Alignment of the gene Family HOG000111320 of HOGENOM

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Threshold: 50% 80% 100%
Size: Bigger Smaller Normal
Isoforms are ON
AILMEGL192369_1_4_PE9 NOISO ----------------MELGKGRLLRTGLNALYQAVHPVHGLVWTDGHQVVLTDLQLHSG ANOCA3_9_PE3 NOISO ----------------MELGKGKLLRTGLNALYQAIHPVHGIAWTDGKQVILTSLYLHNG ANOCA3_9_PE4 NOISO ----------------MELGKAKLLRSGLNALYQAIHPMHGIAWTDGKQVALTALHYHNK BOVIN11_80_PE9 NOISO ----------------MELGQGKLLRTGLNALYQAIHPIHGLAWTDGTQVVLTNLQLHSG CALJA14_89_PE17 NOISO ----------------MELGKGRLLRTGLNALHQALHPIHGLAWTDGNQVVLTDLQLHNG CANFA17_22_PE8 ENSCAFG00000003949 ----------------MELGEGRLLRTGMNALYQAVHPVHGLVWTDGNQVVLTDLQLHSG CANFA17_22_PE9 ISOFORMIN ----------------MELGEGRLLRTGMNALYQAVHPVHGLVWTDGNQVVLTDLQLHSG CAVPO18_7_PE5 NOISO ----------------MELGKGRLLRTRLNALRGALHPTHGLAWTDGTQVVLTELQLHSG CHICK3_PE1462 NOISO ----------------MELGKAKLLRTGLNALHQAIHPVHGIAWTDGKQVILTSLHLHNG CHICK3_PE1463 ENSGALG00000016499 NEFHGFSSLTDREPKNMELGKAKLLRTGLNALYQAIHPVHGIAWTDGKQVILTALYYHNG CHICK3_PE1464 ISOFORMIN ----------------MELGKAKLLRTGLNALYQAIHPVHGIAWTDGKQVILTALYYHNG DANRE20_47_PE11 NOISO MTKNTVFLSIGETDPSMELGKAKLLRTGLNTLHQAIHPVHGIAWTDGKQVCLTSLFSVEG DASNOGS_5924_PE3 NOISO ----------------MELGEGHLLRTGRDALYQAVHPVHGLAWTDGSQVVLTDWQLHSG DIPOR7709_PE1 NOISO ----------------MELGKGNLLRTGLNILNQAIHPSHGLAWTDGSQVVLTDLKLHSG ECHTE81750_PE1 NOISO ----------------MELGKGRLLRTGLNALYQAIHPTHGLAWTDGSHVVLTDVQLHHG FELCAGS_4949_PE2 NOISO ---------------------------GLNALYQAVHPFNGLVWTNGNQV-VTDLQHHSG FUGRU16_1_PE12 ENSTRUG00000004936 -MAIDTFNLKIEIPPKMDLGKAKLLRTGLNSLHQAIHPVHGIAWTDGKQVCLTTLYFING FUGRU16_1_PE13 ISOFORMIN ----------------MDLGKAKLLRTGLNSLHQAIHPVHGIAWTDGKQVCLTTLYFING FUGRU16_1_PE14 ISOFORMIN ----------------MDLGKAKLLRTGLNSLHQAIHPVHGIAWTDGKQVCLTTLYFING FUGRU16_1_PE15 ISOFORMIN ----------------MDLGKAKLLRTGLNSLHQAIHPVHGIAWTDGKQVCLTTLYFING GASACGROUPXVIII_14_PE60 ENSGACG00000012380 -----LSETSVLTPARMDLGKAKLLRSGLNALHRATHPVHGIAWTDGKQVCLTSLFFVNG GASACGROUPXVIII_14_PE61 ISOFORMIN ----------------MDLGKAKLLRSGLNALHRATHPVHGIAWTDGKQVCLTSLFFVNG GORGO2A_26_PE6 NOISO ----------------MELGKGKLLRTGLNALHQAVHPIHGLAWTDGNQVVLTDLRLHSG HORSE15_74_PE14 NOISO ----------------MELGKGKLLRTGLNALHQAVHPVHGLAWTDGDQIILTDIQLHAG HS2_PE405 ENSG00000163026 ----------------MELGKGKLLRTGLNALHQAVHPIHGLAWTDGNQVVLTDLRLHSG HS2_PE406 ISOFORMIN ----------------MELGKGKLLRTGLNALHQAVHPIHGLAWTDGNQVVLTDLRLHSG LAMPAGS_1066_1_PE3 NOISO ----------------MELGKGRLLRTGLNALYQAIHPIHGLAWTDGNQVVLTDLQVQSG LOXAF20_38_PE7 NOISO ----------------MELGKGKLLRTGLNALYQAVHPVHGLAWTDGTQVVLTDLQLHSG MACEUSCAFFOLD41370_PE1 NOISO ----------------MDLGKGKLLRTGLNALYQAIHPVHGIAWTDGKQVVLTALHLQNT MACMU13_24_PE8 ISOFORMIN ----------------MELGKGKLLRTGLNALHQAVHLIHGLAWTDGNQVVLTNLQLHNG MACMU13_24_PE9 ENSMMUG00000012340 ----------------MELGKGKLLRTGLNALHQAVHLIHGLAWTDGNQVVLTNLQLHNG MICMUGS_3671_1_PE4 NOISO ----------------MELGKGKLLRTGLNALYQAIHPIHGLAWTDGSQVFLTDLQLHNG MONDO1_764_PE8 ENSMODG00000009400 ----------------MDLGKGKLLRTGLNALHQAIHPIHGIAWTDGKQVVLTALQLQNK MONDO1_764_PE9 ISOFORMIN ----------------MDLGKGKLLRTGLNALHQAIHPIHGIAWTDGKQVVLTALQLQNK MONDOUN_31_PE18 NOISO ----------------MDLGKGKLLRTGINALQQAIHPIHGIAWTDGKQVVLTALQLQNK MONDOUN_32_PE1 ENSMODG00000002152 ----------------MDLGKGKLLRTGLNALQQAIHPIHGIAWTDGKQVVLTALQLQNK MONDOUN_32_PE2 ISOFORMIN ----------------MDLGKGKLLRTGLNALQQAIHPIHGIAWTDGKQVVLTALQLQNK MOUSE12_PE46 ISOFORMIN ----------------MELGNGKLPRTGLNSLNQAVHPTWGLAWTDGNRVVLTDLQLHSG MOUSE12_PE47 ENSMUSG00000051721 ----------------MELGNGKLPRTGLNSLNQAVHPTWGLAWTDGNRVVLTDLQLHSG MYOLUGS_4810_PE3 NOISO --------------------------------------------TDGKQVVLTDVQLQSG ORNAN2_7_PE6 NOISO ----------------MELGKGKLLRTGINALTEAVHPIYGLAWTDGKQVLLMP--LQNG ORYLA24_3_PE7 NOISO ------------TPAGMDLGKAKLLRTGLNTLHQAIHPVHGIAWTDGKQVCLTALYFVNG OTOGA4515_PE3 NOISO ----------------MELGKGNLLRTGLNALYQAIHPIHGLAWTDGNQVVLTDLQLHDG PANTR2A_26_PE5 ENSPTRG00000011707 ----------------MELGKGKLLRTGLNALHQAVHPIHGLAWTDGNQVVLTDLRLHSG PANTR2A_26_PE6 ISOFORMIN ----------------MELGKGKLLRTGLNALHQAVHPIHGLAWTDGNQVVLTDLRLHSG PIG3_109_PE13 NOISO ----------------MELGKGKLLRTGLNALYQAVHPIHGLAWTDGNQIVLTDLYLHRG POEGU3_109_PE6 NOISO ----------------MELGKAKLLRTGLNALHQAIHPVHGLAWTDGKQVILTALLLQSG POEGU3_110_PE1 NOISO ---------------KMDLGKAKLLRTGLNALYQAIHPVHGIAWTDGKQVILTTLYYQNG PONPY2A_91_PE8 NOISO ----------------MELGKGRLLRTGLNALHQAVHPIHGLAWTDGNQVVLTDLQLHSG PTEVAGS_3150_PE3 NOISO ----------------MELGKGKLLRTGLNALYQAIHPIHGLAWTNGNQVVLTNVQLQSG RABIT2_177_PE8 NOISO ---------------MVELGKGKLLRTGLNALHQAIHPTHGLAWTDGNQVVLTDCCLHSG SORARGS_7136_PE2 NOISO ------------------------------------------------------------ SPETRGS_4731_PE4 NOISO ----------------MELGKGKLLRTGLNVLYQAIHPNHGLAWTDGNQVFLTDLQLHNG TARSY37049_PE1 NOISO ----------------MELGKGKLLRTGLNVLDQAIHPVHGLAWTDGNHVVLTDLQLHSG TETNG14_PE545 NOISO ---SFSFLKNVSRSPEMDLGKAKLLRTGLNTLHQAIHPVHGIAWTDGKQVCLTTLFFING TUPGBGS_4558_PE2 NOISO ----------------MELGKGKLLRTGLNILYQAIHPTHGLAWTDGSQVVLTDLQLHSG TURTRGS_2798_PE3 NOISO ----------------MELGRGKLLRTGLNALYQAIHPIHGLAWTDGNQVVLTDLHLHGG XENTR180_2_PE1 NOISO ----------------MELGKGKLLRSGLNALYQAIHPVHGLAWTDGRQVVLTALHHNNE MATCH CONSENSUS ????????????????M?LGK??LLRTGLN?L?QA?HP?HG?AWTDG?QV?LT?L????G

AILMEGL192369_1_4_PE9 NOISO EARFGDSKVIGQFEHVHGVSWAPPGVADMPTLLAVQHKNHATVWQLCPSTTETGKWLMSQ ANOCA3_9_PE3 NOISO EPQFGNSNVVGQFEHVHGLHWGPSCASDLPALLAIQHKKHITMWQLCYSVSERNKLMVYQ ANOCA3_9_PE4 NOISO ELKFGESTVIGQFEHVHGLYWSPHHSANTPALLAVQHKKHVSVWQLSHSATEKNKLMVSQ BOVIN11_80_PE9 NOISO EAKFGDSTVLGQFEHVYGVSWAPPGAADTPTLLAVQHKKCVIVWQLCPSPAETSKWLMSQ CALJA14_89_PE17 NOISO EVKFGDSKVIGQFECVCGLSWAPPVAADTPVLLCVQHEKHVTVWQLCPSPMETNKWVMSQ CANFA17_22_PE8 ENSCAFG00000003949 EARFGDSKVIGQFEHVYGVSWAPPGVADMAALLAVQHKNHVIVWQLCPSTTETIKWVMSW CANFA17_22_PE9 ISOFORMIN EARFGDSKVIGQFEHVYGVSWAPPGVADMAALLAVQHKNHVIVWQLCPSTTETIKWVMSW CAVPO18_7_PE5 NOISO EVKLGDSTVLGQFEHVRGVSWAPLDAAGLPALLAVQGKTHVTVWQLGPTPTGSGKWLMSQ CHICK3_PE1462 NOISO EPKFGDSSVVGQFEHVHGLYWGP-GPPDAPALLAVQHKKHITVWQLCFNAADRNKLLVSQ CHICK3_PE1463 ENSGALG00000016499 ELKFGDSSVVGQFEHVHGLYWGPCCSTETPALLAVQHKKHVSVWRLGHSTTEKNKPLISQ CHICK3_PE1464 ISOFORMIN ELKFGDSSVVGQFEHVHGLYWGPCCSTETPALLAVQHKKHVSVWRLGHSTTEKNKPLISQ DANRE20_47_PE11 NOISO EPKFGDTNVIGQFEHVLGLFWGPLCCSGSPALLAVQHKKHVTVWQLQLSALEQNKLLCTQ DASNOGS_5924_PE3 NOISO EAKFGDSKVVGQFEHVCGLSWAPPGTADMPALLAVQHKKHVTVWQLCPITTESSWWPMTQ DIPOR7709_PE1 NOISO EARFGESKVLGQFEQVCGLSWAPPGLADVPSLLAVQHKKCVTVWQLGVSTTGANQWPMSQ ECHTE81750_PE1 NOISO EVKFGPSKVIGQFEHIYGLSWAPPATADTRALLAVQHKKHITVWQVWPSTAERSRWLMSQ FELCAGS_4949_PE2 NOISO EARFGDSEVIGQIEHVYGVSWAPPGTADMPALLAVQHKKRVIVWQLCPSSTGTNKRLMSQ FUGRU16_1_PE12 ENSTRUG00000004936 EVKFGDTNVIGQFEHVFGLFWGPLCCSDSPALLAVQHKKHVTVWQLQLSALEQNKLLCTQ FUGRU16_1_PE13 ISOFORMIN EVKFGDTNVIGQFEHVFGLFWGPLCCSDSPALLAVQHKKHVTVWQLQLSALEQNKLLCTQ FUGRU16_1_PE14 ISOFORMIN EVKFGDTNVIGQFEHVFGLFWGPLCCSDSPALLAVQHKKHVTVWQLQLSALEQNKLLCTQ FUGRU16_1_PE15 ISOFORMIN EVKFGDTNVIGQFEHVFGLFWGPLCCSDSPALLAVQHKKHVTVWQLQLSALEQNKLLCTQ GASACGROUPXVIII_14_PE60 ENSGACG00000012380 EVTFGDTNVIGQFEHVLGLSWGPLCCSDSPALLAVQHKKHVTVWQLQLSALEQNKLLCTQ GASACGROUPXVIII_14_PE61 ISOFORMIN EVTFGDTNVIGQFEHVLGLSWGPLCCSDSPALLAVQHKKHVTVWQLQLSALEQNKLLCTQ GORGO2A_26_PE6 NOISO EVKFGDSKVIGQFECVCGLSWAPPVADDTPVLLAVQHEKHVTVWQLCPSPMESSKWLTSQ HORSE15_74_PE14 NOISO EAKFGDSKVIGQFEHVYGVSWAPPSTADMPALLAVQHKKHVIVWQLCPSITETSKWPMSP HS2_PE405 ENSG00000163026 EVKFGDSKVIGQFECVCGLSWAPPVADDTPVLLAVQHEKHVTVWQLCPSPMESSKWLTSQ HS2_PE406 ISOFORMIN EVKFGDSKVIGQFECVCGLSWAPPVADDTPVLLAVQHEKHVTVWQLCPSPMESSKWLTSQ LAMPAGS_1066_1_PE3 NOISO EATFGDSKVIGQFEHVYGVSWAPPGTADTPALLAVQHKMHVIVWQLCPSTSDTGKWLMSQ LOXAF20_38_PE7 NOISO EAKFRDSKVIGQFEHVYGLSWAPPGTAEEPTLLAVQHKKHVTVWQLCPSTTETNEQVMSQ MACEUSCAFFOLD41370_PE1 NOISO EPKFGDSRIMGQFEHVHGLSWGPSGVTGSPTLLAVQHKKHVTVWQLCFSLSYRSRLLVSQ MACMU13_24_PE8 ISOFORMIN EVKFGDSKVIGQFECVCGLSWAPPVADDTPVLLAVQQEKRVTVWQLCPSPTESSRWLTSQ MACMU13_24_PE9 ENSMMUG00000012340 EVKFGDSKVIGQFECVCGLSWAPPVADDTPVLLAVQQEKRVTVWQLCPSPTESSRWLTSQ MICMUGS_3671_1_PE4 NOISO EAKFGNSKVIGQFEHVCGLSWAPAGPTDIPALLAVRHEKHVTVWLLCPSTMETSKWLMSQ MONDO1_764_PE8 ENSMODG00000009400 EPTFGDSRIIGQFEHVYGLSWGPVGSEGTPTLLAIQHKKHVTVWQVCSSPLERGKLLVSQ MONDO1_764_PE9 ISOFORMIN EPTFGDSRIIGQFEHVYGLSWGPVGSEGTPTLLAIQHKKHVTVWQVCSSPLERGKLLVSQ MONDOUN_31_PE18 NOISO EPKFGDSKIIGQFEHVYGLSWSPMGSEGTPTLLAVQHKKHVTVWQVCLSSSERGKVLVSQ MONDOUN_32_PE1 ENSMODG00000002152 EPKFGDSKIIGQFEHVYGLSWSPMGSEGTPTLLAVQHKKHVTVWQVCLSSSERGKLLVSQ MONDOUN_32_PE2 ISOFORMIN EPKFGDSKIIGQFEHVYGLSWSPMGSEGTPTLLAVQHKKHVTVWQVCLSSSERGKLLVSQ MOUSE12_PE46 ISOFORMIN EAKFGDSRVIGRFESVCGVCWAPVRTVRSPALLAIQHRKLVSVWQLCPSTAGASKWQASQ MOUSE12_PE47 ENSMUSG00000051721 EAKFGDSRVIGRFESVCGVCWAPVRTVRSPALLAIQHRKLVSVWQLCPSTAGASKWQASQ MYOLUGS_4810_PE3 NOISO EPKFGDSKVIGQFEHVYGVSWAPPGIADTPPLLAVQHKQHVTVWQLCPSATETSKPLLSQ ORNAN2_7_PE6 NOISO EPGLSGSSVIGQFEHVHGLSWCPVFQANWPALLAVQHKKHVTVWELCYSSPEKNKLLVSQ ORYLA24_3_PE7 NOISO EVKFGDTNVIGQFEHVFGLFWGPLCCSDSPALLAVQHKKHITVWQLQLSALEQNKLLCTQ OTOGA4515_PE3 NOISO EAKFGDSIVIERFEYVCGLSWAPADTVDKHSLLAVQHKKCVTVWVLGPRTMETSKWLMSQ PANTR2A_26_PE5 ENSPTRG00000011707 EVKFGDSKVIGQFECVCGLSWAPPVADDTPVLLAVQHEKHVTVWQLCPSPMESSKWLTSQ PANTR2A_26_PE6 ISOFORMIN EVKFGDSKVIGQFECVCGLSWAPPVADDTPVLLAVQHEKHVTVWQLCPSPMESSKWLTSQ PIG3_109_PE13 NOISO EAMFGDSTVIGQLDHVCGVSWAPPRTADTLALLAVQHNKHVTVWQLCPRTSETSKWFMSQ POEGU3_109_PE6 NOISO EPQFGDSSVVGQFEHVHGLYWGP-CPAEAPALLAVQHKKHITIWQLCFNGADRNKLLVSQ POEGU3_110_PE1 NOISO ELKFGDSSILGQFEHVHGLSWGPYCSTDTPALLAVQHKKHVSIWQLVYSSAEKKKPLISQ PONPY2A_91_PE8 NOISO EVKFGDSKVIGQFECVCGLSWAPPVADDIPVLLAVQHEKHVTVWQLCPSPTESSKWPTSQ PTEVAGS_3150_PE3 NOISO EAKFGDSKVIGHFEHVYGVSWAPPGSADRPALLAVQHKQHVTVWQLCLSTTETSTWLMSQ RABIT2_177_PE8 NOISO EVKVGGSKVIGR-EHVCGLCWAPCGAADAPSLLAVQHKKHVSVWQLGPSTTEKSKGLMSQ SORARGS_7136_PE2 NOISO ------------------------------------------------------------ SPETRGS_4731_PE4 NOISO EAKFGNSRVIGQFEHVCGLSWAQSAMTDMPTLLAIQHKKHVTVWQLCPSTVGSSKWLVSQ TARSY37049_PE1 NOISO EAKFGDSRVIGQFEYVCRLSWATPVTADTPILLAVQHEKHVTVWQLCPSPMETSKWLMSQ TETNG14_PE545 NOISO EVKFGDTNVIGQFEHVFGLFWGPLCCSDSPALLAVQHKKHVTVWQLQLSALEQNKLLCTQ TUPGBGS_4558_PE2 NOISO EAQFGDSKVIGQFEHVCALSWAPPGTADTPALLAVQHKKHVTVWQMCLSTTETSKWLMSQ TURTRGS_2798_PE3 NOISO EAKFGDSAVIGQFEHVYRVSWAPPGTADTPALLAVQHKKHVIVWQLCPSTTETSKWLMSQ XENTR180_2_PE1 NOISO EPKFGNSIVVGQFEHVHGLYWGPFLGNDTPALLAVQHKKHVTVWQLCYSPLDKNKLVVSQ MATCH CONSENSUS E??FGDS?V?GQFE?V?G??W?P??????P?LLAVQH?KHV?VWQL??S?????K????Q

