Alignment of the gene Family HOG000111403 of HOGENOM

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Threshold: 50% 80% 100%
Size: Bigger Smaller Normal
Isoforms are ON
AILMEGL193090_1_PE15 NOISO ------------MPGSMAPLKKPRNTTRVPLALNPLKSKDVLAVLAERNQAIMPVGAWVE BOVIN29_31_PE24 NOISO ------------MPRSMAPLKKPRNTSKLPLALNPLKSKNVLAVLAERNQAIVPVGAWVE CALJA11_24_PE22 ENSCJAG00000008183 ------------MLGSMA-RKKPRNNTRLPLALNPLKSKDVLAVLAERNQAIVPVGAWVE CALJA11_24_PE23 ISOFORMIN ------------------------------------------------------------ CANFA5_13_PE8 ENSCAFG00000010996 ------------------------------------------------------------ CAVPO19_22_PE3 NOISO ------------MPGRMCPLKKHRNVADLPLALNPMKSKDVLAVLAERNQAVVPVGAWVE CHOHOGS_4625_PE1 NOISO ------------MPGRMAPHKKSRNSPSLPLALNPLKSKEVLAVLAERNQTIVPVGAWVE DANRE5_61_PE20 NOISO ------------------------------------RQVRDVKVLAERNPAVAPVGVWVE DASNOGS_4202_PE1 NOISO ------------MPGKMAPLKKSRNPPSLPLALNPLKSKEVLAVLAERNQSIVPVGAWVE DIPORGS_3897_PE1 NOISO ------------MPGRVAPLKKPRSATALPLALNPRKSHDVLAVLAERSEVVAPVGAWVE ERIEUGS_5103_PE1 NOISO ------------MPGCMAPLQKPGNGRRAPLALNPQKSKDVLAVLAERNQAVVAVGAWVE GORGO11_127_PE16 NOISO ------------MLGSMA-RKKPRNTSRLPLALNPLKSKDVLAVLAERNEAIVPVGAWVE HORSE7_34_PE29 NOISO ------------MPGSMAPLKKTGNTTRLPLALNPLKSKDVLAVLAERNQAIVPVGAWVE HS11_PE3255 NOISO ------------MLGSMA-RKKPRNTSRLPLALNPLKSKDVLAVLAERNEAIVPVGAWVE LAMPA4421_PE1 NOISO ------------------------------------------------------------ LOXAF50_17_PE7 NOISO ------------MPGRMAPLKKPRNTPRLPLALNPLKSKDVLAVLAERNQAVVPIGAWVE MACMU14_126_PE13 NOISO ------------MLGSMA-PKKPRNTTRLPLALNPLKSKDVLAVLAERNQAIVPVGAWVE MICMUGS_2724_PE11 NOISO ------------------------------------------------------------ MOUSE9_PE524 NOISO LTSGQAFISQKSMPGGMAPLKKPRNPTKLPLALNPTKSKDVLAVLAERNQAIIPVGAWVE MYOLUGS_3577_PE2 NOISO ------------------------------------------------------------ OCHPRGS_3104_PE4 NOISO ------------MPANMAPLKKPPDATRLPLALNPRRSKAILAVLAERNQAVVPVGAWVE PANTR11_128_PE1 NOISO ------------MLGSMA-RKKPRNTSRLPLALNPLKSKDVLAVLAERNEAIVPVGAWVE PIG9_52_PE4 NOISO ------------VPGSMAPLKKPRNSTKLPLALNPLKSKDVLTVLAERNQAVVPVGAWVE PONPY11_125_PE13 NOISO ------------MLGSMA-RKKPRNTSRLPLALNPVKSKDVLAVLAERNQAIVPVGAWVE PROCAGS_5410_PE2 NOISO ------------MPGRMARLKKSRNTTRQHLALNPLKSKDVLAVLAERNQAVVPVGAWVE PTEVAGS_2173_PE1 NOISO --------------GSMAPHKTSRNTSKLPLALNPLKSKDVLAVLAERNQAIVPVGAWVE RABIT1_94_PE15 NOISO ------------MPGGMAPLKKPPNSTRLPLALNPQKSKDVLAVLAERNQTIVPVGAWVE RAT8_PE404 NOISO ------------MPGGMTPLKKPRNPTKLPLTLNPTKSKDVLAVLAERNQAIVPVGAWVE SORARGS_4153_PE1 NOISO ------------MPRNMGPHKQPRGSASPPLAL---KSQKVLAVLAERNQTVMPVGAWVE SPETRGS_3506_PE8 NOISO ------------MQGRMAPLKKSQNSTKLPLALNPTKSKDVLAVLAERNQAVIPVGVWVE TARSYGS_4834_PE1 NOISO ------------MPGSMAPLKKPRNTTKSPLALNPLKSKDVLAVLAERNPAIVPVGAWVE TURTRGS_2035_PE12 NOISO ------------MPGSMAPIKKLRNTTKLPLALNPLKSKDVLAVLAERNQAIVPVGAWVE MATCH CONSENSUS ????????????MPG?MAPLKKPRN???LPLALNPLKSKDVLAVLAERNQAIVPVGAWVE

AILMEGL193090_1_PE15 NOISO PALPDSSEVPAYTSAYMIEEELKEQLRKKQEALKHFQRQVKHRVNQQIRLRKKQQFQRSY BOVIN29_31_PE24 NOISO PAPPDSSEVPAATSAYIIEEELKEQLRKKQEALKHFQRQVKSRVNQQIRLRKKQQLQRSY CALJA11_24_PE22 ENSCJAG00000008183 PASPDSSEIPAYTSAYLIEEELKEQLRKKQEALKHFQKQVKYRVNQQIRLRKKQELQKSY CALJA11_24_PE23 ISOFORMIN ------------------------------------------------------------ CANFA5_13_PE8 ENSCAFG00000010996 ------------------------------------------------------------ CAVPO19_22_PE3 NOISO PASPNSYEIPAYTSACIIEEELKEQLRRKEEALKHFQRQVKHRVNQQIRLRKKQQLQKSY CHOHOGS_4625_PE1 NOISO PASPDISEIPAHTSAYMIEEELKEQLRKKEAALKRFQRQVKYRVNQQIRLRKKQQFQKSY DANRE5_61_PE20 NOISO SGE-ECQEHPAVS-LNLSLEQISETRREKEESLRRFQDAVRERVSQQAQLRKQQQLIRSY DASNOGS_4202_PE1 NOISO PALPDSSEIPAHXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX DIPORGS_3897_PE1 NOISO PASPQCREIPAHXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX ERIEUGS_5103_PE1 NOISO PASPASWEVSAHXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQLQKSY GORGO11_127_PE16 NOISO PASPGSSEIPAYTSAYLIEEELKEQLRKKQEALKHFQKQVKYRVNQQIRLRKKQQLQKSY HORSE7_34_PE29 NOISO PASPHSSEIPASTSAYMIEEELKEELRKKQEALRRFQRQVKHRVNQQIRLRKKQQLQKSY HS11_PE3255 NOISO PASPGSSEIPAYTSAYLIEEELKEQLRKKQEALKHFQKQVKYRVNQQIRLRKKQQLQKSY LAMPA4421_PE1 NOISO ------------TSAYIIEEELKEQLRKKQEALKHFQRQVKRRVNQQIRLRKKQELQKSY LOXAF50_17_PE7 NOISO PASPDSSEIPAYTSACVIEEELKEQLRKKQEALKHFQNQVKRRVNQHVRLKKKQQLQRSF MACMU14_126_PE13 NOISO PASPGSSEIPAYTSAYLIEKELKEQLRRKQEALKHFQKQVKYRVNQQIRLRKKQQLQKSH MICMUGS_2724_PE11 NOISO ------------TSAYIIEEELKEQLRKKQEALKCFQRQVKRRVNQQIRLRKKQQLQKFY MOUSE9_PE524 NOISO PASPNWSGIPAHTSAYVVEEEIKEQQRRKQESLRHFQRQVRHRVNQRVKLRKKQQLHKSY MYOLUGS_3577_PE2 NOISO ------------TAAYVIEKEIKEQFRR-QEALKRFQRQAKHRVNQRVRLRKKQQLQKFY OCHPRGS_3104_PE4 NOISO PAVPDSSDIPAYTSACLVEEELKEKLRKKQEALKRFQRQVKHRVNQQIRLRKKQQLLKLR PANTR11_128_PE1 NOISO PASPGSSEIPAYTSAYLIEEELKEQLRKKQEALKHFQKQVKYRVNQQIRLRKKQQLQKSY PIG9_52_PE4 NOISO PAPPGSTEVPAHTSAYMIEEELKEQLRKKQEALKHFQRQVKRRVNQQIRLRKKQQLQRSY PONPY11_125_PE13 NOISO PASPGSSEIPAYTSAYLIEEELKEQLRKKQEALKHFQKQVKYRVNQQIRLRKKQQLQKSY PROCAGS_5410_PE2 NOISO PASPDSSEFPAYTSACVIEEELKEQLRKKQEALKDFQSQVKHRVNQHVRLRKKQQLQRSY PTEVAGS_2173_PE1 NOISO PASPHSSEIPAYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX RABIT1_94_PE15 NOISO PASPDSSEIPAYTSACMIEEELKEQQRKKQEALKRFQRQVKCRVNQQIRLRKKQQLQKSY RAT8_PE404 NOISO PASPNWSGIPAHTSAYILEEEIKEQQRRKQESLRHFQRQVKHRVNQQAKLRKKQQLDKSY SORARGS_4153_PE1 NOISO PALPDRSEVPAHXXXXXXEQQLKEQLRRKQEALKHFQRQVKHRVNEQIRLRKKQQLQKFY SPETRGS_3506_PE8 NOISO PASPNSLEIPASN----------------------------------------------- TARSYGS_4834_PE1 NOISO PASPDSSEIPAYTSAYMIEEELKEQLRKKQEALKHFQKQVKHRVNQQIRLRKKQQLQKSY TURTRGS_2035_PE12 NOISO PAPPDSSAVPASTSAYMIEKELREQLRKKQEALKHFQRQVKRRVNQQIRLRKKQQLQRSY MATCH CONSENSUS PASP?SSEIPA?TSAY?IEEELKEQLRKKQEALKHFQ?QVK?RVNQQIRLRKKQQLQKSY

