDILTQLKILRPQVFSMSFNRHNLKYYVLPKKPKKVAFDCLEWIR PANTR15_94_PE1 NOISO VPVMALTATANPRVQKDILTQLKILRPQVFSMSFNRHNLKYYVLPKKPKKVAFDCLEWIR PIG7_61_PE11 NOISO VPVMALTATANPRVQKDILTQLKILRPQV------------------------------- PIG7_61_PE12 NOISO -----------------------------FTMSFNRHNLKYYVLPKKPKKVAFDCLEWIR POEGU10_21_PE29 NOISO VPMMALTATANPRVQKDILNQLEMLKPQVFTMSFNRHNLKYDVLPKKPKKVALDCLEWIK PONPY15_91_PE1 NOISO VPVMALTATANPRVQKDILTQLKILRPQVFSMSFNRHNLKYYVLPKKPKKVAFDCLEWIR PTEVAGS_3767_PE1 NOISO VPVMALTATANLRVQKDILTQLKILRPQVFTMSFNRHNLKYYVLPKKPKKVAFDCLEWIR RABITUN0040_2_PE4 ENSOCUG00000013969 VPVMALTATANPRVQKDILTQLKIVRPQVFSMSFNRHNLKYYVLPKKPKKVAFDCLEWIR RAT1_PE1918 ENSRNOG00000011213 VPVMALTATANPRVQKDILTQLKILRPQVFSMSFNRHNLKYYVLPKKPKKVALDCLEWIR RAT1_PE1919 ISOFORMIN VPVMALTATANPRVQKDILTQLKILRPQVFSMSFNRHNLKYYVLPKKPKKVALDCLEWIR SORARGS_6804_PE1 NOISO VPVMALTATANPRVQKDILTQLKILTPQVFSMSFNRHNLKYYVLPKKPKRIAFDCLDWIR TARSYGS_7935_PE1 NOISO VPVMALTATANPRVQKDILTQLKILSPQVFSMSFNRHNLKYYVLPKKPKKVAFDCLEWIR TETNG13_PE138 NOISO VPMMALTATATPRVQKDIHNQLNMRQPQVFTMSFNRTNLKYAVLPKKPKKVDEDCISWIK TUPGBGS_2784_PE3 NOISO XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX TURTRGS_3319_PE1 NOISO VPVMALTATANPRVQKDILTQLKILRPQVFSMSFNRHNLKYYVLPKKPKKVAFDCLEWIR XENTR40_1_PE41 NOISO VPMMALTATANPRVQKDILNQLKMTKPQIFTMSFNRDNLKYDVLPKKPKRVALDCVEWIK MATCH CONSENSUS VP?MALTATA??RVQKDI??QL????PQVF?MSFNR?NLKY?VLPKKPKKVA?DC??WI?

AILMEGL192700_1_1_PE16 NOISO KHHPHDSGIIYCLSRRECDTMADTLQKDGLAALAYHAGLSDSARDEVQHKWINQDGCQVI ANOCA408_1_PE1 NOISO KYHPYDSGIIYCLSRYECDSMASNLQKAGLSALAYHAGLPDETRDIVQQKWINQDGCQII BOVIN21_23_PE15 NOISO KHHPHDSGIIYCLSRRECDTMAETLQNDGLAALAYHAGLSDSARDEVQHKWINQDGCQVI CALJA6_18_PE38 ENSCJAG00000009803 KHYPYDSGIIYCLSRRECDTMADTLQRDGLSALAYHAGLSDSARDEIQQKWINQDGCQVI CALJA6_18_PE39 ISOFORMIN KHYPYDSGIIYCLSRRECDTMADTL-----------------------QKWINQDGCQVI CALJA6_18_PE41 ISOFORMIN ------------------------------------------------------------ CANFA3_58_PE22 NOISO KYHPHDSGIIYCLSRRECDTMADTLQKDGLAALAYHAGLSDSARDEVQHKWINQDGCQVI CAVPO10_34_PE14 NOISO KHHPYDSGIIYCLSRWECDTMADTLQKDGLAALAYHAGLSDAARDEVQHKWINQDGCQVI CHICK10_PE561 ENSGALG00000008256 KYHPHDSGIIYCLSRHECDTTAAILQKEGLAALAYHAGLTDSNRDLVQKKWVNQEGCQVI CHICK10_PE562 ISOFORMIN KYHPHDSGIIYCLSRHECDTTAAILQKEGLAALAYHAGLTDSNRDLVQKKWVNQEGCQVI CHOHOGS_7525_PE1 NOISO XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVI DANRE18_28_PE5 NOISO KYYPRDSGIVYCLSRNDCDTLADSLQRAGIAALAYHAGLSDSDREYVQNKWINQDGCQVM