AILMEGL192369_1_4_PE9 NOISO TCEIRRSLPVLPQGCVWHPKSAVLAVLTAQDVSIFPSVHG-EGPRVKADI-DTGGFIHCA ANOCA3_9_PE3 NOISO ISEISELFPILPQGCVWHPNKEILAVLTTRDTSVLHSIRV-NSSRIKADI-KGTGLIHCA ANOCA3_9_PE4 NOISO TCEVGEPFQLLPQGCVWHPKRDILSVLTKRDASVLYAVRS-DNSRVKADI-KSSGLIHCA BOVIN11_80_PE9 NOISO PCEIRQSCPVLPQGCVWHPESAILTVLTAWDVSVFYNIHC-DSSQVKVDI-STEGLIYCA CALJA14_89_PE17 NOISO TCEIRGSLPVLPQGCVWHPKYAILTVLTTQDVSIFPNVHY-DNSQVKVDI-NTQGRIHCA CANFA17_22_PE8 ENSCAFG00000003949 ICEIRQSLPVLPQGCVWHPKSAVLAVLTAQDVSVFPSVHC-DCSRVKVDI-DTQGLIHCA CANFA17_22_PE9 ISOFORMIN ICEIRQSLPVLPQGCVWHPKSAVLAVLTAQDVSVFPSVHC-DCSRVKVDI-DTQGLIHCA CAVPO18_7_PE5 NOISO TARITASDPVLPQGCVWHPKDAVLTVLTACDASVFPSVHH-DSTRVRVDL-GAHGRIHCA CHICK3_PE1462 NOISO ICDISEPFPVLPQGCVWHPKKEILAVLTTRDASVLHSVHL-NNCRIKADI-KGSGLIHCA CHICK3_PE1463 ENSGALG00000016499 TCEIGEPFPLLSQGCVWHPKKEVLAVLTKRDASVLHTVRT-DNTRVKADI-KSSGLIHCA CHICK3_PE1464 ISOFORMIN TCEIGEPFPLLSQGCVWHPKKEVLAVLTKRDASVLHTVRT-DNTRVKADI-KSSGLIHCA DANRE20_47_PE11 NOISO TCEMSEPFPLLSQGCVWHPKMDVLAILTKRDASVLFSVRV-DNRRVKADI-KGSGLIHCA DASNOGS_5924_PE3 NOISO TCEIRESLPVLPQGCVWHPESAILTVLTAQDVSVFHNVRC-DSSRVKVDI-DTQGRIHCA DIPOR7709_PE1 NOISO VSEIKESLPILPQGCVWHPKNTVLVVLTVQNISVFPDIHFPNGSRIKVDI-NTQGRIHCA ECHTE81750_PE1 NOISO TCDIRESLPVLPQGCLWHPQSAVLTVLTAQDVSIFHDVHR-DSSRVKVDT-SAQGHIHCA FELCAGS_4949_PE2 NOISO TCEIRESLPVLPQGCVWHPESAVLAVLTAQRVSVFHSVHC-DSSRVNADI-DTQGLIHCA FUGRU16_1_PE12 ENSTRUG00000004936 TCEMSEPFPLLSHGCVWHPKLDILAVLTKRDTSVLFSVRV-DNRRTKADI-KDSGLIHCA FUGRU16_1_PE13 ISOFORMIN TCEMSEPFPLLSHGCVWHPKLDILAVLTKRDTSVLFSVRV-DNRRTKADI-KDSGLIHCA FUGRU16_1_PE14 ISOFORMIN TCEMSEPFPLLSHGCVWHPKLDILAVLTKRDTSVLFSVRV-DNRRTKADI-KDSGLIHCA FUGRU16_1_PE15 ISOFORMIN TCEMSEPFPLLSHGCVWHPKLDILAVLTKRDTSVLFSVRV-DNRRTKADI-KDSGLIHCA GASACGROUPXVIII_14_PE60 ENSGACG00000012380 TCEMSEPFPLLSQGCVWHPKLDILVVLTKKDASLLFSVRV-DNRRIKADI-KGSGLIHCA GASACGROUPXVIII_14_PE61 ISOFORMIN TCEMSEPFPLLSQGCVWHPKLDILVVLTKKDASLLFSVRV-DNRRIKADI-KGSGLIHCA GORGO2A_26_PE6 NOISO TCEIRGSLPILPHGCVWHPKCAILTVLTAQDVSIFPNVHS-DDSQVKADI-NTQGRIHCA HORSE15_74_PE14 NOISO TCEIRKSFPILPQGCVWHPKSAVLAVLTAQDVSIFHNVHC-DSSWVKATI-DTQGLIHCA HS2_PE405 ENSG00000163026 TCEIRGSLPILPQGCVWHPKCAILTVLTAQDVSIFPNVHS-DDSQVKADI-NTQGRIHCA HS2_PE406 ISOFORMIN TCEIRGSLPILPQGCVWHPKCAILTVLTAQDVSIFPNVHS-DDSQVKADI-NTQGRIHCA LAMPAGS_1066_1_PE3 NOISO NCEIRQSLPVLPQGCVWHPKIAVLTVLTAQDVSIFHNVHC-NNSQVKVDL-NTQGLIHCA LOXAF20_38_PE7 NOISO TCEIRESLAVLPQGCVWHPKSAVLTVLTAWDVSVFPNVHC-DNSRIKVDL-NTQGHIHCA MACEUSCAFFOLD41370_PE1 NOISO TCEIGEPFPVLPPGCVWHPHNAILTVLTSRDVSILHSVHC-DNSRVKADLVKVQGFVHCA MACMU13_24_PE8 ISOFORMIN TCEIRGSLPILPQGCVWHPKCAILTVLTAQDVSIFPNVHS-DNSQVKADI-NTQDRIHCA MACMU13_24_PE9 ENSMMUG00000012340 TCEIRGSLPILPQGCVWHPKCAILTVLTAQDVSIFPNVHS-DNSQVKADI-NTQDRIHCA MICMUGS_3671_1_PE4 NOISO TCEIRESLPVLPQGCLWHPKNPVLTVLTTQDVSVFPDVQY-DSSRVKADI-SILSHIHCA MONDO1_764_PE8 ENSMODG00000009400 TCEIGEPFSVLPQGCVWHPKKAILTVLTSHEVSVLPSVHC-DSTRVKADLVKVQGFVHCG MONDO1_764_PE9 ISOFORMIN TCEIGEPFSVLPQGCVWHPKKAILTVLTSHEVSVLPSVHC-DSTRVKADLVKVQGFVHCG MONDOUN_31_PE18 NOISO TCEIGEAFPVLAQGCVWHPKKAILTVLNSHEVSVLPSVHC-DSTRVKADLFKVQDFVHCG MONDOUN_32_PE1 ENSMODG00000002152 TCEIGEPFPVLAQGCVWHPKKAILTVLTSHEVSVLPSVHC-DSTRVKADLIKVQGFVHCG MONDOUN_32_PE2 ISOFORMIN TCEIGEPFPVLAQGCVWHPKKAILTVLTSHEVSVLPSVHC-DSTRVKADLIKVQGFVHCG MOUSE12_PE46 ISOFORMIN TSEVRESLPILPRGCVWHPKDAVLTVLTAQGVSIFPNVHQ-DGSRVKVDV-NTKGRVYCA MOUSE12_PE47 ENSMUSG00000051721 TSEVRESLPILPRGCVWHPKDAVLTVLTAQGVSIFPNVHQ-DGSRVKVDV-NTKGRVYCA MYOLUGS_4810_PE3 NOISO TCEIREPRPVLPQGCVWHPQSAVLTVLTARDVSIAHNVHC-DGSRVKADS-SAQGLIHCA ORNAN2_7_PE6 NOISO SCEVREPFPVLPQGCIWHPKKEILTILTNQDASVIYSVRC-DSIIVKADI-KASGLIHCA ORYLA24_3_PE7 NOISO TCEMSEPFPLLSQGCVWHPKLDILAVLTKKDASVLFSVRV-DNRRIKADV-RGGGLIHCA OTOGA4515_PE3 NOISO ACETRESLPVLPQGCLWHPKNAVLTVLTAQDVSVFPNVHC-DSSRVKLDI-NTQGRIHCA PANTR2A_26_PE5 ENSPTRG00000011707 TCEIRGSLPILPQGCVWHPKCAILTVLTAQDVSIFPNVHS-DDSQVKADI-NTQGRIHCA PANTR2A_26_PE6 ISOFORMIN TCEIRGSLPILPQGCVWHPKCAILTVLTAQDVSIFPNVHS-DDSQVKADI-NTQGRIHCA PIG3_109_PE13 NOISO TCEIKQSFPVLPQGCVWHPKSAVLTVLTAQDVSVFHNVHR-DSSQVKVDI-NPQGLIHCA POEGU3_109_PE6 NOISO LCDISEPYPVLPQGCVWHPSKEVLAVLTTRDASVLPSVHL-NNSRINADI-KGSGLIHCA POEGU3_110_PE1 NOISO TCEVGEPFPLLSQGCVWHPKKEVLAVLTKRDASVLHAVRT-DNTRVKAEI-KSSGVIHCA PONPY2A_91_PE8 NOISO TCEIRGSLPILPQGCVWHPKCAILTVLTAQDVSIFPNVHS-DNSQVKADI-NTQGRIHCA PTEVAGS_3150_PE3 NOISO TCEIRESSPVLPQGCVWHPKSAVLTVLTAQDVSIFHDVHC-DSSRVRVDS-NTQGLIHCA RABIT2_177_PE8 NOISO TCEIRESLPVLPQGCVWHPNGAVLTVLTARDVSVFPNVQW-DSSRVSVNI-STPGRIHCA SORARGS_7136_PE2 NOISO ------------------------------------------------------------ SPETRGS_4731_PE4 NOISO TSEIRESLPLLPQGCVWHPKNAVLTVMTSQNVSVFPDVHC-DSSRIKVDI-NTQGRIHCG TARSY37049_PE1 NOISO TCEISESLPVLPQGCVWHPKSAILTVLTAQDVSVFPYVHC-DNSRVKADI-ATQGRIHCA TETNG14_PE545 NOISO TCEMSEPFPLLSHGCVWHPKLDILAVLTKRDTSVLFSVRV-DNRRTKADI-KGSGIIHCA TUPGBGS_4558_PE2 NOISO TCEIRESLSVLPQGCVWHPKNAILAVLTAQNVSVFPNVHR-DSSQVKVDI-NAQYRIHCA TURTRGS_2798_PE3 NOISO TCEIRQSLPVLPQGCVWHPKSAVLTVLTAQDVSVFHNVHW-DSSQVKVDI-STQGLIHCA XENTR180_2_PE1 NOISO TCEIGDPFPVLPQGCTWHPSKDILVVLTKRDVSVLYAVRY-ENTSIKADV-KSSGLIHCA MATCH CONSENSUS TCE?????P?L?QGCVWHPK???L?VLT????S????V???D????K?D?????G?IHCA