AILMEGL193090_1_PE15 NOISO EAAEKEGAIAMQSSDPAHLTPK-RTSVFPNNLDAAIGSARLPPSQMLGDGMDDRENQNEL BOVIN29_31_PE24 NOISO EAAEKEGSIAMYSSDPAHLTPK-RTSVFPSNLNAAIGRARLPPPQMLEGGIEDRENQSEL CALJA11_24_PE22 ENSCJAG00000008183 ERAEKEGSIAMQSS-PAYLTFK-RTGVFPKNLNAVIGSSRLSPSLMLGEGTDDEENQNEL CALJA11_24_PE23 ISOFORMIN ----------MQSS-PAYLTFK-RTGVFPKNLNAVIGSSRLSPSLMLGEGTDDEENQNEL CANFA5_13_PE8 ENSCAFG00000010996 -----------QSSDPAHLTPK-KTSVFSNNLNAAIGSARLPPSQMLGDGIDDRENQNEL CAVPO19_22_PE3 NOISO EAAEKGGSITTRSFDPGHLTLK-RTSVFPSNSNAAFGSFSLPTSQKLGDAIE---NQSEL CHOHOGS_4625_PE1 NOISO EAAEKEGIIAMQSSDPAHLTPKRRTSVFPNNLNAAIVSSRLSPSQMLGDGIEDGENQNEL DANRE5_61_PE20 NOISO QTVEWEGKILQLTTKAVHRP-LPQTNVFPSWTYAEQVICSPSSHSASVDGTESSS----- DASNOGS_4202_PE1 NOISO XXAEKEGIIAMHSSDPAHLTPKRRTSVFPNSLNAAIVSSRLPPSQMLGDGVEDGENQNEL DIPORGS_3897_PE1 NOISO XXVEKEGSIAMQSSDRTL----KRTSVFPSTLNAAIGSSVLPPSQMLGDTVDNGENHSEL ERIEUGS_5103_PE1 NOISO EA-EKEGCIVMHSSDPAHLTPK-QTSVFPNTLNVAIGTARLPLSQMCSNETEDRENQDES GORGO11_127_PE16 NOISO ERAQKEGSIAMQSS-AAHLTSK-RTSVFPNNLNVAIGSSRLPPSLMPGDGIEDEENQNEL HORSE7_34_PE29 NOISO EAAEKESSIAMQSSDPAHLTPK-RTSVFPNNLNAAIGSARSLLSEMLGDGIEDRENQNEL HS11_PE3255 NOISO ERAQKEGSIAMQSS-ATHLTSK-RTSVFPNNLNVAIGSSRLPPSLMPGDGIEDEENQNEL LAMPA4421_PE1 NOISO EAAEKEGSIAMHSSDPFHLTPK-RTSVFSNTLNAAVGSAGLPPSQMLEDGIEDRENQNEL LOXAF50_17_PE7 NOISO EAAEKEGSIAMQSSDPAHLTRKRRTSVFPNNLNAAIGSSWLPPS------PEDEENQNEL MACMU14_126_PE13 NOISO ERAEKEGSVAMQSS-AARLTSK-RTSVFPNNLNAAIGSSRLPPSLMPGDGIEDEENQNEL MICMUGS_2724_PE11 NOISO EAAEKEGSIAMQSSDPAYLTPK-RTSVYPHNLNAAIGSSRLPASQMLEDKIENGENQNEL MOUSE9_PE524 NOISO KAAEKEGSIAMQYSDLAHLSSK-RTSVFPSNLNAAVGRFRLPTSQVLGDAIEDGE--NQL MYOLUGS_3577_PE2 NOISO EEAEKEDTVGMLPSDLEHLTSK-RTRVFPKTLNAAIGSAWSPSSQKL-DGIQDRENENQL OCHPRGS_3104_PE4 NOISO EAAEKEGSVVMQSSHPAHFAPE-TTRVFPKRLNAVVGSPGLGPSQVLGEELEDAENGNEL PANTR11_128_PE1 NOISO ERAQKEGSIAMQSS-ATHLTSK-RTSVFPNNLNVAIGSSRLPPSLMPGDGIEDEENQNEL PIG9_52_PE4 NOISO EAAEKEGSIAMHSSAPAQLTPK-RTSIFLNTLNAAIGSARLPPSQMLEDGIEDRENQNEL PONPY11_125_PE13 NOISO ERAQKEGSIAMQSS-AAHLTSK-RTSVFPNNLNVAIGSSRLPPSLMPGDGIEDEENQNEL PROCAGS_5410_PE2 NOISO EAINEN-PIAIES---------------------------------------------IE PTEVAGS_2173_PE1 NOISO XXAEKEGSIAMYSSDPACLTPR-RTSVFPNNLNAAIESARLPPSRMLGGGIEDRENQNRL RABIT1_94_PE15 NOISO EAAEKEGCIAMQSSNTAHFTSK-RTSVFPKKLNAAVGSPRLPRSQMLGDGIEDGENENEL RAT8_PE404 NOISO KAAEKEGSIAIRYSDSAHLTSK-RTSVFPRNLNAAVGSFRLPTSLVLGNATDDAENQNQL SORARGS_4153_PE1 NOISO EAAEKEGSVAMQSSELVLLTPR-SSSIFQSNLNAAMESE---------NRLEDKETQNGL SPETRGS_3506_PE8 NOISO -KAEKEGSIAMQSSDPAHFTPK-GTSIFPSNLNSAIGSSGLPASQMFGSAIKDGENQNEL TARSYGS_4834_PE1 NOISO EVAEKEDFRVMQSL-PAHLTSK-RTNIFSNNSNAAIGSSRLPPSQILGDGREDEENQNEL TURTRGS_2035_PE12 NOISO EAAEKEGSIAMHSSDPANLTLK-RTSVFPNHLNAAIGSARLPPSRKLEDGIEDRENQNEL MATCH CONSENSUS EAAEKEGSIAMQSSDPAHLT?K?RTSVFPNNLNAAIGS?RLPPSQMLGDGIED?ENQNEL

AILMEGL193090_1_PE15 NOISO FQQQAQALSQTMKQARHRLASFKTVNKK-NVSVFPDGRRKIFPPQEKA-LCRKPSSLKIN BOVIN29_31_PE24 NOISO FQQQAQALSQSMKQARHRLASFKTVNQK-DAPEFPDDRKKSFPTQEKA-LCRKPSFTRIN CALJA11_24_PE22 ENSCJAG00000008183 FQQQAQALSQTMKQARHQLASFKTVSKK-KGSVFPDDGRKSFPTQETV-LSKKPASPGIN CALJA11_24_PE23 ISOFORMIN FQQQAQALSQTMKQARHQLASFKTVSKK-KGSVFPDDGRKSFPTQETV-LSKKPASPGIN CANFA5_13_PE8 ENSCAFG00000010996 FQQQAQALSQTMKQARHRLASFKTVNKK-NASMFPDGRRKTFPPQEEKVLITSINHHPSN CAVPO19_22_PE3 NOISO FQQQAQAVIYIVYEIELRGTTFNFIAMV-NGSIVIDQPRDSERNREKY-VCKKEQKMRLN CHOHOGS_4625_PE1 NOISO FQRQAQALSKTMKRARHQLASFKTVS-K-TASVFLDDRRKF-TTKKN-SLCRKPASIKIN DANRE5_61_PE20 NOISO SRHLTHNVSKVRKHVRHRLAARQTVQDGEDLSQLPGGRWKISPARNKP------------ DASNOGS_4202_PE1 NOISO FQQQAQALSQTMKQARHQLASFKTVSRK-RASVILSGRRS-FATEEXXXXXXXXXXXXXX DIPORGS_3897_PE1 NOISO FQQ-AQALSQTMKQARHQLASFKTVSEK-KMLXXXXXXXXXX-XXXXTTPSKKPENIKIN ERIEUGS_5103_PE1 NOISO FQQQAQAXXXXXXXXXXXXXXXXXXX----------------X-XXXX--------XX-- GORGO11_127_PE16 NOISO FQQQAQALSETMKQARHRLASFKTVVKK-KGSVFPDDGRKSFLTREEV-LSRKPASTGIN HORSE7_34_PE29 NOISO FLQQAQALSQTMKQARHQLASFKTVS-K-NASVFPDGRRKSSPTQENL-LCGKPAFFRIN HS11_PE3255 NOISO FQQQAQALSETMKQARHRLASFKTVIKK-KGSVFPDDGRKSFLTREEV-LSRKPASTGIN LAMPA4421_PE1 NOISO FQQQAQALSQTMKQARHQLASFKTVNKK-NAPVFPDDRKKSFPTQEEV-PCKKPAFIKIN LOXAF50_17_PE7 NOISO FQQQAQALSQTMKQVCHRLASLKTMGKK-KASVFPDDERKSVPTQEFL-LLGKFAFSALS MACMU14_126_PE13 NOISO FQQ-AQALSQTMKQARHRLASFKTVGEK-KGSVFPDDGRKSFPTREKV-LSRKPASTGIN MICMUGS_2724_PE11 NOISO FQQQAQALSQTMKQARHRLASFKTVTKE-KASVFPDDGRKSVPTQEVN-FRMHCLIXXXX MOUSE9_PE524 NOISO FQQQAQALSQTMKQARHQLASFKTVSEK-KTPVLPNGGRKGCPTQEGL-GCGKISFVAVS MYOLUGS_3577_PE2 NOISO IQQALAXX-XXXXXXXXXXXXXXXXXXK-YAAVFPEDTRKSCPTQQVNFL---------- OCHPRGS_3104_PE4 NOISO FQQQAQAXXXXXXXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXRA-VSRKPGFIRIK PANTR11_128_PE1 NOISO FQQQAQALSETMKQARHRLASFKTVIKK-KGSVFPDDGRKSFLTREEV-LSRKPASTGIN PIG9_52_PE4 NOISO FQQ-AQALSQTMKQARHRLASFKTVNEK-NAPVFPDDRKKSLANQEKA-ICRKPAFAKIN PONPY11_125_PE13 NOISO FQQQARALSETMKQARHRLASFKTVIKE-KGSVFPDDGRESFLTPEEV-LSRKPASAGTN PROCAGS_5410_PE2 NOISO FQHVKQPLSQTMKEVRHRLASVKTVGEK-NASVFPDDRK-SVPTQEXX-XXXKPAAIRIN PTEVAGS_2173_PE1 NOISO FHQQAQALSQTMKQARHRLASFKTVSKN-NTSVFPDGTRKSFPTQEQA-LCRKLSSIRIN RABIT1_94_PE15 NOISO FQQQAQALSQTMKLARQRLASFKTVTKE-KASVFTDDKRKSILTQERA-LSRKPAFIRIN RAT8_PE404 NOISO FEQQAQALSQTMKQARHQLASFKTVSEK-KTSVFLNGGKKSSPTQEDL-GCGKISSVVVS SORARGS_4153_PE1 NOISO FQQQAQALCQTMKQARHQLASLKTVSHK-DTPLHPRGPRRSYPTREVKK----------- SPETRGS_3506_PE8 NOISO FQQQAQALSQTMKQVRHRLASHKTVSKK-KSSVFPDGMRKSFSIQQVN-FPLC------- TARSYGS_4834_PE1 NOISO FQQQTQALSQTVKQACHQLASFKIARKK-KGSEFPDDGRKSFSTQEKA-LSRKPASTGIN TURTRGS_2035_PE12 NOISO FQQQAQALSQTMKEARQRLASFKTVNKK-NASVFPDDRKKNFPTQEKA-LCTKPSFTRIN MATCH : CONSENSUS FQQQAQALSQTMKQARHRLASFKTV?KK???SVFPDD?RKSFPTQE???L??KP????IN