DASNOGS_6909_PE1 NOISO KHHPYDSGIIYCLSRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQHKWINQDGCQXX DIPORGS_6396_PE1 NOISO XXXXXDSGIIYCLSRRECDTMADTLQKDGLAALAYHAGLSDSARDEVQHKWINQDGCQVI ECHTEGS_8292_PE1 NOISO KNHPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX ERIEUGS_8376_PE1 NOISO KHHPHDSGIIYCLSRRECDTMADTLQKDGLAALAYHAGLSDAARDEVQHKWINQDGCQVI GASACGROUPXIX_14_PE2 ENSGACG00000010863 KHYPRDSGIIYCLSRNDCDAMAEGLQRAHISALSYHAGLSDGDREYVQSKWINQDGCQVI GORGO15_75_PE1 ENSGGOG00000007710 KHHPYDSGIIYCLSRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWINQDGCQVI GORGO15_75_PE2 ISOFORMIN KHHPYDSGIIYCLSRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWINQDGCQVI HORSE1_98_PE1 NOISO KHHPYDSGIIYCLSRRECDTMADTLQKDGLAALAYHAGLSDSARDAVQHKWINQDGCQVI HS15_PE1548 NOISO KHHPYDSGIIYCLSRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWINQDGCQVI LAMPAGS_3334_PE4 NOISO KHHPHDSGIIYCLSRRECDTMADTLQKDGLAALAYHAGLSDSARDEVQHKWINQDGCQVI LOXAF28_17_PE12 NOISO ------------------------------------------------------------ MACEUGS_9520_PE1 NOISO KHHPHDSGIIYCLSRRECDTVADTLQKDGLAALAYHAGLSDSARDEVQHKWINQDGCQVI MACMU7_73_PE3 NOISO KHYPYDSGIIYCLSRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWINQDGCQVI MONDO1_124_PE7 ENSMODG00000019449 KHHPHDSGIIYCLSRRECDTMADTLQKDGLAALSYHAGLSDSARDEVQHKWINQDGCQVI MONDO1_124_PE8 ISOFORMIN KHHPHDSGIIYCLSRRECDTMADTLQKDGLAALSYHAGLSDSARDEVQHKWINQDGCQVI MOUSE7_PE2117 NOISO KHHPYDSGIIYCLSRRECDTMADTLQREGLAALAYHAGLSDSARDEVQHKWINQDNCQVI MYOLUGS_5736_PE1 NOISO KHHPHDSGIIYCLSRRECDTMADTLQRNGLPALAYHAGLSDSARDEVQHKWINQDGCQVI OCHPRGS_2270_PE1 NOISO KHHQYDSGIIYCLSRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQHKWINQDGCQVI ORYLA6_13_PE34 NOISO KHYPRDSGIVYCLSRNDCDAMAESLKRAGIQALSYHAGLSDGDREYVQSKWINQDGCQVI OTOGAGS_5666_PE1 NOISO KYHPYDSGIIYCLSRRECDTMAGTLRKDGLAALAYHAGLSDSERDEVQHKWINQDGCQVI PANTR15_94_PE1 NOISO KHHPYDSGIIYCLSRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWINQDGCQVI PIG7_61_PE11 NOISO ------------------------------------------------------------ PIG7_61_PE12 NOISO KHHPHDSGIIYCLSRRECDTMADTLQKDGLAALAYHAGLSDSARDEVQHKWINQDGCQVI POEGU10_21_PE29 NOISO KYHPHDSGIIYCLSRHECDTTAAILQKEGLAALAYHAGLTDSNRDLVQQKWVNQEGCQVI PONPY15_91_PE1 NOISO KHHPYDSGIIYCLSRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWINQDDCQVI PTEVAGS_3767_PE1 NOISO KHHPHDSGIIYCLSRRECDTMADTLQKNGLAALAYHAGLSDSARDEVQHKWINQDGCQXX RABITUN0040_2_PE4 ENSOCUG00000013969 