AILMEGL192369_1_4_PE9 NOISO CWTRDGRRLVVAVGSSLHSFIWDSAQKTLCRCSFYPVFDVDSCVRAIGATADSKVAVATE ANOCA3_9_PE3 NOISO CWTEEGNRLVVGIGSALHSYIWDDDQKTLNACSFCPIFDVGGYICAIEATLNSQVAVATE ANOCA3_9_PE4 NOISO CWTKDGNRLVVAISTALHSYIWDDARKTLSACSFCPIFDVGSYICAIEATVDFQIAVATE BOVIN11_80_PE9 NOISO CWTQDGQRLVVAAGSSLHSYIWDSAQKTLHRCSLCPIFDVDSYVRSIRATVDSQVAIATE CALJA14_89_PE17 NOISO CWTQDGLRLVVAIGSSLLSYIWESAQKTLHRCASCLVFDMDSHVCSITATVDSQVAIATE CANFA17_22_PE8 ENSCAFG00000003949 CWTQDGRRLVVASGSSLHSYIWDSAQKTLHRCSFHPVFDVDSHVRSLSATVNSQVAIATE CANFA17_22_PE9 ISOFORMIN CWTQDGRRLVVASGSSLHSYIWDSAQKTLHRCSFHPVFDVDSHVRSLSATVNSQVAIATE CAVPO18_7_PE5 NOISO CWTRDGRRLVVAVGSCLHSYVWDSTQRTLHRCSACPTFSVDSCVCSITATVDSEVAVTTE CHICK3_PE1462 NOISO CWTKEGNRLVVGVGSALHSYIWDDTQKTLNACTFCPIFDVGGYICAVEATSNFQIAVATE CHICK3_PE1463 ENSGALG00000016499 CWTKDGNRLVVAIGSALHSYIWDDAQKTLNACSFCPVFDVGGYICAIEATLDFQIAVATE CHICK3_PE1464 ISOFORMIN CWTKDGNRLVVAIGSALHSYIWDDAQKTLNACSFCPVFDVGGYICAIEATLDFQIAVATE DANRE20_47_PE11 NOISO CWTKDGTRLVVAIGSALHSYTWNDIQKSLVPCSFCPIFDVGGYICAIESTDEAQVAVATE DASNOGS_5924_PE3 NOISO CWTQGGQRLVVAVGSSLHSYIWDSAQKTLRRCSFCPVLHVDSHIRSIRATVDSQVAVATE DIPOR7709_PE1 NOISO CWTPDGQRLVVAVGSSLHSYIWDSYQKTLDKCSFCPVFDVDSSVCSIRATVDSQIAVTTE ECHTE81750_PE1 NOISO CWTRDGQRLVVAVGRSLHSYIWDSAQKTLHRCSFCPVFGVDSYVRAIGATVNSQVAVATE FELCAGS_4949_PE2 NOISO SWTQDGQRLVVAAGSSLHSYIWDSAQKTLRRCSFHPVFDVDSSVRSIRATVDSQVAVATE FUGRU16_1_PE12 ENSTRUG00000004936 CWTKDGTRLVVAIGSALHSYIWNDIQKSLVACSFCPMFDVGGYVCAIAATGEAQVAVATE FUGRU16_1_PE13 ISOFORMIN CWTKDGTRLVVAIGSALHSYIWNDIQKSLVACSFCPMFDVGGYVCAIAATGEAQVAVATE FUGRU16_1_PE14 ISOFORMIN CWTKDGTRLVVAIGSALHSYIWNDIQKSLVACSFCPMFDVGGYVCAIAATGEAQVAVATE FUGRU16_1_PE15 ISOFORMIN CWTKDGTRLVVAIGSALHSYIWNDIQKSLVACSFCPMFDVGGYVCAIAATGEAQVAVATE GASACGROUPXVIII_14_PE60 ENSGACG00000012380 CWTKDGTRLVVALGSSLHSYIWNDIQKSLVACSFCPVFDVGGYICAMEATGEAQVAVATE GASACGROUPXVIII_14_PE61 ISOFORMIN CWTKDGTRLVVALGSSLHSYIWNDIQKSLVACSFCPVFDVGGYICAMEATGEAQVAVATE GORGO2A_26_PE6 NOISO CWTQDGLRLVVAVGSSLHSYIWDSAQKTLHRCSSCLVFDVDSHVCSITATVDSQVAIATE HORSE15_74_PE14 NOISO CWTQDGQRLVVAVGSSLHSYIWDSAQKTLHRCPFYPVFDVDSCVRSIGATVESQVAVATE HS2_PE405 ENSG00000163026 CWTQDGLRLVVAVGSSLHSYIWDSAQKTLHRCSSCLVFDVDSHVCSITATVDSQVAIATE HS2_PE406 ISOFORMIN CWTQDGLRLVVAVGSSLHSYIWDSAQKTLHRCSSCLVFDVDSHVCSITATVDSQVAIATE LAMPAGS_1066_1_PE3 NOISO CWTQNGQMLVVAVGSSLHSYIWDSAQKALHRCSFCPVFDVDSHVCSIGATVNSEVAIATE LOXAF20_38_PE7 NOISO CWTQDGQRLVVAVGSSLYSYIWDSAHKALHRCSFCPVFDADSYIRAIRATVDSQVAITTE MACEUSCAFFOLD41370_PE1 NOISO CWTLDGQRLVVAVGSALHSFMWDDSQKTLHACSFCPVFDVGSHICSVLATVDVQIAVATE MACMU13_24_PE8 ISOFORMIN CWTQDGLRLVVAVGSGLHSYIWDSAQKTLHRCSSCLVFDVDSHVCSITATVDSQVAIATE MACMU13_24_PE9 ENSMMUG00000012340 CWTQDGLRLVVAVGSGLHSYIWDSAQKTLHRCSSCLVFDVDSHVCSITATVDSQVAIATE MICMUGS_3671_1_PE4 NOISO CWTQDGQRLVVAVGSSLQSYIWDSAEKTLQKYSFCPVFEVDSRICSISATVDSQVAIATE MONDO1_764_PE8 ENSMODG00000009400 CWTHDGQRLVVALGSTLHSFTWDDSQKSLQPCTFCPVFDLGKNICSVLATVDMQVAVATE MONDO1_764_PE9 ISOFORMIN CWTHDGQRLVVALGSTLHSFTWDDSQKSLQPCTFCPVFDLGKNICSVLATVDMQVAVATE MONDOUN_31_PE18 NOISO CWTHDGQRLVVAVGSALHSFMWDDSQKSLQPCAFCPVFDMGKNICSVLATVDMQVAVATE MONDOUN_32_PE1 ENSMODG00000002152 CWTHDGQRLVVAVGSALHSFIWDDSQKSLQPCAFCPVFDMGKNICSVLATVDMQIAVATE MONDOUN_32_PE2 ISOFORMIN CWTHDGQRLVVAVGSALHSFIWDDSQKSLQPCAFCPVFDMGKNICSVLATVDMQIAVATE MOUSE12_PE46 ISOFORMIN CWTLDGQRLVVAIDSNLHSYIWDSSQKSLHSCSFCPVFPVNCSIRSIEATGNSQVAIATE MOUSE12_PE47 ENSMUSG00000051721 CWTLDGQRLVVAIDSNLHSYIWDSSQKSLHSCSFCPVFPVNCSIRSIEATGNSQVAIATE MYOLUGS_4810_PE3 NOISO CWTQDGQRLVVAVGSSLHSYIWDSAQKTLQRCSFCPVLDVLSDVRSIGAAVDSQVVLATE ORNAN2_7_PE6 NOISO CWTEEGNRLVLAIGSALHSYIWDSTRKTLLPCSFCPIFDVGGYICATEATVGLQIAVATE ORYLA24_3_PE7 NOISO CWTKDGTRLVVAIGSALHSYIWNDIQKSLAACSFCPVFDIGGYICAIEATGEAQVAVATE OTOGA4515_PE3 NOISO CWTQDGQRLVVAVGSSLHSYIWDSAQKALHKCSFCPVFDVDSCVCSISATMDSQIALATE PANTR2A_26_PE5 ENSPTRG00000011707 CWTQDGLRLVVAVGSSLHSYIWDSAQKTLHRCSSCLVFDVDSHVCSITATVDSQVAIATE PANTR2A_26_PE6 ISOFORMIN CWTQDGLRLVVAVGSSLHSYIWDSAQKTLHRCSSCLVFDVDSHVCSITATVDSQVAIATE PIG3_109_PE13 NOISO CWTQDGQRLVVVAGSSLHSYIWDSVQKTLHRCAFCPVFDVDSCVRAVCATVDSQVAIATE POEGU3_109_PE6 NOISO CWTKEGNRLVVGVGSALHSYIWDDDQKTLSACSFCPIFDVGGYICAVEATQNLQVAVATE POEGU3_110_PE1 NOISO CWTKDGNRLVVAIGSTLHSYIWDNAQKTLNICSFCPVFDVGGYICAIEATLDFQIAVATE PONPY2A_91_PE8 NOISO CWTQDGLRLVVAVGSTLHSYIWDSAQKTLHRCSSCLVFDVDSHVCSITATVDSQVAIATE PTEVAGS_3150_PE3 NOISO CWTRDGQRLVVAVGSSLHSYIWDSAQKTLHRCSFCSVFDVDSYVRSIGATVDSQVAIATE RABIT2_177_PE8 NOISO CWTQDGQRLVVAVGSCLHSFIWDSARKTLHRCSLSPVFDVDSSVRCITATVDSQVAVATE SORARGS_7136_PE2 NOISO --------------------------------------DVDSSVCCISATVDTQVILATE SPETRGS_4731_PE4 NOISO CWTQDGQRLVVAVGSSLHSFVWDSPQKILHRSSLCPVFDVDSYICSMRATVDSQVAIATE TARSY37049_PE1 NOISO CWTQDGQRLVVAVGSSLHSYIWDSAQKILYRCFFCPVFDVGSYICSIRATMDSQVAIATE TETNG14_PE545 NOISO CWTKDGTRLVVAIGSALHSYIWNDIQKSLVACSFCPIFDVGGYICAIAATGEAQVAVATE TUPGBGS_4558_PE2 NOISO SWTQDGQRLVVAVGSSLHSYIWDSAQKALHRCSFCPVFDVVSSISAIRATVDSQVAIATE TURTRGS_2798_PE3 NOISO CWTPDGQRLVVAVGSSVHSYIWDSAQKTLHRCSFCPVFDVASYVRSIGATVDSQVAIATE XENTR180_2_PE1 NOISO CWTKDGSRLVVAIGSALHSYIWDSKQKSLNACAFCPVFDIGGYICAIESTVDSQVAVSTE MATCH : . :: :: ::** CONSENSUS CWT?DG?RLVVA?GS?LHSYIWD??QK?L??C??CP?FDV????????AT???QVA?ATE

AILMEGL192369_1_4_PE9 NOISO LPLDKICGLNASETFDILPGGEDTRLC---ASPVTDEVPTEDKGAVASETNFESSISP-V ANOCA3_9_PE3 NOISO LPLDKICTLNAGISFEMPAEVVGNSVPSQTTSLSCEEEHTVDVGKKLPDQEKSGS----L ANOCA3_9_PE4 NOISO LPLDKICGLNAGITFELPVGTETGSVTSQSTLVLGDEEYSMDLRRKSIDSDKSAT-IESV BOVIN11_80_PE9 NOISO LPLDKICGLNASGTFDIPPSGEDTCLH---ALPVTDRVS--------SETNSETPV---- CALJA14_89_PE17 NOISO LPLDKICGLNASQTFNVPPNSKDMTLY---ALPVIGEVPSVDKEAADSETNSEVS----V CANFA17_22_PE8 ENSCAFG00000003949 LPLDKICGLNASETFAIPPGGEDTHLC---TSPITEEVPIGDEGAVASETNFETSVSP-V CANFA17_22_PE9 ISOFORMIN LPLDKICGLNASETFAIPPGGEDTHLC---TSPITEEVPIGDEGAVASETNFETSVSP-V CAVPO18_7_PE5 NOISO LPLDKICSLTVSESAAVPANGGDAGLR---ISPAAGEVAAGNEEAAACETDSETAASP-- CHICK3_PE1462 NOISO LPLDKICGLNAGVAFEVPASIETESFPSQSS-LCGEEEYSMDGGKKVLDVEKPMS----A CHICK3_PE1463 ENSGALG00000016499 LPLDNICGLNAGITFDMPSGAETSSLTSQSTTALGDEEYSMDLRRKSTDSDRSGT-VDSV CHICK3_PE1464 ISOFORMIN LPLDNICGLNAGITFDMPSGAETSSLTSQSTTALGDEEYSMDLRRKSTDSDRSGT-VDSV DANRE20_47_PE11 NOISO LPLDKICGLNAGMAFDLPNESEGLCRPSAA---LTVDTDYYLDRRRSCDSERSGH----- DASNOGS_5924_PE3 NOISO LPLDRICGLNASETTDIAPGGGDTGLH---ALPVIGDMPPLDKGPVASETNSEKLASPSL DIPOR7709_PE1 NOISO LPLDKLCRLNAAETLDVPHNGEDTGPP---VLPVVGEGPCADKGATGPETKSEISVSP-- ECHTE81750_PE1 NOISO LPLDQICGLNASEAFDVPASGKDTYLC---TSPVTGAGPSLGKGASASTTSSEPTASSSF FELCAGS_4949_PE2 NOISO LPLDKICGLNASEIFDVPPSGEDPCLC---TFPVIDEVPTTGKGAVASKTSVETSVSP-L FUGRU16_1_PE12 ENSTRUG00000004936 LPLDKICGLNAGMAFDLPSESLPS------G-DTSDNDSVVDSRRRSVDLDRAYN----- FUGRU16_1_PE13 ISOFORMIN LPLDKICGLNAGMAFDLPSESLPS------G-DTSDNDSVVDSRRRSVDLDRAYN----- FUGRU16_1_PE14 ISOFORMIN LPLDKICGLNAGMAFDLPSESLPS------G-DTSDNDSVVDSRRRSVDLDRAYN----- FUGRU16_1_PE15 ISOFORMIN LPLDKICGLNAGMAFDLPSESLPS------G-DTSDNDSVVDSRRRSVDLDRAYN----- GASACGROUPXVIII_14_PE60 ENSGACG00000012380 LPLDKICGLNAGMAFDLASESESLHSHGSST-VFSEDDSGVDSRRISFESERSYI----- GASACGROUPXVIII_14_PE61 ISOFORMIN LPLDKICGLNAGMAFDLASESESLHSHGSST-VFSEDDSGVDSRRISFESERSYI----- GORGO2A_26_PE6 NOISO LPLDKICGLNASETFNIPPNSKDMTPY---ALPVIGEVPSMDKEATDSETNSEVS----V HORSE15_74_PE14 NOISO LPLDKICGLSASETLDVLPSGEDTCLC---SLPLEEGLF-VDKEAFASETNSETSVSP-F HS2_PE405 ENSG00000163026 LPLDKICGLNASETFNIPPNSKDMTPY---ALPVIGEVRSMDKEATDSETNSEVS----V HS2_PE406 ISOFORMIN LPLDKICGLNASETFNIPPNSKDMTPY---ALPVIGEVRSMDKEATDSETNSEVS----V LAMPAGS_1066_1_PE3 NOISO LPLGKICGLNASGTFDVAPSGEDTCSY---TLPVTDEVSSVDNDAVASETSSETPVSP-F LOXAF20_38_PE7 NOISO LPLDKICGLNASETFDIPTSGKDTYLY---TLPVIGEVPSVDKGADTSETNSEIPVSPSF MACEUSCAFFOLD41370_PE1 NOISO LPLDKICSLHSMETFEMSAKRDTNP---PSSLAAISEEPSMDPRKVSPDSEPFSS-SPSL MACMU13_24_PE8 ISOFORMIN LPLDKICGLNASETFNVPPNSKDTTLY---ALPVIGEVPSIDKEATDSEKDSEVS----V MACMU13_24_PE9 ENSMMUG00000012340 LPLDKICGLNASETFNVPPNSKDTTLY---ALPVIGEVPSIDKEATDSEKDSEVS----V MICMUGS_3671_1_PE4 NOISO LPLDKICGLNASDIFDVPPNGEDVTMY---NFPVTGDVPCMDEGATVTETNSEIPLSP-- MONDO1_764_PE8 ENSMODG00000009400 LPLDKICSLNLIEAFEMPTMEETQPSTTPSS-PVITEETLIDTGKVSPDSEPSSS-SASL MONDO1_764_PE9 ISOFORMIN LPLDKICSLNLIEAFEMPTMEETQPSTTPSS-PVITEETLIDTGKVSPDSEPSSS-SASL MONDOUN_31_PE18 NOISO LPLDRICGLNSVETFEMPTVEEAQPSTTPSSSAVIAEEALMDTGKVSPDSERSSS-LASL MONDOUN_32_PE1 ENSMODG00000002152 LPLDKICGLNSVEPFEMPTVEEAQPSTTPSTSAVIAEEALMDTGKVSPDSERSSS-SASL MONDOUN_32_PE2 ISOFORMIN LPLDKICGLNSVEPFEMPTVEEAQPSTTPSTSAVIAEEALMDTGKVSPDSERSSS-SASL MOUSE12_PE46 ISOFORMIN LPLHKLCSLNASEALDGPPNGDDGSVH---TRPVDEQVATMDM-------NSGVTVSP-- MOUSE12_PE47 ENSMUSG00000051721 LPLHKLCSLNASEALDGPPNGDDGSVH---TRPVDEQVATMDM-------NSGVTVSP-- MYOLUGS_4810_PE3 NOISO LPIGKICGLNASETFGVPPSSEDTCLY---TSPVTDEMPSVDKGAASCGTNSDTSVSP-F ORNAN2_7_PE6 NOISO LPLDKICGLNAGMAFDIPADGESNSFPSQSTLLVADEELPKAPGKAAQDPEKSTS----- ORYLA24_3_PE7 NOISO LPLDKICGFNAGIAFDLPTDAEPLQSQGSHV-LMSDDDGVLDSRRRSFESERSYI----- OTOGA4515_PE3 NOISO LPLDKICGLNASETFDVPPNGKDTSLY---TLPVIGKVPSVTPGAVNSETNSEISLSPSF PANTR2A_26_PE5 ENSPTRG00000011707 LPLDRICGLNASETFNIPPNSKDMTPY---ALPVIGEVPSMDKEATDSETNSEVS----V PANTR2A_26_PE6 ISOFORMIN LPLDRICGLNASETFNIPPNSKDMTPY---ALPVIGEVPSMDKEATDSETNSEVS----V PIG3_109_PE13 NOISO LPLAKICGLNSSGTFDIPPSAEDTCLY---TLPVGDEG------------SSETRVSP-F POEGU3_109_PE6 NOISO LPLDKICGLNAGVAFEVPSSVETESFPSQSS-LCGEEEYSLDGGKKSLDSEKPLS----V POEGU3_110_PE1 NOISO LPLDNICGFNAGIAFDVPSGTEGVSLISQAALVLGDEEYSMDTRRKSIDSDRSG--VDSV PONPY2A_91_PE8 NOISO LPLDKICGLNASETFNIPPNSKDMTPY---ALPVIGEVPSMDKEATDSETNSEVS----V PTEVAGS_3150_PE3 NOISO LPLDKICGLNASETLIVPPSIEDTSLY---ASPVIDEVPSVEKGVTPCETNSEASVSP-F RABIT2_177_PE8 NOISO LPLDKICSLNASETFEAPLSGANPGLD---TFLVADDVPSVDKGALASETDSETSPVS-- SORARGS_7136_PE2 NOISO LPLGKICGLHASASLGVRTSGDDTCPS---ALPLSEGAPSAGKEADASGTKPETFLTP-- SPETRGS_4731_PE4 NOISO LPLDKICSLNALETFDVPLSGEDTHLP---TFPVIDEMPSVDKGEIASESNSEISVSP-- TARSY37049_PE1 NOISO LPLAKLCGLNASEVFVVTPNVEDTSLN---TLPVPTEVSSVGVEAMDSETSSEIS----V TETNG14_PE545 NOISO LPLDKICSLNAGMAFDLPSESLLS------G-DVSDSDSVVDSRRRSVDSERAYI----- TUPGBGS_4558_PE2 NOISO LPLAKICGLNESETFDNPLNGEDTCPC---TLPIIDELPSVDKGAITSETNSEESVSPPV TURTRGS_2798_PE3 NOISO LPLDKICGLNASGTFDVPPSSEGTCLY---TLPVIDEVS--------SETNSETPVSP-F XENTR180_2_PE1 NOISO LPLDRICALNAGIAFDVPASSEI-TISSQPGLLLMEEEFSMDVVQKSADSGSLT--TDSL MATCH **: .:* : CONSENSUS LPLDKIC?LNA???F??P??????????????????????????????????????????