AILMEGL193090_1_PE15 NOISO TRSRGQLTFK----FGLLTTLHYQTFIENQYCFFLEPDSEESSSIMIDKKGRENLIWG-- BOVIN29_31_PE24 NOISO IGVRGDLPLEV--HQGLLTPADYQKFMDDQSLSHVE--PEESSSVMIDKKGKKHLSWG-- CALJA11_24_PE22 ENSCJAG00000008183 IGIRGELPIKV--HRGLLAAVPYQNYMENQELDCEEPDYVEASSIITDEKGKENLFGRDH CALJA11_24_PE23 ISOFORMIN IGIRGELPIKV--HRGLLAAVPYQNYMENQELDCEEPDYVEASSIITDEKGKENLFGRDH CANFA5_13_PE8 ENSCAFG00000010996 IGTRGQLTFRSIKIFGLFTTLYYQKFVENQERFFDEPDSEESSSTTVDKREKENLFWG-- CAVPO19_22_PE3 NOISO KICQGEMICKA--NHGIYEFITHQSGMNQSGLEIAQTIYSA--SMPCTDLGKLRVFRG-E CHOHOGS_4625_PE1 NOISO IGVRGEFPLKV--HQDHITAIHYQNLMENQ-----EIDFEESVPIMIDEEGRDDL-FG-- DANRE5_61_PE20 NOISO ----------------------------------------------------ESHTWK-- DASNOGS_4202_PE1 NOISO XXXXXX--------XXXXXXXXXXXXXXXXXXXXXELDFGESLFIMTDDEGRDNL-FG-- DIPORGS_3897_PE1 NOISO TETRREFPLNN--HQDLLTTVHYQNFMDNQ-----ESDHEDISSVMTDEKQR-ALICG-- ERIEUGS_5103_PE1 NOISO -----------------XX--------------XXXXXXXXXEVFLTYIKKKENLFWR-- GORGO11_127_PE16 NOISO TGIRGELPIKV--HQGLLAAVPYQNYMANQEFDHEEPDYEESSSLVTDEKGKEDLFGRGQ HORSE7_34_PE29 NOISO IGTRGELPFL-------LNTVHYQKCIENQLMDIWEPESEESSSITVDKKGRENLFWE-- HS11_PE3255 NOISO TGIRGELPIKV--HQGLLAAVPYQNYMENQELDYEEPDYEESSSLVTDEKGKEDLFGRGQ LAMPA4421_PE1 NOISO IGTSGKSPFEV--QQDLLTPVHDQKFMEDQ-----ESDSEESPSIMIDKKGKENLSWG-- LOXAF50_17_PE7 NOISO ENLQINLF----------------------------------------------IFEK-- MACMU14_126_PE13 NOISO TGIRGELPIKV--HQGLLAAVPYQNYMENQELDYEEPDYEKSSSLVTDEKAKEDLFGRDQ MICMUGS_2724_PE11 NOISO XXXXXXXXXXX--XX-----------------------------------X---XXXX-- MOUSE9_PE524 NOISO E-------------------------------------------------ERDALFVS-- MYOLUGS_3577_PE2 NOISO -----------------------------------------------ISFLKEKLFWK-- OCHPRGS_3104_PE4 NOISO ---RGEFPFKR--L---LATVHE-SFREN----QFELDHEEVSSVKTNEEKREDLFQG-- PANTR11_128_PE1 NOISO TGIRGELPIKV--HQGLLAAVPYQNYMENQELDYEEPDYEESSSLVTDEKGKEDLFGRGQ PIG9_52_PE4 NOISO IGVRRELPFEV--QQGLSTPVPYQKFMEDQVGKYKEPDSEEFSSILIDKKGKENLSWG-- PONPY11_125_PE13 NOISO TGIRTELPIKV--HQGLLAAVPYQNYMENQELDYEEPDYEESSSLVTDEKGKEDFFGRGQ PROCAGS_5410_PE2 NOISO TKTREVLLKG---RQSLLAVAHYQNFMQSEPVL--KYDTGESSSVITDEKGRESLLRE-- PTEVAGS_2173_PE1 NOISO IETRGDLPFKV--HQGLLNTVCYQNVMENQ-----EHDSEKSSSIMIDKKERESLFSW-- RABIT1_94_PE15 NOISO IG-RGEFSFKG--HQDLLTTVHYENYMEDQPLCFLELDYEEISSVVTNEEGGD-LFQG-- RAT8_PE404 NOISO E-------------------------------------------------ERDNLFES-- SORARGS_4153_PE1 NOISO --------------KT----------------------------LLVSLKIKENL-IG-- SPETRGS_3506_PE8 NOISO ------------------------------------------------GFKRDDLFWG-- TARSYGS_4834_PE1 NOISO IGTRGKLPFKV--HQGLLTTVHYQNFMENQ-----EPDYEEFSSIMTSEKEREDLFGGD- TURTRGS_2035_PE12 NOISO IGIXXXXXXKP--HQGLLTLVDYQKFMEDQ-----EPDTEESSSIMIDKKGKKNLSWG-- MATCH CONSENSUS ?G?RG?LP????????LL??V?YQ??ME?Q?????E?D?EE?SS???D?KGKE?LF????

AILMEGL193090_1_PE15 NOISO -DQQDLLSEDRDKPFSKVQKVQFKNPLFAVMKEEEEL--DLQGLQNILPEAQNYLPEAQG BOVIN29_31_PE24 NOISO -DQEALFPEDKDIPFSRVQKVQFKTPLFDVIEEEEVK--QL--HQDVLPEAQDYLPEAQG CALJA11_24_PE22 ENSCJAG00000008183 QDQQDILSEDKNKPF-RVQKVKFKTPLFVVMEEGEQKQLHFEGLQDILPEAQDDFPEAED CALJA11_24_PE23 ISOFORMIN QDQQDILSEDKNKPF-RVQKVKFKTPLFVVMEEGEQKQLHFEGLQDILPEAQDDFPEAED CANFA5_13_PE8 ENSCAFG00000010996 -QQQDLLSEDREKPFSRVQKVQFKNPLFAVMKEEEQKQLDLQDLQDILPEAQDYLAEAQG CAVPO19_22_PE3 NOISO KTQSSLHYQVTERPFSKFRKVKFKNPLFEVMEEKEQNQLGCQSVQSIPP----------- CHOHOGS_4625_PE1 NOISO -DQQDFLSEVKHKHFGRVQLP---K----------------------------------- DANRE5_61_PE20 NOISO -DQKDYTERGEE------------------------------------------------ DASNOGS_4202_PE1 NOISO -RQENLLSEVNDKHFSRVQKVKFKNPLFAIMEEGELKRKVLQSSQNTLLEAQNYLPEVQG DIPORGS_3897_PE1 NOISO -NQQDLLSEDKEKSFSRAQKVKFKNPLFALMEEQK--QLYFQGLQDILTEAQDCLPEAQG ERIEUGS_5103_PE1 NOISO -DQQDFPSGDKNIPFSGVQKVQFKNPLFAVMGEEHVKHTH---LQNILPRAQDCFPEACG GORGO11_127_PE16 NOISO QDQQAIHSEDKNKPFSRVQKVKFKNPLFVLMEEEEQKQLHFEGLQDILPEAQDYFPEAQG HORSE7_34_PE29 NOISO -GWQDLLCEDKDKPFSRVQKVHFKNPLFAVMEEKELERLALQGLQDILPETHDYLPEAQG HS11_PE3255 NOISO QDQQAIHSEDKNKPFSRVQKVKFKNPLFVLMEEEEQKQLHFEGLQDILPEAQDYFLEAQG LAMPA4421_PE1 NOISO -YQQDLLSEDKDITFNRVQKVQFKNPLSAMTEEKEVE--QL--HQDILPKAQDYLPEAQG LOXAF50_17_PE7 NOISO -WRGNHLSEIKDKPFNRVQKVQFKNPLFDVAEEEELNELH---LQDILPEAQDYLPEAQS MACMU14_126_PE13 NOISO QDQQDILSEDKNEPFSRVQKVKFKNPLFVLMEEEQQKQIHFEGLQDILPEAQDYLPEAQG MICMUGS_2724_PE11 NOISO --XXX-----------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXILPEAQDYFTETQG MOUSE9_PE524 NOISO -CQQDFLSEDKEKAFSKVQKVKFKNPLSVVIKEDERKQLHPHSLQAVLPEAQDYFVEVQS MYOLUGS_3577_PE2 NOISO -NQQGFFSEEKNKTFSRVQKIQLKTPLYAVIQEEQL-----NDLQDILPETQDYLSETQG OCHPRGS_3104_PE4 NOISO -DQEEFLSEDKDASCCRIQKVKFKNPLFV-MEQEEQIQLHPQSFHHIPQ-DQ-DHQETKG PANTR11_128_PE1 NOISO QDQQAIHSEDKNKPFSRVQKVKFKNPLFVLMEEEEQKQLHFEGLQGILPEAQDYFPEAQG PIG9_52_PE4 NOISO -DQQDLLSEDKDIPFSRVQKVHFKNPLFSVMEEEEVK--QL--RQGVLPQARDYFPEAQG PONPY11_125_PE13 NOISO QDQQAILSEDKNKPFSRVQKVKFKNPLFVLMEEEEQKQLHFEGLQDILPEAQDYFPEAQG PROCAGS_5410_PE2 NOISO -DPQDLLSEIKDKPFNRVQKVQFKNPLFDVIEGEELKKLR---LQDVLPKAQDYLPEVHS PTEVAGS_2173_PE1 NOISO -DQQDLLSEDKDKPFSRERKVQFKNPLFAVMEEEELKKLHLHGLQDILPETQDYLSKARG RABIT1_94_PE15 NOISO -DQQDLLSEDNDVCFSKVQKVKFKNPLFVVMEGEEQTPSYLQGFQHILPEAQDHLPEAQG RAT8_PE404 NOISO -CQQDLLSEDKEKALSKVQKVKFKNPLSVVIKEDEGKQLYPHSLQPVLPEAQGYFVEVKS SORARGS_4153_PE1 NOISO -VDQGLLSEEGNIPVVRVQEVQLRNSVFDVMDQEKIEQFRLLGLQNIQ-----------G SPETRGS_3506_PE8 NOISO -DKQSLFSEDNDKPFSRVQKVKFKNPLFVVIEEKEQKQSHFQGLE-----AQDYPL---- TARSYGS_4834_PE1 NOISO --QQDIFSEDEDKPVSKVQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX TURTRGS_2035_PE12 NOISO -DQQDLLFEGKDIPFSTVQKVQFKNPLFAVMEEEEVR--QL--HQDVLPEAQDYLPEAPG MATCH CONSENSUS ?DQQDLLSEDK?KPFSRVQKV?FKNPLF?VMEEEE?K?L????LQDILPEAQDY?PEAQG