KHHPYDSGIIYCLSRRECDTMADTLQKDGLAALAYHAGLSDSARDEVQHKWINQDGCQVI RAT1_PE1918 ENSRNOG00000011213 KHHPYDSGIIYCLSRKECDTMADTLQREGLAALAYHAGLSDSARDEVQHKWINQDNCQVI RAT1_PE1919 ISOFORMIN KHHPYDSGIIYCLSRKECDTMADTLQREGLAALAYHAGLSDSARDEVQHKWINQDNCQVI SORARGS_6804_PE1 NOISO KHHPYNSGIIYCLSRRECDTVADTLQRDGLAALAYHAGLSDSARDEVQHKWVNQDGCQVI TARSYGS_7935_PE1 NOISO KHHPYDSGIIYCLSRRECDTMADTLQKGSLAALAYHAGLTDSARDEVQHKWINQDGCQVI TETNG13_PE138 NOISO KHYPRDSGIIYCLSRNDCDTMAESLQRAGLLALSYHAGLRDGEREYVQTKWINQDGCQVI TUPGBGS_2784_PE3 NOISO XXXXXDSGIIYCLSRHECDTMADTLRKDGLAALAYHAGLSDSSRDEVQHKWINQDGCQVI TURTRGS_3319_PE1 NOISO KHHPHDSGIIYCLSRRECDTVADTLQKDGLAALAYHAGLSDSARDEVQHKWINQDGCQVI XENTR40_1_PE41 NOISO KYHPNDSGIIYCLSRHECDTMADTLQKGGLAALAYHAGLADSNRDYVQHKWINQDDCQVI MATCH CONSENSUS K??P?DSGIIYCLSR?ECDT?A??LQ??GL?AL?YHAGL?D??R??VQ?KWINQD?CQVI

AILMEGL192700_1_1_PE16 NOISO CATIAFGMGIDKPDVRFVIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRLKR ANOCA408_1_PE1 NOISO CATIAFGMGIDKPDVRFVIHASLPKSIEGYYQESGRAGRDGERSHCLLFYSYSDVTRLRR BOVIN21_23_PE15 NOISO CATIAFGMGIDKPDVRFVIHASLPKSVEGYYQESGRAGRDGEISHCILFYTYHDVTRLKR CALJA6_18_PE38 ENSCJAG00000009803 CATIAFGMGIDKPDVRFVIHASLPKSMEGYYQESGRAGRDGEISHCLLFYTYHDVTRLKR CALJA6_18_PE39 ISOFORMIN CATIAFGMGIDKPDVRFVIHASLPKSMEGYYQESGRAGRDGEISHCLLFYTYHDVTRLKR CALJA6_18_PE41 ISOFORMIN ------------------------------------------------------------ CANFA3_58_PE22 NOISO CATIAFGMGIDKPDVRFVIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRLKR CAVPO10_34_PE14 NOISO CATIAFGMGIDKPDVRFVIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRLKR CHICK10_PE561 ENSGALG00000008256 CATIAFGMGIDKPDVRYVIHASLPKSIEGYYQESGRAGRDGEMSHCLLFYSYSDVTRLRR CHICK10_PE562 ISOFORMIN CATIAFGMGIDKPDVRYVIHASLPKSIEGYYQESGRAGRDGEMSHCLLFYSYSDVTRLRR CHOHOGS_7525_PE1 NOISO CATVAFGMGIDKPDVRFVIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRLKR DANRE18_28_PE5 NOISO CATIAFGMGIDKPDVRYVIHASLPKSVEGYYQESGRAGRDGEISHCVLFYSYSDVIRIKR DASNOGS_6909_PE1 NOISO XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX DIPORGS_6396_PE1 NOISO CATIAFGMGIDKL-VRFVIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRLKR ECHTEGS_8292_PE1 NOISO XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLKR ERIEUGS_8376_PE1 NOISO CATIAFGMGIDKPDVRFVIHASLPKSVEGYYQESGRAGRDGEMSHCLLFYTYHDVTRLKR GASACGROUPXIX_14_PE2 ENSGACG00000010863 CATIAFGMGIDKPDVRYVIHASLPKSVEGYYQESGRAGRDGEISHCILFYSYTDVHRIKR GORGO15_75_PE1 ENSGGOG00000007710 CATIAFGMGIDKPDVRFVIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRLKR GORGO15_75_PE2 ISOFORMIN CATIAFGMGIDKPDVRFVIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRLKR HORSE1_98_PE1 NOISO CATIAFGMGIDKPDVRFVIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRLKR HS15_PE1548 NOISO CATIAFGMGIDKPDVRFVIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRLKR LAMPAGS_3334_PE4 NOISO CATVAFGMGIDKPDVRFVIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRLKR LOXAF28_17_PE12 NOISO ------------------------------------------------------------ MACEUGS_9520_PE1 NOISO CATIAFGMGIDKPDVRYVIHSSLPKSVKGYYQESGRAGRDGEMSHCLLFYSYHDVTRXXX MACMU7_73_PE3 NOISO CATIAFGMGIDKPDVRFVIHASLPKSMEGYYQESGRAGRDGEISHCLLFYTYHDVTRLKR MONDO1_124_PE7 ENSMODG00000019449 CATIAFGMGIDKPDVRYVIHSSLPKSVEGYYQESGRAGRDGEMSHCLLFYNYHDVTRLKR MONDO1_124_PE8 ISOFORMIN CATIAFGMGIDKPDVRYVIHSSLPKSVEGYYQESGRAGRDGEMSHCLLFYNYHDVTRLKR MOUSE7_PE2117 NOISO CATIAFGMGIDKPDVRFVIHASLPKSMEGYYQESGRAGRDGEISHCVLFYTYHDVTRLKR MYOLUGS_5736_PE1 NOISO CATIAFGMGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX OCHPRGS_2270_PE1 NOISO CATIAFGMGIDKPDVRFVIHASLPKSVEGYYQESGRAGRDGEISHCVLFYTYHDVTRLKR ORYLA6_13_PE34 NOISO CATIAFGMGIDKPDVRYVIHASLPKSVEGYYQESGRAGRDGEISHCILFYSYTDVHRIKR OTOGAGS_5666_PE1 NOISO CATVAFGMGIDKPDVRFVIHASLPKSVEGYYQESGRAGRDGEMSHCLLFYTYHDVTRLKR PANTR15_94_PE1 NOISO CATIAFGMGIDKPDVRFVIHASLPKSMEGYYQESGRAGRDGEISHCLLFYTYHDVTRLKR PIG7_61_PE11 NOISO ------------------------------------------------------------ PIG7_61_PE12 NOISO CATIAFGMGIDKPDVRFVIHASLPKSVEGYYQESGRAGRDGEISQCLLFYTYHDVTRLKR POEGU10_21_PE29 NOISO CATIAFGMGIDKPDVRYVIHASLPKSIEGYYQESGRAGRDGEMSHCLLFYSYSDVTRLRR PONPY15_91_PE1 NOISO CATIAFGMGIDKPDVRFVIHASLPKSMEGYYQESGRAGRDGEMSHCLLFYTYHDVTRLKR PTEVAGS_3767_PE1 NOISO XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX RABITUN0040_2_PE4 ENSOCUG00000013969 CATIAFGMGIDKPDVRFVIHASLPKSVEGYYQESGRAGRDGEISHCVLFYTYHDVTRLKR RAT1_PE1918 ENSRNOG00000011213 CATIAFGMGIDKPDVRFVVHASLPKSVEGYYQESGRAGRDGEISHCVLFYTYHDVTRLKR RAT1_PE1919 ISOFORMIN CATIAFGMGIDKPDVRFVVHASLPKSVEGYYQESGRAGRDGEISHCVLFYTYHDVTRLKR SORARGS_6804_PE1 NOISO CATVAFGMGIDKPDVRFVIHASLPKSVEGYYQESGRAGRDGEISDCLLFYTYHDVTRXXX TARSYGS_7935_PE1 NOISO CATIAFGMGIDKPDVRFVIHASLPKSVEGYYQESGRAGRDGELSHCLLFYTYHDATRLKR TETNG13_PE138 NOISO CATIAFGMGIDKPDVRYVIHASLPKSVEGYYQESGRAGRDGEISQCILFYSYTDVHRIKR TUPGBGS_2784_PE3 NOISO CATIAFGMGIDKPDVRFVIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRLKR TURTRGS_3319_PE1 NOISO CATIAF