AILMEGL192369_1_4_PE9 NOISO SSSFSDPLDLTHIHLNTSKSEGSSLICLRQKDCLTGTGLDSSHLVLVTFEKEVTQTRKIT ANOCA3_9_PE3 NOISO VTSASSPVDLTHLSSNKHRSENSPLINLKPKDYLTGSGQDASHLILVTFERKVTATKKVS ANOCA3_9_PE4 NOISO ASSSSGPVDLMHILANHRRSDPSPLITLRRKDYPSGTGQDSSHLILVTFEGKVTTTRKVS BOVIN11_80_PE9 NOISO SSSYSEPLDLTHIHFNRFKSEGSSLTCLRKKDYLTGTGLDSSHLVLLTFEKEVTCNRKVI CALJA14_89_PE17 NOISO SSSYLEPLDLTHIHFNQSKSENNSLICLRKKDYLTGTGQDSSHLVLVTFKKAVTMTRKVT CANFA17_22_PE8 ENSCAFG00000003949 SS-SSDPLDLTHIHFNTATSESSSLICLRKKDFLTGTGLDSSHLVLVTFEKEVTQTKKVT CANFA17_22_PE9 ISOFORMIN SS-SSDPLDLTHIHFNTATSESSSLICLRKKDFLTGTGLDSSHLVLVTFEKEVTQTKKVT CAVPO18_7_PE5 NOISO --SSSGLLDLSHLHFSGPRCEGSALMCLREEDHVAGTGQDSALLVLVTFGKEVTTTRKVT CHICK3_PE1462 NOISO ---VTSPVDLTHILSSKPGADSSPLLHLRPKDYLTGSGQDSSHLILVTFEKKVTSTKKVS CHICK3_PE1463 ENSGALG00000016499 ASSSSGPLDLTHILANHRRSDPSPLITLKRKDSAAINGQDSSYLILVTFERKVTTTRKVN CHICK3_PE1464 ISOFORMIN ASSSSGPLDLTHILANHRRSDPSPLITLKRKDSAAINGQDSSYLILVTFERKVTTTRKVN DANRE20_47_PE11 NOISO --ASSGPIDLTNLLAKHRKSDPSPLIHLRKRDNLTGTGQDSSHLILVTYERKVTTTRKVS DASNOGS_5924_PE3 NOISO SSSSLHPLDLTHLHFSTSRSEGGSPICLRQKDFLTGTDQDSSQLVLVTYEREVPRTRKVG DIPOR7709_PE1 NOISO --TFSDPLDLTHIRFNRPTSERSPLIYLSKKDHLTGTGQDSSHLVLVTFKKAVTMTRKAT ECHTE81750_PE1 NOISO SSPSSDPLDLTHIRFSRSGAENGSLLCLRRKDDLTGTGQDSSHLVLVTFGKEATMTRKVT FELCAGS_4949_PE2 NOISO SS-FSDPLDLTHMHFNTSKSEGSSLICLRKKDYLTGTGMDSSHLVLVTFEKEVTQTRKVT FUGRU16_1_PE12 ENSTRUG00000004936 --PASGPLDLTHLLARHRRSDPSPLIHLRHRDSITGSGQDSSHLILVTYERKVTTTRKVS FUGRU16_1_PE13 ISOFORMIN --PASGPLDLTHLLARHRRSDPSPLIHLRHRDSITGSGQDSSHLILVTYERKVTTTRKVS FUGRU16_1_PE14 ISOFORMIN --PASGPLDLTHLLARHRRSDPSPLIHLRHRDSITGSGQDSSHLILVTYERKVTTTRKVS FUGRU16_1_PE15 ISOFORMIN --PASGPLDLTHLLARHRRSDPSPLIHLRHRDSITGSGQDSSHLILVTYERKVTTTRKVS GASACGROUPXVIII_14_PE60 ENSGACG00000012380 --PSSGPLDLTHLLARHRRSDPSPLLHLRRRDTISGSGQDSSHLILVTYERKVTTSRKVS GASACGROUPXVIII_14_PE61 ISOFORMIN --PSSGPLDLTHLLARHRRSDPSPLLHLRRRDTISGSGQDSSHLILVTYERKVTTSRKVS GORGO2A_26_PE6 NOISO SSSYLEPLDLTHIHFNQHKSEGNSLICLRKKDYLTGTGQDSSHLVLVTFKKAVTMTRKVT HORSE15_74_PE14 NOISO SS-SSDPVDLTHIQFSRSESEGNSLICLRKKDHLTGTGLDSSYLALVTFEQVVTQTRKVA HS2_PE405 ENSG00000163026 SSSYLEPLDLTHIHFNQHKSEGNSLICLRKKDYLTGTGQDSSHLVLVTFKKAVTMTRKVT HS2_PE406 ISOFORMIN SSSYLEPLDLTHIHFNQHKSEGNSLICLRKKDYLTGTGQDSSHLVLVTFKKAVTMTRKVT LAMPAGS_1066_1_PE3 NOISO SSSFSDLLDLTHIHFSRSKSEGSSLICLRKKDYLTGTGLDSSHLVLLNFEKEVTQNRKVT LOXAF20_38_PE7 NOISO SSASSDPLDLTHVRFNKSGSQGSSLICLRKKDYLTGTGQDSSHLVLVTFEKEVTRTRKVT MACEUSCAFFOLD41370_PE1 NOISO SSSSLDSLDITPMLSRSHGRDLSSVFHLQEKGCLSGAGQDSSHLILVTFDRMVTTTRKVG MACMU13_24_PE8 ISOFORMIN SSSYLEPLDLTHIHFSQHKSEGNSLICLRKKDYLTGTGQDSSHLVLVTFKKAVTMTRKVT MACMU13_24_PE9 ENSMMUG00000012340 SSSYLEPLDLTHIHFSQHKSEGNSLICLRKKDYLTGTGQDSSHLVLVTFKKAVTMTRKVT MICMUGS_3671_1_PE4 NOISO --SCLDPLDLTGMQFSQHNSEGSSLISLGKKDYLTGTGQDSSHLVLVTFKEAVPMSRKVT MONDO1_764_PE8 ENSMODG00000009400 SSSSLDSLDLTQTLPGNYRSDPSSLFHLREKEYLARAGQESSHLVLVTLDRMVTTTWKVG MONDO1_764_PE9 ISOFORMIN SSSSLDSLDLTQTLPGNYRSDPSSLFHLREKEYLARAGQESSHLVLVTLDRMVTTTWKVG MONDOUN_31_PE18 NOISO SSSSLDSLDLTQMLPRNYQSDTNFFFHLREKEYLARAGKESSHLVLVTFDRMVTTTRKVG MONDOUN_32_PE1 ENSMODG00000002152 SSSSLDSLDLTQMLPRNYQSDTNFFFHLREKEYLARAGKESSHLVLVTFDRMVTTTRKVG MONDOUN_32_PE2 ISOFORMIN SSSSLDSLDLTQMLPRNYQSDTNFFFHLREKEYLARAGKESSHLVLVTFDRMVTTTRKVG MOUSE12_PE46 ISOFORMIN ---FSVPLDLTHIHFNPSQAEQSSLICLRKKDYLTGTGQDSSHLILVTFKKAITITKKVA MOUSE12_PE47 ENSMUSG00000051721 ---FSVPLDLTHIHFNPSQAEQSSLICLRKKDYLTGTGQDSSHLILVTFKKAITITKKVA MYOLUGS_4810_PE3 NOISO SS-RSDPLDLTHIRFNRSQSESNALICLRKKNYLAGTDLDSSHLILVTFAQVVTQVKKVT ORNAN2_7_PE6 NOISO -SLSPDMVDLTHVHSNNPRPRPSPLLNLKPKDYLTGSGHDSSHLILVSFEPKATTTRKVN ORYLA24_3_PE7 NOISO --PSSSALDLTHLLARHRRSDPSPLIHLRRRDTVTGSGQDCSHLVLVTFERKVTTTRKVS OTOGA4515_PE3 NOISO SSSCLDPLDLTHIQFNQRRSEGSSLISLRKKDYLTGTGQDSSHLVLVTFKEGVTMSKKVT PANTR2A_26_PE5 ENSPTRG00000011707 SSSYLEPLDLTHIHFNQHKSEGNSLICLRKKDYLTGTGQDSSHLVLVTFKKAVTMTRKVT PANTR2A_26_PE6 ISOFORMIN SSSYLEPLDLTHIHFNQHKSEGNSLICLRKKDYLTGTGQDSSHLVLVTFKKAVTMTRKVT PIG3_109_PE13 NOISO SSSSSDPLDLTHIHFNRFKSEDSSLIYLRKKDCLTGTGLDSSHLVLLTFEKEVTQNGKVT POEGU3_109_PE6 NOISO ---VTSPVDLTHILSSKQSADSSPLLHLRPKDYLTGSGQDSSHLILVTFERKVTSTKKVS POEGU3_110_PE1 NOISO ASSSSGPVDLTHILANHRRSDPSPLITLKRKDSAATNGQDSSHLILVTFERKVTTTRKVT PONPY2A_91_PE8 NOISO SSSYLEPLDLTHIHFNQHKSEGNSLICLRKKDYLTGTGQDSSHLVLVTFKKAVTMTRKVT PTEVAGS_3150_PE3 NOISO SFSFSDPLDLTHIHFSRSASESSALICLRKKDDWTRTGLDSSHLVLVTFEKEVTQTRKVT RABIT2_177_PE8 NOISO --PSTDLLDLTHISFSRPRSEGSSLICLRKKASWTGTGQDSSHMALVAFEKTVTLTGRVR SORARGS_7136_PE2 NOISO GSHFSDLVDLTHVRFKPSRSEGSSLIFLREKNCVTGTGLDSSHLVLVTFKKDVTRTRKVP SPETRGS_4731_PE4 NOISO --SFSEPLDLTHIHFNQARSEGSSLICLRQKNYLTGTGQDSSHLVLVTFKEAVTMTRKVT TARSY37049_PE1 NOISO SSSYLDPLDLTHIHFNHHRSEGDSLTCLRKKDYLTGTGRDSSHLFLVTFKKEVTMTRKVT TETNG14_PE545 NOISO --PASGPLDLTHLLARHRRSDPSPLLHLRHRDSITGSGQDSSHLILVTYERKVTTTRKVS TUPGBGS_4558_PE2 NOISO SSYYSDPLDLTHIRFNRQKSEGSSLICLRKKDYLTGTGQDSSHLVLVTFKKAVTTTKKVT TURTRGS_2798_PE3 NOISO SSSFSDPLDLTHIHFDGSKSEASSLICLRKKDYLTGTGLDSSHLVLLTFEKEVTQNRKVT XENTR180_2_PE1 NOISO A-TSPATLDLTHIV-NHSKADLNSLLNMKKKDYLTGSGQDSSHLILVNFEKKVTTTRRVS MATCH :*: . : . : . :.: : *: . : CONSENSUS ???????LDLTH???????S????L??LR?KD???G?G?DSSHL?LVTF???VT?T?KV?

AILMEGL192369_1_4_PE9 NOISO IPGILAPDLIAFNPKAQVAVVASNTCNVIFIYSVIPSRVPSIRQIQLERSEKPKGVCFLT ANOCA3_9_PE3 NOISO IPGILVPDIMTFDSKAQTVAVASNTCNLILVYSLTSSHLPNIQQIQLEKSERPKGLCFLT ANOCA3_9_PE4 NOISO IPGILVPDIIAFDLKAQTVAIASNTCNIVLVYSVTSFCMPNIQQIQLEKSERPKGLTFLT BOVIN11_80_PE9 NOISO IPGILVPDLIAFNFKAQAVAVASNTSNVIFIYSVIPLLMPNIQQIQLESNERPKGICFLT CALJA14_89_PE17 NOISO IPGILVPDLIAFNLKAQIVAVASNTCNIILIYSVVPSSVPNIQQIQLENTERPKGICFLT CANFA17_22_PE8 ENSCAFG00000003949 IPGILAPDLIAFNLKAQVVAVASNTYNIIFIYSVIPSFTPNIQQIQLERNEKPKGLCFLT CANFA17_22_PE9 ISOFORMIN IPGILAPDLIAFNLKAQVVAVASNTYNIIFIYSVIPSFTPNIQQIQLERNEKPKGLCFLT CAVPO18_7_PE5 NOISO ISGMLAPDLIAFNPKTQVVAVASNTCNVVLIYSVTPSSMPNIQQIQLENDERPKGMTFTT CHICK3_PE1462 NOISO IPGILVPDIMAFDIKTQTVSVASNTCNVILVYSLTSSNLPNIQQIQLEKNEKPKGLCFLT CHICK3_PE1463 ENSGALG00000016499 IPGILVPDIMAFDLRAQIVAVASNTSNIVLVYSVTSSCMPHIQQIQLEKNERPKGLCFLT CHICK3_PE1464 ISOFORMIN IPGILVPDIMAFDLRAQIVAVASNTSNIVLVYSVTSSCMPHIQQIQLEKNERPKGLCFLT DANRE20_47_PE11 NOISO IPGILVPDIIAFDPNGHTVAVASNTCNMILVYCITDSSMPNVQQIQLQKNERPKGVCFFT DASNOGS_5924_PE3 NOISO IPGLLVPDLMAFNLKAQVVAVASNTCNIILIYSITPSSMQNVQQIQLESSERPKGLYFLT DIPOR7709_PE1 NOISO IPGILVPDLIAFNLKAHIIAVASNTCNIILIYSVIPSSMANIQQIQLESNERPKGICFLT ECHTE81750_PE1 NOISO LPGILAPDLIAFHLQAQVVAVASSTCSTIWVYSVIPSSMPNIQQVRLESNERPKGLTFLT FELCAGS_4949_PE2 NOISO IPGILVPDLITFGLKAQVVAVASNTSNIIFIYSVIRSFIPNIQQIQLEKSERPKGMCFLT FUGRU16_1_PE12 ENSTRUG00000004936 IPGILVPDIVAFDPRGSTVAVASNTCNMVLVYCITAATMPNIQQISLQTNDRPKGVCFLN FUGRU16_1_PE13 ISOFORMIN IPGILVPDIVAFDPRGSTVAVASNTCNMVLVYCITAATMPNIQQISLQTNDRPKGVCFLN FUGRU16_1_PE14 ISOFORMIN IPGILVPDIVAFDPRGSTVAVASNTCNMVLVYCITAATMPNIQQISLQTNDRPKGVCFLN FUGRU16_1_PE15 ISOFORMIN IPGILVPDIVAFDPRGSTVAVASNTCNMVLVYCITAATMPNIQQISLQTNDRPKGVCFLN GASACGROUPXVIII_14_PE60 ENSGACG00000012380 IPGILVPDIVAFDPRGSTVAVASNTCNMVLVYCITASAMPNIQQISLQANERPKGVCFLN GASACGROUPXVIII_14_PE61 ISOFORMIN IPGILVPDIVAFDPRGSTVAVASNTCNMVLVYCITASAMPNIQQISLQANERPKGVCFLN GORGO2A_26_PE6 NOISO IPGILVPDLIAFNLKAHVVAVASNTCNIILIYSVIPSSVPNIQQIRLENTERPKGICFLT HORSE15_74_PE14 NOISO IPGILVPDLIAFHPKAQVVAVASNTCNIIFIYSVNPSYMPNIQQVQLESSERPKGICFLT HS2_PE405 ENSG00000163026 IPGILVPDLIAFNLKAHVVAVASNTCNIILIYSVIPSSVPNIQQIRLENTERPKGICFLT HS2_PE406 ISOFORMIN IPGILVPDLIAFNLKAHVVAVASNTCNIILIYSVIPSSVPNIQQIRLENTERPKGICFLT LAMPAGS_1066_1_PE3 NOISO IPGILVPDLIAFSLKAQVVAVASNTYNTIFIYSVIPSFMPNIRQIQLESNERPKGICFLT LOXAF20_38_PE7 NOISO IPGILVPDLMAFSLKAQVVAVASSTCNIILIYSVIPSSMPNIQQIQLESNERPKGICFLT MACEUSCAFFOLD41370_PE1 NOISO IPGILVPDLLAFDPKSQVAAVASNTCHIILIYSLSPSLVPEVQCIRLETCERPKGICFLS MACMU13_24_PE8 ISOFORMIN IPGILVPDLIAFNLKAHVVAVASNTCNIILIYSLIPSSVPNIQQIRLENTERPKGICFLT MACMU13_24_PE9 ENSMMUG00000012340 IPGILVPDLIAFNLKAHVVAVASNTCNIILIYSLIPSSVPNIQQIRLENTERPKGICFLT MICMUGS_3671_1_PE4 NOISO IPGILVPDLIAFNLKAQVVAVASNTCNIILIYSVMVCPVPSIQQIHLENTERPKGICFLT MONDO1_764_PE8 ENSMODG00000009400 IPGILVPDLLAFDPKSQVLAVASNTCPTILVYSLTPTLAPGVQCIRLENCERPKGICFLS MONDO1_764_PE9 ISOFORMIN IPGILVPDLLAFDPKSQVLAVASNTCPTILVYSLTPTLAPGVQCIRLENCERPKGICFLS MONDOUN_31_PE18 NOISO IPGILVPDILAYDPKSQVMAVASNTCYTILVYSLIPALAPGVQCIRLENCERPKGICFLS MONDOUN_32_PE1 ENSMODG00000002152 IPGILVPDILAYDPKSQVMAVASNTCHTILVYSLIPALAPGVQCIRLENCERPKGICFLS MONDOUN_32_PE2 ISOFORMIN IPGILVPDILAYDPKSQVMAVASNTCHTILVYSLIPALAPGVQCIRLENCERPKGICFLS MOUSE12_PE46 ISOFORMIN IPGILVPDLIAFNLTAELVAVASNTCNVILIYSAAPSSMPNIQQIQLESNERPKGICFLT MOUSE12_PE47 ENSMUSG00000051721 IPGILVPDLIAFNLTAELVAVASNTCNVILIYSAAPSSMPNIQQIQLESNERPKGICFLT MYOLUGS_4810_PE3 NOISO IPGILVPDLIAFNPKAKVVAVASNTCNIIFIYSVIPAVMPNIQQIQLESGERPKGICFLT ORNAN2_7_PE6 NOISO IPGILVPDIMAFDPKAQVVAIASNTCNVILVYSLTPSSMPNIQQIQLAACERPKGVCFLF ORYLA24_3_PE7 NOISO IPGILVPDIVAFDPRASTVAVASNSCNMVLVYSITASAMPNIQQISLQQNDRPKGVCFLS OTOGA4515_PE3 NOISO IPGILVPDLIACNLKAQVVAVASNTCNIILIYSVILCSAPSFQQIHLENTERPKGLCFLT PANTR2A_26_PE5 ENSPTRG00000011707 IPGILVPDLIAFNPKAHIVAVASNTCNIILIYSVIPSSVPNIQQIRLENTERPKGICFLT PANTR2A_26_PE6 ISOFORMIN IPGILVPDLIAFNPKAHIVAVASNTCNIILIYSVIPSSVPNIQQIRLENTERPKGICFLT PIG3_109_PE13 NOISO IPGILVPDLIAFNLKAQVLAVASNSCNVIFIYSLIPSLMPHIQQIQLENNDRPKGICFLT POEGU3_109_PE6 NOISO IPGILVPDIMAFDSKTQTVSVASNTCNVILVYSLTSSNLPNIQQIQLEKSEKPKGLCFLT POEGU3_110_PE1 NOISO IPGILVPDIMAFDLRAQIVAVASNTSNIVLVYSVTSSSMPHIQQIQLEKNERPKGLCFLT PONPY2A_91_PE8 NOISO IPGILVPDLIAFNLKAHVVAVASNTCNIILIYSVIPSSFPNIQQIRLENTERPKGICFLT PTEVAGS_3150_PE3 NOISO IPGILVPDLIAFNLKAQVVAVASNTCNVIFIYSIIPSFMPNIQKIQLESSERPKGLCFLT RABIT2_177_PE8 NOISO VPGILVPDLIACHPKAQVVAVASNTGNTVLVYSVMSSSMRNVQHIQLESSERPKGLCFLT SORARGS_7136_PE2 NOISO IPGILVPDLIAFSLKAQLVAVASNTYNMIFIYSVVPSFMPNIQKIQLESSERPKGICFLT SPETRGS_4731_PE4 NOISO VPGILVPDLIAFNLKAQVVAVASNTCNIILIYSIISSSMPNIQQIHLESNERPKGICFLA TARSY37049_PE1 NOISO IPGLLVPDLIAFNHKAQVVAVASNTCNIIFVYSVIPSSVPNIQKIQLENTERPKGICFLT TETNG14_PE545 NOISO IPGILVPDIVAFDPRGSTVAVASNTCNMVLVYCIAAAAMPNIQQISLQTNDRPKGVCFLT TUPGBGS_4558_PE2 NOISO IPGILVPDLIAFNLKAQVVAVASNTCNSILIYSVFPSSMPNIQQIQLESSERPKGICFLT TURTRGS_2798_PE3 NOISO IPGILVPDLMAFNLKAQVVAVASNTCNIIFIYSVVPSFMPNIQQIQLESNERPKGICFLT XENTR180_2_PE1 NOISO IPGILVPDILAFDPTAHIVAVASNTCSAVLVYSLTSSSVPNIQQILLEKNERPKGLCFLT MATCH :.*:*.**::: :**.: : :*. .: : * ::***: * CONSENSUS IPGILVPD??AF??????VAVASNTCN????YS??????P?IQQI?LE??ERPKG?CFL?