AILMEGL193090_1_PE15 NOISO DLIEVQSVELEAESVEPEAESVEPR-----LNTLAIELESQAVEPEAQATEPKAQ----- BOVIN29_31_PE24 NOISO D-------LTSVLDVEWEAQRCEPR-----LSTQHIDLEGHTVEPKAQ------------ CALJA11_24_PE22 ENSCJAG00000008183 DLLETQGDLKGIQ-------SIEPDTQAVELNVQVTEPEGQAVEPEGQPV---------- CALJA11_24_PE23 ISOFORMIN DLLETQGDLKGIQ-------SIEPDTQAVELNVQVTEPEGQAVEPEGQPV---------- CANFA5_13_PE8 ENSCAFG00000010996 DLLETQSDLTGVQNVELEAESVEPR-----LSIQPIDPENQAVEPEAQAIEPKVQ----- CAVPO19_22_PE3 NOISO ---ESQGDLKNVQSVTPEDQSVEPDTQVAKLAVLA-------AEPEGQAT---------- CHOHOGS_4625_PE1 NOISO ------------------------------------------------------------ DANRE5_61_PE20 NOISO ------------------------------------------------------------ DASNOGS_4202_PE1 NOISO DLPETQDDLPGVYSVEPEAQSIEADTQAIELGFQAVEPDTQTVEPEAQAIEPEAQVVEPE DIPORGS_3897_PE1 NOISO DLSETQNYSAEIQSVKPNLQ----------------------IEPDSQATGPEGK----- ERIEUGS_5103_PE1 NOISO DLE-TQDGVTEGPSVELDAQDIEQQ--------------DQATEPKAQAIGAEAQNI--- GORGO11_127_PE16 NOISO DLLETQGDLTGIQ-------SVKPDTQAVEMKVQVTEPEGQAIEPEGQPI---------- HORSE7_34_PE29 NOISO DLLETQGDLTGIQSS--------IE-----PDTQAIELEGQAIEPKAQAIQPKAQ----- HS11_PE3255 NOISO DLLETQGDLTGIQ-------SVKPDTQAVEMKVQVTEPEGQAIEPEGQPI---------- LAMPA4421_PE1 NOISO DLLQPQGDLIDIQSVELEAWSVEPR-----PSTQDMELEGQAVKLKAQ------------ LOXAF50_17_PE7 NOISO DLSETQGDLPGIQNVKPDVQAGEPKGQAGETEAQAGEPEAQASETEAQAG---------- MACMU14_126_PE13 NOISO DLLETQGDLTGIQ-------SVEPDTQAVELKVQITEPEGQATEPEGQPI---------- MICMUGS_2724_PE11 NOISO DVPETEGDLTGIQSVEP-------DTQAIEPECEFGKPEDQAIELDGQ-A---------- MOUSE9_PE524 NOISO GLPESQSDVIDVQNVEPKASRIEPKTLGVEPDTQATGVECQTTEPEGQAV---------- MYOLUGS_3577_PE2 NOISO HLLETQGDLTGVQNVKLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----- OCHPRGS_3104_PE4 NOISO GLSESQSDLKEVHSVDL-------DTQAVDLGIQAVELKNQTIPPEGQVV---------- PANTR11_128_PE1 NOISO DLLETQGDLTGIQ-------SVKPDTQAVEMKVQVTEPEGQAIEPEGQPI---------- PIG9_52_PE4 NOISO DQLQAQSGLTGVLSVELEAQKIEPR-----LNTQDNELESQTIELKAQ------------ PONPY11_125_PE13 NOISO DLLETQGDLTGIQ-------SVKPDTQAVELKVQVTEPEGQAIEPEGQPI---------- PROCAGS_5410_PE2 NOISO DLSETQTDLSGIQSVEPEVQNIET-------DTQALEPEVQAGELETQAGEPET------ PTEVAGS_2173_PE1 NOISO DLLDTQSNLTEVQSVES--------------DTQAIEPEGQAVEPEAQAVEPDVP----- RABIT1_94_PE15 NOISO DLPESQSDLTDVHSVDLEAQSVEPSAQAVEFQVQAVELECQTVELEGQDI---------- RAT8_PE404 NOISO CLPESQSDVIDVQAVEPKASRIEPKEPGGEPDTQAAGMEFQTTEPDGQAV---------- SORARGS_4153_PE1 NOISO YLLETKDVRTEIQTTEP----------------------------YIHAAKPAAL----- SPETRGS_3506_PE8 NOISO ---ETKGDLIEVQSIEPEK-SIEPDVQAVDLEVQAIEPECQAIELEGQAF---------- TARSYGS_4834_PE1 NOISO XXXXXXXXXXXXX-------XXXXXXXXXXXXXXXXXPEGQ-IETEG-QA---------- TURTRGS_2035_PE12 NOISO DLLQTQGDLTGVCSVELEAQSVELR-----LGTQDIKLEGQAVEPKAQ------------ MATCH CONSENSUS DL?ETQ?DLTG?Q?V???????EP?????????Q??E?E?QA?EPE?Q????????????

AILMEGL193090_1_PE15 NOISO --AVKI--------------------------------------------------KT-Q BOVIN29_31_PE24 NOISO --AIKT--------------------------------------------------KT-K CALJA11_24_PE22 ENSCJAG00000008183 ----KI--------------------------------------------------E-TR CALJA11_24_PE23 ISOFORMIN ----KI--------------------------------------------------E-TR CANFA5_13_PE8 ENSCAFG00000010996 --DVKI--------------------------------------------------ET-Q CAVPO19_22_PE3 NOISO ----ET--------------------------------------------------E-TQ CHOHOGS_4625_PE1 NOISO ------------------------------------------------------------ DANRE5_61_PE20 NOISO --D--------------------------------------------------------- DASNOGS_4202_PE1 NOISO AKAVELKAGCGARSQAVEPEAQVVEPEQGCARSPGCGAGGQAVLLGAQDVEPYPDCDRNQ DIPORGS_3897_PE1 NOISO --V--------------------------------------------------------- ERIEUGS_5103_PE1 NOISO ----ET--------------------------------------------------ET-Q GORGO11_127_PE16 NOISO ----KT--------------------------------------------------E-TQ HORSE7_34_PE29 NOISO --DVKT--------------------------------------------------ET-Q HS11_PE3255 NOISO ----KT--------------------------------------------------E-TQ LAMPA4421_PE1 NOISO --AVKT--------------------------------------------------RT-R LOXAF50_17_PE7 NOISO ----ET--------------------------------------------------K-TQ MACMU14_126_PE13 NOISO ----KT--------------------------------------------------E-TQ MICMUGS_2724_PE11 NOISO ----KT--------------------------------------------------A-TQ MOUSE9_PE524 NOISO ----KT--------------------------------------------------G-IQ MYOLUGS_3577_PE2 NOISO --XXXX--------------------------------X-----------------XX-X OCHPRGS_3104_PE4 NOISO ----QT--------------------------------------------------D-TQ PANTR11_128_PE1 NOISO ----KT--------------------------------------------------E-TQ PIG9_52_PE4 NOISO --AVKI--------------------------------------------------ETPK PONPY11_125_PE13 NOISO ----KT--------------------------------------------------E-TQ PROCAGS_5410_PE2 NOISO --------------------------------------------------------E-IQ PTEVAGS_2173_PE1 NOISO --VVKT--------------------------------------------------ET-Q RABIT1_94_PE15 NOISO ----QT--------------------------------------------------D-TQ RAT8_PE404 NOISO ----KT--------------------------------------------------E-IQ SORARGS_4153_PE1 NOISO --AAE---------------------------------------------------TETQ SPETRGS_3506_PE8 NOISO ----KT--------------------------------------------------E-TL TARSYGS_4834_PE1 NOISO ----KT--------------------------------------------------E-TQ TURTRGS_2035_PE12 NOISO --AVKT--------------------------------------------------KT-Q MATCH CONSENSUS ????KT??????????????????????????????????????????????????E??Q

AILMEGL193090_1_PE15 NOISO GIMPEAQIVELEDGSIVSEVQD-LLPK--------------------------------- BOVIN29_31_PE24 NOISO SCILKDQTVGLEDGDIALEVQD-FPLQ--------------------------------- CALJA11_24_PE22 ENSCJAG00000008183 GIRLKPQSIELEEGSIVLETQD-FLPPNQLFLSE--NQDVLL------------------ CALJA11_24_PE23 ISOFORMIN GIRLKPQSIELEEGSIVLETQD-FLPPNQLFLSE--NQDVLL------------------ CANFA5_13_PE8 ENSCAFG00000010996 GILPEAQNIELEDESIMSKVQD-LLPK--------------------------------- CAVPO19_22_PE3 NOISO DIMVKACNIELEDGNTELGLTLHFLLKPQVLTVR----------HHQVSTRDKAEQKGEK CHOHOGS_4625_PE1 NOISO --------------------PE-FLSK--------------------------------- DANRE5_61_PE20 NOISO --------VEAEDE--MLLGQH-DQPL--------------------------------- DASNOGS_4202_PE1 NOISO GVMLEARSMDLEDASITLEARD-FLPL--------------------------------- DIPORGS_3897_PE1 NOISO -MKTETVSTELEDGNIEMVVQD-LLSN-------CHHQHSIP------------------ ERIEUGS_5103_PE1 NOISO ESIPEVQTTAPGGRSIVLRGQR-FLPK--------------------------------- GORGO11_127_PE16 NOISO GIMLKAQSIELEEGSIVLKTQD-FLPTNQALLTK--NQDVLL------------------ HORSE7_34_PE29 NOISO GIMLEAQSTEPEDERIALKIQD-FQPL--------------------------------- HS11_PE3255 NOISO GIMLKAQSIELEEGSIVLKTQD-FLPTNQALLTK--NQDVLL------------------ LAMPA4421_PE1 NOISO SVLLKTQSVELEEGNIVLEGQD-FLPQ--------------------------------- LOXAF50_17_PE7 NOISO GVMFKAQSIERENESIVLEAHD-FLPQNQDFLPK--DQNFLS-------------K---- MACMU14_126_PE13 NOISO GIMLKAQNIELEERSIVLETQD-FLPPNQAFLTK--NQDVLL------------------ MICMUGS_2724_PE11 NOISO GFILKAQSFELGDGSFVLAAQH-FLSPNQTFLPK--DQDILP-------------KDHYQ MOUSE9_PE524 NOISO DV-PKVQTVEL-DGNTELEAQD-FLPSHQAFLSR--DTDCLP-------------NCQYQ MYOLUGS_3577_PE2 NOISO XXXXXXXXXXXXXXXXXXXXXX-XXXX--------------------------------- OCHPRGS_3104_PE4 NOISO GNMLEAQSVGLEDVSIELQTQN-FLPPNQTFLAK--DQNILPVYHILFEDQDNLRNCQNQ PANTR11_128_PE1 NOISO GIMLKAQSIELEEGSIVLKTQD-FLPTNQA---K--NQDVLL------------------ PIG9_52_PE4 NOISO SVMMKSQSIELEDGNIVSEVQD-FLPQ--------------------------------- PONPY11_125_PE13 NOISO GIMLKAQSIELEEGSIVLKTQD-FLPTNQAFLTK--NQDVLL------------------ PROCAGS_5410_PE2 NOISO GVVLEARSTKPEDESVMLEVQG-FLPL--------------------------------- PTEVAGS_2173_PE1 NOISO SIMLEVQSTELEDGSIILEARD-FLSP--------------------------------- RABIT1_94_PE15 NOISO NSMMKAQSVELEDESTELEAQN-FLPPNQAFLPK--DQNTLP-------------GYQDQ RAT8_PE404 NOISO DT-LKVQTVEL-DGDTELEAQD-SLPSHQAFLSR--DQDFLL-------------NCQYQ SORARGS_4153_PE1 NOISO EIMLETQSIELADRRVGLEGRV-FISP--------------------------------- SPETRGS_3506_PE8 NOISO GIMIKASSTEIENRNIELKAQD-FLPKNQAFLPKCEDQDSLP-------------QNPYQ TARSYGS_4834_PE1 NOISO GIMLKAQNIELEDESIVLEAQD-FLPQNQTFLTN--DLDVPP------------------ TURTRGS_2035_PE12 NOISO SVMLKDQSVELEDGNIVLEVQD-FLLQ--------------------------------- MATCH CONSENSUS G?MLKAQS?ELEDGSI?LE?QD?FLP??Q???????????????????????????????

AILMEGL193090_1_PE15 NOISO ---------------TQCVL----------------LKDRNIL-------------PRCQ BOVIN29_31_PE24 NOISO ---------------NQTFL----------------PTDQHIL-------------P--- CALJA11_24_PE22 ENSCJAG00000008183 --------------KGHCVLPKDQNILLKYQVQDFLPRDQHVLPKDQDIL------PKYQ CALJA11_24_PE23 ISOFORMIN --------------KGHCVLPKDQNILLKYQVQDFLPRDQ-------------------- CANFA5_13_PE8 ENSCAFG00000010996 ---------------EQSVL----------------PKDQNIL-------------PRCQ CAVPO19_22_PE3 NOISO TLLWQVSSVSLLNPSSRTSLEFLATVDLKYRIRNFGAKDHVLASR--------------- CHOHOGS_4625_PE1 NOISO ---------------DQGIL----------------PEDQNIL-------------LKSQ DANRE5_61_PE20 NOISO ------------------------------------------------------------ DASNOGS_4202_PE1 NOISO ---------------NQVYL---------YKDRGI-LKDQTIL-------------PKSQ DIPORGS_3897_PE1 NOISO --------------KDHCVLHEDQNILPKYQDQNFLPRNCHIL-------------PKSQ ERIEUGS_5103_PE1 NOISO ---------------DQDFL----------------PKDDNQX-------------XXXX GORGO11_127_PE16 NOISO --------------KDHCVLPKDQSILLKYQDQDFLSRDQHVLPKDQDIL------PKYQ HORSE7_34_PE29 NOISO ---------------NQAFL----------------PKDQNIL-------------PTYQ HS11_PE3255 NOISO --------------KDHCVLPKDQSILLKYQDQDFLPRDQHVLHKDQDIL------PKYQ LAMPA4421_PE1 NOISO ---------------NQAFL---------HTDEDFSPKDQNIL-------------LECP LOXAF50_17_PE7 NOISO -------------------------------DQDALLRD--------------------- MACMU14_126_PE13 NOISO --------------KDHCVLPKDQNILLKYQDQDFLPRDQHVLPKDQDIL------P--- MICMUGS_2724_PE11 NOISO DF----------LPRNKCVPPKDDNVLFKCQDQDFLPTD--------------------- MOUSE9_PE524 NOISO DS----------LPKGHCVLPNYWNVLPKYQNQHFLPVD--------------------- MYOLUGS_3577_PE2 NOISO ---------------XXXXX---------XX--XX-XXXXXXX-------------XXXX OCHPRGS_3104_PE4 NOISO DF----------PSRDLRVFPKNQNILLKCQNQDFLPKDHSVFSKDQDIL------PSCP PANTR11_128_PE1 NOISO --------------KDHCVLPKDQSILLKYQDQDFLPRDQHVLPKDQDIL------PKYQ PIG9_52_PE4 NOISO ---------------NQAFF----------------PKDQNIL-------------LKCQ PONPY11_125_PE13 NOISO --------------KDHCVLPKDQSILLKYQDQDFLPRDQHVLPKDQDIL------PKYQ PROCAGS_5410_PE2 NOISO ---------------NEVFL----------------PKDQNFL-------------SKDP PTEVAGS_2173_PE1 NOISO ---------------NQAFP----------------PKDQSIL-------------LKCQ RABIT1_94_PE15 NOISO DF--------VHVREDRDILPEDHNVLPNCQDQDFLPKEEDLLPKKLCVLPRDENILKCQ RAT8_PE404 NOISO GS----------LPKDHCVLPNYQNVLPKYQDQHFLPVA--------------------- SORARGS_4153_PE1 NOISO ---------------KQHVLSKDLGVLPKGYDQDFLLSGQSLP-------------QKSE SPETRGS_3506_PE8 NOISO DF----------LSRNQHVFPEDQNILHKYQDQDFLHDD--------------------- TARSYGS_4834_PE1 NOISO --------------EDNCILPNDQSIPLKYEDQDFLPRDQLVLPKDQNIL------LICQ TURTRGS_2035_PE12 NOISO ---------------NQAFL----------------PTDQHIL-------------P--- MATCH CONSENSUS ??????????????????VL????????K???Q?FLP?DQ??L?????????????????

AILMEGL193090_1_PE15 NOISO DQDFL---------LKDQDFPPKDQNILPE-----------CQDQHFLPRDQHVLPE--- BOVIN29_31_PE24 NOISO ------------------------------------------------------------ CALJA11_24_PE22 ENSCJAG00000008183 DQDFEPKN--QDFLSRDQHVLLKDRNILPK-----------CQDQDFLPKYQVWSGICKD CALJA11_24_PE23 ISOFORMIN ----------------DQHVLLKDRNILPK-----------CQDQDFLPKYQKANLN--- CANFA5_13_PE8 ENSCAFG00000010996 DQDFL--------LPKDQHFLPRDQVPR-------------------------------- CAVPO19_22_PE3 NOISO --------RMHRVLSSDQSVLPFDRPIDQLNRFSSTKPHLLYYHQSVPAKIQYEPSGEQV CHOHOGS_4625_PE1 NOISO NQDFI------------------------------------------------------- DANRE5_61_PE20 NOISO ----H------------------------------------------------------- DASNOGS_4202_PE1 NOISO DQYFI------------------------------------------------------- DIPORGS_3897_PE1 NOISO DQDFLQTD--QDFLLKDQCVLPKSQSIPSK-----------YQNQDFLSTDQNILPKCEV ERIEUGS_5103_PE1 NOISO XXXXX------------------------------------------------------- GORGO11_127_PE16 NOISO DQNFLPKD--QNFLSRDQHVLPKDQDILPK-----------YQDQNFLPKDQNFLSRDQH HORSE7_34_PE29 NOISO DQAFR---------PKDQHVLSKDQNILSK-----------CQDQDFPPEDPDFLPRDQG HS11_PE3255 NOISO DQNFLPKD--QNFLSRDQHVLPKDQDILPK-----------YQDQNFLPKDQNFLSRDQH LAMPA4421_PE1 NOISO EQDFL---------PKDQCALPRDQ--------------------HVFPKDQNILPTYQD LOXAF50_17_PE7 NOISO ----------QDVLPKNQSILPKDQDILPK-----------CQDQDFPPKDQVNQPSTRN MACMU14_126_PE13 NOISO ------------------------------------------------------------ MICMUGS_2724_PE11 NOISO ----------QDFLPRDHCFLPKDQNILPK-----------CQDQDFVPKDQEFLPRDSH MOUSE9_PE524 NOISO ----------QEFLPRNQLALPKEQNHPLQ-----------CQKQDLLPREQFPLL---- MYOLUGS_3577_PE2 NOISO XXXXX---------XX---XX--XX----------------------------XXXX--- OCHPRGS_3104_PE4 NOISO D---------EDFLPGDPCVLLKDQNILLD-----------YQEQNFLPKGHHVPLRK-- PANTR11_128_PE1 NOISO DQNFLPKD--QNFLSRDQHVLPKDQDILPK-----------YQDQNFLPKDQNFLSRDQH PIG9_52_PE4 NOISO DKDVL---------PKEQYVLPNNQNILPK-----------YQDHHFLTEDKNILPGCQE PONPY11_125_PE13 NOISO DQDFLPKD--QNFSFRDQHV---------------------------------------- PROCAGS_5410_PE2 NOISO --DFL---------LKDQDVVPKDQSILP------------------------------- PTEVAGS_2173_PE1 NOISO DQHFL---------RKDQHVLAKDQNILHR-----------CQNQHSLPKYQNVFPKDQ- RABIT1_94_PE15 NOISO NQDFLPKDRNKDFLPRDQCVLPEEQTILPN-----------YQDQDFLPKDQNFPFRDQH RAT8_PE404 NOISO ----------QEFLPTNQLALPKEQNHPLK-----------CQKQDLPPEDQFPLPRHQY SORARGS_4153_PE1 NOISO HQALQ---------PKDQDFLLSGQSLPQK-----------SEHQALLPKDQDFLLSGQ- SPETRGS_3506_PE8 NOISO ----------QDFLCRDQCVLPKDQNILLK-----------CQDQDFLPKDQY------- TARSYGS_4834_PE1 NOISO DQNCLPGN---------QSVLPKDQNILFK-----------CQDQDFLPKDQNFLPRDQC TURTRGS_2035_PE12 NOISO ------------------------------------------------------------ MATCH CONSENSUS ?Q??????????????DQ?VLPKDQ?IL??????????????Q?Q???P??Q????????

AILMEGL193090_1_PE15 NOISO ------DQNM-----QSKFQDQDFLPKDHHQC---------------------------- BOVIN29_31_PE24 NOISO -----KDQNI-----QPECQDQDFLPSDQQHITPVWTIYFLKKLSLLDEVFLAAFVCFES CALJA11_24_PE22 ENSCJAG00000008183 CY----ILYLIWRSMLGKKQFLDWSLKTPVLLRSVKMNNLLSLF------FSFLNQHSTQ CALJA11_24_PE23 ISOFORMIN ------------------------------------------------------------ CANFA5_13_PE8 ENSCAFG00000010996 ------------------------------------------------------------ CAVPO19_22_PE3 NOISO EQHREHFLFKTWCFLENKENEIEV---------LAQDQGSVEML------QRLVLKCFDS CHOHOGS_4625_PE1 NOISO -------------------------PKD-------------------------------- DANRE5_61_PE20 NOISO ----LHHQQ--------------------------------------------------- DASNOGS_4202_PE1 NOISO -------------------------SKDQXXXXXXXXXXXXX------------------ DIPORGS_3897_PE1 NOISO QDFLLKDQNIL-----HQYQEHDF------------------------------------ ERIEUGS_5103_PE1 NOISO ---------X---------------------------XXXXXXXXXXXXIFLGQ------ GORGO11_127_PE16 NOISO VL----PKD---QNILSKYQDQDFLPKDQDFLSR--DQHALPKD------WNILPKCQDQ HORSE7_34_PE29 NOISO DIIRRNKLLKVW---SGFCK--DYIIADLN--AHSWKKYIISSRLPLS----GKFTFFEN HS11_PE3255 NOISO VL----PKD---QNILPKYQGQDFLPKDQDFLSR--DQHVLPKD------WNILPKCQDQ LAMPA4421_PE1 NOISO HHFLTEDQNI-----LPKCEDQDFLPKDQHVLSTDQNIQ---------------PKCQDQ LOXAF50_17_PE7 NOISO QL----DQE--------------------------------------------------- MACMU14_126_PE13 NOISO ------------------------------------------------------------ MICMUGS_2724_PE11 NOISO ---------------------------------------VLSKD------QNILLKCQDQ MOUSE9_PE524 NOISO ------LRH--------------------------------------------------- MYOLUGS_3577_PE2 NOISO -----XXXXX-----XXXXX--XXXXXXXX-XXXXXXXX---------------XX---- OCHPRGS_3104_PE4 NOISO ------------QKLPPKWQVQDFLPKDHNFLSR--DQYVLPTN------QHIPSKYLDQ PANTR11_128_PE1 NOISO VL----PKD---QNILPKYQDQDFLPKDQDFLSR--DQHVLPKD------WNILPKCQDQ PIG9_52_PE4 NOISO QNFLLEDQNI-----LPSSQDQNFLPNGQHVLSKEQDVL---------------PTCQDQ PONPY11_125_PE13 NOISO -L----PKD---PNILPKYQDQDFLPKDQDFLSR--DQHVLPKD------WNILPKCRDQ PROCAGS_5410_PE2 NOISO -----EDQNI-----LPKCQEQDFLPKD-------------------------------- PTEVAGS_2173_PE1 NOISO --------NA-----LPKCQDQDFLPRY-------------------------------- RABIT1_94_PE15 NOISO VL----PNN---QNIPSNYQDQNFLPKDQNILPK--DYHVLPKD------QTFLSRWQDQ RAT8_PE404 NOISO IL----PIY--------------------------------------------------- SORARGS_4153_PE1 NOISO -SFLSEHQ--------------APLPKDQDSLLSGQSLS--------------------- SPETRGS_3506_PE8 NOISO ------------------------------------------------------------ TARSYGS_4834_PE1 NOISO ---------------------------------------VPTKD------QNILPKCQNQ TURTRGS_2035_PE12 NOISO -----KDQNV-----LPKCQDQDFLPTDQHVLLKDQNVQ---------------PKCQDQ MATCH CONSENSUS ????????????????????????????????????????????????????????????