AILMEGL192369_1_4_PE9 NOISO DKLLLILVGRQKSTESAFLPSSKTDQYIIRLIVREVTLE----EEFPVTATKNQSG--DS ANOCA3_9_PE3 NOISO DKLLLILVGKQKLTDPAFLPSSRSDKYILRLMIKEVVGK----EGSSALSGVTQVC--FT ANOCA3_9_PE4 NOISO DNLLLILIGKQKFTDPALIPSSNSDRYIIRLMIKELSFE----EESSAKSNVPQSL--PF BOVIN11_80_PE9 NOISO DKLLLILVGRQKSMDSAFLPSSKSDQYMIRLIVREVMLK----EDSPVTLSENQSG--NS CALJA14_89_PE17 NOISO DQLLLILVGKQKLSDTTFLPSSKSDQYVLSLTVREVMLE----EESSITSSESQTT--YS CANFA17_22_PE8 ENSCAFG00000003949 DKLLLILVGRQKSTDSAFLPSSKTDQYTIHLIVREVTLE----EELPVTSSENRSG--YS CANFA17_22_PE9 ISOFORMIN DKLLLILVGRQKSTDSAFLPSSKTDQYTIHLIVREVTLE----EELPVTSSENRSG--YS CAVPO18_7_PE5 NOISO DKLLLILVGKPKSTDATFLPCSESDQYVIRLVLQEVVLE-----ESSVTSDDTRSA--GA CHICK3_PE1462 NOISO NKLLLILVGKQKFTDPAFLPSSRSDKYMIRLMIKELIFE----VAPSTSASVNGSC--AS CHICK3_PE1463 ENSGALG00000016499 DKLLLILIGKQKFPEPSLIPSSSSDRYVMRLMIKELMLE----EDATTLPDTKQHM--LY CHICK3_PE1464 ISOFORMIN DKLLLILIGKQKFPEPSLIPSSSSDRYVMRLMIKELMLE----EDATTLPDTKQHM--LY DANRE20_47_PE11 NOISO NKMLLFMIGRQKSNDPAFLPSSNTDKYILRLTAKELVFD----EESTTKSESP------- DASNOGS_5924_PE3 NOISO DRLLLVLVGKQKSTDLTFLPSSKSDPYIIRLTVREVMVA----EESSVTSSESHSG--CS DIPOR7709_PE1 NOISO DTLLLILVGKQKSTDTAFLPSSESNQFFIRLIVKQVVLENVGRDESLVASNESRST--YS ECHTE81750_PE1 NOISO GKLLLILVGMQKPTDVAFLPSSKSDQYIIRLVVREVTLE----EASPGTSSETQSG--DA FELCAGS_4949_PE2 NOISO DKLLLILVGRQKSTDSAFLPSSKTDQYIIRLIVREVTLE----KELPVTSSKNQSG--YS FUGRU16_1_PE12 ENSTRUG00000004936 EKMLLLMVGRQKSNDPVFLQSSNTEKYFLRLFAKELIYE----GEAPVTPSPTARCHEST FUGRU16_1_PE13 ISOFORMIN EKMLLLMVGRQKSNDPVFLQSSNTEKYFLRLFAKELIYE----GEAPVTPSPTARCHEST FUGRU16_1_PE14 ISOFORMIN EKMLLLMVGRQKSNDPVFLQSSNTEKYFLRLFAKELIYE----GEAPVTPSPTARCHEST FUGRU16_1_PE15 ISOFORMIN EKMLLLMVGRQKSNDPVFLQSSNTEKYFLRLFAKELIYE----GEAPVTPSPTARCHEST GASACGROUPXVIII_14_PE60 ENSGACG00000012380 DKTLLLMSDRQKSNEPAFLPSSNTDKYVLRLVAKELMLN----GEIPLTPPPSDHSREPP GASACGROUPXVIII_14_PE61 ISOFORMIN DKTLLLMSDRQKSNEPAFLPSSNTDKYVLRLVAKELMLN----GEIPLTPPPSDHSREPP GORGO2A_26_PE6 NOISO DQLLLILVGKQKLTDTTFLPSSKSDQYAISLIVREIMLE----EEPSITSGESQTT--YS HORSE15_74_PE14 NOISO DKLLLILIGKQKSTDSAFLPSSKSDEYIIHLVVREVMLE----EECPVAPSGNQSG--YS HS2_PE405 ENSG00000163026 DQLLLILVGKQKLTDTTFLPSSKSDQYAISLIVREIMLE----EEPSITSGESQTT--YS HS2_PE406 ISOFORMIN DQLLLILVGKQKLTDTTFLPSSKSDQYAISLIVREIMLE----EEPSITSGESQTT--YS LAMPAGS_1066_1_PE3 NOISO DKLLLILVGEQRPTDSAFLPSSKSDQYMLRLIVREVMLE----EESPVTLSENQSG--YS LOXAF20_38_PE7 NOISO DRLLLILVGTQKSTDTAFLPSSKSDQYIIRLVVREIKLE----EGSLVTSSEGQSG--YS MACEUSCAFFOLD41370_PE1 NOISO DKLLLILVGKQKVTDSTFLPSSKSDRYTIRLVVREVTFE----GEPSWKSAWSQQD--FC MACMU13_24_PE8 ISOFORMIN DKLLLILVGKQKLTDTTFLPSSKSDQYAISLIVREVMLE----EEPSITSSESHTT--YS MACMU13_24_PE9 ENSMMUG00000012340 DKLLLILVGKQKLTDTTFLPSSKSDQYAISLIVREVMLE----EEPSITSSESHTT--YS MICMUGS_3671_1_PE4 NOISO DKLLLILVGKRKFIDTAFPPSSKSDQYDIHLIVKEVMLE----EEPSATSNERQSA--YS MONDO1_764_PE8 ENSMODG00000009400 DKMLLILVGKQKFTDPTFLPSSKSDRYTIRLMVKEVNFG----DEPSIKFVWSQQD--FY MONDO1_764_PE9 ISOFORMIN DKMLLILVGKQKFTDPTFLPSSKSDRYTIRLMVKEVNFG----DEPSIKFVWSQQD--FY MONDOUN_31_PE18 NOISO DKRLLISVGKQKFTDPTFLPSSKSEMYNIHLEVKEVDFG----KEPSMTSVWSQRD--FC MONDOUN_32_PE1 ENSMODG00000002152 DKRLLISVGKQKFMDPTFLPSSKSEMYNIHLEVKEVDFG----KEPSMTSVWSQRD--FC MONDOUN_32_PE2 ISOFORMIN DKRLLISVGKQKFMDPTFLPSSKSEMYNIHLEVKEVDFG----KEPSMTSVWSQRD--FC MOUSE12_PE46 ISOFORMIN DRLLLIAVGKQKPSEAAFLPSSEYGQYTVRLIVREMAQG----SESSGTSAESQGA--YS MOUSE12_PE47 ENSMUSG00000051721 DRLLLIAVGKQKPSEAAFLPSSEYGQYTVRLIVREMAQG----SESSGTSAESQGA--YS MYOLUGS_4810_PE3 NOISO DKLLLILIGKQKSTDSTFLPSSKSDEYVIRLTVREVTLK----EEFPVTVSENQSG--YT ORNAN2_7_PE6 NOISO NSLLLILVGKQKSTEPAFLPSSKSDKFSLHLMVKEILLE----EEDSSVSSGSSPSDSPS ORYLA24_3_PE7 NOISO DKVLLLMVGRQKSNDPAFLPSSNTDKYILRI-AKELMNE----GGRAMTPSSPAHNNEPS OTOGA4515_PE3 NOISO DKLLLILVGKQKSADSAFLSSSMFDQYVLHLIVKEVTLE----KQSSVTSNESQSG--CS PANTR2A_26_PE5 ENSPTRG00000011707 DQLLLILVGKKKLTDTTFLPSSKSDQYAISLIVREIMLE----EEPSITSGESQTT--YS PANTR2A_26_PE6 ISOFORMIN DQLLLILVGKKKLTDTTFLPSSKSDQYAISLIVREIMLE----EEPSITSGESQTT--YS PIG3_109_PE13 NOISO DKLLLILIGKQKSTDSAFPPSTKSDQYIIRLIIRDITLE----KESPVTPSENQSG--YS POEGU3_109_PE6 NOISO NKLLLILVGKQKFTDPAFLPSSRSDKYMIRLMIKELILE----MGPSKLVSADGS----- POEGU3_110_PE1 NOISO DKLLLILIGKQRFPDPNLIPSSSSDRYVIRLMVKELMLE----ENSSAFPETKQKM--FY PONPY2A_91_PE8 NOISO DQLLLILVGKQKLTDTTFLPSSKSDQYAISLIVREIMLE----EEPSITSSESQTT--YS PTEVAGS_3150_PE3 NOISO DKLLLILVGKQKSTDSTFLPSSKSDEYVIRLIVREIMLE----EECPVTPSENQSG--YS RABIT2_177_PE8 NOISO DRLLLILVGKPSCTDVAFLPSSESAQYAIHLTVREVTVG----EPSSATSTESRSA--CS SORARGS_7136_PE2 NOISO DKLLLILVGKPNAADSTFLPSSKSEQYVFRLVVREVTLE-----EFSDALSESQTS--NM SPETRGS_4731_PE4 NOISO DKL-LILVGKQKSTDSAFLPSSESDQYILHLIVREVLLK----EESSATSNKSQSA--PS TARSY37049_PE1 NOISO DKLLLILVGKQKCTDTTFIPSSKSDQYVIRVIVREVMLE----EESSVTSNESQST--YS TETNG14_PE545 NOISO EKTLLLMVGRQKSGDPVFLQSSNTEKYILRLFAKELMHD----GEAP--PSPSARSHESA TUPGBGS_4558_PE2 NOISO DKLLLILVGKQKSADTAFLPSSETEQYVIRLIVREVMLE----EESSIMLDESQSA--YP TURTRGS_2798_PE3 NOISO DKLLLILIGKQKSTDSAFLLSSKSDQYMIRLIVREVMLE----EGSPVTPSENQSG--HS XENTR180_2_PE1 NOISO DKMLLVLVGRQKTSDPAFLPSSSSDKYLIRLMVKEVMFD----EDSSASSGGNTSV--QA MATCH *. . : : .: : . : ::: CONSENSUS D??LLI?VG?QK??D??FLPSS????Y???L???E?????????????????????????