AILMEGL193090_1_PE15 NOISO -FLPRDQV------PRPALHWRSIRPKIRRKRSTGSKLHGCNWAYLMPEFSPQPKVLVNL BOVIN29_31_PE24 NOISO LFLTQVPR-PALQQRLIRLRGKERDQQ------------EVNYLGLWLGLCGIEYSVLT- CALJA11_24_PE22 ENSCJAG00000008183 IFMPLSAWTAER----------------------------------WKKEWPISTQQY-- CALJA11_24_PE23 ISOFORMIN ------------------------------------------------------------ CANFA5_13_PE8 ENSCAFG00000010996 ----------------PALHQRS------------------------------------- CAVPO19_22_PE3 NOISO FFMPFNKGWLSV----------------------------------LQGVSPGCLSMW-- CHOHOGS_4625_PE1 NOISO ------------------------------------------------------------ DANRE5_61_PE20 NOISO ------------------------------------------------------------ DASNOGS_4202_PE1 NOISO --------------------XXX------------------------------------- DIPORGS_3897_PE1 NOISO ------------------------------------------------------------ ERIEUGS_5103_PE1 NOISO ------------------------------------------------------------ GORGO11_127_PE16 NOISO DFLPRDQGVLPK----------------------------------DQNILPICQDQD-- HORSE7_34_PE29 NOISO YFWQPS-------SALTADRWRK-------EWPTKRDQQEVDYLGLWVGLHGIEYNVLFY HS11_PE3255 NOISO DFLPRDQGVLPK----------------------------------DQNILPICQDQD-- LAMPA4421_PE1 NOISO NFLPRDE----------------------------------------------------- LOXAF50_17_PE7 NOISO ------------------------------------------------------------ MACMU14_126_PE13 NOISO ------------------------------------------------------------ MICMUGS_2724_PE11 NOISO DFLPRYQKI--------------------------------------------------- MOUSE9_PE524 NOISO ------------------------------------------------------------ MYOLUGS_3577_PE2 NOISO -XXXXX--------X-XXXXXXX----------------XXXXXXXXXXXXXXXXXXXXX OCHPRGS_3104_PE4 NOISO NFLPKDQSILPE----------------------------------DYQVLPSHQN---- PANTR11_128_PE1 NOISO DFLPRDQGVLPK----------------------------------DQNILPICQDQD-- PIG9_52_PE4 NOISO NFPPRDQSVVGFAGTVLQLIWRSIPGK------------HILPLSRWLIFKKHKILLINL PONPY11_125_PE13 NOISO D----------------------------------------------------------- PROCAGS_5410_PE2 NOISO ------------------------------------------------------------ PTEVAGS_2173_PE1 NOISO ------------------------------------------------------------ RABIT1_94_PE15 NOISO DFLSEDQ--------------------------------------------------H-- RAT8_PE404 NOISO ------------------------------------------------------------ SORARGS_4153_PE1 NOISO ------------------------------------------------------------ SPETRGS_3506_PE8 NOISO ------------------------------------------------------------ TARSYGS_4834_PE1 NOISO DFLRRYQGVLLK----------------------------------DQNILPICQDQD-- TURTRGS_2035_PE12 NOISO DFLPKD------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

AILMEGL193090_1_PE15 NOISO ------SFLTEQEANLKQPASILIGPRGRQAFPLDVHQDLLPRPQDQTSTRDK------- BOVIN29_31_PE24 NOISO ----------------YSLKMMASGRSQGEVFPLDICQDLLHRREDEAFISGKAEQKKDC CALJA11_24_PE22 ENSCJAG00000008183 -------FS-----HRFQGQLSTRGRRGREVPPLGVHQDLLCRHHQ-A--STG------- CALJA11_24_PE23 ISOFORMIN -----------------QPVSILIGRRGREVPPLGVHQDLLCRHHQAS--TGG------- CANFA5_13_PE8 ENSCAFG00000010996 ------ARPKPQKAGLKQGASILLGPREREAFPLAVHQDLQHRHQDQASIMDK------- CAVPO19_22_PE3 NOISO -------FL-----TSA---------------------------LFSN--SDS------- CHOHOGS_4625_PE1 NOISO ------------------------------------------------------------ DANRE5_61_PE20 NOISO ------------------------------------------------------------ DASNOGS_4202_PE1 NOISO ------------------------------------------------------------ DIPORGS_3897_PE1 NOISO ------------------------------------------------------------ ERIEUGS_5103_PE1 NOISO ------------------------------------------------------------ GORGO11_127_PE16 NOISO -------FL-----PRDQGYLPK----DQNILPICQDRDFLPRDLHIL--SND------- HORSE7_34_PE29 NOISO SIRFNSKILTMAETNLKEPASILIGGREREAFPLDVHQDL-HRHEDQASSRGKVEQKKER HS11_PE3255 NOISO -------FL-----PRDQGYLPK----DQNILPICQDRDFLPRDLHVL--SND------- LAMPA4421_PE1 NOISO ------------------------------------------------------------ LOXAF50_17_PE7 NOISO -------EE-----RDEQGLCQTIDRREREVFPLDVHQDLLHKCQDQATIRTD------- MACMU14_126_PE13 NOISO ------------------------------------------------------------ MICMUGS_2724_PE11 NOISO ------------------------------------------------------------ MOUSE9_PE524 NOISO -----------------------QDQREPHVLPKCQEHDVLSKAQ--------------- MYOLUGS_3577_PE2 NOISO XXXXXXXXXXXXKVRFKEPYSV-INEKGR------------------------------- OCHPRGS_3104_PE4 NOISO -------FP-----AGDHR----------------------------------------- PANTR11_128_PE1 NOISO -------FL-----PRDQGYLPK----DQNILPICQDRDFLPRDLHVL--SND------- PIG9_52_PE4 NOISO ------SFLTEQKANLKQPASLLVGRSRREVFPLDVHQDLLHRHEDQAFIRGK------- PONPY11_125_PE13 NOISO ---------------------------------------FLPRDLHVL--SND------- PROCAGS_5410_PE2 NOISO ------------------------------------------------------------ PTEVAGS_2173_PE1 NOISO ------------------------------------------------------------ RABIT1_94_PE15 NOISO -------FP-----FRDQHVLPD----NQNIPSNDQDQDF-------L--LED------- RAT8_PE404 NOISO -----------------------QDRRDPHVLPKCQDHDVLSKAQ--------------- SORARGS_4153_PE1 NOISO --------------------------------QKSEHQALLPKDQDSLLSGQSL------ SPETRGS_3506_PE8 NOISO ------------------------------------------------------------ TARSYGS_4834_PE1 NOISO -------FL-----PQDQNFLP--------------------SNLCVL--PID------- TURTRGS_2035_PE12 NOISO ----------------------------------------------------Q------- MATCH CONSENSUS ????????????????????????????????????????????????????????????

AILMEGL193090_1_PE15 NOISO --------------------------KVRFKESYSDMSSEKGREDS--SLAGYQYLPPKL BOVIN29_31_PE24 NOISO SQRDFRKCGLCFIPYCFTSSGVEKITKVCFKETYCDMN-EKGRKDF--SLASYQYLPPKL CALJA11_24_PE22 ENSCJAG00000008183 -------G--RVEKKKMFYIILKKTMKVHFKESYSDMTEKKGVKTF--LLADYRCLPPKS CALJA11_24_PE23 ISOFORMIN -------------------------RKVHFKESYSDMTEKKGVKTF--LLADYRCLPPKS CANFA5_13_PE8 ENSCAFG00000010996 --------------------------KVRFKESYSDMSSEEEREGF--SVAGHQYLPPNL CAVPO19_22_PE3 NOISO -------PSLPWSPCCHGFNSLPSKNRRGKKEPPPSITRKKKRTVFQVSLKQFSCQLPPS CHOHOGS_4625_PE1 NOISO -------------------------QKVRFKEPCSDNTDEKGRE---------------L DANRE5_61_PE20 NOISO ------------------------------------------------------------ DASNOGS_4202_PE1 NOISO --------------------------XXXXX--X-----XXX------------XXXXXX DIPORGS_3897_PE1 NOISO ---------------------QSKNQKVRFQEPFSDRTDEKGREVP--SV-DHQYLPSKF ERIEUGS_5103_PE1 NOISO ------------------------------------------------------------ GORGO11_127_PE16 NOISO -------Q--NILPKCQDQDFLPKYQKVHFKEPYSDMTDEKGREDF--SLADYQCLPPKS HORSE7_34_PE29 NOISO -------------------------PKVHFKEPYSDTTNEKGREDF--SLAGYQYLPPKL HS11_PE3255 NOISO -------Q--NILPKCQDQDFLPKYQKVHFKEPYSDMTDEKGREDF--SLADYQCLPPKS LAMPA4421_PE1 NOISO --------------------------KVHFKESCFDMTSEKKR-HP--SLAGYQSLPPKL LOXAF50_17_PE7 NOISO -------KKYSFLFYFIMFDIILRFKKVRFREPYSDTTEEREREDF--ALNVF------- MACMU14_126_PE13 NOISO ------------------------------------------------------------ MICMUGS_2724_PE11 NOISO ------------LPKY-------QDQKVHFKEPYSNMTDEKRRGDF--SLDMFL------ MOUSE9_PE524 NOISO ----------NYLHNYQEQDLQLQNQEVNSKEPLSDITDGKGREIF--SLDMFSK----- MYOLUGS_3577_PE2 NOISO ---------------------DGFSLEVRFKEPYSVIN-EKGRDGF--SLAGYQSPTPKV OCHPRGS_3104_PE4 NOISO -----------V--IHNTQNIQPKCQKVHCKETNPDVADEKGREDF--SLKDYQCQPPKL PANTR11_128_PE1 NOISO -------Q--NILPKCQDQDFLPKYQKVHFKEPYSDMTDEKGREDF--SLADYQCLPPKS PIG9_52_PE4 NOISO --------------------------KVRFKESYCDMT-EKGREDF--SLAGYQYLTPKF PONPY11_125_PE13 NOISO -------Q--NILPKCQDQDFLPKYQKVHFKEPHSDMTDEKGREDF--SLADYQCLPPKS PROCAGS_5410_PE2 NOISO -------------------------QKVRFKEPYSDMTD-ERREVL--VLADCQYLPPEL PTEVAGS_2173_PE1 NOISO -------------------------QKVRFKEPYSDMINEKGRGDF--SLAGHRYLPPKL RABIT1_94_PE15 NOISO -------Q--NTLPKGQKQGFLPKYQKVRFKEPYSDMTNEEGREDF--SLVDYQYQSPKL RAT8_PE404 NOISO ----------NYLHSYQEQDLPLQSQEVNFKEPFFDITDGKGREMF--FLASYHK----- SORARGS_4153_PE1 NOISO -------------------PQKSEHQKVRFKEPQRGFSPL-------------------- SPETRGS_3506_PE8 NOISO --------------------------KVHFLEPFS---DEEGREDF--SLDMFL------ TARSYGS_4834_PE1 NOISO -------Q--NILPKCWDQDFLPKDQKVHFKEPYSDVTDEKERENF--SLVDDQYLPPKP TURTRGS_2035_PE12 NOISO --------------------------KVRFKESYCDMTNEKGREDF--SLAGYQYLPPKL MATCH CONSENSUS ??????????????????????????KV?FKEPYSDMT?EKGRE?F??SLA?YQ?LPPK?

AILMEGL193090_1_PE15 NOISO QDQTFLRDQK-LPSFMRAEGMSDELPLEYHQYVEP--KTQNRA----SPREQSKYINQPS BOVIN29_31_PE24 NOISO QYQASIRDQV-YCSYMNNCEKKDELTLGCHQYIQP--KMKSYDQPRQHIKEQSKCIMQPS CALJA11_24_PE22 ENSCJAG00000008183 QDQDNIRNQQ-SVSFSE-RRESEELLLDYHQYVVP--KIQGQD----SPREQNKHIKPPS CALJA11_24_PE23 ISOFORMIN QDQDNIRNQQ-SVSFSE-RRESEELLLDYHQYVVP--KIQGQD----SPREQNKHIKPPS CANFA5_13_PE8 ENSCAFG00000010996 QDQTFIRDQQ-MASFMRAEGISDELALEYQQCAKP--KTQDRA----SLREESKYIKQPS CAVPO19_22_PE3 NOISO QRPEMSKEKQ-QAVSKREGETMQHVPVPFRILTGQ--ALLGHE----SLKPSSSSLDVTQ CHOHOGS_4625_PE1 NOISO QDQAFVRNQQ-PSSLMRGERTRKELPLEYCQYVTP--NIQDQA----SSREQNKYIRQPS DANRE5_61_PE20 NOISO ------------------------------------------------------------ DASNOGS_4202_PE1 NOISO XXXXXXXXXXQPSYFMRGERVREEFPLEYCHYVTP--KIQDQAS---SREKQDMFPKQPS DIPORGS_3897_PE1 NOISO RFQDFIGDQQ-PSSFMREKREGEELLPEYHQYVPP--KIQDQV----SYREENKYGKQPS ERIEUGS_5103_PE1 NOISO -----------PSFFVTKERMR-----KEQQYIRP--KIQDCSSPKEVE----------- GORGO11_127_PE16 NOISO QDQDDIKNQQ-PASFMREERVREELPLDYHQYVVP--KIQDQD----SLREQNKHIKLPS HORSE7_34_PE29 NOISO QDQACIRDQQ-PSSFMRE--DGDELPQEYHQFVKH--KIQDQA----SSREQIEWNTQPS HS11_PE3255 NOISO QDQDDIKNQQ-PASFMREERVREELPLDYHQYVVP--KIQDQD----SPREQNKHIKLPS LAMPA4421_PE1 NOISO QDQAFIRDEL-LSSFMR----GDELALEYHQYVKA--KMQDKAFPG-----GQKYSKRPS LOXAF50_17_PE7 NOISO -------PKQ-PSSFLREEKVRQELPQENHQCVVP--KIQDKT----SSREQQPQQ---S MACMU14_126_PE13 NOISO ------------------------------------------------------------ MICMUGS_2724_PE11 NOISO --------KQ-PSSFMRDERVREEL-LEYHQYVIPINKIQDQA----SPREQVEQKTVG- MOUSE9_PE524 NOISO --------KP--STFMRRERGDEELPLDSPQCAPP--QIQDQV----FLREQSQQPSV-R MYOLUGS_3577_PE2 NOISO QDQVCIRDQVKQNXX--------------------------------------------- OCHPRGS_3104_PE4 NOISO QFQDLLRDPH-PSCFIG-----KELPVEYFQCAPS--QVQHLA----SPTKESKCIHT-S PANTR11_128_PE1 NOISO QDQDDIKNQQ-PASFMREERVREELPLDYHQYVVP--KIQDQD----SPREQNKHIKLPS PIG9_52_PE4 NOISO QDQVIIRDQKHLSSFMR---ERDDLTLEHHQYVKP--KMQGQA----SLGEQNKYIKELS PONPY11_125_PE13 NOISO QDQDDIKNQQ-PASFMREERVREELPLDCHQYVVP--KIQDQD----SPREQNKHIKPPS PROCAGS_5410_PE2 NOISO QDQPCIRDQQ-PSPLLREEKVPQELPQESHRCFMR--KIQDQA----SVREQNKYIK--- PTEVAGS_2173_PE1 NOISO QDQAFVRNQQ-LSFFMREERVRDELPQEYPQYVNP--QIQDQA----SPGDQNKCTKQPS RABIT1_94_PE15 NOISO QIQDVIRDQQ-PSYFMREEKVREELPLGYHQRVPS--KVQQQA----SLREQNKYIKQPS RAT8_PE404 NOISO --------PG-NSNKLSHSKGSKELPLECPHYASP--QIQNQV----FLREQSQQPSV-R SORARGS_4153_PE1 NOISO ---------------HKSQIRSEEDSPLGHQYVKP--EIQSKSREQ------AEXXXXXX SPETRGS_3506_PE8 NOISO ---------K-PSPFRTEERVREELPLY--HYVPS--KIQDQT----SLGEQVEPHTEK- TARSYGS_4834_PE1 NOISO QDKDFIRDQQ-PLSFMREGRVKEEFPLGYHEYVTP--KIQDQT----TSREYNKCIKQPS TURTRGS_2035_PE12 NOISO QDQAFIRDQQ-LSSFMREEREREELTLGCHQNVKP--KMQDQA----SPIEQNKCIKQLS MATCH CONSENSUS QDQ??IR?QQ?PSSFMR?ER???ELPL?YHQYV?P??KIQDQ?????S?REQ?K?IK?PS

AILMEGL193090_1_PE15 NOISO SCEKWEIER-MASGVP-----------------------------------------SVY BOVIN29_31_PE24 NOISO CFKKSELGRGIASGVW-----------------------------------------LVG CALJA11_24_PE22 ENSCJAG00000008183 SFEKWKIARRNTSGVPLLSY--------------------------------------NR CALJA11_24_PE23 ISOFORMIN SFEKWKIARRNTSGVPLHRNSEQALHD----ITDKRWRKLSEHHGYILHESQDTGSAREQ CANFA5_13_PE8 ENSCAFG00000010996 SFEKWEIERRLAFGVPPHKNYGQALHNMTEERWRKELFLEPHEYVLRDTHDPGSAGQQVY CAVPO19_22_PE3 NOISO GTGQWQKRSVNGCGVNLG-----------------------------------------V CHOHOGS_4625_PE1 NOISO SFEKWEIERGYTSGVS-----------------------------------------SVY DANRE5_61_PE20 NOISO ----------IQDGTPTEKTLLKTLKNLVHAVLN-MLIYE-----------------PDR DASNOGS_4202_PE1 NOISO SFETRESEGGIASGVL-----------------------------------------SVY DIPORGS_3897_PE1 NOISO SLEKQETARRLASGALS------------------------------------------- ERIEUGS_5103_PE1 NOISO ------IAVGSAXXXXXXXXX-------------------XXXXXXXXXXXXXXXXXXVF GORGO11_127_PE16 NOISO SFEKWEIARGNTPGVPLA-----------------------------------------Y HORSE7_34_PE29 NOISO SFEKWEIERGISPGVP-----------------------------------------SVY HS11_PE3255 NOISO SFEKWEIARGNTPGVPLA-----------------------------------------Y LAMPA4421_PE1 NOISO SFEKWEIEKGIASGVP-----------------------------------------SVG LOXAF50_17_PE7 NOISO SFGTAEREQ---EDLLLDGH---------------------HHLPPRHHKEASSRRQKVY MACMU14_126_PE13 NOISO ------------------------------------------------------------ MICMUGS_2724_PE11 NOISO -------------GLYYXXXXXXXXX---------------XXXXXXXXXXXXXXXXXVY MOUSE9_PE524 NOISO TAERWQ------EDLYLSG---------------------HECLPPRQRRDTCSRQQQVY MYOLUGS_3577_PE2 NOISO -----------------------------------------------------XXXXXVY OCHPRGS_3104_PE4 NOISO TFEKLTSKEIAS-GVLS-----------------------------------------VC PANTR11_128_PE1 NOISO SFEKWEIARGNTPGVPLA-----------------------------------------Y PIG9_52_PE4 NOISO SFEKWEIERGIASGVP-----------------------------------------WIG PONPY11_125_PE13 NOISO SFEKREIARGNTPGVPLA-----------------------------------------Y PROCAGS_5410_PE2 NOISO RFEEWEIVRVVACGVP-----------------------------------------SVY PTEVAGS_2173_PE1 NOISO SFERWEFER-IAFRVP-----------------------------------------SVY RABIT1_94_PE15 NOISO SFETKKIQSGHTGGVRLAFI--------------------------------------RI RAT8_PE404 NOISO TAERWQ------EDLYLSG---------------------HECLPPRQRRDTCSRRQQLC SORARGS_4153_PE1 NOISO XXXXXXX--------------------------------------XXXXXXXXXXXXXAY SPETRGS_3506_PE8 NOISO -------------GLTXXXXXXXXX---------------XXXXXXXXXXXXXXXXXXVY TARSYGS_4834_PE1 NOISO SFEKWEIARV-ASGLPLV-----------------------------------------Y TURTRGS_2035_PE12 NOISO SFEKWEVERRVASEVP-----------------------------------------SVG MATCH CONSENSUS SFEKWEI?R????GVP??????????????????????????????????????????VY

AILMEGL193090_1_PE15 NOISO DAYQSRLNTEFQTPLMLQSGVDQEEDKKERQ-KQYLRYRRLFMDIEREQVKEQQRQKEH- BOVIN29_31_PE24 NOISO DEYQSRLNTEFQTPLALQSGVSQEEDKKERQ-KQYLRYRRLFMDIEREQVKEQQRQKEH- CALJA11_24_PE22 ENSCJAG00000008183 TYYQSGSSTEFQSSLACQSGIDKEEDKKERQ-KQYLRHRRLFMDIEREQVKEQQRQKVQ- CALJA11_24_PE23 ISOFORMIN TYYQSGSSTEFQSSLACQSGIDKEEDKKERQ-KQYLRHRRLFMDIEREQVKEQQRQKVQ- CANFA5_13_PE8 ENSCAFG00000010996 DEYQSRLNTEFQTPLTFQSGVDQEEDKKERQ-KQYLRYRRLFMDIEREQVKEQQRQKEH- CAVPO19_22_PE3 NOISO YKYQSGLGAEFQTSLANHSGIDKEERKKERH-VLNFSSKLLWFRIEREQVKEQKRQKAQQ CHOHOGS_4625_PE1 NOISO DKYQSGFNTEFQ---ALKSGVDEEEDKKE------------------------------- DANRE5_61_PE20 NOISO TASCTGFTTDYRASQVLWPHENQEELKRQRQ-SQFLMYRRHFMDIEREQVKEHKRHRKH- DASNOGS_4202_PE1 NOISO DEYQSGLNTELQAPVVLQSGVDEEEDKKERQ-KQYLRYRRLFMDIEREQVKEQQRQKEH- DIPORGS_3897_PE1 NOISO ------------------------------------------------------------ ERIEUGS_5103_PE1 NOISO NENQSGLNSEFQTLPTFQSGLDQEEDKKERQ-KQYLRYRRLFMDIEREQVKEQQRQKEH- GORGO11_127_PE16 NOISO DRYQSGLSTEFQAPLAFQSGVDKEEDKKERQ-KQYLRHRRLFMDIEREQVKEQQRQKEQ- HORSE7_34_PE29 NOISO DEYQSGLNTEFQTPLALQSGVDQEEDKKERQ-KQYLRYRRLFMDIEREQVKEQQRQKEH- HS11_PE3255 NOISO DRYQSGLSTEFQAPLAFQSDVDKEEDKKERQ-KQYLRHRRLFMDIEREQVKEQQRQKEQ- LAMPA4421_PE1 NOISO DEYQSGLNTEYQTPLAFQSGVNQEEDKKERQ-KQYLRYRRLFMDIEREQVKEQHRQKEQ- LOXAF50_17_PE7 NOISO DTDQSGLNTDFQALLALQSGLDQEENKKVRQ-KQYLRYKRLFMDIEREQVKEQQRQKER- MACMU14_126_PE13 NOISO ------------------------------------------------------------ MICMUGS_2724_PE11 NOISO DEYQSGLSTEFQAPLAFQSGVDQEEDKKERQ-KQYLRHRRLFMDIEREQVKEQQRQKEQ- MOUSE9_PE524 NOISO EEYRSGLSTEQQALLAFQSGVDQEEDKKERQ-KQYLRHRRLFMDIEREQVKEQNRQRER- MYOLUGS_3577_PE2 NOISO DKYQSGWNTEFQTPLGLQFGVSQEEDKKERQ-KRYLRYRRF-MDXXXXXXXXXXXXXXX- OCHPRGS_3104_PE4 NOISO SNCQ--SRWESRAPFAFRPGVDQEEDKKERQ-RQYLRHRRLFMDIEREQVKEKR-QKEQ- PANTR11_128_PE1 NOISO DRYQSGLSTEFQAPLAFQSDVDREEDKKERQ-KQYLRHRRLFMDIEREQVKEQQRQKEQ- PIG9_52_PE4 NOISO DECQAGLNPEFQTLLALQSGVNQEEDKKERQ-KQYLRYRRLFMDIEREQVKEQQRQNEH- PONPY11_125_PE13 NOISO DGYQSGLSTEFQAPLAFQSGVDKEEDKKERQ-KQYLRHRRIFMDIEREQVREQQRQKEQ- PROCAGS_5410_PE2 NOISO DAYHSGLNTEFQAPLVLRSGVDQEEEKKVRQ-KQYLRYKRLFMDIEREQVKEQQRQKEH- PTEVAGS_2173_PE1 NOISO DECQSGLNTEFQPSLALQTGVDQEEDKKERQ-RQYLRYRRLFMDIEREQVKEQQRQKEH- RABIT1_94_PE15 NOISO VYNQSRLSTEFRAPLAFQSGVDQEEDKKEVCNDNALGHQYFFYDVEREQVKQQQRQKEQ- RAT8_PE404 NOISO EEYRSGPSTEQQALLPFQSGVDQEEDKKERQ-KQYLRHRRIFMDIEREQVKEQNRQREQ- SORARGS_4153_PE1 NOISO EDCQSGLNSEFQTSLPFQSGVDQE-DKKERQ-KQFLRFRRLFMDIEREQVKEQLRQKL-- SPETRGS_3506_PE8 NOISO NDYQSGLSNEFQTPLAFQSGVDKEEDKKERQ-KQYLRHRRLFMDIEREQVKEQKRQKEQ- TARSYGS_4834_PE1 NOISO DKYQSRLSTEFQAPLAFQSGVYQEEEKKERQ-RQYLRYRRLFMDIEREQVKEKQRQKEQ- TURTRGS_2035_PE12 NOISO GEYQSGLNTEFQTPLALQSGVSQEEDKKERQ-KQYLRYRRLFMDIEREQVKEQQRQKEQ- MATCH CONSENSUS D?YQSGL?TEFQ?PLA?QSGVDQEEDKKERQ?KQYLR?RRLFMDIEREQVKEQQRQKE??