AILMEGL192369_1_4_PE9 NOISO TLSTLLNKTDRKKRTESPSPDF--DHQNRGLL-TANGSRQSGRAGRTLIREIKSPP---- ANOCA3_9_PE3 NOISO NV-P---V--KRETIETHSSDT--HPLKDGLLLPGCNVPQSPKNRRKLIEEIKSTSTDQS ANOCA3_9_PE4 NOISO SVESSVNLSGKRKYFDNLAAEN--HVVGRELLIPGSTIIQSSSGRRRMLEELKSPTL--- BOVIN11_80_PE9 NOISO AFSTLINKTNIKKLIEDLSPDF--CHQSTGLLFTANSSSQSGQPGRTLIKEIESPA---- CALJA14_89_PE17 NOISO TCSALLNKANRKKLIESLSPDF--CYQNKGLLPTANASSQNGRPGRTLIKEIQSPL---- CANFA17_22_PE8 ENSCAFG00000003949 TFSTLLNKTDRKKLIESLSPDF--CYQNRGLL-TAKGSRQSGKPERTLIKEIKSPP---- CANFA17_22_PE9 ISOFORMIN TFSTLLNKTDRKKLIESLSPDF--CYQNRGLL-TAKGSRQSGKPERTLIKEIKSPP---- CAVPO18_7_PE5 NOISO PLSGHLNKANGKKRIENLSPGV--GCQNRVLLLTADTSSLSAKPGRTLIEEVKSLP---- CHICK3_PE1462 NOISO VN-G---SLNLSNIPHDVSTDV--HPLSRGLLIPDRAALQSPTSRRKLIEEIKSPGYEQS CHICK3_PE1463 ENSGALG00000016499 NFVSSVNIPGKRKFFENLATED--QHQSRDLLIPRSTVIQSPSGRRRLIEEVKSPSYEQS CHICK3_PE1464 ISOFORMIN NFVSSVNIPGKRKFFENLATED--QHQSRDLLIPRSTVIQSPSGRRRLIEEVKSPSYEQS DANRE20_47_PE11 NOISO -S----QHHGIRRHSENFTKEDR--LSIKDLILPGGSVIVSPSSRRKLIEEVRSS--DLS DASNOGS_5924_PE3 NOISO PFSALLNKAIRKKLTASLSPDF--GHQNRGLLLTVGTSSQSGSLGRALVKEIQSPT---- DIPOR7709_PE1 NOISO AFSALFNKARREMLSNNLSPDV--CHQNREPLFTADASYQKARPGRALGREITSPP---- ECHTE81750_PE1 NOISO PFSALLSKTNQRKAMESLCPDF--CHQNRELFLTARTRSQSGSPGRTLIQEIRSPPP--- FELCAGS_4949_PE2 NOISO TFSTPLSKIDRKKLLESLSPDL--CHQNRGLF-TSDSRSQCERPGRTLIEEIRSPP---- FUGRU16_1_PE12 ENSTRUG00000004936 SK----FSPRIRRHSEHLSKEDREHPGIRDLVLPGGVVIRSPGNRRRLVEEVRSC--EAS FUGRU16_1_PE13 ISOFORMIN SK----FSPRIRRHSEHLSKEDREHPGIRDLVLPGGVVIRSPGNRRRLVEEVRSC--EAS FUGRU16_1_PE14 ISOFORMIN SK----FSPRIRRHSEHLSKEDREHPGIRDLVLPGGVVIRSPGNRRRLVEEVRSC--EAS FUGRU16_1_PE15 ISOFORMIN SK----FSPRIRRHSEHLSKEDREHPGIRDLVLPGGVVIRSPGNRRRLVEEVRSC--EAS GASACGROUPXVIII_14_PE60 ENSGACG00000012380 SN----FGLRIRRHSEHQPKDDREHQGIKDLVLPGGGVVRSGANRRRLVEEVRSG--ELS GASACGROUPXVIII_14_PE61 ISOFORMIN SN----FGLRIRRHSEHQPKDDREHQGIKDLVLPGGGVVRSGANRRRLVEEVRSG--ELS GORGO2A_26_PE6 NOISO TFSAPLNKANRKKLIESLSPDF--CHQDKGLLLTVNTSSQNGRPGRTLIKEIQSPL---- HORSE15_74_PE14 NOISO AFSTLLNKADRKKLLESLSPDF--CHQTRGLLLTANGSRQSGRPGGSLVKGIRTPP---- HS2_PE405 ENSG00000163026 TFSAPLNKANRKKLIESLSPDF--CHQNKGLLLTVNTSSQNGRPGRTLIKEIQSPL---- HS2_PE406 ISOFORMIN TFSAPLNKANRKKLIESLSPDF--CHQNKGLLLTVNTSSQNGRPGRTLIKEIQSPL---- LAMPAGS_1066_1_PE3 NOISO ALSTVLNQAN-KKLIESLSPDF--YHQNGGLLLTANSSNPSRNPGRTLIKEIKSPP---- LOXAF20_38_PE7 NOISO TFSSLLNKANRRKLIESLSPDF--HHQNTGLLLRASTSSQSGSPGRTLIKETKSPL---- MACEUSCAFFOLD41370_PE1 NOISO NTSMMLGMDSKKDPGEHPCPIS--YPQMRELLIPGDLTMQSLASGKPDRTVAPQVLSPS- MACMU13_24_PE8 ISOFORMIN TFSAPLNKANRKKLIESLSPDF--CHQNKGLLLTANTSSQTGRPGRTLIKEIQSPL---- MACMU13_24_PE9 ENSMMUG00000012340 TFSAPLNKANRKKLIESLSPDF--CHQNKGLLLTANTSSQTGRPGRTLIKEIQSPL---- MICMUGS_3671_1_PE4 NOISO TFRAPLNKADRKQLIEGLSPDF--CYQNTGLFLTANTSSQSGSPGGKLIEEIQRPL---- MONDO1_764_PE8 ENSMODG00000009400 NDSPALGLANQRKPGESLCLNT--CPQKKDLLMPPRIQ--SLPQGKSLIED----ITGA- MONDO1_764_PE9 ISOFORMIN NDSPALGLANQRKPGESLCLNT--CPQKKDLLMPPRIQ--SLPQGKSLIED----ITGA- MONDOUN_31_PE18 NOISO NLSLGLGMANKRKPGDSLCLNT--YPQKRDLLMPGRIQ--SLPRGKPSTSQ----LGKP- MONDOUN_32_PE1 ENSMODG00000002152 NLSLGLGMANKRKPGDSLCLNT--YPQKRDLLMPGRIQ--SLPRGKSLIED----ITGA- MONDOUN_32_PE2 ISOFORMIN NLSLGLGMANKRKPGDSLCLNT--YPQKRDLLMPGRIQ--SLPRGKSLIED----ITGA- MOUSE12_PE46 ISOFORMIN DFTALLSKADREKFTDSLSPGS--SPLSQGLLLTPNSSTQSGRSGRALIQEIKSPL---- MOUSE12_PE47 ENSMUSG00000051721 DFTALLSKADREKFTDSLSPGS--SPLSQGLLLTPNSSTQSGRSGRALIQEIKSPL---- MYOLUGS_4810_PE3 NOISO TLSALLNKAERKKPIESLSPDI--CHQNRGLLLTANSSSQGGRPGSTFIKEIKRPP---- ORNAN2_7_PE6 NOISO AGDDVLDVAGPGKSPENLPPAS--FLKGEKLLIPGSDTP--FLGGKPLIEEVKSPASEIS ORYLA24_3_PE7 NOISO SN----FCAGIRRHSEHLPKDDRERPGIKDLVLPGRGVVCSPGNRRRLVEEVRSS--EAS OTOGA4515_PE3 NOISO TSSALLNKANRIKLIENLSPGF--GYSNRGLLSTANTSSQSGKHGRRLIEEIQSPP---- PANTR2A_26_PE5 ENSPTRG00000011707 TFSAPLNKANRKKLIESLSPDF--CHQNKGLLLTVNTSSQNGRPARTLIKEIRSPL---- PANTR2A_26_PE6 ISOFORMIN TFSAPLNKANRKKLIESLSPDF--CHQNKGLLLTVNTSSQNGRPARTLIKEIRSPL---- PIG3_109_PE13 NOISO AFNTPLNKANREKLLESLSSAF--YQQNRELLLTTNIGNQSGRPGRTLIKEIKSPP---- POEGU3_109_PE6 NOISO ---S---SLNLSNVTHDPSRGV--HPLSRGLLIPDRSALQSPTSRRKLIEEIKSPVCEQN POEGU3_110_PE1 NOISO NFESSVNIPGKRKFFENLATED--QPQSRELLIPRSTVIQSPSGRRRLIEEVKSPSYEQS PONPY2A_91_PE8 NOISO TFSAPLNKANRKKLIESLSPDF--CHQNKGLLLTVNTSSQNGRPRRTLIKEIQSPL---- PTEVAGS_3150_PE3 NOISO TFSTLLNKAERKTLIESLSPDI--CYQNRGFLFTTNSSGRSGRPGSALIKEIKSPP---- RABIT2_177_PE8 NOISO TFSALLEKADRKLVIESPSPNV--CPQRGGLLLTGNTSSRSGGPRKALIKEIRSPL---- SORARGS_7136_PE2 NOISO L----FETADGR--KPSRPPDF--CHQNRELLLTADPS---RKPGSTLIREIKSPP---- SPETRGS_4731_PE4 NOISO ICSALL---NRKKLIRSLSPDF--CHQNRGLLLTANTNSQNKRPGRPLIKEIKSLP---- TARSY37049_PE1 NOISO TFSALLSKANGDKLIESLSPGF--GHQNRGLLLSANTSSHNGRPGRILIKEIQSPL---- TETNG14_PE545 NOISO SN----FSPRIRRHSEHLSKDEREHPGIKDLVLPGAAVIRSPGNRRRLVEEVRSC--EAS TUPGBGS_4558_PE2 NOISO PFSVLLNKMNRKKLPKSFSPDF--CHQNKGFLLTANTGSQNERPGRTMIKEIKSPP---- TURTRGS_2798_PE3 NOISO AFSTLLNKANRKKLIESLSPDF--CHQNGGILLTANSSSQSGRPGRTLIQEIRSPP---- XENTR180_2_PE1 NOISO SFDSSMSIQDKKKLVESLYKEG--QSAHREILLPGGVAPPTYLRKKKLIEEIRSYDGDQS MATCH . CONSENSUS ?????????????????L????????????L????????????????L??E??S??????

AILMEGL192369_1_4_PE9 NOISO -------------TSVCAGSIVLDGLDAKPINCSVTCP------RSSSTPPH-----TLT ANOCA3_9_PE3 NOISO LSMNRVDSKEKKLP--KDFPQALEALDMEPANRSLVLQGPESSSGVSNVPISQNKPLHSP ANOCA3_9_PE4 NOISO ----------------ADPTIALETLDTEPVNRSVALFGLGTSARFSHR---------SI BOVIN11_80_PE9 NOISO -------------SSICDGSTFLETLDARPVNLSVTPP------RPSGTPAH-----TST CALJA14_89_PE17 NOISO -------------SSICDGSIALDA---EPVIQPATLP------RHSSTPDH-----TSP CANFA17_22_PE8 ENSCAFG00000003949 -------------TSVCDGFITLKTLDAEPVNGSVSLP------RSRSTPNH-----TLS CANFA17_22_PE9 ISOFORMIN -------------TSVCDGFITLKTLDAEPVNGSVSLP------RSRSTPNH-----TLS CAVPO18_7_PE5 NOISO -------------ASSLHGSVALETLHRPSR-AQAARP------G-----------LPSM CHICK3_PE1462 NOISO CLLNMSDLKEKKVS--LNFPPAVESLNAEPLNQSASLSTTS--LAFSNKPTSPKRQIETA CHICK3_PE1463 ENSGALG00000016499 SSSSVSDLDEKKLP--GDPSVALETLDAEPINRSMALLGFGTASRLSSRPASPKVQFNVI CHICK3_PE1464 ISOFORMIN SSSSVSDL----------------------------------ASRLSSRPASPKVQFNVI DANRE20_47_PE11 NOISO PVASSADFSDRASSA---SSVTLENYDMDHITRMASLAVAGQASRDSSRPCSPRYETSEK DASNOGS_5924_PE3 NOISO -------------SSTCGDSVAPETPDAKPFNWSEPLP------RPS-----------ST DIPOR7709_PE1 NOISO -------------STASEDPSVLD----TPVLLWATLS------RPSRLSDH-----ASM ECHTE81750_PE1 NOISO -------------SSLHEGSVALDTLDAEPVSRSLAKP------RPGGSPGL-----TST FELCAGS_4949_PE2 NOISO -------------SSICDGSIALRTLDAEPVNRSVTPP------RSSSTPDH-----TST FUGRU16_1_PE12 ENSTRUG00000004936 PVTSSVDFFDQAPSSAS--SVTAENFDMDHVSRLTSLTVANQPSRDSSRASSPRPELLDK FUGRU16_1_PE13 ISOFORMIN PVTSSVDFFDQAPSSAS--SVTAENFDMDHVSRLTSLTVANQPSRDSSRASSPRPELL-- FUGRU16_1_PE14 ISOFORMIN PVTSSVDFFDQAPSSAS--SVTAENFDMDHVSRLT------------------------- FUGRU16_1_PE15 ISOFORMIN PVTSSVDFFDQAPSSAS--SVTAENFDMDH------------------------------ GASACGROUPXVIII_14_PE60 ENSGACG00000012380 PVTSSVDFSDRALSSPS--SVAVETFDMDHVNRMTCLAVAGQASRESSRAGSPRHEPSDK GASACGROUPXVIII_14_PE61 ISOFORMIN PVTSSVDFSDRALSSPS--SVAVETFDMDHVNRMTCLAVAGQASRESSRAGSPRHEPSDK GORGO2A_26_PE6 NOISO -------------SSICDGSIALDA---EPVTQPASLP------RHSSTPDH-----TST HORSE15_74_PE14 NOISO -------------SSVCGSSIALETLGAEPVNWSVTLP------RPSSTPEH-----TST HS2_PE405 ENSG00000163026 -------------SSICDGSIALDA---EPVTQPASLP------RHSSTPDH-----TST HS2_PE406 ISOFORMIN -------------SSICDGSIALDA---EPVTQPASLP------RHSSTPDH-----TST LAMPAGS_1066_1_PE3 NOISO -------------SSICDGSTALEAPGAGPVNQPVTLP------RPSGTPDH-----TKT LOXAF20_38_PE7 NOISO -------------SSICEGSIALESLDAEPVNRSASKP------WLSSAPESSAAQFNHS MACEUSCAFFOLD41370_PE1 NOISO -------------PSTSATTVSLEGLEAASGSQSPAQL------SSEARPS---TQDITA MACMU13_24_PE8 ISOFORMIN -------------SSICDDSIALDA---EPVTQPASLP------RHSSTPDH-----IST MACMU13_24_PE9 ENSMMUG00000012340 -------------SSICDDSIALDA---EPVTQPASLP------RHSSTPDH-----IST MICMUGS_3671_1_PE4 NOISO -------------SSICDGPIAPETLDTKPVSQSETLP------KHNSTPDH-----TST MONDO1_764_PE8 ENSMODG00000009400 -------------SGRQSPR---------PNTTQLSKP------NPNARPSLPMTQCSPI MONDO1_764_PE9 ISOFORMIN -------------SGRQSPR---------PNTTQLSKP------NPNARPSLPMTQCSPI MONDOUN_31_PE18 NOISO -------------KLSPSTVVSMEGLEAMSSSRSSACL------LSNVRPSLPMTQCSLI MONDOUN_32_PE1 ENSMODG00000002152 --------------------------SGAQSSRPSTSQ------LG-KPKLSPSTVCSLI MONDOUN_32_PE2 ISOFORMIN --------------------------SGAQSSRPSTSQ------LG-KPKLSPSTVCSLI MOUSE12_PE46 ISOFORMIN -------------SPLSSDSVVHETLH-RPPWLCPALP------RPSRTPEH-----TST MOUSE12_PE47 ENSMUSG00000051721 -------------SPLSSDSVVHETLH-RPPWLCPALP------RPSRTPEH-----TST MYOLUGS_4810_PE3 NOISO -------------SSVCDDSIALETREAEPVDGSATLP------KTSSTPDF-----TST ORNAN2_7_PE6 NOISO S----------------ERLMDLETLEVEPVSRSAATRR---SLKESNTPAFPKVQVNTQ ORYLA24_3_PE7 NOISO PVTSSVDFSDRPDRAPSSASFAVDSFDMDPVNHMASLAVAGQASRDSSRASSPRFEPPDK OTOGA4515_PE3 NOISO -------------SSICDGSIDLETVGAQPRNQPATLP------QHSSTPDH-----TST PANTR2A_26_PE5 ENSPTRG00000011707 -------------SSICDGSIALDA---EPVTQPASLP------RHSSTPDH-----TST PANTR2A_26_PE6 ISOFORMIN -------------SSICDGSIALDA---EPVTQPASLP------RHSSTPDH-----TST PIG3_109_PE13 NOISO -------------SRICDGATALERVGAGPVTQSGALP------RPSSTPDP-----TST POEGU3_109_PE6 NOISO LVLNISDFKDKKIS--MNFPPAVETLDAEPVNRSVALSN------AWNKPTSPKRQHEAA POEGU3_110_PE1 NOISO SSSSVSDLDEKRLP--GDSLVALETLDAEPMNRSVSLRGCGSPSRISSRPTSPKVQFNVI PONPY2A_91_PE8 NOISO -------------SSICDGSIALDA---EPVTQPASLP------RHSSTPDH-----TST PTEVAGS_3150_PE3 NOISO -------------SSVRNCPIALETQDAAPVNQSVTLP------TPSSRPDL-----TST RABIT2_177_PE8 NOISO -------------SSTGDGSVALEMLH-RPAWAWATEP------RPSRAPDG-----TST SORARGS_7136_PE2 NOISO -------------AGICDDSAVLETLDANPNNHSGTLP------RATSTPDP-----ISP SPETRGS_4731_PE4 NOISO -------------SSITDDSIALET-----------LS------RPSRTPDH-----SST TARSY37049_PE1 NOISO -------------SSIYEGSIAPETPIAAPADRSASVP------RHSSTPDH-----TST TETNG14_PE545 NOISO PVASSVDFSERAPSSAS--SVTVENFDMD------------QPSRDSSRANSPRPEPPDK TUPGBGS_4558_PE2 NOISO -------------SSSCDGSTATNTSAWL-------GL------GNSRTPDD-----TST TURTRGS_2798_PE3 NOISO -------------SSICDGSTALETLDAGPVNQSVTLP------GPSGTPDH-----NST XENTR180_2_PE1 NOISO PTSSANEFDDKRS------KLRVESLDTEPKNRSITLG-LDMDKKPNSRPTSPKSECQK- MATCH CONSENSUS ????????????????????????????????????????????????????????????

AILMEGL192369_1_4_PE9 NOISO PE----PPDWPPS-QNLQREKEIYQL-SKEMEILSRTLTEVQRCLSELTDVLQK----E- ANOCA3_9_PE3 NOISO HE----ISNASKT-NLLRNDKEASYI-SKNLERLCSSFAELQHQLFEVTELLKS----GK ANOCA3_9_PE4 NOISO QE----TLNSPKN-NILASEKGACQI-SRNLERLCGNFNDLQLRLLEITEFSKN----GN BOVIN11_80_PE9 NOISO AE----PPN-------LEREKETYQL-SKELEVVSRNLSEVQRHLSELSDFLHN----GR CALJA14_89_PE17 NOISO LE----PPCLPQG-KNLQSEKETYEL-SKEVEILSRNLVEMQRCLSELKNCLHN----GR CANFA17_22_PE8 ENSCAFG00000003949 PE----PPNLLPR-KNLPREKEIYQL-SKEMEILSRTLTEVQRCLSELTDALHR----E- CANFA17_22_PE9 ISOFORMIN PE----PPNLLPR-KNLPREKEIYQL-SKEMEILSRTLTEVQRCLSELTDALHR----E- CAVPO18_7_PE5 NOISO PE----TLSVHQR-ESLEK--EASRL-TEGLEMLSRNVTEIQQCLFELRDFLYN----RK CHICK3_PE1462 NOISO SK----IPNSYKN--NLLSEKEASYF-SKNVEKLSGNFTQLQHHVCELTELLKA----GK CHICK3_PE1463 ENSGALG00000016499 EE----TSSSPKN-NNLPSERGMSHI-SRNLERLCGSFNDLQLSLSEITDFAKN----GR CHICK3_PE1464 ISOFORMIN EE----TSSSPKN-NNLPSERGMSHI-SRNLERLCGSFNDLQLSLSEITDFAKN----GR DANRE20_47_PE11 NOISO LYSDATPP-------KNSKEKNLEQL-TQNMERIFTRFAEVQQCLSEIREFTQN----GK DASNOGS_5924_PE3 NOISO AE----PPNLPQR-KNLQKAKEVYQL-SKELKTLSRNLVEMQQRLSELKVFLHR----GK DIPOR7709_PE1 NOISO PA----PPHVPPK-ENLQKEKETHQL-AKELEILSRRLTEMQQYIFELMDFVHEHMNTKK ECHTE81750_PE1 NOISO PE----PPNLPQR-TNLGKEKEAYQMLFKKLEVLSRSLSEMQQNLYELTSCLHH----GK FELCAGS_4949_PE2 NOISO PE----PPNLPQS-KNSQKEKETYRL-SKEMEILSRTLTEVQRCLSELTDALHN----GK FUGRU16_1_PE12 ENSTRUG00000004936 FHAENTLPLHEKT-PSAAKEQALEQL-GRNMERLFTRFADVQQCLNEIKDYAQN----GK FUGRU16_1_PE13 ISOFORMIN ---ENTLPLHEKT-PSAAKEQALEQL-GRNMERLFTRFADVQQCLNEIKDYAQN----GK FUGRU16_1_PE14 ISOFORMIN ---KNTLPLHEKT-PSAAKEQALEQL-GRNMERLFTRFADVQQCLNEIKDYAQN----GK FUGRU16_1_PE15 ISOFORMIN ---------HEKT-PSAAKEQALEQL-GRNMERLFTRFADVQQCLNEIKDYAQN----GK GASACGROUPXVIII_14_PE60 ENSGACG00000012380 LHTDPTLPFPEKA-AGPAKERALEQL-GHNMERLFARFADVQQCLAEIRDYNQN----GR GASACGROUPXVIII_14_PE61 ISOFORMIN LHTDPTLPFPEKA-AGPAKERALEQL-GHNMERLFARFADVQQCLAEIRDYNQN----GR GORGO2A_26_PE6 NOISO LE----PPRLPQR-RNLQSEKETYQL-SKEVEILSRNLVEMRRCLSELTNRLHN----GK HORSE15_74_PE14 NOISO PD----PPHPPQR-RNLSKDKETYQL-SEELEILSRKLIEVQRCLSELTDFLHN----GK HS2_PE405 ENSG00000163026 LE----PPRLPQR-KNLQSEKETYQL-SKEVEILSRNLVEMQRCLSELTNRLHN----GK HS2_PE406 ISOFORMIN LE----PPRLPQR-KNLQSEKETYQL-SKEVEILSRNLVEMQRCLSELTNRLHN----GK LAMPAGS_1066_1_PE3 NOISO PE----PPN-------VQREKEIYQL-SKELKVLSRNLNEVQQCLSKLTDSLQN----GK LOXAF20_38_PE7 NOISO QE----PPYMPQR-KNLQREKEAYLI-SKKLEVLSRNLTEMQRCLSELMNCLHN----GK MACEUSCAFFOLD41370_PE1 NOISO HE----PLRFPQG-QCP--EKEESQL-CGTLERLCESFEGLHQRLSELIDLLQG----QP MACMU13_24_PE8 ISOFORMIN LE----PPHLPQR-KSLQSEKETYKL-SKEVEILSRNLVEMQRCFSELTNCLHN----GR MACMU13_24_PE9 ENSMMUG00000012340 LE----PPHLPQR-KSLQSEKETYKL-SKEVEILSRNLVEMQRCFSELTNCLHN----GR MICMUGS_3671_1_PE4 NOISO LE----PTSLSQR-QNLQREKETSQL-PKEVEILSRKLTEMQQCLSELTHFLHS----GK MONDO1_764_PE8 ENSMODG00000009400 CE----PLNLPQG-KGARNEEEEGRL-CETLERLSGSLLDLQKCLSELIDLLHG----KK MONDO1_764_PE9 ISOFORMIN CE----PLNLPQG-KGARNEEEEGRL-CETLERLSGSLLDLQKCLSELIDLLHG----KK MONDOUN_31_PE18 NOISO RE----PLSLPQV-KVSKNEEGESQL-CGTLERLSGSFADLQQRLSQLIDLLLE----KK MONDOUN_32_PE1 ENSMODG00000002152 RE----PLSLPQV-KVSKNEEGESQL-CGTLERLSGSFADLQQRLSQLIDLLLE----KK MONDOUN_32_PE2 ISOFORMIN RE----PLSLPQV-KVSKNEEGESQL-CGTLERLSGSFADLQQRLSQLIDLLLE----KK MOUSE12_PE46 ISOFORMIN PE-----LNSPQR-ENLQKEKETCPL-SRELEILSRHLVAMQQYLSELTGFLHK----EK MOUSE12_PE47 ENSMUSG00000051721 PE-----LNSPQR-ENLQKEKETCPL-SRELEILSRHLVAMQQYLSELTGFLHK----EK MYOLUGS_4810_PE3 NOISO LG----PLNLPPR-KNLQREKEACQL-SKELEILSRKLMEVQRSLSELTDFLRN----GK ORNAN2_7_PE6 NOISO ES----L-RPPKS--N--LPKKASRL-LKDLERLYGSFSELQQRLAQLPDLKQN----GK ORYLA24_3_PE7 NOISO RQTEPAPPLPEKAAANPARERGLDQL-VLNMERLFTRFADVQQCLTDIRKYKQL----IT OTOGA4515_PE3 NOISO LE----PTNLSQW-NNLQGEKETSYL-TKEVENLSRNLTEMQQCLSELTDFLHN----GK PANTR2A_26_PE5 ENSPTRG00000011707 LE----PPRLPQR-KNLQSEKETYQL-SKEVEILSRNLVEMQRCLSELTNRLHN----GK PANTR2A_26_PE6 ISOFORMIN LE----PPRLPQR-KNLQSEKETYQL-SKEVEILSRNLVEMQRCLSELTNRLHN----GK PIG3_109_PE13 NOISO ME----PPT-------LQGEKESYQL-SKELEVLSRTLIEVHRRLSELTDFLRN----GK POEGU3_109_PE6 NOISO SK----IPNSYKN--NLFNEKEASYF-LKNVEKLSGNFTELQHHISELTELLKS----GK POEGU3_110_PE1 NOISO QE----ASNYPKN-SNLPSERGMSHI-SRNLERLCGSFNELQLSLSEISDLARN----GR PONPY2A_91_PE8 NOISO LE----PPRLPQR-KNLQSEKETYQL-SKEVEILSRNLVEMQRCLSEL-NRLHN----GK PTEVAGS_3150_PE3 NOISO PG----PPNFLQR-NNLEREKETCQL-AKELEVLSKNLTEVQRCLSKLTDFLYN----GK RABIT2_177_PE8 NOISO PE----TPEVPSK-KNLEREKGTEQL-CKELESLSRKLTEMQRSLSELTDFVQN----GK SORARGS_7136_PE2 NOISO PE----PPDLPPV-KTVQ---DPWQL-SREMDALSWKLTQVQQCLSELAGSLLN----GK SPETRGS_4731_PE4 NOISO PK----PPYGFQK-ENLQKEKETYQL-PKELGILSRNLIELQQCLSELMDFVHN----GK TARSY37049_PE1 NOISO PR----PPDLPQG-KNLQRRKNTYLL-SEEVEILSRNMSEMQRCVSQLKDFLHN----GK TETNG14_PE545 NOISO FHTEATLPLAEKT-QGPGKERALEQL-GHNMERLFTRFADVQQCLHEIKDYTQN----GK TUPGBGS_4558_PE2 NOISO ME----PPHLPQR-RNLQGEKETYQL-SKELEILSKNLIEMQQRLSELTDFLHN----EK TURTRGS_2798_PE3 NOISO AG----PPN-------LQVENENYQL-SKILEILSRNLIEVQQRLSELTDFLHN----GK XENTR180_2_PE1 NOISO SS----PPNFIKH-GEMSPQQEILSI-SRNVERLCCNFAHLQQHLSELTDITRN----GK MATCH : : : . :: . .: CONSENSUS ???????????????????E?????L?????E?L???????Q??L?E?????????????

AILMEGL192369_1_4_PE9 NOISO KSS--PMYPLFQDPPYVHIAYQKSYYVGPV-VEKRAVLLCNGKLRLSTVQQTFGLSLVEM ANOCA3_9_PE3 NOISO KTV--PRYPSSRDPSFVNIIYQKESSG-TVTPEKRAVILCDGKLRLSVIQQIFNLVLIEM ANOCA3_9_PE4 NOISO KLS--VAYPSSQEPPFVHITYQKLYSNGSIIEETKTVLLCDGKIHLSLVQQLFDLPVVEM BOVIN11_80_PE9 NOISO KSS--PVYPLSQDLPYVHITCQKSHFVHPV-VEKRMMLLCNGKLRLSTVQQTFGLSLVEM CALJA14_89_PE17 NOISO KSS--SVYPLSQDPPYVHIVCQKPYYLGPV-VEKRAVLLCDGKLRLSTVEQTFGLSLIEM CANFA17_22_PE8 ENSCAFG00000003949 KSS--PVYPPSQDLPYVHITYQKSYNVGPG-VEKRAILLCNGKLRLSTVQQTFGLSLIEM CANFA17_22_PE9 ISOFORMIN KSS--PVYPPSQDLPYVHITYQTHTGSFSV-LIAKA------SSH--------------- CAVPO18_7_PE5 NOISO KSS--PVYPLSEDPPYVHIIYQKPYCAGPV--EKRAVLLCSGKLRLGVIQQLFGLSLVEM CHICK3_PE1462 NOISO RNL--PMYPSSQEPSFINITCQKQLSR-NDSDERRSVILCEGKLRLSVVQQIFNLSLVEM CHICK3_PE1463 ENSGALG00000016499 RVS--LAYPSSQEPPVIHITYQKNFSNGAVTEETKDVLLCDGKIHLNLVQQLFDLSIIEM CHICK3_PE1464 ISOFORMIN RVS--LAYPSSQEPPVIHITYQVCVSFAQLLSKTV--LHS-------------------- DANRE20_47_PE11 NOISO KIA--CSYPSAYEPQYVHITCQKQLSENVYTDERRPLLLCGGRICLRVVQELFGLTVVEM DASNOGS_5924_PE3 NOISO TSF--PGYPRSQEPPYVHITCQRPCH--PA-VEKRVVLLCDSKLRLSTVQQTFGLFLIEM DIPOR7709_PE1 NOISO KSS--PVYPLSQDPPYVYIICQKPCFIGPA--EKRDVLLCNGKLRLSAVQQLFGLSLVEM ECHTE81750_PE1 NOISO KPP--AGYPRSQDPPYVHIVCQKPYSVGAV-VERRAMLLCHGKLRLSVLQQTFDLSLIEM FELCAGS_4949_PE2 NOISO KSS--PVYPLSRDLPYVHITYQKSHYVGPV-VEKRAVLLCNGKLRLSTVQQTFGLSLIEM FUGRU16_1_PE12 ENSTRUG00000004936 KAQ--AAYPSASEPPYVNVTCQKQLSENVFIDERRPVLLCDGKLCLRALQDLFNLTVVEM FUGRU16_1_PE13 ISOFORMIN KAQ--AAYPSASEPPYVNVTCQKQLSENVFIDERRPVLLCDGKLCLRALQDLFNLTVVEM FUGRU16_1_PE14 ISOFORMIN KAQ--AAYPSASEPPYVNVTCQVPCGLYWWRIQ--------TGLCLSR------------ FUGRU16_1_PE15 ISOFORMIN KAQ--AAYPSASEPPYVNVTCQKQLSENVFIDERRPVLLCDGKLCLRALQDLFNLTVVEM GASACGROUPXVIII_14_PE60 ENSGACG00000012380 KAP--GVYPAASEPPYVNVTCQKQLSENVFIDERRPVLLCDGKLCLRVLQDLFSLTIVEM GASACGROUPXVIII_14_PE61 ISOFORMIN KAP--GVYPAASEPPYVNVTCQKQLSENVFIDERRPVLLCDGKLCLRVLQDLFSLTIVEM GORGO2A_26_PE6 NOISO KSS--SVYPLSQDLPYVRIIYQKPYYLGPV-VEKRAVLLCDGKLRLSTVQQTFGLSLIEM HORSE15_74_PE14 NOISO KST--PVYPCSRDLPYVHITYQKFYYVGPV-VEKRAVLLCNGKLRLSTVQQTFGLSLIEM HS2_PE405 ENSG00000163026 KSS--SVYPLSQDLPYVHIIYQKPYYLGPV-VEKRAVLLCDGKLRLSTVQQTFGLSLIEM HS2_PE406 ISOFORMIN KSS--SVYPLSQDLPYVHIIYQIPTGFFSL-LTVRALSR--------------------- LAMPAGS_1066_1_PE3 NOISO KSS--PSYPLSPDLPYVHITCQKSCFVGPV-VGKRDILLCNGKLRLSTLQETFGLSLIEM LOXAF20_38_PE7 NOISO KPS--PGYPLSQDPPYVHIIYQKPYYAGPV-VERRAVLLCHGKLRLSTLQETFGLSLIEM MACEUSCAFFOLD41370_PE1 NOISO ---PPSAYPLSQDPSFLLITCQKPSPAGPM-VDKRAVLLCDGKVRLQMVQQAFGLSLVEM MACMU13_24_PE8 ISOFORMIN KSS--SVYPLSQDLPYVHIIYQIVTGFFSL-LIMRALSH--------------------- MACMU13_24_PE9 ENSMMUG00000012340 KSS--SVYPLSQDLPYVHIIYQKPYYLGPV-VEKRAVLLCDGKLRLSTVQQTFGLSLIEM MICMUGS_3671_1_PE4 NOISO KPS--SAYPLFQDPPYVHIVYQKLHYAGPV-VEKRAVLLCDDKLRLSTVQQTFGLSLIEM MONDO1_764_PE8 ENSMODG00000009400 QPLPLTRYPLSQDPSFLLITYQKPSSAGPV-LDKRAVLLCDGKVRLQQVQQVFGLSLVEM MONDO1_764_PE9 ISOFORMIN QPLPLTRYPLSQDPSFLLITYQVPSGSSSL-LTAKASSH--------------------- MONDOUN_31_PE18 NOISO QPLAPTRYPLSQDPSFLLITYQKPSSAGPV-LDKRAVLLCDGKVRLQQVQQVFGLSLVEM MONDOUN_32_PE1 ENSMODG00000002152 QPLAPTRYPLSQDPSFLLITYQKPSPAGPV-LDKRAVLLCDGKMRLQQVQQMFGLSLVEM MONDOUN_32_PE2 ISOFORMIN QPLAPTRYPLSQDPSFLLITYQVPSGSSSL-LTAKASSH--------------------- MOUSE12_PE46 ISOFORMIN RVA--PAYPPSQDAPYVHLIYQVQSFLRNF--HYTGSSGIQSVLP-ATLWGRWGGRESEA MOUSE12_PE47 ENSMUSG00000051721 RVA--PAYPPSQDAPYVHLIYQNPCSVGPT--ERRAVLLCDGKLRLSTVQQMFGLHLVEM MYOLUGS_4810_PE3 NOISO KSS--PVYPLSEDLPYVHISYQKRYSVESV-VEKRDVLLCHGKLRLSTVQQTFGLTLVEM ORNAN2_7_PE6 NOISO TSS--ALYPLSQEPSFVHVIYQEKPHVGGSVVERRTFLLCDGRLRLSVIQRTFGLSLVEM ORYLA24_3_PE7 NOISO LNK-------------------------------RSVLTVDTPPCCHSF--LIWCFIKEI OTOGA4515_PE3 NOISO KPS--SVYPPFQDPPYVHVIYQKPHYVGLI-TEKRAVLLCNGKLRLSTVQQTFGLSLIEM PANTR2A_26_PE5 ENSPTRG00000011707 KSS--SVYPLSQDLPYVHIIYQKPYYLDPV-VEKRAVLLCDGKLRLSTVQQTFGLSLIEM PANTR2A_26_PE6 ISOFORMIN KSS--SVYPLSQDLPYVHIIYQIPTGFFSL-LTVRALSR--------------------- PIG3_109_PE13 NOISO KSP--SVYPLSEDLPYVHITCQKPYFVGPV-VEKRAVLLCNGKLRLSTVQQTFGLSLIEM POEGU3_109_PE6 NOISO RNL--PVYPSCQEPSFINITCQKQLSK-SDADESRAVLLCGGKLRLNIIQQIFNLSLVEM POEGU3_110_PE1 NOISO RIS--LAYPCSQEPPVVHVTYQKSFSNGSITEETKDVLLCDGKIHLSLVQQLFDLPVIEM PONPY2A_91_PE8 NOISO KSS--SVYPLSEDLRYVHIIYQKPYYLAPV-VEKRAVLLCDGKLRLSTIQQTFGLSLIEM PTEVAGS_3150_PE3 NOISO KSS--PVYPLSQDLPYVHITYQKPYFVGSV-VEKRDVLLCNGKLRLDTVQQTFGLCLIEM RABIT2_177_PE8 NOISO KPS--AVYPRSQEPPYVHVLYQKPCSVDPV--EKRAVLLCDGKLRLSALQ-QFGLSLIEM SORARGS_7136_PE2 NOISO RPS--PVYPLSRDLPYVHITCQXXXXXXXX-XXXXXXXXXXXXXXX-XXXXXXXXXXXXX SPETRGS_4731_PE4 NOISO KSS--PVYPLSKDLPYVHIIYQKPCYVGPV--ERRAVLLCNGKLRLSAIQQMFGLSLVEM TARSY37049_PE1 NOISO KSS--SGYPLSQDPPYVHVIYQKPCYEGLV-IEKRAILLCDGKLRLSTVQQVFGISLIEM TETNG14_PE545 NOISO KAQ--AAYPSASEPPYINVTCQKQLSENVFIDERRPVLLCDGKLCLRVLQDLFNLTIVEM TUPGBGS_4558_PE2 NOISO KFS--PAYPLSQDLPYVHIIYQKPYYIGPV--DKRAVLLCDGKLRLSTVQQTFGLSLIEM TURTRGS_2798_PE3 NOISO KSS--PVYPLSQNVPYVHITCQKSYFLGPV-VEKRAVLLCNGKLRLSTVQQTFGLSLIEM XENTR180_2_PE1 NOISO RPL-SASYLPCRQAPYVTVVCQDAYHP-EGPAMKRSILLCDNKLRLGTIQELFGLSLIEM MATCH CONSENSUS ???????YP????????????Q????????????R??LLC?????L??????F?????EM