AILMEGL193090_1_PE15 NOISO QKKVEKIKKKKEQQRYAEEQRILRVNFHEELY--SGEKMSDILAQLKLEELKGAREKQ-Q BOVIN29_31_PE24 NOISO K----------------------------------------------------------- CALJA11_24_PE22 ENSCJAG00000008183 KMKIEKIKKKREQERYAEEQRILRMNFHEELY--SGEKMSEILAQLQLEENKGAREKQ-Q CALJA11_24_PE23 ISOFORMIN KMKIEKQTLEK------------------------------------------------- CANFA5_13_PE8 ENSCAFG00000010996 QKKVEKDRSMK------------------------------------------------- CAVPO19_22_PE3 NOISO KKQIEKIKQKKEQQCFVEEQRTLRLGSHRAPY--SEQKMSDRFSQLQLEEMKGAKEKM-Q CHOHOGS_4625_PE1 NOISO ------------------------------------------------------------ DANRE5_61_PE20 NOISO IKRTARIKNEKEHARKAEEKKMEQQRQQEEERKDEAEREYLILERLRLDEEEEAEEKA-Q DASNOGS_4202_PE1 NOISO K----------------------------------------------------------- DIPORGS_3897_PE1 NOISO ------------------------------------------------------------ ERIEUGS_5103_PE1 NOISO KKKIEKIKKKKEQQRFAEEQRLLRMKCPEEPY--SEEKMSEILAQLQLEEIKGAR----- GORGO11_127_PE16 NOISO KKKIEKIKKKREQERYAEEQRILRMNFHEDPY--SGEKLSEILAQLQLEEIKGTREKQ-Q HORSE7_34_PE29 NOISO RKKIEKIKKKKEQQRYAEEQRILRMSFHKEPD--SGEKMSEILAQLQLEEITGAREKQ-Q HS11_PE3255 NOISO KKKIEKIKKKREQECYAAEQRILRMNFHEDPY--SGEKLSEILAQLQLQEIKGTREKQ-Q LAMPA4421_PE1 NOISO R----------------------------------------------------------- LOXAF50_17_PE7 NOISO KKKIEKIKKKKEQESYAEEQRIPRVTRPEEPY--SGENMSEILAQLQLSEFSHNFLKREL MACMU14_126_PE13 NOISO ------------------------------------------------------------ MICMUGS_2724_PE11 NOISO KKKIE------------------------------------------------------- MOUSE9_PE524 NOISO KRRIEKIKKKKEQQRYAEEQRLLRMNCHEEPY--SEEKISDVLAQLQLEEIKGAREKQ-Q MYOLUGS_3577_PE2 NOISO XXXXXXIKRKSEQQRYAEEQRILRMNFHEEPY--SGEKMSEMLAQLQLEEMKEAR----- OCHPRGS_3104_PE4 NOISO K----------------------------------------------------------- PANTR11_128_PE1 NOISO K----------------------------------------------------------- PIG9_52_PE4 NOISO RKKIEKIKKKKEQQRYAEEQRILRMNFHEEPY--SGEKMSEILAQLQLEEIKGAKEKQ-- PONPY11_125_PE13 NOISO K----------------------------------------------------------- PROCAGS_5410_PE2 NOISO K----------------------------------------------------------- PTEVAGS_2173_PE1 NOISO R----------------------------------------------------------- RABIT1_94_PE15 NOISO KKKIEKIKKKKEQERYAEEQRVLRENLHKEPC--SGEKMSEKLAQLQLEEKKGAREKQ-Q RAT8_PE404 NOISO KRRAEKIKKRKEQERYAEEQRLLRVNCPEEPC--SEENISDVLAQLQLQEIKGAREKQ-Q SORARGS_4153_PE1 NOISO KKKVEKIKKKKEQQRHAEEQQII-MNLQEEPH--SGEEIVP-DDQLQLEEREESR----- SPETRGS_3506_PE8 NOISO KKKIEKIKKKKEQQRYAEEQKIERMNFKEEPC--SGEKMSGMLAQLQLEELKETR----- TARSYGS_4834_PE1 NOISO K----------------------------------------------------------- TURTRGS_2035_PE12 NOISO R----------------------------------------------------------- MATCH CONSENSUS K???EKIK???E??????E??????????????????????????L?L?E??????????

AILMEGL193090_1_PE15 NOISO -----QREKEC-QRYIEALRARIQEKMRLYNITLPPLCCCGTDFWDAHPDTCANNCIFYK BOVIN29_31_PE24 NOISO ------------------------------------------------------------ CALJA11_24_PE22 ENSCJAG00000008183 -----QREKEYLSRYVEALRAQIQEKMQLYNITLPPLCCCGPDFWDAHPDTCANNCIFYK CALJA11_24_PE23 ISOFORMIN ------------------------------------------------------------ CANFA5_13_PE8 ENSCAFG00000010996 ------------------------------------------------------------ CAVPO19_22_PE3 NOISO -----QKEKEY-VRYVEALRAQVQEKMKLYNITLPPLCFCGPDFWDAHPDTCANNCIFYK CHOHOGS_4625_PE1 NOISO ------------------------------------------------------------ DANRE5_61_PE20 NOISO RRERTKRIKES-KRYIQAMRALMKEKLEKDKVELPALCCCGDTFWDSNPETCANNCIFYN DASNOGS_4202_PE1 NOISO ------------------------------------------------------------ DIPORGS_3897_PE1 NOISO ------------------------------------------------------------ ERIEUGS_5103_PE1 NOISO ------------------------------------------------------------ GORGO11_127_PE16 NOISO ------REKEY-LRYVEALRAQIQEKMQLYNITLPPLCCCGPDFWDAHPDTCANNCIFYK HORSE7_34_PE29 NOISO -----QREKEY-QRYVEALRAQIQEKMQLYNVTLPPLCCCGPDFWDAHPDTCANNCIFYK HS11_PE3255 NOISO ------REKEY-LRYVEALRAQIQEKMQLYNITLPPLCCCGPDFWDAHPDTCANNCIFYK LAMPA4421_PE1 NOISO ------------------------------------------------------------ LOXAF50_17_PE7 NOISO -----AVSPHTFLQYVEVLRAQIQEKMQRHNITLPPLCCCGPDFWDAHPDTCANSCIFYK MACMU14_126_PE13 NOISO ------------------------------------------------------------ MICMUGS_2724_PE11 NOISO ------------------------------------------------------------ MOUSE9_PE524 NOISO -----QREKEY-IRYVEALRAQVQEKMKLYNITLPPLCCCGPDFWDAHPDTCANNCIFYK MYOLUGS_3577_PE2 NOISO ------------------------------------------------------------ OCHPRGS_3104_PE4 NOISO ------------------------------------------------------------ PANTR11_128_PE1 NOISO ------------------------------------------------------------ PIG9_52_PE4 NOISO -----QKEKEY-QRYVEALRAQIQEKMQLYNITLPPLCCCGPDFWDAHPDTCANNCIFYK PONPY11_125_PE13 NOISO ------------------------------------------------------------ PROCAGS_5410_PE2 NOISO ------------------------------------------------------------ PTEVAGS_2173_PE1 NOISO ------------------------------------------------------------ RABIT1_94_PE15 NOISO -----QREKEY-LRYVEALRAQIQEKMRLYNITLPPLCCCGPDFWDAHPDTCANNCIFYK RAT8_PE404 NOISO -----QREKEY-VRYVEALRAQVQEKMKLYNITLPPLCCCGPDFWDAHPDTCANNCIFYK SORARGS_4153_PE1 NOISO ------------------------------------------------------------ SPETRGS_3506_PE8 NOISO ------------------------------------------------------------ TARSYGS_4834_PE1 NOISO ------------------------------------------------------------ TURTRGS_2035_PE12 NOISO ------------------------------------------------------------ MATCH CONSENSUS ????????????????????????????????????????????????????????????

AILMEGL193090_1_PE15 NOISO NHRAYTRALRSVINSCDIPEGTSTVRVAMHNLASAHRRTLKNL-- BOVIN29_31_PE24 NOISO --------------------------------------------- CALJA11_24_PE22 ENSCJAG00000008183 NHKAYTRALHSVINSCDVSRGNSTLRVALHNFASAHRRTLKNL-- CALJA11_24_PE23 ISOFORMIN --------------------------------------------- CANFA5_13_PE8 ENSCAFG00000010996 --------------------------------------------- CAVPO19_22_PE3 NOISO NHQAYSRALCSVISSSDVSEGHSTLRNAIHNFASAHRRILKNM-- CHOHOGS_4625_PE1 NOISO --------------------------------------------- DANRE5_61_PE20 NOISO NPKAYAQALQSVLLSCDLKEGALMNRF------------------ DASNOGS_4202_PE1 NOISO ---------------------------------------------