AILMEGL192369_1_4_PE9 NOISO L-HDSHWILLCADSEGF--IPLTFTATQEITIRDGS-A--NVF----MD----------- ANOCA3_9_PE3 NOISO QHGL-SWIVLTADQEDF--IPLTFDTQQEVVIRDASAG--SSNSSKTLDVVSSTGGYRKI ANOCA3_9_PE4 NOISO KYGS-SWIVLAADNEGF--IPLTFKAKQEIIIREGS------------------------ BOVIN11_80_PE9 NOISO L-HDSHWILLCADSEGF--VPLTFTATQEIIIRDGR-S--DDF----RNSAS-------- CALJA14_89_PE17 NOISO L-HDSHWILLSADSEGF--IPLTFTATQEIIIRDGSLSRSDVF----RDSFS-------- CANFA17_22_PE8 ENSCAFG00000003949 L-HDSHWILLCADSEGF--IPLTFTATQEITIRDGS-T--NVF----TDSV--------- CANFA17_22_PE9 ISOFORMIN ------------------------------------------------------------ CAVPO18_7_PE5 NOISO L-HDSHWILLSADREGF--IPLTFTATQELTVRDGHRPSSEGP----RGSLP-------- CHICK3_PE1462 NOISO QHGS-SWIVLTADSEGF--VPLTFTSMQEVVVRDASMKGYSARSSKTLDIISSTEGCRHS CHICK3_PE1463 ENSGALG00000016499 KHGS-SWIVLTADKDGF--VPLIFKARQDIIIR--------------------------- CHICK3_PE1464 ISOFORMIN ------------------------------------------------------------ DANRE20_47_PE11 NOISO MHGP-MWITLVADADGF--VPLTFKHKDELTIRSARRKSPARPPSGADDFPPESPKSPSM DASNOGS_5924_PE3 NOISO L-HDSLWILLSADSEGF--IPLTFTATQEITIRDGGRARPEGC----TDPLC-------- DIPOR7709_PE1 NOISO L-HDSHWIVLCADSEGF--IPLTFTATQTVVVRDGGLSRVGDS----RDSHS-------- ECHTE81750_PE1 NOISO HWRDSLWILLSADSEGF--IPLTFTATQEVTIRDGSLCRSGVF----KDSRS-------- FELCAGS_4949_PE2 NOISO L-HDSHWILLCADSEGF--IPLTFTATQEITIRDGS-S--NVF----RDSQ--------- FUGRU16_1_PE12 ENSTRUG00000004936 LYGP-LWIVLVADTDGF--VPLTFKPKEEFTVRNGKRKSPLRTPDTS---CPSSPTPSSN FUGRU16_1_PE13 ISOFORMIN LYGP-LWIVLVADTDGF--VPLTFKPKEEFTVRNGKRKSPLRTPDTS---CPSSPTPSSN FUGRU16_1_PE14 ISOFORMIN ------------------------------------------------------------ FUGRU16_1_PE15 ISOFORMIN LYEL-EVIKSLGSKHILMMMPYNLVPCGLYWWR--------------------------- GASACGROUPXVIII_14_PE60 ENSGACG00000012380 MYGP-LWVVLVADADGF--VPLTFKPKEELTVRNGKRKTNLRTPGSPENSVPWSPPDLDV GASACGROUPXVIII_14_PE61 ISOFORMIN MYGP-LWVVLVADADGF--VPLTFKPKEELTVRNGKRKTNLRTPGSPENSVPSSPAPGQG GORGO2A_26_PE6 NOISO L-HDSHWILLSADSEGF--IPLTFTATQEIIIRDGSLSRSDVF----RDSFS-------- HORSE15_74_PE14 NOISO L-HDSQWILLCADSEGF--IPLTFTATQEIIIRDGS-PRSNVF----RDSLS-------- HS2_PE405 ENSG00000163026 L-HDSHWILLSADSEGF--IPLTFTATQEIIIRDGSLSRSDVF----RDSFS-------- HS2_PE406 ISOFORMIN ------------------------------------------------------------ LAMPAGS_1066_1_PE3 NOISO L-HGSHWILLCADSEGF--IPLTFTATQEIIIRDGR-S--DVF----RDSVS-------- LOXAF20_38_PE7 NOISO L----------------------------------------------------------- MACEUSCAFFOLD41370_PE1 NOISO QHGS-LWILLSTDSEGF--IPLTFSDSQEITIRDGS------------------------ MACMU13_24_PE8 ISOFORMIN ------------------------------------------------------------ MACMU13_24_PE9 ENSMMUG00000012340 L-HDCHWILLTADNEGF--IPLTFTATQEIIIRDGSLSRSDVF----RDSFS-------- MICMUGS_3671_1_PE4 NOISO LHXXXXXXXXXXXXXXX--XXXXXXXX-XXXXXXXXXXXXXXX----XXXXX-------- MONDO1_764_PE8 ENSMODG00000009400 QYGS-LWILLSADGEGF--IPLTFSAAQEVTIRDG------------------------- MONDO1_764_PE9 ISOFORMIN ------------------------------------------------------------ MONDOUN_31_PE18 NOISO QYGS-LWILLSADSEGF--IPLTFSAAQEVTIRDGS------------------------ MONDOUN_32_PE1 ENSMODG00000002152 QYGS-LWILLSADSEGF--IPLMFSAAQEVTIRDGS------------------------ MONDOUN_32_PE2 ISOFORMIN ------------------------------------------------------------ MOUSE12_PE46 ISOFORMIN Q----------------------------------------------------------- MOUSE12_PE47 ENSMUSG00000051721 LHEVLS----S--------IPSNHMVTHNLHGP-GGLF---------WSV---------- MYOLUGS_4810_PE3 NOISO L-HDSRWILLSADSEGF--IPLTFTAKQEILVRDGG-SRSNIF----RDSLS-------- ORNAN2_7_PE6 NOISO QH---------------------------------------------------------- ORYLA24_3_PE7 NOISO MAGP-LWVVLVADADGF--VPLTFKPKDELTVRNGKRKAALRPPGSPENSCPSSPAPHQS OTOGA4515_PE3 NOISO LH---------------------------------------------------------- PANTR2A_26_PE5 ENSPTRG00000011707 L-HDSHWILLSADSEGF--IPLTFTATQEIIIRDGSLSRSDVF----RDSFS-------- PANTR2A_26_PE6 ISOFORMIN ------------------------------------------------------------ PIG3_109_PE13 NOISO L-HGSHWILLCDDSEGF--IPLTFTATQEITIRDGR-S--DVF----RDCVS-------- POEGU3_109_PE6 NOISO QHGS-SWIVLTADSEGF--IPLMFTPAQEILIRDATAKGYSARSSKTLDIISSTQGCRST POEGU3_110_PE1 NOISO KHGS-SWIVLTADKDGF--VPLIFKATQEIIIR--------------------------- PONPY2A_91_PE8 NOISO L-HDSHWILLSADSEGF--IPLTFTATQEIIIRDGSLSRSDVF----RDSFS-------- PTEVAGS_3150_PE3 NOISO L-HDSRWILLSADSEGF--IPLTFTATQEIIIRDGE-S--LSS----LDSV--------- RABIT2_177_PE8 NOISO L-HDSHWILLTADSEGF--IPLAFTATQEIIIRDGFLSRADAF----RDS---------- SORARGS_7136_PE2 NOISO XXXXSHWVLLSADTEGF--IPITFTATQEIVIRDGS-SGPGTL----RDTLS-------- SPETRGS_4731_PE4 NOISO L-H--------------------------------------------------------- TARSY37049_PE1 NOISO L-HESHWILLSADSEGF--IPLTFTATQEIRIRDGSLSRSLVF----RDSSS-------- TETNG14_PE545 NOISO LYGP-LWIVLVADADGF--VPLTFKPKEEFTVRNGKRKTPLRTPDTS---CPSSPTPSSN TUPGBGS_4558_PE2 NOISO L-H--------------------------------------------------------- TURTRGS_2798_PE3 NOISO L-HXXXXXXXXXXXXXX--XXXXXXXHTQEVIRDGR-S--NDF----RGPSL-------- XENTR180_2_PE1 NOISO QLGPSLWIILTGDSEGF--IPLTFLANQEITIRDARISTTHPPLS--MDRNNSLQPS--- MATCH CONSENSUS ????????????????????????????????????????????????????????????

AILMEGL192369_1_4_PE9 NOISO -------------------------------------- ANOCA3_9_PE3 NOISO SSQSLDIDTSSMEVLREGSSQSLVGSSSS--------- ANOCA3_9_PE4 NOISO -------------------------------------- BOVIN11_80_PE9 NOISO -------------------------------------- CALJA14_89_PE17 NOISO --YSLDS-ASSLKVFTGLTAPNLHISGCSNHVDGMA-- CANFA17_22_PE8 ENSCAFG00000003949 ---SES-------------------------------- CANFA17_22_PE9 ISOFORMIN -------------------------------------- CAVPO18_7_PE5 NOISO --RSQEP-VLSCDDSADLAARSQDTPGCPHCVDG---- CHICK3_PE1462 NOISO ASESLDIT-SSLEVLRDCSSKALDGSSPSEQPSSKM-- CHICK3_PE1463 ENSGALG00000016499 -------------------------------------- CHICK3_PE1464 ISOFORMIN -------------------------------------- DANRE20_47_PE11 NOISO --EK---------------------------------- DASNOGS_5924_PE3 NOISO --AQSLD-PGPLEVLRDP-APNVSPAHAVSAAR----- DIPOR7709_PE1 NOISO -----GD-PTSLQVFGDLTSPS-ASPGCSPHLDNVADT ECHTE81750_PE1 NOISO ----LDP-SPPLRTLRNSPAQ---SVGAPNHLGSTE-- FELCAGS_4949_PE2 NOISO ---SLNP-GPSLEVYRELSVQSVDATSCPTHLGSMAW- FUGRU16_1_PE12 ENSTRUG00000004936 --PNPTIEA----------------------------- FUGRU16_1_PE13 ISOFORMIN --PN---------------------------------- FUGRU16_1_PE14 ISOFORMIN -------------------------------------- FUGRU16_1_PE15 ISOFORMIN -------------------------------------- GASACGROUPXVIII_14_PE60 ENSGACG00000012380 -------------------------------------- GASACGROUPXVIII_14_PE61 ISOFORMIN --PPAATESS---------------------------- GORGO2A_26_PE6 NOISO --HSPGA-VSSLKVFTGLAAPSLDTTDCCNHVDGMA-- HORSE15_74_PE14 NOISO --QSLDP-SPSHEVFRDHTAQSVDATGCSNHLGRMA-- HS2_PE405 ENSG00000163026 --HSPGA-VSSLKVFTGLAAPSLDTTGCCNHVDGMA-- HS2_PE406 ISOFORMIN -------------------------------------- LAMPAGS_1066_1_PE3 NOISO --LDLGL-EVC-----RDLAHS-IHTSCPNHLGSVA-- LOXAF20_38_PE7 NOISO -------------------------------------- MACEUSCAFFOLD41370_PE1 NOISO -------------------------------------- MACMU13_24_PE8 ISOFORMIN -------------------------------------- MACMU13_24_PE9 ENSMMUG00000012340 --RSPDS-VSSLKVFTGLAAPSLDTTGCSNHVDGMA-- MICMUGS_3671_1_PE4 NOISO --XXXXX-XXXXXXXXXXTVQNLVITGCSNHLASMAW- MONDO1_764_PE8 ENSMODG00000009400 -------------------------------------- MONDO1_764_PE9 ISOFORMIN -------------------------------------- MONDOUN_31_PE18 NOISO -------------------------------------- MONDOUN_32_PE1 ENSMODG00000002152 -------------------------------------- MONDOUN_32_PE2 ISOFORMIN -------------------------------------- MOUSE12_PE46 ISOFORMIN -------------------------------------- MOUSE12_PE47 ENSMUSG00000051721 -------------------------------------- MYOLUGS_4810_PE3 NOISO --QSLDS-GPCLEVFGEHTAQRLDATSYSNHLG----- ORNAN2_7_PE6 NOISO -------------------------------------- ORYLA24_3_PE7 NOISO --PAAAS------------------------------- OTOGA4515_PE3 NOISO -------------------------------------- PANTR2A_26_PE5 ENSPTRG00000011707 --HSPGA-VSSLKVFTGLAAPSLDTTGCCNHVDGMA-- PANTR2A_26_PE6 ISOFORMIN -------------------------------------- PIG3_109_PE13 NOISO --ES------------PYTAQSVDTTGCSNHFGCMA-- POEGU3_109_PE6 NOISO SSESLDIT-SSLEVLRDCSSKTLDTISPSEQPSNKM-- POEGU3_110_PE1 NOISO -------------------------------------- PONPY2A_91_PE8 NOISO --HSPGS-VSSLKVFTGLAAPSLDTTGCCNHVDGMA-- PTEVAGS_3150_PE3 NOISO ----------------PCLVFKLDTAFCSNDLRSMA-- RABIT2_177_PE8 NOISO -------------------------------------- SORARGS_7136_PE2 NOISO --PSHDP-GHSLDMLGDCAQR-LDI------------- SPETRGS_4731_PE4 NOISO -------------------------------------- TARSY37049_PE1 NOISO ----LDP-VPPLKFFAGLTAPNSDTTGCCNRFNSSAW- TETNG14_PE545 NOISO --P----------------------------------- TUPGBGS_4558_PE2 NOISO -------------------------------------- TURTRGS_2798_PE3 NOISO --E------VF-----RHAAQSVDATGCSNHFGSIV-- XENTR180_2_PE1 NOISO --SSVT-------------------------------- MATCH CONSENSUS ??????????????????????????????????????


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